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Conserved domains on  [gi|77681565|ref|NP_085154|]
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proline-rich transmembrane protein 1 isoform 1 [Homo sapiens]

Protein Classification

CD225/dispanin family protein( domain architecture ID 10517436)

CD225/dispanin family protein similar to Homo sapiens tumor suppressor candidate 5 (TUSC5), which may be involved in fat metabolism, and synapse differentiation-inducing gene protein 1 (SynDIG1), which may regulate AMPA receptor content at nascent synapses and have a role in postsynaptic development and maturation. CD225 is an interferon-inducible transmembrane protein associated with interferon induced cell growth suppression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CD225 pfam04505
Interferon-induced transmembrane protein; This family includes the human leukocyte antigen ...
 219-286 2.12e-23

Interferon-induced transmembrane protein; This family includes the human leukocyte antigen CD225, which is an interferon inducible transmembrane protein, and is associated with interferon induced cell growth suppression.


:

Pssm-ID: 461336  Cd Length: 68  Bit Score: 91.02  E-value: 2.12e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 77681565   219 PPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLC 286
Cdd:pfam04505   1 PPPDYLVWSIFSTLCCCLPLGIVAIVYSVKVRDRKAAGDYEGAQRASRTAKCLNIIALVLGLVVIILY 68
 
Name Accession Description Interval E-value
CD225 pfam04505
Interferon-induced transmembrane protein; This family includes the human leukocyte antigen ...
 219-286 2.12e-23

Interferon-induced transmembrane protein; This family includes the human leukocyte antigen CD225, which is an interferon inducible transmembrane protein, and is associated with interferon induced cell growth suppression.


Pssm-ID: 461336  Cd Length: 68  Bit Score: 91.02  E-value: 2.12e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 77681565   219 PPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLC 286
Cdd:pfam04505   1 PPPDYLVWSIFSTLCCCLPLGIVAIVYSVKVRDRKAAGDYEGAQRASRTAKCLNIIALVLGLVVIILY 68
 
Name Accession Description Interval E-value
CD225 pfam04505
Interferon-induced transmembrane protein; This family includes the human leukocyte antigen ...
 219-286 2.12e-23

Interferon-induced transmembrane protein; This family includes the human leukocyte antigen CD225, which is an interferon inducible transmembrane protein, and is associated with interferon induced cell growth suppression.


Pssm-ID: 461336  Cd Length: 68  Bit Score: 91.02  E-value: 2.12e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 77681565   219 PPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLC 286
Cdd:pfam04505   1 PPPDYLVWSIFSTLCCCLPLGIVAIVYSVKVRDRKAAGDYEGAQRASRTAKCLNIIALVLGLVVIILY 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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