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Conserved domains on  [gi|19115413|ref|NP_594501|]
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L-azetidine-2-carboxylic acid acetyltransferase Aca1 [Schizosaccharomyces pombe]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11441181)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
100-199 7.82e-12

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


:

Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 60.78  E-value: 7.82e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115413 100 LGAFYIKPNYPgrcsHICNGGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSsVFNLVFATNIKSIRLWERLNFTRAGII 179
Cdd:COG1247  69 LGPFRPRPAYR----GTAEESIYVDPDARGRGIGRALLEALIERARARGYRR-LVAVVLADNEASIALYEKLGFEEVGTL 143

                        90       100
                ....*....|....*....|
gi 19115413 180 KDAGRLKGHegYVDAYIYQY 199
Cdd:COG1247 144 PEVGFKFGR--WLDLVLMQK 161
 
Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
100-199 7.82e-12

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 60.78  E-value: 7.82e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115413 100 LGAFYIKPNYPgrcsHICNGGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSsVFNLVFATNIKSIRLWERLNFTRAGII 179
Cdd:COG1247  69 LGPFRPRPAYR----GTAEESIYVDPDARGRGIGRALLEALIERARARGYRR-LVAVVLADNEASIALYEKLGFEEVGTL 143

                        90       100
                ....*....|....*....|
gi 19115413 180 KDAGRLKGHegYVDAYIYQY 199
Cdd:COG1247 144 PEVGFKFGR--WLDLVLMQK 161
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 56-173 4.97e-09

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 52.13  E-value: 4.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115413    56 IKMTRNEAEDFFFKFCTVICVPVESETSPAPDLATASIDWKTSLLGAFYIKPNY-PGRCSHICngGFLVSPSHRSKGIGR 134
Cdd:pfam00583   1 LEALYELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDdEPPVGEIE--GLAVAPEYRGKGIGT 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 19115413   135 NLANAYLYFAPRIGFKsSVFNLVFATNIKSIRLWERLNF 173
Cdd:pfam00583  79 ALLQALLEWARERGCE-RIFLEVAADNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
100-199 7.82e-12

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 60.78  E-value: 7.82e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115413 100 LGAFYIKPNYPgrcsHICNGGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSsVFNLVFATNIKSIRLWERLNFTRAGII 179
Cdd:COG1247  69 LGPFRPRPAYR----GTAEESIYVDPDARGRGIGRALLEALIERARARGYRR-LVAVVLADNEASIALYEKLGFEEVGTL 143

                        90       100
                ....*....|....*....|
gi 19115413 180 KDAGRLKGHegYVDAYIYQY 199
Cdd:COG1247 144 PEVGFKFGR--WLDLVLMQK 161
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 104-197 1.89e-09

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 54.62  E-value: 1.89e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115413 104 YIKPNYPGRCSHIcngGFLVSPSHRSKGIGRNLANAYLYFA------PRIGFKssvfnlVFATNIKSIRLWERLNFTRAG 177
Cdd:COG1670  79 LYDIDRANRSAEI---GYWLAPAYWGKGYATEALRALLDYAfeelglHRVEAE------VDPDNTASIRVLEKLGFRLEG 149

                        90       100
                ....*....|....*....|
gi 19115413 178 IIKDAGRLKGHegYVDAYIY 197
Cdd:COG1670 150 TLRDALVIDGR--YRDHVLY 167
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 56-173 4.97e-09

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 52.13  E-value: 4.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115413    56 IKMTRNEAEDFFFKFCTVICVPVESETSPAPDLATASIDWKTSLLGAFYIKPNY-PGRCSHICngGFLVSPSHRSKGIGR 134
Cdd:pfam00583   1 LEALYELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDdEPPVGEIE--GLAVAPEYRGKGIGT 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 19115413   135 NLANAYLYFAPRIGFKsSVFNLVFATNIKSIRLWERLNF 173
Cdd:pfam00583  79 ALLQALLEWARERGCE-RIFLEVAADNLAAIALYEKLGF 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 101-181 1.80e-08

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 50.04  E-value: 1.80e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115413 101 GAFYIKPNYPGRCSHICNggFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSsVFNLVFATNIKSIRLWERLNFTRAGIIK 180
Cdd:COG0456   1 GFALLGLVDGGDEAEIED--LAVDPEYRGRGIGRALLEAALERARERGARR-LRLEVREDNEAAIALYEKLGFEEVGERP 77


                .
gi 19115413 181 D 181
Cdd:COG0456  78 N 78
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
119-177 4.66e-04

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 38.91  E-value: 4.66e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 19115413 119 GGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSsvfnLVFATNIKSIRLWERLNFTRAG 177
Cdd:COG3153  71 GPLAVDPEYRGQGIGRALMRAALEAARERGARA----VVLLGDPSLLPFYERFGFRPAG 125
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 123-177 1.34e-03

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 37.73  E-value: 1.34e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 19115413 123 VSPSHRSKGIGRNLANAYLYFAPRIGFKSSVFNlVFATNIKSIRLWERLNFTRAG 177
Cdd:COG0454  66 VLPEYRGKGIGKALLEALLEWARERGCTALELD-TLDGNPAAIRFYERLGFKEIE 119
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 111-175 1.74e-03

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 36.28  E-value: 1.74e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19115413   111 GRCSHICNGGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKssvfNLVFATNIKSIRLWERLNFTR 175
Cdd:pfam13508  24 DDEGALAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIK----LLELETTNRAAAFYEKLGFEE 84
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 123-177 2.34e-03

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 36.89  E-value: 2.34e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 19115413 123 VSPSHRSKGIGRNLANAYLYFAPRIGFKSsvfnLVFATNIKSIRLWERLNFTRAG 177
Cdd:COG1246  60 VHPDYRGRGIGRRLLEALLAEARELGLKR----LFLLTTSAAIHFYEKLGFEEID 110
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 119-174 3.30e-03

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 35.38  E-value: 3.30e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 19115413   119 GGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSSVfnLVFATNIKSIRLWERLNFT 174
Cdd:pfam08445  25 GALQTLPEHRRRGLGSRLVAALARGIAERGITPFA--VVVAGNTPSRRLYEKLGFR 78
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
119-177 7.14e-03

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 34.50  E-value: 7.14e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 19115413 119 GGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSSVFNlVFATNIKSIRLWERLNFTRAG 177
Cdd:COG3393  19 SGVYTHPEYRGRGLASALVAALAREALARGARTPFLY-VDADNPAARRLYERLGFRPVG 76
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 112-177 7.96e-03

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 35.32  E-value: 7.96e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19115413   112 RCSHICngGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSSVFNlVFATNiKSIRLWERLNFTRAG 177
Cdd:pfam13673  50 DRGHIS--LLFVDPDYQGQGIGKALLEAVEDYAEKDGIKLSELT-VNASP-YAVPFYEKLGFRATG 111
Acetyltransf_4 pfam13420
Acetyltransferase (GNAT) domain;
128-189 8.49e-03

Acetyltransferase (GNAT) domain;


Pssm-ID: 433192 [Multi-domain]  Cd Length: 153  Bit Score: 35.42  E-value: 8.49e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19115413   128 RSKGIGRNLANAYLYFAPRIGFKSSVFNLVFATNIKSIRLWERLNFTRAGIIKDAGRLKGHE 189
Cdd:pfam13420  87 NDEGINRELINAIIQYARKNQNIENLEACIASNNINAIVFLKAIGFEWLGIERNAIKKNGRW 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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