NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|118766350|ref|NP_112187|]
View 

calcium-binding protein 39-like [Homo sapiens]

Protein Classification

Mo25 family protein( domain architecture ID 10554124)

Mo25 family protein has pivotal functions in a signaling pathway that governs cell proliferation and polarity in animals, yeasts, filamentous fungi and plants.

Gene Ontology:  GO:0035556|GO:0030295

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Mo25 pfam08569
Mo25-like; Mo25-like proteins are involved in both polarised growth and cytokinesis. In ...
6-333 0e+00

Mo25-like; Mo25-like proteins are involved in both polarised growth and cytokinesis. In fission yeast Mo25 is localized alternately to the spindle pole body and to the site cell division in a cell cycle dependent manner.


:

Pssm-ID: 462522  Cd Length: 331  Bit Score: 525.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350    6 LFSKSHKNPAEIVKILKDNLAILEKQ--DKKTDKASEEVSKSLQAMKEILCGTNEKEPPTEAVAQLAQELYSSGLLVTLI 83
Cdd:pfam08569   2 LFKKRPKTPAELVKALRELLSKLDSSsdSDNKKKAQEELSKYLSQMKEILYGTGETEPQPEQVAQLAQEIYNEDLLYLLV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350   84 ADLQLIDFEGKKDVTQIFNNILRRQIGTRSPTVEYISAHPHILFMLLKGYEAPQIALRCGIMLRECIRHEPLAKIILFSN 163
Cdd:pfam08569  82 VNLPKLDFEARKDVAQIFSNLLRRQVGSRLPTVDYLVNHPEILDLLLKGYENPDIALNCGNILRECIKHEALAKIILYSP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350  164 QFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIFEDYEKLLQSENYVTKRQSLKLLGELILDRHNFA 243
Cdd:pfam08569 162 QFWKFFDYVQLPNFEIASDAFATFKELLTRHKKLVAEFLEKNYDRFFEYYNKLLQSGNYVTKRQSLKLLGELLLDRSNYQ 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350  244 IMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKN 323
Cdd:pfam08569 242 VMTRYISSPENLKLIMNLLRDKSKNIQFEAFHVFKVFVANPNKPPPILDILIKNREKLLRFLEDFHTDRTEDEQFEDEKA 321
                         330
                  ....*....|
gi 118766350  324 YLIKQIRDLK 333
Cdd:pfam08569 322 FLIKQIESLP 331
 
Name Accession Description Interval E-value
Mo25 pfam08569
Mo25-like; Mo25-like proteins are involved in both polarised growth and cytokinesis. In ...
6-333 0e+00

Mo25-like; Mo25-like proteins are involved in both polarised growth and cytokinesis. In fission yeast Mo25 is localized alternately to the spindle pole body and to the site cell division in a cell cycle dependent manner.


Pssm-ID: 462522  Cd Length: 331  Bit Score: 525.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350    6 LFSKSHKNPAEIVKILKDNLAILEKQ--DKKTDKASEEVSKSLQAMKEILCGTNEKEPPTEAVAQLAQELYSSGLLVTLI 83
Cdd:pfam08569   2 LFKKRPKTPAELVKALRELLSKLDSSsdSDNKKKAQEELSKYLSQMKEILYGTGETEPQPEQVAQLAQEIYNEDLLYLLV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350   84 ADLQLIDFEGKKDVTQIFNNILRRQIGTRSPTVEYISAHPHILFMLLKGYEAPQIALRCGIMLRECIRHEPLAKIILFSN 163
Cdd:pfam08569  82 VNLPKLDFEARKDVAQIFSNLLRRQVGSRLPTVDYLVNHPEILDLLLKGYENPDIALNCGNILRECIKHEALAKIILYSP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350  164 QFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIFEDYEKLLQSENYVTKRQSLKLLGELILDRHNFA 243
Cdd:pfam08569 162 QFWKFFDYVQLPNFEIASDAFATFKELLTRHKKLVAEFLEKNYDRFFEYYNKLLQSGNYVTKRQSLKLLGELLLDRSNYQ 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350  244 IMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKN 323
Cdd:pfam08569 242 VMTRYISSPENLKLIMNLLRDKSKNIQFEAFHVFKVFVANPNKPPPILDILIKNREKLLRFLEDFHTDRTEDEQFEDEKA 321
                         330
                  ....*....|
gi 118766350  324 YLIKQIRDLK 333
Cdd:pfam08569 322 FLIKQIESLP 331
 
Name Accession Description Interval E-value
Mo25 pfam08569
Mo25-like; Mo25-like proteins are involved in both polarised growth and cytokinesis. In ...
6-333 0e+00

Mo25-like; Mo25-like proteins are involved in both polarised growth and cytokinesis. In fission yeast Mo25 is localized alternately to the spindle pole body and to the site cell division in a cell cycle dependent manner.


Pssm-ID: 462522  Cd Length: 331  Bit Score: 525.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350    6 LFSKSHKNPAEIVKILKDNLAILEKQ--DKKTDKASEEVSKSLQAMKEILCGTNEKEPPTEAVAQLAQELYSSGLLVTLI 83
Cdd:pfam08569   2 LFKKRPKTPAELVKALRELLSKLDSSsdSDNKKKAQEELSKYLSQMKEILYGTGETEPQPEQVAQLAQEIYNEDLLYLLV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350   84 ADLQLIDFEGKKDVTQIFNNILRRQIGTRSPTVEYISAHPHILFMLLKGYEAPQIALRCGIMLRECIRHEPLAKIILFSN 163
Cdd:pfam08569  82 VNLPKLDFEARKDVAQIFSNLLRRQVGSRLPTVDYLVNHPEILDLLLKGYENPDIALNCGNILRECIKHEALAKIILYSP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350  164 QFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIFEDYEKLLQSENYVTKRQSLKLLGELILDRHNFA 243
Cdd:pfam08569 162 QFWKFFDYVQLPNFEIASDAFATFKELLTRHKKLVAEFLEKNYDRFFEYYNKLLQSGNYVTKRQSLKLLGELLLDRSNYQ 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118766350  244 IMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKN 323
Cdd:pfam08569 242 VMTRYISSPENLKLIMNLLRDKSKNIQFEAFHVFKVFVANPNKPPPILDILIKNREKLLRFLEDFHTDRTEDEQFEDEKA 321
                         330
                  ....*....|
gi 118766350  324 YLIKQIRDLK 333
Cdd:pfam08569 322 FLIKQIESLP 331
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH