|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
19-337 |
6.86e-115 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 335.69 E-value: 6.86e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 19 IPWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHMLFYGSPGTGKTSTILALSRELFGpQLMKSRVLELNASDERGIS 98
Cdd:PRK00440 5 EIWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYG-EDWRENFLELNASDERGID 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 99 IIREKVKSFAKTTVTNKVdgypcpPFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSKYR 178
Cdd:PRK00440 84 VIRNKIKEFARTAPVGGA------PFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 179 FKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLhqGTPITISSVEELAGAVPYNIIRSLL 258
Cdd:PRK00440 158 FSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAAT--GKEVTEEAVYKITGTARPEEIREMI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 259 DTAYTKNVSNIETLSRDVAAE-GYSTGIILSQLHDVLLkEETLSSPVKYKIFMKLSEVDKRLNDGADETLQLLDLLSSIS 337
Cdd:PRK00440 236 ELALNGDFTEAREKLRDLMIDyGLSGEDIIKQIHREVW-SLDIPEELKVELIDAIGEADFRITEGANERIQLEALLAKLA 314
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
19-339 |
1.03e-70 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 222.68 E-value: 1.03e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 19 IPWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHMLFYGSPGTGKTSTILALSRELFGPQlMKSRVLELNASDERGIS 98
Cdd:PLN03025 1 LPWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGPN-YKEAVLELNASDDRGID 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 99 IIREKVKSFAKTTVTnkvdgypCPP--FKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSK 176
Cdd:PLN03025 80 VVRNKIKMFAQKKVT-------LPPgrHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 177 YRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAAN-------------LHQGTPITISsve 243
Cdd:PLN03025 153 VRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQATHSgfgfvnqenvfkvCDQPHPLHVK--- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 244 elagavpyNIIRSLLDTAYTKNVSNIETLSrdvaAEGYSTGIILSQLHDVlLKEETLSSPVKYKIFMKLSEVDKRLNDGA 323
Cdd:PLN03025 230 --------NIVRNCLKGKFDDACDGLKQLY----DLGYSPTDIITTLFRV-VKNYDMPEFLKLEYLREIGFAHMRICDGV 296
|
330
....*....|....*.
gi 19115452 324 DETLQLLDLLSSISVV 339
Cdd:PLN03025 297 GSLLQLSGLLAKLCLV 312
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
21-337 |
2.44e-65 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 209.46 E-value: 2.44e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 21 WVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHMLFYGSPGTGKTSTILALSRELFGpQLMKSRVLELNASD--ERG-- 96
Cdd:PRK12402 5 WTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYG-DPWENNFTEFNVADffDQGkk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 97 ----------------------ISIIREKVKSFAKTTvtnKVDGypcpPFKIIILDEADSMTQDAQAALRRTMESYARIT 154
Cdd:PRK12402 84 ylvedprfahflgtdkrirsskIDNFKHVLKEYASYR---PLSA----DYKTILLDNAEALREDAQQALRRIMEQYSRTC 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 155 RFCLICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANlhQG 234
Cdd:PRK12402 157 RFIIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAAL--AA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 235 TPITISSVEELAGAVPY-NIIRSLLDTAYTKNV----SNIETLSRDvaaEGYSTGIILSQLHDVLLKEETLSSPVkyKIF 309
Cdd:PRK12402 235 GEITMEAAYEALGDVGTdEVIESLLDAAEAGDFtdarKTLDDLLID---EGLSGGEVLEELLRVARSRYRGDNLA--RLH 309
|
330 340
....*....|....*....|....*...
gi 19115452 310 MKLSEVDKRLNDGADETLQLLDLLSSIS 337
Cdd:PRK12402 310 RLAADADARLTDGANDRIQLEALLAELG 337
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
66-339 |
5.03e-57 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 198.14 E-value: 5.03e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 66 TSTILALSRELFGPQlMKSRVLELNASDERGISIIREKVKSFAKTTVTNKVdgypcpPFKIIILDEADSMTQDAQAALRR 145
Cdd:PRK04132 580 TTAALALARELFGEN-WRHNFLELNASDERGINVIREKVKEFARTKPIGGA------SFKIIFLDEADALTQDAQQALRR 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 146 TMESYARITRFCLICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFL 225
Cdd:PRK04132 653 TMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINIL 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 226 QSAANLhqGTPITISSVEELAGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAE-GYSTGIILSQLHDVLLKEEtLSSPV 304
Cdd:PRK04132 733 QAAAAL--DDKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKqGLSGEDVLVQMHREVFNLP-IDEPK 809
|
250 260 270
....*....|....*....|....*....|....*
gi 19115452 305 KYKIFMKLSEVDKRLNDGADETLQLLDLLSSISVV 339
Cdd:PRK04132 810 KVELADKIGEYNFRLVEGANEMIQLEALLAQFTLM 844
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
36-337 |
1.35e-53 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 177.86 E-value: 1.35e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 36 QESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTSTILALSRELFG-------------PQLMKSR----VLELNA---SDE 94
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLCenpeggkacgqchSRLMAAGnhpdLLELNPeekSDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 95 RGISIIREKVKSFAKTTVTNkvdgypcpPFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRC 174
Cdd:COG0470 81 IGIDQIRELGEFLSLTPLEG--------GRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRC 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 175 SKYRFKPLDNENMVKRLEfiaaDQAVsmEPGVVNALVECSGGDMRKAITFLQSAAnlhQGTPItissVEELAGAVPYNII 254
Cdd:COG0470 153 QVIRFRPPSEEEALAWLR----EEGV--DEDALEAILRLAGGDPRAAINLLQALA---GRKEL----LEDLAALLSRDRA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 255 RSLLDtaytknvsnieTLSRDVAAEGYSTgiILSQLHDVLLKEetLSSPVKYKIFMKLSEVDKRLNDGADETLQLLDLLS 334
Cdd:COG0470 220 LELLD-----------ALLKAEALELLDW--LLKWLLDNLPLE--YAGEDLARAYEALSEADRRLGRYANDRLLLEALLA 284
|
...
gi 19115452 335 SIS 337
Cdd:COG0470 285 KLG 287
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
21-229 |
4.05e-37 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 135.50 E-value: 4.05e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 21 WVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHMLFY-GSPGTGKTSTILALSRElfgpqlMKSRVLELNASDERgISI 99
Cdd:PHA02544 11 WEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHsPSPGTGKTTVAKALCNE------VGAEVLFVNGSDCR-IDF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 100 IREKVKSFAkTTVTNKvdgypcPPFKIIILDEAD-SMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSKYR 178
Cdd:PHA02544 84 VRNRLTRFA-STVSLT------GGGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVID 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 19115452 179 FKPLDNEN-------MVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAA 229
Cdd:PHA02544 157 FGVPTKEEqiemmkqMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQRYA 214
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
19-276 |
2.05e-34 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 131.58 E-value: 2.05e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 19 IPWVELYRPKTLDQVSSQESTVQVLKKTLLS--NNLPH--MLFYGSPGTGKTSTILALSRElfgpqlMKSRVLELNASDE 94
Cdd:PRK04195 2 MPWVEKYRPKTLSDVVGNEKAKEQLREWIESwlKGKPKkaLLLYGPPGVGKTSLAHALAND------YGWEVIELNASDQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 95 RGISIIREKVKSFAKT-TVTNKvdgypcpPFKIIILDEADSM--TQD---AQAALRRTMESYARITrfcLICN--YMTRi 166
Cdd:PRK04195 76 RTADVIERVAGEAATSgSLFGA-------RRKLILLDEVDGIhgNEDrggARAILELIKKAKQPII---LTANdpYDPS- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 167 IDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANlhQGTPITISSVEELA 246
Cdd:PRK04195 145 LRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIAE--GYGKLTLEDVKTLG 222
|
250 260 270
....*....|....*....|....*....|.
gi 19115452 247 G-AVPYNIIRSLLDTAYTKNVSNIETLSRDV 276
Cdd:PRK04195 223 RrDREESIFDALDAVFKARNADQALEASYDV 253
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
19-333 |
9.46e-32 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 124.17 E-value: 9.46e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 19 IPWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTST--ILALSRELFGPQLMKS----------- 84
Cdd:PRK14953 4 IPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAyIFAGPRGTGKTTIarILAKVLNCLNPQEGEPcgkcencveid 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 85 -----RVLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLI 159
Cdd:PRK14953 84 kgsfpDLIEIDAASNRGIDDIRALRDAVSYTPIKGK--------YKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILC 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 160 CNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITI 239
Cdd:PRK14953 156 TTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGK-VTI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 240 SSVEELAGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQLHDVLLKEetlsspVKYKIFMKLSEVDKRL 319
Cdd:PRK14953 235 KVVEEFLGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNI------LLNKSLKNPEEVFQVE 308
|
330
....*....|....
gi 19115452 320 NDGADETLQLLDLL 333
Cdd:PRK14953 309 DFYRKLEKPLEALL 322
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
27-334 |
1.68e-26 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 107.20 E-value: 1.68e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 27 PKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTST--ILA-----LSRELFGP--------QLMKSR---VL 87
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLarILAkalncENGPTGEPcgecescrAIAAGShpdVI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 88 EL--NASdERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTME---SYariTRFCLICNY 162
Cdd:COG2812 86 EIdaEAS-NIGVDDIRELIEKVSYAPVEGR--------YKVYIIDEAHMLTTEAFNALLKTLEeppPH---VVFILATTE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 163 MTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLhqgtpitissv 242
Cdd:COG2812 154 PQKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAF----------- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 243 eelaGAVPY-NIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQL----HDVLL-----KEETLSSPVKYKIFMKL 312
Cdd:COG2812 223 ----GLLDRrELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLlsllRDLLLlklgpDAELLVNEDERERLQEL 298
|
330 340
....*....|....*....|..
gi 19115452 313 SevdKRLndGADETLQLLDLLS 334
Cdd:COG2812 299 A---RRL--SPERLLRAIQILL 315
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
16-297 |
3.83e-26 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 109.14 E-value: 3.83e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 16 KKSIPWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTST--ILAL------SRELFGP------Q 80
Cdd:PRK07133 3 MKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHaYLFSGPRGTGKTSVakIFANalncshKTDLLEPcqecieN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 81 LMKS-RVLELNASDERGISIIREkvksfakttVTNKVDGYPC-PPFKIIILDEADSMTQDAQAALRRTMESYARITRFCL 158
Cdd:PRK07133 83 VNNSlDIIEMDAASNNGVDEIRE---------LIENVKNLPTqSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFIL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 159 ICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpIT 238
Cdd:PRK07133 154 ATTEVHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNK-IT 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 19115452 239 ISSVEELAGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQLHDvLLKE 297
Cdd:PRK07133 233 LKNVEELFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLIN-LVKE 290
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
25-297 |
4.81e-25 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 105.23 E-value: 4.81e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTST--ILALSRELFGPQLMKS----------------R 85
Cdd:PRK14962 8 YRPKTFSEVVGQDHVKKLIINALKKNSISHaYIFAGPRGTGKTTVarILAKSLNCENRKGVEPcnecracrsidegtfmD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTR 165
Cdd:PRK14962 88 VIELDAASNRGIDEIRKIRDAVGYRPMEGK--------YKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 166 IIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITISSVEEL 245
Cdd:PRK14962 160 VPPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGK-ITLETVHEA 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 19115452 246 AGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQLHDVLLKE 297
Cdd:PRK14962 239 LGLIPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAIEDLVED 290
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
23-247 |
1.46e-24 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 102.86 E-value: 1.46e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 23 ELYRPKTLDQVSSQESTV---QVLKKTLLSNNLPHMLFYGSPGTGKTSTILALSRELfgpqlmKSRVLELNASDErGISI 99
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGAT------DAPFEALSAVTS-GVKD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 100 IREKVKSfAKttvTNKVDGYPCppfkIIILDEADSMTQDAQAALRRTMESYaRITrfcLIC----N-YMTrIIDPLSSRC 174
Cdd:PRK13342 77 LREVIEE-AR---QRRSAGRRT----ILFIDEIHRFNKAQQDALLPHVEDG-TIT---LIGatteNpSFE-VNPALLSRA 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19115452 175 SKYRFKPLDNENMVKRLEFIAAD---QAVSMEPGVVNALVECSGGDMRKAITFLQSAANLhqGTPITISSVEELAG 247
Cdd:PRK13342 144 QVFELKPLSEEDIEQLLKRALEDkerGLVELDDEALDALARLANGDARRALNLLELAALG--VDSITLELLEEALQ 217
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
25-333 |
4.39e-22 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 97.03 E-value: 4.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTILALSRELFGPQLMKSR------------------ 85
Cdd:PRK08451 8 YRPKHFDELIGQESVSKTLSLALDNNRLAHAyLFSGLRGSGKTSSARIFARALVCEQGPSSTpcdtciqcqsalenrhid 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIR---EKVK---SFAKttvtnkvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLI 159
Cdd:PRK08451 88 IIEMDAASNRGIDDIReliEQTKykpSMAR--------------FKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 160 CNymtriiDPLS------SRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQ 233
Cdd:PRK08451 154 TT------DPLKlpatilSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCK 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 234 GTpITISSVEELAGAVPYNIIRSLLDTAYTKNVSNIETLSRDVaaEGYSTGIILSQ----LHDVLLKEETLSSPVKYKIF 309
Cdd:PRK08451 228 NA-ITESKVADMLGLLDPSKLEDFFQAILNQDKEKLFELLKEL--EDYEAEMVLDEmmlfLKEKFLSKDSEFSILLYERF 304
|
330 340
....*....|....*....|....*
gi 19115452 310 MK-LSEVDKRLNDGADETLQLLDLL 333
Cdd:PRK08451 305 FRiLSSAKSLLKEGADDGFVLLLML 329
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
25-280 |
3.17e-21 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 94.49 E-value: 3.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTST--ILALSRELFGPQ--------------LMKSR-- 85
Cdd:PRK14950 10 WRSQTFAELVGQEHVVQTLRNAIAEGRVAHAyLFTGPRGVGKTSTarILAKAVNCTTNDpkgrpcgtcemcraIAEGSav 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 -VLELNASDERGISIIREkvksfakttVTNKVDGYPCPP-FKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYM 163
Cdd:PRK14950 90 dVIEMDAASHTSVDDARE---------IIERVQFRPALArYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 164 TRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGtPITISSVE 243
Cdd:PRK14950 161 HKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGG-EISLSQVQ 239
|
250 260 270
....*....|....*....|....*....|....*..
gi 19115452 244 ELAGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEG 280
Cdd:PRK14950 240 SLLGISGDEEVKALAEALLAKDLKAALRTLNAVAADG 276
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
36-176 |
7.76e-21 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 87.20 E-value: 7.76e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 36 QESTVQVLKKTLLSNNLPHMLFYGSPGTGKTSTILALSRELFGPqlmKSRVLELNASDERGISIIREKVKSFAKTTVTNK 115
Cdd:cd00009 3 QEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRP---GAPFLYLNASDLLEGLVVAELFGHFLVRLLFEL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19115452 116 VdgyPCPPFKIIILDEADSMTQDAQAALRRTMESYARIT------RFCLICNYM--TRIIDPLSSRCSK 176
Cdd:cd00009 80 A---EKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLRidrenvRVIGATNRPllGDLDRALYDRLDI 145
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
26-257 |
1.55e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 92.21 E-value: 1.55e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 26 RPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTST--ILALSRELFGP-----------QLMKS----RVL 87
Cdd:PRK14963 9 RPITFDEVVGQEHVKEVLLAALRQGRLGHAyLFSGPRGVGKTTTarLIAMAVNCSGEdpkpcgecescLAVRRgahpDVL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 88 ELNASDERGISIIREkvksfakttVTNKVDGYPC-PPFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRI 166
Cdd:PRK14963 89 EIDAASNNSVEDVRD---------LREKVLLAPLrGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 167 IDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAanLHQGTPITISSVEELA 246
Cdd:PRK14963 160 PPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERL--LALGTPVTRKQVEEAL 237
|
250
....*....|.
gi 19115452 247 GAVPYNIIRSL 257
Cdd:PRK14963 238 GLPPQERLRGI 248
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
249-335 |
5.24e-19 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 80.21 E-value: 5.24e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 249 VPYNIIRSLLDTAYTKNVSNI-ETLSRDVAAEGYSTGIILSQLHDVLLKEEtLSSPVKYKIFMKLSEVDKRLNDGADETL 327
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAyKKVRELLVEKGYSLQDIITQLHRVVKSLD-LPEEVKLELLEKLGEIEYRLSEGASEKL 79
|
....*...
gi 19115452 328 QLLDLLSS 335
Cdd:pfam08542 80 QLSALLAA 87
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
26-251 |
2.23e-17 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 82.41 E-value: 2.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 26 RPKTLDQVSSQESTV---QVLKKTLLSNNLPHMLFYGSPGTGKTS--TILAlsrelfgpQLMKSRVLELNASDErGISII 100
Cdd:COG2256 20 RPRTLDEVVGQEHLLgpgKPLRRAIEAGRLSSMILWGPPGTGKTTlaRLIA--------NATDAEFVALSAVTS-GVKDI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 101 REKVKSfAKttvTNKVDGYPCppfkIIILDEADSMTQDAQAALRRTMESyARITrfcLIC----N-YMTrIIDPLSSRCS 175
Cdd:COG2256 91 REVIEE-AR---ERRAYGRRT----ILFVDEIHRFNKAQQDALLPHVED-GTIT---LIGatteNpSFE-VNSALLSRCR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 176 KYRFKPLDNENMVKRLEFIAAD-------QAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGT---PITISSVEEL 245
Cdd:COG2256 158 VFVLKPLSEEDLEQLLERALADderglggYKLELDDEALEALARLADGDARRALNALELAVLSAPPDgviEITLELVEEA 237
|
....*...
gi 19115452 246 AG--AVPY 251
Cdd:COG2256 238 LQrrALRY 245
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
25-295 |
3.95e-17 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 82.20 E-value: 3.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTS--TILALSRELFGP------------QLMKSR---- 85
Cdd:PRK05896 10 YRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSiaKIFAKAINCLNPkdgdccnscsvcESINTNqsvd 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTR 165
Cdd:PRK05896 90 IVELDAASNNGVDEIRNIIDNINYLPTTFK--------YKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 166 IIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANlHQGTPITISSVEEL 245
Cdd:PRK05896 162 IPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLST-FKNSEIDIEDINKT 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 19115452 246 AGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQLHDVLL 295
Cdd:PRK05896 241 FGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLI 290
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
25-280 |
8.96e-17 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 81.07 E-value: 8.96e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTST--ILA-----LSRELFGP-------------QLMK 83
Cdd:PRK05563 10 WRPQTFEDVVGQEHITKTLKNAIKQGKISHaYLFSGPRGTGKTSAakIFAkavncLNPPDGEPcneceickaitngSLMD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 84 srVLELNASDERG---ISIIREKVKsFAKTTVTNKVdgYpcppfkiiILDEADSMTQDAQAALRRTME---SYAR----- 152
Cdd:PRK05563 90 --VIEIDAASNNGvdeIRDIRDKVK-YAPSEAKYKV--Y--------IIDEVHMLSTGAFNALLKTLEeppAHVIfilat 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 153 -------ITrfclicnymtrIIdplsSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFL 225
Cdd:PRK05563 157 tephkipAT-----------IL----SRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSIL 221
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 19115452 226 QSAANLHQGTpITISSVEELAGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEG 280
Cdd:PRK05563 222 DQAISFGDGK-VTYEDALEVTGSVSQEALDDLVDAIVEGDVAKALKILEELLDEG 275
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
182-246 |
1.65e-15 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 69.87 E-value: 1.65e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19115452 182 LDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANlhQGTPITISSVEELA 246
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAA--GGGVITEEDVYEVA 63
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
19-268 |
3.28e-15 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 76.44 E-value: 3.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 19 IPWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTSTILALSRELFGPQLM--------------- 82
Cdd:PRK06645 9 IPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGgYLLTGIRGVGKTTSARIIAKAVNCSALItenttiktceqctnc 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 83 -------KSRVLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITR 155
Cdd:PRK06645 89 isfnnhnHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGK--------HKIFIIDEVHMLSKGAFNALLKTLEEPPPHII 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 156 FCLICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQ-- 233
Cdd:PRK06645 161 FIFATTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSAks 240
|
250 260 270
....*....|....*....|....*....|....*
gi 19115452 234 GTPITISSVEELAGAVPYNIIRSLLDTAYTKNVSN 268
Cdd:PRK06645 241 DNIISPQVINQMLGLVDSSVIIEFVEYIIHRETEK 275
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
20-290 |
4.18e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 76.26 E-value: 4.18e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 20 PWVELYRPKTLDQVSSQESTVQVLKKTLLSNNL-PHMLFYGSPGTGKTSTILALSREL---FGP---------------Q 80
Cdd:PRK14959 5 SLTARYRPQTFAEVAGQETVKAILSRAAQENRVaPAYLFSGTRGVGKTTIARIFAKALnceTAPtgepcntceqcrkvtQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 81 LMKSRVLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMES-YARITrFCLI 159
Cdd:PRK14959 85 GMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGR--------YKVFIIDEAHMLTREAFNALLKTLEEpPARVT-FVLA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 160 CNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLhQGTPITI 239
Cdd:PRK14959 156 TTEPHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLAL-GESRLTI 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 19115452 240 SSVEELAGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQL 290
Cdd:PRK14959 235 DGARGVLGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLREL 285
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
25-267 |
5.11e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 75.59 E-value: 5.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTST--ILALSRE-LFGP---------------QLMKSR 85
Cdd:PRK14964 7 YRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCarIISLCLNcSNGPtsdpcgtchncisikNSNHPD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTR 165
Cdd:PRK14964 87 VIEIDAASNTSVDDIKVILENSCYLPISSK--------FKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 166 IIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAAnLHQGTPITISSVEEL 245
Cdd:PRK14964 159 IPVTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAA-IYSNNKISEKSVRDL 237
|
250 260
....*....|....*....|..
gi 19115452 246 AGAVPYNIIRSLLDTAYTKNVS 267
Cdd:PRK14964 238 LGCVDKHILEDLVEAILLGDAQ 259
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
25-307 |
6.43e-15 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 75.19 E-value: 6.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTILALSRELFGPQLMKSR------------------ 85
Cdd:PRK06305 11 YRPQTFSEILGQDAVVAVLKNALRFNRAAHAyLFSGIRGTGKTTLARIFAKALNCQNPTEDQepcnqcasckeissgtsl 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 -VLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMT 164
Cdd:PRK06305 91 dVLEIDGASHRGIEDIRQINETVLFTPSKSR--------YKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIH 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 165 RIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITISSVEE 244
Cdd:PRK06305 163 KIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKS-LDPDSVAK 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 245 LAGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQL----HDVLLKEE---TLSSPVKYK 307
Cdd:PRK06305 242 ALGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLtlffRNILLKQYnkqLSSVATKYS 311
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
25-281 |
8.86e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 74.53 E-value: 8.86e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTSTILALSRELFGPQLMKS------RVLELNASDERGI 97
Cdd:PRK14970 11 YRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKINQPGYDDPnedfsfNIFELDAASNNSV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 98 SIIRekvksfakttvtNKVDGYPCPP----FKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSR 173
Cdd:PRK14970 91 DDIR------------NLIDQVRIPPqtgkYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 174 CSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLhQGTPITISSVEELAGAVPYNI 253
Cdd:PRK14970 159 CQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTF-CGKNITRQAVTENLNILDYDT 237
|
250 260
....*....|....*....|....*...
gi 19115452 254 IRSLLDTAYTKNVSNIETLSRDVAAEGY 281
Cdd:PRK14970 238 YINVTDLILENKIPELLLAFNEILRKGF 265
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
55-182 |
1.17e-14 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 69.93 E-value: 1.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 55 MLFYGSPGTGKTSTILALSRElfgpqlMKSRVLELNASDERGISII--REKVKSFAKTTVTNKvdgyPCppfkIIILDEA 132
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKE------LGAPFIEISGSELVSKYVGesEKRLRELFEAAKKLA----PC----VIFIDEI 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19115452 133 DSM-----------TQDAQAALRRTME---SYARITRFCLICNYMTRIIDPLSSRCSKYRFKPL 182
Cdd:pfam00004 67 DALagsrgsggdseSRRVVNQLLTELDgftSSNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
25-304 |
1.15e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 72.05 E-value: 1.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTILALSREL---------------FGPQLMKSR--- 85
Cdd:PRK08691 10 WRPKTFADLVGQEHVVKALQNALDEGRLHHAyLLTGTRGVGKTTIARILAKSLncenaqhgepcgvcqSCTQIDAGRyvd 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTR 165
Cdd:PRK08691 90 LLEIDAASNTGIDNIREVLENAQYAPTAGK--------YKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 166 IIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITISSVEEL 245
Cdd:PRK08691 162 VPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGK-VAENDVRQM 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 19115452 246 AGAVPYNIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQLHdVLLKEETLSSPV 304
Cdd:PRK08691 241 IGAVDKQYLYELLTGIINQDGAALLAKAQEMAACAVGFDNALGELA-ILLQQLALIQAV 298
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
25-249 |
2.25e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 70.93 E-value: 2.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTSTILALSRELFGPQLMKSR------------------ 85
Cdd:PRK14965 10 YRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTARILAKALNCEQGLTAEpcnvcppcveitegrsvd 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREKVKSfakttvtnkVDGYPCPP-FKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMT 164
Cdd:PRK14965 90 VFEIDGASNTGVDDIRELREN---------VKYLPSRSrYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 165 RIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVnALVECSG-GDMRKAITFL-QSAANLhqGTPITISSV 242
Cdd:PRK14965 161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAAL-ALVARKGdGSMRDSLSTLdQVLAFC--GDAVGDDDV 237
|
....*..
gi 19115452 243 EELAGAV 249
Cdd:PRK14965 238 AELLGVV 244
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
25-335 |
2.58e-13 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 70.85 E-value: 2.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTILALSRELFGPQLMKSRVLELNAS-----DERGIS 98
Cdd:PRK14960 9 YRPRNFNELVGQNHVSRALSSALERGRLHHAyLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATckavnEGRFID 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 99 IIREKVKSFAKTTVTNKV-DGYPCPP----FKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSR 173
Cdd:PRK14960 89 LIEIDAASRTKVEDTRELlDNVPYAPtqgrFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISR 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 174 CSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITISSVEELAGAVPYNI 253
Cdd:PRK14960 169 CLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGA-VHHQDVKEMLGLIDRTI 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 254 IRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQ----LHDVLLKEETLSSPVKYKifmklSEVDKRLndgadetLQL 329
Cdd:PRK14960 248 IYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQlistLHELALLQYLPELGLKYS-----EEINAKI-------LQL 315
|
....*.
gi 19115452 330 LDLLSS 335
Cdd:PRK14960 316 SKLISA 321
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
12-244 |
4.43e-13 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 70.08 E-value: 4.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 12 EQEAKKSIPWVELYRPKTLDQVSSQESTV---QVLKKTLLSNNLPHMLFYGSPGTGKTS--TILALSrelfgpqlMKSRV 86
Cdd:PRK13341 9 EQMSQSEAPLADRLRPRTLEEFVGQDHILgegRLLRRAIKADRVGSLILYGPPGVGKTTlaRIIANH--------TRAHF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 87 LELNASdERGISIIREKVKS-------FAKTTvtnkvdgypcppfkIIILDEADSMTQDAQAALRRTMESyARITrfcLI 159
Cdd:PRK13341 81 SSLNAV-LAGVKDLRAEVDRakerlerHGKRT--------------ILFIDEVHRFNKAQQDALLPWVEN-GTIT---LI 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 160 C----NYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQ-------AVSMEPGVVNALVECSGGDMRKAITFLQSA 228
Cdd:PRK13341 142 GatteNPYFEVNKALVSRSRLFRLKSLSDEDLHQLLKRALQDKergygdrKVDLEPEAEKHLVDVANGDARSLLNALELA 221
|
250 260
....*....|....*....|....
gi 19115452 229 anlHQGTP--------ITISSVEE 244
Cdd:PRK13341 222 ---VESTPpdedglidITLAIAEE 242
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
25-269 |
1.90e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 67.53 E-value: 1.90e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTILALSREL---FGPQLMKSRVLELNASDERGISII 100
Cdd:PRK14961 10 WRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTTIARLLAKSLncqNGITSNPCRKCIICKEIEKGLCLD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 101 REKVKSFAKTTVTNK---VDGYPCPP----FKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSR 173
Cdd:PRK14961 90 LIEIDAASRTKVEEMreiLDNIYYSPsksrFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 174 CSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITISSVEELAGAVPYNI 253
Cdd:PRK14961 170 CLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGN-INIKNVTDMLGLLNEKQ 248
|
250
....*....|....*.
gi 19115452 254 IRSLLDTAYTKNVSNI 269
Cdd:PRK14961 249 SFLLTDALLKKDSKKT 264
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
25-294 |
2.01e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 67.82 E-value: 2.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKT--STILALSRELFGP------------------QLMK 83
Cdd:PRK14951 10 YRPRSFSEMVGQEHVVQALTNALTQQRLHHAyLFTGTRGVGKTtvSRILAKSLNCQGPdgqggitatpcgvcqacrDIDS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 84 SRVL---ELNASDERGIsiirEKVKSFAKTTVTNKVDGYpcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLIC 160
Cdd:PRK14951 90 GRFVdytELDAASNRGV----DEVQQLLEQAVYKPVQGR----FKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLAT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 161 NymtriiDP------LSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQG 234
Cdd:PRK14951 162 T------DPqkvpvtVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSG 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19115452 235 TpITISSVEELAGAVPYNIIRSLLDT-AYTKNVSNIETlSRDVAAEGYSTGIILSQLHDVL 294
Cdd:PRK14951 236 Q-LQEAAVRQMLGSVDRSHVFRLIDAlAQGDGRTVVET-ADELRLNGLSAASTLEEMAAVL 294
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
36-183 |
2.74e-12 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 63.77 E-value: 2.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 36 QESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTSTILALSRELFGPQLMKS----------RVLELN-------ASDERGI 97
Cdd:pfam13177 2 QPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFCEEPGDDlpcgqcrscrRIESGNhpdlviiEPEGQSI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 98 SI--IREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCS 175
Cdd:pfam13177 82 KIdqIRELQKEFSKSPYEGK--------KKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQ 153
|
....*...
gi 19115452 176 KYRFKPLD 183
Cdd:pfam13177 154 IIRFKPLS 161
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
25-250 |
6.92e-12 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 66.14 E-value: 6.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNL-PHMLFYGSPGTGKTST--ILA-----LSRElfGP--------QLMKS---- 84
Cdd:PRK14948 10 YRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSarILAkslncLNSD--KPtpepcgkcELCRAiaag 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 85 ---RVLELNASDERGISIIREKV-KS-FAKTTVTNKVdgYpcppfkiiILDEADSMTQDAQAALRRTMESYARITRFCLI 159
Cdd:PRK14948 88 nalDVIEIDAASNTGVDNIRELIeRAqFAPVQARWKV--Y--------VIDECHMLSTAAFNALLKTLEEPPPRVVFVLA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 160 CNYMTRIIDPLSSRCSKYRFK--PLDneNMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFL-QsaANLHQGtP 236
Cdd:PRK14948 158 TTDPQRVLPTIISRCQRFDFRriPLE--AMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLdQ--LSLLPG-P 232
|
250
....*....|....
gi 19115452 237 ITISSVEELAGAVP 250
Cdd:PRK14948 233 ITPEAVWDLLGAVP 246
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
96-250 |
1.19e-11 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 65.06 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 96 GISI--IREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSR 173
Cdd:PRK09112 120 AITVdeIRRVGHFLSQTSGDGN--------WRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSR 191
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19115452 174 CSKYRFKPLDNENMVKRLEFIAADQAvsMEPGVVNALVECSGGDMRKAITFLQsaanlHQGTPItISSVEE-LAGAVP 250
Cdd:PRK09112 192 CQPISLKPLDDDELKKALSHLGSSQG--SDGEITEALLQRSKGSVRKALLLLN-----YGGLEI-IATIDQlLAGSGP 261
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
25-244 |
3.62e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 64.03 E-value: 3.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTS-------TILALSRELFGP-----------QLMKS- 84
Cdd:PRK14971 11 YRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTcarifakTINCQNLTADGEacnecescvafNEQRSy 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 85 RVLELNASDERGISIIRekvksfakttvtNKVDGYPCPP----FKIIILDEADSMTQDAQAALRRTMESYARITRFCLIC 160
Cdd:PRK14971 91 NIHELDAASNNSVDDIR------------NLIEQVRIPPqigkYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILAT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 161 NYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITIS 240
Cdd:PRK14971 159 TEKHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGN-ITYK 237
|
....
gi 19115452 241 SVEE 244
Cdd:PRK14971 238 SVIE 241
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
25-247 |
7.51e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 63.25 E-value: 7.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTILALSREL---FGPQLM--------KS-------R 85
Cdd:PRK06647 10 RRPRDFNSLEGQDFVVETLKHSIESNKIANAyIFSGPRGVGKTSSARAFARCLncvNGPTPMpcgecsscKSidndnslD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREkVKsfakttvtnkvDGYPCPP----FKIIILDEADSMTQDAQAALRRTMESYARITRFCLICN 161
Cdd:PRK06647 90 VIEIDGASNTSVQDVRQ-IK-----------EEIMFPPassrYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 162 YMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGtPITISS 241
Cdd:PRK06647 158 EVHKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDS-DITLEQ 236
|
....*.
gi 19115452 242 VEELAG 247
Cdd:PRK06647 237 IRSKMG 242
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
20-68 |
4.90e-10 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 60.62 E-value: 4.90e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 19115452 20 PWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHMLFYGSPGTGKTST 68
Cdd:PRK04132 8 PWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLT 56
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
25-259 |
1.16e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 59.50 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKT--STILALSRELFGPQL---MKSR------------- 85
Cdd:PRK12323 10 WRPRDFTTLVGQEHVVRALTHALEQQRLHHAyLFTGTRGVGKTtlSRILAKSLNCTGADGeggITAQpcgqcracteida 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 -----VLELNASDERGIsiirEKVKSFAKTTVTNKVDGYpcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLIC 160
Cdd:PRK12323 90 grfvdYIEMDAASNRGV----DEMAQLLDKAVYAPTAGR----FKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILAT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 161 NYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITIS 240
Cdd:PRK12323 162 TDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGN-VSEE 240
|
250
....*....|....*....
gi 19115452 241 SVEELAGAVPYNIIRSLLD 259
Cdd:PRK12323 241 AVRGMLGAIDQSYLVRLLD 259
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
25-259 |
2.37e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 58.22 E-value: 2.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTILALSRELFGPQLMKSR------------------ 85
Cdd:PRK14969 10 WRPKSFSELVGQEHVVRALTNALEQQRLHHAyLFTGTRGVGKTTLARILAKSLNCETGVTATpcgvcsacleidsgrfvd 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREKVKS--FAKTTVTnkvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYM 163
Cdd:PRK14969 90 LIEVDAASNTQVDAMRELLDNaqYAPTRGR----------FKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 164 TRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFL-QSAAnlHQGTPITISSV 242
Cdd:PRK14969 160 QKIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLdQAIA--YGGGTVNESEV 237
|
250
....*....|....*..
gi 19115452 243 EELAGAVPYNIIRSLLD 259
Cdd:PRK14969 238 RAMLGAIDQDYLFALLE 254
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
20-226 |
5.57e-09 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 57.27 E-value: 5.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 20 PWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPH-----MLFYGSPGTGKTSTILALSRELfGPQLMK----------- 83
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKEL-GIQVQEwsnptlpdfqk 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 84 -------------SRVLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppfKIIILDEADSMTQDAQAALRRTMES- 149
Cdd:TIGR00602 152 ndhkvtlslescfSNFQSQIEVFSEFLLRATNKLQMLGDDLMTDK---------KIILVEDLPNQFYRDTRALHEILRWk 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 150 YARITRFCLIC---------NYMTRIIDPLSS----------RCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVV--- 207
Cdd:TIGR00602 223 YVSIGRCPLVFiiteslegdNNQRRLLFPAETimnkeileepRVSNISFNPIAPTIMKKFLNRIVTIEAKKNGEKIKvpk 302
|
250 260
....*....|....*....|...
gi 19115452 208 NALVE--CSG--GDMRKAITFLQ 226
Cdd:TIGR00602 303 KTSVEllCQGcsGDIRSAINSLQ 325
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
25-259 |
8.77e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 56.78 E-value: 8.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTStilaLSReLFGPQL-----MKSR------------- 85
Cdd:PRK07003 10 WRPKDFASLVGQEHVVRALTHALDGGRLHHAyLFTGTRGVGKTT----LSR-IFAKALncetgVTSQpcgvcracreide 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 -----VLELNASDERGIsiirEKVKSFAKTTVTNKVDGYpcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLIC 160
Cdd:PRK07003 85 grfvdYVEMDAASNRGV----DEMAALLERAVYAPVDAR----FKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILAT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 161 NYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITfLQSAANLHQGTPITIS 240
Cdd:PRK07003 157 TDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALS-LTDQAIAYSANEVTET 235
|
250
....*....|....*....
gi 19115452 241 SVEELAGAVPYNIIRSLLD 259
Cdd:PRK07003 236 AVSGMLGALDQTYMVRLLD 254
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
44-192 |
1.45e-08 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 55.42 E-value: 1.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 44 KKTLLSNNLPHM-LFYGSPGTGKTstILA--LSRELFGPQLMKSRV--LELNASDERGISI--IREKVKSfakttvTNKv 116
Cdd:PRK05564 17 KNSIIKNRFSHAhIIVGEDGIGKS--LLAkeIALKILGKSQQREYVdiIEFKPINKKSIGVddIRNIIEE------VNK- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 117 dgypcPPF----KIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLE 192
Cdd:PRK05564 88 -----KPYegdkKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEEIEKFIS 162
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
54-244 |
2.19e-08 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 54.12 E-value: 2.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 54 HMLFYGSPGTGKTSTILALSRELfgpqlmKSRVLELNASdergiSIIrekvKSFAKTTVTN------KVDGYPCppfkII 127
Cdd:COG1223 37 KILFYGPPGTGKTMLAEALAGEL------KLPLLTVRLD-----SLI----GSYLGETARNlrklfdFARRAPC----VI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 128 ILDEADSMtqdaqaALRRTMES----YARIT------------RFCLIC--NYmTRIIDP-LSSRCS-KYRFKPLDNENM 187
Cdd:COG1223 98 FFDEFDAI------AKDRGDQNdvgeVKRVVnallqeldglpsGSVVIAatNH-PELLDSaLWRRFDeVIEFPLPDKEER 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 188 VKRLEFIAADQAVSMEP---GVVNALVECSGGDMRKAITFLQSAANLHQGTPITISSVEE 244
Cdd:COG1223 171 KEILELNLKKFPLPFELdlkKLAKKLEGLSGADIEKVLKTALKKAILEDREKVTKEDLEE 230
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
54-179 |
4.18e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 51.61 E-value: 4.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 54 HMLFYGSPGTGKTSTILALSRELFGPQlmkSRVLELNASDERGISIIREKVKSFAKTTVTNKVDGYPC--------PPFK 125
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPG---GGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRlalalarkLKPD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19115452 126 IIILDEADSMTQDAQAALRRTMESYARITRFC--------LICNYMTRIIDPLSSRCSKYRF 179
Cdd:smart00382 81 VLILDEITSLLDAEQEALLLLLEELRLLLLLKseknltviLTTNDEKDLGPALLRRRFDRRI 142
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
25-180 |
1.38e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 53.03 E-value: 1.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTST--ILALSRELFGP----------------QLMKSR 85
Cdd:PRK14956 12 YRPQFFRDVIHQDLAIGALQNALKSGKIGHAyIFFGPRGVGKTTIarILAKRLNCENPignepcnectscleitKGISSD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTR 165
Cdd:PRK14956 92 VLEIDAASNRGIENIRELRDNVKFAPMGGK--------YKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHK 163
|
170
....*....|....*
gi 19115452 166 IIDPLSSRCSKYRFK 180
Cdd:PRK14956 164 IPETILSRCQDFIFK 178
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
25-259 |
1.56e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 52.78 E-value: 1.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTILALSRELFGPQLMKSR------------------ 85
Cdd:PRK14957 10 YRPQSFAEVAGQQHALNSLVHALETQKVHHAyLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEpcnkcencvainnnsfid 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 86 VLELNASDERGISIIREKVKSFAKTTVTNKvdgypcppFKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTR 165
Cdd:PRK14957 90 LIEIDAASRTGVEETKEILDNIQYMPSQGR--------YKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 166 IIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITISSVEEL 245
Cdd:PRK14957 162 IPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGE-LKQAQIKQM 240
|
250
....*....|....*...
gi 19115452 246 AGAVP----YNIIRSLLD 259
Cdd:PRK14957 241 LGIIDseevYSIINAIID 258
|
|
| HolA |
COG1466 |
DNA polymerase III, delta subunit [Replication, recombination and repair]; |
122-290 |
2.53e-07 |
|
DNA polymerase III, delta subunit [Replication, recombination and repair];
Pssm-ID: 441075 [Multi-domain] Cd Length: 305 Bit Score: 51.41 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 122 PPF----KIIILDEADSMTQ--DAQAALRRTMESYARITRFCLICNYM---TRIIDPLSSRCSKYRFKPLDNENMVKRLE 192
Cdd:COG1466 57 LSLfgerRLVIVRNAEFLKKpgEGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIR 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 193 FIAADQAVSMEPGVVNALVECSGGDMRKAITFLQS-AANLHQGTPITISSVEELAGAVP-YNIIRsLLDTAYTKNVSNIE 270
Cdd:COG1466 137 QRLKAAGLRIDPDAAQLLAERVGGDLLALAQELEKlALYAGDGGTITLEDVEALVGDSAeFNVFD-LADALLAGDAARAL 215
|
170 180
....*....|....*....|
gi 19115452 271 TLSRDVAAEGYSTGIILSQL 290
Cdd:COG1466 216 RILRRLLAEGEEPVLILAAL 235
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
182-244 |
2.89e-07 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 47.08 E-value: 2.89e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 19115452 182 LDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTPITISSVEE 244
Cdd:cd18133 1 LDQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDDGKISLDRVYQ 63
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
25-259 |
5.01e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 51.05 E-value: 5.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPH-MLFYGSPGTGKTSTILALSRELFGPQLMKS------------------- 84
Cdd:PRK14955 10 YRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAARVFAKAVNCQRMIDDadylqevtepcgecescrd 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 85 -------RVLELNASDERG---ISIIREKVKSfakttvtnkvdGYPCPPFKIIILDEADSMTQDAQAALRRTMESYARIT 154
Cdd:PRK14955 90 fdagtslNISEFDAASNNSvddIRLLRENVRY-----------GPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 155 RFCLICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAanlhqg 234
Cdd:PRK14955 159 IFIFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQV------ 232
|
250 260
....*....|....*....|....*
gi 19115452 235 tpITISSVEELAGAVPYNIIRSLLD 259
Cdd:PRK14955 233 --IAFSVESEGEGSIRYDKVAELLN 255
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
55-244 |
1.16e-06 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 49.18 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 55 MLFYGSPGTGKTSTILALSRELFG------PQLMKSRVL------ELNASDERG-ISIIREKVKSFAKTTvtnkvdGYPc 121
Cdd:COG2842 53 GVVYGESGVGKTTAAREYANRNPNviyvtaSPSWTSKELleelaeELGIPAPPGtIADLRDRILERLAGT------GRL- 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 122 ppfkiIILDEADSMTQDAQAALRR-------------TMESYARITRFclicnymtriiDPLSSRCSK-YRFKPLDNEN- 186
Cdd:COG2842 126 -----LIIDEADHLKPKALEELRDihdetgvgvvligMERLPAKLKRY-----------EQLYSRIGFwVEFKPLSLEDv 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 19115452 187 --MVKRLEFIAadqavsmEPGVVNALVECSGGDMR---KAITFLQSAANLHQGTPITISSVEE 244
Cdd:COG2842 190 raLAEAWGELT-------DPDLLELLHRITRGNLRrldRTLRLAARAAKRNGLTKITLDHVRA 245
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
25-295 |
1.77e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 49.34 E-value: 1.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTSTilalsrelfgpqlmkSRVLELNASDERGISI---- 99
Cdd:PRK14958 10 WRPRCFQEVIGQAPVVRALSNALDQQYLHHAyLFTGTRGVGKTTI---------------SRILAKCLNCEKGVSAnpcn 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 100 ----IRE----------KVKSFAKTTVTNK---VDGYPCPP----FKIIILDEADSMTQDAQAALRRTMESYARITRFCL 158
Cdd:PRK14958 75 dcenCREidegrfpdlfEVDAASRTKVEDTrelLDNIPYAPtkgrFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFIL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 159 ICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpIT 238
Cdd:PRK14958 155 ATTDHHKLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGK-VL 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19115452 239 ISSVEELAGAVP----YNIIRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQLHDVLL 295
Cdd:PRK14958 234 IADVKTMLGTIEplllFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAI 294
|
|
| PRK07399 |
PRK07399 |
DNA polymerase III subunit delta'; Validated |
36-187 |
2.44e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236011 [Multi-domain] Cd Length: 314 Bit Score: 48.36 E-value: 2.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 36 QESTVQVLKKTLLSNNL-PHMLFYGSPGTGKTSTILALSRELF--GPQ--LMKSRVLELNASD----------------- 93
Cdd:PRK07399 9 QPLAIELLTAAIKQNRIaPAYLFAGPEGVGRKLAALCFIEGLLsqGSPskNIRRRLEEGNHPDllwveptyqhqgklita 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 94 ---------ERGISIIR-EKVKSFakTTVTNKvdgypcPPF----KIIILDEADSMTQDAQAALRRTMESYARITrFCLI 159
Cdd:PRK07399 89 seaeeaglkRKAPPQIRlEQIREI--KRFLSR------PPLeaprKVVVIEDAETMNEAAANALLKTLEEPGNGT-LILI 159
|
170 180
....*....|....*....|....*...
gi 19115452 160 CNYMTRIIDPLSSRCSKYRFKPLDNENM 187
Cdd:PRK07399 160 APSPESLLPTIVSRCQIIPFYRLSDEQL 187
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
20-155 |
4.69e-06 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 46.49 E-value: 4.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 20 PWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPH-----MLFYGSPGTGKTSTILALSRELfGPQL------MKSRVLE 88
Cdd:pfam03215 8 QWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL-GPKYrewsnpTSFRSPP 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19115452 89 LNASDERGISIIREKVKSF-----------AKTTVTNKVDGYPCPPFKIIILDEADSMTQDAQAALRRTMESYARITR 155
Cdd:pfam03215 87 NQVTDFRGDCIVNSRFLSQmesfsefelkgARYLVMQKRGKNAQGNKKLILIEDLPNVFHIDTRRFQQVIRQWLYSSE 164
|
|
| PRK07471 |
PRK07471 |
DNA polymerase III subunit delta'; Validated |
125-235 |
7.91e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236022 [Multi-domain] Cd Length: 365 Bit Score: 46.95 E-value: 7.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 125 KIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSKYRFKPLDNENMVKrlefIAADQAVSMEP 204
Cdd:PRK07471 143 RVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVID----ALAAAGPDLPD 218
|
90 100 110
....*....|....*....|....*....|..
gi 19115452 205 GVVNALVECSGGDMRKAITFL-QSAANLHQGT 235
Cdd:PRK07471 219 DPRAALAALAEGSVGRALRLAgGDGLALYRRL 250
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
54-244 |
9.05e-06 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 47.21 E-value: 9.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 54 HMLFYGSPGTGKTSTILALSRELFGPqlmksrVLELNASD---------ERGISIIREKVKSFAkttvtnkvdgyPCppf 124
Cdd:COG0464 193 GLLLYGPPGTGKTLLARALAGELGLP------LIEVDLSDlvskyvgetEKNLREVFDKARGLA-----------PC--- 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 125 kIIILDEADSM----TQDAQAALRRT-------MESYARitRFCLIC--NYMtRIIDP-LSSRC-SKYRFKPLDNENMVK 189
Cdd:COG0464 253 -VLFIDEADALagkrGEVGDGVGRRVvntllteMEELRS--DVVVIAatNRP-DLLDPaLLRRFdEIIFFPLPDAEERLE 328
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 19115452 190 RLEFIAADQAVSME---PGVVNALVECSGGDMRKAITFLQSAANLHQGTPITISSVEE 244
Cdd:COG0464 329 IFRIHLRKRPLDEDvdlEELAEATEGLSGADIRNVVRRAALQALRLGREPVTTEDLLE 386
|
|
| PRK08058 |
PRK08058 |
DNA polymerase III subunit delta'; Validated |
40-192 |
1.79e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181214 [Multi-domain] Cd Length: 329 Bit Score: 46.07 E-value: 1.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 40 VQVLKKTLLSNNLPH-MLFYGSPGTGKTSTILALSRELFGPQLMKS----------RVLELNASDER-----GISI---- 99
Cdd:PRK08058 15 VKMLQNSIAKNRLSHaYLFEGAKGTGKKATALWLAKSLFCLERNGVepcgtctnckRIDSGNHPDVHlvapdGQSIkkdq 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 100 IREKVKSFAKTTV-TNKvdgypcppfKIIILDEADSMTqdAQAA---LRRTMESYARITRFCLICNYmTRIIDPLSSRCS 175
Cdd:PRK08058 95 IRYLKEEFSKSGVeSNK---------KVYIIEHADKMT--ASAAnslLKFLEEPSGGTTAILLTENK-HQILPTILSRCQ 162
|
170
....*....|....*..
gi 19115452 176 KYRFKPLDNENMVKRLE 192
Cdd:PRK08058 163 VVEFRPLPPESLIQRLQ 179
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
47-260 |
3.24e-05 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 45.22 E-value: 3.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 47 LLSNNLPHMLF-YGSPGTGKTSTILALSREL---FGPQLMKSRVLELNASD----------------------ERGIS-- 98
Cdd:COG1474 45 ALRGERPSNVLiYGPTGTGKTAVAKYVLEELeeeAEERGVDVRVVYVNCRQastryrvlsrileelgsgedipSTGLStd 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 99 ----IIREKVKSFAKTTvtnkvdgypcppfkIIILDEADSMTQDAQ----AALRRTMESY--ARITrFCLICNYMTrIID 168
Cdd:COG1474 125 elfdRLYEALDERDGVL--------------VVVLDEIDYLVDDEGddllYQLLRANEELegARVG-VIGISNDLE-FLE 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 169 PLSSR------CSKYRFKPLDNENMVKRLEFiAADQAVsmEPGVVN--------ALVECSGGDMRKAITFLQSAANL--H 232
Cdd:COG1474 189 NLDPRvksslgEEEIVFPPYDADELRDILED-RAELAF--YDGVLSdevipliaALAAQEHGDARKAIDLLRVAGEIaeR 265
|
250 260
....*....|....*....|....*....
gi 19115452 233 QGTP-ITISSVEELAGAVPYNIIRSLLDT 260
Cdd:COG1474 266 EGSDrVTEEHVREAREKIERDRLLEVLRG 294
|
|
| HLD_clamp_pol_III_gamma_tau |
cd18137 |
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ... |
182-247 |
6.89e-05 |
|
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.
Pssm-ID: 350839 [Multi-domain] Cd Length: 65 Bit Score: 40.18 E-value: 6.89e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19115452 182 LDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTpITISSVEELAG 247
Cdd:cd18137 1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGR-VTLDDVREMLG 65
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
182-247 |
7.05e-05 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 40.69 E-value: 7.05e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19115452 182 LDNENMVKRL------EFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGT---PITISSVEELAG 247
Cdd:cd18139 1 LSEEDLEKLLkraledKERGGDRKVTIDDEALELLAEAADGDARSALNLLELAVLSAEEDggiVITLEDLEEVLQ 75
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
55-197 |
8.20e-05 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 43.74 E-value: 8.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 55 MLFYGSPGTGKTSTILALS------RELFGPQLMKSRVLELNAsdERGISIIREKVKSFAKttvtnkvdGYPCPPF---- 124
Cdd:COG3598 16 TLLAGPPGTGKSFLALQLAaavaagGPWLGRRVPPGKVLYLAA--EDDRGELRRRLKALGA--------DLGLPFAdldg 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 125 KIIILDEADSMT-QDAQAALRRTMESYaritRFCLIcnymtrIIDPLssrcskYRFKPLD---NENM---VKRLEFIAAD 197
Cdd:COG3598 86 RLRLLSLAGDLDdTDDLEALERAIEEE----GPDLV------VIDPL------ARVFGGDendAEEMrafLNPLDRLAER 149
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
26-76 |
8.42e-05 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 42.49 E-value: 8.42e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 19115452 26 RPKTLDQVSSQESTVQVLK---KTLLSNN--LPHMLFYGSPGTGKTSTILALSREL 76
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKifiEAAKQRGeaLDHVLLYGPPGLGKTTLANIIANEM 57
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
26-76 |
1.60e-04 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 42.81 E-value: 1.60e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 19115452 26 RPKTLDQVSSQESTVQVLK------KtLLSNNLPHMLFYGSPGTGKTStiLA--LSREL 76
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKifieaaK-KRGEALDHVLLYGPPGLGKTT--LAniIANEM 75
|
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
200-247 |
2.78e-04 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 38.99 E-value: 2.78e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 19115452 200 VSMEPGVVNALVECSGGDMRKAITFLQSAANL----HQGTPITISSVEELAG 247
Cdd:pfam16193 5 IELDDEALEALAELADGDARRALNALELAVLStppdDGGIHITLEILEEALQ 56
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
56-136 |
4.82e-04 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 40.35 E-value: 4.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 56 LFYGSPGTGKTSTILALSRE-------LFGPQLMKSRVLElnasDERGISIIREKVKSFAkttvtnkvdgyPCppfkIII 128
Cdd:cd19503 38 LLHGPPGTGKTLLARAVANEaganflsISGPSIVSKYLGE----SEKNLREIFEEARSHA-----------PS----IIF 98
|
....*...
gi 19115452 129 LDEADSMT 136
Cdd:cd19503 99 IDEIDALA 106
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
55-138 |
9.65e-04 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 39.19 E-value: 9.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 55 MLFYGSPGTGKTSTILALSRELfGPQLMK---SRVLE--LNASDERGISIIREkvksfAKTTVtnkvdgyPCppfkIIIL 129
Cdd:cd19481 29 ILLYGPPGTGKTLLAKALAGEL-GLPLIVvklSSLLSkyVGESEKNLRKIFER-----ARRLA-------PC----ILFI 91
|
....*....
gi 19115452 130 DEADSMTQD 138
Cdd:cd19481 92 DEIDAIGRK 100
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
26-76 |
1.89e-03 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 39.68 E-value: 1.89e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 19115452 26 RPKTLDQVSSQESTVQVLKKTL---LSNN--LPHMLFYGSPGTGKT--STILAlsREL 76
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFIeaaKKRGeaLDHVLLYGPPGLGKTtlAHIIA--NEM 78
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
25-73 |
2.11e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 39.97 E-value: 2.11e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 19115452 25 YRPKTLDQVSSQESTVQVLKKTLLSNNLPHM-LFYGSPGTGKTST--ILALS 73
Cdd:PRK07764 9 YRPATFAEVIGQEHVTEPLSTALDSGRINHAyLFSGPRGCGKTSSarILARS 60
|
|
| AAA_7 |
pfam12775 |
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 ... |
45-76 |
2.19e-03 |
|
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 proteins. Cytoplasmic dynein-2 (dynein-2) performs intraflagellar transport and is associated with human skeletal ciliopathies. Dyneins share a conserved motor domain that couples cycles of ATP hydrolysis with conformational changes to produce movement. Structural analysis reveal that the motor's ring consists of six AAA+ domains (ATPases associated with various cellular activities (AAA1-AAA6). This is the third nucleotide binding sites in the dynein motor. However, AAA3 has lost the catalytic residues necessary for ATP hydrolysis (the Walker B glutamate, the arginine finger, sensor-I and sensor-II motifs).
Pssm-ID: 463698 [Multi-domain] Cd Length: 179 Bit Score: 38.53 E-value: 2.19e-03
10 20 30
....*....|....*....|....*....|..
gi 19115452 45 KTLLSNNLPhMLFYGSPGTGKTSTILALSREL 76
Cdd:pfam12775 25 DLLLKNGKP-VLLVGPTGTGKTVIIQNLLRKL 55
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
56-136 |
2.35e-03 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 38.03 E-value: 2.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 56 LFYGSPGTGKTSTILALSRE-------LFGPQLMKSRVLElnasDERGISIIREKVKSFAkttvtnkvdgyPCppfkIII 128
Cdd:cd19511 31 LLYGPPGCGKTLLAKALASEaglnfisVKGPELFSKYVGE----SERAVREIFQKARQAA-----------PC----IIF 91
|
....*...
gi 19115452 129 LDEADSMT 136
Cdd:cd19511 92 FDEIDSLA 99
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
32-137 |
2.71e-03 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 39.44 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 32 QVSSQESTVQVlKKTLLSNNLP------HMLFYGSPGTGKTSTILALSRELFGPQLM-KSRVLELNASDERGISIIREKV 104
Cdd:TIGR03922 287 QVAALKSSTAM-ALARAERGLPvaqtsnHMLFAGPPGTGKTTIARVVAKIYCGLGVLrKPLVREVSRADLIGQYIGESEA 365
|
90 100 110
....*....|....*....|....*....|...
gi 19115452 105 KSFAktTVTNKVDGypcppfkIIILDEADSMTQ 137
Cdd:TIGR03922 366 KTNE--IIDSALGG-------VLFLDEAYTLVE 389
|
|
| DEXXQc_DNA2 |
cd18041 |
DEXXQ-box helicase domain of DNA2; DNA2 (DNA Replication Helicase/Nuclease 2) possesses ... |
41-76 |
4.30e-03 |
|
DEXXQ-box helicase domain of DNA2; DNA2 (DNA Replication Helicase/Nuclease 2) possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5-3 helicase, and endonuclease activities, and is involved in DNA replication and DNA repair in the nucleus and mitochondrion. It is involved in Okazaki fragment processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. It is also involved in 5-end resection of DNA during double-strand break (DSB) repair; it is recruited by BLM and mediates the cleavage of 5-ssDNA, while the 3-ssDNA cleavage is prevented by the presence of RPA. DNA2 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350799 [Multi-domain] Cd Length: 203 Bit Score: 37.99 E-value: 4.30e-03
10 20 30
....*....|....*....|....*....|....*.
gi 19115452 41 QVLKKTLLSNNlpHMLFYGSPGTGKTSTILALSREL 76
Cdd:cd18041 8 QAIKKVLNAKD--YALILGMPGTGKTTTIAALVRIL 41
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
54-159 |
4.44e-03 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 36.94 E-value: 4.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 54 HMLFYGSPGTGKTSTILALSRELfgpQLMKSRVLELNASDERGISIIREKV-------------KSFAKTTVTNKVDGYP 120
Cdd:pfam13401 7 ILVLTGESGTGKTTLLRRLLEQL---PEVRDSVVFVDLPSGTSPKDLLRALlralglplsgrlsKEELLAALQQLLLALA 83
|
90 100 110
....*....|....*....|....*....|....*....
gi 19115452 121 CPPfkIIILDEADSMTQDAQAALRRTMESYARITRFCLI 159
Cdd:pfam13401 84 VAV--VLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
45-153 |
5.84e-03 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 36.76 E-value: 5.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115452 45 KTLLSNNLphMLFYGSPGTGKTSTILALSRELfgpQLMKSRVLeLNASDERGISIIREKVKSFAKT----------TVTN 114
Cdd:cd17933 7 RLVLRNRV--SVLTGGAGTGKTTTLKALLAAL---EAEGKRVV-LAAPTGKAAKRLSESTGIEASTihrllginpgGGGF 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 19115452 115 KVDGYPCPPFKIIILDEAdSM-TQDAQAALRRTMESYARI 153
Cdd:cd17933 81 YYNEENPLDADLLIVDEA-SMvDTRLMAALLSAIPAGARL 119
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
124-181 |
9.55e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 37.48 E-value: 9.55e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 19115452 124 FKIIILDEADSMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSKYRFKP 181
Cdd:PRK06090 109 YRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTP 166
|
|
| |
