NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1578-2174

5.44e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 101.55 E-value: 5.44e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1578 HRKRARAEKKRAQEERKLAQEEEKLAQEERQLA--QEERKLAQAYVKITQDDRE---------MAQAEGKFAQKEETLAQ 1646
Cdd:COG1196   171 KERKEEAERKLEATEENLERLEDILGELERQLEplERQAEKAERYRELKEELKEleaellllkLRELEAELEELEAELEE 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1647 RGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEEL-PQREQNLDWQEkelaqeleelewDM 1725
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIaRLEERRRELEE------------RL 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1726 EELSWKEEELNQEEGKLveekkklaeeeealawqREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL 1805
Cdd:COG1196   319 EELEEELAELEEELEEL-----------------EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1806 IEKKMKLAQKRErwinsmeeltknkmilyQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLgmfN 1885
Cdd:COG1196   382 EELAEELLEALR-----------------AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE---E 441

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1886 KILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAM-------VQGKKRLRGELDIAK 1958
Cdd:COG1196   442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAeadyegfLEGVKAALLLAGLRG 521

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1959 EEKALNLEmkRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEF 2038
Cdd:COG1196   522 LAGAVAVL--IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2039 TRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKL 2118
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775 2119 DIKewdfsEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV 2174
Cdd:COG1196   680 ELE-----ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1414-2286

2.70e-19

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 96.19 E-value: 2.70e-19

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1414 GKIKR-EMTKEERdMSEEVEEMATLEEKVVKQEGKLVMIERTPSwqdwkkawdewkqvhgETRKSWKAWKEEWEKRLLQE 1492
Cdd:pfam02463  142 GKIEIiAMMKPER-RLEIEEEAAGSRLKRKKKEALKKLIEETEN----------------LAELIIDLEELKLQELKLKE 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1493 EEKLHQAGEKLSPEEEMLQEDKKLKWEEW-KQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Cdd:pfam02463  205 QAKKALEYYQLKEKLELEEEYLLYLDYLKlNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQ 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1572 HKW-ARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ---KEETLAQR 1647
Cdd:pfam02463  285 EEElKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAeeeEEEELEKL 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1648 GEKLSQEAEKLAQKRKKLAKKWEKVAREEEK---LAKKGGKLAEVKNILAQKVEELPQREQNldwqEKELAQELEELEWD 1724
Cdd:pfam02463  365 QEKLEQLEEELLAKKKLESERLSSAAKLKEEeleLKSEEEKEAQLLLELARQLEDLLKEEKK----EELEILEEEEESIE 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1725 MEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQ 1804
Cdd:pfam02463  441 LKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1805 LIEKKMKlAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMF 1884
Cdd:pfam02463  521 GGRIISA-HGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1885 NKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKE--EKA 1962
Cdd:pfam02463  600 DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKEllEIQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1963 LNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQ 2042
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2043 RIFVQGqrklaKASRKLIKKRESLSKEPAKLNKilKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKE 2122
Cdd:pfam02463  760 EEKEEE-----KSELSLKEKELAEEREKTEKLK--VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKE 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2123 WDFSEKRseltkDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE 2202
Cdd:pfam02463  833 EELEELA-----LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQ 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2203 AKRG--DKPKEKFSSQVDEVESEEHFSEEMESLLDE----------LEKQESLSSEEEEEREEEEEREEEEEREEEEERK 2270
Cdd:pfam02463  908 KLNLleEKENEIEERIKEEAEILLKYEEEPEELLLEeadekekeenNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE 987

                          890
                   ....*....|....*.
gi 597709775  2271 EEEEGEEKQVEKEEEE 2286
Cdd:pfam02463  988 ERYNKDELEKERLEEE 1003

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1558-2237

2.12e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 83.18 E-value: 2.12e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1558 EQQVTEEQRHIQE-EHKWARIHRKRARAEKK--RAQEERKLAQEEEKLAQEERQLAQEERKlaqayvkitqddremaQAE 1634
Cdd:TIGR02168  252 EEELEELTAELQElEEKLEELRLEVSELEEEieELQKELYALANEISRLEQQKQILRERLA----------------NLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1635 GKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELpqreqnldwqekel 1714
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL-------------- 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1715 aqeleelewdmEELSWKEEELNQEEGKLVEekkklaeeeealawQREKLSEEETKLAQEEELLIQEKEKLAQHKE--KMP 1792
Cdd:TIGR02168  382 -----------ETLRSKVAQLELQIASLNN--------------EIERLEARLERLEDRRERLQQEIEELLKKLEeaELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1793 EEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKK 1872
Cdd:TIGR02168  437 ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1873 QLVQVKNKLGMfnkiLAQVEEKLTQEKETVikkkekLAETEKKLVQVEDSLAKK-QEKLAQEKMKLA------------L 1939
Cdd:TIGR02168  517 GLSGILGVLSE----LISVDEGYEAAIEAA------LGGRLQAVVVENLNAAKKaIAFLKQNELGRVtflpldsikgteI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1940 EKAMVQGKKRLRGELDIAKE--------EKALN---------------LEMKRLAEEKMRLVEGKETL-----------S 1985
Cdd:TIGR02168  587 QGNDREILKNIEGFLGVAKDlvkfdpklRKALSyllggvlvvddldnaLELAKKLRPGYRIVTLDGDLvrpggvitggsA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1986 KGETPETSRQRKMTQVEQELFERKLSLEE-----KILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLI 2060
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAElekalAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2061 KKRESLSKEPAKLN--------KILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSEL 2132
Cdd:TIGR02168  747 ERIAQLSKELTELEaeieeleeRLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2133 TKDEKKLARKQRKLANKMRRMINKEEKMteEESKLARKHSEVILDDEEEGGIEeeevipFLKRRWRKRKEAKRGDKPKEK 2212
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDI--ESLAAEIEELEELIEELESELEA------LLNERASLEEALALLRSELEE 898

                          730       740
                   ....*....|....*....|....*
gi 597709775  2213 FSSQVDEVESEEHfseEMESLLDEL 2237
Cdd:TIGR02168  899 LSEELRELESKRS---ELRRELEEL 920

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

213-492

1.15e-11

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 68.13 E-value: 1.15e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  213 DQGFLYAGNQAGEIQVWSLQQGHPLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWNLTSGSLLRRLElG--EELYR 290
Cdd:cd00200    20 DGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLT-GhtSYVSS 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  291 LQFIDSITFFC-----QTAHSFSLHRLPCFYSLfnvcgsaPQQLRRVCC----GNNWFrILCTTEDGLLRFVSPVTGdLL 361
Cdd:cd00200    99 VAFSPDGRILSsssrdKTIKVWDVETGKCLTTL-------RGHTDWVNSvafsPDGTF-VASSSQDGTIKLWDLRTG-KC 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  362 VITwpFSILDQAVDW-AYDPGKEELFVATGSSEVLVFDTTrcpcpAKYLLGTSPNSQDFVQCLAYGHFNLgrglegLIFS 440
Cdd:cd00200   170 VAT--LTGHTGEVNSvAFSPDGEKLLSSSSDGTIKLWDLS-----TGKCLGTLRGHENGVNSVAFSPDGY------LLAS 236

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 597709775  441 GHQSGVIRVLSQHSCARLEKF-MHFGAVLALSTLSGGIFggqgnslLCSYGMD 492
Cdd:cd00200   237 GSEDGTIRVWDLRTGECVQTLsGHTNSVTSLAWSPDGKR-------LASGSAD 282

WD40

COG2319

WD40 repeat [General function prediction only];

213-598

2.13e-11

WD40 repeat [General function prediction only];

Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 68.78 E-value: 2.13e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  213 DQGFLYAGNQAGEIQVWSLQQGHPLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWNLTSGSLLRRLELGEElyrlq 292
Cdd:COG2319    89 DGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSG----- 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  293 FIDSITFfcqtahsfslhrlpcfyslfnvcgSAPQQlrrvccgnnwfRILCTTEDGLLRFVSPVTGDLLvitWPFSILDQ 372
Cdd:COG2319   164 AVTSVAF------------------------SPDGK-----------LLASGSDDGTVRLWDLATGKLL---RTLTGHTG 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  373 AV-DWAYDP-GKeelFVATGSS--EVLVFDTTRCPCpakylLGTSPNSQDFVQCLAY---GHfnlgrglegLIFSGHQSG 445
Cdd:COG2319   206 AVrSVAFSPdGK---LLASGSAdgTVRLWDLATGKL-----LRTLTGHSGSVRSVAFspdGR---------LLASGSADG 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  446 VIRV--LSQHSCARLEKfMHFGAVLALStlsggiFGGQGNSLLcSYGMDDYVHL----SEAVLDGVKVQLRPLASILSSc 519
Cdd:COG2319   269 TVRLwdLATGELLRTLT-GHSGGVNSVA------FSPDGKLLA-SGSDDGTVRLwdlaTGKLLRTLTGHTGAVRSVAFS- 339

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  520 hlthlillP--KSVGAITETNCLRLWkfhdflssgSQNGLKFIETLPLHLCAITSfdVCLSL--SLFVTGSADGSVRIWD 595
Cdd:COG2319   340 --------PdgKTLASGSDDGTVRLW---------DLATGELLRTLTGHTGAVTS--VAFSPdgRTLASGSADGTVRLWD 400


                  ...
gi 597709775  596 FHG 598
Cdd:COG2319   401 LAT 403

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

373-635

7.09e-07

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 53.49 E-value: 7.09e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  373 AVDWAYDPGkeelFVATGSS--EVLVFDTTRCPCPAKYLLGTSPnsqdFVQCLAYGHFNLgrgleglIFSGHQSGVIRVL 450
Cdd:cd00200    14 CVAFSPDGK----LLATGSGdgTIKVWDLETGELLRTLKGHTGP----VRDVAASADGTY-------LASGSSDKTIRLW 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  451 SQHSCARLEKF-MHFGAVLALSTLsggifggQGNSLLCSyGMDDYVHLSEAVLDGVKVQLRPlasilssCHLthlillpK 529
Cdd:cd00200    79 DLETGECVRTLtGHTSYVSSVAFS-------PDGRILSS-SSRDKTIKVWDVETGKCLTTLR-------GHT-------D 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  530 SVgaitetNCLRLWKFHDFLSSGSQNG---------LKFIETLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWDFH-GR 599
Cdd:cd00200   137 WV------NSVAFSPDGTFVASSSQDGtiklwdlrtGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLStGK 210

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 597709775  600 LIGILDSslHFGPVCFandrgdllVTFNQSLYLVSC 635
Cdd:cd00200   211 CLGTLRG--HENGVNS--------VAFSPDGYLLAS 236

WD40

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...

558-595

1.95e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.

Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 43.84 E-value: 1.95e-05

                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 597709775    558 KFIETLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWD 595
Cdd:smart00320    3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40

WD40

pfam00400

WD domain, G-beta repeat;

558-595

1.70e-04

WD domain, G-beta repeat;

Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 41.18 E-value: 1.70e-04

                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 597709775   558 KFIETLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWD 595
Cdd:pfam00400    2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39

WD40

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...

233-272

1.98e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.

Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.76 E-value: 1.98e-04

                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 597709775    233 QGHPLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWN 272
Cdd:smart00320    1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40

PRK12704

phosphodiesterase; Provisional

2073-2174

2.30e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 2.30e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2073 LNKILKALQKLTRDERKLTQEEIKM---TKMKRALF-VKERrlsIEQSKLDIkEWDFSEKRSELTKDEKKLARKQRKLAN 2148
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRILEEAKKeaeAIKKEALLeAKEE---IHKLRNEF-EKELRERRNELQKLEKRLLQKEENLDR 100

                          90       100
                  ....*....|....*....|....*.
gi 597709775 2149 KMRRMINKEEKMTEEESKLARKHSEV 2174
Cdd:PRK12704  101 KLELLEKREEELEKKEKELEQKQQEL 126

Spc7

smart00787

Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...

1804-1975

2.37e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.

Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 42.70 E-value: 2.37e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775   1804 QLIEKKMKLA------QKRERWINSMEELTKN-KMILYQKKN-LAQEKKNLAQEKEKLAQRKENLlynKERLTHSKKQLV 1875
Cdd:smart00787  113 LLMDKQFQLVktfarlEAKKMWYEWRMKLLEGlKEGLDENLEgLKEDYKLLMKELELLNSIKPKL---RDRKDALEEELR 189

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775   1876 QVKNKLGMFNKI----LAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLakkqEKLAQEKMKLALEKAMVQgKKRLR 1951
Cdd:smart00787  190 QLKQLEDELEDCdpteLDRAKEKLKKLLQEIMIKVKKLEELEEELQELESKI----EDLTNKKSELNTEIAEAE-KKLEQ 264

                           170       180
                    ....*....|....*....|....
gi 597709775   1952 GELDIAKEEKALNLEMKRLAEEKM 1975
Cdd:smart00787  265 CRGFTFKEIEKLKEQLKLLQSLTG 288

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

1558-1661

3.89e-03

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.18 E-value: 3.89e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1558 EQQVTEEQRHIQEEHkwarihRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Cdd:cd16269   190 DQALTEKEKEIEAER------AKAEAAEQERKLLEEQQRELEQKLEDQERSYEEHLRQLKEKMEEERENLLKEQERALES 263

                          90       100
                  ....*....|....*....|....
gi 597709775 1638 AQKEETLAQRgEKLSQEAEKLAQK 1661
Cdd:cd16269   264 KLKEQEALLE-EGFKEQAELLQEE 286

Name

Accession

Description

Interval

E-value

PTZ00121

MAEBL; Provisional

1345-2117

2.24e-24

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 113.31 E-value: 2.24e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1345 REEEQAQKKARDMLGLEETqvilKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAvQKERKVGKIKREMTKEE 1424
Cdd:PTZ00121 1115 RKAEEAKKKAEDARKAEEA----RKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKA-EDAKKAEAARKAEEVRK 1189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1425 RDMSEEVEEMATLEEKVVKQEGKlvMIERTPSWQDWKKAwDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLS 1504
Cdd:PTZ00121 1190 AEELRKAEDARKAEAARKAEEER--KAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFA 1266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1505 PEEEMLQEDKKLKWEEWKqvwenmlssKSKEQQYKDEEEVTLEEEVSREGEEKeqqvTEEQRHIQEEHKWARIHRKRARA 1584
Cdd:PTZ00121 1267 RRQAAIKAEEARKADELK---------KAEEKKKADEAKKAEEKKKADEAKKK----AEEAKKADEAKKKAEEAKKKADA 1333

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ---KEETLAQRGEKLSQEAEKL--- 1658
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEekkKADEAKKKAEEDKKKADELkka 1413

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1659 -AQKRK--KLAKKWEKVAREEE--KLAKKGGKLAEVKNIL--AQKVEELPQREQNldwqekelaqeleelEWDMEELSWK 1731
Cdd:PTZ00121 1414 aAAKKKadEAKKKAEEKKKADEakKKAEEAKKADEAKKKAeeAKKAEEAKKKAEE---------------AKKADEAKKK 1478

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1732 EEELNQEEgklveekkklaeeeealawQREKLSEEETKLAQEEELLIQEKEK---LAQHKEKMPEEEERLGRKREQLIEK 1808
Cdd:PTZ00121 1479 AEEAKKAD-------------------EAKKKAEEAKKKADEAKKAAEAKKKadeAKKAEEAKKADEAKKAEEAKKADEA 1539

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1809 KMKLAQKRERWINSMEELTKnkmilyqkknlAQEKKNlAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKIL 1888
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKK-----------AEEKKK-AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1889 AQveEKLTQEKETVIKKKE-KLAETEKKLVQVEDSLAKKQEKLAQE--------KMKLALEKAMVQGKKRLRGELDIAKE 1959
Cdd:PTZ00121 1608 KA--EEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEElkkaeeenKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1960 EKALNLE-MKRLAEEKMRLvegkETLSKGETPEtsrQRKMTQVEQELFERKLSLEEkillhedrilAMEESEIAKGKLEF 2038
Cdd:PTZ00121 1686 DEKKAAEaLKKEAEEAKKA----EELKKKEAEE---KKKAEELKKAEEENKIKAEE----------AKKEAEEDKKKAEE 1748

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2039 TRGQRifvQGQRKLAKASRKLIKKRESLSKEPAKLnkILKALQKLTRDERKLTQEEIKMTKMKRALFV---KERRLSIEQ 2115
Cdd:PTZ00121 1749 AKKDE---EEKKKIAHLKKEEEKKAEEIRKEKEAV--IEEELDEEDEKRRMEVDKKIKDIFDNFANIIeggKEGNLVIND 1823


                  ..
gi 597709775 2116 SK 2117
Cdd:PTZ00121 1824 SK 1825

PTZ00121

MAEBL; Provisional

1557-2237

7.70e-24

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 111.39 E-value: 7.70e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1557 KEQQVTEEQRHIQEEHKwariHRKRARAEKKRAQEERKLAQEEEKLAQEERQlAQEERKLAQAyvKITQDDREMAQAEGK 1636
Cdd:PTZ00121 1088 RADEATEEAFGKAEEAK----KTETGKAEEARKAEEAKKKAEDARKAEEARK-AEDARKAEEA--RKAEDAKRVEIARKA 1160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1637 FAQKEETLAQRGE--KLSQEAEKLAQKRKKL-AKKWEKVAR-EEEKLAKKGGKLAEVKNIL-AQKVEELPQREQnldwqe 1711
Cdd:PTZ00121 1161 EDARKAEEARKAEdaKKAEAARKAEEVRKAEeLRKAEDARKaEAARKAEEERKAEEARKAEdAKKAEAVKKAEE------ 1234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1712 kelaqeleeLEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQ-REKLSEEETKLAQE----EELLIQEKEKLAQ 1786
Cdd:PTZ00121 1235 ---------AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKaEEARKADELKKAEEkkkaDEAKKAEEKKKAD 1305

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1787 HKEKMPEEEerlgRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENllYNKER 1866
Cdd:PTZ00121 1306 EAKKKAEEA----KKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE--EAKKK 1379

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1867 LTHSKKQLVQVKNKLGMFNKilAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDslAKKQEKLAQEKMKLALEKAMVQG 1946
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADEAKKK--AEEDKKKADELKKAAAAKKKADEAKKKAEEKKK--ADEAKKKAEEAKKADEAKKKAEE 1455

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1947 KKRLRgELDIAKEEKALNLEMKRLAEEKMRLVEGK----ETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDR 2022
Cdd:PTZ00121 1456 AKKAE-EAKKKAEEAKKADEAKKKAEEAKKADEAKkkaeEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK 1534

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2023 ilameESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNK--ILKALQKLTRDERKLTQEEIKMTKM 2100
Cdd:PTZ00121 1535 -----KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKaeEAKKAEEARIEEVMKLYEEEKKMKA 1609

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2101 KRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKlANKMRRMINKEEKMTEEESKlaRKHSEVILDDEE 2180
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKK-AEEENKIKAAEEAKKAEEDK--KKAEEAKKAEED 1686

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 597709775 2181 EGGIEeeevipflKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDEL 2237
Cdd:PTZ00121 1687 EKKAA--------EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEA 1735

PRK03918

DNA double-strand break repair ATPase Rad50;

1670-2219

5.27e-21

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 101.29 E-value: 5.27e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1670 EKVAREE---EKLAKKGGKLAEVKNILAQKVEELP---QREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLV 1743
Cdd:PRK03918  148 EKVVRQIlglDDYENAYKNLGEVIKEIKRRIERLEkfiKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1744 EEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGR--KREQLIEKKMKLAQKRERWIN 1821
Cdd:PRK03918  228 KEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElkELKEKAEEYIKLSEFYEEYLD 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1822 SMEELTKNKMILYQKKNLAQEK----KNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVE----E 1893
Cdd:PRK03918  308 ELREIEKRLSRLEEEINGIEERikelEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTgltpE 387

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1894 KLTQEKETVIKKKEKLAETEKKLVQVEDSLAK--KQEKLAQEKMKLALEKAMVQGKkrlrgELDIAKEEKALN---LEMK 1968
Cdd:PRK03918  388 KLEKELEELEKAKEEIEEEISKITARIGELKKeiKELKKAIEELKKAKGKCPVCGR-----ELTEEHRKELLEeytAELK 462

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1969 RLAEEKMRLVEGKETLSKGETP---ETSRQRKMTqVEQELFERKLSLEEKILLH--EDRILAMEESEIAKGKLEFTRGQR 2043
Cdd:PRK03918  463 RIEKELKEIEEKERKLRKELRElekVLKKESELI-KLKELAEQLKELEEKLKKYnlEELEKKAEEYEKLKEKLIKLKGEI 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2044 IFVQGQRK----LAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDE--------RKLTQEEIKMTKMKRALFVKERRL 2111
Cdd:PRK03918  542 KSLKKELEkleeLKKKLAELEKKLDELEEELAELLKELEELGFESVEEleerlkelEPFYNEYLELKDAEKELEREEKEL 621

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2112 SIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRmiNKEEKMTEEESKLARKHSEviLDDEEEGGIEEEEVIP 2191
Cdd:PRK03918  622 KKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYE--ELREEYLELSRELAGLRAE--LEELEKRREEIKKTLE 697

                         570       580
                  ....*....|....*....|....*...
gi 597709775 2192 FLKRRWRKRKEAKRGDKPKEKFSSQVDE 2219
Cdd:PRK03918  698 KLKEELEEREKAKKELEKLEKALERVEE 725

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1578-2174

5.44e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 101.55 E-value: 5.44e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1578 HRKRARAEKKRAQEERKLAQEEEKLAQEERQLA--QEERKLAQAYVKITQDDRE---------MAQAEGKFAQKEETLAQ 1646
Cdd:COG1196   171 KERKEEAERKLEATEENLERLEDILGELERQLEplERQAEKAERYRELKEELKEleaellllkLRELEAELEELEAELEE 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1647 RGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEEL-PQREQNLDWQEkelaqeleelewDM 1725
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIaRLEERRRELEE------------RL 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1726 EELSWKEEELNQEEGKLveekkklaeeeealawqREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL 1805
Cdd:COG1196   319 EELEEELAELEEELEEL-----------------EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1806 IEKKMKLAQKRErwinsmeeltknkmilyQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLgmfN 1885
Cdd:COG1196   382 EELAEELLEALR-----------------AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE---E 441

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1886 KILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAM-------VQGKKRLRGELDIAK 1958
Cdd:COG1196   442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAeadyegfLEGVKAALLLAGLRG 521

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1959 EEKALNLEmkRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEF 2038
Cdd:COG1196   522 LAGAVAVL--IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2039 TRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKL 2118
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775 2119 DIKewdfsEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV 2174
Cdd:COG1196   680 ELE-----ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

PTZ00121

MAEBL; Provisional

1401-2293

1.64e-20

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 100.22 E-value: 1.64e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1401 KQGRKAvQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKlvMIERTPSWQDWKKAWDEWKQvhGETRKSWKA 1480
Cdd:PTZ00121 1131 EEARKA-EDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAK--KAEAARKAEEVRKAEELRKA--EDARKAEAA 1205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1481 WKEEWEKRLlqeeEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWE---NMLSSKSKEQQYKDEEEVTLEEEVSREGEEK 1557
Cdd:PTZ00121 1206 RKAEEERKA----EEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEernNEEIRKFEEARMAHFARRQAAIKAEEARKAD 1281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1558 EQQVTEEQRHIQEEHKWARIHR----KRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQA 1633
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKadeaKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1634 EGKFAQKEETLAQRGEKLSQEAEKLAQKRKKlAKKWEKVAREEEKLAKKGGKLAEVKnilaQKVEELPQREQNLdwQEKE 1713
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKK-ADEAKKKAEEDKKKADELKKAAAAK----KKADEAKKKAEEK--KKAD 1434

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1714 LAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPE 1793
Cdd:PTZ00121 1435 EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1794 ----EEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMIlyqKKnlAQEKKNlAQEKEKLAQRKENLLYNKERLTH 1869
Cdd:PTZ00121 1515 akkaEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEL---KK--AEEKKK-AEEAKKAEEDKNMALRKAEEAKK 1588

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1870 SKKQLVQVKNKLGMFNKILAQveEKLTQEKETVIKKKE-KLAETEKKLVQvEDSLAKKQEKLAQEKMKLALEKAMVQgkk 1948
Cdd:PTZ00121 1589 AEEARIEEVMKLYEEEKKMKA--EEAKKAEEAKIKAEElKKAEEEKKKVE-QLKKKEAEEKKKAEELKKAEEENKIK--- 1662

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1949 rlrgeldiAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEkillhedrilAMEE 2028
Cdd:PTZ00121 1663 --------AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE----------LKKA 1724

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2029 SEIAKGKLEftrgqrifvqgqrKLAKASRKLIKKRESLSKEPAKLNKIlkalQKLTRDERKLTQEeikmtkmkralFVKE 2108
Cdd:PTZ00121 1725 EEENKIKAE-------------EAKKEAEEDKKKAEEAKKDEEEKKKI----AHLKKEEEKKAEE-----------IRKE 1776

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2109 RRLSIEQsKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEggieeee 2188
Cdd:PTZ00121 1777 KEAVIEE-ELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADA------- 1848

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2189 vipFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMEslldelekqeslsseeeeerEEEEEREEEEEREEEEE 2268
Cdd:PTZ00121 1849 ---FEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEAD--------------------EIEKIDKDDIEREIPNN 1905

                         890       900
                  ....*....|....*....|....*
gi 597709775 2269 RKEEEEGEEKQVEKEEEEKKKKKKE 2293
Cdd:PTZ00121 1906 NMAGKNNDIIDDKLDKDEYIKRDAE 1930

PTZ00121

MAEBL; Provisional

1334-1829

4.03e-20

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 99.06 E-value: 4.03e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1334 QEVIRHKEVMPREE----EQAQKKARDMLGLEETQVILKKGKKVIflEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQK 1409
Cdd:PTZ00121 1287 EEKKKADEAKKAEEkkkaDEAKKKAEEAKKADEAKKKAEEAKKKA--DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1410 ERKVGKIKREMTKEERD-MSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKR 1488
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADaAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK 1444

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1489 LLQEEEKlhQAGEKLSPEEEMLQEDKKLKWEEWKQVWEnmlsSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHI 1568
Cdd:PTZ00121 1445 KADEAKK--KAEEAKKAEEAKKKAEEAKKADEAKKKAE----EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1569 QEEHKWARIHR----KRA----RAEKKRAQEERKLAQE----EEKLAQEERQLAQEERKLA---------------QAYV 1621
Cdd:PTZ00121 1519 EEAKKADEAKKaeeaKKAdeakKAEEKKKADELKKAEElkkaEEKKKAEEAKKAEEDKNMAlrkaeeakkaeeariEEVM 1598

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1622 KITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLA---KKWEKVAREEEKLAKKGGKLAEVKNILAQKVE 1698
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAeekKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE 1678

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1699 ELPQREQNlDWQEKELAQELEELEWDMEELSWKEEElnqeEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAqeEELLI 1778
Cdd:PTZ00121 1679 EAKKAEED-EKKAAEALKKEAEEAKKAEELKKKEAE----EKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA--EEAKK 1751

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 597709775 1779 Q--EKEKLAQHKEKMPEEEERLGRKREQLIEKKMKlaQKRERWINSMEELTKN 1829
Cdd:PTZ00121 1752 DeeEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD--EEDEKRRMEVDKKIKD 1802

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1579-2153

2.53e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 96.16 E-value: 2.53e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1579 RKRARAEKKRA-QEERKLAQ----------EEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQR 1647
Cdd:COG1196   207 RQAEKAERYRElKEELKELEaellllklreLEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1648 GEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELeelewdmEE 1727
Cdd:COG1196   287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE-------AE 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1728 LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIE 1807
Cdd:COG1196   360 LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1808 KKMKLAQKRERWINSMEELTK-NKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNK 1886
Cdd:COG1196   440 EEEALEEAAEEEAELEEEEEAlLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1887 --------ILAQVEEKLTQEKETVIkkkekLAETEKKLVQVEDSLAKKQEKLAQEKMKLA--LEKAMVQGKKRLRGELDI 1956
Cdd:COG1196   520 rglagavaVLIGVEAAYEAALEAAL-----AAALQNIVVEDDEVAAAAIEYLKAAKAGRAtfLPLDKIRARAALAAALAR 594

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1957 AKEEKALNLEMKRLAEEKMRLVEGKETLSkGETPETSRQRKMTQVEQELFERKLSLEekillhedriLAMEESEIAKGKL 2036
Cdd:COG1196   595 GAIGAAVDLVASDLREADARYYVLGDTLL-GRTLVAARLEAALRRAVTLAGRLREVT----------LEGEGGSAGGSLT 663

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2037 EFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEpAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQS 2116
Cdd:COG1196   664 GGSRRELLAALLEAEAELEELAERLAEEELELE-EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 597709775 2117 KLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRM 2153
Cdd:COG1196   743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1414-2286

2.70e-19

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 96.19 E-value: 2.70e-19

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1414 GKIKR-EMTKEERdMSEEVEEMATLEEKVVKQEGKLVMIERTPSwqdwkkawdewkqvhgETRKSWKAWKEEWEKRLLQE 1492
Cdd:pfam02463  142 GKIEIiAMMKPER-RLEIEEEAAGSRLKRKKKEALKKLIEETEN----------------LAELIIDLEELKLQELKLKE 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1493 EEKLHQAGEKLSPEEEMLQEDKKLKWEEW-KQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Cdd:pfam02463  205 QAKKALEYYQLKEKLELEEEYLLYLDYLKlNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQ 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1572 HKW-ARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ---KEETLAQR 1647
Cdd:pfam02463  285 EEElKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAeeeEEEELEKL 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1648 GEKLSQEAEKLAQKRKKLAKKWEKVAREEEK---LAKKGGKLAEVKNILAQKVEELPQREQNldwqEKELAQELEELEWD 1724
Cdd:pfam02463  365 QEKLEQLEEELLAKKKLESERLSSAAKLKEEeleLKSEEEKEAQLLLELARQLEDLLKEEKK----EELEILEEEEESIE 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1725 MEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQ 1804
Cdd:pfam02463  441 LKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1805 LIEKKMKlAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMF 1884
Cdd:pfam02463  521 GGRIISA-HGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1885 NKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKE--EKA 1962
Cdd:pfam02463  600 DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKEllEIQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1963 LNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQ 2042
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2043 RIFVQGqrklaKASRKLIKKRESLSKEPAKLNKilKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKE 2122
Cdd:pfam02463  760 EEKEEE-----KSELSLKEKELAEEREKTEKLK--VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKE 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2123 WDFSEKRseltkDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE 2202
Cdd:pfam02463  833 EELEELA-----LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQ 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2203 AKRG--DKPKEKFSSQVDEVESEEHFSEEMESLLDE----------LEKQESLSSEEEEEREEEEEREEEEEREEEEERK 2270
Cdd:pfam02463  908 KLNLleEKENEIEERIKEEAEILLKYEEEPEELLLEeadekekeenNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE 987

                          890
                   ....*....|....*.
gi 597709775  2271 EEEEGEEKQVEKEEEE 2286
Cdd:pfam02463  988 ERYNKDELEKERLEEE 1003

PRK03918

DNA double-strand break repair ATPase Rad50;

1585-2127

4.98e-19

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 94.75 E-value: 4.98e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1585 EKKRAQEERKLAQEEE--KLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKR 1662
Cdd:PRK03918  193 ELIKEKEKELEEVLREinEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELK 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1663 KKLAKKWEKVAR--EEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEleelewdMEELSWKEEELNQEEG 1740
Cdd:PRK03918  273 KEIEELEEKVKElkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER-------IKELEEKEERLEELKK 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1741 KLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWI 1820
Cdd:PRK03918  346 KLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELK 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1821 NSMEELTKNK------------------MILYQK--KNLAQEKKNLAQEKEKLAQRK---ENLLYNKERLTHSKK---QL 1874
Cdd:PRK03918  426 KAIEELKKAKgkcpvcgrelteehrkelLEEYTAelKRIEKELKEIEEKERKLRKELrelEKVLKKESELIKLKElaeQL 505

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1875 VQVKNKLGMFNKilaqveEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEklaQEKMKLALEKAMVQGKKRLRGEL 1954
Cdd:PRK03918  506 KELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE---LKKKLAELEKKLDELEEELAELL 576

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1955 DIAKEE-----KALNLEMKRLAEEKMRLVEGKEtlSKGETPETSRQRKMTQVEQELFERKLSLEEKillhedrILAMEES 2029
Cdd:PRK03918  577 KELEELgfesvEELEERLKELEPFYNEYLELKD--AEKELEREEKELKKLEEELDKAFEELAETEK-------RLEELRK 647

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2030 EIAKGKLEFTrgQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRAL-FVKE 2108
Cdd:PRK03918  648 ELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALeRVEE 725

                         570
                  ....*....|....*....
gi 597709775 2109 RRLSIEQSKLDIKEWDFSE 2127
Cdd:PRK03918  726 LREKVKKYKALLKERALSK 744

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1313-2138

9.71e-17

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 87.72 E-value: 9.71e-17

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1313 EKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDmLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEE 1392
Cdd:pfam02463  251 EEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE-EEELKSELLKLERRKVDDEEKLKESEKEKKKAEKE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1393 kktfQKSPKQGRKAVQKERKVGKIKRE-MTKEERDMSEEVEEMATLEEKVVK------QEGKLVMIERTPSWQDWKKAWD 1465
Cdd:pfam02463  330 ----LKKEKEEIEELEKELKELEIKREaEEEEEEELEKLQEKLEQLEEELLAkkklesERLSSAAKLKEEELELKSEEEK 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1466 EWKQVHGETRKSWKAWKEEWEKRLLQEEEKLH-----QAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKS--KEQQY 1538
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEEsielkQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQlvKLQEQ 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1539 KDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQ 1618
Cdd:pfam02463  486 LELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQK 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1619 AYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAReeEKLAKKGGKLAEVKNILAQKVE 1698
Cdd:pfam02463  566 LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR--AKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1699 ELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLI 1778
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1779 QEKEKLAQHKEKmpEEEERLGRKREQLIEKKMKLAQKRERWINSMEELtKNKMILYQKKNLAQEKKNLAQEKEKLAQRKE 1858
Cdd:pfam02463  724 ADRVQEAQDKIN--EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL-SLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1859 NLLYNKERLthskkqlvqvknklgmfNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLA 1938
Cdd:pfam02463  801 EELRALEEE-----------------LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1939 LEKAMVQGKKRLRGELDiakEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILL 2018
Cdd:pfam02463  864 TKEELLQELLLKEEELE---EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL 940

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2019 HEDRILAMEESEIAKGKLEftrgQRIfVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMT 2098
Cdd:pfam02463  941 LLEEADEKEKEENNKEEEE----ERN-KRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEET 1015

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 597709775  2099 KMKralFVKERRLSIEQSKLDIKEW--DFSEKRSELTKDEKK 2138
Cdd:pfam02463 1016 CQR---LKEFLELFVSINKGWNKVFfyLELGGSAELRLEDPD 1054

SMC_N

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

1568-2364

5.96e-16

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 85.02 E-value: 5.96e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1568 IQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQE--ERKLAQAYVKITQDDREMAQAEgKFAQKEETLA 1645
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLkeQAKKALEYYQLKEKLELEEEYL-LYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1646 QRGEKLSQEAEKLAQKRKKLAKKWEKvarEEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDM 1725
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEK---EEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1726 EELSWKEEELNQEEgklveekkklaeeeealawqrEKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL 1805
Cdd:pfam02463  314 EKLKESEKEKKKAE---------------------KELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLE 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1806 IEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKEN-LLYNKERLTHSKKQLVQVKNKLGMF 1884
Cdd:pfam02463  373 EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKeELEILEEEEESIELKQGKLTEEKEE 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1885 NKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVE-DSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKAL 1963
Cdd:pfam02463  453 LEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELlLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLG 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1964 NLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKmtqveqELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQR 2043
Cdd:pfam02463  533 DLGVAVENYKVAISTAVIVEVSATADEVEERQKL------VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLA 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2044 IFVQgqrklAKASRKLIKKREslsKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEW 2123
Cdd:pfam02463  607 QLDK-----ATLEADEDDKRA---KVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEI 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2124 DFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEEsklarkhsEVILDDEEEGGIEEEEVIPFLKRRWRKRKEA 2203
Cdd:pfam02463  679 QELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEA--------EELLADRVQEAQDKINEELKLLKQKIDEEEE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2204 KRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEEREEEEERKEEEEGEEKQVEKE 2283
Cdd:pfam02463  751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKI 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2284 EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGR 2363
Cdd:pfam02463  831 KEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLN 910


                   .
gi 597709775  2364 E 2364
Cdd:pfam02463  911 L 911

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1558-2237

2.12e-15

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 83.18 E-value: 2.12e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1558 EQQVTEEQRHIQE-EHKWARIHRKRARAEKK--RAQEERKLAQEEEKLAQEERQLAQEERKlaqayvkitqddremaQAE 1634
Cdd:TIGR02168  252 EEELEELTAELQElEEKLEELRLEVSELEEEieELQKELYALANEISRLEQQKQILRERLA----------------NLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1635 GKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELpqreqnldwqekel 1714
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL-------------- 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1715 aqeleelewdmEELSWKEEELNQEEGKLVEekkklaeeeealawQREKLSEEETKLAQEEELLIQEKEKLAQHKE--KMP 1792
Cdd:TIGR02168  382 -----------ETLRSKVAQLELQIASLNN--------------EIERLEARLERLEDRRERLQQEIEELLKKLEeaELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1793 EEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKK 1872
Cdd:TIGR02168  437 ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1873 QLVQVKNKLGMfnkiLAQVEEKLTQEKETVikkkekLAETEKKLVQVEDSLAKK-QEKLAQEKMKLA------------L 1939
Cdd:TIGR02168  517 GLSGILGVLSE----LISVDEGYEAAIEAA------LGGRLQAVVVENLNAAKKaIAFLKQNELGRVtflpldsikgteI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1940 EKAMVQGKKRLRGELDIAKE--------EKALN---------------LEMKRLAEEKMRLVEGKETL-----------S 1985
Cdd:TIGR02168  587 QGNDREILKNIEGFLGVAKDlvkfdpklRKALSyllggvlvvddldnaLELAKKLRPGYRIVTLDGDLvrpggvitggsA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1986 KGETPETSRQRKMTQVEQELFERKLSLEE-----KILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLI 2060
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAElekalAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2061 KKRESLSKEPAKLN--------KILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSEL 2132
Cdd:TIGR02168  747 ERIAQLSKELTELEaeieeleeRLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2133 TKDEKKLARKQRKLANKMRRMINKEEKMteEESKLARKHSEVILDDEEEGGIEeeevipFLKRRWRKRKEAKRGDKPKEK 2212
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDI--ESLAAEIEELEELIEELESELEA------LLNERASLEEALALLRSELEE 898

                          730       740
                   ....*....|....*....|....*
gi 597709775  2213 FSSQVDEVESEEHfseEMESLLDEL 2237
Cdd:TIGR02168  899 LSEELRELESKRS---ELRRELEEL 920

sbcc

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1417-2143

3.15e-15

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 82.71 E-value: 3.15e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1417 KREMTKEERDMSEEVEEMATLEEKVVKQEGKLvmiERTPSWQdwkkawdewKQVHGETRKSWKAWKEEWEKRLLQEEEKL 1496
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQ---EEQLKKQ---------QLLKQLRARIEELRAQEAVLEETQERINR 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1497 HQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWAR 1576
Cdd:TIGR00618  289 ARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIR 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1577 IHRKRARAEKKRAqeeRKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF--AQKEETLAQRGEKLSQE 1654
Cdd:TIGR00618  369 EISCQQHTLTQHI---HTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLahAKKQQELQQRYAELCAA 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1655 AeklAQKRKKLAKKWEKVARE-EEKLAKKGGKLAEVKNILAQ---------KVEELPQREQNLDWQEKELAQELEELEWD 1724
Cdd:TIGR00618  446 A---ITCTAQCEKLEKIHLQEsAQSLKEREQQLQTKEQIHLQetrkkavvlARLLELQEEPCPLCGSCIHPNPARQDIDN 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1725 MEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRK-RE 1803
Cdd:TIGR00618  523 PGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLtEK 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1804 QLIEKKMKLAQKRERWINSMEELTKNKMILYQKknlaQEKKNLAQEKEKLAQRKENLLYNKERltHSKKQLVQVKNKLGM 1883
Cdd:TIGR00618  603 LSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQ----QCSQELALKLTALHALQLTLTQERVR--EHALSIRVLPKELLA 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1884 FNKILaqvEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLaKKQEKLAQEkmklaLEKAMVQGKKRLRGELDIAKEekaL 1963
Cdd:TIGR00618  677 SRQLA---LQKMQSEKEQLTYWKEMLAQCQTLLRELETHI-EEYDREFNE-----IENASSSLGSDLAAREDALNQ---S 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1964 NLEMKRLAEEKMR-LVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLhedriLAMEESEIakgkleftrGQ 2042
Cdd:TIGR00618  745 LKELMHQARTVLKaRTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHL-----LKTLEAEI---------GQ 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2043 RIFVQGQRKLAKaSRKLIKKRESLSKEPAKLNKILKAL-QKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIK 2121
Cdd:TIGR00618  811 EIPSDEDILNLQ-CETLVQEEEQFLSRLEEKSATLGEItHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFD 889

                          730       740
                   ....*....|....*....|..
gi 597709775  2122 EWDFSEKRSELTKDEKKLARKQ 2143
Cdd:TIGR00618  890 GDALIKFLHEITLYANVRLANQ 911

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1483-2171

9.41e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 81.27 E-value: 9.41e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1483 EEWEKRLLQEEEKLHQAGEKL----SPEEEMLQEDKKLKWEEWKQvwENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKE 1558
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIerldLIIDEKRQQLERLRREREKA--ERYQALLKEKREYEGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1559 QQVTEEQRHIQEEHKWARIHRKR-ARAEKKRAQEERKL-AQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRlEEIEQLLEELNKKIkDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1637 FAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQ 1716
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1717 ELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEK 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1797 RLGRKREQLI--EKKMKLAQKRERWINSMEELTK--NKMIL------------YQK----------KNLAQEKKNLAQE- 1849
Cdd:TIGR02169  484 ELSKLQRELAeaEAQARASEERVRGGRAVEEVLKasIQGVHgtvaqlgsvgerYATaievaagnrlNNVVVEDDAVAKEa 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1850 ----KEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGM----------FNKILAQV------EEKLTQEKETVIKKK--- 1906
Cdd:TIGR02169  564 iellKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFavdlvefdpkYEPAFKYVfgdtlvVEDIEAARRLMGKYRmvt 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1907 ------EKL------AETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKK-RLRGELDIAKEEKALNLEMKRLAEE 1973
Cdd:TIGR02169  644 legelfEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELrRIENRLDELSQELSDASRKIGEIEK 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1974 KMRLVEGKETLSKGETPETsrQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLA 2053
Cdd:TIGR02169  724 EIEQLEQEEEKLKERLEEL--EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2054 KASRKLIKKRESLSKEPAKLNKILKALQKLtRDERKLTQEEIKMTKMKRalfvKERRLSIEQSKLDIKEWDFSEKR---- 2129
Cdd:TIGR02169  802 KLEEEVSRIEARLREIEQKLNRLTLEKEYL-EKEIQELQEQRIDLKEQI----KSIEKEIENLNGKKEELEEELEEleaa 876

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 597709775  2130 -SELTKDEKKLARKQRKLANKMRRMINKEEKMtEEESKLARKH 2171
Cdd:TIGR02169  877 lRDLESRLGDLKKERDELEAQLRELERKIEEL-EAQIEKKRKR 918

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1583-2237

1.92e-14

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.10 E-value: 1.92e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1583 RAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFaqkeETLAQRGEKLSQEAEKLAQKR 1662
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL----YALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1663 KKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQeleelewDMEELSWKEEELNQEEGKL 1742
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA-------ELEELESRLEELEEQLETL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1743 VEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKE--KMPEEEERLGRKREQLIEKKMKLAQKRERWI 1820
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeaELKELQAELEELEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1821 NSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMfnkiLAQVEEKLTQEKE 1900
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSE----LISVDEGYEAAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1901 TVikkkekLAETEKKLVQVEDSLAKK-QEKLAQEKMKLA------------LEKAMVQGKKRLRGELDIAKE-------- 1959
Cdd:TIGR02168  541 AA------LGGRLQAVVVENLNAAKKaIAFLKQNELGRVtflpldsikgteIQGNDREILKNIEGFLGVAKDlvkfdpkl 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1960 EKALN---------------LEMKRLAEEKMRLVegkeTLsKGE--TPETSRQRKMTQVEQELFERKLSLEEkillHEDR 2022
Cdd:TIGR02168  615 RKALSyllggvlvvddldnaLELAKKLRPGYRIV----TL-DGDlvRPGGVITGGSAKTNSSILERRREIEE----LEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2023 ILAMEES------EIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIK 2096
Cdd:TIGR02168  686 IEELEEKiaelekALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2097 MTKMKRALF---------VKERRLSIEQSKLDIKEWD--FSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEES 2165
Cdd:TIGR02168  766 LEERLEEAEeelaeaeaeIEELEAQIEQLKEELKALReaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 597709775  2166 KLARKhsevilddeeeggieeeevipflkrrwrkrkeakrgdkpkekfssqvdeveseehfSEEMESLLDEL 2237
Cdd:TIGR02168  846 QIEEL--------------------------------------------------------SEDIESLAAEI 861

PRK03918

DNA double-strand break repair ATPase Rad50;

1761-2248

2.19e-14

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 79.72 E-value: 2.19e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMpeeEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLA 1840
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENI---EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELK 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1841 QEKKNLAQEKEKLAQRKENLlynKERLTHSKKQLVQVKNKLGMFNKILAQVEEkLTQEKETVIKKKEKLAETEKKLVQVE 1920
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKL---EEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYEEYLDELREIE 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1921 DSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPET-------- 1992
Cdd:PRK03918  314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTpeklekel 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1993 ----SRQRKMTQVEQELFERKLSLEEKIllhEDRILAMEESEIAKGKLEFTRgqrifvqgqRKLAKASRKLIKKR----- 2063
Cdd:PRK03918  394 eeleKAKEEIEEEISKITARIGELKKEI---KELKKAIEELKKAKGKCPVCG---------RELTEEHRKELLEEytael 461

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2064 ESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRAL----FVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKL 2139
Cdd:PRK03918  462 KRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqlkELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEI 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2140 ------ARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKR-------RWRKRKEAKRG 2206
Cdd:PRK03918  542 kslkkeLEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEylelkdaEKELEREEKEL 621

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|..
gi 597709775 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEE 2248
Cdd:PRK03918  622 KKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEE 663

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1576-2237

2.97e-14

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 79.34 E-value: 2.97e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1576 RIHRKRARAEKKRAQEERkLAQEEEKLaqEERQLAQEERKLAQAYVKITQ---DDREMAQAEGKFAQKEETLAQRGEKLS 1652
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLER-LRREREKA--ERYQALLKEKREYEGYELLKEkeaLERQKEAIERQLASLEEELEKLTEEIS 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1653 QEAEKLAQKRKKLAKKWEKVAR--EEEKLAKKGgKLAEVKNILAQ---KVEELPQREQNLDWQEKELAQELEELEWDMEE 1727
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDlgEEEQLRVKE-KIGELEAEIASlerSIAEKERELEDAEERLAKLEAEIDKLLAEIEE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1728 LSWKEEELNQEEGKLVEEKKKLAEEEEALawqREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEE-------ERLGR 1800
Cdd:TIGR02169  341 LEREIEEERKRRDKLTEEYAELKEELEDL---RAELEEVDKEFAETRDELKDYREKLEKLKREINELKreldrlqEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1801 KREQLIEKKMKLAQKRERwINSMEE--LTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVK 1878
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAK-INELEEekEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1879 NKLG--------------MFNK----ILAQVEEkLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ--EKLAQEKMK-- 1936
Cdd:TIGR02169  497 AQARaseervrggraveeVLKAsiqgVHGTVAQ-LGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEaiELLKRRKAGra 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1937 --LALEKAmvqgkKRLRGELDIAKEEK----ALNL-EMKRLAEEKMRLVEGKETLSkgETPETSR----QRKMTQVEQEL 2005
Cdd:TIGR02169  576 tfLPLNKM-----RDERRDLSILSEDGvigfAVDLvEFDPKYEPAFKYVFGDTLVV--EDIEAARrlmgKYRMVTLEGEL 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2006 FER-----------------KLSLEEKILLHEDRILAMEEsEIAKGKLEFTRGQRIFVQGQRKLAKASRKLI---KKRES 2065
Cdd:TIGR02169  649 FEKsgamtggsraprggilfSRSEPAELQRLRERLEGLKR-ELSSLQSELRRIENRLDELSQELSDASRKIGeieKEIEQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2066 LSKEPAKLNKILKALQ-KLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQR 2144
Cdd:TIGR02169  728 LEQEEEKLKERLEELEeDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEV 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2145 KLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIeeeevipflkRRWRKRKEAKRGDKPKEKFSSQVDEVESEE 2224
Cdd:TIGR02169  808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE----------QIKSIEKEIENLNGKKEELEEELEELEAAL 877

                          730
                   ....*....|...
gi 597709775  2225 hfsEEMESLLDEL 2237
Cdd:TIGR02169  878 ---RDLESRLGDL 887

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1479-2178

5.16e-14

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 78.22 E-value: 5.16e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1479 KAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDK------KLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSR 1552
Cdd:pfam05483   91 KKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQfenekvSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEK 170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1553 EGEEKEQQvtEEQRHI------QEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQE----ERKLAQAYVK 1622
Cdd:pfam05483  171 TKKYEYER--EETRQVymdlnnNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEindkEKQVSLLLIQ 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1623 ITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQ---KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEE 1699
Cdd:pfam05483  249 ITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKElieKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQ 328

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1700 LPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQ 1779
Cdd:pfam05483  329 LTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1780 EKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLA---QKRERWINSME-ELTKNKMilyQKKNLAQEKKNLAQEKEKLAQ 1855
Cdd:pfam05483  409 ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIfllQAREKEIHDLEiQLTAIKT---SEEHYLKEVEDLKTELEKEKL 485

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1856 RKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEkklVQVEDSLAKKQEKLAQ--E 1933
Cdd:pfam05483  486 KNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE---MNLRDELESVREEFIQkgD 562

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1934 KMKLALEKAmvqgkkrlrgeldiakEEKALNLEMKRLAEEK-MRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSL 2012
Cdd:pfam05483  563 EVKCKLDKS----------------EENARSIEYEVLKKEKqMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSA 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2013 EEKIL-LHEDRILAME-ESEIAKGKL-EFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKalqklTRDERK 2089
Cdd:pfam05483  627 ENKQLnAYEIKVNKLElELASAKQKFeEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID-----KRCQHK 701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2090 LTQEEIKMTKMKRAL--FVKERRLSI--------EQSKLDIK-EWDFSEKRSELTKDEKKLArkqrklankmrrmINKEE 2158
Cdd:pfam05483  702 IAEMVALMEKHKHQYdkIIEERDSELglyknkeqEQSSAKAAlEIELSNIKAELLSLKKQLE-------------IEKEE 768

                          730       740
                   ....*....|....*....|
gi 597709775  2159 KmteEESKLARKHSEVILDD 2178
Cdd:pfam05483  769 K---EKLKMEAKENTAILKD 785

PTZ00121

MAEBL; Provisional

1585-2287

3.32e-13

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 76.33 E-value: 3.32e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1585 EKKRAQEERKLAQ---EEEKLAQEERQLAQEERKLAQayVKITQDDREMAQAEGKFAQKEETLAQRGEklsqEAEKLAQK 1661
Cdd:PTZ00121 1096 AFGKAEEAKKTETgkaEEARKAEEAKKKAEDARKAEE--ARKAEDARKAEEARKAEDAKRVEIARKAE----DARKAEEA 1169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1662 RK-KLAKKWEKVAREEE-KLAKKGGKLAEVKNILAQKVEELPQReqnldwqekelaqeleelewdMEELSWKEEELNQEE 1739
Cdd:PTZ00121 1170 RKaEDAKKAEAARKAEEvRKAEELRKAEDARKAEAARKAEEERK---------------------AEEARKAEDAKKAEA 1228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1740 GKLVeekkklaeeeealawQREKLSEEETKLAQE----EELLIQEKEKLAQHKEKMPEEEERLGRKREQLiekkmklaqK 1815
Cdd:PTZ00121 1229 VKKA---------------EEAKKDAEEAKKAEEernnEEIRKFEEARMAHFARRQAAIKAEEARKADEL---------K 1284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1816 RERWINSMEELTKNkmilyQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKlgmfnkilAQVEEKL 1895
Cdd:PTZ00121 1285 KAEEKKKADEAKKA-----EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKA--------AEAAKAE 1351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1896 TQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKM 1975
Cdd:PTZ00121 1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKK 1431

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1976 RLVEGKEtlskgetpETSRQRKMTQVEQELFERKLSLEEKILLHEDRilameESEIAKGKLEftrgqrifvqgqrkLAKA 2055
Cdd:PTZ00121 1432 KADEAKK--------KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK-----KADEAKKKAE--------------EAKK 1484

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2056 SRKLIKKRESLSKEPAKLNKilKALQKLTRDERKLTQEEIKMTKMKRAlfvKERRLSIEQSKLD-IKEWDFSEKRSELTK 2134
Cdd:PTZ00121 1485 ADEAKKKAEEAKKKADEAKK--AAEAKKKADEAKKAEEAKKADEAKKA---EEAKKADEAKKAEeKKKADELKKAEELKK 1559

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2135 DEKKLARKQRKLANKMRRMINKEekmTEEESKLARKHSEVILDdeeeggieeeeviPFLKRRWRKRKEAKRGDKPKEKfS 2214
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRK---AEEAKKAEEARIEEVMK-------------LYEEEKKMKAEEAKKAEEAKIK-A 1622

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 597709775 2215 SQVDEVESEEHFSEEMESLLDElekqeslsseeeeereeeeerEEEEEREEEEERKEEEEGEEKQVEKEEEEK 2287
Cdd:PTZ00121 1623 EELKKAEEEKKKVEQLKKKEAE---------------------EKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1563-1873

4.72e-13

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.49 E-value: 4.72e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1563 EEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEklAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEE 1642
Cdd:TIGR02169  695 SELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE--EKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEE 772

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1643 TLAQRGEKLS-----------QEAEKLAQKRKKLAKKWEKVAREEEKlakKGGKLAEVKNILAQKVEELPQREQNLDWQE 1711
Cdd:TIGR02169  773 DLHKLEEALNdlearlshsriPEIQAELSKLEEEVSRIEARLREIEQ---KLNRLTLEKEYLEKEIQELQEQRIDLKEQI 849

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1712 KELAQELEELEWDMEELSWKEEE----LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQH 1787
Cdd:TIGR02169  850 KSIEKEIENLNGKKEELEEELEEleaaLRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEAL 929

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1788 KEKMPEEEERLGRKREQ-----LIEKKMKLAQKRERWINSMEELtkNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLY 1862
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIpeeelSLEDVQAELQRVEEEIRALEPV--NMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007

                          330
                   ....*....|.
gi 597709775  1863 NKERLTHSKKQ 1873
Cdd:TIGR02169 1008 RIEEYEKKKRE 1018

sbcc

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1628-2147

5.23e-13

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 75.39 E-value: 5.23e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1628 REMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707
Cdd:TIGR00618  145 RVVLLPQGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVL 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1708 DWQEKELAQELEELEWDMEELSWKEEELNQEEGKlveekkklaeeEEALAWQREKLSEEETKLAQEEELliQEKEKLAQH 1787
Cdd:TIGR00618  225 EKELKHLREALQQTQQSHAYLTQKREAQEEQLKK-----------QQLLKQLRARIEELRAQEAVLEET--QERINRARK 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1788 KEKMPEEEERLGRKREQ-------LIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENL 1860
Cdd:TIGR00618  292 AAPLAAHIKAVTQIEQQaqrihteLQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREIS 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1861 LYNKErLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQvedslAKKQEKLAQEkmKLALE 1940
Cdd:TIGR00618  372 CQQHT-LTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH-----AKKQQELQQR--YAELC 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1941 KAMVQgkkrlrGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETpETSRQRKmtQVEQELFERKLSLEEKIL-LH 2019
Cdd:TIGR00618  444 AAAIT------CTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQET-RKKAVVL--ARLLELQEEPCPLCGSCIhPN 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2020 EDRILAME-----------ESEIAKGK--LEFTRGQRIFVQGQRKLAKASRKLIKKRES-LSKEPAKLNKILKALQKLTR 2085
Cdd:TIGR00618  515 PARQDIDNpgpltrrmqrgEQTYAQLEtsEEDVYHQLTSERKQRASLKEQMQEIQQSFSiLTQCDNRSKEDIPNLQNITV 594

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 597709775  2086 DERKLTQEEIKMTKMKR-ALFVKERRLSIEQSKLDIKEWDfSEKRSELTKDEKKLARKQRKLA 2147
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLAcEQHALLRKLQPEQDLQDVRLHL-QQCSQELALKLTALHALQLTLT 656

sbcc

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1558-2161

3.13e-12

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 72.69 E-value: 3.13e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1558 EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQeerklaqayvkitqddremaqaegkf 1637
Cdd:TIGR00618  228 LKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEE-------------------------- 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKkggKLAEVKNILAQKVEELPQREQNLDWQekelAQE 1717
Cdd:TIGR00618  282 TQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAK---LLMKRAAHVKQQSSIEEQRRLLQTLH----SQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1718 LEELEWDMEELSWKEE-----ELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAqHKEKMP 1792
Cdd:TIGR00618  355 IHIRDAHEVATSIREIscqqhTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLA-HAKKQQ 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1793 EEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKM-ILYQKKNLAQEKKNLAQEKEKLAQR-KENLLYNKERLTHS 1870
Cdd:TIGR00618  434 ELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREqQLQTKEQIHLQETRKKAVVLARLLElQEEPCPLCGSCIHP 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1871 KKQLVQV-------------KNKLGMFNKILAQVEEKLTQEKETVIKKKEK-----------------LAETEKKLVQVE 1920
Cdd:TIGR00618  514 NPARQDIdnpgpltrrmqrgEQTYAQLETSEEDVYHQLTSERKQRASLKEQmqeiqqsfsiltqcdnrSKEDIPNLQNIT 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1921 DSLAKKQEKLAQEKMKLALEkamvQGKKRLRGELDIAKEEKALNLEM--KRLAEEKMRLVEGKETLSKGETPETSrqRKM 1998
Cdd:TIGR00618  594 VRLQDLTEKLSEAEDMLACE----QHALLRKLQPEQDLQDVRLHLQQcsQELALKLTALHALQLTLTQERVREHA--LSI 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1999 TQVEQELFERKLSLEEKI-------------LLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLA---KASRKLIKK 2062
Cdd:TIGR00618  668 RVLPKELLASRQLALQKMqsekeqltywkemLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAareDALNQSLKE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2063 RESLSKEP--AKLNKILKALQKLTRDERKLTQEEikmtKMKRALFVKERRLSIEQSKLDIKEwdfSEKRSELTKDEKKLA 2140
Cdd:TIGR00618  748 LMHQARTVlkARTEAHFNNNEEVTAALQTGAELS----HLAAEIQFFNRLREEDTHLLKTLE---AEIGQEIPSDEDILN 820

                          650       660
                   ....*....|....*....|.
gi 597709775  2141 RKQRKLANKMRRMINKEEKMT 2161
Cdd:TIGR00618  821 LQCETLVQEEEQFLSRLEEKS 841

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

213-492

1.15e-11

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 68.13 E-value: 1.15e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  213 DQGFLYAGNQAGEIQVWSLQQGHPLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWNLTSGSLLRRLElG--EELYR 290
Cdd:cd00200    20 DGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLT-GhtSYVSS 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  291 LQFIDSITFFC-----QTAHSFSLHRLPCFYSLfnvcgsaPQQLRRVCC----GNNWFrILCTTEDGLLRFVSPVTGdLL 361
Cdd:cd00200    99 VAFSPDGRILSsssrdKTIKVWDVETGKCLTTL-------RGHTDWVNSvafsPDGTF-VASSSQDGTIKLWDLRTG-KC 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  362 VITwpFSILDQAVDW-AYDPGKEELFVATGSSEVLVFDTTrcpcpAKYLLGTSPNSQDFVQCLAYGHFNLgrglegLIFS 440
Cdd:cd00200   170 VAT--LTGHTGEVNSvAFSPDGEKLLSSSSDGTIKLWDLS-----TGKCLGTLRGHENGVNSVAFSPDGY------LLAS 236

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 597709775  441 GHQSGVIRVLSQHSCARLEKF-MHFGAVLALSTLSGGIFggqgnslLCSYGMD 492
Cdd:cd00200   237 GSEDGTIRVWDLRTGECVQTLsGHTNSVTSLAWSPDGKR-------LASGSAD 282

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1557-1861

1.51e-11

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 1.51e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1557 KEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1637 FAQKEETLAQRGEKLSQEAEKLAQKRKK---LAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKE 1713
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRledLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1714 LAQeleelewDMEELSWKEEELNQEEGKLVEEKKKlaeeeealawQREKLSEEETKLAQEEELLIQEKEKLAQ------- 1786
Cdd:TIGR02168  892 LRS-------ELEELSEELRELESKRSELRRELEE----------LREKLAQLELRLEGLEVRIDNLQERLSEeysltle 954

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775  1787 -HKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELtknkmilyqkKNLAQEKKNLAQEKEKLAQRKENLL 1861
Cdd:TIGR02168  955 eAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEY----------EELKERYDFLTAQKEDLTEAKETLE 1020

WD40

COG2319

WD40 repeat [General function prediction only];

213-598

2.13e-11

WD40 repeat [General function prediction only];

Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 68.78 E-value: 2.13e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  213 DQGFLYAGNQAGEIQVWSLQQGHPLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWNLTSGSLLRRLELGEElyrlq 292
Cdd:COG2319    89 DGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSG----- 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  293 FIDSITFfcqtahsfslhrlpcfyslfnvcgSAPQQlrrvccgnnwfRILCTTEDGLLRFVSPVTGDLLvitWPFSILDQ 372
Cdd:COG2319   164 AVTSVAF------------------------SPDGK-----------LLASGSDDGTVRLWDLATGKLL---RTLTGHTG 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  373 AV-DWAYDP-GKeelFVATGSS--EVLVFDTTRCPCpakylLGTSPNSQDFVQCLAY---GHfnlgrglegLIFSGHQSG 445
Cdd:COG2319   206 AVrSVAFSPdGK---LLASGSAdgTVRLWDLATGKL-----LRTLTGHSGSVRSVAFspdGR---------LLASGSADG 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  446 VIRV--LSQHSCARLEKfMHFGAVLALStlsggiFGGQGNSLLcSYGMDDYVHL----SEAVLDGVKVQLRPLASILSSc 519
Cdd:COG2319   269 TVRLwdLATGELLRTLT-GHSGGVNSVA------FSPDGKLLA-SGSDDGTVRLwdlaTGKLLRTLTGHTGAVRSVAFS- 339

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  520 hlthlillP--KSVGAITETNCLRLWkfhdflssgSQNGLKFIETLPLHLCAITSfdVCLSL--SLFVTGSADGSVRIWD 595
Cdd:COG2319   340 --------PdgKTLASGSDDGTVRLW---------DLATGELLRTLTGHTGAVTS--VAFSPdgRTLASGSADGTVRLWD 400


                  ...
gi 597709775  596 FHG 598
Cdd:COG2319   401 LAT 403

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1610-1961

3.99e-11

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.33 E-value: 3.99e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1610 AQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLA----------QRGEKLSQEAEKlAQKRKKLAKKWEKVaREEEKL 1679
Cdd:TIGR02169  152 PVERRKIIDEIAGVAEFDRKKEKALEELEEVEENIErldliidekrQQLERLRREREK-AERYQALLKEKREY-EGYELL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1680 AKKGGKLAEVKNILAQ---KVEELPQREQNLDwqekelaqeleELEWDMEELSWKEEELN-------QEEGKLVEEKKKL 1749
Cdd:TIGR02169  230 KEKEALERQKEAIERQlasLEEELEKLTEEIS-----------ELEKRLEEIEQLLEELNkkikdlgEEEQLRVKEKIGE 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1750 AEEEEALAWQREKLSEEETKLAQEEEL-LIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTK 1828
Cdd:TIGR02169  299 LEAEIASLERSIAEKERELEDAEERLAkLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1829 nkmilyQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQvknKLGMFNKILAQVEEKLTQEKETVIKKKEK 1908
Cdd:TIGR02169  379 ------EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE---ELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 597709775  1909 LAETEKKLVQVEDSLAKKQEKLAQEKMKLA-LEKAMvqgkKRLRGELDIAKEEK 1961
Cdd:TIGR02169  450 IKKQEWKLEQLAADLSKYEQELYDLKEEYDrVEKEL----SKLQRELAEAEAQA 499

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

236-625

5.34e-11

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 66.20 E-value: 5.34e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  236 PLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWNLTSGSLLRRLelgeelyrlqfidsitffcqTAHSFSLHRLpcf 315
Cdd:cd00200     1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTL--------------------KGHTGPVRDV--- 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  316 yslfnvcgsapqqlrRVCCGNNWfrILCTTEDGLLRFVSPVTGDLLvitwpfSIL---DQAV-DWAYDPGKEelFVATGS 391
Cdd:cd00200    58 ---------------AASADGTY--LASGSSDKTIRLWDLETGECV------RTLtghTSYVsSVAFSPDGR--ILSSSS 112

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  392 S--EVLVFDTTRCPCpakylLGTSPNSQDFVQCLAYGHFNlgrgleGLIFSGHQSGVIRV--LSQHSC-ARLEkfMHFGA 466
Cdd:cd00200   113 RdkTIKVWDVETGKC-----LTTLRGHTDWVNSVAFSPDG------TFVASSSQDGTIKLwdLRTGKCvATLT--GHTGE 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  467 VLALStlsggiFGGQGNSLLCSyGMDdyvhlseavldgvkvqlrplasilsschlthlillpksvgaitetNCLRLWKFH 546
Cdd:cd00200   180 VNSVA------FSPDGEKLLSS-SSD---------------------------------------------GTIKLWDLS 207

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  547 DFlssgsqnglKFIETLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWDFH-GRLIGILdsSLHFGPV---CFANDRGDL 622
Cdd:cd00200   208 TG---------KCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRtGECVQTL--SGHTNSVtslAWSPDGKRL 276


                  ...
gi 597709775  623 LVT 625
Cdd:cd00200   277 ASG 279

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1405-2043

9.31e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.04 E-value: 9.31e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1405 KAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIErtpswqdwkKAWDEWKQVHGETRKSwkawKEE 1484
Cdd:COG1196   219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE---------AELEELRLELEELELE----LEE 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1485 WEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKwEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEE 1564
Cdd:COG1196   286 AQAEEYELLAELARLEQDIARLEERRRELEERL-EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1565 QRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQL-AQEERkLAQAYVKITQDDREMAQAEGKFAQKEET 1643
Cdd:COG1196   365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEeALLER-LERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1644 LAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL-DWQEKELAQELEELE 1722
Cdd:COG1196   444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLeGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1723 WDMEELSWKEEELNQEEGklveekkklaeeEEALAWQREKLSEEETKLAQEEELLiqekeklaqhkekmpeEEERLGRKR 1802
Cdd:COG1196   524 GAVAVLIGVEAAYEAALE------------AALAAALQNIVVEDDEVAAAAIEYL----------------KAAKAGRAT 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1803 EQLIEkKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLG 1882
Cdd:COG1196   576 FLPLD-KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1883 MFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKA 1962
Cdd:COG1196   655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1963 LNLEMKRLAEEKMRLVEGKETLSKGETPEtsrqrkmtQVEQELFErklsLEEKIllheDRI-----LAMEESEIAKGKLE 2037
Cdd:COG1196   735 EELLEELLEEEELLEEEALEELPEPPDLE--------ELERELER----LEREI----EALgpvnlLAIEEYEELEERYD 798


                  ....*.
gi 597709775 2038 FTRGQR 2043
Cdd:COG1196   799 FLSEQR 804

PRK12704

phosphodiesterase; Provisional

1577-1700

4.26e-10

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 65.18 E-value: 4.26e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1577 IHRKRARAEKKRAQEE-RKLAQEEEKLAQEERQLAQEERKlaQAYVKITQD-DREMAQAEGKFAQKEETLAQRGEKLSQE 1654
Cdd:PRK12704   24 VRKKIAEAKIKEAEEEaKRILEEAKKEAEAIKKEALLEAK--EEIHKLRNEfEKELRERRNELQKLEKRLLQKEENLDRK 101

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 597709775 1655 AEKLAQKRKKLAKKWEKVAREEEKLAKkggKLAEVKNILAQKVEEL 1700
Cdd:PRK12704  102 LELLEKREEELEKKEKELEQKQQELEK---KEEELEELIEEQLQEL 144

tolA

cell envelope integrity inner membrane protein TolA; Provisional

1519-1696

6.61e-10

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 64.06 E-value: 6.61e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1519 EEWKQVWENMLSSKSKEQQYKdeeevtlEEEVSREGEEKEQQVTEEQRHIQEEHKwarihRKRARAEKKRAQEERKLAQE 1598
Cdd:PRK09510   62 EQYNRQQQQQKSAKRAEEQRK-------KKEQQQAEELQQKQAAEQERLKQLEKE-----RLAAQEQKKQAEEAAKQAAL 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1599 EEKLAQEERQLA---------QEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGE----KLSQEAEKLAQKRKKL 1665
Cdd:PRK09510  130 KQKQAEEAAAKAaaaakakaeAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAeaaaKAAAEAKKKAEAEAKK 209

                         170       180       190
                  ....*....|....*....|....*....|.
gi 597709775 1666 AKKWEKVAREEEKLAKKGGKLAEVKNILAQK 1696
Cdd:PRK09510  210 KAAAEAKKKAAAEAKAAAAKAAAEAKAAAEK 240

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1771-2122

1.16e-09

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.32 E-value: 1.16e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1771 AQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERwinsMEELT--KNKMILYQ---KKNLAQEKKN 1845
Cdd:TIGR02169  152 PVERRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQ----LERLRreREKAERYQallKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1846 LAQEKEKLAQRKENLLYNKERLThskKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKK--------KEKLAETEKKLV 1917
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLE---EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvKEKIGELEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1918 QVEDSLAKKQEKLAQekmklaLEKAMVQGKKRLRgeldiAKEEKALNLEmKRLAEEKMRLVEGKETLSKGETPETSRQRK 1997
Cdd:TIGR02169  305 SLERSIAEKERELED------AEERLAKLEAEID-----KLLAEIEELE-REIEEERKRRDKLTEEYAELKEELEDLRAE 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1998 MTQVE---QELFERKLSLEEKIllhEDRILAMEESEIAKGKLEfTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLN 2074
Cdd:TIGR02169  373 LEEVDkefAETRDELKDYREKL---EKLKREINELKRELDRLQ-EELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL 448

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 597709775  2075 KILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKE 2122
Cdd:TIGR02169  449 EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAE 496

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1818-2170

1.41e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 64.30 E-value: 1.41e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1818 RWINSMEELTKNKMILYQK-KNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLT 1896
Cdd:TIGR00606  183 RYIKALETLRQVRQTQGQKvQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLS 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1897 Q--EKETVIKKKEKlaeTEKKLVQVEDSLAKKQEKLAQ---EKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLA 1971
Cdd:TIGR00606  263 KimKLDNEIKALKS---RKKQMEKDNSELELKMEKVFQgtdEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLN 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1972 EEKMRLV--EGKETLSKGETPETSRQRKM------TQVEQELFERKLSLEEKIL-LHEDRILAMEESE--IAKGKLEFTR 2040
Cdd:TIGR00606  340 QEKTELLveQGRLQLQADRHQEHIRARDSliqslaTRLELDGFERGPFSERQIKnFHTLVIERQEDEAktAAQLCADLQS 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2041 ----GQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQS 2116
Cdd:TIGR00606  420 kerlKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETL 499

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 597709775  2117 KLDIKewdfsekrsELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESkLARK 2170
Cdd:TIGR00606  500 KKEVK---------SLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEM-LTKD 543

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1761-2243

1.42e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 63.89 E-value: 1.42e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL------IEKKMKLAQKRERWINSMEE----LTKNK 1830
Cdd:TIGR04523  155 EKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLelllsnLKKKIQKNKSLESQISELKKqnnqLKDNI 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1831 MILYQKKNlaQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVE---EKLTQEKETVIKK-- 1905
Cdd:TIGR04523  235 EKKQQEIN--EKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKseiSDLNNQKEQDWNKel 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKalNLEMKRLAEEKMRLVEGKETLS 1985
Cdd:TIGR04523  313 KSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEK--QNEIEKLKKENQSYKQEIKNLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1986 KGETPETSRQRKMTQVEQELFER-------KLSLEEKI-LLHEDRILAMEE-----SEIAKGKLEFTRGQRIFVQGQRKL 2052
Cdd:TIGR04523  391 SQINDLESKIQNQEKLNQQKDEQikklqqeKELLEKEIeRLKETIIKNNSEikdltNQDSVKELIIKNLDNTRESLETQL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2053 AKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKewdFSEKRSEL 2132
Cdd:TIGR04523  471 KVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK---ISDLEDEL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2133 TKDEKKLARKQRKlanKMRRMINKE-EKMTEEESKLARKHSEvilddeeeggieeeevipflKRRWRKRKEAKRGDKPKE 2211
Cdd:TIGR04523  548 NKDDFELKKENLE---KEIDEKNKEiEELKQTQKSLKKKQEE--------------------KQELIDQKEKEKKDLIKE 604

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 597709775  2212 ------KFSSQVDEVESEEHFSEEMESLLDELEKQESL 2243
Cdd:TIGR04523  605 ieekekKISSLEKELEKAKKENEKLSSIIKNIKSKKNK 642

mukB

PRK04863

chromosome partition protein MukB;

1760-2159

1.91e-09

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 63.82 E-value: 1.91e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1760 REKLSEEETKLAQEEELLIQEKEKLAQHKEKM-------PE----EEERLGrKREQLIEKKMKLAQKRERWINSmeeltk 1828
Cdd:PRK04863  843 NRRRVELERALADHESQEQQQRSQLEQAKEGLsalnrllPRlnllADETLA-DRVEEIREQLDEAEEAKRFVQQ------ 915

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1829 nkmilyQKKNLAQEKKNLA---QEKEKLAQRKENLLYNKERLTHSKKQ------LVQVKNKLGMfnkilAQVEEKLTQEK 1899
Cdd:PRK04863  916 ------HGNALAQLEPIVSvlqSDPEQFEQLKQDYQQAQQTQRDAKQQafalteVVQRRAHFSY-----EDAAEMLAKNS 984

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1900 ETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELdiAKEEKALNLEMKRLAEEKMRLve 1979
Cdd:PRK04863  985 DLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQEL--KQELQDLGVPADSGAEERARA-- 1060

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1980 GKETLSkgETPETSRQRKmTQVEQEL--FERKL-SLEEKI-LLHEDRILAMEESEIAKGkleftRGQRIfvqgqRKLAKA 2055
Cdd:PRK04863 1061 RRDELH--ARLSANRSRR-NQLEKQLtfCEAEMdNLTKKLrKLERDYHEMREQVVNAKA-----GWCAV-----LRLVKD 1127

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2056 S---RKLiKKRE----SLSKEPAKLNKILKALQKLTRDERKLTQ-----EEIKMTKMKRALFVKERRLSIEQSKLDIKEW 2123
Cdd:PRK04863 1128 NgveRRL-HRRElaylSADELRSMSDKALGALRLAVADNEHLRDvlrlsEDPKRPERKVQFYIAVYQHLRERIRQDIIRT 1206

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 597709775 2124 D------------FSEKRSELTKDEKKLARKQRKLANKMRRMINKEEK 2159
Cdd:PRK04863 1207 DdpveaieqmeieLSRLTEELTSREQKLAISSESVANIIRKTIQREQN 1254

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1401-2015

5.68e-09

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 62.05 E-value: 5.68e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1401 KQGRKAVQKERKVGKIKREMTKEERDMSEEVEemATLEEKVvkQEGKLVMIER--TPSWQDWKK--------AWDEWKQV 1470
Cdd:pfam05483  102 KQKENKLQENRKIIEAQRKAIQELQFENEKVS--LKLEEEI--QENKDLIKENnaTRHLCNLLKetcarsaeKTKKYEYE 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1471 HGETRKSWKAWKEEWEKRLLQEEEKLHQAGE-------KLSPEEEMLQ----EDKKLKWEEWKQVWENMLSSKSKEQQYK 1539
Cdd:pfam05483  178 REETRQVYMDLNNNIEKMILAFEELRVQAENarlemhfKLKEDHEKIQhleeEYKKEINDKEKQVSLLLIQITEKENKMK 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1540 DEEEVTLEEEVSREGEEKE--------QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQ 1611
Cdd:pfam05483  258 DLTFLLEESRDKANQLEEKtklqdenlKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQM 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1612 EERKLAQAYVKITqddreMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKN 1691
Cdd:pfam05483  338 EELNKAKAAHSFV-----VTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKK 412

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1692 ILAQK-------------VEELPQREQ--------------NLDWQEKELAQELEELEWDMEELS-------WKEEELNQ 1737
Cdd:pfam05483  413 ILAEDeklldekkqfekiAEELKGKEQelifllqarekeihDLEIQLTAIKTSEEHYLKEVEDLKtelekekLKNIELTA 492

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1738 EEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLgrkREQLIEK----KMKLA 1813
Cdd:pfam05483  493 HCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESV---REEFIQKgdevKCKLD 569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1814 QKRERWINSMEELTKN----KMILYQKKNLAQEKKNLAQEKEKLAQRKENLlynKERLTHSKKQLVQVKNKLGMFNKILA 1889
Cdd:pfam05483  570 KSEENARSIEYEVLKKekqmKILENKCNNLKKQIENKNKNIEELHQENKAL---KKKGSAENKQLNAYEIKVNKLELELA 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1890 QVEEKL-----TQEKETVIKK--KEK-LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRlrgELDIAKEEK 1961
Cdd:pfam05483  647 SAKQKFeeiidNYQKEIEDKKisEEKlLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKH---QYDKIIEER 723

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 597709775  1962 ALNLEM-KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFErKLSLEEK 2015
Cdd:pfam05483  724 DSELGLyKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKE-KLKMEAK 777

PRK03918

DNA double-strand break repair ATPase Rad50;

1404-1988

6.78e-09

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 61.62 E-value: 6.78e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1404 RKAVQKERKVGKIKREMTKEERDMSEEVEEmatLEEKVVKQEGKLVMIERtpSWQDWKKAWDEWKQVHGETRKSWKAwKE 1483
Cdd:PRK03918  182 EKFIKRTENIEELIKEKEKELEEVLREINE---ISSELPELREELEKLEK--EVKELEELKEEIEELEKELESLEGS-KR 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKdeeevtleeeVSREGEEKEQQVTE 1563
Cdd:PRK03918  256 KLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE----------IEKRLSRLEEEING 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1564 EQRHIQE-EHKWARIhrKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQayvkitqddREMAQAEGKFAQKEE 1642
Cdd:PRK03918  326 IEERIKElEEKEERL--EELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKK---------RLTGLTPEKLEKELE 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1643 TLAQRGEKLSQEAEKLAQKRKKLAKKWE--KVAREEEKLAKK-----GGKLAE--VKNILAQKVEELPQREQnldwqeke 1713
Cdd:PRK03918  395 ELEKAKEEIEEEISKITARIGELKKEIKelKKAIEELKKAKGkcpvcGRELTEehRKELLEEYTAELKRIEK-------- 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1714 laqeleelewDMEELSWKEEELNQEEGKLveekkklaeeeealawqrEKLSEEETKLAQEEELLIQEKEKLAQHKEKMPE 1793
Cdd:PRK03918  467 ----------ELKEIEEKERKLRKELREL------------------EKVLKKESELIKLKELAEQLKELEEKLKKYNLE 518

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1794 EEERLGRKREQLIEKKMKLAQKR---ERWINSMEELTKNKMILYQK-KNLAQEKKNLAQEKEKLAQRKENLLYNK-ERLT 1868
Cdd:PRK03918  519 ELEKKAEEYEKLKEKLIKLKGEIkslKKELEKLEELKKKLAELEKKlDELEEELAELLKELEELGFESVEELEERlKELE 598

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1869 HSKKQLVQVKNKlgmfNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMK------LALEKA 1942
Cdd:PRK03918  599 PFYNEYLELKDA----EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEelreeyLELSRE 674

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 597709775 1943 MVQGKKRLRgELDIAKEEKALNLEmkRLAEEKMRLVEGKETLSKGE 1988
Cdd:PRK03918  675 LAGLRAELE-ELEKRREEIKKTLE--KLKEELEEREKAKKELEKLE 717

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1584-1815

1.31e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.78 E-value: 1.31e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1584 AEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRK 1663
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1664 KLAKKWEKVAREEEKLAKKgGKLAEVKNILAQK-VEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKL 1742
Cdd:COG4942    98 ELEAQKEELAELLRALYRL-GRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 597709775 1743 VEEKKKLAEeeealawQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQK 1815
Cdd:COG4942   177 EALLAELEE-------ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242

tolA_full

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

1513-1690

2.53e-08

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 58.70 E-value: 2.53e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1513 DKKLKWEEWKQVWENMLSSKSKEQQykdeeevTLEEEVSREGEEKEQQVTEEQRHIQEEHkwarihRKRARAEKKRAQEE 1592
Cdd:TIGR02794   44 DPGAVAQQANRIQQQKKPAAKKEQE-------RQKKLEQQAEEAEKQRAAEQARQKELEQ------RAAAEKAAKQAEQA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1593 RKLAQEEEKLAQEERQLAQEERKLAqayvkitqddremAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKV 1672
Cdd:TIGR02794  111 AKQAEEKQKQAEEAKAKQAAEAKAK-------------AEAEAERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEA 177

                          170
                   ....*....|....*...
gi 597709775  1673 AREEEKLAKKGGKLAEVK 1690
Cdd:TIGR02794  178 EAKAKAEAEAKAKAEEAK 195

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1408-2043

2.58e-08

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.07 E-value: 2.58e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1408 QKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKL-----------VMIERTpswQDWKKAWDEWKQVHGETRK 1476
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyalaneisrleQQKQIL---RERLANLERQLEELEAQLE 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1477 SWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKL------KWEEWKQVWENM----------LSSKSKEQQYKD 1540
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEleelesRLEELEEQLETLrskvaqlelqIASLNNEIERLE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1541 EEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKwARIHRKRARAEKKRAQEERKLAQEE---EKLAQEERQLAQEERKLA 1617
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKELQ-AELEELEEELEELQEELERLEEALEelrEELEEAEQALDAAERELA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1618 QAYVKITQDDREMAQAEGKF-AQKEETLAQRG---------------EKLSQEAEK-----------------------L 1658
Cdd:TIGR02168  486 QLQARLDSLERLQENLEGFSeGVKALLKNQSGlsgilgvlselisvdEGYEAAIEAalggrlqavvvenlnaakkaiafL 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1659 AQKRK--------------------------------------KLAKKWEKV---------------------------- 1672
Cdd:TIGR02168  566 KQNELgrvtflpldsikgteiqgndreilkniegflgvakdlvKFDPKLRKAlsyllggvlvvddldnalelakklrpgy 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1673 ----------------------------------AREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL 1718
Cdd:TIGR02168  646 rivtldgdlvrpggvitggsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1719 EELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERL 1798
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1799 GRKREQLIEKKMKLAQKRERwinsMEELTKNK-MILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLThskKQLVQV 1877
Cdd:TIGR02168  806 DELRAELTLLNEEAANLRER----LESLERRIaATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE---SELEAL 878

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1878 KNklgmfnkILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQekMKLALEKAmvqgKKRLRGELDIA 1957
Cdd:TIGR02168  879 LN-------ERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ--LELRLEGL----EVRIDNLQERL 945

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1958 KEEKALNLEMkrlAEEKMRLVEGKEtlskgetpetsrqrkmTQVEQELFERKLSLEEkilLHEDRILAMEESEIAKGKLE 2037
Cdd:TIGR02168  946 SEEYSLTLEE---AEALENKIEDDE----------------EEARRRLKRLENKIKE---LGPVNLAAIEEYEELKERYD 1003


                   ....*.
gi 597709775  2038 FTRGQR 2043
Cdd:TIGR02168 1004 FLTAQK 1009

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1597-2199

4.51e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 59.03 E-value: 4.51e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1597 QEEEKLAQEERQLAQEERKlaqayvkiTQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKkwekvaree 1676
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQ--------QKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRAR--------- 65

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1677 ekLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEleelewdMEELswkEEELNQEEGklveekkklaeeeEAL 1756
Cdd:pfam01576   66 --LAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQH-------IQDL---EEQLDEEEA-------------ARQ 120

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1757 AWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKmPEEEERLGRKREQLIEKK------MKLAQKRERWINSME------ 1824
Cdd:pfam01576  121 KLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKER-KLLEERISEFTSNLAEEEekakslSKLKNKHEAMISDLEerlkke 199

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1825 -----ELTKNKMILYQKKNLAQE-----KKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEK 1894
Cdd:pfam01576  200 ekgrqELEKAKRKLEGESTDLQEqiaelQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQED 279

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1895 LTQEK---ETVIKKKEKLAETEKKL-VQVEDSL---AKKQEKLAQEKMKLA-LEKAMVQGKKR----------------- 1949
Cdd:pfam01576  280 LESERaarNKAEKQRRDLGEELEALkTELEDTLdttAAQQELRSKREQEVTeLKKALEEETRSheaqlqemrqkhtqale 359

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1950 -LRGELDIAKEEKAlNLEMKRLAEEKMR--LVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAM 2026
Cdd:pfam01576  360 eLTEQLEQAKRNKA-NLEKAKQALESENaeLQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKL 438

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2027 E-ESEIAKGKLEFTRGQRIfvQGQRKLAKASRKLIKKRESLSKEP-AKLNKILKALQklTRDERKLTQEEI-KMTKMKRA 2103
Cdd:pfam01576  439 QsELESVSSLLNEAEGKNI--KLSKDVSSLESQLQDTQELLQEETrQKLNLSTRLRQ--LEDERNSLQEQLeEEEEAKRN 514

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2104 LfvkERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEviLDDEEEGG 2183
Cdd:pfam01576  515 V---ERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQE--LDDLLVDL 589

                          650
                   ....*....|....*.
gi 597709775  2184 IEEEEVIPFLKRRWRK 2199
Cdd:pfam01576  590 DHQRQLVSNLEKKQKK 605

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

1397-1700

4.60e-08

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 59.31 E-value: 4.60e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1397 QKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRk 1476
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVS- 808

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1477 swkawkeEWEKRLLQEEEKLhqagEKLSPEEEMLQEDKKLKWEEwkqvwenMLSSKSKEQQYKDEEEVTLEEEVSREGEE 1556
Cdd:TIGR02169  809 -------RIEARLREIEQKL----NRLTLEKEYLEKEIQELQEQ-------RIDLKEQIKSIEKEIENLNGKKEELEEEL 870

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1557 KEQQVTEEQrhIQEEHKwaRIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Cdd:TIGR02169  871 EELEAALRD--LESRLG--DLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI 946

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775  1637 FAQK--EETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEEL 1700
Cdd:TIGR02169  947 PEEElsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

207-283

4.61e-08

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 57.34 E-value: 4.61e-08

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 597709775  207 CCFTCFDQGFLYAGNQAGEIQVWSLQQGHPLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWNLTSGSLLRRLE 283
Cdd:cd00200   140 SVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLR 216

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1559-1938

5.34e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.63 E-value: 5.34e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1559 QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKIT---QDDREMAQAEG 1635
Cdd:COG4717    91 AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEelrELEEELEELEA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1636 KFAQKEETLAQRGEKLSQEAEK-LAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELP--QREQNLDWQEK 1712
Cdd:COG4717   171 ELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEaaALEERLKEARL 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1713 E------------LAQELEELEWDMEE--------LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQ 1772
Cdd:COG4717   251 LlliaaallallgLGGSLLSLILTIAGvlflvlglLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGL 330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1773 EEELLIQEKEKLAQHKEKMPEEEERLGRKREQLiekkmKLAQKRERWINSMEEL-TKNKMILYQKKNLAQEKKNLAQEKE 1851
Cdd:COG4717   331 PPDLSPEELLELLDRIEELQELLREAEELEEEL-----QLEELEQEIAALLAEAgVEDEEELRAALEQAEEYQELKEELE 405

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1852 KLAQRKENLLYNKERLtHSKKQLVQVKNKlgmfnkiLAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDS--LAKKQEK 1929
Cdd:COG4717   406 ELEEQLEELLGELEEL-LEALDEEELEEE-------LEELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQE 477


                  ....*....
gi 597709775 1930 LAQEKMKLA 1938
Cdd:COG4717   478 LEELKAELR 486

tolA

cell envelope integrity inner membrane protein TolA; Provisional

1486-1683

7.56e-08

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 57.51 E-value: 7.56e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQvwenmlsSKSKEQQYKdeeevtleeevsreGEEKEQQVTEEQ 1565
Cdd:PRK09510   79 EQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQ-------KKQAEEAAK--------------QAALKQKQAEEA 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1566 RHIQEE--HKWARIHRKRARAEKKRAQEE-RKLAQEEEKLAQEERQLAQEErklAQAYVKITQDDREMAQAEGKFAQKEE 1642
Cdd:PRK09510  138 AAKAAAaaKAKAEAEAKRAAAAAKKAAAEaKKKAEAEAAKKAAAEAKKKAE---AEAAAKAAAEAKKKAEAEAKKKAAAE 214

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 597709775 1643 TLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKG 1683
Cdd:PRK09510  215 AKKKAAAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKA 255

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

1660-2174

7.81e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.21 E-value: 7.81e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELpqrEQNLdwqekelaqelEELEWDMEELSWKEEELNQEE 1739
Cdd:pfam15921  307 QARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEEL---EKQL-----------VLANSELTEARTERDQFSQES 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1740 GKLveekkklaeeeealawqREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLaQKRERW 1819
Cdd:pfam15921  373 GNL-----------------DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEV-QRLEAL 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1820 INSMEELTKNKMilyQKKNLAQEKKNlaQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLtQEK 1899
Cdd:pfam15921  435 LKAMKSECQGQM---ERQMAAIQGKN--ESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASL-QEK 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1900 ETVIKKKEklAETEKKLVQVEDSLakkqeklaQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVE 1979
Cdd:pfam15921  509 ERAIEATN--AEITKLRSRVDLKL--------QELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLV 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1980 GKETLSKGetpetSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRklAKASRKL 2059
Cdd:pfam15921  579 GQHGRTAG-----AMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSER--LRAVKDI 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2060 IKKRESLSKE----PAKLNKILKALQKLTRDERKlTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSE-------- 2127
Cdd:pfam15921  652 KQERDQLLNEvktsRNELNSLSEDYEVLKRNFRN-KSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDghamkvam 730

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775  2128 --------KRSELTKDEKKLARKQRKLANKmrrmiNKEEK-MTEEESKLARKHSEV 2174
Cdd:pfam15921  731 gmqkqitaKRGQIDALQSKIQFLEEAMTNA-----NKEKHfLKEEKNKLSQELSTV 781

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1462-2232

1.13e-07

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 57.75 E-value: 1.13e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1462 KAWDEWKQVHGETRKSWKAWKEEwEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKL------KWEEWKQVWENMLSSKSKE 1535
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQME-LKYLKQYKEKACEIRDQITSKEAQLESSREIvksyenELDPLKNRLKEIEHNLSKI 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1536 QQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERK 1615
Cdd:TIGR00606  265 MKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1616 LAQAYVKIT-QDDREMAQAEGKFAQKEEtLAQRGEKLSQEAEKLAQKRKKLAKKWeKVAREEEKLAKKGGKLAEVKNILA 1694
Cdd:TIGR00606  345 LLVEQGRLQlQADRHQEHIRARDSLIQS-LATRLELDGFERGPFSERQIKNFHTL-VIERQEDEAKTAAQLCADLQSKER 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEG--KLVEEKKKLAEEEEALAWQREKLSEEETKLAq 1772
Cdd:TIGR00606  423 LKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGssDRILELDQELRKAERELSKAEKNSLTETLKK- 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1773 EEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEkkmklaqkrerwinsMEELTKNKMILYQkknlaQEKKNLAQEKEK 1852
Cdd:TIGR00606  502 EVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQ---------------MEMLTKDKMDKDE-----QIRKIKSRHSDE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1853 LAQRKENLLYNK--ERLTHSK-KQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQV--EDSLAKKQ 1927
Cdd:TIGR00606  562 LTSLLGYFPNKKqlEDWLHSKsKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVcgSQDEESDL 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1928 EKLAQEKMKLALEKAMVQGKKRLRGEL--DIAKEEKALNLEMKRLAEEKMRLvegKETLSKGETPETSRQRKMTQVEQEL 2005
Cdd:TIGR00606  642 ERLKEEIEKSSKQRAMLAGATAVYSQFitQLTDENQSCCPVCQRVFQTEAEL---QEFISDLQSKLRLAPDKLKSTESEL 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2006 FERKLSLEEKILLHEDR--ILAMEESEIAKGKleftrgqrifvqgqRKLAKASRKLIKKRESLSKEPAKLNKILKalqKL 2083
Cdd:TIGR00606  719 KKKEKRRDEMLGLAPGRqsIIDLKEKEIPELR--------------NKLQKVNRDIQRLKNDIEEQETLLGTIMP---EE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2084 TRDERKLTQEEIkMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKlaRKQRKLANK---MRRMINKEEKM 2160
Cdd:TIGR00606  782 ESAKVCLTDVTI-MERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQ--HELDTVVSKielNRKLIQDQQEQ 858

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775  2161 TEE-ESKLARKHSEVI-----LDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQvDEVESEEHFSEEMES 2232
Cdd:TIGR00606  859 IQHlKSKTNELKSEKLqigtnLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEK-DQQEKEELISSKETS 935

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1421-2155

1.18e-07

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 57.88 E-value: 1.18e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1421 TKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEwKQVHGETRKSWKAwkEEWEKRLL---QE-EEKL 1496
Cdd:pfam01576    1 TRQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQ-EQLQAETELCAEA--EEMRARLAarkQElEEIL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1497 HQAGEKLSPEEE----MLQEDKKLkweewkqvwenmlsskskEQQYKDEeevtleeevsregeekEQQVTEEQRHIQeeh 1572
Cdd:pfam01576   78 HELESRLEEEEErsqqLQNEKKKM------------------QQHIQDL----------------EEQLDEEEAARQ--- 120

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1573 kwaRIHRKRARAEKK-RAQEERKLAQEEE--KLAQEERQLaqEERkLAQAYVKITqDDREMAQAEGKFAQKEETLAQRGE 1649
Cdd:pfam01576  121 ---KLQLEKVTTEAKiKKLEEDILLLEDQnsKLSKERKLL--EER-ISEFTSNLA-EEEEKAKSLSKLKNKHEAMISDLE 193

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1650 KLSQEAEKLAQKRKKLAKKWEKVARE-EEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEEL 1728
Cdd:pfam01576  194 ERLKKEEKGRQELEKAKRKLEGESTDlQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQI 273

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1729 SWKEEELNQEEGklveekkklaeEEEALAWQREKLSEE----ETKL-------AQEEELLIQEKEKLAQHKEKMpEEEER 1797
Cdd:pfam01576  274 SELQEDLESERA-----------ARNKAEKQRRDLGEElealKTELedtldttAAQQELRSKREQEVTELKKAL-EEETR 341

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1798 lgRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQ-KKNLAQEKKNLAQEKEKLAQRKENLLYNKERLthsKKQLVQ 1876
Cdd:pfam01576  342 --SHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKaKQALESENAELQAELRTLQQAKQDSEHKRKKL---EGQLQE 416

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1877 VKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLV-------QVEDSLAKKQEKLAQE-KMKLALekamvqgKK 1948
Cdd:pfam01576  417 LQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIklskdvsSLESQLQDTQELLQEEtRQKLNL-------ST 489

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1949 RLRgeldiAKEEKALNLeMKRLAEEkmrlVEGKETLskgetpetsrQRKMTQVEQELFERKLSLEEKI----LLHEDRIL 2024
Cdd:pfam01576  490 RLR-----QLEDERNSL-QEQLEEE----EEAKRNV----------ERQLSTLQAQLSDMKKKLEEDAgtleALEEGKKR 549

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2025 AMEESEIAKGKLEFTrgqrifVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEikmtKMKRAL 2104
Cdd:pfam01576  550 LQRELEALTQQLEEK------AAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEE----KAISAR 619

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|..
gi 597709775  2105 FVKER-RLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMIN 2155
Cdd:pfam01576  620 YAEERdRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVS 671

PRK12704

phosphodiesterase; Provisional

1577-1695

1.86e-07

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 56.71 E-value: 1.86e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1577 IHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656
Cdd:PRK12704   66 IHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELE 145

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 597709775 1657 KLA-----QKRKKLAKKWEKVAREE--------EKLAKKGGKlAEVKNILAQ 1695
Cdd:PRK12704  146 RISgltaeEAKEILLEKVEEEARHEaavlikeiEEEAKEEAD-KKAKEILAQ 196

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1617-2271

2.09e-07

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 56.98 E-value: 2.09e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1617 AQAYVKITQDDREMAQAEGKFAQKEETLAQRgekLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILaQK 1696
Cdd:TIGR00606  181 ATRYIKALETLRQVRQTQGQKVQEHQMELKY---LKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRL-KE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1697 VEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQ-EEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEE 1775
Cdd:TIGR00606  257 IEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQgTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERR 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1776 LLIQEKEKLAQHKEKMPEEEERL---GRKREQLIekkMKLAQKRErwinsMEELTKNKMILYQKKNLAQEKKNLAQEKEK 1852
Cdd:TIGR00606  337 LLNQEKTELLVEQGRLQLQADRHqehIRARDSLI---QSLATRLE-----LDGFERGPFSERQIKNFHTLVIERQEDEAK 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1853 LAQRKENLLYNKERLthSKKQLVQVKNKLGMFNKILAQVEEKLTQEKET---VIKKKEKLAETEKKLVQVEDSLAKKQEK 1929
Cdd:TIGR00606  409 TAAQLCADLQSKERL--KQEQADEIRDEKKGLGRTIELKKEILEKKQEElkfVIKELQQLEGSSDRILELDQELRKAERE 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1930 LAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEgKETLSKGETPETSRQRKM-TQVEQEL--- 2005
Cdd:TIGR00606  487 LSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQ-MEMLTKDKMDKDEQIRKIkSRHSDELtsl 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2006 ---FERKLSLEEKILLHEDRILAMEEsEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESL------SKEPAKLNKI 2076
Cdd:TIGR00606  566 lgyFPNKKQLEDWLHSKSKEINQTRD-RLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERL 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2077 LKALQKLTRDerkltqeeIKMTKMKRALFVK--ERRLSIEQSKLDIKEWDFsekrseltKDEKKLARKQRKLANKMRRMI 2154
Cdd:TIGR00606  645 KEEIEKSSKQ--------RAMLAGATAVYSQfiTQLTDENQSCCPVCQRVF--------QTEAELQEFISDLQSKLRLAP 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2155 NKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEV--IPFLKRRWRK-RKEAKRGDKPKEKFSSQVDEVESEEHFSEE-- 2229
Cdd:TIGR00606  709 DKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEkeIPELRNKLQKvNRDIQRLKNDIEEQETLLGTIMPEEESAKVcl 788

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 597709775  2230 -----MESLLDELEKQESLSSEEEEEREEEEEREEEEEREEEEERKE 2271
Cdd:TIGR00606  789 tdvtiMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQ 835

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1401-1656

2.83e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 56.29 E-value: 2.83e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1401 KQGRKAVQKERKVGKIKREMTKEE------RDMSEEVEEMATLEEKVVKQEGKLVMIERTpswqdwKKAWDEWKQVHGET 1474
Cdd:pfam17380  338 EQERMAMERERELERIRQEERKRElerirqEEIAMEISRMRELERLQMERQQKNERVRQE------LEAARKVKILEEER 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1475 RKSWKAWKEEWEKRLLQEEEKLHQAGEKLspEEEMLQEDKKLKWEEW-KQVWENMLSSKSKEQQYKdeeevtleeEVSRE 1553
Cdd:pfam17380  412 QRKIQQQKVEMEQIRAEQEEARQREVRRL--EEERAREMERVRLEEQeRQQQVERLRQQEEERKRK---------KLELE 480

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1554 GEEKEQQVTEEQRHI-----QEEHKWARIHRKRARAEKKRAQEERKLA---QEEEKLAQEER--QLAQEERKLAQAYVKI 1623
Cdd:pfam17380  481 KEKRDRKRAEEQRRKilekeLEERKQAMIEEERKRKLLEKEMEERQKAiyeEERRREAEEERrkQQEMEERRRIQEQMRK 560

                          250       260       270
                   ....*....|....*....|....*....|...
gi 597709775  1624 TQDDREMAQAegkFAQKEETLAQRGEKLSQEAE 1656
Cdd:pfam17380  561 ATEERSRLEA---MEREREMMRQIVESEKARAE 590

HCR

pfam07111

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...

1411-1873

4.99e-07

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.

Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 55.53 E-value: 4.99e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1411 RKVGKIKR-EMTKEERDM--------SEEVEEMATLEEKVVKQEGKLVMIE-RTPSWQDWKKAWDEWKQVHGETRKSWKA 1480
Cdd:pfam07111  184 KRAGEAKQlAEAQKEAELlrkqlsktQEELEAQVTLVESLRKYVGEQVPPEvHSQTWELERQELLDTMQHLQEDRADLQA 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1481 WKEEWEKRL--------LQEEE--KLHQAGEKLSPEEEMLQEDKKLKWEEwkQVWENMLSSKSKEQQYKDEEEVTLEEEV 1550
Cdd:pfam07111  264 TVELLQVRVqslthmlaLQEEEltRKIQPSDSLEPEFPKKCRSLLNRWRE--KVFALMVQLKAQDLEHRDSVKQLRGQVA 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1551 SREGEEKEQqvTEEQRHIQE--EHKWARIHRKRARAekKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDdr 1628
Cdd:pfam07111  342 ELQEQVTSQ--SQEQAILQRalQDKAAEVEVERMSA--KGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQI-- 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1629 emaQAEGKFAQKEETLAQ---RGEKLSQEAEKLAQKRKKLAKKWeKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQ 1705
Cdd:pfam07111  416 ---WLETTMTRVEQAVARipsLSNRLSYAVRKVHTIKGLMARKV-ALAQLRQESCPPPPPAPPVDADLSLELEQLREERN 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1706 NLDWQEKELAQELEELEWDMEE--------LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEeelL 1777
Cdd:pfam07111  492 RLDAELQLSAHLIQQEVGRAREqgeaerqqLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQE---L 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1778 IQEKEKLAQH-KEKMPEEEERLgrkREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEK---- 1852
Cdd:pfam07111  569 TQQQEIYGQAlQEKVAEVETRL---REQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEARKeegq 645

                          490       500
                   ....*....|....*....|..
gi 597709775  1853 -LAQRKENLLYNKERLTHSKKQ 1873
Cdd:pfam07111  646 rLARRVQELERDKNLMLATLQQ 667

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

1482-2165

5.01e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.83 E-value: 5.01e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1482 KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQE-DKKLKW--EEWKQVWENMLSSKSKEQQYKDEEEVTLEeevsregeeKE 1558
Cdd:TIGR02168  276 VSELEEEIEELQKELYALANEISRLEQQKQIlRERLANleRQLEELEAQLEELESKLDELAEELAELEE---------KL 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1559 QQVTEEQRHIQEEHKwarihrkraRAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFA 1638
Cdd:TIGR02168  347 EELKEELESLEAELE---------ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1639 QKEETLAQRGEKLSQEA-----EKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDwqeke 1713
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAElkelqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD----- 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1714 laqeleeLEWDMEElswkEEELNQEEGKLVEEKKKLAEEEEALAWQREKlSEEETKLAQEEEL-------LIQEKEKLAQ 1786
Cdd:TIGR02168  493 -------SLERLQE----NLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALggrlqavVVENLNAAKK 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1787 HKEKMpeEEERLGRkREQLIEKKMKLAQKRerwINSMEELTKNKMILYQKKNLAQEKK-----------------NLAQe 1849
Cdd:TIGR02168  561 AIAFL--KQNELGR-VTFLPLDSIKGTEIQ---GNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvdDLDN- 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1850 keklAQRKENLLYNKERLTHSKKQLV---------QVKNKLGMFNKI--LAQVEEKLTQEKETVIKKKEKLAETEKKLVQ 1918
Cdd:TIGR02168  634 ----ALELAKKLRPGYRIVTLDGDLVrpggvitggSAKTNSSILERRreIEELEEKIEELEEKIAELEKALAELRKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1919 VEDSLAKKQEKLAQEKMKLALEKAMVQgkkrlRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKM 1998
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLA-----RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1999 TQVEQELFERKLSLEEkillhEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRK---LIKKRESLSKEPAKLNK 2075
Cdd:TIGR02168  785 EELEAQIEQLKEELKA-----LREALDELRAELTLLNEEAANLRERLESLERRIAATERRledLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2076 ILKALQKLTRD-ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLAN-KMRRM 2153
Cdd:TIGR02168  860 EIEELEELIEElESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGlEVRID 939

                          730
                   ....*....|..
gi 597709775  2154 iNKEEKMTEEES 2165
Cdd:TIGR02168  940 -NLQERLSEEYS 950

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1608-1986

6.10e-07

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 55.41 E-value: 6.10e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1608 QLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLakkwEKVAREEEKLAKKGGKLA 1687
Cdd:TIGR04523  315 ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEI----EKLKKENQSYKQEIKNLE 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1688 EVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEegklveekkklaeeeealawqREKLSEEE 1767
Cdd:TIGR04523  391 SQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSE---------------------IKDLTNQD 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1768 TKLaqeeELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEEltknkmilyQKKNLAQEKKNLA 1847
Cdd:TIGR04523  450 SVK----ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNE---------EKKELEEKVKDLT 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1848 QEKEKLAQRKENLlyNKERLTHSKKqLVQVKNKLGMFNKILAQveEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ 1927
Cdd:TIGR04523  517 KKISSLKEKIEKL--ESEKKEKESK-ISDLEDELNKDDFELKK--ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELI 591

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1928 EKLAQEKMKLALEKAMVQGKK-RLRGELDIAKEEKalnlemKRLAEEKMRLVEGKETLSK 1986
Cdd:TIGR04523  592 DQKEKEKKDLIKEIEEKEKKIsSLEKELEKAKKEN------EKLSSIIKNIKSKKNKLKQ 645

TolA

COG3064

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

1557-1980

6.18e-07

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 55.05 E-value: 6.18e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1557 KEQQVTEEQRHIQEEHK------WARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREM 1630
Cdd:COG3064    49 AKRQAEEEAREAKAEAEqraaelAAEAAKKLAEAEKAAAEAEKKAAAEKAKAAKEAEAAAAAEKAAAAAEKEKAEEAKRK 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1631 AQAEGKF-AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKggKLAEVKNILAQKVEELPQREQNLDW 1709
Cdd:COG3064   129 AEEEAKRkAEEERKAAEAEAAAKAEAEAARAAAAAAAAAAAAAARAAAGAAAA--LVAAAAAAVEAADTAAAAAAALAAA 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1710 QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKE 1789
Cdd:COG3064   207 AAAAAADAALLALAVAARAAAASREAALAAVEATEEAALGGAEEAADLAAVGVLGAALAAAAAGAAALSSGLVVVAAALA 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1790 KMPEEEERLGRkREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTH 1869
Cdd:COG3064   287 GLAAAAAGLVL-DDSAALAAELLGAVAAEEAVLAAAAAAGALVVRGGGAASLEAALSLLAAGAAAAAAGAGALATGALGD 365

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1870 SKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKkeKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKR 1949
Cdd:COG3064   366 ALAAEAAGALLLGKLADVEEAAGAGILAAAGGGGLL--GLRLDLGAALLEAASAVELRVLLALAGAAGAVVALLVKLVAD 443

                         410       420       430
                  ....*....|....*....|....*....|.
gi 597709775 1950 LRGELDIAKEEKALNLEMKRLAEEKMRLVEG 1980
Cdd:COG3064   444 LAGGLVGIGKALTGDADALLGILKAVALDGG 474

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

1762-2237

6.21e-07

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 55.41 E-value: 6.21e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1762 KLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRErwinsmeELTKNKMILYQKKNLAQ 1841
Cdd:TIGR04523  219 QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK-------ELEQNNKKIKELEKQLN 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1842 EKKNlaqEKEKLAQRKENLLYN--KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETV-------IKKKEKLAET 1912
Cdd:TIGR04523  292 QLKS---EISDLNNQKEQDWNKelKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELtnsesenSEKQRELEEK 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1913 EKKLVQVE---DSLAKKQEKLAQEKMKLALEkamVQGKKRLRGELD--IAKEEKALNL---EMKRLAEEKMRL------V 1978
Cdd:TIGR04523  369 QNEIEKLKkenQSYKQEIKNLESQINDLESK---IQNQEKLNQQKDeqIKKLQQEKELlekEIERLKETIIKNnseikdL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1979 EGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIakgkLEFTRGQRIFVQGQRKLAKASRK 2058
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL----KKLNEEKKELEEKVKDLTKKISS 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2059 LIKKRESLSKEPAKLNKILKALQ-KLTRDERKLTQEEIKMTKMKRALFVKERRLSIE---------QSKLDIKEWDFSE- 2127
Cdd:TIGR04523  522 LKEKIEKLESEKKEKESKISDLEdELNKDDFELKKENLEKEIDEKNKEIEELKQTQKslkkkqeekQELIDQKEKEKKDl 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2128 ---------KRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEE------ESKLARKHSEVILDDEEEGGIEEEEVI-- 2190
Cdd:TIGR04523  602 ikeieekekKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEvkqikeTIKEIRNKWPEIIKKIKESKTKIDDIIel 681

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775  2191 --PFLKRRWRKRKEA-----KRGDKPK--EKFSSQVDEVESEEHFSEEMESLLDEL 2237
Cdd:TIGR04523  682 mkDWLKELSLHYKKYitrmiRIKDLPKleEKYKEIEKELKKLDEFSKELENIIKNF 737

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

1401-2002

6.67e-07

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 55.44 E-value: 6.67e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1401 KQGRKAVQKERKVGKIKREMTKEERDMS--EEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAW-----DEWKQVHGE 1473
Cdd:TIGR00606  461 KELQQLEGSSDRILELDQELRKAERELSkaEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQlnhhtTTRTQMEML 540

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1474 TRKSWKAWKEEWEKRLLQEEEKLHQAG-----EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEE 1548
Cdd:TIGR00606  541 TKDKMDKDEQIRKIKSRHSDELTSLLGyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQ 620

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1549 EVSRegeekEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQeerkLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDR 1628
Cdd:TIGR00606  621 LSSY-----EDKLFDVCGSQDEESDLERLKEEIEKSSKQRAM----LAGATAVYSQFITQLTDENQSCCPVCQRVFQTEA 691

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1629 EMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKkggKLAEVKNILAQKVEELPQREQNLD 1708
Cdd:TIGR00606  692 ELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEK---EIPELRNKLQKVNRDIQRLKNDIE 768

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1709 WQEKE------LAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQ-----REKLSEEETKLAQEEEL- 1776
Cdd:TIGR00606  769 EQETLlgtimpEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQqvnqeKQEKQHELDTVVSKIELn 848

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1777 --LIQEKEKLAQHKEKMPEEeerLGRKREQLIEKkmklAQKRERWINSMEELTKNKMILYQK-KNLAQEKKNLAQEKEKL 1853
Cdd:TIGR00606  849 rkLIQDQQEQIQHLKSKTNE---LKSEKLQIGTN----LQRRQQFEEQLVELSTEVQSLIREiKDAKEQDSPLETFLEKD 921

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1854 AQRKENLLYNKE---RLTHSKKQLV--QVKNKLG----MFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL- 1923
Cdd:TIGR00606  922 QQEKEELISSKEtsnKKAQDKVNDIkeKVKNIHGymkdIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMr 1001

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1924 --------AKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALnLEMKRL---AEEKMRLVEGKETLSKGETPET 1992
Cdd:TIGR00606 1002 lmrqdidtQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQV-LQMKQEhqkLEENIDLIKRNHVLALGRQKGY 1080

                          650
                   ....*....|
gi 597709775  1993 SRQRKMTQVE 2002
Cdd:TIGR00606 1081 EKEIKHFKKE 1090

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1583-1900

6.96e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 55.13 E-value: 6.96e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1583 RAEKKRAQEERKLAQEEEKLAQEERQLAQE---ERKLAQAYvkiTQDDREMAQAEGKFAQKEETLAQRgeklSQEAEKLA 1659
Cdd:pfam17380  282 KAVSERQQQEKFEKMEQERLRQEKEEKAREverRRKLEEAE---KARQAEMDRQAAIYAEQERMAMER----ERELERIR 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1660 QKRKKlaKKWEKVAREEekLAKKGGKLAEVKNILAQKVEELPQREQNLD------WQEKELAQELEELEWDMEELSWKEE 1733
Cdd:pfam17380  355 QEERK--RELERIRQEE--IAMEISRMRELERLQMERQQKNERVRQELEaarkvkILEEERQRKIQQQKVEMEQIRAEQE 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1734 ELNQEEGKLVEEKKKLaeeeealawQREKLSEEETKLAQEEELLIQEKE-----KLAQHKEK----MPEEEERlgrkreQ 1804
Cdd:pfam17380  431 EARQREVRRLEEERAR---------EMERVRLEEQERQQQVERLRQQEEerkrkKLELEKEKrdrkRAEEQRR------K 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1805 LIEKKMKlaqkrERWINSMEELTKNKMIlyqKKNLAQEKKNLAQEKEKL----AQRKENLLYNKERLTHSKKQLVQVKNK 1880
Cdd:pfam17380  496 ILEKELE-----ERKQAMIEEERKRKLL---EKEMEERQKAIYEEERRReaeeERRKQQEMEERRRIQEQMRKATEERSR 567

                          330       340
                   ....*....|....*....|...
gi 597709775  1881 LGMFNK---ILAQVEEKLTQEKE 1900
Cdd:pfam17380  568 LEAMERereMMRQIVESEKARAE 590

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

373-635

7.09e-07

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 53.49 E-value: 7.09e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  373 AVDWAYDPGkeelFVATGSS--EVLVFDTTRCPCPAKYLLGTSPnsqdFVQCLAYGHFNLgrgleglIFSGHQSGVIRVL 450
Cdd:cd00200    14 CVAFSPDGK----LLATGSGdgTIKVWDLETGELLRTLKGHTGP----VRDVAASADGTY-------LASGSSDKTIRLW 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  451 SQHSCARLEKF-MHFGAVLALSTLsggifggQGNSLLCSyGMDDYVHLSEAVLDGVKVQLRPlasilssCHLthlillpK 529
Cdd:cd00200    79 DLETGECVRTLtGHTSYVSSVAFS-------PDGRILSS-SSRDKTIKVWDVETGKCLTTLR-------GHT-------D 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  530 SVgaitetNCLRLWKFHDFLSSGSQNG---------LKFIETLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWDFH-GR 599
Cdd:cd00200   137 WV------NSVAFSPDGTFVASSSQDGtiklwdlrtGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLStGK 210

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 597709775  600 LIGILDSslHFGPVCFandrgdllVTFNQSLYLVSC 635
Cdd:cd00200   211 CLGTLRG--HENGVNS--------VAFSPDGYLLAS 236

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1579-1831

7.10e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.31 E-value: 7.10e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQrgekLSQEAEKL 1658
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDDL 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1659 AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDwqeKELAQELEELEWDMEELsWKEEELNQE 1738
Cdd:COG4913   688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE---AAEDLARLELRALLEER-FAAALGDAV 763

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1739 EGKLVeekkklaeeeealAWQREKLSEEETKLAQEEELLIqekEKLAQHKEKMPEEEERLG----------RKREQLIEK 1808
Cdd:COG4913   764 ERELR-------------ENLEERIDALRARLNRAEEELE---RAMRAFNREWPAETADLDadleslpeylALLDRLEED 827

                         250       260
                  ....*....|....*....|...
gi 597709775 1809 kmKLAQKRERWINSMEELTKNKM 1831
Cdd:COG4913   828 --GLPEYEERFKELLNENSIEFV 848

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

1760-2171

1.62e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 54.07 E-value: 1.62e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1760 REKLSEEETKLAQEEELLIQE----KEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQ 1835
Cdd:pfam12128  289 NQLLRTLDDQWKEKRDELNGElsaaDAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTG 368

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1836 KKNLAQEKKNLAQEKEKLaQRKENLLYNKERLTHSK----KQLVQVKNKL-GMFNKILAQVEEKLTQEKETVIKKKEKLA 1910
Cdd:pfam12128  369 KHQDVTAKYNRRRSKIKE-QNNRDIAGIKDKLAKIReardRQLAVAEDDLqALESELREQLEAGKLEFNEEEYRLKSRLG 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1911 ETEkklVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEE-----------KALNLEMKRLAEEKMRLVE 1979
Cdd:pfam12128  448 ELK---LRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELrqarkrrdqasEALRQASRRLEERQSALDE 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1980 GKETLSKGETPETSRQRKMTQVEQELFERKLSLEekiLLHEDRILAMEESEIAKGKLEF----TRGQRIFV--------Q 2047
Cdd:pfam12128  525 LELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPE---LLHRTDLDPEVWDGSVGGELNLygvkLDLKRIDVpewaaseeE 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2048 GQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRderkltqeeiKMTKMKRALfvkerrlsiEQSKLDIKEWdFSE 2127
Cdd:pfam12128  602 LRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASR----------EETFARTAL---------KNARLDLRRL-FDE 661

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 597709775  2128 KRSELTKDEKKLARKQRKlANKMRRMINKEEKMTEEESKLARKH 2171
Cdd:pfam12128  662 KQSEKDKKNKALAERKDS-ANERLNSLEAQLKQLDKKHQAWLEE 704

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1575-1917

2.01e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 52.98 E-value: 2.01e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1575 ARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAyvkitqdDREMAQAEGKFAQKEETLAQRGEKLSQE 1654
Cdd:COG4372     6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQL-------REELEQAREELEQLEEELEQARSELEQL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1655 AEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEvkniLAQKVEELPQREQNLDWQEKELAQELEELEWDMEElswKEEE 1734
Cdd:COG4372    79 EEELEELNEQLQAAQAELAQAQEELESLQEEAEE----LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAE---REEE 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETK--LAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKL 1812
Cdd:COG4372   152 LKELEEQLESLQEELAALEQELQALSEAEAEQALDelLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKL 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1813 AQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVE 1892
Cdd:COG4372   232 GLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIG 311

                         330       340
                  ....*....|....*....|....*
gi 597709775 1893 EKLTQEKETVIKKKEKLAETEKKLV 1917
Cdd:COG4372   312 ALEDALLAALLELAKKLELALAILL 336

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

207-272

2.90e-06

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 51.57 E-value: 2.90e-06

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775  207 CCFTCF--DQGFLYAGNQAGEIQVWSLQQGHPLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWN 272
Cdd:cd00200   222 VNSVAFspDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

1563-1690

3.30e-06

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 52.91 E-value: 3.30e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1563 EEQRHIQEEhKWARIHRKRARAEKKRaqeeRKLAQEEEKLAQEERQLAQEERKLAQAYVKitqddreMAQAEGKFAQKEE 1642
Cdd:PRK00409  526 EELERELEQ-KAEEAEALLKEAEKLK----EELEEKKEKLQEEEDKLLEEAEKEAQQAIK-------EAKKEADEIIKEL 593

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 597709775 1643 TLAQRGEKLSQEAEKLAQKRKKLAKKWEKVareEEKLAKKGGKLAEVK 1690
Cdd:PRK00409  594 RQLQKGGYASVKAHELIEARKRLNKANEKK---EKKKKKQKEKQEELK 638

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

1589-1818

4.12e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 51.75 E-value: 4.12e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKk 1668
Cdd:COG3883    12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1669 wekVAREeekLAKKGGKLAEVKNIL-AQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKK 1747
Cdd:COG3883    91 ---RARA---LYRSGGSVSYLDVLLgSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKA 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 597709775 1748 KLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818
Cdd:COG3883   165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235

Caldesmon

pfam02029

Caldesmon;

1406-1682

4.41e-06

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 52.18 E-value: 4.41e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1406 AVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKlVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEW 1485
Cdd:pfam02029    7 AARERRRRAREERRRQKEEEEPSGQVTESVEPNEHNSYEEDS-ELKPSGQGGLDEEEAFLDRTAKREERRQKRLQEALER 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1486 EKRLLQE--EEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTE 1563
Cdd:pfam02029   86 QKEFDPTiaDEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEEEGEEEEDKSEE 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1564 EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFA----- 1638
Cdd:pfam02029  166 AEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTKRRQGGLSQSQEREEEAevfle 245

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775  1639 ---QKEETLAQRGEKLSQEAEKLAQKRKKLA---------KKWEKVAREEEKLAKK 1682
Cdd:pfam02029  246 aeqKLEELRRRRQEKESEEFEKLRQKQQEAEleleelkkkREERRKLLEEEEQRRK 301

PRK02224

DNA double-strand break repair Rad50 ATPase;

1575-2089

4.45e-06

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 52.35 E-value: 4.45e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1575 ARIHRKRARAEKKRAQEERKlAQEEEKLAQE-ERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLsQ 1653
Cdd:PRK02224  174 ARLGVERVLSDQRGSLDQLK-AQIEEKEEKDlHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR-E 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1654 EAEKLAQKRKKLAKKWEKVAREEEKlakkggklaevkniLAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEE 1733
Cdd:PRK02224  252 ELETLEAEIEDLRETIAETEREREE--------------LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARRE 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1734 ELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLiqeKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLA 1813
Cdd:PRK02224  318 ELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEEL---REEAAELESELEEAREAVEDRREEIEELEEEIE 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1814 QKRERWINS----------MEELTKNKMILYQKKN-----LAQEKKNLAQEKEKLAQRK--------------ENLLYNK 1864
Cdd:PRK02224  395 ELRERFGDApvdlgnaedfLEELREERDELREREAeleatLRTARERVEEAEALLEAGKcpecgqpvegsphvETIEEDR 474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1865 ERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKEtVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQ---EKMKL---A 1938
Cdd:PRK02224  475 ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEELIAERRETIEEKRERAEElreRAAELeaeA 553

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1939 LEKAMVQGKKRLRGElDIAKEEKALNLEMKRLAEEKMRLVEGKETLSK----GETPETSRQRKMTQVEQELfERKLSLEE 2014
Cdd:PRK02224  554 EEKREAAAEAEEEAE-EAREEVAELNSKLAELKERIESLERIRTLLAAiadaEDEIERLREKREALAELND-ERRERLAE 631

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775 2015 KillhEDRILAMEEsEIAKGKLEFTRGQRI-FVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLtRDERK 2089
Cdd:PRK02224  632 K----RERKRELEA-EFDEARIEEAREDKErAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEEL-RERRE 701

PRK12705

hypothetical protein; Provisional

1595-1703

7.24e-06

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 51.63 E-value: 7.24e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1595 LAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRgEKLSQEAEKLAQKRKKLAKKWEKVAR 1674
Cdd:PRK12705   24 LLKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRER-EELQREEERLVQKEEQLDARAEKLDN 102

                          90       100
                  ....*....|....*....|....*....
gi 597709775 1675 EEEKLAKKGGKLAEVKNILAQKVEELPQR 1703
Cdd:PRK12705  103 LENQLEEREKALSARELELEELEKQLDNE 131

tolA_full

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

1526-1696

8.22e-06

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 50.61 E-value: 8.22e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1526 ENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEkkrAQEERKLAQEEEKLAQE 1605
Cdd:TIGR02794   78 EEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAE---AEAERKAKEEAAKQAEE 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1606 ERQL-AQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGE----KLSQEAEKLAQKRKKLAKKWEKVAREEEKLA 1680
Cdd:TIGR02794  155 EAKAkAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEaakaKAAAEAAAKAEAEAAAAAAAEAERKADEAEL 234

                          170
                   ....*....|....*.
gi 597709775  1681 KKGGKLAEVKNILAQK 1696
Cdd:TIGR02794  235 GDIFGLASGSNAEKQG 250

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

1558-2051

8.78e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.66 E-value: 8.78e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1558 EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQL 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1638 AQKEETLAQRGEKLSQEAEK--------------LAQKRKKLAKKWEKVAREE--------------------------- 1676
Cdd:pfam15921  380 QKLLADLHKREKELSLEKEQnkrlwdrdtgnsitIDHLRRELDDRNMEVQRLEallkamksecqgqmerqmaaiqgknes 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1677 -EKLAKKGGKLAEVKNILAQKVEELPQREQNLDwqekELAQELEELEWDMEELSWKEEELNQEEGKLveekkKLAEEEEA 1755
Cdd:pfam15921  460 lEKVSSLTAQLESTKEMLRKVVEELTAKKMTLE----SSERTVSDLTASLQEKERAIEATNAEITKL-----RSRVDLKL 530

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1756 LAWQREKLSEEETKLAQEE----ELLIQEKEK----LAQHKEKMPEEEERLGRKREQLIEKKMKLaqkrERWINSMEELT 1827
Cdd:pfam15921  531 QELQHLKNEGDHLRNVQTEcealKLQMAEKDKvieiLRQQIENMTQLVGQHGRTAGAMQVEKAQL----EKEINDRRLEL 606

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1828 KNKMILYQKKN-----LAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLV-QVKNKLGMFNKILAQVE------EKL 1895
Cdd:pfam15921  607 QEFKILKDKKDakireLEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLnEVKTSRNELNSLSEDYEvlkrnfRNK 686

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1896 TQEKETVIKK-KEKLAETEKKLVQVEDSLaKKQEKLAQEKMKLALekAMVQGKKRLRGELDiAKEEKALNLE--MKRLAE 1972
Cdd:pfam15921  687 SEEMETTTNKlKMQLKSAQSELEQTRNTL-KSMEGSDGHAMKVAM--GMQKQITAKRGQID-ALQSKIQFLEeaMTNANK 762

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 597709775  1973 EKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKIllhedrilAMEESEIAKGKLEFTRGQRIfVQGQRK 2051
Cdd:pfam15921  763 EKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKV--------ANMEVALDKASLQFAECQDI-IQRQEQ 832

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1575-2095

8.79e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.31 E-value: 8.79e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1575 ARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEgkfaqkeetlaQRGEKLSQE 1654
Cdd:COG4717    49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELE-----------AELEELREE 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1655 AEKLAQKrKKLAKKWEKVAREEEKLAKKGGKLAEVKnilaQKVEELPQREqnldwqekelaqeleelewdmEELSWKEEE 1734
Cdd:COG4717   118 LEKLEKL-LQLLPLYQELEALEAELAELPERLEELE----ERLEELRELE---------------------EELEELEAE 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1735 LNQEEGKLVeekKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKmKLAQ 1814
Cdd:COG4717   172 LAELQEELE---ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE-RLKE 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1815 KRERW--INSMEELTKNKMILYQKKN------------LAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNK 1880
Cdd:COG4717   248 ARLLLliAAALLALLGLGGSLLSLILtiagvlflvlglLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAA 327

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1881 LGMfnkilaqveeKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEE 1960
Cdd:COG4717   328 LGL----------PPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEY 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1961 KALNLEMKRLAEEKMRLVEGKETLSKGETPEtsrqrkmtQVEQELFErklsLEEKILLHEDRILAMEEsEIA--KGKLEF 2038
Cdd:COG4717   398 QELKEELEELEEQLEELLGELEELLEALDEE--------ELEEELEE----LEEELEELEEELEELRE-ELAelEAELEQ 464

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 597709775 2039 TRGQRIFVQGQRKLAKASRKLikkrESLSKEPAKLNKILKALQKLTRDERKLTQEEI 2095
Cdd:COG4717   465 LEEDGELAELLQELEELKAEL----RELAEEWAALKLALELLEEAREEYREERLPPV 517

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1559-1878

9.10e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 50.67 E-value: 9.10e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1559 QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFA 1638
Cdd:COG4372    41 DKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEEL 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1639 QKE-ETLAQRGEKLSQEAEKL----AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV--EELPQREQNLDWQE 1711
Cdd:COG4372   121 QKErQDLEQQRKQLEAQIAELqseiAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQAldELLKEANRNAEKEE 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1712 KELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQ-EKEKLAQHKEK 1790
Cdd:COG4372   201 ELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILvEKDTEEEELEI 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1791 MPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHS 1870
Cdd:COG4372   281 AALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLS 360


                  ....*...
gi 597709775 1871 KKQLVQVK 1878
Cdd:COG4372   361 KGAEAGVA 368

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1854-2192

1.06e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 50.67 E-value: 1.06e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1854 AQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQE 1933
Cdd:COG4372    27 AALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1934 KmklalekamvQGKKRLRGELdiakeeKALNLEMKRLAEEKMRLvegKETLSKGETPETSRQRKMTQVEQELFERKLSLE 2013
Cdd:COG4372   107 Q----------EEAEELQEEL------EELQKERQDLEQQRKQL---EAQIAELQSEIAEREEELKELEEQLESLQEELA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2014 EkiLLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQE 2093
Cdd:COG4372   168 A--LEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELE 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2094 EIKMT-------KMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESK 2166
Cdd:COG4372   246 EDKEElleevilKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELA 325

                         330       340
                  ....*....|....*....|....*.
gi 597709775 2167 LARKHSEVILDDEEEGGIEEEEVIPF 2192
Cdd:COG4372   326 KKLELALAILLAELADLLQLLLVGLL 351

tolA

cell envelope integrity inner membrane protein TolA; Provisional

1561-1690

1.13e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 50.58 E-value: 1.13e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1561 VTEEQRHIQEEHKWARihRKRARAEKKRAQEERKLAQEEEKLAQEERQlAQEERKLAQAYVKITQDDREMAQAEGKfaQK 1640
Cdd:PRK09510   60 VVEQYNRQQQQQKSAK--RAEEQRKKKEQQQAEELQQKQAAEQERLKQ-LEKERLAAQEQKKQAEEAAKQAALKQK--QA 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 597709775 1641 EETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVK 1690
Cdd:PRK09510  135 EEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAK 184

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1559-1709

1.16e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 1.16e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1559 QQVTEEQRHIQ--EEHKWARI-----HRKRARAEKKRAQEER---KLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDR 1628
Cdd:COG4913   641 DALQERREALQrlAEYSWDEIdvasaEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEK 720

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1629 EMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELpQREQNLD 1708
Cdd:COG4913   721 ELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA-MRAFNRE 799


                  .
gi 597709775 1709 W 1709
Cdd:COG4913   800 W 800

PRK12705

hypothetical protein; Provisional

1557-1682

1.28e-05

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 50.48 E-value: 1.28e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1557 KEQQVTEEQRHIQEEHKWARIHRKRARAEKK------RAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQddrem 1630
Cdd:PRK12705   28 RQRLAKEAERILQEAQKEAEEKLEAALLEAKelllreRNQQRQEARREREELQREEERLVQKEEQLDARAEKLDN----- 102

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 597709775 1631 aqaegkfaqKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKK 1682
Cdd:PRK12705  103 ---------LENQLEEREKALSARELELEELEKQLDNELYRVAGLTPEQARK 145

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1759-2251

1.41e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 1.41e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEkmpEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKnkmILYQKKN 1838
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELA---ELEAELEELRLELEELELELEEAQAEEYELLAELAR---LEQDIAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1839 LAQEKKNLAQEKEKLAQRKENLlynKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQ 1918
Cdd:COG1196   307 LEERRRELEERLEELEEELAEL---EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1919 VEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKEtlskgetpETSRQRKM 1998
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA--------AEEEAELE 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1999 TQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKReslskepaklnKILK 2078
Cdd:COG1196   456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR-----------GLAG 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2079 ALQKLTRDERKLTQEEIkmtkmkralfvkERRLSIEQSKLDIKEWDFSEKRSELTkdEKKLARKQRKLANKMRRminkeE 2158
Cdd:COG1196   525 AVAVLIGVEAAYEAALE------------AALAAALQNIVVEDDEVAAAAIEYLK--AAKAGRATFLPLDKIRA-----R 585

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2159 KMTEEESKLARKHSEVIL--DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLdE 2236
Cdd:COG1196   586 AALAAALARGAIGAAVDLvaSDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT-G 664

                         490
                  ....*....|....*
gi 597709775 2237 LEKQESLSSEEEEER 2251
Cdd:COG1196   665 GSRRELLAALLEAEA 679

tolA_full

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

1574-1703

1.61e-05

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 49.84 E-value: 1.61e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1574 WARIHRKRARAEKKRAQEERKLAQEEEKLaqEERQLAQEERKlaqayvkitQDDREMAQAEgKFAQKEETLAQRGEKLSQ 1653
Cdd:TIGR02794   52 ANRIQQQKKPAAKKEQERQKKLEQQAEEA--EKQRAAEQARQ---------KELEQRAAAE-KAAKQAEQAAKQAEEKQK 119

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 597709775  1654 EAEKLAQKRKKLAKKWEKVARE---EEKLAKKGG--KLAEVKNILAQKVEELPQR 1703
Cdd:TIGR02794  120 QAEEAKAKQAAEAKAKAEAEAErkaKEEAAKQAEeeAKAKAAAEAKKKAEEAKKK 174

PRK12704

phosphodiesterase; Provisional

1802-1988

1.85e-05

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.16 E-value: 1.85e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1802 REQLIEKKMKLAQKRerwinsmeeltkNKMILYQKKNLAQEKKnlaqeKEKLAQRKENLLYNKERLthsKKQLVQVKNKL 1881
Cdd:PRK12704   25 RKKIAEAKIKEAEEE------------AKRILEEAKKEAEAIK-----KEALLEAKEEIHKLRNEF---EKELRERRNEL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1882 gmfnkilAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLaqEKMKLALEKAMVQGKKRLrgeLDIA---K 1958
Cdd:PRK12704   85 -------QKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQEL--EKKEEELEELIEEQLQEL---ERISgltA 152

                         170       180       190
                  ....*....|....*....|....*....|...
gi 597709775 1959 EE-KALNLEM--KRLAEEKMRLVEGKETLSKGE 1988
Cdd:PRK12704  153 EEaKEILLEKveEEARHEAAVLIKEIEEEAKEE 185

WD40

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...

558-595

1.95e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.

Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 43.84 E-value: 1.95e-05

                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 597709775    558 KFIETLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWD 595
Cdd:smart00320    3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1396-1819

1.95e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.15 E-value: 1.95e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1396 FQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIE-RTPSWQDWKKAWDEWKQVHgET 1474
Cdd:COG4717    59 FKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELReELEKLEKLLQLLPLYQELE-AL 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1475 RKSWKAWKEEWE--KRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQqykdeeevtleeevsr 1552
Cdd:COG4717   138 EAELAELPERLEelEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL---------------- 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1553 egeekeQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQE-------------------- 1612
Cdd:COG4717   202 ------EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAaallallglggsllslilti 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1613 ------------------ERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKV-- 1672
Cdd:COG4717   276 agvlflvlgllallflllAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLre 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1673 AREEEKLAKKGGKLAEVKNILAQ-KVEELPQREQNLDWQEKELAQEleelewdmEELSWKEEELNQEEGKLVEEKKKLAE 1751
Cdd:COG4717   356 AEELEEELQLEELEQEIAALLAEaGVEDEEELRAALEQAEEYQELK--------EELEELEEQLEELLGELEELLEALDE 427

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775 1752 EEEALAWQRekLSEEETKLAQEEELLIQEKEKLAQHKEKMpEEEERLGRKREQLIEKKMKLAQKRERW 1819
Cdd:COG4717   428 EELEEELEE--LEEELEELEEELEELREELAELEAELEQL-EEDGELAELLQELEELKAELRELAEEW 492

COG5644

U3 small nucleolar RNA-associated protein 14 [Function unknown];

1761-2120

2.46e-05

U3 small nucleolar RNA-associated protein 14 [Function unknown];

Pssm-ID: 227931 [Multi-domain] Cd Length: 869 Bit Score: 50.09 E-value: 2.46e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1761 EKLSEEETKLAQEEELLIQEKEKlAQHKEKMPEEEERLGRKREqlIEKKMKLAQKRErwinsmeeltknkmilyqkkNLA 1840
Cdd:COG5644   369 EEVAERTRQLRFMRELMFREERK-AKRVAKIKSKTYRKIRKNR--KEKEMALIPKSE--------------------DLE 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1841 QEKKNLAQEKEKLAQR-KENLLYNK---ERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEkkl 1916
Cdd:COG5644   426 NEKSEEARALERMTQRhKNTSSWTRkmlERASHGEGTREAVNEQIRKGDELMQRIHGKEIMDGEDVSEFSDSDYDTN--- 502

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1917 vqvedslakKQEKLAQEKMKLALEKAMVQGKKRLRgeldiakEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSR-- 1994
Cdd:COG5644   503 ---------EQVSTAFEKIRNEEELKGVLGMKFMR-------DASNRQMAASKISVADLVKVENGDDIDVGELDEVGGda 566

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1995 ------QRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRE---S 2065
Cdd:COG5644   567 iyanagRREVFPVVEQRRKLAPRKRKEDFVTPSTSLEKSMDRILHGQKKRAEGAVVFEKPLEATENFNPWLDRKMRrikR 646

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775 2066 LSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIE---QSKLDI 2120
Cdd:COG5644   647 IKKKAYRRIRRDKRLKKKMPEEENTQENHLGSEKKRHGGVPDILLKEIEvedDEKTPI 704

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

1419-1832

3.81e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.35 E-value: 3.81e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1419 EMTKEERDMSEEVEEMATLE-EKVVKQEGK-------------LVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAwKEE 1484
Cdd:pfam17380  234 EKMERRKESFNLAEDVTTMTpEYTVRYNGQtmteneflnqllhIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKA-REV 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1485 WEKRLLQEEEKLHQAG-----------EKLSPE-----EEMLQEDKKLKWEEWKQVWENMLSSKSKEQQykdeeevtlee 1548
Cdd:pfam17380  313 ERRRKLEEAEKARQAEmdrqaaiyaeqERMAMErerelERIRQEERKRELERIRQEEIAMEISRMRELE----------- 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1549 evsrEGEEKEQQVTEEQRH-IQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKlaqayvkitqdd 1627
Cdd:pfam17380  382 ----RLQMERQQKNERVRQeLEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA------------ 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1628 REMAQAEgkfaQKEETLAQRGEKLSQEAEKlaQKRKKLAKKWEKvarEEEKLAKKggklaEVKNILAQKVEElpqREQNL 1707
Cdd:pfam17380  446 REMERVR----LEEQERQQQVERLRQQEEE--RKRKKLELEKEK---RDRKRAEE-----QRRKILEKELEE---RKQAM 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1708 DWQEKELAQELEelewDMEElswKEEELNQEEgklveekkklaeeeealawqREKLSEEETKLAQEeellIQEKEKLAQH 1787
Cdd:pfam17380  509 IEEERKRKLLEK----EMEE---RQKAIYEEE--------------------RRREAEEERRKQQE----MEERRRIQEQ 557

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 597709775  1788 KEKMPEEEERL-GRKREQLIEKKMKLAQKRERWINSMEELTKNKMI 1832
Cdd:pfam17380  558 MRKATEERSRLeAMEREREMMRQIVESEKARAEYEATTPITTIKPI 603

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1559-1707

3.93e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 3.93e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1559 QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE------EKLAQEERQLAQEERKLAQAYVKITQDDREMAQ 1632
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQirgnggDRLEQLEREIERLERELEERERRRARLEALLAA 370

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 597709775 1633 AEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707
Cdd:COG4913   371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL 445

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1573-2004

5.33e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 5.33e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1573 KWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEgkFAQKEETLAQRGEKLS 1652
Cdd:COG4717    61 PQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--KLLQLLPLYQELEALE 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1653 QEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELP----QREQNLDWQEKELAQELEELEwdmEEL 1728
Cdd:COG4717   139 AELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlateEELQDLAEELEELQQRLAELE---EEL 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1729 SWKEEELNQEEGKLVEEKKKLAEEEealawQREKLSEEETKLAQEEELL----------------------------IQE 1780
Cdd:COG4717   216 EEAQEELEELEEELEQLENELEAAA-----LEERLKEARLLLLIAAALLallglggsllsliltiagvlflvlgllaLLF 290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1781 KEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWIN---SMEELTKNKMILYQKKNLAQEKKNLAQE--KEKLAQ 1855
Cdd:COG4717   291 LLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPpdlSPEELLELLDRIEELQELLREAEELEEElqLEELEQ 370

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1856 RKENLLY-----NKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETV-IKKKEKLAETEKKLVQVEDSLAKKQEK 1929
Cdd:COG4717   371 EIAALLAeagveDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLeALDEEELEEELEELEEELEELEEELEE 450

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 597709775 1930 LAQEKMKLALEKAMVQGKKRLRgelDIAKEEKALNLEMKRLAEEKMRLVEGKETLSkgETPETSRQRKMTQVEQE 2004
Cdd:COG4717   451 LREELAELEAELEQLEEDGELA---ELLQELEELKAELRELAEEWAALKLALELLE--EAREEYREERLPPVLER 520

PRK12704

phosphodiesterase; Provisional

2051-2166

5.90e-05

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 48.62 E-value: 5.90e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2051 KLAKASRKLIKKRESLSKEPAKLNKILKA---LQKLTRD-ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFS 2126
Cdd:PRK12704   34 KEAEEEAKRILEEAKKEAEAIKKEALLEAkeeIHKLRNEfEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELE 113

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 597709775 2127 EKRSELTKDEKKLARKQRKLANKMRRMINKEEK---MTEEESK 2166
Cdd:PRK12704  114 KKEKELEQKQQELEKKEEELEELIEEQLQELERisgLTAEEAK 156

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1558-1707

6.61e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 6.61e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1558 EQQVTEEQRHIQE-EHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Cdd:COG4942    61 ERRIAALARRIRAlEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQY 140

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 597709775 1637 FAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707
Cdd:COG4942   141 LKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAEL 211

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1840-2030

7.02e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 7.02e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1840 AQEKKNLAQEKEKLAQRKENLlynKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQV 1919
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAEL---EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1920 EDSLAKKQEKLA-----------QEKMKLALE-KAMVQGKKRLR--GEL--DIAKEEKALNLEMKRLAEEKMRLVEGKET 1983
Cdd:COG4942    96 RAELEAQKEELAellralyrlgrQPPLALLLSpEDFLDAVRRLQylKYLapARREQAEELRADLAELAALRAELEAERAE 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 597709775 1984 LSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESE 2030
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEA 222

PRK12704

phosphodiesterase; Provisional

1759-1855

1.07e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.85 E-value: 1.07e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEE---LTKN---KMI 1832
Cdd:PRK12704   80 RRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisgLTAEeakEIL 159

                          90       100
                  ....*....|....*....|....
gi 597709775 1833 LYQ-KKNLAQEKKNLAQEKEKLAQ 1855
Cdd:PRK12704  160 LEKvEEEARHEAAVLIKEIEEEAK 183

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1802-2268

1.08e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.01 E-value: 1.08e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1802 REQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKnLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKL 1881
Cdd:COG1196   219 KEELKELEAELLLLKLRELEAELEELEAELEELEAE-LEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1882 GMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQgkkrlrgelDIAKEEK 1961
Cdd:COG1196   298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA---------EAEEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1962 ALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRG 2041
Cdd:COG1196   369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2042 QRIfvqgQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDE-RKLTQEEIKMTKMKRALFVKERRLSIEQSKL-- 2118
Cdd:COG1196   449 EEE----AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAaRLLLLLEAEADYEGFLEGVKAALLLAGLRGLag 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2119 ---DIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMI-----NKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVI 2190
Cdd:COG1196   525 avaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIeylkaAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775 2191 PFLkRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEEREEEEE 2268
Cdd:COG1196   605 ASD-LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

1557-1702

1.15e-04

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 47.56 E-value: 1.15e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1557 KEQQVTEEQRhiQEEHKWARIhrKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKlaqayvkitqdDREMAQAEGK 1636
Cdd:COG2268   221 REAEEAELEQ--EREIETARI--AEAEAELAKKKAEERREAETARAEAEAAYEIAEANA-----------EREVQRQLEI 285

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1637 FAQKEETLAQRGEKLSQEAEKLAQKRKKL-AKKWEKVAREE---EKLAKKGGKLAEVKNILAQKVEELPQ 1702
Cdd:COG2268   286 AEREREIELQEKEAEREEAELEADVRKPAeAEKQAAEAEAEaeaEAIRAKGLAEAEGKRALAEAWNKLGD 355

Caldesmon

pfam02029

Caldesmon;

1598-2014

1.18e-04

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 47.55 E-value: 1.18e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1598 EEEKLAQEERQLAQEERKlaqayvkitqddremaqaegKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEE 1677
Cdd:pfam02029    3 DEEEAARERRRRAREERR--------------------RQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEE 62

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1678 KLAKKGGKLAEVKNilaQKVEELPQREQNLDWQEKElaqeleelewdmEELSWKEEELNQEEgklveekkklaeeEEALA 1757
Cdd:pfam02029   63 AFLDRTAKREERRQ---KRLQEALERQKEFDPTIAD------------EKESVAERKENNEE-------------EENSS 114

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1758 WQREKLSEEETKLAQEEELLIQEKEklaqHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMIlyQKK 1837
Cdd:pfam02029  115 WEKEEKRDSRLGRYKEEETEIREKE----YQENKWSTEVRQAEEEGEEEEDKSEEAEEVPTENFAKEEVKDEKIK--KEK 188

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1838 NLAQEKKNLAQEKEKLAQRKENllyNKERLTHSKKqlVQVKNKLGMFNkilaqveEKLTQEKETvikkkEKLAETEKKLV 1917
Cdd:pfam02029  189 KVKYESKVFLDQKRGHPEVKSQ---NGEEEVTKLK--VTTKRRQGGLS-------QSQEREEEA-----EVFLEAEQKLE 251

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1918 QVEDSLAKKQEklaqekmklalekamvQGKKRLRGEldiaKEEKALNL-EMKRLAEEKMRLVEgketlskgetpETSRQR 1996
Cdd:pfam02029  252 ELRRRRQEKES----------------EEFEKLRQK----QQEAELELeELKKKREERRKLLE-----------EEEQRR 300

                          410
                   ....*....|....*...
gi 597709775  1997 KmtqveQELFERKLSLEE 2014
Cdd:pfam02029  301 K-----QEEAERKLREEE 313

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1759-1971

1.31e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.07 E-value: 1.31e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1759 QREKLSEEETKLAQeeelLIQEKEKLAQHKEKMPEEEERLGRKREQLiEKKMKLAQKRERWINSMEELTKNKMILYQKKn 1838
Cdd:COG4942    18 QADAAAEAEAELEQ----LQQEIAELEKELAALKKEEKALLKQLAAL-ERRIAALARRIRALEQELAALEAELAELEKE- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1839 LAQEKKNLAQEKEKLAQR-----------KENLLYNKE-------RLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKE 1900
Cdd:COG4942    92 IAELRAELEAQKEELAELlralyrlgrqpPLALLLSPEdfldavrRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 597709775 1901 TVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELD--IAKEEKALNLEMKRLA 1971
Cdd:COG4942   172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEalIARLEAEAAAAAERTP 244

WD40

pfam00400

WD domain, G-beta repeat;

558-595

1.70e-04

WD domain, G-beta repeat;

Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 41.18 E-value: 1.70e-04

                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 597709775   558 KFIETLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWD 595
Cdd:pfam00400    2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39

TolA

COG3064

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

1557-1809

1.77e-04

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 46.96 E-value: 1.77e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1557 KEQQVTEEQRHIQEEhkwARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQlAQEERKLAQAyvkitqdDREMAQAEGK 1636
Cdd:COG3064    24 EKRAAAEAEQKAKEE---AEEERLAELEAKRQAEEEAREAKAEAEQRAAELA-AEAAKKLAEA-------EKAAAEAEKK 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1637 FAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQ 1716
Cdd:COG3064    93 AAAEKAKAAKEAEAAAAAEKAAAAAEKEKAEEAKRKAEEEAKRKAEEERKAAEAEAAAKAEAEAARAAAAAAAAAAAAAA 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1717 ELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796
Cdd:COG3064   173 RAAAGAAAALVAAAAAAVEAADTAAAAAAALAAAAAAAAADAALLALAVAARAAAASREAALAAVEATEEAALGGAEEAA 252

                         250
                  ....*....|...
gi 597709775 1797 RLGRKREQLIEKK 1809
Cdd:COG3064   253 DLAAVGVLGAALA 265

WD40

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...

233-272

1.98e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.

Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.76 E-value: 1.98e-04

                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 597709775    233 QGHPLHSFQAHQSGVICIRSRPEAHTLLTAGSDSLIKEWN 272
Cdd:smart00320    1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1649-2104

2.24e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 2.24e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1649 EKLSQEAEKLaqkRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLdwqekelaqeleelewdmEEL 1728
Cdd:COG4717    49 ERLEKEADEL---FKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL------------------EEL 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1729 SWKEEELNQEEGKLVEEKKKLAeeeealawQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEK 1808
Cdd:COG4717   108 EAELEELREELEKLEKLLQLLP--------LYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEEL 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1809 KMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKIL 1888
Cdd:COG4717   180 EELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALL 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1889 AQVEEKLTQEKETV------------------IKKKEKLAETEKKLvqvEDSLAKKQEKLAQEKMKLALEKAMVQG---K 1947
Cdd:COG4717   260 ALLGLGGSLLSLILtiagvlflvlgllallflLLAREKASLGKEAE---ELQALPALEELEEEELEELLAALGLPPdlsP 336

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1948 KRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKE-----TLSKGETPETSRQRkmtqveQELFERKLSLEEKILLHEDR 2022
Cdd:COG4717   337 EELLELLDRIEELQELLREAEELEEELQLEELEQEiaallAEAGVEDEEELRAA------LEQAEEYQELKEELEELEEQ 410

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2023 ILAMEESEIAkgKLEFTRGQRIFVQGQRkLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKR 2102
Cdd:COG4717   411 LEELLGELEE--LLEALDEEELEEELEE-LEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRE 487


                  ..
gi 597709775 2103 AL 2104
Cdd:COG4717   488 LA 489

PRK12704

phosphodiesterase; Provisional

2073-2174

2.30e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 2.30e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2073 LNKILKALQKLTRDERKLTQEEIKM---TKMKRALF-VKERrlsIEQSKLDIkEWDFSEKRSELTKDEKKLARKQRKLAN 2148
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRILEEAKKeaeAIKKEALLeAKEE---IHKLRNEF-EKELRERRNELQKLEKRLLQKEENLDR 100

                          90       100
                  ....*....|....*....|....*.
gi 597709775 2149 KMRRMINKEEKMTEEESKLARKHSEV 2174
Cdd:PRK12704  101 KLELLEKREEELEKKEKELEQKQQEL 126

HEC1

COG5185

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...

1793-2169

2.67e-04

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 46.49 E-value: 2.67e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1793 EEEERLGRKREQLIEKKMKLAQKRERwINSMEELTKNKMILYQKKNLAQEKKNLA-------------------QEKEKL 1853
Cdd:COG5185   147 ADIEASYGEVETGIIKDIFGKLTQEL-NQNLKKLEIFGLTLGLLKGISELKKAEPsgtvnsikesetgnlgsesTLLEKA 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1854 AQrKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEE--------------KLTQEKETVIKK----KEKLAETEKK 1915
Cdd:COG5185   226 KE-IINIEEALKGFQDPESELEDLAQTSDKLEKLVEQNTDlrleklgenaesskRLNENANNLIKQfentKEKIAEYTKS 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1916 LVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVegketlskGETPETSRQ 1995
Cdd:COG5185   305 IDIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIV--------GEVELSKSS 376

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1996 RKMTQVEQELFERKLSLEEK---ILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAK 2072
Cdd:COG5185   377 EELDSFKDTIESTKESLDEIpqnQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMRE 456

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2073 LNKILKALQKLTRDERKLTQEEIKMTKMkralfvkERRLSIEQSKLDIKEwdfsEKRSELTKDEKKLArKQRKLANKMRR 2152
Cdd:COG5185   457 ADEESQSRLEEAYDEINRSVRSKKEDLN-------EELTQIESRVSTLKA----TLEKLRAKLERQLE-GVRSKLDQVAE 524

                         410
                  ....*....|....*..
gi 597709775 2153 MINKEEKMTEEESKLAR 2169
Cdd:COG5185   525 SLKDFMRARGYAHILAL 541

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

1592-2055

2.72e-04

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.76 E-value: 2.72e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1592 ERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEK 1671
Cdd:pfam12128  603 RERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANE 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1672 VAREEEKLAKKGGKlaEVKNILAQKVEELpqREQNLDWQEKELAQeleelewdmeelswkEEELNQEEGKLVEekkklae 1751
Cdd:pfam12128  683 RLNSLEAQLKQLDK--KHQAWLEEQKEQK--REARTEKQAYWQVV---------------EGALDAQLALLKA------- 736

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1752 eeealawqrEKLSEEETKLAQEEELLIQEKEKLAQhkeKMPEEEERLGRKRE-QLIEKKMKLAQKRERWINSMEEltknk 1830
Cdd:pfam12128  737 ---------AIAARRSGAKAELKALETWYKRDLAS---LGVDPDVIAKLKREiRTLERKIERIAVRRQEVLRYFD----- 799

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1831 milYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHS-KKQLVQVKNKLGMFNKILAQVEEKLTQEKeTVIKKKEKL 1909
Cdd:pfam12128  800 ---WYQETWLQRRPRLATQLSNIERAISELQQQLARLIADtKLRRAKLEMERKASEKQQVRLSENLRGLR-CEMSKLATL 875

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1910 AEtEKKLVQVEDSLAkkqEKLAQ-EKMKLALEKAMVQGKKRLRGELDIAKEEKAlnlemKRLAEEKMRLVEGKETLSKGE 1988
Cdd:pfam12128  876 KE-DANSEQAQGSIG---ERLAQlEDLKLKRDYLSESVKKYVEHFKNVIADHSG-----SGLAETWESLREEDHYQNDKG 946

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 597709775  1989 TpETSRQRKMTQVEQELFErkLSLEEKILLHED--RILAMEESEIAKGKLEFtrGQRIFVQGqRKLAKA 2055
Cdd:pfam12128  947 I-RLLDYRKLVPYLEQWFD--VRVPQSIMVLREqvSILGVDLTEFYDVLADF--DRRIASFS-RELQRE 1009

PRK12704

phosphodiesterase; Provisional

1741-1913

2.77e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.31 E-value: 2.77e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1741 KLVEEKKKLAEEeealawQREKLSEEETKLAQE--EELLIQEKEKLAQHKEKMpeeEERLGRKREQLIEKKMKLAQKRER 1818
Cdd:PRK12704   27 KIAEAKIKEAEE------EAKRILEEAKKEAEAikKEALLEAKEEIHKLRNEF---EKELRERRNELQKLEKRLLQKEEN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1819 WINSMEELTKnkmilyQKKNLAQEKKNLAQEKEKLAQRKENLlynKERLTHSKKQLVQVKNkLGMF---NKILAQVEEKL 1895
Cdd:PRK12704   98 LDRKLELLEK------REEELEKKEKELEQKQQELEKKEEEL---EELIEEQLQELERISG-LTAEeakEILLEKVEEEA 167

                         170
                  ....*....|....*...
gi 597709775 1896 TQEKETVIKKKEKLAETE 1913
Cdd:PRK12704  168 RHEAAVLIKEIEEEAKEE 185

Surf_Exclu_PgrA

TIGR04320

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...

1832-1931

2.90e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.

Pssm-ID: 275124 [Multi-domain] Cd Length: 356 Bit Score: 45.87 E-value: 2.90e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1832 ILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQV--------EEKLTQEKETVI 1903
Cdd:TIGR04320  249 IPNPPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAqaqalqtaQNNLATAQAALA 328

                           90       100
                   ....*....|....*....|....*...
gi 597709775  1904 KKKEKLAETEKKLVQVEDSLAKKQEKLA 1931
Cdd:TIGR04320  329 NAEARLAKAKEALANLNADLAKKQAALD 356

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1437-1942

3.07e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.30 E-value: 3.07e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1437 LEEKVVKQEGKLVmierTPSWQDWKKAWDEWKQVHgETRKSWKAWKEEWEkRLLQEEEKLHQAGEKLSPEEEMLQEDKKl 1516
Cdd:COG4717    47 LLERLEKEADELF----KPQGRKPELNLKELKELE-EELKEAEEKEEEYA-ELQEELEELEEELEELEAELEELREELE- 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1517 KWEEWKQVWENMLSSKSKEQQYKDEEE--------VTLEEEVSREGEEKEQQVTEEQRHIQEEhkwARIHRKRARAEKKR 1588
Cdd:COG4717   120 KLEKLLQLLPLYQELEALEAELAELPErleeleerLEELRELEEELEELEAELAELQEELEEL---LEQLSLATEEELQD 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEklaqkrkklakk 1668
Cdd:COG4717   197 LAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGL------------ 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1669 wekVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKK 1748
Cdd:COG4717   265 ---GGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLE 341

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1749 LAEEEEALAWQREKLSEEETKLaQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERwINSMEELTK 1828
Cdd:COG4717   342 LLDRIEELQELLREAEELEEEL-QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQ-LEELLGELE 419

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1829 NKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQvKNKLgmfnkilaqveEKLTQEKETVIKKKEK 1908
Cdd:COG4717   420 ELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE-DGEL-----------AELLQELEELKAELRE 487

                         490       500       510
                  ....*....|....*....|....*....|....
gi 597709775 1909 LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKA 1942
Cdd:COG4717   488 LAEEWAALKLALELLEEAREEYREERLPPVLERA 521

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1562-1882

3.29e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.48 E-value: 3.29e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1562 TEEQRHIQEEhkwARIHRKRARAEKKRAQEERK-----LAQEEEKL-AQEERQLA--QEERKLAQAYVKITQDDREMAQA 1633
Cdd:COG3096   363 LEEQEEVVEE---AAEQLAEAEARLEAAEEEVDslksqLADYQQALdVQQTRAIQyqQAVQALEKARALCGLPDLTPENA 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1634 EGKFAQKEETLAQRGEKLSQEAEKLA-------QKRKKL------------AKKWEKvAREEEKLAKKGGKLAEVKNILA 1694
Cdd:COG3096   440 EDYLAAFRAKEQQATEEVLELEQKLSvadaarrQFEKAYelvckiageverSQAWQT-ARELLRRYRSQQALAQRLQQLR 518

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1695 QKVEELPQREQNLDwqekelaqeleelewDMEELSwkeEELNQEEGKlveekkklaeeeealawQREKLSEEETKLAQEE 1774
Cdd:COG3096   519 AQLAELEQRLRQQQ---------------NAERLL---EEFCQRIGQ-----------------QLDAAEELEELLAELE 563

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1775 ELLiqekEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWI-----------NSMEELTKNKMILYQKKNLAQEK 1843
Cdd:COG3096   564 AQL----EELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLaaqdalerlreQSGEALADSQEVTAAMQQLLERE 639

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 597709775 1844 KNLAQEKEKLAQRKENLLYNKERLTHS----KKQLVQVKNKLG 1882
Cdd:COG3096   640 REATVERDELAARKQALESQIERLSQPggaeDPRLLALAERLG 682

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

1786-2158

3.29e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 45.66 E-value: 3.29e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1786 QHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTK-----NKMILYQKKNLAQEKKNLAQEKEKLAQRKENL 1860
Cdd:COG4372     3 RLGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEeleqlREELEQAREELEQLEEELEQARSELEQLEEEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1861 LYNKERLTHSKKQLVQVKNKLGMFNKILAQVE---EKLTQEKETVIKKKEKLAETEKKLVQvedSLAKKQEKLAQEKMKL 1937
Cdd:COG4372    83 EELNEQLQAAQAELAQAQEELESLQEEAEELQeelEELQKERQDLEQQRKQLEAQIAELQS---EIAEREEELKELEEQL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1938 ALEKAMVQGKKRLRGELDIAKEEKALNlemkRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFerklslEEKIL 2017
Cdd:COG4372   160 ESLQEELAALEQELQALSEAEAEQALD----ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAK------DSLEA 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2018 LHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKM 2097
Cdd:COG4372   230 KLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSL 309

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 597709775 2098 TKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEE 2158
Cdd:COG4372   310 IGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVADG 370

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

1760-2157

3.73e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.48 E-value: 3.73e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1760 REKLSEEETKLAQEEELLIQEKEKLAQHKEK-------MPE----EEERLGRKREQLiEKKMKLAQKRERWI----NSME 1824
Cdd:COG3096   842 RQRRSELERELAQHRAQEQQLRQQLDQLKEQlqllnklLPQanllADETLADRLEEL-REELDAAQEAQAFIqqhgKALA 920

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1825 ELTKNKMIL----YQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHskkqlvqvknklgmFNkiLAQVEEKLTQEKE 1900
Cdd:COG3096   921 QLEPLVAVLqsdpEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPH--------------FS--YEDAVGLLGENSD 984

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1901 TVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELdiAKEEKALNL----EMKRLAEEKMR 1976
Cdd:COG3096   985 LNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQEL--EQELEELGVqadaEAEERARIRRD 1062

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1977 LVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKillheDRILAMEESEIAKgklefTRGQRIfvqgqRKLAKAS 2056
Cdd:COG3096  1063 ELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAER-----DYKQEREQVVQAK-----AGWCAV-----LRLARDN 1127

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2057 ---RKLiKKRESLSKEPAKLNKIL-KALQKL---------TRDERKLTqEEIKMTKMKRALFV------KER-------- 2109
Cdd:COG3096  1128 dveRRL-HRRELAYLSADELRSMSdKALGALrlavadnehLRDALRLS-EDPRRPERKVQFYIavyqhlRERirqdiirt 1205

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775 2110 --------RLSIEQSKLDikewdfsekrSELTKDEKKLARKQRKLANKMRRMINKE 2157
Cdd:COG3096  1206 ddpveaieQMEIELARLT----------EELTSREQKLAISSESVANIIRKTIQRE 1251

GBP_C

pfam02841

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...

1758-1858

3.94e-04

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.

Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 45.36 E-value: 3.94e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1758 WQREKLSEEETKLAQEEELLIQEKEKLAQHkekmpEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNkmiLYQKk 1837
Cdd:pfam02841  181 FLQSKEAVEEAILQTDQALTAKEKAIEAER-----AKAEAAEAEQELLREKQKEEEQMMEAQERSYQEHVKQ---LIEK- 251

                           90       100
                   ....*....|....*....|.
gi 597709775  1838 nLAQEKKNLAQEKEKLAQRKE 1858
Cdd:pfam02841  252 -MEAEREQLLAEQERMLEHKL 271

ClpA

COG0542

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...

1888-2020

3.98e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 46.23 E-value: 3.98e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1888 LAQVEEKLTQ-EKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDiAKEEKALNLE 1966
Cdd:COG0542   413 LDELERRLEQlEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELE-QRYGKIPELE 491

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 597709775 1967 mKRLAEEKMRLVEgKETLSKGE-TPET-----SRQ-----RKMTQVEQelfERKLSLEEKilLHE 2020
Cdd:COG0542   492 -KELAELEEELAE-LAPLLREEvTEEDiaevvSRWtgipvGKLLEGER---EKLLNLEEE--LHE 549

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1761-2232

4.08e-04

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 46.32 E-value: 4.08e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1761 EKLSEEETKLAQEEE---LLIQEKEKLAQHKEKMPE--EEERLGRKREQL----IEKKMKlaqKRERWINSMEEltknkm 1831
Cdd:pfam01576   75 EILHELESRLEEEEErsqQLQNEKKKMQQHIQDLEEqlDEEEAARQKLQLekvtTEAKIK---KLEEDILLLED------ 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1832 ilyQKKNLAQEKKNLaqeKEKLAQRKENLLYNKERLthskKQLVQVKNKLGMFNKILA---QVEEKLTQEKETVIKK--- 1905
Cdd:pfam01576  146 ---QNSKLSKERKLL---EERISEFTSNLAEEEEKA----KSLSKLKNKHEAMISDLEerlKKEEKGRQELEKAKRKleg 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1906 -----KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKL---ALEKAMVQGKKR-LRGELDIAKEEKALNLEMKRLAEEKMR 1976
Cdd:pfam01576  216 estdlQEQIAELQAQIAELRAQLAKKEEELQAALARLeeeTAQKNNALKKIReLEAQISELQEDLESERAARNKAEKQRR 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1977 -LVEGKETLsKGETPET-----SRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEEseiakgkleftRGQRIFVQGQR 2050
Cdd:pfam01576  296 dLGEELEAL-KTELEDTldttaAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQ-----------KHTQALEELTE 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2051 KLAKASR---KLIKKRESLSKEPAKLNKILKALQkltrdERKLTQEEikmtkmkralfvKERRLSIEQSKLDIKEWDFSE 2127
Cdd:pfam01576  364 QLEQAKRnkaNLEKAKQALESENAELQAELRTLQ-----QAKQDSEH------------KRKKLEGQLQELQARLSESER 426

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2128 KRSELtkdEKKLARKQRKLANkMRRMINkeekmtEEESKLARKHSEVilddeeeggieeEEVIPFLKRRWRKRKEAKRgd 2207
Cdd:pfam01576  427 QRAEL---AEKLSKLQSELES-VSSLLN------EAEGKNIKLSKDV------------SSLESQLQDTQELLQEETR-- 482

                          490       500       510
                   ....*....|....*....|....*....|
gi 597709775  2208 kPKEKFSSQVDEVESE-----EHFSEEMES 2232
Cdd:pfam01576  483 -QKLNLSTRLRQLEDErnslqEQLEEEEEA 511

sbcc

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

1759-2250

7.38e-04

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.34 E-value: 7.38e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLgrkreQLIEkkMKLAQKRERWINSMEELTKnkmilyQKKN 1838
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRS-----QLLT--LCTPCMPDTYHERKQVLEK------ELKH 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1839 LAQEKKNLAQEKEKLAQRKENLlynkERLTHSKKQLVQVKNKLGMFNKILAQVEEklTQEKETVIKKKEKLAETEKKLVQ 1918
Cdd:TIGR00618  231 LREALQQTQQSHAYLTQKREAQ----EEQLKKQQLLKQLRARIEELRAQEAVLEE--TQERINRARKAAPLAAHIKAVTQ 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1919 VEDSLAKKQEKLaQEKMKLaLEKAMVQGKKRLRGELDIAKEEKALNLEMKrlAEEKMRLVEGKETLSKGETPE--TSRQR 1996
Cdd:TIGR00618  305 IEQQAQRIHTEL-QSKMRS-RAKLLMKRAAHVKQQSSIEEQRRLLQTLHS--QEIHIRDAHEVATSIREISCQqhTLTQH 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1997 KMTQVEQ-ELFERKLSLEEKILLHEDRILAMEESEIAKGKLEftRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNK 2075
Cdd:TIGR00618  381 IHTLQQQkTTLTQKLQSLCKELDILQREQATIDTRTSAFRDL--QGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2076 IL--KALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQskldikewdfsEKRSELTKDEKKLARKQRKLAN----- 2148
Cdd:TIGR00618  459 IHlqESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQ-----------EEPCPLCGSCIHPNPARQDIDNpgplt 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2149 -KMRRMINKEEKMTEEESKLarkhsEVILDDEeeggieeeevipfLKRRWRKRKEAKRGDKPKEKFSSQVDEVeseehfS 2227
Cdd:TIGR00618  528 rRMQRGEQTYAQLETSEEDV-----YHQLTSE-------------RKQRASLKEQMQEIQQSFSILTQCDNRS------K 583

                          490       500
                   ....*....|....*....|...
gi 597709775  2228 EEMESLLDELEKQESLSSEEEEE 2250
Cdd:TIGR00618  584 EDIPNLQNITVRLQDLTEKLSEA 606

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1558-1688

7.62e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 7.62e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1558 EQQVTEEQRHIQE-EHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLA--------QAYVK-ITQDD 1627
Cdd:COG1579    23 EHRLKELPAELAElEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvrnnkeyEALQKeIESLK 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775 1628 REMAQAE-------GKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAE 1688
Cdd:COG1579   103 RRISDLEdeilelmERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAA 170

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

1559-1673

7.90e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.44 E-value: 7.90e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1559 QQVTEEQRHIQEEHKWAR--IHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Cdd:COG3883   125 SKIADADADLLEELKADKaeLEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAE 204

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 597709775 1637 FAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVA 1673
Cdd:COG3883   205 LAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 241

mukB

PRK04863

chromosome partition protein MukB;

1557-1882

8.28e-04

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 45.33 E-value: 8.28e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1557 KEQQVTEEQRHIQEEHKWARIHRKRARA-----EK-KRAQEErkLAQEEEKL--AQEERQLAQEERKLAQAYVKITQDDR 1628
Cdd:PRK04863  315 ELAELNEAESDLEQDYQAASDHLNLVQTalrqqEKiERYQAD--LEELEERLeeQNEVVEEADEQQEENEARAEAAEEEV 392

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1629 EMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKL----------AKKW--EKVAREEE---KLAKKGGKLAEVKNIL 1693
Cdd:PRK04863  393 DELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLcglpdltadnAEDWleEFQAKEQEateELLSLEQKLSVAQAAH 472

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1694 AQ--KVEELPQR-----EQNLDWQEKELAQEleelewDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQRE---KL 1763
Cdd:PRK04863  473 SQfeQAYQLVRKiagevSRSEAWDVARELLR------RLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEfckRL 546

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1764 SEEETKLAQEEELLIQEKEKLAQHKEKMPEEEER---LGRKREQLIEKKMKLAQKRERWIN-----------SMEELTKN 1829
Cdd:PRK04863  547 GKNLDDEDELEQLQEELEARLESLSESVSEARERrmaLRQQLEQLQARIQRLAARAPAWLAaqdalarlreqSGEEFEDS 626

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 597709775 1830 KMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTH----SKKQLVQVKNKLG 1882
Cdd:PRK04863  627 QDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSQpggsEDPRLNALAERFG 683

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1557-1680

8.75e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 8.75e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1557 KEQQVTEEQRHIQEehkwARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLA---QAYVKITQDDREMAQA 1633
Cdd:COG4913   615 LEAELAELEEELAE----AEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAeleAELERLDASSDDLAAL 690

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 597709775 1634 EgkfaQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLA 1680
Cdd:COG4913   691 E----EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

YscO-like

pfam16789

YscO-like protein; This family of proteins is similar to the type III secretion protein YscO. ...

1837-1960

8.95e-04

YscO-like protein; This family of proteins is similar to the type III secretion protein YscO. The family includes Chlamydia trachomatis CT670 which is found in a type III secretion gene cluster. CT670 interacts with CT671, a putative YscP homolog and CT670 and CT671 may form a chaperone-effector pair.

Pssm-ID: 435583 [Multi-domain] Cd Length: 160 Bit Score: 42.52 E-value: 8.95e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1837 KNLAQEKKNLAQEKEKLAQRKENLlynKERLTHSKKQLVQVK---------NKLGMFNKILAQVEEKLTQEKETVIKKKE 1907
Cdd:pfam16789   21 KVVKDKKRALEKEKEKLAELEAER---DKVRKHKKAKMQQLRdemdrgttsDKILQMKRYIKVVKERLKQEEKKVQDQKE 97

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 597709775  1908 KLAETEKKLVQVEDSLAKKQEKLaqEKMKLALEKAMVQGKKRLRGELDIAKEE 1960
Cdd:pfam16789   98 QVRTAARNLEIAREELKKKRQEV--EKLEKHKKEWVKEMKKEEEDQEEREQDE 148

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1836-1973

9.05e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.37 E-value: 9.05e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1836 KKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNklgmfNKILaqveEKLTQEKETVikkKEKLAETEKK 1915
Cdd:COG1579    44 EARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-----NKEY----EALQKEIESL---KRRISDLEDE 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1916 LVQVEDSLAKKQEKLAQEKMKLA-LEKAMVQGKKRLRGEL-DIAKEEKALNLEMKRLAEE 1973
Cdd:COG1579   112 ILELMERIEELEEELAELEAELAeLEAELEEKKAELDEELaELEAELEELEAEREELAAK 171

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1760-2174

9.73e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 9.73e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1760 REKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLA---QKRERWINSMEELTKNKMILYQK 1836
Cdd:COG4717    52 EKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEeleAELEELREELEKLEKLLQLLPLY 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1837 KNLAQEKKNLAQEKEKLA---QRKENLLYNKERLTHSKKQLVQVKNKLGM-FNKILAQVEEKLTQEKETVIKKKEKLAET 1912
Cdd:COG4717   132 QELEALEAELAELPERLEeleERLEELRELEEELEELEAELAELQEELEElLEQLSLATEEELQDLAEELEELQQRLAEL 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1913 EKKLVQVEDSLAKKQEKLAQEKMKLALEkAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMR------LVEGKETLSK 1986
Cdd:COG4717   212 EEELEEAQEELEELEEELEQLENELEAA-ALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiagvlfLVLGLLALLF 290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1987 GETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKL-----IK 2061
Cdd:COG4717   291 LLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqleelEQ 370

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 2062 KRESL-----SKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEwdFSEKRSELTKDE 2136
Cdd:COG4717   371 EIAALlaeagVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEE--LEEELEELEEEL 448

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 597709775 2137 KKLARKQRKLANKMRRMINK---EEKMTEEESKLARKHSEV 2174
Cdd:COG4717   449 EELREELAELEAELEQLEEDgelAELLQELEELKAELRELA 489

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

1726-1954

9.87e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 9.87e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1726 EELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL 1805
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1806 IEKkMKLAQKRER------WINSMEELTKNKMILYQKKnLAQEKKNLAqekEKLAQRKENLLYNKERLTHSKKQLVQVKN 1879
Cdd:COG4942   107 AEL-LRALYRLGRqpplalLLSPEDFLDAVRRLQYLKY-LAPARREQA---EELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 597709775 1880 KLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLAlEKAMVQGKKRLRGEL 1954
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA-ERTPAAGFAALKGKL 255

PRK00106

ribonuclease Y;

1560-1697

1.01e-03

ribonuclease Y;

Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 44.47 E-value: 1.01e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1560 QVTEEQRHIQEEHKW-ARIHRKRARAEKKraQEERKLAQEEEKLAQEERQ-LAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Cdd:PRK00106   50 KAERDAEHIKKTAKReSKALKKELLLEAK--EEARKYREEIEQEFKSERQeLKQIESRLTERATSLDRKDENLSSKEKTL 127

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAkKGGKLAEVKNILAQKV 1697
Cdd:PRK00106  128 ESKEQSLTDKSKHIDEREEQVEKLEEQKKAELERVAALSQAEA-REIILAETENKLTHEI 186

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

562-635

1.09e-03

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 43.86 E-value: 1.09e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 597709775  562 TLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWDFHGrliGILDSSL--HFGPVCFandrgdlLVTFNQSLYLVSC 635
Cdd:cd00200     4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLET---GELLRTLkgHTGPVRD-------VAASADGTYLASG 69

tolA

cell envelope integrity inner membrane protein TolA; Provisional

1778-1962

1.19e-03

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 44.03 E-value: 1.19e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1778 IQEKEKLAQHKEKMPEEEERlgRKREQLIEKKMKLAQKrerwinsMEELTKNKMILYQKKNLAQEKKNLAQEKEKLA--Q 1855
Cdd:PRK09510   67 QQQQQKSAKRAEEQRKKKEQ--QQAEELQQKQAAEQER-------LKQLEKERLAAQEQKKQAEEAAKQAALKQKQAeeA 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1856 RKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIK-------------KKEKLAETEKKLVQVEDS 1922
Cdd:PRK09510  138 AAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKaeaeaaakaaaeaKKKAEAEAKKKAAAEAKK 217

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 597709775 1923 LAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKA 1962
Cdd:PRK09510  218 KAAAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAA 257

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

1760-2027

1.21e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 43.75 E-value: 1.21e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1760 REKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNL 1839
Cdd:pfam13868   79 EEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERIL 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1840 AQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKEtviKKKEKlAETEKKLVQV 1919
Cdd:pfam13868  159 EYLKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKE---RQKER-EEAEKKARQR 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1920 EDSLAKKQEKLAQEKMKLALEKAmvqgKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKgeTPETSRQRKMT 1999
Cdd:pfam13868  235 QELQQAREEQIELKERRLAEEAE----REEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEK--QIEEREEQRAA 308

                          250       260
                   ....*....|....*....|....*...
gi 597709775  2000 QVEQELFERKlsLEEKILLHEDRILAME 2027
Cdd:pfam13868  309 EREEELEEGE--RLREEEAERRERIEEE 334

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

1771-1962

1.26e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.05 E-value: 1.26e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1771 AQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERwinsMEELtknkmilyqKKNLAQEKKNLAQEK 1850
Cdd:COG3883    12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE----LEAL---------QAEIDKLQAEIAEAE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1851 EKLAQRKENLlynKERLTHSKKQ---------LVQVKN------KLGMFNKI----------LAQVEEKLTQEKETVIKK 1905
Cdd:COG3883    79 AEIEERREEL---GERARALYRSggsvsyldvLLGSESfsdfldRLSALSKIadadadlleeLKADKAELEAKKAELEAK 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 597709775 1906 KEKL----AETEKKLVQVEDSLAKKQEKLAQekmkLALEKAMVQGKKRLRGELDIAKEEKA 1962
Cdd:COG3883   156 LAELealkAELEAAKAELEAQQAEQEALLAQ----LSAEEAAAEAQLAELEAELAAAEAAA 212

PRK05035

electron transport complex protein RnfC; Provisional

1574-1677

1.29e-03

electron transport complex protein RnfC; Provisional

Pssm-ID: 235334 [Multi-domain] Cd Length: 695 Bit Score: 44.17 E-value: 1.29e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1574 WARIhRKRARAEKKRAQ-EERKLAQEEEKLAQEERQLAQEERKLAQAyvkitQDDRE--MAQAEGKFAQKEETLAQRGEK 1650
Cdd:PRK05035  439 RAIE-QEKKKAEEAKARfEARQARLEREKAAREARHKKAAEARAAKD-----KDAVAaaLARVKAKKAAATQPIVIKAGA 512

                          90       100
                  ....*....|....*....|....*..
gi 597709775 1651 LSQEAEKLAQKRKKLAKKWEKVAREEE 1677
Cdd:PRK05035  513 RPDNSAVIAAREARKAQARARQAEKQA 539

COG1340

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

1759-2015

1.32e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 43.36 E-value: 1.32e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1759 QREKLSEEETKLAQEEELLIqekEKLAQHKEKMPEEEErlgrKREQLIEKKMKLAQKRERWINSMEELTKnkmILYQKKN 1838
Cdd:COG1340    30 KRDELNEELKELAEKRDELN---AQVKELREEAQELRE----KRDELNEKVKELKEERDELNEKLNELRE---ELDELRK 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1839 LAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQlvqvKNKLgmFNKIlAQVEEKLtQEKETVIKKKEKLAETEKKLvq 1918
Cdd:COG1340   100 ELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEE----EKEL--VEKI-KELEKEL-EKAKKALEKNEKLKELRAEL-- 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1919 veDSLAKKQEKLAQEKMKLA-----LEKAMVQGKKR---LRGELDIAKEE-----KALNLEMKRLAEEKMRLVEGKETLS 1985
Cdd:COG1340   170 --KELRKEAEEIHKKIKELAeeaqeLHEEMIELYKEadeLRKEADELHKEiveaqEKADELHEEIIELQKELRELRKELK 247

                         250       260       270
                  ....*....|....*....|....*....|
gi 597709775 1986 KGEtpETSRQRKMTQVEQELFERKLSLEEK 2015
Cdd:COG1340   248 KLR--KKQRALKREKEKEELEEKAEEIFEK 275

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

1560-1700

1.38e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 44.09 E-value: 1.38e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1560 QVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQ-----DDREMAQAE 1634
Cdd:COG2268   238 RIAEAEAELAKKKAEERREAETARAEAEAAYEIAEANAEREVQRQLEIAEREREIELQEKEAEREEaeleaDVRKPAEAE 317

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775 1635 GKFAQKEEtlAQRGEKLSQEAEKLAQKRKKLAKKWEKVARE--EEKLAKkggKLAEVKNILAQKVEEL 1700
Cdd:COG2268   318 KQAAEAEA--EAEAEAIRAKGLAEAEGKRALAEAWNKLGDAaiLLMLIE---KLPEIAEAAAKPLEKI 380

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1585-1708

1.42e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.99 E-value: 1.42e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQ----------- 1653
Cdd:COG1579    16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnkeyealq 95

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1654 -EAEKLAQKRKKLAKK----WEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD 1708
Cdd:COG1579    96 kEIESLKRRISDLEDEilelMERIEELEEELAELEAELAELEAELEEKKAELDEELAELE 155

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

1423-1617

1.48e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 1.48e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1423 EERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHgETRKSWKAWKEEWEKRLLQEEEKLHQAGEK 1502
Cdd:COG4717   302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ-ELLREAEELEEELQLEELEQEIAALLAEAG 380

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1503 LSPEEEMLQEDKKL-KWEEWKQVWENMlssKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKR 1581
Cdd:COG4717   381 VEDEEELRAALEQAeEYQELKEELEEL---EEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAE 457

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 597709775 1582 ARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLA 1617
Cdd:COG4717   458 LEAELEQLEEDGELAELLQELEELKAELRELAEEWA 493

Nop53

pfam07767

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ...

1483-1630

1.50e-03

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ribosomal biogenesis. They are specifically involved in the processing beyond the 27S stage of 25S rRNA maturation. This family contains sequences that bear similarity to the glioma tumour suppressor candidate region gene 2 protein (p60). This protein has been found to interact with herpes simplex type 1 regulatory proteins.

Pssm-ID: 462259 [Multi-domain] Cd Length: 353 Bit Score: 43.44 E-value: 1.50e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1483 EEWEKRLLQEeeklHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMlsskskeqqykdeeevtleeevsregeekEQQVT 1562
Cdd:pfam07767  195 EDHQELLQKA----VEAEKKRLKEEEKLERVLEKIAESAATAEARE-----------------------------EKRKT 241

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775  1563 EEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREM 1630
Cdd:pfam07767  242 KAQRNKEKRRKEEEREAKEEKALKKKLAQLERLKEIAKEIAEKEKEREEKAEARKREKRKKKKEEKKL 309

MAP7

pfam05672

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...

1558-1678

1.54e-03

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.

Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 41.56 E-value: 1.54e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1558 EQQVTEEQRHIQ--EEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQayvkitQDDREMAQAEG 1635
Cdd:pfam05672   25 EQREREEQERLEkeEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRKAEEEAEE------REQREQEEQER 98

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 597709775  1636 KFAQKEETLAqrgeKLSQEAEKLAQKRKKLAKKWEKvAREEEK 1678
Cdd:pfam05672   99 LQKQKEEAEA----KAREEAERQRQEREKIMQQEEQ-ERLERK 136

PHA02529

capsid-scaffolding protein; Provisional

1582-1705

1.62e-03

capsid-scaffolding protein; Provisional

Pssm-ID: 222855 Cd Length: 278 Bit Score: 43.20 E-value: 1.62e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1582 ARAEKKRAQEERKLAQE----EEKLAQEERQLAQEERKLAQAYVKI---TQDDREMAQAegKFAQKEETLAQRGEKLSQE 1654
Cdd:PHA02529  136 SAKAKHNPLARRKQNPEnlfsVACEAKEEFEPEAELAALFEKVKKLfsrKKEDDAMTDE--QFADVHEAVEGVAEKIDHT 213

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 597709775 1655 AEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQ 1705
Cdd:PHA02529  214 SAQVATTETAEPPQEGKDTEENGETAEQFSALKETLDKLASKFNEEVPAPQ 264

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

1557-1700

1.70e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 43.71 E-value: 1.70e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1557 KEQQVtEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAyvkitqddreMAQAEGK 1636
Cdd:COG2268   275 AEREV-QRQLEIAEREREIELQEKEAEREEAELEADVRKPAEAEKQAAEAEAEAEAEAIRAKG----------LAEAEGK 343

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 597709775 1637 fAQKEETLAQRGEKLSQE--AEKLAQKRKKLAKKWEKV--AREEEKLAKKGGKLAEVKNILAQKVEEL 1700
Cdd:COG2268   344 -RALAEAWNKLGDAAILLmlIEKLPEIAEAAAKPLEKIdkITIIDGGNGGNGAGSAVAEALAPLLESL 410

CCDC34

pfam13904

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...

1476-1612

1.78e-03

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.

Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 42.38 E-value: 1.78e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1476 KSWKAWKEEWEKRLLQEEEKLHQAGEKlspEEEMLQEDKKLKWEEWKQvwenmlssKSKEQQYKDEEEVTLEEEVS---R 1552
Cdd:pfam13904   58 ENWLAAKQRQRQKELQAQKEEREKEEQ---EAELRKRLAKEKYQEWLQ--------RKARQQTKKREESHKQKAAEsasK 126

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 597709775  1553 EGEEKEQQVTEE--QRHIQEehkWARIHRKRARAEKKRAQEERKLAQEEEklaQEERQLAQE 1612
Cdd:pfam13904  127 SLAKPERKVSQEeaKEVLQE---WERKKLEQQQRKREEEQREQLKKEEEE---QERKQLAEK 182

PRK07352

F0F1 ATP synthase subunit B; Validated

1585-1667

1.79e-03

F0F1 ATP synthase subunit B; Validated

Pssm-ID: 180941 [Multi-domain] Cd Length: 174 Bit Score: 41.86 E-value: 1.79e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYV---KITQDDREMAQA-----EGKFAQKEETLAQRGEK-LSQEA 1655
Cdd:PRK07352   49 EERREAILQALKEAEERLRQAAQALAEAQQKLAQAQQeaeRIRADAKARAEAiraeiEKQAIEDMARLKQTAAAdLSAEQ 128

                          90
                  ....*....|...
gi 597709775 1656 EK-LAQKRKKLAK 1667
Cdd:PRK07352  129 ERvIAQLRREAAE 141

MAD

pfam05557

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...

1560-2043

1.93e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.

Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 43.58 E-value: 1.93e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1560 QVTEEQRHIQEEHKWARIhrkraRAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKItQDDREMAQAEGKFAQ 1639
Cdd:pfam05557   13 QLQNEKKQMELEHKRARI-----ELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEAL-REQAELNRLKKKYLE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1640 KEETLAQRGEKLSQEA-EKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVK---NILAQKVEELPQREQNLDWQEkela 1715
Cdd:pfam05557   87 ALNKKLNEKESQLADArEVISCLKNELSELRRQIQRAELELQSTNSELEELQerlDLLKAKASEAEQLRQNLEKQQ---- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1716 qeleelewdmEELSWKEEELNQEEGKLveekkklaeeeealawQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEE 1795
Cdd:pfam05557  163 ----------SSLAEAEQRIKELEFEI----------------QSQEQDSEIVKNSKSELARIPELEKELERLREHNKHL 216

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1796 ERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEK-------EKLAQRKENLLynKERLT 1868
Cdd:pfam05557  217 NENIENKLLLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTglnlrspEDLSRRIEQLQ--QREIV 294

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1869 HsKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETE--KKLVQVEDSLAKKQEKLAQEKMK-----LALEK 1941
Cdd:pfam05557  295 L-KEENSSLTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKalVRRLQRRVLLLTKERDGYRAILEsydkeLTMSN 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1942 AMVQGKKRLRGELDIAKEEKALNLEMkrlaeekmrlvegKETLSKGETPETSRQRKMTQVEQELFERKLSLEekillHED 2021
Cdd:pfam05557  374 YSPQLLERIEEAEDMTQKMQAHNEEM-------------EAQLSVAEEELGGYKQQAQTLERELQALRQQES-----LAD 435

                          490       500
                   ....*....|....*....|..
gi 597709775  2022 RILAMEESEIAKGKLEFTRGQR 2043
Cdd:pfam05557  436 PSYSKEEVDSLRRKLETLELER 457

PRK12705

hypothetical protein; Provisional

1760-1860

2.22e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 43.54 E-value: 2.22e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1760 REKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERwINSMEELTKNKMILYQKKNL 1839
Cdd:PRK12705   76 REELQREEERLVQKEEQLDARAEKLDNLENQLEEREKALSARELELEELEKQLDNELYR-VAGLTPEQARKLLLKLLDAE 154

                          90       100
                  ....*....|....*....|....*
gi 597709775 1840 AQEKK----NLAQEKEKLAQRKENL 1860
Cdd:PRK12705  155 LEEEKaqrvKKIEEEADLEAERKAQ 179

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

1594-2282

2.25e-03

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 43.56 E-value: 2.25e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1594 KLAQEEEKLAQ----EERQLAQEERKLaqayvkitQDDREMAQAEGKFAQKeetLAQRGEKLSQEAEKLAQKRKKLAKK- 1668
Cdd:pfam05483   82 KLYKEAEKIKKwkvsIEAELKQKENKL--------QENRKIIEAQRKAIQE---LQFENEKVSLKLEEEIQENKDLIKEn 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1669 -----W-----EKVAREEEKLAKKGGKLAEVKNI---LAQKVEELPQREQNLDWQEKELAQELEeleWDMEELSWKEEEL 1735
Cdd:pfam05483  151 natrhLcnllkETCARSAEKTKKYEYEREETRQVymdLNNNIEKMILAFEELRVQAENARLEMH---FKLKEDHEKIQHL 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1736 NQEEGKLVEEKKKLAEEEEAlawqreKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLgrkrEQLIEKKMKLAQK 1815
Cdd:pfam05483  228 EEEYKKEINDKEKQVSLLLI------QITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENL----KELIEKKDHLTKE 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1816 RERWINSMEELTKNKMILYQKKNLAQEK-KNLAQEKEklAQRKENllyNKERLTHSkkqLVQVKnklgmFNKILAQVEEK 1894
Cdd:pfam05483  298 LEDIKMSLQRSMSTQKALEEDLQIATKTiCQLTEEKE--AQMEEL---NKAKAAHS---FVVTE-----FEATTCSLEEL 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1895 LTQEKETVIKKKEKLA----ETEKKLVQVEDSLAKKQEK---LAQEKMKLALEKAMVQGKKRLRgelDIAKEEKALNLEM 1967
Cdd:pfam05483  365 LRTEQQRLEKNEDQLKiitmELQKKSSELEEMTKFKNNKeveLEELKKILAEDEKLLDEKKQFE---KIAEELKGKEQEL 441

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1968 KRLAEEKMRLVEGKET-LSKGETPETSRQRKMTQVEQELFERKLSLEE-----KILLHEDRILAMEESEIAkgkLEFTRG 2041
Cdd:pfam05483  442 IFLLQAREKEIHDLEIqLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEltahcDKLLLENKELTQEASDMT---LELKKH 518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2042 QRIFVQGQrklaKASRKLIKKRESLSKEPAKLNKILKALqkltRDERKLTQEEIKmtkmkralfvkerrlsieqSKLDIK 2121
Cdd:pfam05483  519 QEDIINCK----KQEERMLKQIENLEEKEMNLRDELESV----REEFIQKGDEVK-------------------CKLDKS 571

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2122 EWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKE---EKMTEEESKLARKHS---------EVILDDEEEGGIEEEEV 2189
Cdd:pfam05483  572 EENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNkniEELHQENKALKKKGSaenkqlnayEIKVNKLELELASAKQK 651

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2190 IPFLKRRWRKRKEAKRGDKPK-----EKFSSQVDE---VESE-----EHFSEEMESLL-------DELEKQESLSSEEEE 2249
Cdd:pfam05483  652 FEEIIDNYQKEIEDKKISEEKlleevEKAKAIADEavkLQKEidkrcQHKIAEMVALMekhkhqyDKIIEERDSELGLYK 731

                          730       740       750
                   ....*....|....*....|....*....|...
gi 597709775  2250 EREEEEEREEEEEREEEEERKEEEEGEEKQVEK 2282
Cdd:pfam05483  732 NKEQEQSSAKAALEIELSNIKAELLSLKKQLEI 764

Spc7

smart00787

Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...

1804-1975

2.37e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.

Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 42.70 E-value: 2.37e-03

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775   1804 QLIEKKMKLA------QKRERWINSMEELTKN-KMILYQKKN-LAQEKKNLAQEKEKLAQRKENLlynKERLTHSKKQLV 1875
Cdd:smart00787  113 LLMDKQFQLVktfarlEAKKMWYEWRMKLLEGlKEGLDENLEgLKEDYKLLMKELELLNSIKPKL---RDRKDALEEELR 189

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775   1876 QVKNKLGMFNKI----LAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLakkqEKLAQEKMKLALEKAMVQgKKRLR 1951
Cdd:smart00787  190 QLKQLEDELEDCdpteLDRAKEKLKKLLQEIMIKVKKLEELEEELQELESKI----EDLTNKKSELNTEIAEAE-KKLEQ 264

                           170       180
                    ....*....|....*....|....
gi 597709775   1952 GELDIAKEEKALNLEMKRLAEEKM 1975
Cdd:smart00787  265 CRGFTFKEIEKLKEQLKLLQSLTG 288

EmrA

COG1566

Multidrug resistance efflux pump EmrA [Defense mechanisms];

1575-1708

2.55e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];

Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 42.73 E-value: 2.55e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1575 ARIHRKRARAEKKRAQEErkLAQEEEKLAQEERQLAQEERkLAQAyvkitQDDREMAQAEGKFAQKEetlAQRGEKLSQE 1654
Cdd:COG1566    74 ARLDPTDLQAALAQAEAQ--LAAAEAQLARLEAELGAEAE-IAAA-----EAQLAAAQAQLDLAQRE---LERYQALYKK 142

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 597709775 1655 ----AEKLAQKRKKL--AKKWEKVAREEEKLAKKG----GKLAEVKNILAQKVEELPQREQNLD 1708
Cdd:COG1566   143 gavsQQELDEARAALdaAQAQLEAAQAQLAQAQAGlreeEELAAAQAQVAQAEAALAQAELNLA 206

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

1580-1807

2.78e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 2.78e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1580 KRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLaqayvkitqdDREMAQAEGKFAQKE-ETLAQRGEKLSQEAEKL 1658
Cdd:COG4913   238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAEL----------EYLRAALRLWFAQRRlELLEAELEELRAELARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1659 AQKRKKLAKKWEKVAREEEKLAKK-----GGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEE 1733
Cdd:COG4913   308 EAELERLEARLDALREELDELEAQirgngGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRA 387

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 597709775 1734 ELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEeellIQEkekLAQHKEKMPEEEERLgrkREQLIE 1807
Cdd:COG4913   388 EAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAE----IAS---LERRKSNIPARLLAL---RDALAE 451

COG1340

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

1641-1937

2.82e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 42.59 E-value: 2.82e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1641 EETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKK-------GGKLAEVKNILAQKVEELPQREQNLDWQEKE 1713
Cdd:COG1340    10 LEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQvkelreeAQELREKRDELNEKVKELKEERDELNEKLNE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1714 LAQELEELEWDMEELSWK-------EEELNQEEGKLveekkklaeeeealawQREKLS-EEETKLAQEeellIQEKEKLA 1785
Cdd:COG1340    90 LREELDELRKELAELNKAggsidklRKEIERLEWRQ----------------QTEVLSpEEEKELVEK----IKELEKEL 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1786 QHKEKMPEEEERLGRKREQLIEKKMKLAQKRERwinsMEELtknkmilyqkKNLAQEKKNLAQEKEKLA--QRKENLLYN 1863
Cdd:COG1340   150 EKAKKALEKNEKLKELRAELKELRKEAEEIHKK----IKEL----------AEEAQELHEEMIELYKEAdeLRKEADELH 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1864 KERLTHSKK------QLVQVKNKLGMFNKILAQVEekltqEKETVIKKKEKLAETEKKLVQVEDSLaKKQEKLAQEKMKL 1937
Cdd:COG1340   216 KEIVEAQEKadelheEIIELQKELRELRKELKKLR-----KKQRALKREKEKEELEEKAEEIFEKL-KKGEKLTTEELKL 289

PRK00106

ribonuclease Y;

1762-1953

2.92e-03

ribonuclease Y;

Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 42.93 E-value: 2.92e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1762 KLSEEETKLAQEEEL--LIQEKEKLAQHKEKMPEEEERLGRKrEQLIEKKMKLAQKRERwinsMEELTKNkmilyQKKNL 1839
Cdd:PRK00106   30 KEAAELTLLNAEQEAvnLRGKAERDAEHIKKTAKRESKALKK-ELLLEAKEEARKYREE----IEQEFKS-----ERQEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1840 AQEKKNLAQEKEKLAQRKENLlYNKERLTHSKKQLVQVKNK-LGMFNKILAQVEEKLTQEKETVIKKKEK------LAET 1912
Cdd:PRK00106  100 KQIESRLTERATSLDRKDENL-SSKEKTLESKEQSLTDKSKhIDEREEQVEKLEEQKKAELERVAALSQAeareiiLAET 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 597709775 1913 EKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGE 1953
Cdd:PRK00106  179 ENKLTHEIATRIREAEREVKDRSDKMAKDLLAQAMQRLAGE 219

mukB

PRK04863

chromosome partition protein MukB;

1599-1906

3.32e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.41 E-value: 3.32e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1599 EEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ-----------KEETLAQRGEKL------SQEAEKLAQK 1661
Cdd:PRK04863  836 EAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSAlnrllprlnllADETLADRVEEIreqldeAEEAKRFVQQ 915

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1662 RKKLAKKWEKVAR----EEEKLAKkggklaevkniLAQKVEELPQREQNLDWQEKElaqeleelewdmeeLSwkeeELNQ 1737
Cdd:PRK04863  916 HGNALAQLEPIVSvlqsDPEQFEQ-----------LKQDYQQAQQTQRDAKQQAFA--------------LT----EVVQ 966

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1738 eegklveekkklaeeeealawQREKLSEEET--KLAQEEELLIQEKEKLAQhkekmpEEEERLgRKREQLIEKKMKLAQK 1815
Cdd:PRK04863  967 ---------------------RRAHFSYEDAaeMLAKNSDLNEKLRQRLEQ------AEQERT-RAREQLRQAQAQLAQY 1018

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1816 RERWINSMEEL-TKNKMIlyqkKNLAQEKKNL-----AQEKEKLAQRKE----NLLYNKERLTHSKKQLVQVKNKLGMFN 1885
Cdd:PRK04863 1019 NQVLASLKSSYdAKRQML----QELKQELQDLgvpadSGAEERARARRDelhaRLSANRSRRNQLEKQLTFCEAEMDNLT 1094

                         330       340
                  ....*....|....*....|.
gi 597709775 1886 KILAQVEEKLTQEKETVIKKK 1906
Cdd:PRK04863 1095 KKLRKLERDYHEMREQVVNAK 1115

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

1484-1667

3.52e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 42.63 E-value: 3.52e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEdkkLKWEEWKQVWENMLSSKSKEQQykdeeevtleeevsregeEKEQQVTE 1563
Cdd:pfam15709  349 EVERKRREQEEQRRLQQEQLERAEKMREE---LELEQQRRFEEIRLRKQRLEEE------------------RQRQEEEE 407

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1564 EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQE-ERKLAQAYVKITqddrEMAQAEGKFAQKEE 1642
Cdd:pfam15709  408 RKQRLQLQAAQERARQQQEEFRRKLQELQRKKQQEEAERAEAEKQRQKElEMQLAEEQKRLM----EMAEEERLEYQRQK 483

                          170       180
                   ....*....|....*....|....*
gi 597709775  1643 TLAQrgEKLSQEAEKLAQKRKKLAK 1667
Cdd:pfam15709  484 QEAE--EKARLEAEERRQKEEEAAR 506

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

1492-2158

3.81e-03

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.90 E-value: 3.81e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1492 EEEKLHQAGEKLSPEEEMLQED-KKLKWEEWKqvwenmLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQE 1570
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEfNTLESAELR------LSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1571 EHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEER--QLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRG 1648
Cdd:pfam12128  302 KRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADieTAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRR 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1649 EKLSQE-AEKLAQKRKKLAKKWEKVAREeeklakkggkLAEVKNIL----AQKVEELPQREQNLDWQEKELAQELEELEW 1723
Cdd:pfam12128  382 SKIKEQnNRDIAGIKDKLAKIREARDRQ----------LAVAEDDLqaleSELREQLEAGKLEFNEEEYRLKSRLGELKL 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1724 DMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAwQREKLSEEETKLA----QEEELLIQEKEKLAQHKEKMPEEEERLG 1799
Cdd:pfam12128  452 RLNQATATPELLLQLENFDERIERAREEQEAANA-EVERLQSELRQARkrrdQASEALRQASRRLEERQSALDELELQLF 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1800 RKREQLIEKKMKLAQKRERWINSM---------------------EELTKNKMILYQKKNLAQEKKNLAQE-KEKLAQRK 1857
Cdd:pfam12128  531 PQAGTLLHFLRKEAPDWEQSIGKVispellhrtdldpevwdgsvgGELNLYGVKLDLKRIDVPEWAASEEElRERLDKAE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1858 ENLLYNKERLTHSKKQLVQVKNKLGMFNK-------ILAQVEE---KLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ 1927
Cdd:pfam12128  611 EALQSAREKQAAAEEQLVQANGELEKASReetfartALKNARLdlrRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQ 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1928 EKLAQEKMKLALEK----------AMVQGKKRLRGELD---------IAKEEKALNLEMKRLAEEKMRLVEGK----ETL 1984
Cdd:pfam12128  691 LKQLDKKHQAWLEEqkeqkreartEKQAYWQVVEGALDaqlallkaaIAARRSGAKAELKALETWYKRDLASLgvdpDVI 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1985 SKGETPETSRQRKMTQVE---QELFERKLSLEEKILLHEDRiLAMEESEIaKGKLEFTRGQRIFVQGQRKLAKAsrKLIK 2061
Cdd:pfam12128  771 AKLKREIRTLERKIERIAvrrQEVLRYFDWYQETWLQRRPR-LATQLSNI-ERAISELQQQLARLIADTKLRRA--KLEM 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  2062 KRESLSKEPAKLNKILKALQ----KLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEW--DF-----SEKRS 2130
Cdd:pfam12128  847 ERKASEKQQVRLSENLRGLRcemsKLATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYveHFknviaDHSGS 926

                          730       740
                   ....*....|....*....|....*...
gi 597709775  2131 ELTKDEKKLARKQRKLANKMRRMINKEE 2158
Cdd:pfam12128  927 GLAETWESLREEDHYQNDKGIRLLDYRK 954

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

1558-1661

3.89e-03

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.18 E-value: 3.89e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1558 EQQVTEEQRHIQEEHkwarihRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Cdd:cd16269   190 DQALTEKEKEIEAER------AKAEAAEQERKLLEEQQRELEQKLEDQERSYEEHLRQLKEKMEEERENLLKEQERALES 263

                          90       100
                  ....*....|....*....|....
gi 597709775 1638 AQKEETLAQRgEKLSQEAEKLAQK 1661
Cdd:cd16269   264 KLKEQEALLE-EGFKEQAELLQEE 286

DR0291

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

1762-1942

4.02e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 4.02e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1762 KLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKrerwinsmeeltknkmilyqKKNLAQ 1841
Cdd:COG1579    11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRL--------------------ELEIEE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775 1842 EKKNLAQEKEKLAQRKENllynKErLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVED 1921
Cdd:COG1579    71 VEARIKKYEEQLGNVRNN----KE-YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA 145

                         170       180
                  ....*....|....*....|.
gi 597709775 1922 SLAKKQEKLAQEKMKLALEKA 1942
Cdd:COG1579   146 ELDEELAELEAELEELEAERE 166

RNase_Y_N

pfam12072

RNase Y N-terminal region;

1577-1699

4.12e-03

RNase Y N-terminal region;

Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 41.02 E-value: 4.12e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1577 IHRKRARAEKKRAQEERKLAQEEEKLAQEERQLaqeerklaqayvkitqdDREMAQAEgkfaQKEETLAQRGEKLSQEAE 1656
Cdd:pfam12072   62 IHKLRAEAERELKERRNELQRQERRLLQKEETL-----------------DRKDESLE----KKEESLEKKEKELEAQQQ 120

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 597709775  1657 KLAQKRKKLAKKWEKVAREEEKLAkkGGKLAEVKNILAQKVEE 1699
Cdd:pfam12072  121 QLEEKEEELEELIEEQRQELERIS--GLTSEEAKEILLDEVEE 161

WD40

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...

463-635

4.71e-03

Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 41.55 E-value: 4.71e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  463 HFGAVLALSTLSGGifggqgnSLLCSYGMDDYVHL----SEAVLDGVKVQLRPLASILSSCHLTHLIllpkSVGaitETN 538
Cdd:cd00200     8 HTGGVTCVAFSPDG-------KLLATGSGDGTIKVwdleTGELLRTLKGHTGPVRDVAASADGTYLA----SGS---SDK 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  539 CLRLWKFhdflssgsqNGLKFIETLPLHLCAITSFDVCLSLSLFVTGSADGSVRIWDFH-GRLIGILDSslHFGPVCFan 617
Cdd:cd00200    74 TIRLWDL---------ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVEtGKCLTTLRG--HTDWVNS-- 140

                         170
                  ....*....|....*...
gi 597709775  618 drgdllVTFNQSLYLVSC 635
Cdd:cd00200   141 ------VAFSPDGTFVAS 152

DUF6033

pfam19498

Protein of unknown function (DUF6033); This family of proteins is functionally uncharacterized. ...

1585-1700

4.78e-03

Protein of unknown function (DUF6033); This family of proteins is functionally uncharacterized. This family of proteins is primarily found in Clostridia. Proteins in this family are typically between 212 and 271 amino acids in length.

Pssm-ID: 437330 Cd Length: 204 Bit Score: 41.12 E-value: 4.78e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDdremaqaeGK---FAQKEETLAQRGEKLSQEAEKLAQK 1661
Cdd:pfam19498   63 ESYRKKYEGIIANAASKLSQLKSSLASSGANVKGFGMQVNDD--------GTasyFAVLEKSSAAQKERIEKKRAKKKEE 134

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 597709775  1662 RKKLAKKWEKVAReEEKLAKKGGKLAEVKNILAQKVEEL 1700
Cdd:pfam19498  135 KKAEEKKAEKKKR-EERLEKAKEEKEETVTVTASSIEEL 172

Surf_Exclu_PgrA

TIGR04320

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...

1595-1700

4.83e-03

Pssm-ID: 275124 [Multi-domain] Cd Length: 356 Bit Score: 42.02 E-value: 4.83e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597709775  1595 LAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEK-LAQKRKKLAKKwekva 1673
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTAQNnLATAQAALANA----- 330

                           90       100
                   ....*....|....*....|....*..
gi 597709775  1674 reEEKLAKKGGKLAEVKNILAQKVEEL 1700
Cdd:TIGR04320  331 --EARLAKAKEALANLNADLAKKQAAL 355

tolA_full