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Conserved domains on  [gi|63054773|ref|NP_596135|]
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INCENP-like protein Pic1 [Schizosaccharomyces pombe]

Protein Classification

INCENP ARK-binding domain-containing protein( domain architecture ID 10512226)

inner centromere protein (INCENP) aurora-related kinase (ARK)-binding domain-containing protein, similar to Saccharomyces cerevisiae INCENP-related protein SLI15 that is required for high-fidelity chromosome segregation

CATH:  1.20.5.4970
Gene Ontology:  GO:0032147|GO:0030295
SCOP:  4004344

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
INCENP_ARK-bind pfam03941
Inner centromere protein, ARK binding region; This region of the inner centromere protein has ...
 933-978 1.83e-16

Inner centromere protein, ARK binding region; This region of the inner centromere protein has been found to be necessary and sufficient for binding to aurora-related kinase. This interaction has been implicated in the coordination of chromosome segregation with cell division in yeast.


:

Pssm-ID: 461100 [Multi-domain]  Cd Length: 53  Bit Score: 74.15  E-value: 1.83e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 63054773    933 EGNKKKVNLPSWAESPELREQLKRQQKWDPDKIFGMIKPLQMDEYF 978
Cdd:pfam03941    8 DEDEPRKPVPSWAQSPNLRQALIRQEPIDPDEIFGPIPPLNLEEIF 53
 
Name Accession Description Interval E-value
INCENP_ARK-bind pfam03941
Inner centromere protein, ARK binding region; This region of the inner centromere protein has ...
 933-978 1.83e-16

Inner centromere protein, ARK binding region; This region of the inner centromere protein has been found to be necessary and sufficient for binding to aurora-related kinase. This interaction has been implicated in the coordination of chromosome segregation with cell division in yeast.


Pssm-ID: 461100 [Multi-domain]  Cd Length: 53  Bit Score: 74.15  E-value: 1.83e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 63054773    933 EGNKKKVNLPSWAESPELREQLKRQQKWDPDKIFGMIKPLQMDEYF 978
Cdd:pfam03941    8 DEDEPRKPVPSWAQSPNLRQALIRQEPIDPDEIFGPIPPLNLEEIF 53
 
Name Accession Description Interval E-value
INCENP_ARK-bind pfam03941
Inner centromere protein, ARK binding region; This region of the inner centromere protein has ...
 933-978 1.83e-16

Inner centromere protein, ARK binding region; This region of the inner centromere protein has been found to be necessary and sufficient for binding to aurora-related kinase. This interaction has been implicated in the coordination of chromosome segregation with cell division in yeast.


Pssm-ID: 461100 [Multi-domain]  Cd Length: 53  Bit Score: 74.15  E-value: 1.83e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 63054773    933 EGNKKKVNLPSWAESPELREQLKRQQKWDPDKIFGMIKPLQMDEYF 978
Cdd:pfam03941    8 DEDEPRKPVPSWAQSPNLRQALIRQEPIDPDEIFGPIPPLNLEEIF 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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