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solute carrier family 12 member 6 isoform a [Homo sapiens]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
109-1150
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1357.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 109 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKTPQM G T 187
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 188 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 267
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 268 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIFHSD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 347
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLLREN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 348 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhidvcsktkeinnmtvpsklwgffcnssqffnatcdey F VH N 427
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 428 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgslnheyvlvditts F TL L V GIFFPSVTGI M AG S N R SG 507
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 508 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 566
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 567 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 645
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 646 L S M FFL MC Y LFV N LA C ALQT LLR T P N WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 725
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 726 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 805
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 806 EA L AAE QT I KHLM E AE KVK G F CQL VVA AK LREG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 885
Cdd:TIGR00930 621 EA Q AAE AK I QTWL E KN KVK A F YAV VVA DD LREG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 886 AHLA LL V AK N ISFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 927
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 928 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 1007
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 1008 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkaksmegf QD L lnmrpd QSNVR RMHTA 1087
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 110224449 1088 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1150
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
109-1150
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1357.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 109 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKTPQM G T 187
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 188 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 267
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 268 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIFHSD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 347
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLLREN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 348 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhidvcsktkeinnmtvpsklwgffcnssqffnatcdey F VH N 427
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 428 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgslnheyvlvditts F TL L V GIFFPSVTGI M AG S N R SG 507
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 508 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 566
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 567 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 645
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 646 L S M FFL MC Y LFV N LA C ALQT LLR T P N WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 725
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 726 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 805
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 806 EA L AAE QT I KHLM E AE KVK G F CQL VVA AK LREG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 885
Cdd:TIGR00930 621 EA Q AAE AK I QTWL E KN KVK A F YAV VVA DD LREG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 886 AHLA LL V AK N ISFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 927
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 928 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 1007
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 1008 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkaksmegf QD L lnmrpd QSNVR RMHTA 1087
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 110224449 1088 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1150
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
190-760
7.98e-49
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 180.98
E-value: 7.98e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 190 G V YLPC L QNIF G VI LF LRLTW V V G T AG VLQ A FAIV LI CCCCTM L TAI S MSA I A TNG V V p A GG S Y FMI SR A LGP EF G G A V G 269
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGS V L G Q AG PAG A LLGY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 270 L -- CFYLG T TF A AA myi L G A IE I FLVYIVPRAA I fhsddalkesaaml NNMR V Y G TA FLVL MVLVVFI GV RYVNKFASL F 347
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS I LIQFWELVPD I -------------- PYLW V W G AV FLVL LTIINLV GV KWYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 348 LACV I VS I LAIYAGA I -- K S SFA P PHFPV cmlgnrtlssrhidvcsktkeinnmtvpsklwgffcnssqffnatcd EYFV 425
Cdd:pfam00324 143 ALIK I IA I IGFIIVG I il L S GGN P NDGAI ----------------------------------------------- FRYL 175
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 426 HN N VTSIQGI PG LAS G I I tenlwsnylpkgeiiekpsakssdvlgslnhe Y V L V dittsftllvg I F F PSV TGI MAGSNR 505
Cdd:pfam00324 176 GD N GGKNNFP PG FGK G F I -------------------------------- S V F V ----------- I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 506 S G DL K DAQ KSIP IGTILA I LTTSFV Y LSNVVLF G ACIEG -- VV L RDKFGD A VKGNLVVGTLSWP S -- PWV I VIGSFFSTC 581
Cdd:pfam00324 213 A G EV K NPE KSIP KAILQV I WRITIF Y ILSLLAI G LLVPW nd PG L LNDSAS A ASPFVIFFKFLGI S gl APL I NAVILTAAL 292
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 582 G A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHSKAN G E P TW A L L LTAA I AE L GI L I ASL dl VAP I LSM F F L MCYLFVN L AC 661
Cdd:pfam00324 293 S A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L ASL -- NPA I VFN F L L AISGLSG L IV 368
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 662 ALQTL L RTPNW R PR F R Y YHWALSFMGMSIC L ALMFISSWYY AI VAMV I AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAARFA 741
Cdd:pfam00324 369 WGLIS L SHLRF R KA F K Y QGRSIDELPFKAP L GPLGVILGLA AI IIIL I IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVLLF 448
570
....*....|....*....
gi 110224449 742 L LR L EEGPP H T KNW R PQLL 760
Cdd:pfam00324 449 L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
198-720
1.36e-35
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 141.19
E-value: 1.36e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 198 N I F G VIL F LRLTWVV G T AG -- VLQ A FA I VLICC cct M L T A I S MSAI A TN gv V P - AGG S Y FMIS RALGP EF G GAV G LCFY L 274
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG pa AIL A WL I AGLLA --- L L V A L S YAEL A SA -- F P r AGG A Y TYAR RALGP LL G FLA G WALL L 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 275 GTTF A A A MYILGAIE i F L VYIV P RAAIF hsddalkesaamlnnmr VYGTAFLV L MV L VVFI GV RYVN K FASLFLACVIVS 354
Cdd:COG0531 100 SYVL A V A AVAVAFGG - Y L SSLF P AGGSV ----------------- LIALVLIL L LT L LNLR GV KESA K VNNILTVLKLLV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 355 I L AIYAGAI k SS F A P PH F pvcmlgnrtlssrhidvcsktkeinnmtvpsklwgffcns SQ F FN A T cdeyfvhnnvtsi Q G 434
Cdd:COG0531 162 L L LFIVVGL - FA F D P AN F ---------------------------------------- TP F LP A G ------------- G G 187
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 435 IP G LASGI itenlwsnylpkgeiiekpsakssdvlgslnheyvlvdittsftllv GIF F PSV TG IM A GS N RSGDL K DAQK 514
Cdd:COG0531 188 LS G VLAAL ----------------------------------------------- ALA F FAF TG FE A IA N LAEEA K NPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 515 S IP IGT IL AI L TTSFV Y lsnv V L FGACIE GVV LR D KFGDAVKGNLVVGTLSWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 592
Cdd:COG0531 221 N IP RAI IL SL L IVGVL Y ---- I L VSLALT GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 593 RLL Q A I A K D NII P fl R VF GH - SKAN G E P TW A L LLT AA IA E L GI L I -- AS LDLV A PIL S MFF L MC YL F V N LA c ALQTLL R T 669
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA - VIVLRR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 110224449 670 P NWRPR FR YYHWALSFM G MSI CL A L MFIS --- SWYYAI V AMV I AGMI Y KYIEYQ 720
Cdd:COG0531 374 P DLPRP FR VPLPLIPIL G ILL CL F L LYLL gpg ALLIGL V LLA I GLLL Y LLYRRR 427
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
109-1150
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1357.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 109 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKTPQM G T 187
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 188 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 267
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 268 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIFHSD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 347
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLLREN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 348 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhidvcsktkeinnmtvpsklwgffcnssqffnatcdey F VH N 427
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 428 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgslnheyvlvditts F TL L V GIFFPSVTGI M AG S N R SG 507
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 508 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 566
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 567 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 645
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 646 L S M FFL MC Y LFV N LA C ALQT LLR T P N WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 725
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 726 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 805
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 806 EA L AAE QT I KHLM E AE KVK G F CQL VVA AK LREG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 885
Cdd:TIGR00930 621 EA Q AAE AK I QTWL E KN KVK A F YAV VVA DD LREG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 886 AHLA LL V AK N ISFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 927
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 928 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 1007
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 1008 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkaksmegf QD L lnmrpd QSNVR RMHTA 1087
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 110224449 1088 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1150
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
190-760
7.98e-49
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 180.98
E-value: 7.98e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 190 G V YLPC L QNIF G VI LF LRLTW V V G T AG VLQ A FAIV LI CCCCTM L TAI S MSA I A TNG V V p A GG S Y FMI SR A LGP EF G G A V G 269
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGS V L G Q AG PAG A LLGY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 270 L -- CFYLG T TF A AA myi L G A IE I FLVYIVPRAA I fhsddalkesaaml NNMR V Y G TA FLVL MVLVVFI GV RYVNKFASL F 347
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS I LIQFWELVPD I -------------- PYLW V W G AV FLVL LTIINLV GV KWYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 348 LACV I VS I LAIYAGA I -- K S SFA P PHFPV cmlgnrtlssrhidvcsktkeinnmtvpsklwgffcnssqffnatcd EYFV 425
Cdd:pfam00324 143 ALIK I IA I IGFIIVG I il L S GGN P NDGAI ----------------------------------------------- FRYL 175
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 426 HN N VTSIQGI PG LAS G I I tenlwsnylpkgeiiekpsakssdvlgslnhe Y V L V dittsftllvg I F F PSV TGI MAGSNR 505
Cdd:pfam00324 176 GD N GGKNNFP PG FGK G F I -------------------------------- S V F V ----------- I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 506 S G DL K DAQ KSIP IGTILA I LTTSFV Y LSNVVLF G ACIEG -- VV L RDKFGD A VKGNLVVGTLSWP S -- PWV I VIGSFFSTC 581
Cdd:pfam00324 213 A G EV K NPE KSIP KAILQV I WRITIF Y ILSLLAI G LLVPW nd PG L LNDSAS A ASPFVIFFKFLGI S gl APL I NAVILTAAL 292
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 582 G A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHSKAN G E P TW A L L LTAA I AE L GI L I ASL dl VAP I LSM F F L MCYLFVN L AC 661
Cdd:pfam00324 293 S A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L ASL -- NPA I VFN F L L AISGLSG L IV 368
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 662 ALQTL L RTPNW R PR F R Y YHWALSFMGMSIC L ALMFISSWYY AI VAMV I AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAARFA 741
Cdd:pfam00324 369 WGLIS L SHLRF R KA F K Y QGRSIDELPFKAP L GPLGVILGLA AI IIIL I IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVLLF 448
570
....*....|....*....
gi 110224449 742 L LR L EEGPP H T KNW R PQLL 760
Cdd:pfam00324 449 L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
198-720
1.36e-35
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 141.19
E-value: 1.36e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 198 N I F G VIL F LRLTWVV G T AG -- VLQ A FA I VLICC cct M L T A I S MSAI A TN gv V P - AGG S Y FMIS RALGP EF G GAV G LCFY L 274
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG pa AIL A WL I AGLLA --- L L V A L S YAEL A SA -- F P r AGG A Y TYAR RALGP LL G FLA G WALL L 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 275 GTTF A A A MYILGAIE i F L VYIV P RAAIF hsddalkesaamlnnmr VYGTAFLV L MV L VVFI GV RYVN K FASLFLACVIVS 354
Cdd:COG0531 100 SYVL A V A AVAVAFGG - Y L SSLF P AGGSV ----------------- LIALVLIL L LT L LNLR GV KESA K VNNILTVLKLLV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 355 I L AIYAGAI k SS F A P PH F pvcmlgnrtlssrhidvcsktkeinnmtvpsklwgffcns SQ F FN A T cdeyfvhnnvtsi Q G 434
Cdd:COG0531 162 L L LFIVVGL - FA F D P AN F ---------------------------------------- TP F LP A G ------------- G G 187
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 435 IP G LASGI itenlwsnylpkgeiiekpsakssdvlgslnheyvlvdittsftllv GIF F PSV TG IM A GS N RSGDL K DAQK 514
Cdd:COG0531 188 LS G VLAAL ----------------------------------------------- ALA F FAF TG FE A IA N LAEEA K NPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 515 S IP IGT IL AI L TTSFV Y lsnv V L FGACIE GVV LR D KFGDAVKGNLVVGTLSWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 592
Cdd:COG0531 221 N IP RAI IL SL L IVGVL Y ---- I L VSLALT GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 593 RLL Q A I A K D NII P fl R VF GH - SKAN G E P TW A L LLT AA IA E L GI L I -- AS LDLV A PIL S MFF L MC YL F V N LA c ALQTLL R T 669
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA - VIVLRR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 110224449 670 P NWRPR FR YYHWALSFM G MSI CL A L MFIS --- SWYYAI V AMV I AGMI Y KYIEYQ 720
Cdd:COG0531 374 P DLPRP FR VPLPLIPIL G ILL CL F L LYLL gpg ALLIGL V LLA I GLLL Y LLYRRR 427
SLC12
pfam03522 Solute carrier family 12;
774-1150
5.28e-31
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 126.96
E-value: 5.28e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 774 P R L LT FA SQLKAGKG L T I V G S V IV G NFLENYGEA L AAE qt IKHLMEAE K V K G F CQ LV VAAK LREG ISH L I Q SC GLG GM K H 853
Cdd:pfam03522 2 P A L VD FA HLITKNVS L M I C G H V VK G RLSQKLRSE L QKK -- AYRWLRKR K I K A F YA LV DGDN LREG AQA L L Q AS GLG KL K P 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 854 N TVV MG WPNG WR QSE ------------ DA --------------------------------------------------- 870
Cdd:pfam03522 80 N ILL MG YKSD WR TCD keeleeyfnvih DA fdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 871 -- RAWKTFIGTVRVTTAAH L ALLV ------------------- AKN I SFFPSNV E -------- QF ---- SE G N IDVWW IV 917
Cdd:pfam03522 160 ns KQDDDKSKLSKKDSNLS L SPDK stknpsgkdssksdklkkk SPS I ILRTASN E keilnnit QF qkkq KK G T IDVWW LY 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 918 H DGG MLM LLP FL L KQHKV W RK C SI R I F TVAQLE D NSIQMKKDL A TF L YHL RI E - AEVE V V emhd S DI SAYTYER T LMMEQ 996
Cdd:pfam03522 240 D DGG LTL LLP YI L STRSK W SD C KL R V F ALGNRK D ELEEEQRNM A SL L SKF RI D y SDLT V I ---- P DI TKKPKKE T KKFFD 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 997 rs QMLRHM RL SKTERDR E aqlvkdrn S MLRL T sigsde D E E T E TYQ EK VH mtwtkdkymasrgqkaksmegfqdl LNM R p 1076
Cdd:pfam03522 316 -- ELIEPF RL HEDDKEE E -------- S AEKI T ------ D S E L E ALK EK TN ------------------------- RQL R - 353
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 110224449 1077 dqsnvrrmhtavk L N E VIVNK S HE A K L VLLNM P G P PRNPEGDEN YM EF LE V LT EG L ERV LLVRG GGSE V I T I YS 1150
Cdd:pfam03522 354 ------------- L R E LLLEH S SD A N L IVMTL P M P RKGTVSAPL YM AW LE T LT KD L PPF LLVRG NQTS V L T F YS 414
AA_permease_2
pfam13520 Amino acid permease;
481-717
8.27e-15
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 78.12
E-value: 8.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 481 ITTS F TLLV G IFF p S V TG IMAGS N R S GDL K da QKSI P IGTILAILTTSFV Y - L S N VVL FG AC - IEGVV L RDKF G D --- AV 555
Cdd:pfam13520 187 WPGV F AGFL G VLW - S F TG FESAA N V S EEV K -- KRNV P KAIFIGVIIVGVL Y i L V N IAF FG VV p DDEIA L SSGL G Q vaa LL 263
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 556 KGNLVVGTLSW pspw VI VI GSFF S TC GA GLQSLT GA P RLL Q A I A K D NII PF L R V F GHSKAN G E P TW A LL LTA AIAELGI L 635
Cdd:pfam13520 264 FQAVGGKWGAI ---- IV VI LLAL S LL GA VNTAIV GA S RLL Y A L A R D GVL PF S R F F AKVNKF G S P IR A II LTA ILSLILL L 339
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 636 IAS L DLV A PI ---- LS MFFLMCYLFVNLACA L qt L LR TPNWRPRFRYYH W ALSFM G M s ICLALMFISSWYYAIVAMVIAG 711
Cdd:pfam13520 340 LFL L SPA A YN alls LS AYGYLLSYLLPIIGL L -- I LR KKRPDLGRIPGR W PVAIF G I - LFSLFLIVALFFPPVGPATGSS 416
....*.
gi 110224449 712 MI Y KY I 717
Cdd:pfam13520 417 LN Y AI I 422
2A0308
TIGR00911 L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
507-706
5.89e-05
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273332 [Multi-domain]
Cd Length: 501
Bit Score: 47.05
E-value: 5.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 507 GDL K DAQKSI PI GT I LAILTTS F V Y - L S N VVL F GACIEGVV L RDKFGDAVK G NLVV G TL SW PS P wv IVI G sf F S TC G AGL 585
Cdd:TIGR00911 259 EEV K NPYRTL PI AI I ISMPIVT F I Y v L T N IAY F TVLSPEEL L ASLAVAVDF G ERLL G VM SW AM P -- ALV G -- L S CF G SVN 334
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224449 586 Q SL TGAP RL LQAIAKDNII P F L RVFG H S K AN g E P TWA LL LTAAIAE L GILIASLDLVAPIL S MFF lmc Y LF VN LA C A LQT 665
Cdd:TIGR00911 335 G SL FSSS RL FFVGGREGHL P S L LSMI H V K RL - T P LPS LL IVCTLTL L MLFSGDIYSLINLI S FAN --- W LF NA LA V A GLL 410
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 110224449 666 L LR -- T P NWRPRFR yyhwalsfmg MSICLALM F IS S WYYA I VA 706
Cdd:TIGR00911 411 W LR yk R P EMNRPIK ---------- VPLFFPVF F LL S CLFL I IL 443
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
