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Conserved domains on  [gi|13540563|ref|NP_110414|]
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complement factor H-related protein 5 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 107-323 7.38e-15

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.69  E-value: 7.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  107 GDTVQIICNTGYSLQN-NEKNISCVERGWSTPPICsfTKGECHVPileANVD-AQPKKESYKVGDVLKFSCRKNLIRVGS 184
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQC--IKRRCPSP---RDIDnGQLDIGGVDFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  185 DSVQCyQFG------WSPNFPTCKGQvrSCGPPPQLSNGEvKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTT 258
Cdd:PHA02927 122 SKSYC-ELGstgsmvWNPEAPICESV--KCQSPPSISNGR-HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 13540563  259 LPTCveQVKTCGYiPELEYGYVQPSVP-PYQHGVSVEVNCRNEYAMIGNNMITCING-IWT-ELPMCV 323
Cdd:PHA02927 198 PPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGnTWQpELPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 287-504 3.57e-13

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 69.68  E-value: 3.57e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  287 YQHGVSVEVNCRNEY--AMIGNNMITCINGIWTELPMCVAthqlKRCKIAGVNIKTLLKLSGKEFNhnSRIRYRCSDIFR 364
Cdd:PHA02927  44 YNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDFG--SSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  365 Y---RHSVCINGK-----WNPEVDCTEKREqfCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRW 436
Cdd:PHA02927 118 LigeSKSYCELGStgsmvWNPEAPICESVK--CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  437 QSLPRCveSTAYCgPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR--NKQWSEPPRCL 504
Cdd:PHA02927 196 SDPPTC--QIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpgNTWQPELPKCV 262
PHA02954 super family cl31523
EEV membrane glycoprotein; Provisional
 11-146 2.00e-03

EEV membrane glycoprotein; Provisional


The actual alignment was detected with superfamily member PHA02954:

Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.45  E-value: 2.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563   11 SWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFsqvptGEVFYYSCEYNFVSPSKSFwtrITCTEEGWSPTPKCLRMCSFP 90
Cdd:PHA02954 118 SWNDTVTCPNAECQPLQLEHGSCQPVKEKYSF-----GEHITINCDVGYEVIGASY---ISCTANSWNVIPSCQQKCDIP 189

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563   91 FVKNGHseSSGLIHLEGDTVQIICNTGYSLQNNEKNiSCVERGWS-TPPICSFTKGE 146
Cdd:PHA02954 190 SLSNGL--ISGSTFSIGGVIHLSCKSGFTLTGSPSS-TCIDGKWNpVLPICVRSNEE 243
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 107-323 7.38e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.69  E-value: 7.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  107 GDTVQIICNTGYSLQN-NEKNISCVERGWSTPPICsfTKGECHVPileANVD-AQPKKESYKVGDVLKFSCRKNLIRVGS 184
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQC--IKRRCPSP---RDIDnGQLDIGGVDFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  185 DSVQCyQFG------WSPNFPTCKGQvrSCGPPPQLSNGEvKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTT 258
Cdd:PHA02927 122 SKSYC-ELGstgsmvWNPEAPICESV--KCQSPPSISNGR-HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 13540563  259 LPTCveQVKTCGYiPELEYGYVQPSVP-PYQHGVSVEVNCRNEYAMIGNNMITCING-IWT-ELPMCV 323
Cdd:PHA02927 198 PPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGnTWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 287-504 3.57e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 69.68  E-value: 3.57e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  287 YQHGVSVEVNCRNEY--AMIGNNMITCINGIWTELPMCVAthqlKRCKIAGVNIKTLLKLSGKEFNhnSRIRYRCSDIFR 364
Cdd:PHA02927  44 YNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDFG--SSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  365 Y---RHSVCINGK-----WNPEVDCTEKREqfCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRW 436
Cdd:PHA02927 118 LigeSKSYCELGStgsmvWNPEAPICESVK--CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  437 QSLPRCveSTAYCgPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR--NKQWSEPPRCL 504
Cdd:PHA02927 196 SDPPTC--QIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpgNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 449-503 1.99e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 1.99e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563 449 CGPPPSINNGDTTSfPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 503
Cdd:cd00033   1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 208-263 2.86e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.24  E-value: 2.86e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 13540563 208 CGPPPQLSNGEVKeIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTCV 263
Cdd:cd00033   1 CPPPPVPENGTVT-GSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 449-503 5.14e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 5.14e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563    449 CGPPPSINNGDTTSFPlSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 503
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
449-503 1.51e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.51e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563   449 CGPPPSINNGDTTSfPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 503
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 208-262 2.69e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 2.69e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563    208 CGPPPQLSNGEVKeIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTC 262
Cdd:smart00032   1 CPPPPDIENGTVT-SSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
208-262 9.49e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.26  E-value: 9.49e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563   208 CGPPPQLSNGEVkEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTC 262
Cdd:pfam00084   1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 11-146 2.00e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.45  E-value: 2.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563   11 SWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFsqvptGEVFYYSCEYNFVSPSKSFwtrITCTEEGWSPTPKCLRMCSFP 90
Cdd:PHA02954 118 SWNDTVTCPNAECQPLQLEHGSCQPVKEKYSF-----GEHITINCDVGYEVIGASY---ISCTANSWNVIPSCQQKCDIP 189

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563   91 FVKNGHseSSGLIHLEGDTVQIICNTGYSLQNNEKNiSCVERGWS-TPPICSFTKGE 146
Cdd:PHA02954 190 SLSNGL--ISGSTFSIGGVIHLSCKSGFTLTGSPSS-TCIDGKWNpVLPICVRSNEE 243
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 107-323 7.38e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.69  E-value: 7.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  107 GDTVQIICNTGYSLQN-NEKNISCVERGWSTPPICsfTKGECHVPileANVD-AQPKKESYKVGDVLKFSCRKNLIRVGS 184
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQC--IKRRCPSP---RDIDnGQLDIGGVDFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  185 DSVQCyQFG------WSPNFPTCKGQvrSCGPPPQLSNGEvKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTT 258
Cdd:PHA02927 122 SKSYC-ELGstgsmvWNPEAPICESV--KCQSPPSISNGR-HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 13540563  259 LPTCveQVKTCGYiPELEYGYVQPSVP-PYQHGVSVEVNCRNEYAMIGNNMITCING-IWT-ELPMCV 323
Cdd:PHA02927 198 PPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGnTWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 287-504 3.57e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 69.68  E-value: 3.57e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  287 YQHGVSVEVNCRNEY--AMIGNNMITCINGIWTELPMCVAthqlKRCKIAGVNIKTLLKLSGKEFNhnSRIRYRCSDIFR 364
Cdd:PHA02927  44 YNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDFG--SSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  365 Y---RHSVCINGK-----WNPEVDCTEKREqfCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRW 436
Cdd:PHA02927 118 LigeSKSYCELGStgsmvWNPEAPICESVK--CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  437 QSLPRCveSTAYCgPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR--NKQWSEPPRCL 504
Cdd:PHA02927 196 SDPPTC--QIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpgNTWQPELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 349-551 4.09e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 66.60  E-value: 4.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  349 FNHNSRIRYRCSDIFRYR-----HSVCINGKWNPEVDCTEKReqfCPPPPQIPNAQNMTTTVNYqdGEKVAVLCKENYLL 423
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQkmgpiYAKCTGTGWTLFNQCIKRR---CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  424 PEAKEIVCKDGRWQSL------PRCveSTAYCGPPPSINNGDTTSFPlSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQW 497
Cdd:PHA02927 119 IGESKSYCELGSTGSMvwnpeaPIC--ESVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 13540563  498 SEPPRCLdpcVVSEENMNKNNIQLKwrNDGKLYAKTGDAVEFQCKFPHKAMISS 551
Cdd:PHA02927 196 SDPPTCQ---IVKCPHPTISNGYLS--SGFKRSYSYNDNVDFKCKYGYKLSGSS 244
PHA02831 PHA02831
EEV host range protein; Provisional
 106-264 3.03e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 64.24  E-value: 3.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  106 EGDTVQIICNTGYslqnNEKNISCVERGWSTPPICsFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIR---- 181
Cdd:PHA02831  42 ENENLEYKCNNNF----DKVFVTCNNGSWSTKNMC-IGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNKLEkysi 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  182 VGSDSVQCYQFGWSPNFPTCKgqVRSCgPPPQLSNGEVKEIRKEEYgHNEVVEYDCNPNFIINGPKKIQC-VDGEWT-TL 259
Cdd:PHA02831 117 VGNETVKCINKQWVPKYPVCK--LIRC-KYPALQNGFLNVFEKKFY-YGDIVNFKCKKGFILLGSSVSTCdINSIWYpGI 192


                 ....*
gi 13540563  260 PTCVE 264
Cdd:PHA02831 193 PKCVK 197
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 48-201 4.69e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 63.52  E-value: 4.69e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563   48 GEVFYYSCE--YNFVSPSKSFWTRITCTEEGWSP-TPKC--LRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSLQN 122
Cdd:PHA02927 105 GSSITYSCNsgYQLIGESKSYCELGSTGSMVWNPeAPICesVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIG 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  123 NEkNISCVERGWSTPPICSFTKgeCHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTC 201
Cdd:PHA02927 185 NS-GVLCSGGEWSDPPTCQIVK--CPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNtWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 449-503 1.99e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 1.99e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563 449 CGPPPSINNGDTTSfPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 503
Cdd:cd00033   1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 208-263 2.86e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.24  E-value: 2.86e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 13540563 208 CGPPPQLSNGEVKeIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTCV 263
Cdd:cd00033   1 CPPPPVPENGTVT-GSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 163-323 3.18e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 58.52  E-value: 3.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  163 ESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG----WSPNFPTCkgQVRSCGPPPQLSNGEVKEiRKEEYGHNEVVEYDCN 238
Cdd:PHA02639  38 EKYEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWSNKAPFC--MLKECNDPPSIINGKIYN-KREMYKVGDEIYYVCN 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  239 PN----FIINGPKKIQCV-DGEWTTLPTCVEQVkTCGYiPELEYGYVQ--PSVPPYQHGVSVEVNCRNEYAMIGNNMITC 311
Cdd:PHA02639 115 EHkgvqYSLVGNEKITCIqDKSWKPDPPICKMI-NCRF-PALQNGYINgiPSNKKFYYKTRVGFSCKSGFDLVGEKYSTC 192

                        170
                 ....*....|....
gi 13540563  312 -INGIW-TELPMCV 323
Cdd:PHA02639 193 nINATWfPSIPTCV 206
PHA02831 PHA02831
EEV host range protein; Provisional
 347-504 1.05e-08

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 56.54  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  347 KEFNHNSRIRYRCSDIFRYRHSVCINGKWNPEVDCTEKREqfCPPPPQIPNAQNMTTTVNYQDGEKVAVLCK----ENYL 422
Cdd:PHA02831  38 KVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKRN--CKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYS 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  423 LPEAKEIVCKDGRWQ------SLPRCvestaycgPPPSINNGDTTSFPLSVYpPGSTVTYRCQSFYKLQGSVTVTCR-NK 495
Cdd:PHA02831 116 IVGNETVKCINKQWVpkypvcKLIRC--------KYPALQNGFLNVFEKKFY-YGDIVNFKCKKGFILLGSSVSTCDiNS 186

                        170
                 ....*....|
gi 13540563  496 QW-SEPPRCL 504
Cdd:PHA02831 187 IWyPGIPKCV 196
PHA02831 PHA02831
EEV host range protein; Provisional
 227-379 1.17e-08

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 56.54  E-value: 1.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  227 YGHNEVVEYDCNPNFiinGPKKIQCVDGEWTTLPTCVEQvKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCR----NEYA 302
Cdd:PHA02831  40 YEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIGK-RNCKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYS 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  303 MIGNNMITCINGIWT-ELPMCvathQLKRCKIAGVNiKTLLKLSGKEFNHNSRIRYRCSDIFRYRHSVC----INGKWNP 377
Cdd:PHA02831 116 IVGNETVKCINKQWVpKYPVC----KLIRCKYPALQ-NGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVstcdINSIWYP 190


                 ..
gi 13540563  378 EV 379
Cdd:PHA02831 191 GI 192
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 147-202 3.99e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.77  E-value: 3.99e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563 147 CHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTCK 202
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGgWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 449-503 5.14e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 5.14e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563    449 CGPPPSINNGDTTSFPlSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 503
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
449-503 1.51e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.51e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563   449 CGPPPSINNGDTTSfPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 503
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 208-262 2.69e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 2.69e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563    208 CGPPPQLSNGEVKeIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTC 262
Cdd:smart00032   1 CPPPPDIENGTVT-SSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 274-390 5.02e-07

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 51.63  E-value: 5.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  274 ELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCINGIWTELPMCvathqLKRCKIAGVNIKTllkLSGKEFNHNS 353
Cdd:PHA02954 134 QLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYISCTANSWNVIPSC-----QQKCDIPSLSNGL---ISGSTFSIGG 205

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 13540563  354 RIRYRCSDIFRYR---HSVCINGKWNPEVD-CTEKREQFCP 390
Cdd:PHA02954 206 VIHLSCKSGFTLTgspSSTCIDGKWNPVLPiCVRSNEEFDP 246
Sushi pfam00084
Sushi repeat (SCR repeat);
389-442 7.04e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.34  E-value: 7.04e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 13540563   389 CPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVC-KDGRWQSL-PRC 442
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 147-201 9.64e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 9.64e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 13540563    147 CHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTC 201
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGtWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 107-263 1.31e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.43  E-value: 1.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  107 GDTVQIICNTGYSLQNNEKNISCVERG---WST-PPICSFTkgECHVPILEANVDAQPKKESYKVGDVLKFSCRKN---- 178
Cdd:PHA02639  43 GKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSNkAPFCMLK--ECNDPPSIINGKIYNKREMYKVGDEIYYVCNEHkgvq 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  179 LIRVGSDSVQCYQ-FGWSPNFPTCKgqVRSCgPPPQLSNGEVKEI-RKEEYGHNEVVEYDCNPNFIINGPKKIQC-VDGE 255
Cdd:PHA02639 121 YSLVGNEKITCIQdKSWKPDPPICK--MINC-RFPALQNGYINGIpSNKKFYYKTRVGFSCKSGFDLVGEKYSTCnINAT 197


                 ....*....
gi 13540563  256 W-TTLPTCV 263
Cdd:PHA02639 198 WfPSIPTCV 206
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 269-322 1.33e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.60  E-value: 1.33e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 13540563    269 CGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCI-NGIWT-ELPMC 322
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 208-379 1.42e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.43  E-value: 1.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  208 CGPPPQLSNGEVKEIRkEEYGHNEVVEYDCNPNFIINGPKKIQCV----DGEWTT-LPTCVeqVKTCGYIPELEYGYVQP 282
Cdd:PHA02639  22 CDKPDDISNGFITELM-EKYEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSNkAPFCM--LKECNDPPSIINGKIYN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  283 SVPPYQHGVSVEVNCRN----EYAMIGNNMITCI-NGIWT-ELPMCvathQLKRCKIAGVNIKTLLKL-SGKEFNHNSRI 355
Cdd:PHA02639  99 KREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIqDKSWKpDPPIC----KMINCRFPALQNGYINGIpSNKKFYYKTRV 174

                        170       180
                 ....*....|....*....|....*...
gi 13540563  356 RYRCS---DIFRYRHSVC-INGKWNPEV 379
Cdd:PHA02639 175 GFSCKsgfDLVGEKYSTCnINATWFPSI 202
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 269-323 2.47e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.76  E-value: 2.47e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563 269 CGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCI-NGIWT-ELPMCV 323
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
208-262 9.49e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.26  E-value: 9.49e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563   208 CGPPPQLSNGEVkEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTC 262
Cdd:pfam00084   1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 389-443 9.88e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.22  E-value: 9.88e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563 389 CPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVC-KDGRW-QSLPRCV 443
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWsPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 196-323 9.96e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.86  E-value: 9.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  196 PNFPTCKGQVRSCGPPPQLSNGEVKEiRKEEYGHNEVVEYDCNPN-----FIINGPKKIQC-VDGEWTTLPTCVEQVKtC 269
Cdd:PHA02817  12 CNKVYSLCDLNKCCYPPSIKNGYIYN-KKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICeKDGKWNKEFPVCKIIR-C 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 13540563  270 GYiPELEYGYVQ--PSVPPYQHGVSVEVNCRNEYAMIGNNMITC-INGIW-TELPMCV 323
Cdd:PHA02817  90 RF-PALQNGFVNgiPDSKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWiPKVPICS 146
PHA02817 PHA02817
EEV Host range protein; Provisional
 140-272 1.58e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.47  E-value: 1.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  140 CSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLI-----RVGSDSVQCYQFG-WSPNFPTCKgqVRSCgPPPQ 213
Cdd:PHA02817  17 SLCDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRgvrytLVGEKNIICEKDGkWNKEFPVCK--IIRC-RFPA 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 13540563  214 LSNGEVKEI-RKEEYGHNEVVEYDCNPNFIINGPKKIQC-VDGEW-TTLPTCVEQVKTCGYI 272
Cdd:PHA02817  94 LQNGFVNGIpDSKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWiPKVPICSRDNITYNKI 155
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 389-442 1.93e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.13  E-value: 1.93e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 13540563    389 CPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVC-KDGRW-QSLPRC 442
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWsPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 352-515 4.48e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 45.85  E-value: 4.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  352 NSRIRYRCSDIFRYRHSVCINGK--WNPEVDCTEKREQfcppPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEI 429
Cdd:PHA02954  94 NSTITLICKDETKYFRCEEKNGNtsWNDTVTCPNAECQ----PLQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYI 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  430 VCKDGRWQSLPRCVESTAYcgppPSINNGDTTSFPLSVyppGSTVTYRCQSFYKLQGSVTVTCRNKQWSEpprCLDPCVV 509
Cdd:PHA02954 170 SCTANSWNVIPSCQQKCDI----PSLSNGLISGSTFSI---GGVIHLSCKSGFTLTGSPSSTCIDGKWNP---VLPICVR 239


                 ....*.
gi 13540563  510 SEENMN 515
Cdd:PHA02954 240 SNEEFD 245
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 87-140 6.77e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.83  E-value: 6.77e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563  87 CSFP-FVKNGHSESSGLIHLEGDTVQIICNTGYSLQNNEKnISCVERG-WS-TPPIC 140
Cdd:cd00033   1 CPPPpVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSST-ITCTENGgWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 269-445 1.74e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 40.80  E-value: 1.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  269 CGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCI----NGIWT-ELPMCVathqLKRCKIAGVNIKTLLK 343
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSnKAPFCM----LKECNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563  344 LSGKEFNHNSRIRYRCSDIFRYRHSVCINGKwnpeVDCTEKReQFCPPPP-------QIPNAQN-----MTTTVNYQDGE 411
Cdd:PHA02639  98 NKREMYKVGDEIYYVCNEHKGVQYSLVGNEK----ITCIQDK-SWKPDPPickmincRFPALQNgyingIPSNKKFYYKT 172

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 13540563  412 KVAVLCKENYLLPEAKEIVCK-DGRW-QSLPRCVES 445
Cdd:PHA02639 173 RVGFSCKSGFDLVGEKYSTCNiNATWfPSIPTCVRN 208
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 11-146 2.00e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.45  E-value: 2.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13540563   11 SWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFsqvptGEVFYYSCEYNFVSPSKSFwtrITCTEEGWSPTPKCLRMCSFP 90
Cdd:PHA02954 118 SWNDTVTCPNAECQPLQLEHGSCQPVKEKYSF-----GEHITINCDVGYEVIGASY---ISCTANSWNVIPSCQQKCDIP 189

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563   91 FVKNGHseSSGLIHLEGDTVQIICNTGYSLQNNEKNiSCVERGWS-TPPICSFTKGE 146
Cdd:PHA02954 190 SLSNGL--ISGSTFSIGGVIHLSCKSGFTLTGSPSS-TCIDGKWNpVLPICVRSNEE 243
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 87-140 2.56e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.35  E-value: 2.56e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 13540563     87 CSFP-FVKNGHSESSGLIHLEGDTVQIICNTGYSLQNNEkNISCVERG-WS-TPPIC 140
Cdd:smart00032   1 CPPPpDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSS-TITCLENGtWSpPPPTC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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