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Conserved domains on  [gi|56549645|ref|NP_624358|]
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nuclear pore complex protein Nup98-Nup96 isoform 4 [Homo sapiens]

Protein Classification

Nucleoporin2 and Nup96 domain-containing protein( domain architecture ID 13837623)

protein containing domains Herpes_BLLF1, Nucleoporin_FG, Nucleoporin2, and Nup96

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1315-1532 3.92e-82

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


:

Pssm-ID: 463462  Cd Length: 287  Bit Score: 271.78  E-value: 3.92e-82
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1315 EAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLS 1394
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1395 EKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQntsdSDRYACSPLPSYLEGSGCVIAEEQNSQTPLrDV 1474
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALS----QGREPAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1475 CFHLLKLYSD---------------------------------------------------------------------- 1484
Cdd:pfam12110  156 LYHLLKLYADptapleavldpessspdpldyrlswhlyqvlsavrlgyghlssakadqltlsfasqleslglwqwavfvl 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 56549645   1485 ------SIREKAVRELLTRHCQLLETPESwaKETFLTQKLRVPAKWIHEAKAVR 1532
Cdd:pfam12110  236 lhledpARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 721-863 2.49e-63

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


:

Pssm-ID: 461171  Cd Length: 143  Bit Score: 211.97  E-value: 2.49e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    721 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVVVYLDDNQKPPVGE 796
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56549645    797 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 863
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 25-435 7.54e-16

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


:

Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 83.67  E-value: 7.54e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG4625   74 AGGGGGGGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGG 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG4625  154 GGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGG 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  185 KHQCITAMkeYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG4625  234 GGGGGGGG--GGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGG 311

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG4625  312 GGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGG 391

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTAL 424
Cdd:COG4625  392 GGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGS 471

                        410
                 ....*....|.
gi 56549645  425 GAGQASLFGNN 435
Cdd:COG4625  472 GAGTLTLTGNN 482
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 243-666 3.01e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 45.68  E-value: 3.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    243 SSTTNSGFAYGQNKTaFGTSTTGFGTNPGGLFGQQNQQTTSlfskpfgqaTTTQNTGFSFGNTSTIGQPSTNTMGlfgvt 322
Cdd:pfam05109  374 SGCENISGAFASNRT-FDITVSGLGTAPKTLIITRTATNAT---------TTTHKVIFSKAPESTTTSPTLNTTG----- 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    323 qasqpgglfgtatntstgtafgtgtglFGQTNTGFGAVGSTLFGNNkLTTFGSSTTSAPSFGTTSGGLFGfgtNTSGNSI 402
Cdd:pfam05109  439 ---------------------------FAAPNTTTGLPSSTHVPTN-LTAPASTGPTVSTADVTSPTPAG---TTSGASP 487

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    403 FGSKPAPGTLGTGLGAGFGTAlgagQASLFGNNQPKIGGPlgTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQA 482
Cdd:pfam05109  488 VTPSPSPRDNGTESKAPDMTS----PTSAVTTPTPNATSP--TPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPA 561

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    483 VLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKalTTPTHYKLTPRPATRVRPKALQTTGTAKSHlfdgl 562
Cdd:pfam05109  562 VTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANT--TNHTLGGTSSTPVVTSPPKNATSAVTTGQH----- 634

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    563 dddepslangaFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASP---SEYPENGERFSFLSKPVDENHqqdgdedslvs 639
Cdd:pfam05109  635 -----------NITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPlltSAHPTGGENITQVTPASTSTH----------- 692

                          410       420
                   ....*....|....*....|....*..
gi 56549645    640 HFYTNPIAkPIPQTPESAGNKHSNSNS 666
Cdd:pfam05109  693 HVSTSSPA-PRPGTTSQASGPGNSSTS 718
 
Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1315-1532 3.92e-82

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


Pssm-ID: 463462  Cd Length: 287  Bit Score: 271.78  E-value: 3.92e-82
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1315 EAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLS 1394
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1395 EKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQntsdSDRYACSPLPSYLEGSGCVIAEEQNSQTPLrDV 1474
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALS----QGREPAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1475 CFHLLKLYSD---------------------------------------------------------------------- 1484
Cdd:pfam12110  156 LYHLLKLYADptapleavldpessspdpldyrlswhlyqvlsavrlgyghlssakadqltlsfasqleslglwqwavfvl 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 56549645   1485 ------SIREKAVRELLTRHCQLLETPESwaKETFLTQKLRVPAKWIHEAKAVR 1532
Cdd:pfam12110  236 lhledpARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 721-863 2.49e-63

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


Pssm-ID: 461171  Cd Length: 143  Bit Score: 211.97  E-value: 2.49e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    721 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVVVYLDDNQKPPVGE 796
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56549645    797 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 863
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 25-435 7.54e-16

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 83.67  E-value: 7.54e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG4625   74 AGGGGGGGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGG 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG4625  154 GGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGG 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  185 KHQCITAMkeYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG4625  234 GGGGGGGG--GGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGG 311

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG4625  312 GGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGG 391

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTAL 424
Cdd:COG4625  392 GGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGS 471

                        410
                 ....*....|.
gi 56549645  425 GAGQASLFGNN 435
Cdd:COG4625  472 GAGTLTLTGNN 482
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 40-149 2.89e-13

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 66.87  E-value: 2.89e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645     40 SAFGSSNNT-GGLFGNSQTKP---GGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTslfssqnnafaqnkpt 115
Cdd:pfam13634    1 GLFGAATSTsGGLFGNTSTTAasgGGLFGAASTATATTSGGGLFGNSSSNAPSGGLFGATNTTT---------------- 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 56549645    116 gfgnfgTSTSSGGLFGTTNTTSNPfgSTSGSLFG 149
Cdd:pfam13634   65 ------QTATGGGLFGNNAATTTS--TTGGGLFG 90
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 25-334 6.24e-10

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 64.26  E-value: 6.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    25 QNTGFGTTSGGAFGTS-AFGSSNNTGGLFGNSQTKPGGL---FGTSSFSQPATSTSTGFGFGTSTGTantlfgtaSTGTS 100
Cdd:NF033849  255 QSHSVGTSESHSVGTSqSQSHTTGHGSTRGWSHTQSTSEsesTGQSSSVGTSESQSHGTTEGTSTTD--------SSSHS 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   101 LFSSQNNAFAQnkptgfgNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
Cdd:NF033849  327 QSSSYNVSSGT-------GVSSSHSDGTSQSTSISHSESSSESTGTSVGHSTSSSVSSSESSSRSSSSGVSGGFSGGIAG 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   181 NISTKHQCITAMKEYESKSLEelrlEDYQANRKGPQNQVGAGTTTglfGSSPATSSATGLFSSSTTNSGFAYGQNKTAfg 260
Cdd:NF033849  400 GGVTSEGLGASQGGSEGWGSG----DSVQSVSQSYGSSSSTGTSS---GHSDSSSHSTSSGQADSVSQGTSWSEGTGT-- 470

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56549645   261 TSTTGFGTNPGglFGQQNQQTTSlFSKPFGQATTT-QNTGFSFGNTSTIGQPSTNTMGlfgvtQASQPGGLFGTA 334
Cdd:NF033849  471 SQGQSVGTSES--WSTSQSETDS-VGDSTGTSESVsQGDGRSTGRSESQGTSLGTSGG-----RTSGAGGSMGLG 537
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
33-403 1.64e-05

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 50.04  E-value: 1.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    33 SGGAFGTSAFGSSNNTGGLFGNSQTK-PGGLFGTSSFSQPATS--TSTGFGFGT---STGTANTLFGTASTGTSLFSSQN 106
Cdd:NF033176  139 SGGAQNIYNLGHASNTVIFNGGNQTIfSGGISDDTNISSGGQQrvSSGGVASNTtinSSGTQNILSGGSTVSTHISSGGN 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   107 N-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAaptGTTIKFNPPTGTDTMVKAGVSTN 181
Cdd:NF033176  219 QyisagGNASATVVSSGGFQRVSSGGTATGTVLSGGTQNVSSGGSAISTSVYSS---GVQTVYAGATVTDTTVNSGGKQN 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSS--ATGLFSSSTTNSGfayGQNKTAF 259
Cdd:NF033176  296 ISSGGIVSGTIVNSSGTQNIYSGGSALSANIKGSQIVNSDGTAINTLVNDGGYQHirNGGVASGTIINQS---GRVNISS 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   260 GTSTTGFGTNPGGlfgqqnqqTTSLFSKPFGQATTTQNTGFSfgNTSTiGQPSTNTMGLFGVTQASQPGGlfgTATNTST 339
Cdd:NF033176  373 GGYAESTIINSGG--------TQSVLSGGYASGTLINNSGRE--NVSN-GGSAYNTIINAGGNQYIYSNG---EASGTTV 438

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56549645   340 GTAFgtgtglFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGfGTNTSGNSIF 403
Cdd:NF033176  439 NTSG------FQRVNSGGTATGTKLSGGNQNVSSGGKAIAAEVYSGGKQTVYA-GGEASGTQIF 495
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 243-666 3.01e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 45.68  E-value: 3.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    243 SSTTNSGFAYGQNKTaFGTSTTGFGTNPGGLFGQQNQQTTSlfskpfgqaTTTQNTGFSFGNTSTIGQPSTNTMGlfgvt 322
Cdd:pfam05109  374 SGCENISGAFASNRT-FDITVSGLGTAPKTLIITRTATNAT---------TTTHKVIFSKAPESTTTSPTLNTTG----- 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    323 qasqpgglfgtatntstgtafgtgtglFGQTNTGFGAVGSTLFGNNkLTTFGSSTTSAPSFGTTSGGLFGfgtNTSGNSI 402
Cdd:pfam05109  439 ---------------------------FAAPNTTTGLPSSTHVPTN-LTAPASTGPTVSTADVTSPTPAG---TTSGASP 487

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    403 FGSKPAPGTLGTGLGAGFGTAlgagQASLFGNNQPKIGGPlgTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQA 482
Cdd:pfam05109  488 VTPSPSPRDNGTESKAPDMTS----PTSAVTTPTPNATSP--TPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPA 561

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    483 VLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKalTTPTHYKLTPRPATRVRPKALQTTGTAKSHlfdgl 562
Cdd:pfam05109  562 VTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANT--TNHTLGGTSSTPVVTSPPKNATSAVTTGQH----- 634

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    563 dddepslangaFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASP---SEYPENGERFSFLSKPVDENHqqdgdedslvs 639
Cdd:pfam05109  635 -----------NITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPlltSAHPTGGENITQVTPASTSTH----------- 692

                          410       420
                   ....*....|....*....|....*..
gi 56549645    640 HFYTNPIAkPIPQTPESAGNKHSNSNS 666
Cdd:pfam05109  693 HVSTSSPA-PRPGTTSQASGPGNSSTS 718
34 PHA02584
long tail fiber, proximal subunit; Provisional
 25-175 3.04e-03

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 42.43  E-value: 3.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    25 QNTGFGTTSGGAFGTSAFGSSNNTGG---------------------------LFGNSQTKPGGlfGTSSFSQPATSTST 77
Cdd:PHA02584  944 QNTSNGTVVVVDETSIAFYSQNNTTGnivfnidgtvdpinvnangtlnatgvaTNGRAVYAEGG--GIARTNNAARAITG 1021

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    78 GFGFGTSTGTANTLFGTASTGTSLFSSQ-----NNAFAQNK--PTGFGNFGTSTSSGGLfgttnTTSNPFGSTSGSlfgp 150
Cdd:PHA02584 1022 GFTIRNDGSTTVFLLTAAGDQTGGFNGLksliiNNANGQVTinDNYIINAGGTIMSGGL-----TVNSRIRSQGTK---- 1092

                         170       180
                  ....*....|....*....|....*
gi 56549645   151 SSFTAAPTGTTIKFNPPTGTDTMVK 175
Cdd:PHA02584 1093 ASYTRAPTADTVGFWSVDINDSATY 1117
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 25-152 4.33e-03

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 41.52  E-value: 4.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NSQ--------------------TKPGGLFGTSSFSQPATSTSTG 78
Cdd:cd21118  145 GGTGGPWASGGNYGTNSLGGSVGQGGNGGplnygtNSQgavaqpgygtvrgnnqnsgcTNPPPSGSHESFSNSGGSSSSG 224

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56549645   79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLFG-TTNTTSNPFGSTSGSLFGPSS 152
Cdd:cd21118  225 SSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSgNSGGSNGGSSGNSGSGSGgSSSGGSNGWGGSSSSGGSGGS 300
 
Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1315-1532 3.92e-82

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


Pssm-ID: 463462  Cd Length: 287  Bit Score: 271.78  E-value: 3.92e-82
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1315 EAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLS 1394
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1395 EKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQntsdSDRYACSPLPSYLEGSGCVIAEEQNSQTPLrDV 1474
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALS----QGREPAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   1475 CFHLLKLYSD---------------------------------------------------------------------- 1484
Cdd:pfam12110  156 LYHLLKLYADptapleavldpessspdpldyrlswhlyqvlsavrlgyghlssakadqltlsfasqleslglwqwavfvl 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 56549645   1485 ------SIREKAVRELLTRHCQLLETPESwaKETFLTQKLRVPAKWIHEAKAVR 1532
Cdd:pfam12110  236 lhledpARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 721-863 2.49e-63

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


Pssm-ID: 461171  Cd Length: 143  Bit Score: 211.97  E-value: 2.49e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    721 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVVVYLDDNQKPPVGE 796
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56549645    797 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 863
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 25-435 7.54e-16

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 83.67  E-value: 7.54e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG4625   74 AGGGGGGGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGG 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG4625  154 GGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGG 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  185 KHQCITAMkeYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG4625  234 GGGGGGGG--GGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGG 311

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG4625  312 GGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGG 391

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTAL 424
Cdd:COG4625  392 GGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGS 471

                        410
                 ....*....|.
gi 56549645  425 GAGQASLFGNN 435
Cdd:COG4625  472 GAGTLTLTGNN 482
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 40-149 2.89e-13

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 66.87  E-value: 2.89e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645     40 SAFGSSNNT-GGLFGNSQTKP---GGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTslfssqnnafaqnkpt 115
Cdd:pfam13634    1 GLFGAATSTsGGLFGNTSTTAasgGGLFGAASTATATTSGGGLFGNSSSNAPSGGLFGATNTTT---------------- 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 56549645    116 gfgnfgTSTSSGGLFGTTNTTSNPfgSTSGSLFG 149
Cdd:pfam13634   65 ------QTATGGGLFGNNAATTTS--TTGGGLFG 90
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 24-492 3.14e-13

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 75.57  E-value: 3.14e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   24 GQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFS 103
Cdd:COG3210  825 TATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTN 904

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  104 SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
Cdd:COG3210  905 AASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSA 984

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  184 TKHQCIT-AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS 262
Cdd:COG3210  985 GSTGGVIaATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTAS 1064

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  263 TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA 342
Cdd:COG3210 1065 GTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGT 1144

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  343 FGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGT 422
Cdd:COG3210 1145 LTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTA 1224

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  423 ALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLT 492
Cdd:COG3210 1225 SDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATATGSTVDIGSTSAT 1294
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 239-332 5.61e-13

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 66.10  E-value: 5.61e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    239 GLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNpgglfgqQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTiGQPSTNTMGL 318
Cdd:pfam13634    1 GLFGAATSTSGGLFGNTSTTAASGGGLFGAA-------STATATTSGGGLFGNSSSNAPSGGLFGATNT-TTQTATGGGL 72

                           90
                   ....*....|....*...
gi 56549645    319 FGVTQASQP----GGLFG 332
Cdd:pfam13634   73 FGNNAATTTsttgGGLFG 90
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 25-464 6.36e-12

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 71.34  E-value: 6.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG3210  297 TNGTSSVTGAGGTGVLGGGTAAGITTTNTVGGNGDGNNTTANSGAGLVSGGTGGNNGTTGTGAGSGLTGTGNGGGLTTAG 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG3210  377 AGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGNGTVTGGTIGGLTGSGTTN 456

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  185 KHQCITAmkeyesksleelrledyqANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTA----FG 260
Cdd:COG3210  457 GAGLSGN------------------TDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATgltgIT 518

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  261 TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTG 340
Cdd:COG3210  519 AGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGG 598

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  341 TAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
Cdd:COG3210  599 TVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTV 678

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....
gi 56549645  421 GTALGAGQASLFGNNQpKIGGPLGTGAFGAPGFNTTTATLGFGA 464
Cdd:COG3210  679 TSGATGGTTGTTLNAA-TGGTLNNAGNTLTISTGSITVTGQIGA 721
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 44-273 1.17e-11

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 69.70  E-value: 1.17e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645     44 SSNNTGGLFGNSQTKPGGL-FGTSSFSQPatSTSTGFGFGTSTGTANtlfGTASTGTSLFSSQNNAFAQNKPTGFGnfgt 122
Cdd:pfam15967    2 SGFSFGGGPGSTATAGGGFsFGAAAASNP--GSTGGFSFGTLGAAPA---ATATTTTATLGLGGGLFGQKPATGFT---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    123 stssgglFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMkeyeskslee 202
Cdd:pfam15967   73 -------FGTPASSTAATGPTGLTLGTPAATTAASTGFSLGFNKPAASATPFSLPASSTSGGGLSLGSVL---------- 135

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56549645    203 lrledyqanrKGPQNQVGAGTTTGLFGSSPATSSA--TGLFSSSTTNS-GFAYGQNktafgTSTTGFGTNPGGL 273
Cdd:pfam15967  136 ----------TSTAAQQGATGFTLNLGGTPATTTAvsTGLSLGSTLTSlGGSLFQN-----TNSTGLGQTTLGL 194
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 25-402 1.20e-11

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 70.18  E-value: 1.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG3210  368 NGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGNGTVTGGTIG 447

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG3210  448 GLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGGNA 527

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  185 KHQCITAmkeyesksleelrledYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG3210  528 TSGGTGG----------------DGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGG 591

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG3210  592 TGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTG 671

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 56549645  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT-TSGGLFGFGTNTSGNSI 402
Cdd:COG3210  672 GGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSiTVTGQIGALANANGDTV 730
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 272-392 4.05e-11

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 60.71  E-value: 4.05e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    272 GLFGQQNQQTTSLFSkpfGQATTTQNTGFSFGNTSTiGQPSTNTMGLFGVTQASQP-GGLFGTatntstgtafgtgtglf 350
Cdd:pfam13634    1 GLFGAATSTSGGLFG---NTSTTAASGGGLFGAAST-ATATTSGGGLFGNSSSNAPsGGLFGA----------------- 59

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 56549645    351 gQTNTGFGAVGSTLFGNNklttfgssttSAPSFGTTSGGLFG 392
Cdd:pfam13634   60 -TNTTTQTATGGGLFGNN----------AATTTSTTGGGLFG 90
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 25-334 6.24e-10

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 64.26  E-value: 6.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    25 QNTGFGTTSGGAFGTS-AFGSSNNTGGLFGNSQTKPGGL---FGTSSFSQPATSTSTGFGFGTSTGTantlfgtaSTGTS 100
Cdd:NF033849  255 QSHSVGTSESHSVGTSqSQSHTTGHGSTRGWSHTQSTSEsesTGQSSSVGTSESQSHGTTEGTSTTD--------SSSHS 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   101 LFSSQNNAFAQnkptgfgNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
Cdd:NF033849  327 QSSSYNVSSGT-------GVSSSHSDGTSQSTSISHSESSSESTGTSVGHSTSSSVSSSESSSRSSSSGVSGGFSGGIAG 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   181 NISTKHQCITAMKEYESKSLEelrlEDYQANRKGPQNQVGAGTTTglfGSSPATSSATGLFSSSTTNSGFAYGQNKTAfg 260
Cdd:NF033849  400 GGVTSEGLGASQGGSEGWGSG----DSVQSVSQSYGSSSSTGTSS---GHSDSSSHSTSSGQADSVSQGTSWSEGTGT-- 470

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56549645   261 TSTTGFGTNPGglFGQQNQQTTSlFSKPFGQATTT-QNTGFSFGNTSTIGQPSTNTMGlfgvtQASQPGGLFGTA 334
Cdd:NF033849  471 SQGQSVGTSES--WSTSQSETDS-VGDSTGTSESVsQGDGRSTGRSESQGTSLGTSGG-----RTSGAGGSMGLG 537
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 26-464 1.13e-09

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 63.63  E-value: 1.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG3210  625 ANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGN 704

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  106 NNAFAQNKPTGFGNFGTSTSSGG--------LFGTTNTTSNPFGSTSGSLFGPSSFTAAP---TGTTIKFNPPTGTDTmV 174
Cdd:COG3210  705 TLTISTGSITVTGQIGALANANGdtvtfgnlGTGATLTLNAGVTITSGNAGTLSIGLTANttaSGTTLTLANANGNTS-A 783

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  175 KAGVSTNISTKHQCITAmkeyesksleelrleDYQANRKGPqNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254
Cdd:COG3210  784 GATLDNAGAEISIDITA---------------DGTITAAGT-TAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTD 847

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTA 334
Cdd:COG3210  848 TTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLT 927

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  335 TNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
Cdd:COG3210  928 GGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTAS 1007

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|
gi 56549645  415 GLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGA 464
Cdd:COG3210 1008 TTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGN 1057
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 26-492 2.23e-09

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 62.49  E-value: 2.23e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG4625  173 GGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGG 252

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  106 NNAFAQNkpTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTk 185
Cdd:COG4625  253 GGGGGNG--GGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  186 hqcitamkeyesksleelrledYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTG 265
Cdd:COG4625  330 ----------------------GGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGG 387

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  266 FGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG------FSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTST 339
Cdd:COG4625  388 SGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGgggggtGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGG 467

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  340 GTAFGTGTGLFGQTNTGFGAVGSTLFGNNkltTFGSSTTSAPSFGTTSGGLfgfgTNTSGN-SIFGSKPAPGTLGTGLGA 418
Cdd:COG4625  468 GSGSGAGTLTLTGNNTYTGTTTVNGGGNY---TQSAGSTLAVEVDAANSDR----LVVTGTaTLNGGTVVVLAGGYAPGT 540

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56549645  419 GFgTALGAGQAslfgnnqpkiggpLGTGAFGAPGFNTTTATLGFGAPQAPVALTD--PNASAAQQAVLQQHINSLT 492
Cdd:COG4625  541 TY-TILAVAAA-------------LDALAGNGDLSALYNALAALDAAAARAALDQlsGEIHASAAAALLQASRALR 602
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 25-93 5.75e-08

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 51.85  E-value: 5.75e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56549645     25 QNTGFGTTSGGAFGTSAFGSSNNTGG-LFGNSQTKP--GGLFGTSSFSQPATSTSTGFGFGTSTGTANT---LFG 93
Cdd:pfam13634   16 NTSTTAASGGGLFGAASTATATTSGGgLFGNSSSNApsGGLFGATNTTTQTATGGGLFGNNAATTTSTTgggLFG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 90-161 2.08e-07

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 50.31  E-value: 2.08e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645     90 TLFGTA-STGTSLFSSQNNAF------------AQNKPTGFGNFG---TSTSSGGLFGTTNTTSNPfgSTSGSLFGPSSF 153
Cdd:pfam13634    1 GLFGAAtSTSGGLFGNTSTTAasggglfgaastATATTSGGGLFGnssSNAPSGGLFGATNTTTQT--ATGGGLFGNNAA 78


                   ....*...
gi 56549645    154 TAAPTGTT 161
Cdd:pfam13634   79 TTTSTTGG 86
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 363-463 1.20e-06

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 48.00  E-value: 1.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    363 TLFGNNKLTT---FGSSTTSApsfgTTSGGLFGFG----TNTSGNSIFGSKPAPgtlgtglgagfgtalgAGQASLFGNN 435
Cdd:pfam13634    1 GLFGAATSTSgglFGNTSTTA----ASGGGLFGAAstatATTSGGGLFGNSSSN----------------APSGGLFGAT 60

                           90       100       110
                   ....*....|....*....|....*....|
gi 56549645    436 QPKIGGPLGTGAFGAPGFNTTTATLG--FG 463
Cdd:pfam13634   61 NTTTQTATGGGLFGNNAATTTSTTGGglFG 90
Hia COG5295
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ...
 26-402 1.49e-06

Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444098 [Multi-domain]  Cd Length: 785  Bit Score: 53.24  E-value: 1.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG5295  219 ASVGVNAGAATGSAASAGGSASAGAASGNATTASASSVSGSAVAAGTASTATTASTTAASGAAGTATAAAGGDAAAAGSA 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185
Cdd:COG5295  299 SSTGAANATAGGGNAGSGGGGAAALGSAGGSSGVGTASGASAAAATNDGTANGAGTSAAADATSGGGAGGGGAAATSSSG 378

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  186 hqcitamkeyesksleelrLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTG 265
Cdd:COG5295  379 -------------------GSATAAGNAAGAAGAGSAGSGGSSTGASAGGGASAAGGAAAGSAAAGTSSNTSAVGASNGA 439

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  266 FGTNpGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGT 345
Cdd:COG5295  440 SGTS-SSASSAGAAGGGTAGAGGAANVGAATTAASAAATAAAATSSAAIAGATATGAGAAAGGAGAGAAGGAGSAAAGGA 518

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 56549645  346 GTGLFGQTNTGFGAVGSTLFGNnklTTFGSSTTSAPSFGTTSgglFGFGTNTSGNSI 402
Cdd:COG5295  519 ANAAAASGATATAGSAGGGAAA---AAGGGSTTAATGTNSVA---VGNNTATGANSV 569
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 309-404 1.91e-06

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 47.61  E-value: 1.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    309 GQPSTNTMGLFG--VTQASQPGGLFGTATNTstgtafgtgtglfGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPsfGTT 386
Cdd:pfam13634    4 GAATSTSGGLFGntSTTAASGGGLFGAASTA-------------TATTSGGGLFGNSSSNAPSGGLFGATNTTTQ--TAT 68

                           90       100
                   ....*....|....*....|..
gi 56549645    387 SGGLFG----FGTNTSGNSIFG 404
Cdd:pfam13634   69 GGGLFGnnaaTTTSTTGGGLFG 90
PPE COG5651
PPE-repeat protein [Function unknown];
31-183 2.60e-06

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 51.82  E-value: 2.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   31 TTSGGAFGTSAFGSSNN-------TGGLFGNSQTKPGGL-FGTSSFSQPATSTSTGFgFGTSTGTANTLFGTASTGTSLF 102
Cdd:COG5651  175 TNPGGLLGAQNAGSGNTssnpgfaNLGLTGLNQVGIGGLnSGSGPIGLNSGPGNTGF-AGTGAAAGAAAAAAAAAAAAGA 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  103 SSQNN-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177
Cdd:COG5651  254 GASAAlaslaATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAA 333


                 ....*.
gi 56549645  178 VSTNIS 183
Cdd:COG5651  334 AAAAGA 339
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 26-335 3.40e-06

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 52.26  E-value: 3.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLF--- 102
Cdd:COG3468  100 GTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGTGSGGGGSGGGGGAGGggg 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  103 -----SSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177
Cdd:COG3468  180 ggaggSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGGGGSAGGTGGGGLTGGGAA 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  178 VSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPA---TSSATGLFSSSTTNSGFAYGQ 254
Cdd:COG3468  260 GTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGgggGSNAGGGSGGGGGGGGGGGGG 339

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  255 NKTA--FGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFG 332
Cdd:COG3468  340 GTTLngAGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTGNNGGGGVGGGGGGGLTLT 419


                 ...
gi 56549645  333 TAT 335
Cdd:COG3468  420 GGT 422
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 33-182 3.84e-06

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 51.59  E-value: 3.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645     33 SGGAFGTSAFGSSNNTGGL-FGNSQTKP----GGL-FGTSSFSQPATSTST-----------------GFGFGT------ 83
Cdd:pfam15967    2 SGFSFGGGPGSTATAGGGFsFGAAAASNpgstGGFsFGTLGAAPAATATTTtatlglggglfgqkpatGFTFGTpassta 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645     84 STGTANTLFGTASTGTSlfSSQNNAFAQNKPTG----FGNFGTSTSSGGL-FGTTNTTSNPFGSTSGSLFG----PSSFT 154
Cdd:pfam15967   82 ATGPTGLTLGTPAATTA--ASTGFSLGFNKPAAsatpFSLPASSTSGGGLsLGSVLTSTAAQQGATGFTLNlggtPATTT 159

                          170       180
                   ....*....|....*....|....*...
gi 56549645    155 AAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
Cdd:pfam15967  160 AVSTGLSLGSTLTSLGGSLFQNTNSTGL 187
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 26-309 4.17e-06

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 51.87  E-value: 4.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG3468  142 GGGGGTGVGGTGAAAAGGGTGSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGA 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIkfNPPTGTDTMVKAGVSTNISTK 185
Cdd:COG3468  222 GGATGGAGSGGNTGGGVGGGGGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGG--GANGGGSGGGGGASGTGGGGT 299

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  186 HQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTG 265
Cdd:COG3468  300 ASTGGGGGGGGGNGGGGGGGSNAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGA 379

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 56549645  266 FGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN---TGFSFGNTSTIG 309
Cdd:COG3468  380 GGGGANTGSDGVGTGLTTGGTGNNGGGGVGGGgggGLTLTGGTLTVN 426
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 216-320 7.88e-06

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 45.68  E-value: 7.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    216 QNQVGAGTTTGLFGSSPATSSATGLFSSsttnsgfaygqnktaFGTSTTgfGTNPGGLFGQQNQQttslfskpfgqaTTT 295
Cdd:pfam13634   16 NTSTTAASGGGLFGAASTATATTSGGGL---------------FGNSSS--NAPSGGLFGATNTT------------TQT 66

                           90       100
                   ....*....|....*....|....*
gi 56549645    296 QNTGFSFGNTSTIGQPSTNTmGLFG 320
Cdd:pfam13634   67 ATGGGLFGNNAATTTSTTGG-GLFG 90
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
33-403 1.64e-05

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 50.04  E-value: 1.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    33 SGGAFGTSAFGSSNNTGGLFGNSQTK-PGGLFGTSSFSQPATS--TSTGFGFGT---STGTANTLFGTASTGTSLFSSQN 106
Cdd:NF033176  139 SGGAQNIYNLGHASNTVIFNGGNQTIfSGGISDDTNISSGGQQrvSSGGVASNTtinSSGTQNILSGGSTVSTHISSGGN 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   107 N-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAaptGTTIKFNPPTGTDTMVKAGVSTN 181
Cdd:NF033176  219 QyisagGNASATVVSSGGFQRVSSGGTATGTVLSGGTQNVSSGGSAISTSVYSS---GVQTVYAGATVTDTTVNSGGKQN 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSS--ATGLFSSSTTNSGfayGQNKTAF 259
Cdd:NF033176  296 ISSGGIVSGTIVNSSGTQNIYSGGSALSANIKGSQIVNSDGTAINTLVNDGGYQHirNGGVASGTIINQS---GRVNISS 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   260 GTSTTGFGTNPGGlfgqqnqqTTSLFSKPFGQATTTQNTGFSfgNTSTiGQPSTNTMGLFGVTQASQPGGlfgTATNTST 339
Cdd:NF033176  373 GGYAESTIINSGG--------TQSVLSGGYASGTLINNSGRE--NVSN-GGSAYNTIINAGGNQYIYSNG---EASGTTV 438

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56549645   340 GTAFgtgtglFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGfGTNTSGNSIF 403
Cdd:NF033176  439 NTSG------FQRVNSGGTATGTKLSGGNQNVSSGGKAIAAEVYSGGKQTVYA-GGEASGTQIF 495
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
26-172 3.94e-05

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 48.21  E-value: 3.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTST----------GTANTLFGTA 95
Cdd:COG3469   52 AASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVATSTASGANTGTSTvtttstgagsVTSTTSSTAG 131

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56549645   96 STGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGlfgTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT 172
Cdd:COG3469  132 STTTSGASATSSAGSTTTTTTVSGTETATGGTT---TTSTTTTTTSASTTPSATTTATATTASGATTPSATTTATTT 205
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 115-275 4.66e-05

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 43.76  E-value: 4.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    115 TGFGNfgTSTSSGGLFGTTNTTsnpfGSTSGSLFGPSSFTAAPTgttikfnpptgtdtmvkagvstnistkhqcitamke 194
Cdd:pfam13634    1 GLFGA--ATSTSGGLFGNTSTT----AASGGGLFGAASTATATT------------------------------------ 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    195 yesksleelrledyqanrkgpqnqvgagTTTGLFGSSPATSSATGLFSSSTTNSGFAygQNKTAFG-TSTTGFGTNPGGL 273
Cdd:pfam13634   39 ----------------------------SGGGLFGNSSSNAPSGGLFGATNTTTQTA--TGGGLFGnNAATTTSTTGGGL 88


                   ..
gi 56549645    274 FG 275
Cdd:pfam13634   89 FG 90
PPE COG5651
PPE-repeat protein [Function unknown];
233-476 1.04e-04

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 46.81  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  233 ATSSATGL--FSS---STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFS--KPFGQATTTQNTGFSfgnt 305
Cdd:COG5651  157 ASAAAVALtpFTQpppTITNPGGLLGAQNAGSGNTSSNPGFANLGLTGLNQVGIGGLNSgsGPIGLNSGPGNTGFA---- 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  306 stigqpSTNTMGLFGVTQASQPGGLFGTATNtstgtafgtgtgLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT 385
Cdd:COG5651  233 ------GTGAAAGAAAAAAAAAAAAGAGASA------------ALASLAATLLNASSLGLAATAASSAATNLGLAGSPLG 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  386 TSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAP 465
Cdd:COG5651  295 LAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAA 374

                        250
                 ....*....|.
gi 56549645  466 QAPVALTDPNA 476
Cdd:COG5651  375 AGAASGGGAAA 385
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
26-167 2.25e-04

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 45.90  E-value: 2.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG3469   75 TTSTTATATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVS 154

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56549645  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNpfgSTSGSLFGPSSFTAAPTGTTIKFNPP 167
Cdd:COG3469  155 GTETATGGTTTTSTTTTTTSASTTPSATTTATA---TTASGATTPSATTTATTTGPPTPGLP 213
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 243-666 3.01e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 45.68  E-value: 3.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    243 SSTTNSGFAYGQNKTaFGTSTTGFGTNPGGLFGQQNQQTTSlfskpfgqaTTTQNTGFSFGNTSTIGQPSTNTMGlfgvt 322
Cdd:pfam05109  374 SGCENISGAFASNRT-FDITVSGLGTAPKTLIITRTATNAT---------TTTHKVIFSKAPESTTTSPTLNTTG----- 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    323 qasqpgglfgtatntstgtafgtgtglFGQTNTGFGAVGSTLFGNNkLTTFGSSTTSAPSFGTTSGGLFGfgtNTSGNSI 402
Cdd:pfam05109  439 ---------------------------FAAPNTTTGLPSSTHVPTN-LTAPASTGPTVSTADVTSPTPAG---TTSGASP 487

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    403 FGSKPAPGTLGTGLGAGFGTAlgagQASLFGNNQPKIGGPlgTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQA 482
Cdd:pfam05109  488 VTPSPSPRDNGTESKAPDMTS----PTSAVTTPTPNATSP--TPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPA 561

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    483 VLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKalTTPTHYKLTPRPATRVRPKALQTTGTAKSHlfdgl 562
Cdd:pfam05109  562 VTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANT--TNHTLGGTSSTPVVTSPPKNATSAVTTGQH----- 634

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    563 dddepslangaFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASP---SEYPENGERFSFLSKPVDENHqqdgdedslvs 639
Cdd:pfam05109  635 -----------NITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPlltSAHPTGGENITQVTPASTSTH----------- 692

                          410       420
                   ....*....|....*....|....*..
gi 56549645    640 HFYTNPIAkPIPQTPESAGNKHSNSNS 666
Cdd:pfam05109  693 HVSTSSPA-PRPGTTSQASGPGNSSTS 718
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
72-337 5.34e-04

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 44.74  E-value: 5.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   72 ATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPS 151
Cdd:COG3469    3 SVSTAASPTAGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  152 SFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTkhqcitamkeyesksleelrledyqanrkgPQNQVGAGTTTGLFGSS 231
Cdd:COG3469   83 TAAAAAATSTSATLVATSTASGANTGTSTVTTT------------------------------STGAGSVTSTTSSTAGS 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  232 PATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPgglfgqqnqqttslfskpfgqaTTTQNTGFSFGNTSTIGQP 311
Cdd:COG3469  133 TTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTT----------------------TTSASTTPSATTTATATTA 190

                        250       260
                 ....*....|....*....|....*.
gi 56549645  312 StntmglfGVTQASQPGglfgTATNT 337
Cdd:COG3469  191 S-------GATTPSATT----TATTT 205
NupH_GANP pfam16768
Nucleoporin homology of Germinal-centre associated nuclear protein; NupH_GANP is the ...
 25-311 1.32e-03

Nucleoporin homology of Germinal-centre associated nuclear protein; NupH_GANP is the nucleoporin-homology domain at the N-terminus of human GANP or germinal-centre associated nuclear proteins. GANP is part of the TREX-2 complex that links transcription with nuclear messenger RNA export, and it associates with the mRNP particle through the interaction of the NupH_GANP with NXF1, the export factor. This attachment mediates efficient delivery of mRNPs to nuclear pore complexes.


Pssm-ID: 435572 [Multi-domain]  Cd Length: 292  Bit Score: 42.59  E-value: 1.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645     25 QNTGFGTTSGGAFGTsafgssnntgglfgnSQTKPGGLFGTSS-FSQPATSTSTGFGFGTSTGtantlFGTASTGTSLFS 103
Cdd:pfam16768   10 QPSAFSTSSSPSTGT---------------FQAKPPFRFGQPSlFGQNNTLSGKNSGFSQVSS-----FPTTSGVSHSSS 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    104 SQNNAFAQnkptgfgnfgtsTSSGGLFGTTNTTSnPFGSTSgslfGPSSfTAAPTGTTIKFNPPTGTdtmvkaGVSTNIS 183
Cdd:pfam16768   70 GQTLGFTQ------------TSGVGLFSGLEHTP-SFVATS----GPSS-SSVPSNPGFSFKSPTNL------GAFPSTS 125

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    184 TKHQCITAMK-------EYESKSLEELRLEDYQANRKGP---QNQVGAGTTTglFgSSPATSSATGLF--------SSST 245
Cdd:pfam16768  126 TFGPESGEVAssgfgktEFSFKPPENAVFRPIFGAESEPektQSQITSGFFT--F-SHPVSSGPGGLApfsfsqvtSSSA 202

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56549645    246 TNSGFAYGQNKTAFGTSTTGFGTNPGglfgqQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
Cdd:pfam16768  203 TSSNFTFSKPVSSNNSSSAFAPALSS-----QNVEEEKRGPKSFFGSSNSSFTSFPNSSSGSLGEP 263
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 226-407 1.71e-03

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 43.12  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    226 GLFGSSPATSSATGLFSSSTTNSGFA--YGQNKTAFGTSTTGFGtnpgglFGqqnqqttslFSKPFGQAT-------TTQ 296
Cdd:pfam15967   61 GLFGQKPATGFTFGTPASSTAATGPTglTLGTPAATTAASTGFS------LG---------FNKPAASATpfslpasSTS 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    297 NTGFSFGNTSTIGQP----STNTMGLFGVTQASQPgglfGTATNTSTGTAFGTGTGLFGQTN-TGFGAvgSTLFGNNKLT 371
Cdd:pfam15967  126 GGGLSLGSVLTSTAAqqgaTGFTLNLGGTPATTTA----VSTGLSLGSTLTSLGGSLFQNTNsTGLGQ--TTLGLTLLAT 199

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 56549645    372 TFGSSTTSAPSFGTtsGGL-FGFGTNTSGNSIFGSKP 407
Cdd:pfam15967  200 STAPVSAPAASEGL--GGLdFSTSSEKKSDKASGTRP 234
34 PHA02584
long tail fiber, proximal subunit; Provisional
 25-175 3.04e-03

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 42.43  E-value: 3.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    25 QNTGFGTTSGGAFGTSAFGSSNNTGG---------------------------LFGNSQTKPGGlfGTSSFSQPATSTST 77
Cdd:PHA02584  944 QNTSNGTVVVVDETSIAFYSQNNTTGnivfnidgtvdpinvnangtlnatgvaTNGRAVYAEGG--GIARTNNAARAITG 1021

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    78 GFGFGTSTGTANTLFGTASTGTSLFSSQ-----NNAFAQNK--PTGFGNFGTSTSSGGLfgttnTTSNPFGSTSGSlfgp 150
Cdd:PHA02584 1022 GFTIRNDGSTTVFLLTAAGDQTGGFNGLksliiNNANGQVTinDNYIINAGGTIMSGGL-----TVNSRIRSQGTK---- 1092

                         170       180
                  ....*....|....*....|....*
gi 56549645   151 SSFTAAPTGTTIKFNPPTGTDTMVK 175
Cdd:PHA02584 1093 ASYTRAPTADTVGFWSVDINDSATY 1117
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 25-152 4.33e-03

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 41.52  E-value: 4.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NSQ--------------------TKPGGLFGTSSFSQPATSTSTG 78
Cdd:cd21118  145 GGTGGPWASGGNYGTNSLGGSVGQGGNGGplnygtNSQgavaqpgygtvrgnnqnsgcTNPPPSGSHESFSNSGGSSSSG 224

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56549645   79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLFG-TTNTTSNPFGSTSGSLFGPSS 152
Cdd:cd21118  225 SSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSgNSGGSNGGSSGNSGSGSGgSSSGGSNGWGGSSSSGGSGGS 300
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
214-389 4.48e-03

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 41.66  E-value: 4.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  214 GPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQ-TTSLFSKPFGQA 292
Cdd:COG3469   29 AASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATlVATSTASGANTG 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  293 TTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
Cdd:COG3469  109 TSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTPSATTTATAT 188

                        170
                 ....*....|....*....
gi 56549645  373 --FGSSTTSAPSFGTTSGG 389
Cdd:COG3469  189 taSGATTPSATTTATTTGP 207
PTZ00473 PTZ00473
Plasmodium Vir superfamily; Provisional
 26-100 4.53e-03

Plasmodium Vir superfamily; Provisional


Pssm-ID: 240430 [Multi-domain]  Cd Length: 420  Bit Score: 41.37  E-value: 4.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645    26 NTGFGTTSGGAF--------------GTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTl 91
Cdd:PTZ00473  315 RGPYNANYGGQFnsrsgrtgssesirGFTYDSSTTYGGSSYGTSQTDSTSTYGSRSTFDSSTGGGSQSGGGSTYGGSST- 393


                  ....*....
gi 56549645    92 FGTASTGTS 100
Cdd:PTZ00473  394 FDGSSRGSS 402
PPE COG5651
PPE-repeat protein [Function unknown];
26-159 7.87e-03

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 40.65  E-value: 7.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645   26 NTGFGTTSGGAFGTSAFGSSNN-TGGLFGNSQTKPGGLFGTS---SFSQPATSTSTGFGFGTST---------GTANTLF 92
Cdd:COG5651  194 NPGFANLGLTGLNQVGIGGLNSgSGPIGLNSGPGNTGFAGTGaaaGAAAAAAAAAAAAGAGASAalaslaatlLNASSLG 273

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56549645   93 GTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTG 159
Cdd:COG5651  274 LAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAAAAAAGAA 340
PPE COG5651
PPE-repeat protein [Function unknown];
214-401 9.51e-03

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 40.26  E-value: 9.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  214 GPQNQVGAGTTTGLFGSSPAtssATGLFSSSTTNSGFAYGqnktafgTSTTGF---GTNPGGLFGQQNQQTTSLF---SK 287
Cdd:COG5651  189 GNTSSNPGFANLGLTGLNQV---GIGGLNSGSGPIGLNSG-------PGNTGFagtGAAAGAAAAAAAAAAAAGAgasAA 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56549645  288 PFGQATTTQNTGFSFGNTSTIGQPSTNTmgLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367
Cdd:COG5651  259 LASLAATLLNASSLGLAATAASSAATNL--GLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAAAAA 336

                        170       180       190
                 ....*....|....*....|....*....|....
gi 56549645  368 NKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNS 401
Cdd:COG5651  337 AGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGS 370
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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