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Conserved domains on  [gi|14141960|ref|NP_115401|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Tinamus major]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.62e-52

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 164.54  E-value: 2.62e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    1 MMYFVSFLGVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSLAAEPYVE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960   81 AWGDWRVLGYGMGFMVVVLMGGVVWDLVGSGGWWVGTVDCVGGGLVRVDFSGVAMFYSWGAGMFMVAGWGLFLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 14141960  161 LVRGLSCGAVRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.62e-52

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 164.54  E-value: 2.62e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    1 MMYFVSFLGVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSLAAEPYVE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960   81 AWGDWRVLGYGMGFMVVVLMGGVVWDLVGSGGWWVGTVDCVGGGLVRVDFSGVAMFYSWGAGMFMVAGWGLFLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 14141960  161 LVRGLSCGAVRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 4.96e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.12  E-value: 4.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    17 LAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSL-AAEPYVEAWGDWRVLGYGMGFM 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 14141960    96 VVVLMGGVVWDLVGSGGWWVGTVDCVGgglvRVDFSGVAMFYSWgAGMFMVAGWGLFLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.62e-52

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 164.54  E-value: 2.62e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    1 MMYFVSFLGVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSLAAEPYVE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960   81 AWGDWRVLGYGMGFMVVVLMGGVVWDLVGSGGWWVGTVDCVGGGLVRVDFSGVAMFYSWGAGMFMVAGWGLFLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 14141960  161 LVRGLSCGAVRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.64e-51

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 162.61  E-value: 1.64e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    1 MMYFVSFLGVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSLAAEPYVE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960   81 AWGDWRVLGYGMGFMVVVLMGGVVW-DLVGSGGWWVGTVDCVGGGLVRVDFSGVAMFYSWGAGMFMVAGWGLFLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVgGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 14141960  160 ELVRGLSCGAVRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 3.58e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 153.85  E-value: 3.58e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    1 MMYFVSFLGVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSLAAEPYVE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960   81 AWGDWRVLGYGMGFMVVVLMGGVVWDLVGSGGWWVgTVDCVGGGLVRVDFSGVAMFYSWGAGMFMVAGWGLFLTLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLF-TNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 14141960  161 LVRGLSCGAVRAV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-164 1.02e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 104.50  E-value: 1.02e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    1 MMYFVSFLGVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSLAAEPYVE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960   81 AWGD-WRVLG----------YGMGFMVVVLMGGVVWDLVGSGGWWVgtVDCVGGGLVRVDFSGVAMFYSWGAGMFMVAGW 149
Cdd:MTH00109  82 TWVSnKVVLGalllgllmelLLVLYVLKDDEVEVVFNFNGLGDWVI--YDTGGSGFFSEDAMGVAALYSYGTWLVVVTGW 159

                        170
                 ....*....|....*
gi 14141960  150 GLFLTLFVVLELVRG 164
Cdd:MTH00109 160 SLFIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 3.87e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 95.06  E-value: 3.87e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    1 MMYFVSFLGVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSLAAEPYVE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960   81 AWGDWRVLGYGMGFMVVVLMGGVVWDLVGSGGWWVGtvdcvGGGLVRVDFSGVAMFYSWGAGMFMVAGWGLFLTLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMG-----VDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 14141960  161 LVRGLSCGAVRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-172 3.67e-12

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 61.07  E-value: 3.67e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    1 MMYFVSFlgVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSLAAE--PY 78
Cdd:MTH00045   1 MVFYLFL--ILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAEryPS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960   79 VEAWGDWRVLGYGMGFMVVVLMGGVVWdlvgsggWWVGTVDCVGGglvrVDFSGVAMFYSWGAGMFMVAGWGLFLTLFVV 158
Cdd:MTH00045  79 VSNLGEVLVLSLLLSLWVFISFDNFLE-------LSNNNWSLVSL----SDLVGSSELYNSGGLYLLLGGFILLVALVVA 147

                        170
                 ....*....|....
gi 14141960  159 LELVRGLSCGAVRA 172
Cdd:MTH00045 148 LVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 4.96e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.12  E-value: 4.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14141960    17 LAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSL-AAEPYVEAWGDWRVLGYGMGFM 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 14141960    96 VVVLMGGVVWDLVGSGGWWVGTVDCVGgglvRVDFSGVAMFYSWgAGMFMVAGWGLFLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 30-74 9.27e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 37.86  E-value: 9.27e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 14141960   30 MGLVMGSVVGCGWLlslgvsfvSLVLFLVYLGGMLVVFVYCVSLA 74
Cdd:MTH00166  35 ISLLLGLMMKSFWF--------SYILFLIFLGGMLVLFIYITSLA 71
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 3.75e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 36.24  E-value: 3.75e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 14141960    7 FLGVCFVLGALAVASNPSPQYGVMGLVMGSVVGCGWLLSLGVSFVSLVLFLVYLGGMLVVFVYCVSL 73
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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