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Conserved domains on  [gi|19115556|ref|NP_594644|]
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DNA repair protein Rhp41 [Schizosaccharomyces pombe]

Protein Classification

RAD4 DNA repair family protein( domain architecture ID 11489429)

RAD4 DNA repair family protein such as DNA repair protein RAD4, a DNA damage recognition protein that is involved in the nucleotide excision repair (NER) pathway, which is responsible for removing a wide range of DNA lesions, including UV-induced photoproducts and chemical adducts.

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
rad4 TIGR00605
DNA repair protein rad4; All proteins in this family for which functions are known are ...
1-638 0e+00

DNA repair protein rad4; All proteins in this family for which functions are known are involved in targeting nucleotide excision repair to specific regions of the genome.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 273170 [Multi-domain]  Cd Length: 713  Bit Score: 908.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556     1 MMSDEDNTYSDDEEWLDLDLGLPNNDIKTAPILNSSLLSSAVHGERLIQERPTHDFG---DVEATVDRTVEKRSRLKITS 77
Cdd:TIGR00605  61 LMCNLDSTHSDDRVVSVPDSLSVSEEIPSREEDYDSREFEDVYLSNLVAEFETISVEikpSSKAESDDDAETLSRNVCSN 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556    78 VDRKIRLQIHQLHLLCLTYHLCTRNTWCDD--NRLNYLVKYIPPGIRVSLHPSSQKSQMIRNKTFLHGLAGLVEVWKRKY 155
Cdd:TIGR00605 141 EARKDRKYIHILYLLCLMVHLFTRNEWSLSapLKSAKLSNLIPEKVRLLLHPSVRKSEELPSRSLRGLRKPLVEKLKKCM 220
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   156 KITTNGLRKPNYGLLQNNSLISESLS-LEEFCKNSKLLSGSRDYGTQLFASILRNLNVPTRLVFSLQVLSFRFKGAINEA 234
Cdd:TIGR00605 221 ETWQKGLRKTTKGLLKLLNGGRYSRSkWEEIEKSSNRKLGGRKYRTLKRGSILENLNVPTRLVFSDFLLSVSKGHNDPEI 300
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   235 SSHEIVPAWSQQMENDSSSDISESAHITSRFRKRRKIIQPSFSNLSHLDASDIVTEDTKLKVIDSPK--PVFWVEAFNKA 312
Cdd:TIGR00605 301 SSEGFVPKLSACNANQRLIMSCESADRTSRFRMKKDPSLPGFSAYSDMDKSPIFTCEEGDKFIDRWItyVDFWVEVFIEQ 380
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   313 MQKWVCVDPFGDASVIGKYRRFEPASsdhlNQMTYVFAIEANGYVKDVTRKYCLHYY-KILKNRVEIFPFGKAWMNRIFS 391
Cdd:TIGR00605 381 EEKWVCVDAVHSGVVPKGVTCFEPAT----LMMTYVFAYDRDGYVKDVTRRYCDQWStKVRKRRVEKADFGETWFRPIFG 456
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   392 KIGKPRDFyndMDAIEDAELLRLEQSEGIPRNIQDLKDHPLFVLERHLKKNQAIKTGKSCGRINTKNGVELVYPRKYVSN 471
Cdd:TIGR00605 457 ALHKRKRT---IDDIEDQEFLRRHESEGIPKSIQDLKNHPLYVLERHLKKTQALKPGKKACTLGFVNGKAGVYSRKDVHD 533
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   472 GFSAEHWYRKGRIIKPGAQPLKHVKNG------------DKVLPLYDEEATQLYTPKPVVANIVPKNAYGNIDLYVPSML 539
Cdd:TIGR00605 534 LKSAEQWYKKGRVIKLGEQPYKVVKARartvrlpkgeaeEEDLGLYSYEQTELYIPPPAVDGIVPKNAYGNIDLFVPSMI 613
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   540 PYGAYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAIDLIAEEIDQEEKEAEARNVRKTCLLL 619
Cdd:TIGR00605 614 PKGAVHLRLPGAIKAAKKLNIDYAPAVTGFDFHRGYSKPVLDGIIVCEEFREAIETAWEEIEQIQEEKEQEKHRKRALGN 693
                         650
                  ....*....|....*....
gi 19115556   620 WKRLITGLRIRQRVFEEYG 638
Cdd:TIGR00605 694 WKTLLKGLRIRERLKETYG 712
 
Name Accession Description Interval E-value
rad4 TIGR00605
DNA repair protein rad4; All proteins in this family for which functions are known are ...
1-638 0e+00

DNA repair protein rad4; All proteins in this family for which functions are known are involved in targeting nucleotide excision repair to specific regions of the genome.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273170 [Multi-domain]  Cd Length: 713  Bit Score: 908.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556     1 MMSDEDNTYSDDEEWLDLDLGLPNNDIKTAPILNSSLLSSAVHGERLIQERPTHDFG---DVEATVDRTVEKRSRLKITS 77
Cdd:TIGR00605  61 LMCNLDSTHSDDRVVSVPDSLSVSEEIPSREEDYDSREFEDVYLSNLVAEFETISVEikpSSKAESDDDAETLSRNVCSN 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556    78 VDRKIRLQIHQLHLLCLTYHLCTRNTWCDD--NRLNYLVKYIPPGIRVSLHPSSQKSQMIRNKTFLHGLAGLVEVWKRKY 155
Cdd:TIGR00605 141 EARKDRKYIHILYLLCLMVHLFTRNEWSLSapLKSAKLSNLIPEKVRLLLHPSVRKSEELPSRSLRGLRKPLVEKLKKCM 220
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   156 KITTNGLRKPNYGLLQNNSLISESLS-LEEFCKNSKLLSGSRDYGTQLFASILRNLNVPTRLVFSLQVLSFRFKGAINEA 234
Cdd:TIGR00605 221 ETWQKGLRKTTKGLLKLLNGGRYSRSkWEEIEKSSNRKLGGRKYRTLKRGSILENLNVPTRLVFSDFLLSVSKGHNDPEI 300
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   235 SSHEIVPAWSQQMENDSSSDISESAHITSRFRKRRKIIQPSFSNLSHLDASDIVTEDTKLKVIDSPK--PVFWVEAFNKA 312
Cdd:TIGR00605 301 SSEGFVPKLSACNANQRLIMSCESADRTSRFRMKKDPSLPGFSAYSDMDKSPIFTCEEGDKFIDRWItyVDFWVEVFIEQ 380
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   313 MQKWVCVDPFGDASVIGKYRRFEPASsdhlNQMTYVFAIEANGYVKDVTRKYCLHYY-KILKNRVEIFPFGKAWMNRIFS 391
Cdd:TIGR00605 381 EEKWVCVDAVHSGVVPKGVTCFEPAT----LMMTYVFAYDRDGYVKDVTRRYCDQWStKVRKRRVEKADFGETWFRPIFG 456
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   392 KIGKPRDFyndMDAIEDAELLRLEQSEGIPRNIQDLKDHPLFVLERHLKKNQAIKTGKSCGRINTKNGVELVYPRKYVSN 471
Cdd:TIGR00605 457 ALHKRKRT---IDDIEDQEFLRRHESEGIPKSIQDLKNHPLYVLERHLKKTQALKPGKKACTLGFVNGKAGVYSRKDVHD 533
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   472 GFSAEHWYRKGRIIKPGAQPLKHVKNG------------DKVLPLYDEEATQLYTPKPVVANIVPKNAYGNIDLYVPSML 539
Cdd:TIGR00605 534 LKSAEQWYKKGRVIKLGEQPYKVVKARartvrlpkgeaeEEDLGLYSYEQTELYIPPPAVDGIVPKNAYGNIDLFVPSMI 613
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   540 PYGAYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAIDLIAEEIDQEEKEAEARNVRKTCLLL 619
Cdd:TIGR00605 614 PKGAVHLRLPGAIKAAKKLNIDYAPAVTGFDFHRGYSKPVLDGIIVCEEFREAIETAWEEIEQIQEEKEQEKHRKRALGN 693
                         650
                  ....*....|....*....
gi 19115556   620 WKRLITGLRIRQRVFEEYG 638
Cdd:TIGR00605 694 WKTLLKGLRIRERLKETYG 712
RAD4 COG5535
DNA repair protein RAD4 [DNA replication, recombination, and repair];
1-638 0e+00

DNA repair protein RAD4 [DNA replication, recombination, and repair];


Pssm-ID: 227822 [Multi-domain]  Cd Length: 650  Bit Score: 838.35  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   1 MMSDEDNTYSDDEEWLDLDLGLPNNDIKTAPILNSSLLSSAVHGERLIQERPTHDFGDVEATVDRTVEKRSRLKITSVDR 80
Cdd:COG5535   1 MKRDLENSYNDQARRKNSKIEKKNVSFKEEEEVDSSFDSFYQDEEKDIDEEPVELDGDLTVTVNNIRRDRSKVSKYSDDH 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556  81 KIRLQIHQLHLLCLTYH-LCTRNTWCDDNRLNYLVKYIPP--GIRVSLHPSSQKSQMIRNKTFLHGLAGLVEVWKRKyKI 157
Cdd:COG5535  81 NEKLQSSQLHLIMIPFMlLKSRNKWIDDERLNRRLKRSVPklGGKSFKDWSVRKSAHIMDSTCLLLLGFIRNLWFRS-KM 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 158 TTNGLRkPNYGLLQNNSLISESLSLEEFCKNSKLLSGSRDYGTQLFASILRNLNVPTRLVFSLQVLSFRFKGAINEASSH 237
Cdd:COG5535 160 LSNGLR-FNRLEKQIKYLDNQNESSISESTYKKLLEGLRFYGNKPFKNIGVEDNRKLAKRTMKQMESSDFWEEIFENYSL 238
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 238 EIVPAWSQQMENDSSSD--ISESAHITSRFRKRRKIIQPSFSNLSHLDASDivteDTKLKVIDSPK-PVFWVEAFNKAMQ 314
Cdd:COG5535 239 EVVPLKSADGRRDADVRgfEAEHRILNVFARLIASLIQPVFSNNSDLDVLS----EGLLEYIDSLEyPGFWGEVVDKFEK 314
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 315 KWVCVDPFGDASVIG-KYRRFEPASSDHLNQMTYVFAIEANGYVKDVTRKYCLHYYKILKnRVEIFPFGKAWMNRIFSKI 393
Cdd:COG5535 315 KWVFVDPVRLYIVYSeLKCKFEPAASIHLNIMEYVGAYDACVYVKDVTLRYRDQSYSFLK-RITKHLFSVQYFVRQFPGL 393
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 394 GKPRDFyNDMDAIEDAELLRLEQSEGIPRNIQDLKDHPLFVLERHLKKNQAIKTGKSCGRINTK--NGVELVYPRKYVSN 471
Cdd:COG5535 394 GKCKEA-SDEEAIEDFDDLDERRSEGIPKSVQDLKRHPKFVLESHLKWNQAIKPGAKPGFTLTKgkNSVEAVYLRRDVVR 472
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 472 GFSAEHWYRKGRIIKPGAQPLKHVKN--------GDKVLP-LYDEEATQLYTPKPVVANIVPKNAYGNIDLYVPSMLPYG 542
Cdd:COG5535 473 LKSAEQWYRMGRVIKPGAQPLKIVKRmrervrnlDDKVIReLYSPEQTELYGPPLVVAGIIPKNMYGNIDYYVPSMIPRG 552
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 543 AYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAIDLIAEEIDQEEKEAEARNVRKTCLLLWKR 622
Cdd:COG5535 553 CVLIPNRNARDIARLLGIDYADAVTGFDFGRSTVKPVLRGIVVPKKNLEAISNFLAEYERIQEEKERSEVRLGGLKRWKI 632
                       650
                ....*....|....*.
gi 19115556 623 LITGLRIRQRVFEEYG 638
Cdd:COG5535 633 LLRKLRIRLRINEEYG 648
Rad4 pfam03835
Rad4 transglutaminase-like domain;
269-412 3.80e-48

Rad4 transglutaminase-like domain;


Pssm-ID: 427539 [Multi-domain]  Cd Length: 146  Bit Score: 165.27  E-value: 3.80e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   269 RKIIQPSFSNLSHLDASDI--VTEDTKLKVIDSPKPVFWVEAFNKAMQKWVCVDPFGDASvIGKYRRFEPA-SSDHLNQM 345
Cdd:pfam03835   1 KSLQPPSFSSLKSDDSSPKsdKRETSRLKDKDLPYPVYWVEVFNPETKKWISVDPLVLKT-IELKSKFEPRiAEKALNVM 79
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19115556   346 TYVFAIEANGYVKDVTRKYCLHYY-KILKNRVEIFPFGKAWMNRIFSKIGKPRDFYNdMDAIEDAELL 412
Cdd:pfam03835  80 TYVVAFDSDGGAKDVTRRYCSTYNaKTRKRRIERTDDGKDWWESVLRPYNKPNREAS-RDDYEDAELL 146
BHD_3 smart01032
Rad4 beta-hairpin domain 3; This short domain is found in the Rad4 protein. This domain binds ...
523-593 9.33e-32

Rad4 beta-hairpin domain 3; This short domain is found in the Rad4 protein. This domain binds to DNA.


Pssm-ID: 198100 [Multi-domain]  Cd Length: 75  Bit Score: 117.66  E-value: 9.33e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19115556    523 VPKNAYGNIDLYVPSMLPYGAYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAI 593
Cdd:smart01032   1 VPRNEYGNIDLFKPSMLPIGCVHLKLPGLIRVAKRLGIDYAPAVTGFDFKRGSAHPVIDGVVVAEEFAEAL 71
 
Name Accession Description Interval E-value
rad4 TIGR00605
DNA repair protein rad4; All proteins in this family for which functions are known are ...
1-638 0e+00

DNA repair protein rad4; All proteins in this family for which functions are known are involved in targeting nucleotide excision repair to specific regions of the genome.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273170 [Multi-domain]  Cd Length: 713  Bit Score: 908.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556     1 MMSDEDNTYSDDEEWLDLDLGLPNNDIKTAPILNSSLLSSAVHGERLIQERPTHDFG---DVEATVDRTVEKRSRLKITS 77
Cdd:TIGR00605  61 LMCNLDSTHSDDRVVSVPDSLSVSEEIPSREEDYDSREFEDVYLSNLVAEFETISVEikpSSKAESDDDAETLSRNVCSN 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556    78 VDRKIRLQIHQLHLLCLTYHLCTRNTWCDD--NRLNYLVKYIPPGIRVSLHPSSQKSQMIRNKTFLHGLAGLVEVWKRKY 155
Cdd:TIGR00605 141 EARKDRKYIHILYLLCLMVHLFTRNEWSLSapLKSAKLSNLIPEKVRLLLHPSVRKSEELPSRSLRGLRKPLVEKLKKCM 220
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   156 KITTNGLRKPNYGLLQNNSLISESLS-LEEFCKNSKLLSGSRDYGTQLFASILRNLNVPTRLVFSLQVLSFRFKGAINEA 234
Cdd:TIGR00605 221 ETWQKGLRKTTKGLLKLLNGGRYSRSkWEEIEKSSNRKLGGRKYRTLKRGSILENLNVPTRLVFSDFLLSVSKGHNDPEI 300
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   235 SSHEIVPAWSQQMENDSSSDISESAHITSRFRKRRKIIQPSFSNLSHLDASDIVTEDTKLKVIDSPK--PVFWVEAFNKA 312
Cdd:TIGR00605 301 SSEGFVPKLSACNANQRLIMSCESADRTSRFRMKKDPSLPGFSAYSDMDKSPIFTCEEGDKFIDRWItyVDFWVEVFIEQ 380
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   313 MQKWVCVDPFGDASVIGKYRRFEPASsdhlNQMTYVFAIEANGYVKDVTRKYCLHYY-KILKNRVEIFPFGKAWMNRIFS 391
Cdd:TIGR00605 381 EEKWVCVDAVHSGVVPKGVTCFEPAT----LMMTYVFAYDRDGYVKDVTRRYCDQWStKVRKRRVEKADFGETWFRPIFG 456
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   392 KIGKPRDFyndMDAIEDAELLRLEQSEGIPRNIQDLKDHPLFVLERHLKKNQAIKTGKSCGRINTKNGVELVYPRKYVSN 471
Cdd:TIGR00605 457 ALHKRKRT---IDDIEDQEFLRRHESEGIPKSIQDLKNHPLYVLERHLKKTQALKPGKKACTLGFVNGKAGVYSRKDVHD 533
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   472 GFSAEHWYRKGRIIKPGAQPLKHVKNG------------DKVLPLYDEEATQLYTPKPVVANIVPKNAYGNIDLYVPSML 539
Cdd:TIGR00605 534 LKSAEQWYKKGRVIKLGEQPYKVVKARartvrlpkgeaeEEDLGLYSYEQTELYIPPPAVDGIVPKNAYGNIDLFVPSMI 613
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   540 PYGAYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAIDLIAEEIDQEEKEAEARNVRKTCLLL 619
Cdd:TIGR00605 614 PKGAVHLRLPGAIKAAKKLNIDYAPAVTGFDFHRGYSKPVLDGIIVCEEFREAIETAWEEIEQIQEEKEQEKHRKRALGN 693
                         650
                  ....*....|....*....
gi 19115556   620 WKRLITGLRIRQRVFEEYG 638
Cdd:TIGR00605 694 WKTLLKGLRIRERLKETYG 712
RAD4 COG5535
DNA repair protein RAD4 [DNA replication, recombination, and repair];
1-638 0e+00

DNA repair protein RAD4 [DNA replication, recombination, and repair];


Pssm-ID: 227822 [Multi-domain]  Cd Length: 650  Bit Score: 838.35  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   1 MMSDEDNTYSDDEEWLDLDLGLPNNDIKTAPILNSSLLSSAVHGERLIQERPTHDFGDVEATVDRTVEKRSRLKITSVDR 80
Cdd:COG5535   1 MKRDLENSYNDQARRKNSKIEKKNVSFKEEEEVDSSFDSFYQDEEKDIDEEPVELDGDLTVTVNNIRRDRSKVSKYSDDH 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556  81 KIRLQIHQLHLLCLTYH-LCTRNTWCDDNRLNYLVKYIPP--GIRVSLHPSSQKSQMIRNKTFLHGLAGLVEVWKRKyKI 157
Cdd:COG5535  81 NEKLQSSQLHLIMIPFMlLKSRNKWIDDERLNRRLKRSVPklGGKSFKDWSVRKSAHIMDSTCLLLLGFIRNLWFRS-KM 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 158 TTNGLRkPNYGLLQNNSLISESLSLEEFCKNSKLLSGSRDYGTQLFASILRNLNVPTRLVFSLQVLSFRFKGAINEASSH 237
Cdd:COG5535 160 LSNGLR-FNRLEKQIKYLDNQNESSISESTYKKLLEGLRFYGNKPFKNIGVEDNRKLAKRTMKQMESSDFWEEIFENYSL 238
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 238 EIVPAWSQQMENDSSSD--ISESAHITSRFRKRRKIIQPSFSNLSHLDASDivteDTKLKVIDSPK-PVFWVEAFNKAMQ 314
Cdd:COG5535 239 EVVPLKSADGRRDADVRgfEAEHRILNVFARLIASLIQPVFSNNSDLDVLS----EGLLEYIDSLEyPGFWGEVVDKFEK 314
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 315 KWVCVDPFGDASVIG-KYRRFEPASSDHLNQMTYVFAIEANGYVKDVTRKYCLHYYKILKnRVEIFPFGKAWMNRIFSKI 393
Cdd:COG5535 315 KWVFVDPVRLYIVYSeLKCKFEPAASIHLNIMEYVGAYDACVYVKDVTLRYRDQSYSFLK-RITKHLFSVQYFVRQFPGL 393
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 394 GKPRDFyNDMDAIEDAELLRLEQSEGIPRNIQDLKDHPLFVLERHLKKNQAIKTGKSCGRINTK--NGVELVYPRKYVSN 471
Cdd:COG5535 394 GKCKEA-SDEEAIEDFDDLDERRSEGIPKSVQDLKRHPKFVLESHLKWNQAIKPGAKPGFTLTKgkNSVEAVYLRRDVVR 472
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 472 GFSAEHWYRKGRIIKPGAQPLKHVKN--------GDKVLP-LYDEEATQLYTPKPVVANIVPKNAYGNIDLYVPSMLPYG 542
Cdd:COG5535 473 LKSAEQWYRMGRVIKPGAQPLKIVKRmrervrnlDDKVIReLYSPEQTELYGPPLVVAGIIPKNMYGNIDYYVPSMIPRG 552
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556 543 AYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAIDLIAEEIDQEEKEAEARNVRKTCLLLWKR 622
Cdd:COG5535 553 CVLIPNRNARDIARLLGIDYADAVTGFDFGRSTVKPVLRGIVVPKKNLEAISNFLAEYERIQEEKERSEVRLGGLKRWKI 632
                       650
                ....*....|....*.
gi 19115556 623 LITGLRIRQRVFEEYG 638
Cdd:COG5535 633 LLRKLRIRLRINEEYG 648
Rad4 pfam03835
Rad4 transglutaminase-like domain;
269-412 3.80e-48

Rad4 transglutaminase-like domain;


Pssm-ID: 427539 [Multi-domain]  Cd Length: 146  Bit Score: 165.27  E-value: 3.80e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115556   269 RKIIQPSFSNLSHLDASDI--VTEDTKLKVIDSPKPVFWVEAFNKAMQKWVCVDPFGDASvIGKYRRFEPA-SSDHLNQM 345
Cdd:pfam03835   1 KSLQPPSFSSLKSDDSSPKsdKRETSRLKDKDLPYPVYWVEVFNPETKKWISVDPLVLKT-IELKSKFEPRiAEKALNVM 79
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19115556   346 TYVFAIEANGYVKDVTRKYCLHYY-KILKNRVEIFPFGKAWMNRIFSKIGKPRDFYNdMDAIEDAELL 412
Cdd:pfam03835  80 TYVVAFDSDGGAKDVTRRYCSTYNaKTRKRRIERTDDGKDWWESVLRPYNKPNREAS-RDDYEDAELL 146
BHD_3 pfam10405
Rad4 beta-hairpin domain 3; This short domain is found in the Rad4 protein. This domain binds ...
523-593 2.02e-32

Rad4 beta-hairpin domain 3; This short domain is found in the Rad4 protein. This domain binds to DNA.


Pssm-ID: 463079 [Multi-domain]  Cd Length: 73  Bit Score: 119.47  E-value: 2.02e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19115556   523 VPKNAYGNIDLYVPSMLPYGAYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAI 593
Cdd:pfam10405   1 VPKNAYGNIDIFVPSMLPEGCVHIPLPGAARAAKKLGIDYAPAVTGFDFKGRRGKPVIDGIVVAEEDEEAL 71
BHD_3 smart01032
Rad4 beta-hairpin domain 3; This short domain is found in the Rad4 protein. This domain binds ...
523-593 9.33e-32

Rad4 beta-hairpin domain 3; This short domain is found in the Rad4 protein. This domain binds to DNA.


Pssm-ID: 198100 [Multi-domain]  Cd Length: 75  Bit Score: 117.66  E-value: 9.33e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19115556    523 VPKNAYGNIDLYVPSMLPYGAYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAI 593
Cdd:smart01032   1 VPRNEYGNIDLFKPSMLPIGCVHLKLPGLIRVAKRLGIDYAPAVTGFDFKRGSAHPVIDGVVVAEEFAEAL 71
BHD_1 pfam10403
Rad4 beta-hairpin domain 1; This short domain is found in the Rad4 protein. This domain binds ...
417-469 6.25e-20

Rad4 beta-hairpin domain 1; This short domain is found in the Rad4 protein. This domain binds to DNA.


Pssm-ID: 463077  Cd Length: 54  Bit Score: 83.36  E-value: 6.25e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 19115556   417 SEGIPRNIQDLKDHPLFVLERHLKKNQAIKTG-KSCGRINTKNGVELVYPRKYV 469
Cdd:pfam10403   1 NEPMPTNIQDFKNHPLYVLERHLKRNEVIYPGaKPVGTFRYKKKGEPVYRRSDV 54
BHD_1 smart01030
Rad4 beta-hairpin domain 1; This short domain is found in the Rad4 protein. This domain binds ...
416-469 6.45e-17

Rad4 beta-hairpin domain 1; This short domain is found in the Rad4 protein. This domain binds to DNA.


Pssm-ID: 214984 [Multi-domain]  Cd Length: 54  Bit Score: 74.95  E-value: 6.45e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 19115556    416 QSEGIPRNIQDLKDHPLFVLERHLKKNQAIKTG-KSCGRINTKNGvELVYPRKYV 469
Cdd:smart01030   1 LNEPIPTSIQDFKNHPLYVLERHLKKNEAIYPKaKPVGTFGYGKG-EPVYLRSDV 54
BHD_2 smart01031
Rad4 beta-hairpin domain 2; This short domain is found in the Rad4 protein. This domain binds ...
472-515 5.24e-13

Rad4 beta-hairpin domain 2; This short domain is found in the Rad4 protein. This domain binds to DNA.


Pssm-ID: 214985 [Multi-domain]  Cd Length: 56  Bit Score: 63.86  E-value: 5.24e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 19115556    472 GFSAEHWYRKGRIIKPGAQPLKHVK------------NGDKVLPLYDEEATQLYTP 515
Cdd:smart01031   1 LKSAEHWLRQGRVVKPGEQPYKVVKrkrkkdripndtGEEEELELYGEWQTELYIP 56
BHD_2 pfam10404
Rad4 beta-hairpin domain 2; This short domain is found in the Rad4 protein. This domain binds ...
474-515 3.23e-09

Rad4 beta-hairpin domain 2; This short domain is found in the Rad4 protein. This domain binds to DNA.


Pssm-ID: 463078 [Multi-domain]  Cd Length: 63  Bit Score: 53.37  E-value: 3.23e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19115556   474 SAEHWYRKGRIIKPGAQPLKHVK------------------NGDKVL-PLYDEEATQLYTP 515
Cdd:pfam10404   2 SAEKWYREGREVKPGEQPLKRVKaravtknrkreeedareeDGEEGGvGLYAEWQTELYIP 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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