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Conserved domains on  [gi|19113444|ref|NP_596652|]
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SWI/SNF complex subunit Snf59 [Schizosaccharomyces pombe]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CRC_subunit pfam08624
Chromatin remodelling complex Rsc7/Swp82 subunit; This family has been identified as a subunit ...
 289-447 3.37e-50

Chromatin remodelling complex Rsc7/Swp82 subunit; This family has been identified as a subunit of chromatin remodelling complexes. Saccharomyces cerevisiae Swiss:P32832 and its paralogue Swiss:P43554 have been identified as subunits of the RSC chromatin remodelling complex, and SWI/SNF chromatin remodelling complex respectively.


:

Pssm-ID: 430112  Cd Length: 134  Bit Score: 168.09  E-value: 3.37e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   289 SDDIAQITSVTPITEKiedkdkyiseVIDTYGKLADGFEYRAKTFCLEGRGKVLYMLGTECSRLLGFKDSYFMFHKTPSL 368
Cdd:pfam08624   1 ENDEYVLPKDDPEGET----------KIDKNGRLLGGREYLFRTFTLPGRGERLYMLSTDLARALGFRDSYLFFRKHPQL 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19113444   369 RKVLTTQSERDQMVEMGLLASNFRFRQLSIVPARQMFLAFGARILMKGTidpeshkalieknisWADDEYYHMDVMANG 447
Cdd:pfam08624  71 YKLIATQEEKDDLIERGLLPSSYRSRQITLVTARSVFREFGARIIVGGK---------------RVIDDYWEQKAREQG 134
PRK08581 super family cl35718
amidase domain-containing protein;
10-229 4.94e-03

amidase domain-containing protein;


The actual alignment was detected with superfamily member PRK08581:

Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 39.39  E-value: 4.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   10 HSDDLNKEESGESNRVNIEEPEHHDNSNKESTnlddlnmlEEPKYHDNSNKESTNLDDlnmlEEPEHHDNSKKESTNLDD 89
Cdd:PRK08581  26 YADDPQKDSTAKTTSHDSKKSNDDETSKDTSS--------KDTDKADNNNTSNQDNND----KKFSTIDSSTSDSNNIID 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   90 S-----------NMLEEPKHHDNSNKEST------NLDDLNMSEEP-----------KHHDSSNKESTNLDNSNMDESEN 141
Cdd:PRK08581  94 FiyknlpqtninQLLTKNKYDDNYSLTTLiqnlfnLNSDISDYEQPrnsekstndsnKNSDSSIKNDTDTQSSKQDKADN 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444  142 QKNFKIEEPKPSGDFRnegpkqcddskiekpelhvNSKIEEPIHRIDSEHnEPEYHTESKNEESEHNTKSIREEPIHHV- 220
Cdd:PRK08581 174 QKAPSSNNTKPSTSNK-------------------QPNSPKPTQPNQSNS-QPASDDTANQKSSSKDNQSMSDSALDSIl 233

                        250
                 ....*....|....
gi 19113444  221 -----DSKNEEPVY 229
Cdd:PRK08581 234 dqyseDAKKTQKDY 247
 
Name Accession Description Interval E-value
CRC_subunit pfam08624
Chromatin remodelling complex Rsc7/Swp82 subunit; This family has been identified as a subunit ...
 289-447 3.37e-50

Chromatin remodelling complex Rsc7/Swp82 subunit; This family has been identified as a subunit of chromatin remodelling complexes. Saccharomyces cerevisiae Swiss:P32832 and its paralogue Swiss:P43554 have been identified as subunits of the RSC chromatin remodelling complex, and SWI/SNF chromatin remodelling complex respectively.


Pssm-ID: 430112  Cd Length: 134  Bit Score: 168.09  E-value: 3.37e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   289 SDDIAQITSVTPITEKiedkdkyiseVIDTYGKLADGFEYRAKTFCLEGRGKVLYMLGTECSRLLGFKDSYFMFHKTPSL 368
Cdd:pfam08624   1 ENDEYVLPKDDPEGET----------KIDKNGRLLGGREYLFRTFTLPGRGERLYMLSTDLARALGFRDSYLFFRKHPQL 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19113444   369 RKVLTTQSERDQMVEMGLLASNFRFRQLSIVPARQMFLAFGARILMKGTidpeshkalieknisWADDEYYHMDVMANG 447
Cdd:pfam08624  71 YKLIATQEEKDDLIERGLLPSSYRSRQITLVTARSVFREFGARIIVGGK---------------RVIDDYWEQKAREQG 134
WH_NTD_SMARCB1_like cd21055
N-terminal winged helix DNA-binding domain found in SMARCB1, PHF10 and similar proteins; The ...
 326-387 1.45e-03

N-terminal winged helix DNA-binding domain found in SMARCB1, PHF10 and similar proteins; The family includes SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) and PHD finger protein 10 (PHF10), both of which have an N-terminal winged helix DNA-binding domain that is structurally related to the SKI/SNO/DAC domain found in a number of metazoan chromatin-associated proteins. SMARCB1, also termed BRG1-associated factor 47 (BAF47), or integrase interactor 1 protein (INI1), or SNF5, or SNF5L1, is a core component of the BAF (hSWI/SNF) complex, an ATP-dependent chromatin-remodeling complex that plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. PHF10, also termed BRG1-associated factor 45a (BAF45a), or XAP135, is involved in transcription activity regulation by chromatin remodeling. It is a component of the neural progenitors-specific chromatin remodeling complex (npBAF complex) and plays a role in the proliferation of neural progenitors.


Pssm-ID: 411034  Cd Length: 80  Bit Score: 37.49  E-value: 1.45e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19113444 326 FEYRaktfcLEGRGKVLYMLGTECSRLLGFKDSyfMFHKTPSLRKVLTTQSERDQMVEMGLL 387
Cdd:cd21055   3 FEYQ-----WPPKSGEYYMLQSQVGEYLGVRGS--LYRKYPDLWRRQATAEERKYLKELGLV 57
PRK08581 PRK08581
amidase domain-containing protein;
10-229 4.94e-03

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 39.39  E-value: 4.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   10 HSDDLNKEESGESNRVNIEEPEHHDNSNKESTnlddlnmlEEPKYHDNSNKESTNLDDlnmlEEPEHHDNSKKESTNLDD 89
Cdd:PRK08581  26 YADDPQKDSTAKTTSHDSKKSNDDETSKDTSS--------KDTDKADNNNTSNQDNND----KKFSTIDSSTSDSNNIID 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   90 S-----------NMLEEPKHHDNSNKEST------NLDDLNMSEEP-----------KHHDSSNKESTNLDNSNMDESEN 141
Cdd:PRK08581  94 FiyknlpqtninQLLTKNKYDDNYSLTTLiqnlfnLNSDISDYEQPrnsekstndsnKNSDSSIKNDTDTQSSKQDKADN 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444  142 QKNFKIEEPKPSGDFRnegpkqcddskiekpelhvNSKIEEPIHRIDSEHnEPEYHTESKNEESEHNTKSIREEPIHHV- 220
Cdd:PRK08581 174 QKAPSSNNTKPSTSNK-------------------QPNSPKPTQPNQSNS-QPASDDTANQKSSSKDNQSMSDSALDSIl 233

                        250
                 ....*....|....
gi 19113444  221 -----DSKNEEPVY 229
Cdd:PRK08581 234 dqyseDAKKTQKDY 247
 
Name Accession Description Interval E-value
CRC_subunit pfam08624
Chromatin remodelling complex Rsc7/Swp82 subunit; This family has been identified as a subunit ...
 289-447 3.37e-50

Chromatin remodelling complex Rsc7/Swp82 subunit; This family has been identified as a subunit of chromatin remodelling complexes. Saccharomyces cerevisiae Swiss:P32832 and its paralogue Swiss:P43554 have been identified as subunits of the RSC chromatin remodelling complex, and SWI/SNF chromatin remodelling complex respectively.


Pssm-ID: 430112  Cd Length: 134  Bit Score: 168.09  E-value: 3.37e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   289 SDDIAQITSVTPITEKiedkdkyiseVIDTYGKLADGFEYRAKTFCLEGRGKVLYMLGTECSRLLGFKDSYFMFHKTPSL 368
Cdd:pfam08624   1 ENDEYVLPKDDPEGET----------KIDKNGRLLGGREYLFRTFTLPGRGERLYMLSTDLARALGFRDSYLFFRKHPQL 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19113444   369 RKVLTTQSERDQMVEMGLLASNFRFRQLSIVPARQMFLAFGARILMKGTidpeshkalieknisWADDEYYHMDVMANG 447
Cdd:pfam08624  71 YKLIATQEEKDDLIERGLLPSSYRSRQITLVTARSVFREFGARIIVGGK---------------RVIDDYWEQKAREQG 134
WH_NTD_SMARCB1_like cd21055
N-terminal winged helix DNA-binding domain found in SMARCB1, PHF10 and similar proteins; The ...
 326-387 1.45e-03

N-terminal winged helix DNA-binding domain found in SMARCB1, PHF10 and similar proteins; The family includes SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) and PHD finger protein 10 (PHF10), both of which have an N-terminal winged helix DNA-binding domain that is structurally related to the SKI/SNO/DAC domain found in a number of metazoan chromatin-associated proteins. SMARCB1, also termed BRG1-associated factor 47 (BAF47), or integrase interactor 1 protein (INI1), or SNF5, or SNF5L1, is a core component of the BAF (hSWI/SNF) complex, an ATP-dependent chromatin-remodeling complex that plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. PHF10, also termed BRG1-associated factor 45a (BAF45a), or XAP135, is involved in transcription activity regulation by chromatin remodeling. It is a component of the neural progenitors-specific chromatin remodeling complex (npBAF complex) and plays a role in the proliferation of neural progenitors.


Pssm-ID: 411034  Cd Length: 80  Bit Score: 37.49  E-value: 1.45e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19113444 326 FEYRaktfcLEGRGKVLYMLGTECSRLLGFKDSyfMFHKTPSLRKVLTTQSERDQMVEMGLL 387
Cdd:cd21055   3 FEYQ-----WPPKSGEYYMLQSQVGEYLGVRGS--LYRKYPDLWRRQATAEERKYLKELGLV 57
WH_NTD_SMARCB1 cd21086
N-terminal winged helix DNA-binding domain found in SWI/SNF-related matrix-associated ...
 331-390 1.59e-03

N-terminal winged helix DNA-binding domain found in SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) and similar proteins; SMARCB1, also termed BRG1-associated factor 47 (BAF47), or integrase interactor 1 protein (INI1), or SNF5, or SNF5L1, is a core component of the BAF (hSWI/SNF) complex, an ATP-dependent chromatin-remodeling complex that plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The model corresponds to the N-terminal winged helix DNA binding domain of SMARCB1, which is structurally related to the SKI/SNO/DAC domain that is found in a number of metazoan chromatin-associated proteins.


Pssm-ID: 411036  Cd Length: 88  Bit Score: 37.60  E-value: 1.59e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19113444 331 KTFCLEGRGkVLYMLGTECSRLLG-FKDSyfMFHKTPSLRKVLTTQSERDQMVEMGL----LASN 390
Cdd:cd21086   7 RSFQLEEDG-ERYMIGSEVGNYLRlFRGS--LYKKYPGLWRRQATSEERKKLVELGLsqhsLATN 68
PRK08581 PRK08581
amidase domain-containing protein;
10-229 4.94e-03

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 39.39  E-value: 4.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   10 HSDDLNKEESGESNRVNIEEPEHHDNSNKESTnlddlnmlEEPKYHDNSNKESTNLDDlnmlEEPEHHDNSKKESTNLDD 89
Cdd:PRK08581  26 YADDPQKDSTAKTTSHDSKKSNDDETSKDTSS--------KDTDKADNNNTSNQDNND----KKFSTIDSSTSDSNNIID 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444   90 S-----------NMLEEPKHHDNSNKEST------NLDDLNMSEEP-----------KHHDSSNKESTNLDNSNMDESEN 141
Cdd:PRK08581  94 FiyknlpqtninQLLTKNKYDDNYSLTTLiqnlfnLNSDISDYEQPrnsekstndsnKNSDSSIKNDTDTQSSKQDKADN 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113444  142 QKNFKIEEPKPSGDFRnegpkqcddskiekpelhvNSKIEEPIHRIDSEHnEPEYHTESKNEESEHNTKSIREEPIHHV- 220
Cdd:PRK08581 174 QKAPSSNNTKPSTSNK-------------------QPNSPKPTQPNQSNS-QPASDDTANQKSSSKDNQSMSDSALDSIl 233

                        250
                 ....*....|....
gi 19113444  221 -----DSKNEEPVY 229
Cdd:PRK08581 234 dqyseDAKKTQKDY 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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