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Conserved domains on  [gi|15236755|ref|NP_194960|]
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Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459648)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
113-194 1.10e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


:

Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.15  E-value: 1.10e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYcERAmLSESGRDGELLSMYGDLIWKNhGDGVRAQSYYDQAVQSS 192
Cdd:COG3063  14 YYEKALELDPDNADALNNLGLLLLE-QGRYDEAIAL-EKA-LKLDPNNAEALLNLAELLLEL-GDYDEALAYLERALELD 89


                ..
gi 15236755 193 PD 194
Cdd:COG3063  90 PS 91
 
Name Accession Description Interval E-value
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
113-194 1.10e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.15  E-value: 1.10e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYcERAmLSESGRDGELLSMYGDLIWKNhGDGVRAQSYYDQAVQSS 192
Cdd:COG3063  14 YYEKALELDPDNADALNNLGLLLLE-QGRYDEAIAL-EKA-LKLDPNNAEALLNLAELLLEL-GDYDEALAYLERALELD 89


                ..
gi 15236755 193 PD 194
Cdd:COG3063  90 PS 91
 
Name Accession Description Interval E-value
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
113-194 1.10e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.15  E-value: 1.10e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYcERAmLSESGRDGELLSMYGDLIWKNhGDGVRAQSYYDQAVQSS 192
Cdd:COG3063  14 YYEKALELDPDNADALNNLGLLLLE-QGRYDEAIAL-EKA-LKLDPNNAEALLNLAELLLEL-GDYDEALAYLERALELD 89


                ..
gi 15236755 193 PD 194
Cdd:COG3063  90 PS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 113-195 1.37e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.76  E-value: 1.37e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYCERAmLSESGRDGELLSMYGdLIWKNHGDGVRAQSYYDQAVQSS 192
Cdd:COG4235  39 AYEKALRLDPDNADALLDLAEALLA-AGDTEEAEELLERA-LALDPDNPEALYLLG-LAAFQQGDYAEAIAAWQKLLALL 115


                ...
gi 15236755 193 PDD 195
Cdd:COG4235 116 PAD 118
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 113-193 4.76e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.56  E-value: 4.76e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYCERAmLSESGRDGELLSMYGDLIWKNhGDGVRAQSYYDQAVQSS 192
Cdd:COG5010  76 LLEQALQLDPNNPELYYNLALLYSR-SGDKDEAKEYYEKA-LALSPDNPNAYSNLAALLLSL-GQDDEAKAALQRALGTS 152


                .
gi 15236755 193 P 193
Cdd:COG5010 153 P 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 113-209 5.61e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.02  E-value: 5.61e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYCERAmLSESGRDGELLSMYGdLIWKNHGDGVRAQSYYDQAVQSS 192
Cdd:COG4783  26 LLEKALELDPDNPEAFALLGEILLQ-LGDLDEAIVLLHEA-LELDPDEPEARLNLG-LALLKAGDYDEALALLEKALKLD 102

                        90
                ....*....|....*..
gi 15236755 193 PDDCNVLASYARFLWDA 209
Cdd:COG4783 103 PEHPEAYLRLARAYRAL 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
113-207 7.76e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.60  E-value: 7.76e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYCERAmLSESGRDGELLSMYGdLIWKNHGDGVRAQSYYDQAVQSS 192
Cdd:COG0457  64 DYEQALELDPDDAEALNNLGLALQA-LGRYEEALEDYDKA-LELDPDDAEALYNLG-LALLELGRYDEAIEAYERALELD 140

                        90
                ....*....|....*
gi 15236755 193 PDDCNVLASYARFLW 207
Cdd:COG0457 141 PDDADALYNLGIALE 155
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 114-206 1.12e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 1.12e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 114 YEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYCERAmLSESGRDGELLSMYGDLIWKNHGDGvRAQSYYDQAVQSSP 193
Cdd:COG4235   6 LRQALAANPNDAEGWLLLGRAYLR-LGRYDEALAAYEKA-LRLDPDNADALLDLAEALLAAGDTE-EAEELLERALALDP 82

                        90
                ....*....|...
gi 15236755 194 DDCNVLASYARFL 206
Cdd:COG4235  83 DNPEALYLLGLAA 95
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 113-209 1.52e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 1.52e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARFLKEvKGDGRKAEEYCERAmLSESGRDGELLSMYGDLIWKNhGDGVRAQSYYDQAVQSS 192
Cdd:COG2956  98 LLEKLLELDPDDAEALRLLAEIYEQ-EGDWEKAIEVLERL-LKLGPENAHAYCELAELYLEQ-GDYDEAIEALEKALKLD 174

                        90
                ....*....|....*..
gi 15236755 193 PDDCNVLASYARFLWDA 209
Cdd:COG2956 175 PDCARALLLLAELYLEQ 191
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 113-206 2.04e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.56  E-value: 2.04e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 113 YYEEMIQRYPGDTLLLSNYARfLKEVKGDGRKAEEYCERAmLSESGRDGELLSMYGDlIWKNHGDGVRAQSYYDQAVQSS 192
Cdd:COG2956 132 VLERLLKLGPENAHAYCELAE-LYLEQGDYDEAIEALEKA-LKLDPDCARALLLLAE-LYLEQGDYEEAIAALERALEQD 208

                        90
                ....*....|....
gi 15236755 193 PDDCNVLASYARFL 206
Cdd:COG2956 209 PDYLPALPRLAELY 222
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 126-207 4.02e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 36.86  E-value: 4.02e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236755 126 LLLSNYARFLKEVKGDGRKAEEYCERAmLSESGRDGELLSMYGdLIWKNHGDGVRAQSYYDQAVQSSPDDCNVLASYARF 205
Cdd:COG5010  54 FAIESPSDNLYNKLGDFEESLALLEQA-LQLDPNNPELYYNLA-LLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAAL 131


                ..
gi 15236755 206 LW 207
Cdd:COG5010 132 LL 133
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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