|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
11-335 |
8.89e-24 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 105.38 E-value: 8.89e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 11 TLAWSPRGvndnqALLALGGYTGTegsknsdtlLELWNenPESQKPVGSIDVKTRF-YDLAWekSLDkpmG-VIAGSLED 88
Cdd:COG2319 125 SVAFSPDG-----KTLASGSADGT---------VRLWD--LATGKLLRTLTGHSGAvTSVAF--SPD---GkLLASGSDD 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 89 GGIGFWDPAAilksdeaSASIATYKSENGSILGpLDFNrlqPN--LLASGDNKGDVWVWDIKHPQQPFALPKQnrSSEVH 166
Cdd:COG2319 184 GTVRLWDLAT-------GKLLRTLTGHTGAVRS-VAFS---PDgkLLASGSADGTVRLWDLATGKLLRTLTGH--SGSVR 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 167 VVSWNNKvSHILASGNATEYTTVWDVKLKRQVLNLSylgaagvsAATGAVNSIAWHPNNaTRLATAIDDNRnpiILTWDL 246
Cdd:COG2319 251 SVAFSPD-GRLLASGSADGTVRLWDLATGELLRTLT--------GHSGGVNSVAFSPDG-KLLASGSDDGT---VRLWDL 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 247 RQPTVPQnILTGHQKAALSLSWCPeDPTFLLSSGKDGRAMVWNVETGESLGSFPRSGNWYTKSSWCPsNSNRVAVASLEG 326
Cdd:COG2319 318 ATGKLLR-TLTGHTGAVRSVAFSP-DGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSP-DGRTLASGSADG 394
|
....*....
gi 19112374 327 KVSIFSIQS 335
Cdd:COG2319 395 TVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
81-332 |
1.35e-20 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 93.55 E-value: 1.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 81 VIAGSlEDGGIGFWDPaailksdEASASIATYKSENGSILGpLDFNRLQPNLLASGDNKgDVWVWDIKHPQQPFALPKQN 160
Cdd:cd00200 66 LASGS-SDKTIRLWDL-------ETGECVRTLTGHTSYVSS-VAFSPDGRILSSSSRDK-TIKVWDVETGKCLTTLRGHT 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 161 RSseVHVVSWNnKVSHILASGNATEYTTVWDVKLKRQVLNLSylgaagvsAATGAVNSIAWHPNNAtRLATAIDDNrnpI 240
Cdd:cd00200 136 DW--VNSVAFS-PDGTFVASSSQDGTIKLWDLRTGKCVATLT--------GHTGEVNSVAFSPDGE-KLLSSSSDG---T 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 241 ILTWDLRQPTVPQnILTGHQKAALSLSWCPeDPTFLLSSGKDGRAMVWNVETGESLGSFPRSGNWYTKSSWCPsNSNRVA 320
Cdd:cd00200 201 IKLWDLSTGKCLG-TLRGHENGVNSVAFSP-DGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSP-DGKRLA 277
|
250
....*....|..
gi 19112374 321 VASLEGKVSIFS 332
Cdd:cd00200 278 SGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
80-335 |
4.28e-20 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 94.21 E-value: 4.28e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 80 GVIAGSLEDGGIGFWDPAAilksdeaSASIATYKSENGSILGpLDFNrlqPN--LLASGDNKGDVWVWDIKHPQQPFALP 157
Cdd:COG2319 91 RLLASASADGTVRLWDLAT-------GLLLRTLTGHTGAVRS-VAFS---PDgkTLASGSADGTVRLWDLATGKLLRTLT 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 158 KQnrSSEVHVVSWNNKvSHILASGNATEYTTVWDVKLKRQVLNLSylgaagvsAATGAVNSIAWHPNNaTRLATAIDDNR 237
Cdd:COG2319 160 GH--SGAVTSVAFSPD-GKLLASGSDDGTVRLWDLATGKLLRTLT--------GHTGAVRSVAFSPDG-KLLASGSADGT 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 238 npiILTWDLRQPTVPQnILTGHQKAALSLSWCPeDPTFLLSSGKDGRAMVWNVETGESLGSFPRSGNWYTKSSWCPsNSN 317
Cdd:COG2319 228 ---VRLWDLATGKLLR-TLTGHSGSVRSVAFSP-DGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSP-DGK 301
|
250
....*....|....*...
gi 19112374 318 RVAVASLEGKVSIFSIQS 335
Cdd:COG2319 302 LLASGSDDGTVRLWDLAT 319
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
130-335 |
2.81e-19 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 91.90 E-value: 2.81e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 130 PNLLASGDNKGDVWVWDIKHPQQPFALpkQNRSSEVHVVSWnNKVSHILASGNATEYTTVWDVKLKRQVLNLsylgaagv 209
Cdd:COG2319 90 GRLLASASADGTVRLWDLATGLLLRTL--TGHTGAVRSVAF-SPDGKTLASGSADGTVRLWDLATGKLLRTL-------- 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 210 SAATGAVNSIAWHPNNaTRLATAIDDNRnpiILTWDLRQPTVPQnILTGHQKAALSLSWCPeDPTFLLSSGKDGRAMVWN 289
Cdd:COG2319 159 TGHSGAVTSVAFSPDG-KLLASGSDDGT---VRLWDLATGKLLR-TLTGHTGAVRSVAFSP-DGKLLASGSADGTVRLWD 232
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 19112374 290 VETGESLGSFPRSGNWYTKSSWCPsNSNRVAVASLEGKVSIFSIQS 335
Cdd:COG2319 233 LATGKLLRTLTGHSGSVRSVAFSP-DGRLLASGSADGTVRLWDLAT 277
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
780-1110 |
8.20e-19 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 93.46 E-value: 8.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 780 PGAKEEIQRLTMLLEPHAVPPIHQIKQTGYAPVQPKTSQASSILPTVPRTTSYTSPYATTSSHITPADVHPLPPPSTSTT 859
Cdd:PHA03247 2686 RAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAG 2765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 860 AGWNDAPmlgqlpmrRAAPSMAPVRSPFPGASSAQPaamSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGEtyhPPT 939
Cdd:PHA03247 2766 PPAPAPP--------AAPAAGPPRRLTRPAVASLSE---SRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL---PPP 2831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 940 ASGTRVPPVQQPSHPNPYTP----VAPQSPVAAASRISSSPNMPPSNPYTPiavASSTVNPAHTYKPHggSQIVPPPKQP 1015
Cdd:PHA03247 2832 TSAQPTAPPPPPGPPPPSLPlggsVAPGGDVRRRPPSRSPAAKPAAPARPP---VRRLARPAVSRSTE--SFALPPDQPE 2906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1016 anrvvPLPPTASQrasayEPPTVSVPSPSALSPSVTPQLPPVS-SRLPPVSATRPQiPQPPPVSTA------LPSSSAVS 1088
Cdd:PHA03247 2907 -----RPPQPQAP-----PPPQPQPQPPPPPQPQPPPPPPPRPqPPLAPTTDPAGA-GEPSGAVPQpwlgalVPGRVAVP 2975
|
330 340
....*....|....*....|..
gi 19112374 1089 RPPIATSAGRSSTAASTSAPLT 1110
Cdd:PHA03247 2976 RFRVPQPAPSREAPASSTPPLT 2997
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
810-1147 |
5.20e-18 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 90.77 E-value: 5.20e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 810 APVQPKTsqassilPTVPRTTSyTSPYATTSSHITPADVHPLPPPSTSTTAGWNDAPMLGQLPMR--------------- 874
Cdd:PHA03247 2591 APPQSAR-------PRAPVDDR-GDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPpperprddpapgrvs 2662
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 875 ---------RAAPSMAPVRSPFPGAssAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETYHPPTASGTRV 945
Cdd:PHA03247 2663 rprrarrlgRAAQASSPPQRPRRRA--ARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPA 2740
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 946 PPvqqpshPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLP-- 1023
Cdd:PHA03247 2741 PP------AVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLap 2814
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1024 ----PTASQRASAYEPPTVSVPSPSALSPsvtpqlPPVSSRLPPVSATRPQIP--QPPPVSTALPSSSAVSRPPIATSAG 1097
Cdd:PHA03247 2815 aaalPPAASPAGPLPPPTSAQPTAPPPPP------GPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR 2888
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 19112374 1098 RSSTAASTSAPLTYPAGDRSHIPGNLRPIYEMLNAELQRVSQSLPPQMSR 1147
Cdd:PHA03247 2889 PAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
793-1121 |
6.70e-17 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 86.36 E-value: 6.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 793 LEPHAVPPIHQIKQTGYAPVQPKTSQASSILPTVPRTTSYTSPyattsshITPAdvhPLPPPSTSTTAGWNDAPML-GQL 871
Cdd:pfam03154 206 VPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPP-------LQPM---TQPPPPSQVSPQPLPQPSLhGQM 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 872 PMRRAAPSMAPVRSPFPGASsaQPAAMSRTSSVSTLPPPPPTASmtasapaiasppppkvgetyhPPTASGTRVPPVQQP 951
Cdd:pfam03154 276 PPMPHSLQTGPSHMQHPVPP--QPFPLTPQSSQSQVPPGPSPAA---------------------PGQSQQRIHTPPSQS 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 952 SHPNPYTPVAPQSPVAAASRISSSPnmPPSNPYTPIAVASSTVNPAHTYKPHG---GSQIVPPP--KQPANRVVPLPPTA 1026
Cdd:pfam03154 333 QLQSQQPPREQPLPPAPLSMPHIKP--PPTTPIPQLPNPQSHKHPPHLSGPSPfqmNSNLPPPPalKPLSSLSTHHPPSA 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1027 SQRASAYEPPTVSVPSPSALSPSVT--PQLPPVSSRLPPVSATRPQIPQPP-PVSTALPSSSAVSRPPIATSAGRSSTAA 1103
Cdd:pfam03154 411 HPPPLQLMPQSQQLPPPPAQPPVLTqsQSLPPPAASHPPTSGLHQVPSQSPfPQHPFVPGGPPPITPPSGPPTSTSSAMP 490
|
330
....*....|....*...
gi 19112374 1104 STSAPLTYPAGDRSHIPG 1121
Cdd:pfam03154 491 GIQPPSSASVSSSGPVPA 508
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
795-1098 |
1.94e-16 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 85.20 E-value: 1.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 795 PHAVPP--IHQIKQTGYAPVQPKTSQAssiLPTVPRTTSYTSPYATTSSHITPADVHPLPPpststtagwndAPMlgqlP 872
Cdd:pfam03154 290 QHPVPPqpFPLTPQSSQSQVPPGPSPA---APGQSQQRIHTPPSQSQLQSQQPPREQPLPP-----------APL----S 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 873 MRRAAPsmaPVRSPFPGASSAQ----PAAMSRTSSV---STLPPPP---PTASMTasapaiasppppkvgeTYHPPTAsg 942
Cdd:pfam03154 352 MPHIKP---PPTTPIPQLPNPQshkhPPHLSGPSPFqmnSNLPPPPalkPLSSLS----------------THHPPSA-- 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 943 tRVPPVQQPSHPNPYTPVAPQSPVaaasrISSSPNMPPSNPYTPIAVASSTVNPAHTYKPH----GGSQIVPPPKQPanr 1018
Cdd:pfam03154 411 -HPPPLQLMPQSQQLPPPPAQPPV-----LTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHpfvpGGPPPITPPSGP--- 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1019 vvplPPTASQRASAYEPPTVSVPSPSALSP-SVTPQLPPVSSR-LPPVSATRPQIPQPPPVSTAlPSSSAVSRPPIATSA 1096
Cdd:pfam03154 482 ----PTSTSSAMPGIQPPSSASVSSSGPVPaAVSCPLPPVQIKeEALDEAEEPESPPPPPRSPS-PEPTVVNTPSHASQS 556
|
..
gi 19112374 1097 GR 1098
Cdd:pfam03154 557 AR 558
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
108-353 |
3.31e-16 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 80.46 E-value: 3.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 108 SIATYKSENGSILGpLDFNRlQPNLLASGDNKGDVWVWDIKHPQQPFALpkQNRSSEVHVVSWNNKVSHILASGNATeYT 187
Cdd:cd00200 1 LRRTLKGHTGGVTC-VAFSP-DGKLLATGSGDGTIKVWDLETGELLRTL--KGHTGPVRDVAASADGTYLASGSSDK-TI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 188 TVWDVKLKRQVLNLSylgaagvsAATGAVNSIAWHPNNaTRLATAIDDNRnpIILtWDLRQPTvPQNILTGHQKAALSLS 267
Cdd:cd00200 76 RLWDLETGECVRTLT--------GHTSYVSSVAFSPDG-RILSSSSRDKT--IKV-WDVETGK-CLTTLRGHTDWVNSVA 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 268 WCPeDPTFLLSSGKDGRAMVWNVETGESLGSFPRSGNWYTKSSWCPsNSNRVAVASLEGKVSIFSIQSTNTDKSQEASIK 347
Cdd:cd00200 143 FSP-DGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSP-DGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHEN 220
|
....*.
gi 19112374 348 GATSID 353
Cdd:cd00200 221 GVNSVA 226
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
802-1125 |
3.71e-14 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 77.50 E-value: 3.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 802 HQIKQTGYAPVQPKTSQASSILPTVPRTTSYTSPYATTSSHITPADVHPL--PPPSTSTtagwndaPMLGQLPMRRAAPS 879
Cdd:pfam03154 164 QQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPAtsQPPNQTQ-------STAAPHTLIQQTPT 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 880 MAPVRSPFPgASSAQPAamsrtssvsTLPPPPPTASMTASAPAIASPPPPKVGEtyhpPTASGTRVPPVQQPSHPNPYTP 959
Cdd:pfam03154 237 LHPQRLPSP-HPPLQPM---------TQPPPPSQVSPQPLPQPSLHGQMPPMPH----SLQTGPSHMQHPVPPQPFPLTP 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 960 VAPQSPV------AAASRISSSPNMPPSNPYTPIAVA--SSTVNPAHTYKPHggsqIVPPPKQPanrVVPLPPTASQRas 1031
Cdd:pfam03154 303 QSSQSQVppgpspAAPGQSQQRIHTPPSQSQLQSQQPprEQPLPPAPLSMPH----IKPPPTTP---IPQLPNPQSHK-- 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1032 ayEPPTVSVPSP----------------SALS----PSVTP---QLPPVSSRLPPVSATRPQIPQ----PPPVSTALPSS 1084
Cdd:pfam03154 374 --HPPHLSGPSPfqmnsnlppppalkplSSLSthhpPSAHPpplQLMPQSQQLPPPPAQPPVLTQsqslPPPAASHPPTS 451
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 19112374 1085 S---AVSRPPIATSAGRSSTAASTSAPLTYPAGDRSHIPGNLRP 1125
Cdd:pfam03154 452 GlhqVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMPGIQPP 495
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
884-1125 |
5.99e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.20 E-value: 5.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 884 RSPFPGASSAQPAAMSRTSSVST-------LPPPPPTASMTASAPAIASPPPPKVGETYHP------------------- 937
Cdd:PHA03247 2471 GELFPGAPVYRRPAEARFPFAAGaapdpggGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPrmltwirgleelasddagd 2550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 938 ----------PTASGTRVPPVQ---QPSHPN----------PYTPVAPQSPVA--AASRISSSPNMPPSNPYTPIAVASS 992
Cdd:PHA03247 2551 pppplppaapPAAPDRSVPPPRpapRPSEPAvtsrarrpdaPPQSARPRAPVDdrGDPRGPAPPSPLPPDTHAPDPPPPS 2630
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 993 TvNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPqlPPVSsrlPPVSATRPQIP 1072
Cdd:PHA03247 2631 P-SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAAR--PTVG---SLTSLADPPPP 2704
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 19112374 1073 QPPPVSTALPSSSAVSRPPiATSAGRSSTAASTSAPLTYPAGDRSHIPGNLRP 1125
Cdd:PHA03247 2705 PPTPEPAPHALVSATPLPP-GPAAARQASPALPAAPAPPAVPAGPATPGGPAR 2756
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
795-1115 |
1.96e-12 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 72.13 E-value: 1.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 795 PHAVPPIHQIKQTGYAPVQPkTSQASSILPTVPRT----TSYTSPYATTSSHITPADVHPLPPPStsttagwndaPMLGQ 870
Cdd:PHA03307 127 PPSPAPDLSEMLRPVGSPGP-PPAASPPAAGASPAavasDAASSRQAALPLSSPEETARAPSSPP----------AEPPP 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 871 LPMRRAAPSMAPVRSPFPGASSAQPAAMSRTSSVStlppPPPTASMTASAPAIASPPPPKVGETYHPPTASGTRVPPVQQ 950
Cdd:PHA03307 196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAAD----DAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWE 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 951 PSHPNPYTPVAPQSPVAAASRISS---SPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPlPPTAS 1027
Cdd:PHA03307 272 ASGWNGPSSRPGPASSSSSPRERSpspSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGP-SPSRS 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1028 QRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSSSAVSRPPIATSAGRSSTAASTSA 1107
Cdd:PHA03307 351 PSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARY 430
|
....*...
gi 19112374 1108 PLTYPAGD 1115
Cdd:PHA03307 431 PLLTPSGE 438
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
811-1121 |
1.22e-11 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 69.43 E-value: 1.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 811 PVQPKTSQASSILPTVPRTTSYTSPYATTSSHITPADVHPLPPPSTSTTAGWNDAPMLGQLPMRRAAPSMAPV---RSPF 887
Cdd:PHA03307 75 PGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPpaaSPPA 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 888 PGASSAQPAAMSRTSSVSTLPPPPPTASmTASAPAIASPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVA 967
Cdd:PHA03307 155 AGASPAAVASDAASSRQAALPLSSPEET-ARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 968 AASRISSSP----------NMPPSNPYTPIAVASSTVNPAH---------TYKPHGGSQIVPPPKQPANRVVPLPPTASq 1028
Cdd:PHA03307 234 ASSSDSSSSessgcgwgpeNECPLPRPAPITLPTRIWEASGwngpssrpgPASSSSSPRERSPSPSPSSPGSGPAPSSP- 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1029 RASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSSSAVSRPPIATSAGRSSTAASTSAP 1108
Cdd:PHA03307 313 RASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392
|
330
....*....|...
gi 19112374 1109 LTYPAGDRSHIPG 1121
Cdd:PHA03307 393 AVAGRARRRDATG 405
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
850-1091 |
3.64e-11 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 67.87 E-value: 3.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 850 PLPPPSTSTTAGWNDAPMLGQLPMRRAAPSMAPVRSPFPGASSAQPAAMSRTSSVSTLPP-PPPTASMTASAPAIASppp 928
Cdd:pfam03154 149 PSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPqGSPATSQPPNQTQSTA--- 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 929 pkvgetyhPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPnMPPSNPYTPIAVASSTVNPAHTYKPH-GGSQ 1007
Cdd:pfam03154 226 --------APHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQP-LPQPSLHGQMPPMPHSLQTGPSHMQHpVPPQ 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1008 IVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSAlspsvTPQLPPVSSRLPPVSATRPQIpQPPPVS--TALPSSS 1085
Cdd:pfam03154 297 PFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQL-----QSQQPPREQPLPPAPLSMPHI-KPPPTTpiPQLPNPQ 370
|
....*.
gi 19112374 1086 AVSRPP 1091
Cdd:pfam03154 371 SHKHPP 376
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
807-1117 |
8.31e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 66.48 E-value: 8.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 807 TGYAPVQPKTSQASSilPTVPRTTSYTSPyatTSSHITPADVHPLPPPSTSTTAGWNDAPMLGqlpmrRAAPSMApVRSP 886
Cdd:pfam05109 483 SGASPVTPSPSPRDN--GTESKAPDMTSP---TSAVTTPTPNATSPTPAVTTPTPNATSPTLG-----KTSPTSA-VTTP 551
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 887 FPGASSAQPAAMSRT--SSVSTLPPPPPTASMTASAPAIASPPppkVGETYHPP-----TASGTRVPPVQQPSHPNPYTP 959
Cdd:pfam05109 552 TPNATSPTPAVTTPTpnATIPTLGKTSPTSAVTTPTPNATSPT---VGETSPQAnttnhTLGGTSSTPVVTSPPKNATSA 628
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 960 VAP-QSPVAAASriSSSPNMPPSNPYTPIAVASSTVNPAH-----TYKPHGGSQI--VPPPKQPANRVvplpptaSQRAS 1031
Cdd:pfam05109 629 VTTgQHNITSSS--TSSMSLRPSSISETLSPSTSDNSTSHmplltSAHPTGGENItqVTPASTSTHHV-------STSSP 699
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1032 AYEPPTVSVPS-PSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPpvSTALPSSSAVSRPPIATSAGRSST---AASTSA 1107
Cdd:pfam05109 700 APRPGTTSQASgPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQ--KTAVPTVTSTGGKANSTTGGKHTTghgARTSTE 777
|
330
....*....|
gi 19112374 1108 PLTYPAGDRS 1117
Cdd:pfam05109 778 PTTDYGGDST 787
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
938-1114 |
5.13e-10 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 63.93 E-value: 5.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 938 PTASGTRVPPVQQPSHPNPYTPVApQSPVAAASRISSSPNMPPsnPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQP-- 1015
Cdd:PHA03378 590 PSYAQTPWPVPHPSQTPEPPTTQS-HIPETSAPRQWPMPLRPI--PMRPLRMQPITFNVLVFPTPHQPPQVEITPYKPtw 666
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1016 -ANRVVPLPPTASQRASAYEP---PTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSSSAVSRPP 1091
Cdd:PHA03378 667 tQIGHIPYQPSPTGANTMLPIqwaPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARP 746
|
170 180
....*....|....*....|...
gi 19112374 1092 IATSAGRSSTAASTSAPLTYPAG 1114
Cdd:PHA03378 747 PAAAPGRARPPAAAPGRARPPAA 769
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
776-1118 |
8.22e-10 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 63.53 E-value: 8.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 776 PTEFPGAKEEIQRLTMLLEPHAVPPIHQIKQTGYAP------VQPKTSQASSILPTVPRTTsytspyatTSSHITPADVH 849
Cdd:PHA03377 573 PSTGPRVMATPSTGPRDMAPPSTGPRQQAKCKDGPPasgpheKQPPSSAPRDMAPSVVRMF--------LRERLLEQSTG 644
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 850 PLPPPSTSTTAGwNDAPMLGQLPMRRAAPSMA-----PVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIA 924
Cdd:PHA03377 645 PKPKSFWEMRAG-RDGSGIQQEPSSRRQPATQstpprPSWLPSVFVLPSVDAGRAQPSEESHLSSMSPTQPISHEEQPRY 723
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 925 SPPPPKVGETYHPPTA---------SGTRVPPVQQPSHPNPYTPVAPQSP-----VAAASRISSSPNMPPSNPYTPiavA 990
Cdd:PHA03377 724 EDPDDPLDLSLHPDQApppshqapySGHEEPQAQQAPYPGYWEPRPPQAPylgyqEPQAQGVQVSSYPGYAGPWGL---R 800
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 991 SSTVNPAHTYKPHGGSQIVPPPKQP-ANRVVPLPPT------ASQRASAYEPPTVSVPSPSALSPSVTPQLP----PVSS 1059
Cdd:PHA03377 801 AQHPRYRHSWAYWSQYPGHGHPQGPwAPRPPHLPPQwdgsagHGQDQVSQFPHLQSETGPPRLQLSQVPQLPysqtLVSS 880
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 19112374 1060 RLPPVSATRPQIPQpPPVSTALPSSSAvsrpPIATSAGRSSTAASTSAPLTYPAGDRSH 1118
Cdd:PHA03377 881 SAPSWSSPQPRAPI-RPIPTRFPPPPM----PLQDSMAVGCDSSGTACPSMPFASDYSQ 934
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
797-1078 |
9.56e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.42 E-value: 9.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 797 AVPPIHQIKQTGYAPVQPKTSQASSILPTVPRTTSYTSPYATTSSHITPADVHPLPPPSTSTTAGWNDAPMLGQLPMRRA 876
Cdd:PHA03247 2776 AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGS 2855
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 877 APSMAPV-RSPFPGASSAQPAAMSRTSsVSTLPPPPPtasmtasapaiasppppkvgetyhPPTASGTRVPPVQQPSHPN 955
Cdd:PHA03247 2856 VAPGGDVrRRPPSRSPAAKPAAPARPP-VRRLARPAV------------------------SRSTESFALPPDQPERPPQ 2910
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 956 PYTPVAPQSPvaAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGsqiVPPPKQPAnrVVPLPPTASQRASAYEP 1035
Cdd:PHA03247 2911 PQAPPPPQPQ--PQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGA---VPQPWLGA--LVPGRVAVPRFRVPQPA 2983
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 19112374 1036 PTVSVPSPSALSPSVTPqLPPVSSRLPpvSATRPQIPQPPPVS 1078
Cdd:PHA03247 2984 PSREAPASSTPPLTGHS-LSRVSSWAS--SLALHEETDPPPVS 3023
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
773-1144 |
2.10e-09 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 62.01 E-value: 2.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 773 NLVPTEFPGAKEEIQRLTMLLEP----HAV-PPIHQIKQTGYAPVQPKTSQASSIlPTVPRTTSYTS----PYATTSSHI 843
Cdd:PHA03378 618 TSAPRQWPMPLRPIPMRPLRMQPitfnVLVfPTPHQPPQVEITPYKPTWTQIGHI-PYQPSPTGANTmlpiQWAPGTMQP 696
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 844 TPADVHPLPPPSTSttagwndapmlgqlPMRRAAPSMAPVRSPFPGASsaqPAAMSRTSSVSTlPPPPPTASMTASAPAI 923
Cdd:PHA03378 697 PPRAPTPMRPPAAP--------------PGRAQRPAAATGRARPPAAA---PGRARPPAAAPG-RARPPAAAPGRARPPA 758
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 924 ASPPPPKvgetyhPPTASGTRVPPVQQPSHPnpytPVAPQSPVAAasrisSSPNMPPSNPYTPIAVAsstvnpahtykph 1003
Cdd:PHA03378 759 AAPGRAR------PPAAAPGAPTPQPPPQAP----PAPQQRPRGA-----PTPQPPPQAGPTSMQLM------------- 810
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1004 ggsqivppPKQPANRVVPLPPTASQRASAyeppTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQP----PPVST 1079
Cdd:PHA03378 811 --------PRAAPGQQGPTKQILRQLLTG----GVKRGRPSLKKPAALERQAAAGPTPSPGSGTSDKIVQApvfyPPVLQ 878
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 19112374 1080 --ALPSSSAVSRPPIATSAgrsstaasTSAPLTYPAGDRSHIPGNLRPIYEMLNAELQRVSQSLPPQ 1144
Cdd:PHA03378 879 piQVMRQLGSVRAAAASTV--------TQAPTEYTGERRGVGPMHPTDIPPSKRAKTDAYVESQPPH 937
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
830-1147 |
2.42e-09 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 62.02 E-value: 2.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 830 TSYTSPYATTSSHITPADVHPLP-PPSTSTTAGWNDAPmlgqlPMRRAAPSMAPVRSPFPGASS-AQPAAMSRTSSVSTL 907
Cdd:PRK10263 327 TTATQSWAAPVEPVTQTPPVASVdVPPAQPTVAWQPVP-----GPQTGEPVIAPAPEGYPQQSQyAQPAVQYNEPLQQPV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 908 PPPPPTASmtasAPAIASPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPI 987
Cdd:PRK10263 402 QPQQPYYA----PAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPL 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 988 AVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTAS----QRASAYEPPTVSVPSPSALSPSVTPQLPPVssrLPP 1063
Cdd:PRK10263 478 YQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRArereQLAAWYQPIPEPVKEPEPIKSSLKAPSVAA---VPP 554
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1064 VSatrpqipqppPVSTALPSSSAVSRPPIATSAgrsstAASTSAPLTYPAGDrshipGNLRPiyemlnaelqRVSQSLPP 1143
Cdd:PRK10263 555 VE----------AAAAVSPLASGVKKATLATGA-----AATVAAPVFSLANS-----GGPRP----------QVKEGIGP 604
|
....
gi 19112374 1144 QMSR 1147
Cdd:PRK10263 605 QLPR 608
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
834-1118 |
3.90e-09 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 61.34 E-value: 3.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 834 SPYATTSSHITPADVHPLPPPSTSTTAGWNDAPML--GQLPMRRAAPSMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPP 911
Cdd:PHA03307 21 FPRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVvaGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASP 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 912 PTASMTASAPAIASPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVAS 991
Cdd:PHA03307 101 AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 992 STVNPahtykPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQI 1071
Cdd:PHA03307 181 ETARA-----PSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENEC 255
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 19112374 1072 PQPPPVSTALPSSSAVSRPPIATSAGRSSTAASTSAPLTYPAGDRSH 1118
Cdd:PHA03307 256 PLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSS 302
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
807-1108 |
8.03e-09 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 59.93 E-value: 8.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 807 TGYAPVQPKTSQASSILPTVpRTTSYTSPYATT---SSHITPADVhpLPPPSTSTTAGWNDAPMLGQLPMRRAAPSMAPV 883
Cdd:pfam05109 415 TTHKVIFSKAPESTTTSPTL-NTTGFAAPNTTTglpSSTHVPTNL--TAPASTGPTVSTADVTSPTPAGTTSGASPVTPS 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 884 RSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETyHPPTASGTRVPPVQQPShPNPYTPVAPQ 963
Cdd:pfam05109 492 PSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKT-SPTSAVTTPTPNATSPT-PAVTTPTPNA 569
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 964 S-PVAAASRISSSPNMPPSNPYTPiAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVpS 1042
Cdd:pfam05109 570 TiPTLGKTSPTSAVTTPTPNATSP-TVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSL-R 647
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19112374 1043 PSALSPSVTPQLPPVS-SRLPPVSATRP----QIPQPPPVSTA---LPSSSAVSRPPIATSAGRSSTAASTSAP 1108
Cdd:pfam05109 648 PSSISETLSPSTSDNStSHMPLLTSAHPtggeNITQVTPASTSthhVSTSSPAPRPGTTSQASGPGNSSTSTKP 721
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
876-1115 |
2.06e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 58.73 E-value: 2.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 876 AAPSMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTasapaiasppppkvgetyHPPTASGTRVPPVQQPshpn 955
Cdd:PRK12323 375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAA------------------RAVAAAPARRSPAPEA---- 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 956 pyTPVAPQSPVAAASRISSSPNMPPSNPY--TPIAVASSTVNPAHTYKPhggsqivPPPKQPANRVVPLPPTASQRASAy 1033
Cdd:PRK12323 433 --LAAARQASARGPGGAPAPAPAPAAAPAaaARPAAAGPRPVAAAAAAA-------PARAAPAAAPAPADDDPPPWEEL- 502
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1034 ePPTVSVPSPSALSPSvtpqLPPVSSRLPPVSATRPQIPQPPPVSTAlPSSSAVSRPPIATSAGRSSTAASTSAPLTYPA 1113
Cdd:PRK12323 503 -PPEFASPAPAQPDAA----PAGWVAESIPDPATADPDDAFETLAPA-PAAAPAPRAAAATEPVVAPRPPRASASGLPDM 576
|
..
gi 19112374 1114 GD 1115
Cdd:PRK12323 577 FD 578
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
874-1125 |
2.84e-08 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 58.24 E-value: 2.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 874 RRAAPSMapvrsPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETyhPPTASGTRVPPvqQPSH 953
Cdd:pfam03154 142 RSTSPSI-----PSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATA--GPTPSAPSVPP--QGSP 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 954 PNPYTPVAPQSPVAAASRISSSPNMPPS---NPYTPIAVAS-----STVNPAHTYKP--HGGSQIVPPPKQ--PANRVVP 1021
Cdd:pfam03154 213 ATSQPPNQTQSTAAPHTLIQQTPTLHPQrlpSPHPPLQPMTqppppSQVSPQPLPQPslHGQMPPMPHSLQtgPSHMQHP 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1022 LPP----TASQRASAYEPPTvsvPSPSALSPS-VTPQLPPVSSRLPPVSATRPQiPQPPPvstalPSSSAVSRPPIATSA 1096
Cdd:pfam03154 293 VPPqpfpLTPQSSQSQVPPG---PSPAAPGQSqQRIHTPPSQSQLQSQQPPREQ-PLPPA-----PLSMPHIKPPPTTPI 363
|
250 260
....*....|....*....|....*....
gi 19112374 1097 GRSSTAASTSAPLTYPAGDRSHIPGNLRP 1125
Cdd:pfam03154 364 PQLPNPQSHKHPPHLSGPSPFQMNSNLPP 392
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
937-1121 |
4.58e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 57.55 E-value: 4.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 937 PPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPA 1016
Cdd:PRK07003 387 AAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDER 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1017 NRVVPLPP-TASQRASAYEPPTVSVPSPSALSPSvTPQLPPVSSRLPPVSATRPQIPQPPpvstALPSSSAVSRPPIATS 1095
Cdd:PRK07003 467 DAQPPADSgSASAPASDAPPDAAFEPAPRAAAPS-AATPAAVPDARAPAAASREDAPAAA----APPAPEARPPTPAAAA 541
|
170 180 190
....*....|....*....|....*....|.
gi 19112374 1096 AGRSSTAASTSAPLTYPAG-----DRSHIPG 1121
Cdd:PRK07003 542 PAARAGGAAAALDVLRNAGmrvssDRGARAA 572
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
795-1076 |
4.99e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 57.55 E-value: 4.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 795 PHAVPPIHQIKQTGYAPVQPKTSQASSILPTVPRTTSYTSPYATTSSHITPADvhplPPPSTSTTAGwnDAPMLGQLPMR 874
Cdd:PRK07003 377 AGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAA----PAPPATADRG--DDAADGDAPVP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 875 RAAPSMAPVRSPfPGASSAQPAAMSRTSSVSTLPPPPPTASmtasapaiasppppkvgetyhPPTASGTRVPPVQQPSHP 954
Cdd:PRK07003 451 AKANARASADSR-CDERDAQPPADSGSASAPASDAPPDAAF---------------------EPAPRAAAPSAATPAAVP 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 955 NPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYE 1034
Cdd:PRK07003 509 DARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPA 588
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 19112374 1035 PPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQP----PP 1076
Cdd:PRK07003 589 APRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPwediPP 634
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
932-1118 |
6.06e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 57.30 E-value: 6.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 932 GETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPP 1011
Cdd:PRK07764 596 GGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1012 PKQPAnrVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQ------IPQPP------PVST 1079
Cdd:PRK07764 676 AAPAA--PPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSpaaddpVPLPPepddppDPAG 753
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 19112374 1080 ALPSSSAVSRPPIATSAGRSSTAASTSAP------LTYPAGDRSH 1118
Cdd:PRK07764 754 APAQPPPPPAPAPAAAPAAAPPPSPPSEEeemaedDAPSMDDEDR 798
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
816-1115 |
1.23e-07 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 55.74 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 816 TSQASSILPTVPRTTSYTSPYATTSSHITPADVHPLPP----PSTSTTAGwnDAPMLGQlPMRRAAPSMAPVRSPFPGAS 891
Cdd:pfam17823 116 AAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANasaaPRAAIAAA--SAPHAAS-PAPRTAASSTTAASSTTAAS 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 892 SAQPAAMSrtSSVSTLPPPPPTASMTASAPAIASPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASR 971
Cdd:pfam17823 193 SAPTTAAS--SAPATLTPARGISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTI 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 972 ISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHG-GSQIVPPPKQPANRVVPlPPTASQRASAYEPPTVSVPSPSALS--- 1047
Cdd:pfam17823 271 NMGDPHARRLSPAKHMPSDTMARNPAAPMGAQAqGPIIQVSTDQPVHNTAG-EPTPSPSNTTLEPNTPKSVASTNLAvvt 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1048 --------PSVTPQLPPVSSRLPPVSATRPQI---PQPPPVSTALPSSsavsrPPIATSAGRSSTAASTSA-PLTYPAGD 1115
Cdd:pfam17823 350 ttkaqakePSASPVPVLHTSMIPEVEATSPTTqpsPLLPTQGAAGPGI-----LLAPEQVATEATAGTASAgPTPRSSGD 424
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
967-1091 |
1.87e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 55.49 E-value: 1.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 967 AAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSqivPPPKQPANRVVPlPPTASQRASAYEPPTVSVPSPSAL 1046
Cdd:PRK14951 372 AAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAA---SAPAAPPAAAPP-APVAAPAAAAPAAAPAAAPAAVAL 447
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 19112374 1047 SPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSSSAVSRPP 1091
Cdd:PRK14951 448 APAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
775-1062 |
2.52e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 55.27 E-value: 2.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 775 VPTEFPGAkEEIQRLTMLLEPHAVPPIHQIKQTGYAPVQPKTSQASSILPTVPRT-----------TSYTSPYATTSSHI 843
Cdd:PRK12323 307 VQDDWPEA-DDIRRLAGRFDAQEVQLFYQIANLGRSELALAPDEYAGFTMTLLRMlafrpgqsgggAGPATAAAAPVAQP 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 844 TPADVHPLPPPSTSTTAGWNDAPMLGQLPMRRAAPSMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAI 923
Cdd:PRK12323 386 APAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPA 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 924 ASPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPvaaasrissSPNMPPSNPYTPIAVASSTVNPAHTYKPH 1003
Cdd:PRK12323 466 AAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFA---------SPAPAQPDAAPAGWVAESIPDPATADPDD 536
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 19112374 1004 GGSQIVPPPKQPAnrvVPLPPTASQRASAYEPPTVSVPSpsaLSPSVTPQLPPVSSRLP 1062
Cdd:PRK12323 537 AFETLAPAPAAAP---APRAAAATEPVVAPRPPRASASG---LPDMFDGDWPALAARLP 589
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
973-1118 |
5.34e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 53.95 E-value: 5.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 973 SSSPNMPPSNPYTPIAVASSTVNPAhtykphggsqivPPPKQPANRVVPLPPTASQRASAyEPPTVSVPSPSALSPSVTP 1052
Cdd:PRK14951 368 AAAEAAAPAEKKTPARPEAAAPAAA------------PVAQAAAAPAPAAAPAAAASAPA-APPAAAPPAPVAAPAAAAP 434
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19112374 1053 QLPPvssrlPPVSATRPQIPQPPPVSTALPSSSA--VSRPPIATSAGRSSTAASTSAPLT-YPAGDRSH 1118
Cdd:PRK14951 435 AAAP-----AAAPAAVALAPAPPAQAAPETVAIPvrVAPEPAVASAAPAPAAAPAAARLTpTEEGDVWH 498
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
937-1114 |
6.27e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.17 E-value: 6.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 937 PPTASG-TRVPPVQQPSHPNPytPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASstvNPAHTYKPHGGSQIVPPPKQP 1015
Cdd:PHA03247 269 PETARGaTGPPPPPEAAAPNG--AAAPPDGVWGAALAGAPLALPAPPDPPPPAPAG---DAEEEDDEDGAMEVVSPLPRP 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1016 ANRVvPL-----------PPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSS 1084
Cdd:PHA03247 344 RQHY-PLgfpkrrrptwtPPSSLEDLSAGRHHPKRASLPTRKRRSARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTP 422
|
170 180 190
....*....|....*....|....*....|
gi 19112374 1085 SAVSRPPIATSAGRSSTAASTSAPLTYPAG 1114
Cdd:PHA03247 423 VPASAPPPPATPLPSAEPGSDDGPAPPPER 452
|
|
| SRA1 |
pfam07304 |
Steroid receptor RNA activator (SRA1); This family consists of several hypothetical mammalian ... |
1072-1217 |
8.33e-07 |
|
Steroid receptor RNA activator (SRA1); This family consists of several hypothetical mammalian steroid receptor RNA activator proteins. SRA-RNAs likely to encode stable proteins are widely expressed in breast cancer cell lines. SRA-RNA is a steroid receptor co-activator which acts as a functional RNA and is classified as belonging to the growing family of functional non-coding RNAs.
Pssm-ID: 429397 [Multi-domain] Cd Length: 147 Bit Score: 49.82 E-value: 8.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1072 PQPPPVSTALPsssavsrPPIATSAGRSSTAASTSAPLTYPAGDrshIPGNLRPiyemLNAELQRVSQSLPPQmsrVVHD 1151
Cdd:pfam07304 2 MGPPPPSVAPP-------PPPPGGPGPLPQVEPTDSPVSESEPV---VEDVMSV----LNQALDACRGTVRKQ---VCDD 64
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19112374 1152 TEKRLNMLFDRLNSNVLSKPLTDELLALATSLNAHDYQTASNIQTNIVTTLGDQCEHWIVGVTRLI 1217
Cdd:pfam07304 65 VSKRLRLLEDSWRSGKLSLPVRRRMDTLSQELQSGHWDAADDIHRSLMVDHVTEVSQWMVGVKRLI 130
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
845-1062 |
1.15e-06 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 53.01 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 845 PADVHPLPPPSTSTTAGwNDAPMLGQLPMRRAAPSMA-----PVRSPFPGASSAQPAAMSRTSSVStLPPPPPTASMTAS 919
Cdd:PLN03209 341 PVPTKPVTPEAPSPPIE-EEPPQPKAVVPRPLSPYTAyedlkPPTSPIPTPPSSSPASSKSVDAVA-KPAEPDVVPSPGS 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 920 APAIASPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHT 999
Cdd:PLN03209 419 ASNVPEVEPAQVEAKKTRPLSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLS 498
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19112374 1000 YKPHGGSQIVPPPKQPANRVVPLPPTASQRAS---AYEPPTVSV-------PSPSALSP-SVTPQLPPVSSRLP 1062
Cdd:PLN03209 499 PYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVkvgNSAPPTALAdeqhhaqPKPRPLSPyTMYEDLKPPTSPTP 572
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
884-1108 |
1.92e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 52.48 E-value: 1.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 884 RSPFPGASSAQPAAMSRTSSVSTLPPPP-PTASMTASAPAIASPPPPKVGEtyhPPTASGTRVPPVQqpshPNPYTPVAP 962
Cdd:PHA03307 20 FFPRPPATPGDAADDLLSGSQGQLVSDSaELAAVTVVAGAAACDRFEPPTG---PPPGPGTEAPANE----SRSTPTWSL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 963 QSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKP-HGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPT---- 1037
Cdd:PHA03307 93 STLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPdLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASsrqa 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19112374 1038 -VSVPSPSALSPSVTPQLPPVSSRLPPVSATRPqiPQPPPVSTALPSSSAVSRPPIATSAGRSSTAASTSAP 1108
Cdd:PHA03307 173 aLPLSSPEETARAPSSPPAEPPPSTPPAAASPR--PPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSS 242
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
781-1073 |
2.28e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 51.96 E-value: 2.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 781 GAKEEIQRLTMLLEPHAVPPIHQIKQTGYAPVQPKTSQASSILPTVPRTTSYtSPYATTsshiTP-ADVHPlpppststt 859
Cdd:pfam09770 93 DAIEEEQVRFNRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGY-EKYKEP----EPiPDLQV--------- 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 860 agwnDAPMLGQLPMRRAAPSMAPVRSPFPGASSAQP----------AAMSRTSSVSTLPPPPPTASMTASAPAIASPPPP 929
Cdd:pfam09770 159 ----DASLWGVAPKKAAAPAPAPQPAAQPASLPAPSrkmmsleeveAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQ 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 930 KVGETYHPPTASGTRvpPVQQPSHPNPYTPVA----PQSPvaaaSRISSSPNMPPSNPYTPIAVASSTVNPahtykphgg 1005
Cdd:pfam09770 235 QFPPQIQQQQQPQQQ--PQQPQQHPGQGHPVTilqrPQSP----QPDPAQPSIQPQAQQFHQQPPPVPVQP--------- 299
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19112374 1006 SQIVPPPKQPANRVVPLPPTAsqrasayepptvsVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQ 1073
Cdd:pfam09770 300 TQILQNPNRLSAARVGYPQNP-------------QPGVQPAPAHQAHRQQGSFGRQAPIITHPQQLAQ 354
|
|
| KAR9 |
pfam08580 |
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ... |
820-1112 |
2.32e-06 |
|
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.
Pssm-ID: 430088 [Multi-domain] Cd Length: 684 Bit Score: 51.75 E-value: 2.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 820 SSILPTVPRTTSYTSPyATTSSHITPAdvhpLPPPSTSTTAGWNDAPmlgQLPMRRAAPSmapvrspFPGASSAQPAAMS 899
Cdd:pfam08580 406 SSIFEDKNMHDTEDSP-ATLVANKTPG----SSPPSSVIMTPVNKGS---KTPSSRRGSS-------FDFGSSSERVINS 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 900 RTSSVSTLPPPPPTASMTASAPAIasppppkvgetyhpPTASGTRvpPVQQPSHPNPYTPVAPQSPVAAASRISSSPnmP 979
Cdd:pfam08580 471 KLRRESKLPQIASTLKQTKRPSKI--------------PRASPNH--SGFLSTPSNTATSETPTPALRPPSRPQPPP--P 532
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 980 PSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSS 1059
Cdd:pfam08580 533 GNRPRWNASTNTNDLDVGHNFKPLTLTTPSPTPSRSSRSSSTLPPVSPLSRDKSRSPAPTCRSVSRASRRRASRKPTRIG 612
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 19112374 1060 RLPPvsatRPQIPQPPPVSTA-----LPSSSAVSRPPIATSAGRSSTAASTSAPLTYP 1112
Cdd:pfam08580 613 SPNS----RTSLLDEPPYPKLtlskgLPRTPRNRQSYAGTSPSRSVSVSSGLGPQTRP 666
|
|
| SOBP |
pfam15279 |
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual ... |
954-1143 |
3.04e-06 |
|
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual disability. It carries a zinc-finger of the zf-C2H2 type at the N-terminus, and a highly characteriztic C-terminal PhPhPhPhPhPh motif. The deduced 873-amino acid protein contains an N-terminal nuclear localization signal (NLS), followed by 2 FCS-type zinc finger motifs, a proline-rich region (PR1), a putative RNA-binding motif region, and a C-terminal NLS embedded in a second proline-rich motif. SOBP is expressed in various human tissues, including developing mouse brain at embryonic day 14. In postnatal and adult mouse brain SOBP is expressed in all neurons, with intense staining in the limbic system. Highest expression is in layer V cortical neurons, hippocampus, pyriform cortex, dorsomedial nucleus of thalamus, amygdala, and hypothalamus. Postnatal expression of SOBP in the limbic system corresponds to a time of active synaptogenesis. the family is also referred to as Jackson circler, JXC1. In seven affected siblings from a consanguineous Israeli Arab family with mental retardation, anterior maxillary protrusion, and strabismus mutations were found in this protein.
Pssm-ID: 464609 [Multi-domain] Cd Length: 325 Bit Score: 50.58 E-value: 3.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 954 PNPYTP--VAPQSPVAAASRISSSPNmpPSNPYTP-IAVASSTVNPAHtyKPHGGSQIVPPP-------------KQPAN 1017
Cdd:pfam15279 83 ASPASTrsESVSPGPSSSASPSSSPT--SSNSSKPlISVASSSKLLAP--KPHEPPSLPPPPlppkkgrrhrpglHPPLG 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1018 RVVPLPPTASQRASAYEPPTvSVPSPSALSP------------SVTPQLPPVSSRLPPVSATrPQIPQPPPVSTALPSSS 1085
Cdd:pfam15279 159 RPPGSPPMSMTPRGLLGKPQ-QHPPPSPLPAfmepssmpppflRPPPSIPQPNSPLSNPMLP-GIGPPPKPPRNLGPPSN 236
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19112374 1086 AVSRPPIATSAGRSSTAASTSAPLTYPAGDRSHIP--------GNLRPIYEMLNAELQRVSQSLPP 1143
Cdd:pfam15279 237 PMHRPPFSPHHPPPPPTPPGPPPGLPPPPPRGFTPpfgppfppVNMMPNPPEMNFGLPSLAPLVPP 302
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
867-1126 |
3.96e-06 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 51.08 E-value: 3.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 867 MLGQLPMRRAAPSmAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKvgetyhPPTAsgtrvp 946
Cdd:PLN03209 319 LLAKIPSQRVPPK-ESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPLSPYTAYEDLK------PPTS------ 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 947 pvqqPShPNPYTPVAPQSPVAAASRISSSPNMPPSnPYTPIAVASSTVNPAHTYK-----PHGGSQIVPPPKQPAnrvvP 1021
Cdd:PLN03209 386 ----PI-PTPPSSSPASSKSVDAVAKPAEPDVVPS-PGSASNVPEVEPAQVEAKKtrplsPYARYEDLKPPTSPS----P 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1022 LPPTASQrasayepPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSS--SAVSRPPIATSAGRS 1099
Cdd:PLN03209 456 TAPTGVS-------PSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDDLKPPTSpsPAAPVGKVAPSSTNE 528
|
250 260
....*....|....*....|....*..
gi 19112374 1100 STAASTSAPLTYPAGDRSHIPGNLRPI 1126
Cdd:PLN03209 529 VVKVGNSAPPTALADEQHHAQPKPRPL 555
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
814-1113 |
4.25e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 51.23 E-value: 4.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 814 PKTSQASSILPTVPRTTSYTSPYATTSSHITPADVHPLPPPSTSTTAGWNDAPMlgqlpmRRAAPSMAPV---RSPFPGA 890
Cdd:PTZ00449 511 PEGPEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPA------KEHKPSKIPTlskKPEFPKD 584
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 891 SSAQPAAMSRTSSVSTLPPPPPTAsmtasapaiasPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAAS 970
Cdd:PTZ00449 585 PKHPKDPEEPKKPKRPRSAQRPTR-----------PKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKI 653
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 971 RISSSPNMPPSNPYTP----------IAVAS------STVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPT-ASQRASAY 1033
Cdd:PTZ00449 654 IKSPKPPKSPKPPFDPkfkekfyddyLDAAAksketkTTVVLDESFESILKETLPETPGTPFTTPRPLPPKlPRDEEFPF 733
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1034 EPPTvsvpSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPS---SSAVSRPPIATSAGRSSTAASTSAPLT 1110
Cdd:PTZ00449 734 EPIG----DPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEediHAETGEPDEAMKRPDSPSEHEDKPPGD 809
|
...
gi 19112374 1111 YPA 1113
Cdd:PTZ00449 810 HPS 812
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
1009-1113 |
4.51e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 50.93 E-value: 4.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1009 VPPPKQPANrvvPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQlPPVSSRLPPVSATRPQIPQPPPVSTALPSSSAV- 1087
Cdd:PRK14971 369 ASGGRGPKQ---HIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQ-PSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAp 444
|
90 100 110
....*....|....*....|....*....|....*
gi 19112374 1088 ---------SRPPIATSaGRSSTAASTSAPLTYPA 1113
Cdd:PRK14971 445 qavrpaqfkEEKKIPVS-KVSSLGPSTLRPIQEKA 478
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
864-1088 |
5.77e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.75 E-value: 5.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 864 DAPMLGQLPMRRAAPSMAPVRSPFPGASSAQPA-AMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETYHPPTASG 942
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAAPAAPAApAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 943 TRVPPVQQPSHPNPYTPVAPQSPVAAASRISSspnmpPSNPYTPIAVASSTVNPAHTYKPHGGSqivpPPKQPANRVVPL 1022
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA-----PAPAATPPAGQADDPAAQPPQAAQGAS----APSPAADDPVPL 741
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19112374 1023 PPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSSSAVS 1088
Cdd:PRK07764 742 PPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAME 807
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
810-1150 |
1.11e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.98 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 810 APVQPKTSQASSILPTVPRTTSYTSPYATTSSHITPADVHPLP---PPSTSTTAGWNDAPMLGQLPMRRAAPSMAPVRSP 886
Cdd:PRK07764 389 GGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPapaPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAP 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 887 FPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPP----------KVGET---YHPPTASGTRVPPVQQP-- 951
Cdd:PRK07764 469 APAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATlrerwpeilaAVPKRsrkTWAILLPEATVLGVRGDtl 548
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 952 --SHPNP--------------------------YTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPH 1003
Cdd:PRK07764 549 vlGFSTGglarrfaspgnaevlvtalaeelggdWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPA 628
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1004 GGSQIVPP-PKQPANRVVPLPPTASQRASAYEPPTVSVP--SPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTA 1080
Cdd:PRK07764 629 PAGAAAAPaEASAAPAPGVAAPEHHPKHVAVPDASDGGDgwPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT 708
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1081 LPSSSAVSRPPIATSAGRSSTAASTSAPLTYPAGDRSHIPGNLRPIYEMLNAELQRVSQSLPPQMSRVVH 1150
Cdd:PRK07764 709 PPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSP 778
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
858-1117 |
2.40e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.83 E-value: 2.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 858 TTAGWNDAPMLGQLPMRRAAPSMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETYHP 937
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 938 PTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPP-----------------SNPYTPIAVAS--------- 991
Cdd:PRK07764 466 PAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDaatlrerwpeilaavpkRSRKTWAILLPeatvlgvrg 545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 992 STVNPAHTYKPHGGS----------------------QI---VPPPKQPANRVVPLPPTASQRASAYEPPTvSVPSPSAL 1046
Cdd:PRK07764 546 DTLVLGFSTGGLARRfaspgnaevlvtalaeelggdwQVeavVGPAPGAAGGEGPPAPASSGPPEEAARPA-APAAPAAP 624
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19112374 1047 SPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSSSA---VSRPPIATSAGRSSTAASTSAPLTYPAGDRS 1117
Cdd:PRK07764 625 AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDggdGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
937-1148 |
2.77e-05 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 48.52 E-value: 2.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 937 PPTASGTRVPPVQQPShpnpytPVAPQSPVAAASRISS-SPNMPPSNPYTPiavasSTVNPAHTYKPHGGSQIVPPPKQP 1015
Cdd:PHA03379 409 SEPTYGTPRPPVEKPR------PEVPQSLETATSHGSAqVPEPPPVHDLEP-----GPLHDQHSMAPCPVAQLPPGPLQD 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1016 ANR--VVPLPPTASQRASAYEP-PTVSVPSPSALSPSVTPQLPPVSSRLPPVSAtrpqipQPPPVSTALPSSSAVSRPPI 1092
Cdd:PHA03379 478 LEPgdQLPGVVQDGRPACAPVPaPAGPIVRPWEASLSQVPGVAFAPVMPQPMPV------EPVPVPTVALERPVCPAPPL 551
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19112374 1093 ATSAGRSSTAASTSAPLTY------PAGDRSHIPGNLRPIYEMLNAELQRVSQSL---PPQMSRV 1148
Cdd:PHA03379 552 IAMQGPGETSGIVRVRERWrpapwtPNPPRSPSQMSVRDRLARLRAEAQPYQASVevqPPQLTQV 616
|
|
| PRK13042 |
PRK13042 |
superantigen-like protein SSL4; Reviewed; |
1025-1095 |
3.40e-05 |
|
superantigen-like protein SSL4; Reviewed;
Pssm-ID: 183854 [Multi-domain] Cd Length: 291 Bit Score: 47.32 E-value: 3.40e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19112374 1025 TASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTAlPSSSAVSRPPIATS 1095
Cdd:PRK13042 23 TTTQAANATTPSSTKVEAPQSTPPSTKVEAPQSKPNATTPPSTKVEAPQQTPNATT-PSSTKVETPQSPTT 92
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
999-1115 |
3.70e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 47.94 E-value: 3.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 999 TYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRlPPVSATRPQIPQPP--- 1075
Cdd:PRK07994 358 AFHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETT-SQLLAARQQLQRAQgat 436
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 19112374 1076 PVSTALPSSSAVSRPPIATSAGRSSTAASTSAPLTYPAGD 1115
Cdd:PRK07994 437 KAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKK 476
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
838-1035 |
3.86e-05 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 47.68 E-value: 3.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 838 TTSSHITPADVHPLPPPSTSTTAgwndaPMLGQLPMRRAAPSMAPVRSPFPGASSAQPAAMSRTSSVS---TLPPPPPTA 914
Cdd:PRK12727 57 TARSDTPATAAAPAPAPQAPTKP-----AAPVHAPLKLSANANMSQRQRVASAAEDMIAAMALRQPVSvprQAPAAAPVR 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 915 SMTASAPAIASPPPPKVGETYHPPTASGTRVP-----------PVQQPSHPNPYTPVAPQSPVAAAsrissspnmPPSNP 983
Cdd:PRK12727 132 AASIPSPAAQALAHAAAVRTAPRQEHALSAVPeqlfadflttaPVPRAPVQAPVVAAPAPVPAIAA---------ALAAH 202
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 19112374 984 YTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEP 1035
Cdd:PRK12727 203 AAYAQDDDEQLDDDGFDLDDALPQILPPAALPPIVVAPAAPAALAAVAAAAP 254
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
816-985 |
4.15e-05 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 46.99 E-value: 4.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 816 TSQASSILPTVPRTTSYTSPYATTSSHITPADVHPLPPPSTSTTAgwndAPmlgqlpmrrAAPSMAPVRSPFPG----AS 891
Cdd:PRK11901 87 LSSGNQSSPSAANNTSDGHDASGVKNTAPPQDISAPPISPTPTQA----AP---------PQTPNGQQRIELPGnisdAL 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 892 SAQ-----PAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVgetyHPPTASGTRVPPVQQPSHPNPYTPVAPQSPV 966
Cdd:PRK11901 154 SQQqgqvnAASQNAQGNTSTLPTAPATVAPSKGAKVPATAETHPT----PPQKPATKKPAVNHHKTATVAVPPATSGKPK 229
|
170
....*....|....*....
gi 19112374 967 AAASRISSSPNMPPSNpYT 985
Cdd:PRK11901 230 SGAASARALSSAPASH-YT 247
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1000-1129 |
4.22e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.95 E-value: 4.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1000 YKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVS--SRLPPVSATRPQIPQ---- 1073
Cdd:PRK12323 363 FRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAapARRSPAPEALAAARQasar 442
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19112374 1074 -----PPPVSTALPSSSAVSRPPIATSAGRSSTAASTSAPlTYPAGDRSHIPGNLRPIYEM 1129
Cdd:PRK12323 443 gpggaPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPAR-AAPAAAPAPADDDPPPWEEL 502
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
776-1043 |
4.35e-05 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 47.61 E-value: 4.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 776 PTEFPGAKEEIQRLTMLLEPHA-VPPIH----QIKQTGYAPVQPKTSQASSILPTVPRTTSYTS-PYATTSSHITPADVH 849
Cdd:PLN03209 330 PKESDAADGPKPVPTKPVTPEApSPPIEeeppQPKAVVPRPLSPYTAYEDLKPPTSPIPTPPSSsPASSKSVDAVAKPAE 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 850 PLPPPSTSTTAGWnDAPMLGQLPMRRAAP--------SMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASmtasap 921
Cdd:PLN03209 410 PDVVPSPGSASNV-PEVEPAQVEAKKTRPlspyaryeDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATA------ 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 922 aiasppppkVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASstvnpahtyk 1001
Cdd:PLN03209 483 ---------ATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALAD---------- 543
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 19112374 1002 phGGSQIVPPPKqpanrvvPLPPTasqraSAYE---PPTVSVPSP 1043
Cdd:PLN03209 544 --EQHHAQPKPR-------PLSPY-----TMYEdlkPPTSPTPSP 574
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
211-335 |
5.25e-05 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 47.77 E-value: 5.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 211 AATGAVNSIAWHPNNATRLATAiddNRNPIILTWDL-RQPTVPQniLTGHQKAALSLSWCPEDPTFLLSSGKDGRAMVWN 289
Cdd:PLN00181 530 ASRSKLSGICWNSYIKSQVASS---NFEGVVQVWDVaRSQLVTE--MKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWS 604
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 19112374 290 VETGESLGSFPrsgnwyTKSSWC----PSNSNR-VAVASLEGKVSIFSIQS 335
Cdd:PLN00181 605 INQGVSIGTIK------TKANICcvqfPSESGRsLAFGSADHKVYYYDLRN 649
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1015-1107 |
6.40e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 47.11 E-value: 6.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1015 PANRVVPLPPTASQRASAYEPPTVSVPsPSALSPSVTPQLPPVSSRLPP-VSATRPQIPQPPPVSTALPSSS-------- 1085
Cdd:PRK14950 362 PVPAPQPAKPTAAAPSPVRPTPAPSTR-PKAAAAANIPPKEPVRETATPpPVPPRPVAPPVPHTPESAPKLTraaipvde 440
|
90 100
....*....|....*....|...
gi 19112374 1086 -AVSRPPIATSAGRSSTAASTSA 1107
Cdd:PRK14950 441 kPKYTPPAPPKEEEKALIADGDV 463
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
778-1120 |
6.65e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 47.15 E-value: 6.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 778 EFPGAKEeIQRLTMLLEPHAVPPIHQIKQTGYAPVQPKTSQASSILPTVPRTTSYtSPYATTSShiTPADVHPLPPPSTS 857
Cdd:PRK07003 305 EWPEAAD-LRRFAELLSPEQVQLFYQIATVGRGELGLAPDEYAGFTMTLLRMLAF-EPAVTGGG--APGGGVPARVAGAV 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 858 TTAGWNDAPMLGQlpmrRAAPSMAPVRSPfPGASSAQPAAMSRTSSVSTLPP--PPPTASMTASAPAIASPPPPKVGETY 935
Cdd:PRK07003 381 PAPGARAAAAVGA----SAVPAVTAVTGA-AGAALAPKAAAAAAATRAEAPPaaPAPPATADRGDDAADGDAPVPAKANA 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 936 HPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISsspnmPPSNPYTPIAVASSTVNPAHTYKPHGgsQIVPPPKQP 1015
Cdd:PRK07003 456 RASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPA-----PRAAAPSAATPAAVPDARAPAAASRE--DAPAAAAPP 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1016 ANRVVPLPPTASQrasayePPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSSSAVSRPPIATS 1095
Cdd:PRK07003 529 APEARPPTPAAAA------PAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRAR 602
|
330 340
....*....|....*....|....*
gi 19112374 1096 AGRSSTAASTSAPLTYPAGDRSHIP 1120
Cdd:PRK07003 603 AATGDAPPNGAARAEQAAESRGAPP 627
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
876-1105 |
9.11e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.90 E-value: 9.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 876 AAPSMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASmtasapaiasppppkvGETYHPPTASGTRVPPVQQPSHPN 955
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPA----------------GAAAAPAEASAAPAPGVAAPEHHP 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 956 PYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEP 1035
Cdd:PRK07764 655 KHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPA 734
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1036 PTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTalPSSSAVSRPPIATSAGRSSTAAST 1105
Cdd:PRK07764 735 ADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSP--PSEEEEMAEDDAPSMDDEDRRDAE 802
|
|
| PHA02030 |
PHA02030 |
hypothetical protein |
1004-1093 |
1.00e-04 |
|
hypothetical protein
Pssm-ID: 222843 [Multi-domain] Cd Length: 336 Bit Score: 46.13 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1004 GGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVssrlpPVSATRPQIPQPPPVST-ALP 1082
Cdd:PHA02030 248 GGGEDLIIKPKSKAAGSNLPAVPNVAADAGSAAAPAVPAAAAAVAQAAPSVPQV-----PNVAVLPDVPQVAPVAApAAP 322
|
90
....*....|.
gi 19112374 1083 SSSAVSRPPIA 1093
Cdd:PHA02030 323 EVPAVPVVPAA 333
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
868-1025 |
1.08e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 46.63 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 868 LGQLPMRRAAPSMAPVRS-PFPGASSAQPAAMSRTSSVSTLPPPPPTAsmtasapaiASPPPPKVGETYHPPTASGTRVP 946
Cdd:PRK14951 344 LGLAPDEYAALTMVLLRLlAFKPAAAAEAAAPAEKKTPARPEAAAPAA---------APVAQAAAAPAPAAAPAAAASAP 414
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19112374 947 PVQQPSHPNPytPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPT 1025
Cdd:PRK14951 415 AAPPAAAPPA--PVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
811-1031 |
1.13e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 46.45 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 811 PVQPKTSQASSILPTVPRTTS----YTSPYATTSSHI------TPADVHPLPPPSTSTTAGWNDAPMLGQLPMRRAAPSM 880
Cdd:pfam05109 572 PTLGKTSPTSAVTTPTPNATSptvgETSPQANTTNHTlggtssTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSI 651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 881 APVRSP---------FPGASSAQPA----------AMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGET-----YH 936
Cdd:pfam05109 652 SETLSPstsdnstshMPLLTSAHPTggenitqvtpASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgTP 731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 937 PPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRIS---SSPNMPPSNPYTPIAVASSTVNPAHTY-KPHGGSQIVP-- 1010
Cdd:pfam05109 732 PKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTghgARTSTEPTTDYGGDSTTPRTRYNATTYlPPSTSSKLRPrw 811
|
250 260
....*....|....*....|....*
gi 19112374 1011 ----PPKQPANRVVPLPPTASQRAS 1031
Cdd:pfam05109 812 tftsPPVTTAQATVPVPPTSQPRFS 836
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
938-1114 |
1.48e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 45.97 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 938 PTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASR---------ISSSPNMPPSNPYTPiavasstvnpahTYKPHGGSQI 1008
Cdd:PRK14086 90 PSAGEPAPPPPHARRTSEPELPRPGRRPYEGYGGpraddrppgLPRQDQLPTARPAYP------------AYQQRPEPGA 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1009 VPPPkqPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRP----------QIPQPPPVS 1078
Cdd:PRK14086 158 WPRA--ADDYGWQQQRLGFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPdwdrprrdrtDRPEPPPGA 235
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 19112374 1079 -----TALPSSSAVSRPPIATSAGRSSTAASTSAPLTYPAG 1114
Cdd:PRK14086 236 ghvhrGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPGE 276
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
849-1091 |
1.65e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.08 E-value: 1.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 849 HPL------PPPSTSTTAGWNDAPMlgqlPMRRAAPSMAPVRSPFPGASSAQPA---AMSRTSSVSTLPPPPPTASMTAS 919
Cdd:PHA03247 246 HPLrgdiaaPAPPPVVGEGADRAPE----TARGATGPPPPPEAAAPNGAAAPPDgvwGAALAGAPLALPAPPDPPPPAPA 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 920 APAIASPPPPKVGETYHPptasgtrVPpvqqpsHPNPYTPVA-PQ------SPVAAASRISSSPNMPPSNPyTPIAVASS 992
Cdd:PHA03247 322 GDAEEEDDEDGAMEVVSP-------LP------RPRQHYPLGfPKrrrptwTPPSSLEDLSAGRHHPKRAS-LPTRKRRS 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 993 TVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSvTPQLPPvsSRLPPVSATRPQIP 1072
Cdd:PHA03247 388 ARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDD-GPAPPP--ERQPPAPATEPAPD 464
|
250
....*....|....*....
gi 19112374 1073 QPPPVSTALPSSSAVSRPP 1091
Cdd:PHA03247 465 DPDDATRKALDALRERRPP 483
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
893-1035 |
1.70e-04 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 44.85 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 893 AQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETYHPPTAsgtrVPPVQQPSHPNPYTPVAPQSPVAAAsri 972
Cdd:PHA02682 68 ANSACMQRPSGQSPLAPSPACAAPAPACPACAPAAPAPAVTCPAPAPA----CPPATAPTCPPPAVCPAPARPAPAC--- 140
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 19112374 973 ssspnmPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRvVPLPPTASQRASAYEP 1035
Cdd:PHA02682 141 ------PPSTRQCPPAPPLPTPKPAPAAKPIFLHNQLPPPDYPAAS-CPTIETAPAASPVLEP 196
|
|
| KLF10_11_N |
cd21974 |
N-terminal domain of Kruppel-like factor (KLF) 10, KLF11, and similar proteins; This subfamily ... |
950-1084 |
1.83e-04 |
|
N-terminal domain of Kruppel-like factor (KLF) 10, KLF11, and similar proteins; This subfamily is composed of Kruppel-like factor or Krueppel-like factor (KLF) 10, KLF11, and similar proteins. KLF10 was first identified in human osteoblasts and plays a role in mediating estrogen (E2) signaling in bone and skeletal homeostasis and a regulatory role in tumor formation and metastasis. KLF11 is involved in cell growth, apoptosis, cellular inflammation and differentiation, endometriosis, and cholesterol, prostaglandin, neurotransmitter, fat, and sugar metabolism. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved a-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF10/11 belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF10, KLF11, and similar proteins.
Pssm-ID: 409243 [Multi-domain] Cd Length: 229 Bit Score: 44.54 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 950 QPSHPNPYTPV--------APQSPVAAASriSSSPNMPPsnPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVvp 1021
Cdd:cd21974 24 RLRKPRPLTPSsdssdeddAPESPKDFHS--LSSLCMTP--PYSPPFFEASHSPSVASLHPPSAASSQPPPEPESSEP-- 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1022 lPPTASQRASAyepptVSV-----PSPSALSPSVTPQLPPVSSRLPPVSA--TRPQIPQPPPVSTALPSS 1084
Cdd:cd21974 98 -PAASPQRAQA-----TSVirhtaDPVPVSPPPVLCQMLPVSSSSGVIVAflKAPQQPSPQPQKPALPQP 161
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
806-1136 |
2.03e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 45.85 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 806 QTGYAPVQPKTSQAS----SILPTVPRTTSYTSPYATTSSH-ITPADVHPLPPPSTSTTAGWNDAPMlgQLPMRRAAPSM 880
Cdd:PRK10263 331 QSWAAPVEPVTQTPPvasvDVPPAQPTVAWQPVPGPQTGEPvIAPAPEGYPQQSQYAQPAVQYNEPL--QQPVQPQQPYY 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 881 APVRSPFPgaSSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETYHPPTAsgTRVPPVQQPSHPNPYTPV 960
Cdd:PRK10263 409 APAAEQPA--QQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQ--TYQQPAAQEPLYQQPQPV 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 961 APQSPVAAASRISSS-PNMPPSNPYTPIAV--ASSTVNPAHTYKPhggsqiVPppkQPANRVVPLPPTASQRASAYEPPT 1037
Cdd:PRK10263 485 EQQPVVEPEPVVEETkPARPPLYYFEEVEEkrAREREQLAAWYQP------IP---EPVKEPEPIKSSLKAPSVAAVPPV 555
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1038 VSVPSPSALSPSV---TPQLPPVSSRLPPV------SATRPQI-----PQ-PPPVSTALPSSSAVSRPPIATSAGR-SST 1101
Cdd:PRK10263 556 EAAAAVSPLASGVkkaTLATGAAATVAAPVfslansGGPRPQVkegigPQlPRPKRIRVPTRRELASYGIKLPSQRaAEE 635
|
330 340 350
....*....|....*....|....*....|....*
gi 19112374 1102 AASTSAPLTYPAGDRShipgNLRPIYEMLNAELQR 1136
Cdd:PRK10263 636 KAREAQRNQYDSGDQY----NDDEIDAMQQDELAR 666
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
772-983 |
2.18e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.64 E-value: 2.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 772 LNLVPTEFPGakeeiqrLTM-LLEPHAVPPIHQIKQTG-----YAPVQPKTSQASSILPTVPRTTSYTSPYA----TTSS 841
Cdd:PRK12323 343 LALAPDEYAG-------FTMtLLRMLAFRPGQSGGGAGpataaAAPVAQPAPAAAAPAAAAPAPAAPPAAPAaapaAAAA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 842 HITPADVHPLPPPSTSTTAGWNDAPMLGQLPMRRAAPSMAPVrspfPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAP 921
Cdd:PRK12323 416 ARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAA----PAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19112374 922 AI-------------ASPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNP 983
Cdd:PRK12323 492 ADddpppweelppefASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPP 566
|
|
| Gag_spuma |
pfam03276 |
Spumavirus gag protein; |
937-1113 |
2.43e-04 |
|
Spumavirus gag protein;
Pssm-ID: 460872 [Multi-domain] Cd Length: 614 Bit Score: 45.51 E-value: 2.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 937 PPTASGTRVPPVqqPSHPNPYTPvAPQSPVAAasriSSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPa 1016
Cdd:pfam03276 187 PPGASFSGLPSL--PAIGGIHLP-AIPGIHAR----APPGNIARSLGDDIMPSLGDAGMPQPRFAFHPGNPFAEAEGHP- 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1017 nrvvPLPPTASQRASAYEPPTVSVPSPSALS---PSVTPQLPPVSSrLPPVSATRPQIPQPPPVSTALPSSSAVSRPPIa 1093
Cdd:pfam03276 259 ----FAEAEGERPRDIPRAPRIDAPSAPAIPaiqPIAPPMIPPIGA-PIPIPHGASIPGEHIRNPREEPIRLGREAPAI- 332
|
170 180
....*....|....*....|
gi 19112374 1094 tsAGRSSTAASTSAPLTYPA 1113
Cdd:pfam03276 333 --DGRFAPAIDDLFCRIINA 350
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
930-1112 |
3.00e-04 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 45.05 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 930 KVGETY------------HPPTASGTRVPPVQQ-------PSHPNPYTPVAPQSP------VAAASRISSSPNMPPSNPY 984
Cdd:PHA03379 426 EVPQSLetatshgsaqvpEPPPVHDLEPGPLHDqhsmapcPVAQLPPGPLQDLEPgdqlpgVVQDGRPACAPVPAPAGPI 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 985 TPIAVASSTVNPAHTYKPHGgsqivppPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLppvSSRLPPV 1064
Cdd:PHA03379 506 VRPWEASLSQVPGVAFAPVM-------PQPMPVEPVPVPTVALERPVCPAPPLIAMQGPGETSGIVRVRE---RWRPAPW 575
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 19112374 1065 SATRPQIPQPPPVSTALPSSSAVSRPPIATSAGRSS--TAASTSAPLTYP 1112
Cdd:PHA03379 576 TPNPPRSPSQMSVRDRLARLRAEAQPYQASVEVQPPqlTQVSPQQPMEYP 625
|
|
| KLF10_N |
cd21572 |
N-terminal domain of Kruppel-like factor 10; Kruppel-like factor 10 (KLF10; also known as ... |
933-1118 |
3.15e-04 |
|
N-terminal domain of Kruppel-like factor 10; Kruppel-like factor 10 (KLF10; also known as Krueppel-like factor 10; early growth response(EGR)-alpha/EGRA; TGFbeta inducible early gene-1/TIEG1) is a protein that in humans is encoded by the KLF10 gene. KLF10 was first identified in human osteoblasts and plays a role in mediating estrogen (E2) signaling in bone and skeletal homeostasis and a regulatory role in tumor formation and metastasis. It may also play a role in adipocyte differentiation and adipose tissue function. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved a-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF10 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF10.
Pssm-ID: 409241 [Multi-domain] Cd Length: 245 Bit Score: 43.82 E-value: 3.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 933 ETYHPPTASGTRVPPVQQP--SHPNPYTPVAPQSPVA-------------AASRISSSPNMPPSNPYTPIAVASSTVNpa 997
Cdd:cd21572 68 EATHPPSAATLHPPAAQPPeeQHLSAETAASQQRFQCtsvirhtadaqpcSCSSCPSSPSVVPSVPAGVAGVSPVPVY-- 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 998 htykphggSQIVPppkqpanrVVPLPPTASQrasayeppTVSVPSPSALSPSVTPQLPPVSSRLP--PVSATRPQ-IPQP 1074
Cdd:cd21572 146 --------CQILP--------VSSSSTTVVA--------AQAPLPQPQQQAASPAQVFLMGGQVPkgPVMFLVPQpVVPT 201
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 19112374 1075 PPVSTALPSSSAVSRPPIATSAGRSSTAASTSAPLTYPAGDRSH 1118
Cdd:cd21572 202 LYVQPTLVTPGGTKLAAIAPAPGHTPSEQRKSPPQPEVSRVRSH 245
|
|
| Cornifin |
pfam02389 |
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small ... |
948-1083 |
3.79e-04 |
|
Cornifin (SPRR) family; SPRR genes (formerly SPR) encode a novel class of polypeptides (small proline rich proteins) that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. The most characteriztic feature of the SPRR gene family resides in the structure of the central segments of the encoded polypeptides that are built up from tandemly repeated units of either eight (SPRR1 and SPRR3) or nine (SPRR2) amino acids with the general consensus XKXPEPXX where X is any amino acid. In order to avoid bacterial contamination due to the high polar-nature of the HMM the threshold has been set very high.
Pssm-ID: 280537 [Multi-domain] Cd Length: 135 Bit Score: 41.96 E-value: 3.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 948 VQQPSHPNPYTPVAPQSPVAAASRISSspnmpPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPAnrvVPLP--PT 1025
Cdd:pfam02389 5 VKQPCQPPPQEPCVPTTKEPCHSKVPE-----PCNPKVPEPCCPKVPEPCCPKVPEPCCPKVPEPCCPK---VPEPcyPK 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 19112374 1026 ASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSsrlpPVSAtRPQIPQPPPvSTALPS 1083
Cdd:pfam02389 77 VPEPCSPKVPEPCHPKAPEPCHPKVPEPCYPKA----PEPC-QPKVPEPCP-STVTPG 128
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
938-1108 |
4.13e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.48 E-value: 4.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 938 PTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPytpiAVASSTVNPAHtykphggsqiVPPPKQPAn 1017
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAP----AAAAAARAVAA----------APARRSPA- 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1018 rvvPLPPTASQRASAYEPPTVSVPSPSAlspsvtpqlPPVssrlpPVSATRPQIPQPPPvstalpsssavsRPPIATSAG 1097
Cdd:PRK12323 430 ---PEALAAARQASARGPGGAPAPAPAP---------AAA-----PAAAARPAAAGPRP------------VAAAAAAAP 480
|
170
....*....|.
gi 19112374 1098 RSSTAASTSAP 1108
Cdd:PRK12323 481 ARAAPAAAPAP 491
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
951-1126 |
4.59e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 4.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 951 PSHPNPYTPV--APQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTA-- 1026
Cdd:PHA03307 19 EFFPRPPATPgdAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLApa 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1027 --------SQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVS-----TALPSSSAVSRP-PI 1092
Cdd:PHA03307 99 sparegspTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASpaavaSDAASSRQAALPlSS 178
|
170 180 190
....*....|....*....|....*....|....
gi 19112374 1093 ATSAGRSSTAASTSAPLTYPAGDRSHIPGNLRPI 1126
Cdd:PHA03307 179 PEETARAPSSPPAEPPPSTPPAAASPRPPRRSSP 212
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
178-335 |
6.25e-04 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 43.75 E-value: 6.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 178 LASGNATEYTTVWDVKLKRQVLNLSYLGAAGVSAATGAVNSIAWHPNNATRLATAIDDNRnpiilTWDLRQPTVPQNILT 257
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTL-----LLLDAAAGALLATLL 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19112374 258 GHQKAALSLSWCPeDPTFLLSSGKDGRAMVWNVETGESLGSFPRSGNWYTKSSWCPsNSNRVAVASLEGKVSIFSIQS 335
Cdd:COG2319 76 GHTAAVLSVAFSP-DGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSP-DGKTLASGSADGTVRLWDLAT 151
|
|
| half-pint |
TIGR01645 |
poly-U binding splicing factor, half-pint family; The proteins represented by this model ... |
930-1079 |
6.53e-04 |
|
poly-U binding splicing factor, half-pint family; The proteins represented by this model contain three RNA recognition motifs (rrm: pfam00076) and have been characterized as poly-pyrimidine tract binding proteins associated with RNA splicing factors. In the case of PUF60 (GP|6176532), in complex with p54, and in the presence of U2AF, facilitates association of U2 snRNP with pre-mRNA.
Pssm-ID: 130706 [Multi-domain] Cd Length: 612 Bit Score: 43.91 E-value: 6.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 930 KVGETYHPPTasgtrvpPVQQPSHPNPYTPVAPQSPVAAASRI--------SSSPNMPPSNPYTPIAVASSTVnpahtyk 1001
Cdd:TIGR01645 277 RVGKCVTPPD-------ALLQPATVSAIPAAAAVAAAAATAKImaaeavagAAVLGPRAQSPATPSSSLPTDI------- 342
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19112374 1002 phGGSQIVPPPKQPANRVVPLPPTAsqrASAYEPPTVSVPSPsalspsVTPQLPPVSSRLPPVSATRPQIPQPPPVST 1079
Cdd:TIGR01645 343 --GNKAVVSSAKKEAEEVPPLPQAA---PAVVKPGPMEIPTP------VPPPGLAIPSLVAPPGLVAPTEINPSFLAS 409
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
252-289 |
7.72e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 38.06 E-value: 7.72e-04
10 20 30
....*....|....*....|....*....|....*...
gi 19112374 252 PQNILTGHQKAALSLSWCPeDPTFLLSSGKDGRAMVWN 289
Cdd:smart00320 4 LLKTLKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
252-289 |
8.38e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 38.10 E-value: 8.38e-04
10 20 30
....*....|....*....|....*....|....*...
gi 19112374 252 PQNILTGHQKAALSLSWCPeDPTFLLSSGKDGRAMVWN 289
Cdd:pfam00400 3 LLKTLEGHTGSVTSLAFSP-DGKLLASGSDDGTVKVWD 39
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1002-1150 |
8.43e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 8.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1002 PHGGSQIVPPPKQPANRvvPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTAL 1081
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAA--AAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPS 463
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19112374 1082 PSSSAVSRPPIATSAGRSSTAASTSAPLTYPAGDRSHIPGNLRPIYEMLNAELQRVSQSLpPQMSRVVH 1150
Cdd:PRK07764 464 AQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPEILAAV-PKRSRKTW 531
|
|
| SP5_N |
cd22541 |
N-terminal domain of transcription factor Specificity Protein (SP) 5; Specificity Proteins ... |
952-1068 |
8.96e-04 |
|
N-terminal domain of transcription factor Specificity Protein (SP) 5; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. There are many SPs in vertebrates (9 SPs in humans and mice, 7 SPs in the chicken, and 11 SPs in teleost fish), but arthropods only have 3 SPs. All of them contain clade SP5, which plays a potential role in human cancers and was found in several human tumors including hepatocellular carcinoma, gastric cancer, and colon cancer. Leukemia inhibitor factor/Stat3 and Wnt/beta-catenin signaling pathways converge on SP5 to promote mouse embryonic stem cell self-renewal. SP5 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. This model represents the N-terminal domain of SP5.
Pssm-ID: 412096 [Multi-domain] Cd Length: 143 Bit Score: 41.01 E-value: 8.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 952 SHPNPYTPVA--PQSPVAAASRISSSPNMPPSNPYTPiavASSTVNPAHTYKPHGGSQIVPPPkqpaNRVVPLPPTASQR 1029
Cdd:cd22541 3 PHELPLTPPAepSFHQSLAYSFELSPVKMLPTPAPAP---AASAPPHPSPVSSPTQQPQQLPP----NPADDIPWWSIQQ 75
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 19112374 1030 ASAYEPPTVSVP---SPSALSPSVTPQLPPVSSRLPPVSATR 1068
Cdd:cd22541 76 SNPAHPPSTSTPlghPTFAGYQPQIAALLQTKSPAASLSTTR 117
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
986-1096 |
9.77e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 43.32 E-value: 9.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 986 PIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVS 1065
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
|
90 100 110
....*....|....*....|....*....|.
gi 19112374 1066 ATRPQIPQPPPVSTALPSSSAVSRPPIATSA 1096
Cdd:PRK07994 441 SEPAAASRARPVNSALERLASVRPAPSALEK 471
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
797-986 |
1.04e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.44 E-value: 1.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 797 AVPPIHQIKQTGYAPVQPKTSQAssilpTVPRTTSYTSPYATTSSHITPADVHPLPPPSTSTTAGWNDAPMLGQLPMRRA 876
Cdd:PRK07764 598 EGPPAPASSGPPEEAARPAAPAA-----PAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAK 672
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 877 APSMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPppkVGETYHPPTASGTRVPPVQQPSHPNP 956
Cdd:PRK07764 673 AGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQ---AAQGASAPSPAADDPVPLPPEPDDPP 749
|
170 180 190
....*....|....*....|....*....|
gi 19112374 957 YTPVAPQSPVAAASRISSSPNMPPSNPYTP 986
Cdd:PRK07764 750 DPAGAPAQPPPPPAPAPAAAPAAAPPPSPP 779
|
|
| Amelogenin |
smart00818 |
Amelogenins, cell adhesion proteins, play a role in the biomineralisation of teeth; They seem ... |
986-1076 |
1.32e-03 |
|
Amelogenins, cell adhesion proteins, play a role in the biomineralisation of teeth; They seem to regulate formation of crystallites during the secretory stage of tooth enamel development and are thought to play a major role in the structural organisation and mineralisation of developing enamel. The extracellular matrix of the developing enamel comprises two major classes of protein: the hydrophobic amelogenins and the acidic enamelins. Circular dichroism studies of porcine amelogenin have shown that the protein consists of 3 discrete folding units: the N-terminal region appears to contain beta-strand structures, while the C-terminal region displays characteristics of a random coil conformation. Subsequent studies on the bovine protein have indicated the amelogenin structure to contain a repetitive beta-turn segment and a "beta-spiral" between Gln112 and Leu138, which sequester a (Pro, Leu, Gln) rich region. The beta-spiral offers a probable site for interactions with Ca2+ ions. Muatations in the human amelogenin gene (AMGX) cause X-linked hypoplastic amelogenesis imperfecta, a disease characterised by defective enamel. A 9bp deletion in exon 2 of AMGX results in the loss of codons for Ile5, Leu6, Phe7 and Ala8, and replacement by a new threonine codon, disrupting the 16-residue (Met1-Ala16) amelogenin signal peptide.
Pssm-ID: 197891 [Multi-domain] Cd Length: 165 Bit Score: 40.93 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 986 PIAVASSTVNPAHTYKPHGGSQIVPP--PKQPANRVVPLPP----TASQRASAYEPPTVSVPS-PSALSPsvtPQLPPVS 1058
Cdd:smart00818 38 QIIPVSQQHPPTHTLQPHHHIPVLPAqqPVVPQQPLMPVPGqhsmTPTQHHQPNLPQPAQQPFqPQPLQP---PQPQQPM 114
|
90
....*....|....*...
gi 19112374 1059 SRLPPVSATRPQIPQPPP 1076
Cdd:smart00818 115 QPQPPVHPIPPLPPQPPL 132
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1023-1147 |
1.40e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1023 PPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVssrlPPVSATRPQiPQPPPVSTALPSSSAVSRPPIATSAGRSSTA 1102
Cdd:PRK14951 371 EAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAA----APAAAASAP-AAPPAAAPPAPVAAPAAAAPAAAPAAAPAAV 445
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 19112374 1103 ASTSAPLTYPAGDRSHIPGNLRPIYEMLNAELQRVSQSLPPQMSR 1147
Cdd:PRK14951 446 ALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
876-1070 |
1.83e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.55 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 876 AAPSMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPpkvgetyhPPTASGTRVPPVQQPSHpn 955
Cdd:PRK07994 366 PEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPET--------TSQLLAARQQLQRAQGA-- 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 956 pyTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTvnpahtykphggsqivPPPKQPANRVVPLPPTasqrasayEP 1035
Cdd:PRK07994 436 --TKAKKSEPAAASRARPVNSALERLASVRPAPSALEK----------------APAKKEAYRWKATNPV--------EV 489
|
170 180 190
....*....|....*....|....*....|....*.
gi 19112374 1036 PTVSVPSPSALSPSVTPQ-LPPVSSRLPPVSATRPQ 1070
Cdd:PRK07994 490 KKEPVATPKALKKALEHEkTPELAAKLAAEAIERDP 525
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
819-1043 |
1.87e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 42.39 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 819 ASSILPTVPRTTSYTSPYATTSSHITPAdVHPLPPPSTSTTAgwndAPMlgQLPMRRAAPSMAPVRSPFPGASSAQPAAM 898
Cdd:PRK08691 364 ASCDANAVIENTELQSPSAQTAEKETAA-KKPQPRPEAETAQ----TPV--QTASAAAMPSEGKTAGPVSNQENNDVPPW 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 899 SRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETYHPPTASGTRVPPVQQPShPNPyTPVAPQSPVAAASRISSSPNM 978
Cdd:PRK08691 437 EDAPDEAQTAAGTAQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVPS-ENP-IQATPNDEAVETETFAHEAPA 514
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19112374 979 PPSNPYTPiavasstvnPAHTYKPHGGSQIVPPP---KQPANRVVPLPPTASQRASAYEPPTVSVPSP 1043
Cdd:PRK08691 515 EPFYGYGF---------PDNDCPPEDGAEIPPPDwehAAPADTAGGGADEEAEAGGIGGNNTPSAPPP 573
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
776-1109 |
2.02e-03 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 42.35 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 776 PTEFPG-AKEEIQRLTMLLEPHAVPPIHQIKqtgyaPVQPKTSQASSILPtvprttSYTSPYATTSSHITPADVHPLPPP 854
Cdd:PHA03379 513 LSQVPGvAFAPVMPQPMPVEPVPVPTVALER-----PVCPAPPLIAMQGP------GETSGIVRVRERWRPAPWTPNPPR 581
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 855 STS------------TTAGWNDAPMLGQLPMRRAAPSMAPVRSP-------FPGASSAQPAAMSRTSSVSTLPPPPPTAS 915
Cdd:PHA03379 582 SPSqmsvrdrlarlrAEAQPYQASVEVQPPQLTQVSPQQPMEYPlepeqqmFPGSPFSQVADVMRAGGVPAMQPQYFDLP 661
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 916 MTASAPaiasppppkVGETYHPPTASGTRVPPVqqPSHPNPYTPVAPQSPVA----AASRISSSPNMPPSNP---YTPIA 988
Cdd:PHA03379 662 LQQPIS---------QGAPLAPLRASMGPVPPV--PATQPQYFDIPLTEPINqgasAAHFLPQQPMEGPLVPerwMFQGA 730
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 989 VASSTVNPAHTYKPHGGSQIVPP--PKQPANRVVPLPPTASQRASAYEPPTVSVPSPSAlspSVTP-QLPPVssRLPPVS 1065
Cdd:PHA03379 731 TLSQSVRPGVAQSQYFDLPLTQPinHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGT---DVVQhQLDAL--GYVLHV 805
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 19112374 1066 ATRPQIPQPPPVSTALPSSSAVSRPPIATSAGRSSTAASTSAPL 1109
Cdd:PHA03379 806 LNHPGVPVSPAVNQYHVSQAAFGLPIDEDESGEGSDTSEPCEAL 849
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
214-293 |
2.63e-03 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 41.80 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 214 GAVNSIAWHPNNATRLATAIDDNRnpiILTWDLRQPTVPQNI------LTGHQKAALSLSWCPEDPTFLLSSGKDGRAMV 287
Cdd:PTZ00421 76 GPIIDVAFNPFDPQKLFTASEDGT---IMGWGIPEEGLTQNIsdpivhLQGHTKKVGIVSFHPSAMNVLASAGADMVVNV 152
|
....*.
gi 19112374 288 WNVETG 293
Cdd:PTZ00421 153 WDVERG 158
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
941-1106 |
3.62e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 41.51 E-value: 3.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 941 SGTRVPPVQQPshPNPYTPVAPQSPVAAASRISSSPNMPPSNPytpIAVASSTVNPAHTYKphggsqivpppkQPANRVV 1020
Cdd:PRK12727 60 SDTPATAAAPA--PAPQAPTKPAAPVHAPLKLSANANMSQRQR---VASAAEDMIAAMALR------------QPVSVPR 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1021 PLPPTASQRASAYEPPTVSVPSPSA---LSPSVTPQLPPVSSRLPPVSATRPQIPQPppvstALPSSSAVSRPPIATSAG 1097
Cdd:PRK12727 123 QAPAAAPVRAASIPSPAAQALAHAAavrTAPRQEHALSAVPEQLFADFLTTAPVPRA-----PVQAPVVAAPAPVPAIAA 197
|
....*....
gi 19112374 1098 RSSTAASTS 1106
Cdd:PRK12727 198 ALAAHAAYA 206
|
|
| PHA03201 |
PHA03201 |
uracil DNA glycosylase; Provisional |
1013-1144 |
3.74e-03 |
|
uracil DNA glycosylase; Provisional
Pssm-ID: 165468 Cd Length: 318 Bit Score: 41.03 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1013 KQPANRVVPLPPTASqrasayePPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATrpqipQPPPVSTALP---------S 1083
Cdd:PHA03201 2 KRARSRSPSPPRRPS-------PPRPTPPRSPDASPEETPPSPPGPGAEPPPGRA-----AGPAAPRRRPrgcpagvtfS 69
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19112374 1084 SSAVSRPPIatsaGRSSTAASTSAPLTYPAGDRSHIPGNL-RPIYE---------MLNAELQRVSQS---LPPQ 1144
Cdd:PHA03201 70 SSAPPRPPL----GLDDAPAATPPPLDWTEFRRRFLVGDAwRPLLEpelanpltaRLMAEYERRCRTeevLPPR 139
|
|
| SP5_N |
cd22541 |
N-terminal domain of transcription factor Specificity Protein (SP) 5; Specificity Proteins ... |
977-1108 |
3.88e-03 |
|
N-terminal domain of transcription factor Specificity Protein (SP) 5; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. There are many SPs in vertebrates (9 SPs in humans and mice, 7 SPs in the chicken, and 11 SPs in teleost fish), but arthropods only have 3 SPs. All of them contain clade SP5, which plays a potential role in human cancers and was found in several human tumors including hepatocellular carcinoma, gastric cancer, and colon cancer. Leukemia inhibitor factor/Stat3 and Wnt/beta-catenin signaling pathways converge on SP5 to promote mouse embryonic stem cell self-renewal. SP5 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. This model represents the N-terminal domain of SP5.
Pssm-ID: 412096 [Multi-domain] Cd Length: 143 Bit Score: 39.08 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 977 NMPPSNPYTPIAVASSTVNPAHTYKphggsqiVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSalspsvtpqlPP 1056
Cdd:cd22541 1 MAPHELPLTPPAEPSFHQSLAYSFE-------LSPVKMLPTPAPAPAASAPPHPSPVSSPTQQPQQLP----------PN 63
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 19112374 1057 VSSRLPPVSATRPQIPQPPPVSTALPSSSAVSRPP-IATSAGRSSTAASTSAP 1108
Cdd:cd22541 64 PADDIPWWSIQQSNPAHPPSTSTPLGHPTFAGYQPqIAALLQTKSPAASLSTT 116
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
845-1088 |
4.37e-03 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 41.09 E-value: 4.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 845 PADVHPLPPPSTSTTAgwnDAPMLGQLPMRraAPSMAPVRSPFPGASSAQPAAmsrTSSVSTLPPPPPTASMTASApaia 924
Cdd:PHA03291 167 PAEGTLAAPPLGEGSA---DGSCDPALPLS--APRLGPADVFVPATPRPTPRT---TASPETTPTPSTTTSPPSTT---- 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 925 sppppkvgetyhPPTASGTRVPPVQQPSHPNPYTPvAPQSPVAAASRISSSPNMPPSNPY--TPIAVASSTVNPAHTYKP 1002
Cdd:PHA03291 235 ------------IPAPSTTIAAPQAGTTPEAEGTP-APPTPGGGEAPPANATPAPEASRYelTVTQIIQIAIPASIIACV 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1003 HGGSQIVPPPKQPANRVVPlpptasqRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSatrPQIPQPPPVSTALP 1082
Cdd:PHA03291 302 FLGSCACCLHRRCRRRRRR-------PARIYRPPSPVAPSISAVNEAALARLGDELKRHPPES---PRRSKRRSSQTMVP 371
|
....*.
gi 19112374 1083 SSSAVS 1088
Cdd:PHA03291 372 SLTAIS 377
|
|
| Retinal |
pfam15449 |
Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. ... |
881-1113 |
5.11e-03 |
|
Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. Mutations of the gene encoding this protein have been associated with retinal disorders such as retinitis pigmentosa and late-onset progressive retinal atrophy. The function of this family of proteins is unknown, but it is likely to be important in the development and function of the retina.
Pssm-ID: 464722 [Multi-domain] Cd Length: 1293 Bit Score: 41.30 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 881 APVRSPFPGASSAQPAAMSRTSSVST--LPPPPPTASMTASAPAIASPPPPKVGETyhppTASGTRVPPVQQ-------- 950
Cdd:pfam15449 814 APIFPPLPTAEASKSEDTNCETEEDLehLPPPPLEILMDKSFTSLEPPESSKPAGS----SPEGTPVPGLGEagptrrtw 889
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 951 ---------------PSHPNPyTPVAPQSPVAAASRISSSP-------NMPPSNPYTPIA--VASSTV------------ 994
Cdd:pfam15449 890 aspklrasmspidllPSKSTA-SPTRPRSTGPGSSKSGCNPrklaldlNHPPAASHNPEAegGAQSQAqaeeaaslskqp 968
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 995 -------NPAHT---------------YKPHG-------------GSQIVPPPK----QPANRVVPLPPTASQRASAYEP 1035
Cdd:pfam15449 969 rkaipwhHSSHTsgqsrtsepslarptRGPHSpeaprqsqersppLVRKASPTRahwaPRADKRHPSLPSSHRPAQPSLP 1048
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1036 PTVSVPSPSaLSPSVTPqlPPVSSRL--PPVSATR----PQIPQPPPVSTALPSSSAVSRPPIATSAGRSSTAASTSAPL 1109
Cdd:pfam15449 1049 TVQRSPSPP-LSPRAPS--PPRSPRVlsPPTSKKRtsppPQHKLPSPPPESPPAQHKLSSPPTQRTEASSPSSGPSPSPP 1125
|
....
gi 19112374 1110 TYPA 1113
Cdd:pfam15449 1126 TSPS 1129
|
|
| SOBP |
pfam15279 |
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual ... |
811-1043 |
5.86e-03 |
|
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual disability. It carries a zinc-finger of the zf-C2H2 type at the N-terminus, and a highly characteriztic C-terminal PhPhPhPhPhPh motif. The deduced 873-amino acid protein contains an N-terminal nuclear localization signal (NLS), followed by 2 FCS-type zinc finger motifs, a proline-rich region (PR1), a putative RNA-binding motif region, and a C-terminal NLS embedded in a second proline-rich motif. SOBP is expressed in various human tissues, including developing mouse brain at embryonic day 14. In postnatal and adult mouse brain SOBP is expressed in all neurons, with intense staining in the limbic system. Highest expression is in layer V cortical neurons, hippocampus, pyriform cortex, dorsomedial nucleus of thalamus, amygdala, and hypothalamus. Postnatal expression of SOBP in the limbic system corresponds to a time of active synaptogenesis. the family is also referred to as Jackson circler, JXC1. In seven affected siblings from a consanguineous Israeli Arab family with mental retardation, anterior maxillary protrusion, and strabismus mutations were found in this protein.
Pssm-ID: 464609 [Multi-domain] Cd Length: 325 Bit Score: 40.18 E-value: 5.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 811 PVQPKTSQASSILPTVPRTTSYTSPYATTSShitPADVHPLPPPSTSTTAGwndapmlgQLPMRRAAPSMAPVrSPFPGA 890
Cdd:pfam15279 125 LLAPKPHEPPSLPPPPLPPKKGRRHRPGLHP---PLGRPPGSPPMSMTPRG--------LLGKPQQHPPPSPL-PAFMEP 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 891 SSAQPAAMSRTSSV----STLPPPPPTASMTasapaiasppppkvgetyhPPTASGTRVPPvQQPSHPNPYTPVAPQSPv 966
Cdd:pfam15279 193 SSMPPPFLRPPPSIpqpnSPLSNPMLPGIGP-------------------PPKPPRNLGPP-SNPMHRPPFSPHHPPPP- 251
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 19112374 967 aaASRISSSPNMPPSNPYTPIAVASSTVNPahtykphggsQIVPPPKQPANRVVPLPptasqrASAYEPPTVSVPSP 1043
Cdd:pfam15279 252 --PTPPGPPPGLPPPPPRGFTPPFGPPFPP----------VNMMPNPPEMNFGLPSL------APLVPPVTVLVPYP 310
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
1042-1108 |
6.15e-03 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 40.26 E-value: 6.15e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 19112374 1042 SPSALSPSVTPQLPPVSSRLPPVSATRPqiPQPPPVSTALPSSSaVSRPPIATSAGRSSTAASTSAP 1108
Cdd:TIGR00601 81 TGKVAPPAATPTSAPTPTPSPPASPASG--MSAAPASAVEEKSP-SEESATATAPESPSTSVPSSGS 144
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
995-1112 |
6.20e-03 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 40.23 E-value: 6.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 995 NPAHTYKPHGGSQIVPPPKQPANRV---VPLPP------TASQRASAYEPPTVSVPSPSALSPS---VTPQLPPVSSRLP 1062
Cdd:PHA02682 69 NSACMQRPSGQSPLAPSPACAAPAPacpACAPAapapavTCPAPAPACPPATAPTCPPPAVCPAparPAPACPPSTRQCP 148
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 19112374 1063 PVsatrPQIPQPPPVSTALPSSSAVSRPPIATSAgrSSTAASTSAPLTYP 1112
Cdd:PHA02682 149 PA----PPLPTPKPAPAAKPIFLHNQLPPPDYPA--ASCPTIETAPAASP 192
|
|
| DamX |
COG3266 |
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ... |
936-1104 |
6.92e-03 |
|
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442497 [Multi-domain] Cd Length: 455 Bit Score: 40.60 E-value: 6.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 936 HPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPiAVASSTVNPAHTYKPHGGSQIVPPPKQP 1015
Cdd:COG3266 208 LLLLLASALGEAVAAAAELAALALLAAGAAEVLTARLVLLLLIIGSALKAP-SQASSASAPATTSLGEQQEVSLPPAVAA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1016 AnrvvPLPPTASQRASAyEPPTVSVPSPSALSPsvTPQLPPVSSRLPPVSATRPQIPQPPPV---STALPSSSAVSRPPI 1092
Cdd:COG3266 287 Q----PAAAAAAQPSAV-ALPAAPAAAAAAAAP--AEAAAPQPTAAKPVVTETAAPAAPAPEaaaAAAAPAAPAVAKKLA 359
|
170
....*....|..
gi 19112374 1093 ATSAGRSSTAAS 1104
Cdd:COG3266 360 ADEQWLASQPAS 371
|
|
| PHA03132 |
PHA03132 |
thymidine kinase; Provisional |
1022-1165 |
7.93e-03 |
|
thymidine kinase; Provisional
Pssm-ID: 222997 [Multi-domain] Cd Length: 580 Bit Score: 40.52 E-value: 7.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1022 LPPTASQRASAYE----PPTVSVPSPSALSPSVTPQLPpvssRLPPVSATRPQIPQPPPVSTALPSSSAV-----SRPPI 1092
Cdd:PHA03132 38 TPLGSTSEATSEDdddlYPPRETGSGGGVATSTIYTVP----RPPRGPEQTLDKPDSLPASRELPPGPTPvppggFRGAS 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 19112374 1093 ATSAGRSSTAASTSAPLTYPAgdrSHIPGNLRPIYEMLNAELQRVSQSLPPQMSRVVHDTEKRLNMLFDRLNS 1165
Cdd:PHA03132 114 SPRLGADSTSPRFLYQVNFPV---ILAPIGESNSSSEELSEEEEHSRPPPSESLKVKNGGKVYPKGFSKHKTH 183
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
966-1108 |
8.60e-03 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 40.10 E-value: 8.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 966 VAAASRISSSPNMPPSNPYTPIAVASSTVNPAhtykphggsqivPPPKQPANRVvPLPPTASQRASAYEPPTVSVPSPSA 1045
Cdd:PHA03269 12 IACINLIIANLNTNIPIPELHTSAATQKPDPA------------PAPHQAASRA-PDPAVAPTSAASRKPDLAQAPTPAA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19112374 1046 L-SPSVTPQLPPVSSRLP-PVSAtrPQIPQPPPVSTALPSSSAVSRPPIATSAGrSSTAASTSAP 1108
Cdd:PHA03269 79 SeKFDPAPAPHQAASRAPdPAVA--PQLAAAPKPDAAEAFTSAAQAHEAPADAG-TSAASKKPDP 140
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1023-1116 |
8.60e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 40.18 E-value: 8.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1023 PPTASQRAsayePPTVSVPSPSALSPSV-TPQLPPVSSRLPPVSATR-PQIPQPPPVSTALPSSSAVSR--PPIATSAGR 1098
Cdd:PRK14950 362 PVPAPQPA----KPTAAAPSPVRPTPAPsTRPKAAAAANIPPKEPVReTATPPPVPPRPVAPPVPHTPEsaPKLTRAAIP 437
|
90
....*....|....*...
gi 19112374 1099 SSTAASTSAPLTYPAGDR 1116
Cdd:PRK14950 438 VDEKPKYTPPAPPKEEEK 455
|
|
| MISS |
pfam15822 |
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ... |
877-1108 |
8.75e-03 |
|
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.
Pssm-ID: 318115 [Multi-domain] Cd Length: 238 Bit Score: 39.20 E-value: 8.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 877 APSMAPVRSPF--PGASSAQPAAMSRTSSVSTLPPPPPTASMTASApaiasppppkvgetyhPPTASGTRVPPVQQPSHP 954
Cdd:pfam15822 26 PPQGWPGSNPWnnPSAPPAVPSGLPPSTAPSTVPFGPAPTGMYPSI----------------PLTGPSPGPPAPFPPSGP 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 955 NPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAvasstvnpahtyKPHGGsqivppPKQPAnRVVPLPPTASQRASAYE 1034
Cdd:pfam15822 90 SCPPPGGPYPAPTVPGPGPIGPYPTPNMPFPELP------------RPYGA------PTDPA-AAAPSGPWGSMSSGPWA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1035 P--------PTVSVPSP---SALSPSVTPQ-LPPVSSRLPPVSATRPQIPQPPPV-STALPSSSAVSRPPIATSAGRSST 1101
Cdd:pfam15822 151 PgmggqypaPNMPYPSPgpyPAVPPPQSPGaAPPVPWGTVPPGPWGPPAPYPDPTgSYPMPGLYPTPNNPFQVPSGPSGA 230
|
....*..
gi 19112374 1102 AASTSAP 1108
Cdd:pfam15822 231 PPMPGGP 237
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
934-1117 |
9.74e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 40.23 E-value: 9.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 934 TYHPPTASGT-RVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAhtykPHGGSQIvpPP 1012
Cdd:PRK07994 358 AFHPAAPLPEpEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQL----LAARQQL--QR 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19112374 1013 KQPANRVVPLPPTASQRASayepptvsvPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSssaVSRPPI 1092
Cdd:PRK07994 432 AQGATKAKKSEPAAASRAR---------PVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEP---VATPKA 499
|
170 180
....*....|....*....|....*
gi 19112374 1093 ATSAGRSSTAASTSAPLTYPAGDRS 1117
Cdd:PRK07994 500 LKKALEHEKTPELAAKLAAEAIERD 524
|
|
| |
