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Conserved domains on  [gi|19113505|ref|NP_596713|]
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U3 snoRNP protein Utp20 [Schizosaccharomyces pombe]

Protein Classification

UTP20 family protein( domain architecture ID 10540292)

UTP20 (U three protein 20) family protein similar to Saccharomyces cerevisiae U3 small nucleolar RNA-associated protein 20, also called UTP20, that is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
DRIM pfam07539
Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In ...
 815-1417 2.23e-178

Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In Metastasis), which is differentially expressed in metastatic and non-metastatic human breast carcinoma cells. It is believed to be involved in processing of non-coding RNA.


:

Pssm-ID: 462198  Cd Length: 609  Bit Score: 560.66  E-value: 2.23e-178
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    815 WARPDVYLLLGLYSKFTGIKEFVNRDARKEFFLWALTINDPKVQKLVLDIILLYSEEAITTYEENLRNLLDDKKCRDELI 894
Cdd:pfam07539    1 WSRKDLKALLKLFAKFKNPKALYKSDELYEALLDLLSNGDAEVQKLALDCLLTWKDPAVVPYKENLKNLLDDTRFRDELT 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    895 TFLFVDyADSKIQDIHRPLLMPVVISILYGKMVSK---GYGGQKNQAARRSTILSALGNMQVEDLQILVDIMLRPYNGLE 971
Cdd:pfam07539   81 VFLQSD-EDSVIEPEHRPELMPVLLRILYGRMISKkgsRSSGKAGQQARRKAVLRFLAGLSEEELGLFLDLALGPLKYVS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    972 VKLNANNNLE-IDTGNIPSLTLRRQIGFLTMTEELLLQISSKLSSVAPKILNAVLYNLVVSDDQISSQ---EAFENFEVK 1047
Cdd:pfam07539  160 VVDESVEFFEnGDELLSEVLPLRRQLGFLNLLEDVLKVLGSKLAPYLPKLLNPLLYCLVAAQRRLDQEdeeEEEEGILLK 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1048 MAYTVRQLSLKVFLLFLKSCSDVDFKPYNVFIYTAFVVPRLDRFADENTQSVSNLMKIFRCWFENEAYLDSVLEFSSHIL 1127
Cdd:pfam07539  240 LLRNIRQLGLKCLVDLFQNFGDFDWTPYIDAIFEEVISPRLEKLAVENLQSPSALLKLFHTWSKNPRYAPFLVKYDSAVL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1128 TALLNTASHTAVKLPVLLYILDTLNLVITHLQSEESESQLREKILANLVMPNITLIFASLSNILKNpQFCNNNRVMDGSV 1207
Cdd:pfam07539  320 PAVIELLSNPKAKPSVVLFVLDIVENLLTLADEEDEEEEDSEDIGSELLLPHVSSLLQHLPALLER-SKTPSKELLSREL 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1208 QALSAVSEYMSLDIDSSPLLNLLVSFLRKPNRLVPSNVKSNILVLLCKLLPTNTKwLHASISQTNDFDTIMHLYTSMVDI 1287
Cdd:pfam07539  399 SILSRLAPYVTDSEQASSLLDLLLPLLRKPSRRVSPKTKVDLLKILSNLLPLYDC-SWDDILPEKLYKTLSSLFSTFKDR 477

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1288 KARQHLNDLLKIYSTIDDNLIFSSVFVEEINSISKKRLDEPDFERRLSAFTSFNEKHFSLISDLAWLPVLYNFFFYVQDA 1367
Cdd:pfam07539  478 ESREALCKVFKALAKKDPELEEVADLVADLNAYSTRRLDEPDFDRRLSAFKKINEELYKSLTARQWLPLLYNCLFFIRDE 557

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 19113505   1368 EELAIRASASLGIKRFIESITMNDASNQFKI--DVFVKFIFPFIKNQMKNKN 1417
Cdd:pfam07539  558 EELAIRSNASHCLKRFIDAAASKSSEEEKEEfeDLLKDVLLPALRRGLRSKS 609
DUF6700 pfam20416
Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which ...
 1622-1839 8.24e-84

Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which associated with the U3 snRNA.


:

Pssm-ID: 466565  Cd Length: 221  Bit Score: 274.41  E-value: 8.24e-84
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1622 DESTVTLRVAIALSIVQLVALLPEEEIVLRLTPVLIDTCHILRSRSLESRDATRKALAAISKFLGPKYFSFIISQLQTSL 1701
Cdd:pfam20416    4 EEDEDVLRVPVALAIVKLLQLLPEKSLEVNLPGLLLKLCQFLRSRSQEVRDLARETLVKILETLGPKYLPFILKELKSAL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1702 KRGYQLHVLGYTVHYLLLAIEDVYPYGSIDYCMDSLAQIFVDEIFGEVGVEKDSEDYKSNVKEIKGNKSYDSYEIVARIS 1781
Cdd:pfam20416   84 TRGYQLHVLSYTVHSLLVALEPTLEPGDLDSCLEDILDIIMDDIFGEVAEEKEVEEITSKMKEAKSSKSYDTFEILAQFI 163

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 19113505   1782 SFDSLSTLLRPVKNVLFETNVPKSLRKVDELCRRLSLGIVANKQSASQSSLIFCYNVY 1839
Cdd:pfam20416  164 SFNALHDLLLPLKEILHETESAKTLRKVEELLRRIALGLSANPSLSSEDLLIFCYGLI 221
 
Name Accession Description Interval E-value
DRIM pfam07539
Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In ...
 815-1417 2.23e-178

Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In Metastasis), which is differentially expressed in metastatic and non-metastatic human breast carcinoma cells. It is believed to be involved in processing of non-coding RNA.


Pssm-ID: 462198  Cd Length: 609  Bit Score: 560.66  E-value: 2.23e-178
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    815 WARPDVYLLLGLYSKFTGIKEFVNRDARKEFFLWALTINDPKVQKLVLDIILLYSEEAITTYEENLRNLLDDKKCRDELI 894
Cdd:pfam07539    1 WSRKDLKALLKLFAKFKNPKALYKSDELYEALLDLLSNGDAEVQKLALDCLLTWKDPAVVPYKENLKNLLDDTRFRDELT 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    895 TFLFVDyADSKIQDIHRPLLMPVVISILYGKMVSK---GYGGQKNQAARRSTILSALGNMQVEDLQILVDIMLRPYNGLE 971
Cdd:pfam07539   81 VFLQSD-EDSVIEPEHRPELMPVLLRILYGRMISKkgsRSSGKAGQQARRKAVLRFLAGLSEEELGLFLDLALGPLKYVS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    972 VKLNANNNLE-IDTGNIPSLTLRRQIGFLTMTEELLLQISSKLSSVAPKILNAVLYNLVVSDDQISSQ---EAFENFEVK 1047
Cdd:pfam07539  160 VVDESVEFFEnGDELLSEVLPLRRQLGFLNLLEDVLKVLGSKLAPYLPKLLNPLLYCLVAAQRRLDQEdeeEEEEGILLK 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1048 MAYTVRQLSLKVFLLFLKSCSDVDFKPYNVFIYTAFVVPRLDRFADENTQSVSNLMKIFRCWFENEAYLDSVLEFSSHIL 1127
Cdd:pfam07539  240 LLRNIRQLGLKCLVDLFQNFGDFDWTPYIDAIFEEVISPRLEKLAVENLQSPSALLKLFHTWSKNPRYAPFLVKYDSAVL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1128 TALLNTASHTAVKLPVLLYILDTLNLVITHLQSEESESQLREKILANLVMPNITLIFASLSNILKNpQFCNNNRVMDGSV 1207
Cdd:pfam07539  320 PAVIELLSNPKAKPSVVLFVLDIVENLLTLADEEDEEEEDSEDIGSELLLPHVSSLLQHLPALLER-SKTPSKELLSREL 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1208 QALSAVSEYMSLDIDSSPLLNLLVSFLRKPNRLVPSNVKSNILVLLCKLLPTNTKwLHASISQTNDFDTIMHLYTSMVDI 1287
Cdd:pfam07539  399 SILSRLAPYVTDSEQASSLLDLLLPLLRKPSRRVSPKTKVDLLKILSNLLPLYDC-SWDDILPEKLYKTLSSLFSTFKDR 477

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1288 KARQHLNDLLKIYSTIDDNLIFSSVFVEEINSISKKRLDEPDFERRLSAFTSFNEKHFSLISDLAWLPVLYNFFFYVQDA 1367
Cdd:pfam07539  478 ESREALCKVFKALAKKDPELEEVADLVADLNAYSTRRLDEPDFDRRLSAFKKINEELYKSLTARQWLPLLYNCLFFIRDE 557

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 19113505   1368 EELAIRASASLGIKRFIESITMNDASNQFKI--DVFVKFIFPFIKNQMKNKN 1417
Cdd:pfam07539  558 EELAIRSNASHCLKRFIDAAASKSSEEEKEEfeDLLKDVLLPALRRGLRSKS 609
DUF6700 pfam20416
Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which ...
 1622-1839 8.24e-84

Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which associated with the U3 snRNA.


Pssm-ID: 466565  Cd Length: 221  Bit Score: 274.41  E-value: 8.24e-84
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1622 DESTVTLRVAIALSIVQLVALLPEEEIVLRLTPVLIDTCHILRSRSLESRDATRKALAAISKFLGPKYFSFIISQLQTSL 1701
Cdd:pfam20416    4 EEDEDVLRVPVALAIVKLLQLLPEKSLEVNLPGLLLKLCQFLRSRSQEVRDLARETLVKILETLGPKYLPFILKELKSAL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1702 KRGYQLHVLGYTVHYLLLAIEDVYPYGSIDYCMDSLAQIFVDEIFGEVGVEKDSEDYKSNVKEIKGNKSYDSYEIVARIS 1781
Cdd:pfam20416   84 TRGYQLHVLSYTVHSLLVALEPTLEPGDLDSCLEDILDIIMDDIFGEVAEEKEVEEITSKMKEAKSSKSYDTFEILAQFI 163

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 19113505   1782 SFDSLSTLLRPVKNVLFETNVPKSLRKVDELCRRLSLGIVANKQSASQSSLIFCYNVY 1839
Cdd:pfam20416  164 SFNALHDLLLPLKEILHETESAKTLRKVEELLRRIALGLSANPSLSSEDLLIFCYGLI 221
 
Name Accession Description Interval E-value
DRIM pfam07539
Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In ...
 815-1417 2.23e-178

Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In Metastasis), which is differentially expressed in metastatic and non-metastatic human breast carcinoma cells. It is believed to be involved in processing of non-coding RNA.


Pssm-ID: 462198  Cd Length: 609  Bit Score: 560.66  E-value: 2.23e-178
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    815 WARPDVYLLLGLYSKFTGIKEFVNRDARKEFFLWALTINDPKVQKLVLDIILLYSEEAITTYEENLRNLLDDKKCRDELI 894
Cdd:pfam07539    1 WSRKDLKALLKLFAKFKNPKALYKSDELYEALLDLLSNGDAEVQKLALDCLLTWKDPAVVPYKENLKNLLDDTRFRDELT 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    895 TFLFVDyADSKIQDIHRPLLMPVVISILYGKMVSK---GYGGQKNQAARRSTILSALGNMQVEDLQILVDIMLRPYNGLE 971
Cdd:pfam07539   81 VFLQSD-EDSVIEPEHRPELMPVLLRILYGRMISKkgsRSSGKAGQQARRKAVLRFLAGLSEEELGLFLDLALGPLKYVS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505    972 VKLNANNNLE-IDTGNIPSLTLRRQIGFLTMTEELLLQISSKLSSVAPKILNAVLYNLVVSDDQISSQ---EAFENFEVK 1047
Cdd:pfam07539  160 VVDESVEFFEnGDELLSEVLPLRRQLGFLNLLEDVLKVLGSKLAPYLPKLLNPLLYCLVAAQRRLDQEdeeEEEEGILLK 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1048 MAYTVRQLSLKVFLLFLKSCSDVDFKPYNVFIYTAFVVPRLDRFADENTQSVSNLMKIFRCWFENEAYLDSVLEFSSHIL 1127
Cdd:pfam07539  240 LLRNIRQLGLKCLVDLFQNFGDFDWTPYIDAIFEEVISPRLEKLAVENLQSPSALLKLFHTWSKNPRYAPFLVKYDSAVL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1128 TALLNTASHTAVKLPVLLYILDTLNLVITHLQSEESESQLREKILANLVMPNITLIFASLSNILKNpQFCNNNRVMDGSV 1207
Cdd:pfam07539  320 PAVIELLSNPKAKPSVVLFVLDIVENLLTLADEEDEEEEDSEDIGSELLLPHVSSLLQHLPALLER-SKTPSKELLSREL 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1208 QALSAVSEYMSLDIDSSPLLNLLVSFLRKPNRLVPSNVKSNILVLLCKLLPTNTKwLHASISQTNDFDTIMHLYTSMVDI 1287
Cdd:pfam07539  399 SILSRLAPYVTDSEQASSLLDLLLPLLRKPSRRVSPKTKVDLLKILSNLLPLYDC-SWDDILPEKLYKTLSSLFSTFKDR 477

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1288 KARQHLNDLLKIYSTIDDNLIFSSVFVEEINSISKKRLDEPDFERRLSAFTSFNEKHFSLISDLAWLPVLYNFFFYVQDA 1367
Cdd:pfam07539  478 ESREALCKVFKALAKKDPELEEVADLVADLNAYSTRRLDEPDFDRRLSAFKKINEELYKSLTARQWLPLLYNCLFFIRDE 557

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 19113505   1368 EELAIRASASLGIKRFIESITMNDASNQFKI--DVFVKFIFPFIKNQMKNKN 1417
Cdd:pfam07539  558 EELAIRSNASHCLKRFIDAAASKSSEEEKEEfeDLLKDVLLPALRRGLRSKS 609
DUF6700 pfam20416
Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which ...
 1622-1839 8.24e-84

Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which associated with the U3 snRNA.


Pssm-ID: 466565  Cd Length: 221  Bit Score: 274.41  E-value: 8.24e-84
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1622 DESTVTLRVAIALSIVQLVALLPEEEIVLRLTPVLIDTCHILRSRSLESRDATRKALAAISKFLGPKYFSFIISQLQTSL 1701
Cdd:pfam20416    4 EEDEDVLRVPVALAIVKLLQLLPEKSLEVNLPGLLLKLCQFLRSRSQEVRDLARETLVKILETLGPKYLPFILKELKSAL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19113505   1702 KRGYQLHVLGYTVHYLLLAIEDVYPYGSIDYCMDSLAQIFVDEIFGEVGVEKDSEDYKSNVKEIKGNKSYDSYEIVARIS 1781
Cdd:pfam20416   84 TRGYQLHVLSYTVHSLLVALEPTLEPGDLDSCLEDILDIIMDDIFGEVAEEKEVEEITSKMKEAKSSKSYDTFEILAQFI 163

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 19113505   1782 SFDSLSTLLRPVKNVLFETNVPKSLRKVDELCRRLSLGIVANKQSASQSSLIFCYNVY 1839
Cdd:pfam20416  164 SFNALHDLLLPLKEILHETESAKTLRKVEELLRRIALGLSANPSLSSEDLLIFCYGLI 221
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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