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Conserved domains on  [gi|13994360|ref|NP_114163|]
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keratin-associated protein 1-5 [Homo sapiens]

Protein Classification

Keratin_B2 domain-containing protein( domain architecture ID 12021880)

Keratin_B2 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
1-170 4.69e-39

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


:

Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 130.68  E-value: 4.69e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13994360     1 MTCCQTSFCGYPSFSISGTCGSSCCQPSCCETSCCQPRSCQTSFCgfpSFSTSGTCSSSCCQPSCCETSCCQPSCCETSC 80
Cdd:pfam01500   1 MACCGTSFCGFPTCSTGGTCGSGCCQPCCCQSSCCRPSCCQTSCC---QPTTFQSSCCRPTCQPCCQTSCCQPTCCQTSS 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13994360    81 CQPSCCQISSCgtgcgigggisygQEGSSGAVSTRIRWCRPDSRVEGTYLPPCCVVSCTPPSCCQLHHAQASCCRPSYCG 160
Cdd:pfam01500  78 CQTGCGGIGYG-------------QEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCG 144
                         170
                  ....*....|
gi 13994360   161 QSCCRPVCCC 170
Cdd:pfam01500 145 QSCCRPACCC 154
 
Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
1-170 4.69e-39

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 130.68  E-value: 4.69e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13994360     1 MTCCQTSFCGYPSFSISGTCGSSCCQPSCCETSCCQPRSCQTSFCgfpSFSTSGTCSSSCCQPSCCETSCCQPSCCETSC 80
Cdd:pfam01500   1 MACCGTSFCGFPTCSTGGTCGSGCCQPCCCQSSCCRPSCCQTSCC---QPTTFQSSCCRPTCQPCCQTSCCQPTCCQTSS 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13994360    81 CQPSCCQISSCgtgcgigggisygQEGSSGAVSTRIRWCRPDSRVEGTYLPPCCVVSCTPPSCCQLHHAQASCCRPSYCG 160
Cdd:pfam01500  78 CQTGCGGIGYG-------------QEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCG 144
                         170
                  ....*....|
gi 13994360   161 QSCCRPVCCC 170
Cdd:pfam01500 145 QSCCRPACCC 154
 
Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
1-170 4.69e-39

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 130.68  E-value: 4.69e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13994360     1 MTCCQTSFCGYPSFSISGTCGSSCCQPSCCETSCCQPRSCQTSFCgfpSFSTSGTCSSSCCQPSCCETSCCQPSCCETSC 80
Cdd:pfam01500   1 MACCGTSFCGFPTCSTGGTCGSGCCQPCCCQSSCCRPSCCQTSCC---QPTTFQSSCCRPTCQPCCQTSCCQPTCCQTSS 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13994360    81 CQPSCCQISSCgtgcgigggisygQEGSSGAVSTRIRWCRPDSRVEGTYLPPCCVVSCTPPSCCQLHHAQASCCRPSYCG 160
Cdd:pfam01500  78 CQTGCGGIGYG-------------QEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCG 144
                         170
                  ....*....|
gi 13994360   161 QSCCRPVCCC 170
Cdd:pfam01500 145 QSCCRPACCC 154
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
24-87 9.51e-05

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 38.13  E-value: 9.51e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13994360    24 CCQPSCCETSCCQPRSCqtsfcgfpsfstsgtcsssccQPSCCETSCCQPSCCETSCCQPSCCQ 87
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCC---------------------QPSCCQPSCCQPSCCRPSCCRSSCCQ 43
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
133-169 3.36e-03

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 33.89  E-value: 3.36e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 13994360   133 CCVVSCTPPSCCQLHHAQASCCRPSYCGQSCCRPVCC 169
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCC 37
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
3-45 3.50e-03

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 33.89  E-value: 3.50e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 13994360     3 CCQTSfCGYPSFSISGTCGSSCCQPSCCETSCCQPRSCQTSFC 45
Cdd:pfam13885   1 CCQPS-CCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCC 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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