|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
138-408 |
6.95e-45 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 160.46 E-value: 6.95e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 138 VLAVGLASSIYLWSAASGKVVQLHdFGATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAW- 216
Cdd:COG2319 93 LASASADGTVRLWDLATGLLLRTL-TGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFs 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 217 -NDNTLTSGGKDEVILHHDLRAPGCCAEmMKVHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFEEHTAAVK 295
Cdd:COG2319 172 pDGKLLASGSDDGTVRLWDLATGKLLRT-LTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVR 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 296 AIGWSPHQRgILASGGGtiDRCLTIHNTLTGRLQNKLDT-GSQVCNMAWSKTSNEIVTthGFAKNQVSLWKYPSLKNIAN 374
Cdd:COG2319 251 SVAFSPDGR-LLASGSA--DGTVRLWDLATGELLRTLTGhSGGVNSVAFSPDGKLLAS--GSDDGTVRLWDLATGKLLRT 325
|
250 260 270
....*....|....*....|....*....|....
gi 19111873 375 LTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKL 408
Cdd:COG2319 326 LTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDL 359
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
135-407 |
1.09e-38 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 140.93 E-value: 1.09e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 135 QSNVLAVGLA-SSIYLWSAASGKVV---QLHDFGatnhVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSER 210
Cdd:cd00200 20 DGKLLATGSGdGTIKVWDLETGELLrtlKGHTGP----VRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 211 VAALAWNDNT--LTSGGKDEVILHHDLRAPGCCAEmMKVHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFE 288
Cdd:cd00200 96 VSSVAFSPDGriLSSSSRDKTIKVWDVETGKCLTT-LRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 289 EHTAAVKAIGWSPHQRGILASGGgtiDRCLTIHNTLTGRLQNKLDT-GSQVCNMAWSKTSNEIVTthGFAKNQVSLWKYP 367
Cdd:cd00200 175 GHTGEVNSVAFSPDGEKLLSSSS---DGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLAS--GSEDGTIRVWDLR 249
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 19111873 368 SLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWK 407
Cdd:cd00200 250 TGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
156-219 |
2.64e-06 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 45.35 E-value: 2.64e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19111873 156 KVVQLHDFGATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAWNDN 219
Cdd:pfam12894 28 RVWTLSPDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWGEN 91
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
157-297 |
7.12e-06 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 48.16 E-value: 7.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 157 VVQLhdfGATNHVTSVLWTGK-GTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAWN--DNTLTSGGKDEVILHH 233
Cdd:PLN00181 526 VVEL---ASRSKLSGICWNSYiKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSsaDPTLLASGSDDGSVKL 602
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19111873 234 DLRAPGCCAEMMKVhEQEICGLQWDRSLGQ-LASGGNDNNLFVWDYRSSR-PLHKFEEHTAAVKAI 297
Cdd:PLN00181 603 WSINQGVSIGTIKT-KANICCVQFPSESGRsLAFGSADHKVYYYDLRNPKlPLCTMIGHSKTVSYV 667
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
368-407 |
3.27e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.76 E-value: 3.27e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 19111873 368 SLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWK 407
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
138-408 |
6.95e-45 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 160.46 E-value: 6.95e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 138 VLAVGLASSIYLWSAASGKVVQLHdFGATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAW- 216
Cdd:COG2319 93 LASASADGTVRLWDLATGLLLRTL-TGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFs 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 217 -NDNTLTSGGKDEVILHHDLRAPGCCAEmMKVHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFEEHTAAVK 295
Cdd:COG2319 172 pDGKLLASGSDDGTVRLWDLATGKLLRT-LTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVR 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 296 AIGWSPHQRgILASGGGtiDRCLTIHNTLTGRLQNKLDT-GSQVCNMAWSKTSNEIVTthGFAKNQVSLWKYPSLKNIAN 374
Cdd:COG2319 251 SVAFSPDGR-LLASGSA--DGTVRLWDLATGELLRTLTGhSGGVNSVAFSPDGKLLAS--GSDDGTVRLWDLATGKLLRT 325
|
250 260 270
....*....|....*....|....*....|....
gi 19111873 375 LTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKL 408
Cdd:COG2319 326 LTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDL 359
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
138-408 |
6.99e-42 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 152.37 E-value: 6.99e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 138 VLAVGLASSIYLWSAASGKVVQ-LHdfGATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAW 216
Cdd:COG2319 135 LASGSADGTVRLWDLATGKLLRtLT--GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAF 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 217 --NDNTLTSGGKDEVILHHDLRAPGCCAEmMKVHEQEICGLQWDRSlGQ-LASGGNDNNLFVWDYRSSRPLHKFEEHTAA 293
Cdd:COG2319 213 spDGKLLASGSADGTVRLWDLATGKLLRT-LTGHSGSVRSVAFSPD-GRlLASGSADGTVRLWDLATGELLRTLTGHSGG 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 294 VKAIGWSPHQRgILASGG--GTIdrclTIHNTLTGRLQNKLD-TGSQVCNMAWSKTSNEIVTthGFAKNQVSLWKYPSLK 370
Cdd:COG2319 291 VNSVAFSPDGK-LLASGSddGTV----RLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLAS--GSDDGTVRLWDLATGE 363
|
250 260 270
....*....|....*....|....*....|....*...
gi 19111873 371 NIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKL 408
Cdd:COG2319 364 LLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDL 401
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
135-407 |
1.09e-38 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 140.93 E-value: 1.09e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 135 QSNVLAVGLA-SSIYLWSAASGKVV---QLHDFGatnhVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSER 210
Cdd:cd00200 20 DGKLLATGSGdGTIKVWDLETGELLrtlKGHTGP----VRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 211 VAALAWNDNT--LTSGGKDEVILHHDLRAPGCCAEmMKVHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFE 288
Cdd:cd00200 96 VSSVAFSPDGriLSSSSRDKTIKVWDVETGKCLTT-LRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 289 EHTAAVKAIGWSPHQRGILASGGgtiDRCLTIHNTLTGRLQNKLDT-GSQVCNMAWSKTSNEIVTthGFAKNQVSLWKYP 367
Cdd:cd00200 175 GHTGEVNSVAFSPDGEKLLSSSS---DGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLAS--GSEDGTIRVWDLR 249
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 19111873 368 SLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWK 407
Cdd:cd00200 250 TGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
138-408 |
1.23e-36 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 138.12 E-value: 1.23e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 138 VLAVGLASSIYLWSAASGKVVQLHDFGATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAW- 216
Cdd:COG2319 50 RLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFs 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 217 -NDNTLTSGGKDEVILHHDLRAPGCCAEmMKVHEQEICGLQWDRSlGQ-LASGGNDNNLFVWDYRSSRPLHKFEEHTAAV 294
Cdd:COG2319 130 pDGKTLASGSADGTVRLWDLATGKLLRT-LTGHSGAVTSVAFSPD-GKlLASGSDDGTVRLWDLATGKLLRTLTGHTGAV 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 295 KAIGWSPHQRgILASGGGtiDRCLTIHNTLTGRLQNKLDT-GSQVCNMAWSKTSNEIVTthGFAKNQVSLWKYPSLKNIA 373
Cdd:COG2319 208 RSVAFSPDGK-LLASGSA--DGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPDGRLLAS--GSADGTVRLWDLATGELLR 282
|
250 260 270
....*....|....*....|....*....|....*
gi 19111873 374 NLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKL 408
Cdd:COG2319 283 TLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDL 317
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
169-414 |
5.76e-33 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 125.53 E-value: 5.76e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 169 VTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAW--NDNTLTSGGKDEVILHHDLRAPGCCAEMmK 246
Cdd:cd00200 12 VTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAAsaDGTYLASGSSDKTIRLWDLETGECVRTL-T 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 247 VHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFEEHTAAVKAIGWSPHQRgILASGGGtiDRCLTIHNTLTG 326
Cdd:cd00200 91 GHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGT-FVASSSQ--DGTIKLWDLRTG 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 327 RLQNKLdTG--SQVCNMAWSKTSNEIVTthGFAKNQVSLWKYPSLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLR 404
Cdd:cd00200 168 KCVATL-TGhtGEVNSVAFSPDGEKLLS--SSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIR 244
|
250
....*....|
gi 19111873 405 FWKLFNKKPK 414
Cdd:cd00200 245 VWDLRTGECV 254
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
131-408 |
1.30e-27 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 113.08 E-value: 1.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 131 LDWGQSNVLAVGLASSIYLWSAASGKVVQLHDFGATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSER 210
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 211 VAALAW--NDNTLTSGGKDEVILHHDLRAPGCCAEMMKvHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFE 288
Cdd:COG2319 81 VLSVAFspDGRLLASASADGTVRLWDLATGLLLRTLTG-HTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 289 EHTAAVKAIGWSPHQRgILASGGGtiDRCLTIHNTLTGRLQNKLD-TGSQVCNMAWSKTSNEIVTthGFAKNQVSLWKYP 367
Cdd:COG2319 160 GHSGAVTSVAFSPDGK-LLASGSD--DGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDGKLLAS--GSADGTVRLWDLA 234
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 19111873 368 SLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKL 408
Cdd:COG2319 235 TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDL 275
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
200-408 |
5.57e-27 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 108.96 E-value: 5.57e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 200 SVRSLKGHSERVAALAWND--NTLTSGGKDEVILHHDLrAPGCCAEMMKVHEQEICGLQWDRSLGQLASGGNDNNLFVWD 277
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPdgKLLATGSGDGTIKVWDL-ETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 278 YRSSRPLHKFEEHTAAVKAIGWSPHQRgILASGGGtiDRCLTIHNTLTGRLQNKLDT-GSQVCNMAWSKTsNEIVTThGF 356
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFSPDGR-ILSSSSR--DKTIKVWDVETGKCLTTLRGhTDWVNSVAFSPD-GTFVAS-SS 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 19111873 357 AKNQVSLWKYPSLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKL 408
Cdd:cd00200 155 QDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDL 206
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
246-414 |
2.78e-13 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 70.06 E-value: 2.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 246 KVHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFEEHTAAVKAIGWSPHQRGILASGGgtiDRCLTIhntlt 325
Cdd:cd00200 6 KGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSS---DKTIRL----- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 326 grlqnkldtgsqvcnmaWSKTSNEIVTThgfaknqvslwkypslknianLTAHTNRVLYLSMSPDGQSIVTGAGDETLRF 405
Cdd:cd00200 78 -----------------WDLETGECVRT---------------------LTGHTSYVSSVAFSPDGRILSSSSRDKTIKV 119
|
....*....
gi 19111873 406 WKLFNKKPK 414
Cdd:cd00200 120 WDVETGKCL 128
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
156-219 |
2.64e-06 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 45.35 E-value: 2.64e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19111873 156 KVVQLHDFGATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAWNDN 219
Cdd:pfam12894 28 RVWTLSPDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWGEN 91
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
157-297 |
7.12e-06 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 48.16 E-value: 7.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 157 VVQLhdfGATNHVTSVLWTGK-GTQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAWN--DNTLTSGGKDEVILHH 233
Cdd:PLN00181 526 VVEL---ASRSKLSGICWNSYiKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSsaDPTLLASGSDDGSVKL 602
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19111873 234 DLRAPGCCAEMMKVhEQEICGLQWDRSLGQ-LASGGNDNNLFVWDYRSSR-PLHKFEEHTAAVKAI 297
Cdd:PLN00181 603 WSINQGVSIGTIKT-KANICCVQFPSESGRsLAFGSADHKVYYYDLRNPKlPLCTMIGHSKTVSYV 667
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
368-407 |
3.27e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.76 E-value: 3.27e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 19111873 368 SLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWK 407
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
251-408 |
4.29e-05 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 45.85 E-value: 4.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 251 EICGLQWDRSL-GQLASGGNDNNLFVWDYRSSRPLHKFEEHTAAVKAIGWSPHQRGILASGG--GTIDRCLTIHNTLTGR 327
Cdd:PLN00181 534 KLSGICWNSYIkSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSADPTLLASGSddGSVKLWSINQGVSIGT 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 328 LQNKldtgSQVCNMAWSKTSNEIVtTHGFAKNQVSlwkYPSLKN----IANLTAHTNRVLYLSMSpDGQSIVTGAGDETL 403
Cdd:PLN00181 614 IKTK----ANICCVQFPSESGRSL-AFGSADHKVY---YYDLRNpklpLCTMIGHSKTVSYVRFV-DSSTLVSSSTDNTL 684
|
....*
gi 19111873 404 RFWKL 408
Cdd:PLN00181 685 KLWDL 689
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
179-293 |
7.82e-05 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 44.88 E-value: 7.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 179 TQLAVGTDSGVIYIWDIES---TKSVRS----LKGHSERVAALAWN---DNTLTSGGKDEVILHHDLRApGCCAEMMKVH 248
Cdd:PTZ00421 89 QKLFTASEDGTIMGWGIPEeglTQNISDpivhLQGHTKKVGIVSFHpsaMNVLASAGADMVVNVWDVER-GKAVEVIKCH 167
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 19111873 249 EQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFEEHTAA 293
Cdd:PTZ00421 168 SDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASA 212
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
336-419 |
1.00e-04 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 43.86 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19111873 336 SQVCNMAWSKTSNEIVTthGFAKNQVSLWKYPSLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKLfnKKPKE 415
Cdd:cd00200 10 GGVTCVAFSPDGKLLAT--GSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL--ETGEC 85
|
....
gi 19111873 416 ESTL 419
Cdd:cd00200 86 VRTL 89
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
370-406 |
1.38e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 38.87 E-value: 1.38e-04
10 20 30
....*....|....*....|....*....|....*..
gi 19111873 370 KNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFW 406
Cdd:pfam00400 2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
238-277 |
3.27e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 38.06 E-value: 3.27e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 19111873 238 PGCCAEMMKVHEQEICGLQWDRSLGQLASGGNDNNLFVWD 277
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
143-197 |
3.63e-04 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 42.59 E-value: 3.63e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19111873 143 LASS-----IYLWSAASGKvvQLHDF-GATNHVTSVLWTGKGTQLAVGTDSGVIYIWDIES 197
Cdd:COG2319 345 LASGsddgtVRLWDLATGE--LLRTLtGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
|