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Conserved domains on  [gi|19114213|ref|NP_593301|]
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anaphase-promoting complex TPR lobe subcomplex subunit Cut9/Apc6 [Schizosaccharomyces pombe]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 13798475)

tetratricopeptide repeat (TPR) protein with an ANAPC3 (anaphase-promoting complex, subunit 3) domain, such as Saccharomyces cerevisiae anaphase-promoting complex/cyclosome (APC/C) subunits CDC16 and CDC27

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  21153002|10517866|30708253|16896351
SCOP:  4001344

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 96-176 1.18e-20

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


:

Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 86.54  E-value: 1.18e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213    96 MQQQYKCAAFVGEKVL-DITGNPNDAFWLAQVYCCTGDYARAKCLLTKEDLYNRSSACRYLAAFCLVKLYDWQGALNLLG 174
Cdd:pfam12895   1 DQHQYKNAIFLAERLLaAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLGCRYLFAQCLLKLKKYDEALDALG 80


                  ..
gi 19114213   175 ET 176
Cdd:pfam12895  81 KA 82
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 330-578 5.08e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.48  E-value: 5.08e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 330 KILEIDPYNLDVYpLHLASLHES-GEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGP 408
Cdd:COG2956  33 EALELDPETVEAH-LALGNLYRRrGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 409 AWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNK 488
Cdd:COG2956 112 ALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 489 SDMQTAINHFQNALllvkktqSNEKPWAATWANLGHAYRKLKMYDAAIDALNQgLLLSTNDANVHTAIALVYLHKKIPGL 568
Cdd:COG2956 192 GDYEEAIAALERAL-------EQDPDYLPALPRLAELYEKLGDPEEALELLRK-ALELDPSDDLLLALADLLERKEGLEA 263

                       250
                ....*....|
gi 19114213 569 AITHLHESLA 578
Cdd:COG2956 264 ALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 123-335 6.16e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.57  E-value: 6.16e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 123 LAQVYCCTGDYARAKCLLTK-EDLYNRSSACRYLAAFCLVKLYDWQGALNLLgetnpfrkdeknaNKLLMQDGGiklEAS 201
Cdd:COG2956  82 LAQDYLKAGLLDRAEELLEKlLELDPDDAEALRLLAEIYEQEGDWEKAIEVL-------------ERLLKLGPE---NAH 145

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 202 MCYLRGQVYTNLSNFDRAKECYKEALMVDAKCYEAFDQLVsnHLLTADEEWDLVLKLnYSTYSKEDAAFLRSLYMLkLNK 281
Cdd:COG2956 146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLA--ELYLEQGDYEEAIAA-LERALEQDPDYLPALPRL-AEL 221

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 19114213 282 TSHEDELRRAEDYLSSINGLEKSSDLLLCKADTLFVRSRFIDVLAITTKILEID 335
Cdd:COG2956 222 YEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
 
Name Accession Description Interval E-value
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 96-176 1.18e-20

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 86.54  E-value: 1.18e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213    96 MQQQYKCAAFVGEKVL-DITGNPNDAFWLAQVYCCTGDYARAKCLLTKEDLYNRSSACRYLAAFCLVKLYDWQGALNLLG 174
Cdd:pfam12895   1 DQHQYKNAIFLAERLLaAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLGCRYLFAQCLLKLKKYDEALDALG 80


                  ..
gi 19114213   175 ET 176
Cdd:pfam12895  81 KA 82
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 330-578 5.08e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.48  E-value: 5.08e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 330 KILEIDPYNLDVYpLHLASLHES-GEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGP 408
Cdd:COG2956  33 EALELDPETVEAH-LALGNLYRRrGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 409 AWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNK 488
Cdd:COG2956 112 ALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 489 SDMQTAINHFQNALllvkktqSNEKPWAATWANLGHAYRKLKMYDAAIDALNQgLLLSTNDANVHTAIALVYLHKKIPGL 568
Cdd:COG2956 192 GDYEEAIAALERAL-------EQDPDYLPALPRLAELYEKLGDPEEALELLRK-ALELDPSDDLLLALADLLERKEGLEA 263

                       250
                ....*....|
gi 19114213 569 AITHLHESLA 578
Cdd:COG2956 264 ALALLERQLR 273
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 205-582 1.11e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 71.27  E-value: 1.11e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   205 LRGQVYTNLSNFDRAKECYKEALMVDAKCYEAFDQLvsnhlltadeewdlvLKLNYSTySKEDAAFLRSLYMLKLNKTSh 284
Cdd:TIGR02917 470 LLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANL---------------ARIDIQE-GNPDDAIQRFEKVLTIDPKN- 532

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   285 edelrraedyLSSINGLeksSDLLLCKADTLfvrsrfiDVLAITTKILEIDPYNLDVYPLHLASLHESGEKNKLYLISND 364
Cdd:TIGR02917 533 ----------LRAILAL---AGLYLRTGNEE-------EAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNE 592

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   365 LVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGthlpy 444
Cdd:TIGR02917 593 AADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPD----- 667

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   445 lFLGMQHMQlGNILLANEYLQSSYALFQY-------DPLLLNELGVVAFNKSDMQTAINHFQNALllvkKTQSNekpwAA 517
Cdd:TIGR02917 668 -NTEAQIGL-AQLLLAAKRTESAKKIAKSlqkqhpkAALGFELEGDLYLRQKDYPAAIQAYRKAL----KRAPS----SQ 737

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19114213   518 TWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPN 582
Cdd:TIGR02917 738 NAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802
TPR_12 pfam13424
Tetratricopeptide repeat;
477-543 2.59e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.46  E-value: 2.59e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19114213   477 LLNELGVVAFNKSDMQTAINHFQNALLLVKKTQSNEKPWAATWA-NLGHAYRKLKMYDAAIDALNQGL 543
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLlNLGRLYLELGRYEEALELLERAL 72
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 123-335 6.16e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.57  E-value: 6.16e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 123 LAQVYCCTGDYARAKCLLTK-EDLYNRSSACRYLAAFCLVKLYDWQGALNLLgetnpfrkdeknaNKLLMQDGGiklEAS 201
Cdd:COG2956  82 LAQDYLKAGLLDRAEELLEKlLELDPDDAEALRLLAEIYEQEGDWEKAIEVL-------------ERLLKLGPE---NAH 145

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 202 MCYLRGQVYTNLSNFDRAKECYKEALMVDAKCYEAFDQLVsnHLLTADEEWDLVLKLnYSTYSKEDAAFLRSLYMLkLNK 281
Cdd:COG2956 146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLA--ELYLEQGDYEEAIAA-LERALEQDPDYLPALPRL-AEL 221

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 19114213 282 TSHEDELRRAEDYLSSINGLEKSSDLLLCKADTLFVRSRFIDVLAITTKILEID 335
Cdd:COG2956 222 YEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 516-549 8.09e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 8.09e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 19114213    516 AATWANLGHAYRKLKMYDAAIDALNQGLLLSTND 549
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_8 pfam13181
Tetratricopeptide repeat;
200-232 2.73e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.84  E-value: 2.73e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 19114213   200 ASMCYLRGQVYTNLSNFDRAKECYKEALMVDAK 232
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
 
Name Accession Description Interval E-value
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 96-176 1.18e-20

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 86.54  E-value: 1.18e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213    96 MQQQYKCAAFVGEKVL-DITGNPNDAFWLAQVYCCTGDYARAKCLLTKEDLYNRSSACRYLAAFCLVKLYDWQGALNLLG 174
Cdd:pfam12895   1 DQHQYKNAIFLAERLLaAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLGCRYLFAQCLLKLKKYDEALDALG 80


                  ..
gi 19114213   175 ET 176
Cdd:pfam12895  81 KA 82
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 330-578 5.08e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.48  E-value: 5.08e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 330 KILEIDPYNLDVYpLHLASLHES-GEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGP 408
Cdd:COG2956  33 EALELDPETVEAH-LALGNLYRRrGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 409 AWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNK 488
Cdd:COG2956 112 ALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 489 SDMQTAINHFQNALllvkktqSNEKPWAATWANLGHAYRKLKMYDAAIDALNQgLLLSTNDANVHTAIALVYLHKKIPGL 568
Cdd:COG2956 192 GDYEEAIAALERAL-------EQDPDYLPALPRLAELYEKLGDPEEALELLRK-ALELDPSDDLLLALADLLERKEGLEA 263

                       250
                ....*....|
gi 19114213 569 AITHLHESLA 578
Cdd:COG2956 264 ALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 373-596 4.25e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 82.08  E-value: 4.25e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 373 AVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHM 452
Cdd:COG2956   8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 453 QLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALLLVKKTqsnekpwAATWANLGHAYRKLKMY 532
Cdd:COG2956  88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN-------AHAYCELAELYLEQGDY 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19114213 533 DAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASDLLKRALEE 596
Cdd:COG2956 161 DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEK 224
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
402-597 1.89e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.28  E-value: 1.89e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 402 MDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNEL 481
Cdd:COG0457   3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 482 GVVAFNKSDMQTAINHFQNALLLvkktqSNEKPWAatWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYL 561
Cdd:COG0457  83 GLALQALGRYEEALEDYDKALEL-----DPDDAEA--LYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                       170       180       190
                ....*....|....*....|....*....|....*.
gi 19114213 562 HKKIPGLAITHLHESLAISPNEIMASDLLKRALEEN 597
Cdd:COG0457 156 KLGRYEEALELLEKLEAAALAALLAAALGEAALALA 191
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
366-561 2.97e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 2.97e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 366 VDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYL 445
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 446 FLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALLLvkktqsnEKPWAATWANLGHA 525
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL-------DPDDADALYNLGIA 153

                       170       180       190
                ....*....|....*....|....*....|....*.
gi 19114213 526 YRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYL 561
Cdd:COG0457 154 LEKLGRYEEALELLEKLEAAALAALLAAALGEAALA 189
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 406-597 7.23e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 75.54  E-value: 7.23e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 406 FGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVA 485
Cdd:COG2956   7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 486 FNKSDMQTAINHFQNALllvKKTQSNEKpwaaTWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKI 565
Cdd:COG2956  87 LKAGLLDRAEELLEKLL---ELDPDDAE----ALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD 159

                       170       180       190
                ....*....|....*....|....*....|..
gi 19114213 566 PGLAITHLHESLAISPNEIMASDLLKRALEEN 597
Cdd:COG2956 160 YDEAIEALEKALKLDPDCARALLLLAELYLEQ 191
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 205-582 1.11e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 71.27  E-value: 1.11e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   205 LRGQVYTNLSNFDRAKECYKEALMVDAKCYEAFDQLvsnhlltadeewdlvLKLNYSTySKEDAAFLRSLYMLKLNKTSh 284
Cdd:TIGR02917 470 LLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANL---------------ARIDIQE-GNPDDAIQRFEKVLTIDPKN- 532

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   285 edelrraedyLSSINGLeksSDLLLCKADTLfvrsrfiDVLAITTKILEIDPYNLDVYPLHLASLHESGEKNKLYLISND 364
Cdd:TIGR02917 533 ----------LRAILAL---AGLYLRTGNEE-------EAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNE 592

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   365 LVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGthlpy 444
Cdd:TIGR02917 593 AADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPD----- 667

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   445 lFLGMQHMQlGNILLANEYLQSSYALFQY-------DPLLLNELGVVAFNKSDMQTAINHFQNALllvkKTQSNekpwAA 517
Cdd:TIGR02917 668 -NTEAQIGL-AQLLLAAKRTESAKKIAKSlqkqhpkAALGFELEGDLYLRQKDYPAAIQAYRKAL----KRAPS----SQ 737

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19114213   518 TWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPN 582
Cdd:TIGR02917 738 NAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 447-583 2.76e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.44  E-value: 2.76e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 447 LGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALLLvkktQSNEkpwAATWANLGHAY 526
Cdd:COG4783  10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL----DPDE---PEARLNLGLAL 82

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 19114213 527 RKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNE 583
Cdd:COG4783  83 LKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 450-594 3.17e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 69.64  E-value: 3.17e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 450 QHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALLLvkktqsneKP-WAATWANLGHAYRK 528
Cdd:COG3914  87 LLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPdFAEAYLNLGEALRR 158

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19114213 529 LKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASDLLKRAL 594
Cdd:COG3914 159 LGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL 224
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
332-569 2.68e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 64.26  E-value: 2.68e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 332 LEIDPYNLDVYpLHLASLHESGEKN----KLYlisNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFG 407
Cdd:COG0457   1 LELDPDDAEAY-NNLGLAYRRLGRYeeaiEDY---EKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 408 PAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFN 487
Cdd:COG0457  77 EALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEK 156

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 488 KSDMQTAINHFQNALLLVKKTQSNEKPWAATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPG 567
Cdd:COG0457 157 LGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLA 236


                ..
gi 19114213 568 LA 569
Cdd:COG0457 237 AL 238
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 204-502 4.99e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 4.99e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 204 YLRGQVYTNLSNFDRAKECYKEALMVDAKCYEAFDQLVSnhLLTADEEWDLVLKLnystyskedaafLRSLymLKLNKTS 283
Cdd:COG2956  12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGN--LYRRRGEYDRAIRI------------HQKL--LERDPDR 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 284 HEDELRRAEDYLSSINgLEKSSDLLLckadtlfvrsrfidvlaittKILEIDPYNLDVYpLHLASLHE-SGEKNKLYLIS 362
Cdd:COG2956  76 AEALLELAQDYLKAGL-LDRAEELLE--------------------KLLELDPDDAEAL-RLLAEIYEqEGDWEKAIEVL 133

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 363 NDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHL 442
Cdd:COG2956 134 ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLP 213

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 443 PYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNeLGVVAFNKSDMQTAINHFQNAL 502
Cdd:COG2956 214 ALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLERKEGLEAALALLERQL 272
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 116-590 9.69e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.02  E-value: 9.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   116 NPNDA---FWLAQVYCCTGDYARAKCLLTK-EDLYNRSSACRYLAAFCLVKLYDWQGALNLLGETnpfrkdeknanKLLM 191
Cdd:TIGR02917  52 DPNDAearFLLGKIYLALGDYAAAEKELRKaLSLGYPKNQVLPLLARAYLLQGKFQQVLDELPGK-----------TLLD 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   192 QDGGIKLEAsmcyLRGQVYTNLSNFDRAKECYKEALMVDAKcyeafdqlvsnhlltadeewdlvlklnySTYSKEDAAFL 271
Cdd:TIGR02917 121 DEGAAELLA----LRGLAYLGLGQLELAQKSYEQALAIDPR----------------------------SLYAKLGLAQL 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   272 rslymlKLNktshEDELRRAEDYLSSINGLE-KSSDLLLCKADTLFVRSRFIDVLAITTKILEIDPYNLDVYpLHLASLh 350
Cdd:TIGR02917 169 ------ALA----ENRFDEARALIDEVLTADpGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVL-LALATI- 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   351 esgeknklyLISNDLVDRHPEKAVTWLAVgiyylcVNKISEARRYfsksstmdpqfgPAWIGFAhsfaiEGEHDQAISAY 430
Cdd:TIGR02917 237 ---------LIEAGEFEEAEKHADALLKK------APNSPLAHYL------------KALVDFQ-----KKNYEDARETL 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   431 TTAARlFQGTHLPYLFL-GMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALllvKKTQ 509
Cdd:TIGR02917 285 QDALK-SAPEYLPALLLaGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPAL---GLDP 360

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   510 SNekpwAATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASDL 589
Cdd:TIGR02917 361 DD----PAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLL 436


                  .
gi 19114213   590 L 590
Cdd:TIGR02917 437 L 437
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 205-597 1.55e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 61.25  E-value: 1.55e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   205 LRGQVYTNLSNFDRAKECYKEALMVDAKCYEAFDQLVS-----NHLLTADEEWDLVLKlnySTYSKEDAAFLRSlyMLKL 279
Cdd:TIGR02917 198 LKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATilieaGEFEEAEKHADALLK---KAPNSPLAHYLKA--LVDF 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   280 NKTSHEDELRRAEDYLSSINGLEKSsdLLLCKAdTLFVRSRFIDVLAITTKILEIDPYNLDVYPLHLASLHESGEKNKLY 359
Cdd:TIGR02917 273 QKKNYEDARETLQDALKSAPEYLPA--LLLAGA-SEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAI 349

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   360 LISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARL-FQ 438
Cdd:TIGR02917 350 ATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLdPE 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   439 GTHLPyLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALllvkKTQSNEKPWAAT 518
Cdd:TIGR02917 430 LGRAD-LLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKAL----SIEPDFFPAAAN 504

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19114213   519 WANLGhayRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASDLLKRALEEN 597
Cdd:TIGR02917 505 LARID---IQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGK 580
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 371-504 4.29e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.20  E-value: 4.29e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 371 EKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQ 450
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 19114213 451 HMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALLL 504
Cdd:COG4783  82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 412-562 9.26e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 9.26e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 412 GFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDM 491
Cdd:COG3914  83 LAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRL 162

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19114213 492 QTAINHFQNALLLvkktqsneKP-WAATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLH 562
Cdd:COG3914 163 EEAIAALRRALEL--------DPdNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQ 226
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 516-597 1.37e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.86  E-value: 1.37e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 516 AATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASDLLKRALE 595
Cdd:COG4235  17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96


                ..
gi 19114213 596 EN 597
Cdd:COG4235  97 QQ 98
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 478-596 2.92e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.89  E-value: 2.92e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 478 LNELGVVAFNKSDMQTAINHFQNALLLvkktqSNEKPWAatWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIA 557
Cdd:COG4783   7 LYALAQALLLAGDYDEAEALLEKALEL-----DPDNPEA--FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLG 79

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 19114213 558 LVYLHKKIPGLAITHLHESLAISPNEIMASDLLKRALEE 596
Cdd:COG4783  80 LALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRA 118
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 266-470 5.22e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 5.22e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 266 EDAAFLRSLYMLKLNKTSHEDELRRAEDYLSSINGLEKSSDLLLCKADTLFVRSRFIDVLAIttkILEIDPYNLDVYPLH 345
Cdd:COG3914   8 ALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAA---AAAALLLLAALLELA 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 346 LASLHESGEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQ 425
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 19114213 426 AISAYTTAARLfQGTHLPYLF-LGMQHMQLGNILLANEYLQSSYAL 470
Cdd:COG3914 165 AIAALRRALEL-DPDNAEALNnLGNALQDLGRLEEAIAAYRRALEL 209
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
318-475 5.25e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.15  E-value: 5.25e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 318 RSRFIDVLAITTKILEIDPYNLDVYPLHLASLHESGEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFS 397
Cdd:COG4785  18 AASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFD 97

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19114213 398 KSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDP 475
Cdd:COG4785  98 QALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDP 175
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 403-502 2.20e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.39  E-value: 2.20e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 403 DPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELG 482
Cdd:COG4235  13 NPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92

                        90       100
                ....*....|....*....|
gi 19114213 483 VVAFNKSDMQTAINHFQNAL 502
Cdd:COG4235  93 LAAFQQGDYAEAIAAWQKLL 112
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
414-582 7.47e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 50.68  E-value: 7.47e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 414 AHSFAIEGEHDQAISAYTTAARLF----QGTHLPYLFLGMQHMQ--LGNILLANEYLQSSYALFQYDP---LLLNELGVV 484
Cdd:COG4785   3 ALALALLLALALAAAAASKAAILLaallFAAVLALAIALADLALalAAAALAAAALAAERIDRALALPdlaQLYYERGVA 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 485 AFNKSDMQTAINHFQNALLLVKKTqsnekpwAATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKK 564
Cdd:COG4785  83 YDSLGDYDLAIADFDQALELDPDL-------AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                       170
                ....*....|....*...
gi 19114213 565 IPGLAITHLHESLAISPN 582
Cdd:COG4785 156 RYELAIADLEKALELDPN 173
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 347-470 1.28e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.26  E-value: 1.28e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 347 ASLHESGEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQA 426
Cdd:COG4783  12 QALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEA 91

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 19114213 427 ISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYAL 470
Cdd:COG4783  92 LALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 366-465 2.07e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 2.07e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 366 VDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYL 445
Cdd:COG4235  10 LAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALY 89

                        90       100
                ....*....|....*....|
gi 19114213 446 FLGMQHMQLGNILLANEYLQ 465
Cdd:COG4235  90 LLGLAAFQQGDYAEAIAAWQ 109
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 422-581 2.22e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.03  E-value: 2.22e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 422 EHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNA 501
Cdd:COG5010   1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 502 LLLvkktqsnEKPWAATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISP 581
Cdd:COG5010  81 LQL-------DPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR_12 pfam13424
Tetratricopeptide repeat;
477-543 2.59e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.46  E-value: 2.59e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19114213   477 LLNELGVVAFNKSDMQTAINHFQNALLLVKKTQSNEKPWAATWA-NLGHAYRKLKMYDAAIDALNQGL 543
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLlNLGRLYLELGRYEEALELLERAL 72
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 215-582 2.85e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 2.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   215 NFDRAKECYKEALMVDAKCYEAFDQLVSNHLLTADEEWDLVLklnYSTYSKEDA-----AFLRSLYMLKLNktshedELR 289
Cdd:TIGR02917 514 NPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAW---LEKAAELNPqeiepALALAQYYLGKG------QLK 584

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   290 RAEDYLSSINGLEKSS-DLLLCKADTLFVRSRFIDVLAITTKILEIDPYNLDVYpLHLASLHESGEKNK---LYLISNdl 365
Cdd:TIGR02917 585 KALAILNEAADAAPDSpEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALAL-LLLADAYAVMKNYAkaiTSLKRA-- 661

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   366 VDRHPEKAVTWLAVGIYYLCVNKISEAR---RYFSKSSTMDPqFGPAWIGFAHsfAIEGEHDQAISAYTTAARLfQGTHL 442
Cdd:TIGR02917 662 LELKPDNTEAQIGLAQLLLAAKRTESAKkiaKSLQKQHPKAA-LGFELEGDLY--LRQKDYPAAIQAYRKALKR-APSSQ 737

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   443 PYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNallLVKKTQSNekpwAATWANL 522
Cdd:TIGR02917 738 NAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQT---VVKKAPDN----AVVLNNL 810

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19114213   523 GHAYRKLKmyDA-AIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPN 582
Cdd:TIGR02917 811 AWLYLELK--DPrALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPE 869
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 387-597 6.15e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 6.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   387 NKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQS 466
Cdd:TIGR02917 173 NRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADA 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   467 SYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALllvkkTQSNEKPWAATWAnlGHAYRKLKMYDAAIDALNQGLLLS 546
Cdd:TIGR02917 253 LLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDAL-----KSAPEYLPALLLA--GASEYQLGNLEQAYQYLNQILKYA 325

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 19114213   547 TNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASDLLKRALEEN 597
Cdd:TIGR02917 326 PNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLAL 376
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 123-335 6.16e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.57  E-value: 6.16e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 123 LAQVYCCTGDYARAKCLLTK-EDLYNRSSACRYLAAFCLVKLYDWQGALNLLgetnpfrkdeknaNKLLMQDGGiklEAS 201
Cdd:COG2956  82 LAQDYLKAGLLDRAEELLEKlLELDPDDAEALRLLAEIYEQEGDWEKAIEVL-------------ERLLKLGPE---NAH 145

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 202 MCYLRGQVYTNLSNFDRAKECYKEALMVDAKCYEAFDQLVsnHLLTADEEWDLVLKLnYSTYSKEDAAFLRSLYMLkLNK 281
Cdd:COG2956 146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLA--ELYLEQGDYEEAIAA-LERALEQDPDYLPALPRL-AEL 221

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 19114213 282 TSHEDELRRAEDYLSSINGLEKSSDLLLCKADTLFVRSRFIDVLAITTKILEID 335
Cdd:COG2956 222 YEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 421-504 6.22e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.88  E-value: 6.22e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 421 GEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQN 500
Cdd:COG5010  68 GDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147


                ....
gi 19114213 501 ALLL 504
Cdd:COG5010 148 ALGT 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
342-578 9.90e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.22  E-value: 9.90e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 342 YPLHLASLHESGEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLC------VNKISEARRYFSKSSTMDPQFGPAWIGFAH 415
Cdd:COG4785   2 YALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLAlalaaaALAAAALAAERIDRALALPDLAQLYYERGV 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 416 SFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAI 495
Cdd:COG4785  82 AYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAI 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 496 NHFQNALLLvkktqSNEKPWAATWANLghAYRKLKmYDAAIDALNQglllstndanvhtAIALVYLHKKIPGLAITHLHE 575
Cdd:COG4785 162 ADLEKALEL-----DPNDPERALWLYL--AERKLD-PEKALALLLE-------------DWATAYLLQGDTEEARELFKL 220


                ...
gi 19114213 576 SLA 578
Cdd:COG4785 221 ALA 223
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 320-470 1.32e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 1.32e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 320 RFIDVLAITTKILEIDPYNLDVYPLHLASLHESGEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKS 399
Cdd:COG5010   1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19114213 400 STMDPQFGPAWIGFAHSFAIEGEHDQAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYAL 470
Cdd:COG5010  81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
484-582 2.15e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 2.15e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 484 VAFNKSDMQTAINHFQNALLLVKKtqsnekpWAATWANLGHAYRKLKMYDAAIdALNQGLLLSTNDANVHTAIALVYLHK 563
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPD-------NADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLEL 72

                        90
                ....*....|....*....
gi 19114213 564 KIPGLAITHLHESLAISPN 582
Cdd:COG3063  73 GDYDEALAYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 516-590 3.77e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 3.77e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19114213 516 AATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASDLL 590
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNL 78
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
382-470 5.33e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 5.33e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 382 YYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAIsAYTTAARLFQGTHLPYLFLGMQHMQLGNILLAN 461
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                ....*....
gi 19114213 462 EYLQSSYAL 470
Cdd:COG3063  80 AYLERALEL 88
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 515-597 8.20e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 8.20e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 515 WAATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASDLLKRAL 594
Cdd:COG5010  53 AFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALL 132


                ...
gi 19114213 595 EEN 597
Cdd:COG5010 133 LSL 135
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 425-551 1.21e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 42.30  E-value: 1.21e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 425 QAISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINHFQNALll 504
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL-- 78

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 19114213 505 vkKTQSNEkpwAATWANLGHAYRKLKMYDAAIDALNQglLLSTNDAN 551
Cdd:COG4235  79 --ALDPDN---PEALYLLGLAAFQQGDYAEAIAAWQK--LLALLPAD 118
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 268-479 1.72e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.60  E-value: 1.72e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 268 AAFLRSLYMLKLNKTSHEDELRRAEDYLSSINGLEKSSDLLLCKADTLFVRS-RFIDVLAITTKILEIDPYNLDVYPLHL 346
Cdd:COG3914  40 ALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALgRYEEALALYRRALALNPDNAEALFNLG 119

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 347 ASLHESGEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQA 426
Cdd:COG3914 120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 19114213 427 ISAYTTAARLFQGTHLPYLFLGMQHMQLGNILLANEYLQSSYALFQYDPLLLN 479
Cdd:COG3914 200 IAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSP 252
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 352-609 2.10e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 2.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   352 SGEKNKLYLISNDLVDRHPEKAVTWLAVGIYYLCVNKISEARRYFSKSSTMDPQFGPAWIGFAHSFAIEGEHDQAISAYT 431
Cdd:TIGR02917 444 SGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFE 523

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   432 TAARLFQgTHLPYLfLGMQHMQL--GNILLANEYLQSSYALfqyDPLLLN-ELGVVAFNKSDMQTAinhfqNALLLVKKT 508
Cdd:TIGR02917 524 KVLTIDP-KNLRAI-LALAGLYLrtGNEEEAVAWLEKAAEL---NPQEIEpALALAQYYLGKGQLK-----KALAILNEA 593

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213   509 QSNEKPWAATWANLGHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAITHLHESLAISPNEIMASD 588
Cdd:TIGR02917 594 ADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQI 673

                         250       260
                  ....*....|....*....|..
gi 19114213   589 LLKR-ALEENSLTSGFLNSKYV 609
Cdd:TIGR02917 674 GLAQlLLAAKRTESAKKIAKSL 695
TPR_1 pfam00515
Tetratricopeptide repeat;
516-545 4.31e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.17  E-value: 4.31e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 19114213   516 AATWANLGHAYRKLKMYDAAIDALNQGLLL 545
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALEL 30
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 516-549 8.09e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 8.09e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 19114213    516 AATWANLGHAYRKLKMYDAAIDALNQGLLLSTND 549
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
451-546 2.01e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 2.01e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114213 451 HMQLGNILLANEYLQSSYALFQYDPLLLNELGVVAFNKSDMQTAINhFQNALLLvkktqsnEKPWAATWANLGHAYRKLK 530
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKL-------DPNNAEALLNLAELLLELG 73

                        90
                ....*....|....*.
gi 19114213 531 MYDAAIDALNQGLLLS 546
Cdd:COG3063  74 DYDEALAYLERALELD 89
TPR_8 pfam13181
Tetratricopeptide repeat;
200-232 2.73e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.84  E-value: 2.73e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 19114213   200 ASMCYLRGQVYTNLSNFDRAKECYKEALMVDAK 232
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_1 pfam00515
Tetratricopeptide repeat;
200-230 3.71e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 3.71e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 19114213   200 ASMCYLRGQVYTNLSNFDRAKECYKEALMVD 230
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELN 31
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
525-596 7.97e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.30  E-value: 7.97e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19114213 525 AYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYLHKKIPGLAIThLHESLAISPNEIMASDLLKRALEE 596
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLE 71
TPR_11 pfam13414
TPR repeat;
523-561 9.20e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 34.37  E-value: 9.20e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 19114213   523 GHAYRKLKMYDAAIDALNQGLLLSTNDANVHTAIALVYL 561
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYY 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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