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Conserved domains on  [gi|56549687|ref|NP_612494|]
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GTP-binding protein 8 isoform 2 [Homo sapiens]

Protein Classification

EngB GTPase family protein( domain architecture ID 10111617)

EngB GTPase family protein similar to GTP-binding protein 8 (GTPBP8) which belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily

CATH:  3.40.50.300
Gene Ontology:  GO:0046872|GO:0005525
SCOP:  4004043

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YihA_EngB cd01876
YihA (EngB) GTPase family; The YihA (EngB) subfamily of GTPases is typified by the E. coli ...
 113-247 2.12e-44

YihA (EngB) GTPase family; The YihA (EngB) subfamily of GTPases is typified by the E. coli YihA, an essential protein involved in cell division control. YihA and its orthologs are small proteins that typically contain less than 200 amino acid residues and consists of the GTPase domain only (some of the eukaryotic homologs contain an N-terminal extension of about 120 residues that might be involved in organellar targeting). Homologs of yihA are found in most Gram-positive and Gram-negative pathogenic bacteria, with the exception of Mycobacterium tuberculosis. The broad-spectrum nature of YihA and its essentiality for cell viability in bacteria make it an attractive antibacterial target.


:

Pssm-ID: 206665 [Multi-domain]  Cd Length: 170  Bit Score: 147.27  E-value: 2.12e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 113 GHTKKMNFFKVGKHFTVVDMPGYGF-RAP----EDFVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALP 187
Cdd:cd01876  33 GRTQLINFFNVGDKFRLVDLPGYGYaKVSkevrEKWGKLIEEYLENRENLKGVVLLIDARHGPTPIDLEMLEFLEELGIP 112

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 188 YVIVLTKIDKSSKGHLLKQVLQIQKFVNMKtqGCFPQLFPVSAVTFSGIHLLRCFIASVT 247
Cdd:cd01876 113 FLIVLTKADKLKKSELAKVLKKIKEELNLF--NILPPVILFSSKKGTGIDELRALIAEWL 170
 
Name Accession Description Interval E-value
YihA_EngB cd01876
YihA (EngB) GTPase family; The YihA (EngB) subfamily of GTPases is typified by the E. coli ...
 113-247 2.12e-44

YihA (EngB) GTPase family; The YihA (EngB) subfamily of GTPases is typified by the E. coli YihA, an essential protein involved in cell division control. YihA and its orthologs are small proteins that typically contain less than 200 amino acid residues and consists of the GTPase domain only (some of the eukaryotic homologs contain an N-terminal extension of about 120 residues that might be involved in organellar targeting). Homologs of yihA are found in most Gram-positive and Gram-negative pathogenic bacteria, with the exception of Mycobacterium tuberculosis. The broad-spectrum nature of YihA and its essentiality for cell viability in bacteria make it an attractive antibacterial target.


Pssm-ID: 206665 [Multi-domain]  Cd Length: 170  Bit Score: 147.27  E-value: 2.12e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 113 GHTKKMNFFKVGKHFTVVDMPGYGF-RAP----EDFVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALP 187
Cdd:cd01876  33 GRTQLINFFNVGDKFRLVDLPGYGYaKVSkevrEKWGKLIEEYLENRENLKGVVLLIDARHGPTPIDLEMLEFLEELGIP 112

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 188 YVIVLTKIDKSSKGHLLKQVLQIQKFVNMKtqGCFPQLFPVSAVTFSGIHLLRCFIASVT 247
Cdd:cd01876 113 FLIVLTKADKLKKSELAKVLKKIKEELNLF--NILPPVILFSSKKGTGIDELRALIAEWL 170
EngB COG0218
GTP-binding protein EngB required for normal cell division [Cell cycle control, cell division, ...
 91-245 7.60e-40

GTP-binding protein EngB required for normal cell division [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 439988 [Multi-domain]  Cd Length: 194  Bit Score: 136.36  E-value: 7.60e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687  91 NRIDYVSSAVRIDHAPDLPRPE-------------------------------GHTKKMNFFKVGKHFTVVDMPGYGF-R 138
Cdd:COG0218   4 KKAEFVTSAVKLEQLPPDDLPEiafagrsnvgksslinaltnrkklartsktpGKTQLINFFLINDKFYLVDLPGYGYaK 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 139 AP----EDFVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDKSSKGHLLKQVLQIQKFv 214
Cdd:COG0218  84 VSkaekEKWQKLIEDYLEGRENLKGVVLLIDIRHPPKELDLEMLEWLDEAGIPFLIVLTKADKLKKSELAKQLKAIKKA- 162

                       170       180       190
                ....*....|....*....|....*....|.
gi 56549687 215 nMKTQGCFPQLFPVSAVTFSGIHLLRCFIAS 245
Cdd:COG0218 163 -LGKDPAAPEVILFSSLKKEGIDELRAAIEE 192
GTPase_YsxC TIGR03598
ribosome biogenesis GTP-binding protein YsxC/EngB; Members of this protein family are a GTPase ...
 113-237 6.71e-35

ribosome biogenesis GTP-binding protein YsxC/EngB; Members of this protein family are a GTPase associated with ribosome biogenesis, typified by YsxC from Bacillus subutilis. The family is widely but not universally distributed among bacteria. Members commonly are called EngB based on homology to EngA, one of several other GTPases of ribosome biogenesis. Cutoffs as set find essentially all bacterial members, but also identify large numbers of eukaryotic (probably organellar) sequences. This protein is found in about 80 percent of bacterial genomes. [Protein synthesis, Other]


Pssm-ID: 274670 [Multi-domain]  Cd Length: 179  Bit Score: 122.97  E-value: 6.71e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687   113 GHTKKMNFFKVGKHFTVVDMPGYGF-RAPED----FVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALP 187
Cdd:TIGR03598  52 GRTQLINFFEVNDGFRLVDLPGYGYaKVSKEekekWQKLIEEYLEKRENLKGVVLLMDIRHPLKELDLEMIEWLRERGIP 131

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 56549687   188 YVIVLTKIDKSSKGHLLKQVLQIQKFVNMKTQGCFPQLFpvSAVTFSGIH 237
Cdd:TIGR03598 132 VLIVLTKADKLKKSELNKQLKKIKKALKKDADDPSVQLF--SSLKKTGID 179
MMR_HSR1 pfam01926
50S ribosome-binding GTPase; The full-length GTPase protein is required for the complete ...
 113-194 5.96e-08

50S ribosome-binding GTPase; The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.


Pssm-ID: 460387 [Multi-domain]  Cd Length: 113  Bit Score: 49.93  E-value: 5.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687   113 GHTKKMNFFKV---GKHFTVVDMPGYgFRAPEDFVDMVETYLKERRNlKRTFLLVDSVVGIQKTDNIAIEMCEEFALPYV 189
Cdd:pfam01926  31 GTTRDPNEGRLelkGKQIILVDTPGL-IEGASEGEGLGRAFLAIIEA-DLILFVVDSEEGITPLDEELLELLRENKKPII 108


                  ....*
gi 56549687   190 IVLTK 194
Cdd:pfam01926 109 LVLNK 113
era PRK00089
GTPase Era; Reviewed
 162-240 6.35e-05

GTPase Era; Reviewed


Pssm-ID: 234624 [Multi-domain]  Cd Length: 292  Bit Score: 43.11  E-value: 6.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687  162 LLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDK-SSKGHLLKQVLQIQKFVNmktqgcFPQLFPVSAVTFSGIHLLR 240
Cdd:PRK00089  90 FVVDADEKIGPGDEFILEKLKKVKTPVILVLNKIDLvKDKEELLPLLEELSELMD------FAEIVPISALKGDNVDELL 163
 
Name Accession Description Interval E-value
YihA_EngB cd01876
YihA (EngB) GTPase family; The YihA (EngB) subfamily of GTPases is typified by the E. coli ...
 113-247 2.12e-44

YihA (EngB) GTPase family; The YihA (EngB) subfamily of GTPases is typified by the E. coli YihA, an essential protein involved in cell division control. YihA and its orthologs are small proteins that typically contain less than 200 amino acid residues and consists of the GTPase domain only (some of the eukaryotic homologs contain an N-terminal extension of about 120 residues that might be involved in organellar targeting). Homologs of yihA are found in most Gram-positive and Gram-negative pathogenic bacteria, with the exception of Mycobacterium tuberculosis. The broad-spectrum nature of YihA and its essentiality for cell viability in bacteria make it an attractive antibacterial target.


Pssm-ID: 206665 [Multi-domain]  Cd Length: 170  Bit Score: 147.27  E-value: 2.12e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 113 GHTKKMNFFKVGKHFTVVDMPGYGF-RAP----EDFVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALP 187
Cdd:cd01876  33 GRTQLINFFNVGDKFRLVDLPGYGYaKVSkevrEKWGKLIEEYLENRENLKGVVLLIDARHGPTPIDLEMLEFLEELGIP 112

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 188 YVIVLTKIDKSSKGHLLKQVLQIQKFVNMKtqGCFPQLFPVSAVTFSGIHLLRCFIASVT 247
Cdd:cd01876 113 FLIVLTKADKLKKSELAKVLKKIKEELNLF--NILPPVILFSSKKGTGIDELRALIAEWL 170
EngB COG0218
GTP-binding protein EngB required for normal cell division [Cell cycle control, cell division, ...
 91-245 7.60e-40

GTP-binding protein EngB required for normal cell division [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 439988 [Multi-domain]  Cd Length: 194  Bit Score: 136.36  E-value: 7.60e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687  91 NRIDYVSSAVRIDHAPDLPRPE-------------------------------GHTKKMNFFKVGKHFTVVDMPGYGF-R 138
Cdd:COG0218   4 KKAEFVTSAVKLEQLPPDDLPEiafagrsnvgksslinaltnrkklartsktpGKTQLINFFLINDKFYLVDLPGYGYaK 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 139 AP----EDFVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDKSSKGHLLKQVLQIQKFv 214
Cdd:COG0218  84 VSkaekEKWQKLIEDYLEGRENLKGVVLLIDIRHPPKELDLEMLEWLDEAGIPFLIVLTKADKLKKSELAKQLKAIKKA- 162

                       170       180       190
                ....*....|....*....|....*....|.
gi 56549687 215 nMKTQGCFPQLFPVSAVTFSGIHLLRCFIAS 245
Cdd:COG0218 163 -LGKDPAAPEVILFSSLKKEGIDELRAAIEE 192
GTPase_YsxC TIGR03598
ribosome biogenesis GTP-binding protein YsxC/EngB; Members of this protein family are a GTPase ...
 113-237 6.71e-35

ribosome biogenesis GTP-binding protein YsxC/EngB; Members of this protein family are a GTPase associated with ribosome biogenesis, typified by YsxC from Bacillus subutilis. The family is widely but not universally distributed among bacteria. Members commonly are called EngB based on homology to EngA, one of several other GTPases of ribosome biogenesis. Cutoffs as set find essentially all bacterial members, but also identify large numbers of eukaryotic (probably organellar) sequences. This protein is found in about 80 percent of bacterial genomes. [Protein synthesis, Other]


Pssm-ID: 274670 [Multi-domain]  Cd Length: 179  Bit Score: 122.97  E-value: 6.71e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687   113 GHTKKMNFFKVGKHFTVVDMPGYGF-RAPED----FVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALP 187
Cdd:TIGR03598  52 GRTQLINFFEVNDGFRLVDLPGYGYaKVSKEekekWQKLIEEYLEKRENLKGVVLLMDIRHPLKELDLEMIEWLRERGIP 131

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 56549687   188 YVIVLTKIDKSSKGHLLKQVLQIQKFVNMKTQGCFPQLFpvSAVTFSGIH 237
Cdd:TIGR03598 132 VLIVLTKADKLKKSELNKQLKKIKKALKKDADDPSVQLF--SSLKKTGID 179
MMR_HSR1 pfam01926
50S ribosome-binding GTPase; The full-length GTPase protein is required for the complete ...
 113-194 5.96e-08

50S ribosome-binding GTPase; The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.


Pssm-ID: 460387 [Multi-domain]  Cd Length: 113  Bit Score: 49.93  E-value: 5.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687   113 GHTKKMNFFKV---GKHFTVVDMPGYgFRAPEDFVDMVETYLKERRNlKRTFLLVDSVVGIQKTDNIAIEMCEEFALPYV 189
Cdd:pfam01926  31 GTTRDPNEGRLelkGKQIILVDTPGL-IEGASEGEGLGRAFLAIIEA-DLILFVVDSEEGITPLDEELLELLRENKKPII 108


                  ....*
gi 56549687   190 IVLTK 194
Cdd:pfam01926 109 LVLNK 113
Era COG1159
GTPase Era, involved in 16S rRNA processing [Translation, ribosomal structure and biogenesis];
162-240 2.58e-06

GTPase Era, involved in 16S rRNA processing [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440773 [Multi-domain]  Cd Length: 290  Bit Score: 47.29  E-value: 2.58e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56549687 162 LLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDKSSKGHLLKQVLQIQKFVNmktqgcFPQLFPVSAVTFSGIHLLR 240
Cdd:COG1159  88 FVVDATEKIGEGDEFILELLKKLKTPVILVINKIDLVKKEELLPLLAEYSELLD------FAEIVPISALKGDNVDELL 160
Era cd04163
E. coli Ras-like protein (Era) is a multifunctional GTPase; Era (E. coli Ras-like protein) is ...
 162-240 2.77e-06

E. coli Ras-like protein (Era) is a multifunctional GTPase; Era (E. coli Ras-like protein) is a multifunctional GTPase found in all bacteria except some eubacteria. It binds to the 16S ribosomal RNA (rRNA) of the 30S subunit and appears to play a role in the assembly of the 30S subunit, possibly by chaperoning the 16S rRNA. It also contacts several assembly elements of the 30S subunit. Era couples cell growth with cytokinesis and plays a role in cell division and energy metabolism. Homologs have also been found in eukaryotes. Era contains two domains: the N-terminal GTPase domain and a C-terminal domain KH domain that is critical for RNA binding. Both domains are important for Era function. Era is functionally able to compensate for deletion of RbfA, a cold-shock adaptation protein that is required for efficient processing of the 16S rRNA.


Pssm-ID: 206726 [Multi-domain]  Cd Length: 168  Bit Score: 46.30  E-value: 2.77e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 162 LLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDK-SSKGHLLKQVLQIQKFVNmktqgcFPQLFPVSAVTFSGIHLLR 240
Cdd:cd04163  88 FVVDASEWIGEGDEFILELLKKSKTPVILVLNKIDLvKDKEDLLPLLEKLKELHP------FAEIFPISALKGENVDELL 161
era PRK00089
GTPase Era; Reviewed
 162-240 6.35e-05

GTPase Era; Reviewed


Pssm-ID: 234624 [Multi-domain]  Cd Length: 292  Bit Score: 43.11  E-value: 6.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687  162 LLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDK-SSKGHLLKQVLQIQKFVNmktqgcFPQLFPVSAVTFSGIHLLR 240
Cdd:PRK00089  90 FVVDADEKIGPGDEFILEKLKKVKTPVILVLNKIDLvKDKEELLPLLEELSELMD------FAEIVPISALKGDNVDELL 163
PRK04213 PRK04213
GTP-binding protein EngB;
110-197 7.00e-05

GTP-binding protein EngB;


Pssm-ID: 179790 [Multi-domain]  Cd Length: 201  Bit Score: 42.60  E-value: 7.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687  110 RPeGHTKKMNFFKVGKhFTVVDMPGYGFRA--PEDFVDMVET----YLKER-RNLKRTFLLVD--SVVGI----QKTDNI 176
Cdd:PRK04213  39 RP-GVTRKPNHYDWGD-FILTDLPGFGFMSgvPKEVQEKIKDeivrYIEDNaDRILAAVLVVDgkSFIEIierwEGRGEI 116

                         90       100
                 ....*....|....*....|....*.
gi 56549687  177 AI--EM---CEEFALPYVIVLTKIDK 197
Cdd:PRK04213 117 PIdvEMfdfLRELGIPPIVAVNKMDK 142
GTP_translation_factor cd00881
GTP translation factor family primarily contains translation initiation, elongation and ...
 118-239 2.09e-04

GTP translation factor family primarily contains translation initiation, elongation and release factors; The GTP translation factor family consists primarily of translation initiation, elongation, and release factors, which play specific roles in protein translation. In addition, the family includes Snu114p, a component of the U5 small nuclear riboprotein particle which is a component of the spliceosome and is involved in excision of introns, TetM, a tetracycline resistance gene that protects the ribosome from tetracycline binding, and the unusual subfamily CysN/ATPS, which has an unrelated function (ATP sulfurylase) acquired through lateral transfer of the EF1-alpha gene and development of a new function.


Pssm-ID: 206647 [Multi-domain]  Cd Length: 183  Bit Score: 41.13  E-value: 2.09e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 118 MNFFKVGKHFTVVDMPGYgfrapEDFVDMVETYLkerRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALPYVIVLTKIDK 197
Cdd:cd00881  55 VEFEWPKRRINFIDTPGH-----EDFSKETVRGL---AQADGALLVVDANEGVEPQTREHLNIALAGGLPIIVAVNKIDR 126

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 56549687 198 SSKGHLLKQVLQIQKFVN----MKTQGCFPQLFPVSAVTFSGIHLL 239
Cdd:cd00881 127 VGEEDFDEVLREIKELLKligfTFLKGKDVPIIPISALTGEGIEEL 172
Ras_like_GTPase cd00882
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like ...
 103-236 8.71e-04

Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras, Rho, Rab, and Sar1/Arf families. This superfamily also includes proteins like the GTP translation factors, Era-like GTPases, and G-alpha chain of the heterotrimeric G proteins. Members of the Ras superfamily regulate a wide variety of cellular functions: the Ras family regulates gene expression, the Rho family regulates cytoskeletal reorganization and gene expression, the Rab and Sar1/Arf families regulate vesicle trafficking, and the Ran family regulates nucleocytoplasmic transport and microtubule organization. The GTP translation factor family regulates initiation, elongation, termination, and release in translation, and the Era-like GTPase family regulates cell division, sporulation, and DNA replication. Members of the Ras superfamily are identified by the GTP binding site, which is made up of five characteristic sequence motifs, and the switch I and switch II regions.


Pssm-ID: 206648 [Multi-domain]  Cd Length: 161  Bit Score: 38.98  E-value: 8.71e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549687 103 DHAPDLPRPEGHTKKMNFFKVGKH-----FTVVDMPGYGFRAPEDFVDMVETYLKERRNLkrtFLLVDSVVG--IQKTDN 175
Cdd:cd00882  20 GEVGEVSDVPGTTRDPDVYVKELDkgkvkLVLVDTPGLDEFGGLGREELARLLLRGADLI---LLVVDSTDResEEDAKL 96

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56549687 176 IAIEMCEEFALPYVIVLTKIDKSSKGHLLKQVLQIQKFvnmktQGCFPQLFPVSAVTFSGI 236
Cdd:cd00882  97 LILRRLRKEGIPIILVGNKIDLLEEREVEELLRLEELA-----KILGVPVFEVSAKTGEGV 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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