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Conserved domains on  [gi|19113973|ref|NP_593061|]
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translocon gamma subunit Sss1 [Schizosaccharomyces pombe]

Protein Classification

preprotein translocase subunit SecE( domain architecture ID 1575)

preprotein translocase subunit SecE is an essential subunit of the Sec protein translocation channel SecYEG and it clamps together the 2 halves of SecY; may contact the channel plug during translocation

CATH:  1.20.5.1030
Gene Ontology:  GO:0043952|GO:0065002|GO:0006605
SCOP:  4005885
TCDB:  3.A.5

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
secE super family cl00481
preprotein translocase subunit SecE; Reviewed
 8-69 4.38e-16

preprotein translocase subunit SecE; Reviewed


The actual alignment was detected with superfamily member PTZ00478:

Pssm-ID: 469787  Cd Length: 81  Bit Score: 65.50  E-value: 4.38e-16
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19113973   8 LFQIPKNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLIHIPINKVLVGG 69
Cdd:PTZ00478 19 VVSGVQEFANDSRRLIRKCTKPDAKEYTNIAYACSVGFFIMGFIGYSIKLVFIPINNIIVGS 80
 
Name Accession Description Interval E-value
PTZ00478 PTZ00478
Sec superfamily; Provisional
 8-69 4.38e-16

Sec superfamily; Provisional


Pssm-ID: 185656  Cd Length: 81  Bit Score: 65.50  E-value: 4.38e-16
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19113973   8 LFQIPKNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLIHIPINKVLVGG 69
Cdd:PTZ00478 19 VVSGVQEFANDSRRLIRKCTKPDAKEYTNIAYACSVGFFIMGFIGYSIKLVFIPINNIIVGS 80
secE_euk_arch TIGR00327
protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; This model describes ...
 12-67 1.80e-14

protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; This model describes archaeal SEC61-like and eukaryotic SEC61 but not bacterial secE proteins, for which a Pfam pfam00584 (SecE) has been created. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273016  Cd Length: 61  Bit Score: 60.93  E-value: 1.80e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 19113973   12 PKNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLIHIPINKVLV 67
Cdd:TIGR00327  6 PVEFIKEGTRVLAVCKKPDLEEYLKVAKVTGIGIIIVGIIGYIIKIIAIPIRGVLK 61
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 13-66 5.75e-12

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 54.36  E-value: 5.75e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 19113973   13 KNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLIH-IPINKVL 66
Cdd:pfam00584  1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFsILINLLL 55
Sss1 COG2443
Preprotein translocase subunit Sss1 [Intracellular trafficking, secretion, and vesicular ...
 5-58 3.27e-07

Preprotein translocase subunit Sss1 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441984  Cd Length: 63  Bit Score: 42.51  E-value: 3.27e-07
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....
gi 19113973  5 ADDLFQIPKNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLI 58
Cdd:COG2443  2 AIKIQEKLKELLKDYKRVLKLARKPDKEEFLQIAKITGLGILLIGLIGFIIYLI 55
 
Name Accession Description Interval E-value
PTZ00478 PTZ00478
Sec superfamily; Provisional
 8-69 4.38e-16

Sec superfamily; Provisional


Pssm-ID: 185656  Cd Length: 81  Bit Score: 65.50  E-value: 4.38e-16
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19113973   8 LFQIPKNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLIHIPINKVLVGG 69
Cdd:PTZ00478 19 VVSGVQEFANDSRRLIRKCTKPDAKEYTNIAYACSVGFFIMGFIGYSIKLVFIPINNIIVGS 80
secE_euk_arch TIGR00327
protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; This model describes ...
 12-67 1.80e-14

protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; This model describes archaeal SEC61-like and eukaryotic SEC61 but not bacterial secE proteins, for which a Pfam pfam00584 (SecE) has been created. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273016  Cd Length: 61  Bit Score: 60.93  E-value: 1.80e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 19113973   12 PKNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLIHIPINKVLV 67
Cdd:TIGR00327  6 PVEFIKEGTRVLAVCKKPDLEEYLKVAKVTGIGIIIVGIIGYIIKIIAIPIRGVLK 61
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 13-66 5.75e-12

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 54.36  E-value: 5.75e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 19113973   13 KNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLIH-IPINKVL 66
Cdd:pfam00584  1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFsILINLLL 55
Sss1 COG2443
Preprotein translocase subunit Sss1 [Intracellular trafficking, secretion, and vesicular ...
 5-58 3.27e-07

Preprotein translocase subunit Sss1 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441984  Cd Length: 63  Bit Score: 42.51  E-value: 3.27e-07
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....
gi 19113973  5 ADDLFQIPKNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLI 58
Cdd:COG2443  2 AIKIQEKLKELLKDYKRVLKLARKPDKEEFLQIAKITGLGILLIGLIGFIIYLI 55
secE PRK09400
preprotein translocase subunit SecE; Reviewed
 4-58 3.01e-06

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236497  Cd Length: 61  Bit Score: 39.84  E-value: 3.01e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 19113973   4 NADDLFQIPKNFYKEGSHFIKRCVKPDRKEFLSISKAVATGFVLMGLIGYIIKLI 58
Cdd:PRK09400  2 SSNKLQENVKNFLEDYKRVLKVARKPTREEFLLVAKVTGLGILLIGLIGFIIYLI 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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