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Conserved domains on  [gi|19075474|ref|NP_587974|]
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mitochondrial LYR family protein Lyr2 [Schizosaccharomyces pombe]

Protein Classification

LYR motif-containing protein( domain architecture ID 10526530)

LYR motif-containing protein plays a key role in the assembly and function of complexes I, II, and III; LYR motifs are molecular signatures of specific recipient Fe-S proteins or accessory factors that assist Fe-S cluster delivery

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Complex1_LYR pfam05347
Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the ...
 16-72 1.14e-06

Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the higher eukaryotic NADH dehydrogenase complex. In Saccharomyces cerevisiae, the Isd11 protein has been shown to play a role in Fe/S cluster biogenesis in mitochondria. We have named this family LYR after a highly conserved tripeptide motif close to the N-terminus of these proteins.


:

Pssm-ID: 428432  Cd Length: 59  Bit Score: 44.88  E-value: 1.14e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 19075474    16 ECLQVYRSLLRSCDEIQNRPLGEKLSKIVKARTRHYQNVGNAYKAEALLKDAKKQCE 72
Cdd:pfam05347   2 QVLSLYRALLRAARKFPDYNFREYFRRRIRDEFRKNKDLTDPEKIEKLLKEGKEELE 58
 
Name Accession Description Interval E-value
Complex1_LYR pfam05347
Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the ...
 16-72 1.14e-06

Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the higher eukaryotic NADH dehydrogenase complex. In Saccharomyces cerevisiae, the Isd11 protein has been shown to play a role in Fe/S cluster biogenesis in mitochondria. We have named this family LYR after a highly conserved tripeptide motif close to the N-terminus of these proteins.


Pssm-ID: 428432  Cd Length: 59  Bit Score: 44.88  E-value: 1.14e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 19075474    16 ECLQVYRSLLRSCDEIQNRPLGEKLSKIVKARTRHYQNVGNAYKAEALLKDAKKQCE 72
Cdd:pfam05347   2 QVLSLYRALLRAARKFPDYNFREYFRRRIRDEFRKNKDLTDPEKIEKLLKEGKEELE 58
 
Name Accession Description Interval E-value
Complex1_LYR pfam05347
Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the ...
 16-72 1.14e-06

Complex 1 protein (LYR family); Proteins in this family include an accessory subunit of the higher eukaryotic NADH dehydrogenase complex. In Saccharomyces cerevisiae, the Isd11 protein has been shown to play a role in Fe/S cluster biogenesis in mitochondria. We have named this family LYR after a highly conserved tripeptide motif close to the N-terminus of these proteins.


Pssm-ID: 428432  Cd Length: 59  Bit Score: 44.88  E-value: 1.14e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 19075474    16 ECLQVYRSLLRSCDEIQNRPLGEKLSKIVKARTRHYQNVGNAYKAEALLKDAKKQCE 72
Cdd:pfam05347   2 QVLSLYRALLRAARKFPDYNFREYFRRRIRDEFRKNKDLTDPEKIEKLLKEGKEELE 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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