NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1937928886|ref|NP_663715|]
View 

filamin-A-interacting protein 1 [Rattus norvegicus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CortBP2 pfam09727
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ...
 73-254 2.27e-71

Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.


:

Pssm-ID: 462860 [Multi-domain]  Cd Length: 187  Bit Score: 235.96  E-value: 2.27e-71
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   73 ELSKEDLIQLLSIMEGELQAREDVIHMLRTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYE----KPIS 148
Cdd:pfam09727    1 DLSKDDLLKLLSILEGELQARDIVIAVLKAEKVKQLLLEARYGFKYPSDPLLALQRDSELLRDQSQDEDVYEamyeKPLA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  149 ELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 228
Cdd:pfam09727   81 ELEKLVEKQRETQRRMLEQLAAAEKRHRRVIRELEEEKRKHARDTAQGDDFTYLLEKERERLKQELEQEKAQQKRLEKEL 160

                          170       180
                   ....*....|....*....|....*.
gi 1937928886  229 AKRLNKLRDELVKLKSFALMLVDERQ 254
Cdd:pfam09727  161 KKLLEKLEEELSKQKQIALLLVKERK 186
PRK03918 super family cl35229
DNA double-strand break repair ATPase Rad50;
204-745 8.23e-22

DNA double-strand break repair ATPase Rad50;


The actual alignment was detected with superfamily member PRK03918:

Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 102.45  E-value: 8.23e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  204 EQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfALMLVDERQMHIEQLGLQSQKVQ----DLTQKLREEEE 279
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEK-EVKELEELKEEIEELEKELESLEgskrKLEEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  280 KLKAVTYKSKEDRQKLLKLEvDFEHKA---SRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEE 356
Cdd:PRK03918   267 RIEELKKEIEELEEKVKELK-ELKEKAeeyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  357 ELQELREKIAKGECGNS------SLMAEVESLRKRVlemegKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR 430
Cdd:PRK03918   346 KLKELEKRLEELEERHElyeeakAKKEELERLKKRL-----TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  431 MSELEKLEEAFSRSKSEC--TQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMlv 508
Cdd:PRK03918   421 IKELKKAIEELKKAKGKCpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL-- 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  509 derKNMMEKIKQEERKVDGLN-KNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEeKVYSLTKERDELMGKLRSEEERSCE 587
Cdd:PRK03918   499 ---KELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAE 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  588 LScsVDLLKKRLDGIEEVEREINRGRsckgseftcPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFR 667
Cdd:PRK03918   575 LL--KELEELGFESVEELEERLKELE---------PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  668 TEQDKANFLSQQLEEIKHQMAKHKAIEKGEAVSQ-EAEL-RHRFRLEEAKS--RDLQAEVQALKEKIHELMNKEDQLSQL 743
Cdd:PRK03918   644 ELRKELEELEKKYSEEEYEELREEYLELSRELAGlRAELeELEKRREEIKKtlEKLKEELEEREKAKKELEKLEKALERV 723


                   ..
gi 1937928886  744 QV 745
Cdd:PRK03918   724 EE 725
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 913-1177 3.06e-07

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 54.92  E-value: 3.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  913 VTP-----DHENSTATLEITSPTSeeffSSTTVIPTLGNQKPRITIiPSPNVMSqkpksadPTLGPERAMSPVTiTTISR 987
Cdd:pfam05109  488 VTPspsprDNGTESKAPDMTSPTS----AVTTPTPNATSPTPAVTT-PTPNATS-------PTLGKTSPTSAVT-TPTPN 554

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  988 EKSPEGGRSAFADRPASPIQIMTVSTSA--APTEIAVSPESQEV-PMGRTILKVTPEKQTVPAPVRKYNSNANIITTEDN 1064
Cdd:pfam05109  555 ATSPTPAVTTPTPNATIPTLGKTSPTSAvtTPTPNATSPTVGETsPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQH 634

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1065 KIHIHLGSQFKRSPGPAAEGVSPVITvrpVNVTAEKEVSTGTVLRSPRNHLSSRPGASKVTSTITITPVTTSSTRGTQSV 1144
Cdd:pfam05109  635 NITSSSTSSMSLRPSSISETLSPSTS---DNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG 711

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1937928886 1145 SGQDGSSQRP--------TPTRIPMS----KGMKAGKPVVAASGA 1177
Cdd:pfam05109  712 PGNSSTSTKPgevnvtkgTPPKNATSpqapSGQKTAVPTVTSTGG 756
 
Name Accession Description Interval E-value
CortBP2 pfam09727
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ...
 73-254 2.27e-71

Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.


Pssm-ID: 462860 [Multi-domain]  Cd Length: 187  Bit Score: 235.96  E-value: 2.27e-71
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   73 ELSKEDLIQLLSIMEGELQAREDVIHMLRTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYE----KPIS 148
Cdd:pfam09727    1 DLSKDDLLKLLSILEGELQARDIVIAVLKAEKVKQLLLEARYGFKYPSDPLLALQRDSELLRDQSQDEDVYEamyeKPLA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  149 ELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 228
Cdd:pfam09727   81 ELEKLVEKQRETQRRMLEQLAAAEKRHRRVIRELEEEKRKHARDTAQGDDFTYLLEKERERLKQELEQEKAQQKRLEKEL 160

                          170       180
                   ....*....|....*....|....*.
gi 1937928886  229 AKRLNKLRDELVKLKSFALMLVDERQ 254
Cdd:pfam09727  161 KKLLEKLEEELSKQKQIALLLVKERK 186
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
204-745 8.23e-22

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 102.45  E-value: 8.23e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  204 EQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfALMLVDERQMHIEQLGLQSQKVQ----DLTQKLREEEE 279
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEK-EVKELEELKEEIEELEKELESLEgskrKLEEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  280 KLKAVTYKSKEDRQKLLKLEvDFEHKA---SRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEE 356
Cdd:PRK03918   267 RIEELKKEIEELEEKVKELK-ELKEKAeeyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  357 ELQELREKIAKGECGNS------SLMAEVESLRKRVlemegKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR 430
Cdd:PRK03918   346 KLKELEKRLEELEERHElyeeakAKKEELERLKKRL-----TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  431 MSELEKLEEAFSRSKSEC--TQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMlv 508
Cdd:PRK03918   421 IKELKKAIEELKKAKGKCpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL-- 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  509 derKNMMEKIKQEERKVDGLN-KNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEeKVYSLTKERDELMGKLRSEEERSCE 587
Cdd:PRK03918   499 ---KELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAE 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  588 LScsVDLLKKRLDGIEEVEREINRGRsckgseftcPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFR 667
Cdd:PRK03918   575 LL--KELEELGFESVEELEERLKELE---------PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  668 TEQDKANFLSQQLEEIKHQMAKHKAIEKGEAVSQ-EAEL-RHRFRLEEAKS--RDLQAEVQALKEKIHELMNKEDQLSQL 743
Cdd:PRK03918   644 ELRKELEELEKKYSEEEYEELREEYLELSRELAGlRAELeELEKRREEIKKtlEKLKEELEEREKAKKELEKLEKALERV 723


                   ..
gi 1937928886  744 QV 745
Cdd:PRK03918   724 EE 725
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 120-733 1.39e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 1.39e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  120 EKVLRVLHRDAILAQEKSIGEdvyekpisELDRLEEKQKETyrrmLEQLLLAEKchrrtvyELENEKHKHTDymnKSDDF 199
Cdd:COG1196    226 EAELLLLKLRELEAELEELEA--------ELEELEAELEEL----EAELAELEA-------ELEELRLELEE---LELEL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  200 TNLLEQERERLKKL--LEQEKAYQARKEKENAKRLNKLRDELVKLKsfalmlvDERQMHIEQLGLQSQKVQDLTQKLREE 277
Cdd:COG1196    284 EEAQAEEYELLAELarLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEELEEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  278 EEKLKAVtyksKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEE 357
Cdd:COG1196    357 EAELAEA----EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  358 LQELREkiakgecgnsslmAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKL 437
Cdd:COG1196    433 LEEEEE-------------EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  438 EEAFSrSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD-DLTKLKSFTVMLVDERKNMME 516
Cdd:COG1196    500 EADYE-GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDeVAAAAIEYLKAAKAGRATFLP 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  517 KIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYsltKERDELMGKLRSEEERscelscsVDLLK 596
Cdd:COG1196    579 LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL---VAARLEAALRRAVTLA-------GRLRE 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  597 KRLDGIEEVEREINRGRSCKGseftcpEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFL 676
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRE------LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  677 SQQLEEIKHQMAKHKAIEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHEL 733
Cdd:COG1196    723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 152-776 3.91e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 3.91e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  152 RLEEKQKETYRRM------LEQL--LLAEKchRRTVYELENEKHKHTDYMNKSDDFTNL--------LEQERERLKKLLE 215
Cdd:TIGR02168  169 KYKERRKETERKLertrenLDRLedILNEL--ERQLKSLERQAEKAERYKELKAELRELelallvlrLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  216 QEKAYQaRKEKENAKRLNKLRDELVKLKSFalMLVDERQMHIEQLGLQS--QKVQDLTQKLREEEEKL-------KAVTY 286
Cdd:TIGR02168  247 ELKEAE-EELEELTAELQELEEKLEELRLE--VSELEEEIEELQKELYAlaNEISRLEQQKQILRERLanlerqlEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  287 KSKEDRQKLLKLEVDFEHKASRFSQ----------EHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKaee 356
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEElkeelesleaELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN--- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  357 ELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKD--EEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL 434
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  435 EKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNE---LEVVKSRVKELECSESRLEKA-ELSLKDDLTklksftvMLVDE 510
Cdd:TIGR02168  481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNqsgLSGILGVLSELISVDEGYEAAiEAALGGRLQ-------AVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  511 RKNMMEKI----KQEE--------------RKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYsLTKERD 572
Cdd:TIGR02168  554 NLNAAKKAiaflKQNElgrvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL-VVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  573 ELMGKLRSEEERSCELSCSVDLLK----------KRLDGIEEVEREINRGRSC-KGSEftcpedNKIRELTLEIERLKKR 641
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDGDLVRpggvitggsaKTNSSILERRREIEELEEKiEELE------EKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  642 LQQLEVVEGDLMKTEDEYDQ----LEQKFRTEQDKANFLSQQLEEIKHQMAKHKAIEKGEAvSQEAELRHRFRLEEAKSR 717
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRqisaLRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE-ERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1937928886  718 DLQAEVQALKEKI----HELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE 776
Cdd:TIGR02168  786 ELEAQIEQLKEELkalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 151-798 8.26e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.15  E-value: 8.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  151 DRLEEKQKETYRRMleQLLLAEKCHR--RTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 228
Cdd:pfam15921  245 DQLEALKSESQNKI--ELLLQQHQDRieQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  229 AKRLNKLRDELVKLKSfalMLVDErqmhIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLkleVDFEHKASR 308
Cdd:pfam15921  323 ESTVSQLRSELREAKR---MYEDK----IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLL---ADLHKREKE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  309 FSQEHEEmNAKLANQESHNR----QLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGN----SSLMAEVE 380
Cdd:pfam15921  393 LSLEKEQ-NKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESlekvSSLTAQLE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  381 S----LRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR----MSELEKL---EEAFSRSKSECT 449
Cdd:pfam15921  472 StkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdlkLQELQHLkneGDHLRNVQTECE 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  450 QLHLNLEKEKNLTKDLLNELEVVKSRVKE--LECSESRLEKAEL--SLKDDLTKLKSFTVMlvDERKNmmEKIKQEERKV 525
Cdd:pfam15921  552 ALKLQMAEKDKVIEILRQQIENMTQLVGQhgRTAGAMQVEKAQLekEINDRRLELQEFKIL--KDKKD--AKIRELEARV 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  526 DGLNKnfkveqgkvmdvteklieESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRL-DGIEE 604
Cdd:pfam15921  628 SDLEL------------------EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFrNKSEE 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  605 VEREINRGRSckgseftcpednKIRELTLEIERLKKRLQQLEVVEGDLMKT----EDEYDQLEQKFRTEQDKANFLSQQL 680
Cdd:pfam15921  690 METTTNKLKM------------QLKSAQSELEQTRNTLKSMEGSDGHAMKVamgmQKQITAKRGQIDALQSKIQFLEEAM 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  681 EEIKHQmaKHKAIEKGEAVSQEAELRHRFRLEEAKSRD-LQAEVQALKEKIhelMNKEDQLSQLQVDYSVLQQRFMEEET 759
Cdd:pfam15921  758 TNANKE--KHFLKEEKNKLSQELSTVATEKNKMAGELEvLRSQERRLKEKV---ANMEVALDKASLQFAECQDIIQRQEQ 832

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1937928886  760 KNKNMGREVLNLTKELE------LSKRYSRALRPSGNGRRMVDVP 798
Cdd:pfam15921  833 ESVRLKLQHTLDVKELQgpgytsNSSMKPRLLQPASFTRTHSNVP 877
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 913-1177 3.06e-07

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 54.92  E-value: 3.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  913 VTP-----DHENSTATLEITSPTSeeffSSTTVIPTLGNQKPRITIiPSPNVMSqkpksadPTLGPERAMSPVTiTTISR 987
Cdd:pfam05109  488 VTPspsprDNGTESKAPDMTSPTS----AVTTPTPNATSPTPAVTT-PTPNATS-------PTLGKTSPTSAVT-TPTPN 554

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  988 EKSPEGGRSAFADRPASPIQIMTVSTSA--APTEIAVSPESQEV-PMGRTILKVTPEKQTVPAPVRKYNSNANIITTEDN 1064
Cdd:pfam05109  555 ATSPTPAVTTPTPNATIPTLGKTSPTSAvtTPTPNATSPTVGETsPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQH 634

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1065 KIHIHLGSQFKRSPGPAAEGVSPVITvrpVNVTAEKEVSTGTVLRSPRNHLSSRPGASKVTSTITITPVTTSSTRGTQSV 1144
Cdd:pfam05109  635 NITSSSTSSMSLRPSSISETLSPSTS---DNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG 711

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1937928886 1145 SGQDGSSQRP--------TPTRIPMS----KGMKAGKPVVAASGA 1177
Cdd:pfam05109  712 PGNSSTSTKPgevnvtkgTPPKNATSpqapSGQKTAVPTVTSTGG 756
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 148-350 1.62e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  148 SELDRLEEKQKETyRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKE 227
Cdd:COG4942     27 AELEQLQQEIAEL-EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  228 NAKRLNKL---------------RDELVKLKSFALM--LVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKE 290
Cdd:COG4942    106 LAELLRALyrlgrqpplalllspEDFLDAVRRLQYLkyLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  291 DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKS 350
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 954-1166 6.97e-04

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 43.76  E-value: 6.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  954 IPSPNVMSQKPKSAD-------------PTLGPERAMSPVTITTISREKSPeggRSAFAD--RPASPIQIMTVSTSAAPT 1018
Cdd:PLN03209   323 IPSQRVPPKESDAADgpkpvptkpvtpeAPSPPIEEEPPQPKAVVPRPLSP---YTAYEDlkPPTSPIPTPPSSSPASSK 399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1019 E---IAVSPESQEVPMGRTILKVtPEKQTVPAPVRKYNSNANIITTEDNKIhihlgsqfKRSPGPAAE-GVSPVITVRPV 1094
Cdd:PLN03209   400 SvdaVAKPAEPDVVPSPGSASNV-PEVEPAQVEAKKTRPLSPYARYEDLKP--------PTSPSPTAPtGVSPSVSSTSS 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1095 nVTAEKEVSTGTV-----------------------LRSPRNHLSSRPGASKVTSTITITPVTTSSTRGTQSVSGQDGSS 1151
Cdd:PLN03209   471 -VPAVPDTAPATAatdaaapppanmrplspyavyddLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQ 549

                          250
                   ....*....|....*.
gi 1937928886 1152 QRPTP-TRIPMSKGMK 1166
Cdd:PLN03209   550 PKPRPlSPYTMYEDLK 565
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 336-504 1.21e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.31  E-value: 1.21e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   336 GLSQRIEELEETNKSLQKAEEELQELREKIAKGecgNSSLMAEVESLRKRVLEMEGKDEEITKteaqcrELKKKLQEEEH 415
Cdd:smart00787  148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDR---KDALEEELRQLKQLEDELEDCDPTELD------RAKEKLKKLLQ 218

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   416 HSKELRLEVEKLQKRMSELEKleeafsrsksectqlhlNLEKEKNLTKDLLNELEVVKSRVKELE-CSESRLEKaelsLK 494
Cdd:smart00787  219 EIMIKVKKLEELEEELQELES-----------------KIEDLTNKKSELNTEIAEAEKKLEQCRgFTFKEIEK----LK 277

                           170
                    ....*....|
gi 1937928886   495 DDLTKLKSFT 504
Cdd:smart00787  278 EQLKLLQSLT 287
mukB PRK04863
chromosome partition protein MukB;
72-413 1.83e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   72 VELSKE--DLIQLLSIMEGELQA--------REDVIHMLRTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEK-SIGE 140
Cdd:PRK04863   310 VEMARElaELNEAESDLEQDYQAasdhlnlvQTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARaEAAE 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  141 DVYEKPISEL----DRLEEKQKET--YRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERL---K 211
Cdd:PRK04863   390 EEVDELKSQLadyqQALDVQQTRAiqYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLsvaQ 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  212 KLLEQ-EKAYQA-RK-----EKENAKrlNKLRDELVKLKSFalmlvderQMHIEQLGLQSQKVQDLTQKLREEEEKLKAV 284
Cdd:PRK04863   470 AAHSQfEQAYQLvRKiagevSRSEAW--DVARELLRRLREQ--------RHLAEQLQQLRMRLSELEQRLRQQQRAERLL 539

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  285 TYKSKEDRQKLLKlEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREK 364
Cdd:PRK04863   540 AEFCKRLGKNLDD-EDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQ 618

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1937928886  365 IakGECGNSSlmAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEE 413
Cdd:PRK04863   619 S--GEEFEDS--QDVTEYMQQLLERE---RELTVERDELAARKQALDEE 660
 
Name Accession Description Interval E-value
CortBP2 pfam09727
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ...
 73-254 2.27e-71

Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.


Pssm-ID: 462860 [Multi-domain]  Cd Length: 187  Bit Score: 235.96  E-value: 2.27e-71
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   73 ELSKEDLIQLLSIMEGELQAREDVIHMLRTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYE----KPIS 148
Cdd:pfam09727    1 DLSKDDLLKLLSILEGELQARDIVIAVLKAEKVKQLLLEARYGFKYPSDPLLALQRDSELLRDQSQDEDVYEamyeKPLA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  149 ELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 228
Cdd:pfam09727   81 ELEKLVEKQRETQRRMLEQLAAAEKRHRRVIRELEEEKRKHARDTAQGDDFTYLLEKERERLKQELEQEKAQQKRLEKEL 160

                          170       180
                   ....*....|....*....|....*.
gi 1937928886  229 AKRLNKLRDELVKLKSFALMLVDERQ 254
Cdd:pfam09727  161 KKLLEKLEEELSKQKQIALLLVKERK 186
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
204-745 8.23e-22

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 102.45  E-value: 8.23e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  204 EQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfALMLVDERQMHIEQLGLQSQKVQ----DLTQKLREEEE 279
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEK-EVKELEELKEEIEELEKELESLEgskrKLEEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  280 KLKAVTYKSKEDRQKLLKLEvDFEHKA---SRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEE 356
Cdd:PRK03918   267 RIEELKKEIEELEEKVKELK-ELKEKAeeyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  357 ELQELREKIAKGECGNS------SLMAEVESLRKRVlemegKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR 430
Cdd:PRK03918   346 KLKELEKRLEELEERHElyeeakAKKEELERLKKRL-----TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  431 MSELEKLEEAFSRSKSEC--TQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMlv 508
Cdd:PRK03918   421 IKELKKAIEELKKAKGKCpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL-- 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  509 derKNMMEKIKQEERKVDGLN-KNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEeKVYSLTKERDELMGKLRSEEERSCE 587
Cdd:PRK03918   499 ---KELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAE 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  588 LScsVDLLKKRLDGIEEVEREINRGRsckgseftcPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFR 667
Cdd:PRK03918   575 LL--KELEELGFESVEELEERLKELE---------PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  668 TEQDKANFLSQQLEEIKHQMAKHKAIEKGEAVSQ-EAEL-RHRFRLEEAKS--RDLQAEVQALKEKIHELMNKEDQLSQL 743
Cdd:PRK03918   644 ELRKELEELEKKYSEEEYEELREEYLELSRELAGlRAELeELEKRREEIKKtlEKLKEELEEREKAKKELEKLEKALERV 723


                   ..
gi 1937928886  744 QV 745
Cdd:PRK03918   724 EE 725
PTZ00121 PTZ00121
MAEBL; Provisional
 144-778 1.08e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 89.43  E-value: 1.08e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  144 EKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR 223
Cdd:PTZ00121  1211 ERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKK 1290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  224 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQlglQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFE 303
Cdd:PTZ00121  1291 KADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE---AKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  304 HKASRFSQEHEEMNA--KLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVES 381
Cdd:PTZ00121  1368 AAEKKKEEAKKKADAakKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAD 1447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  382 LRKRVLEMEGKDEEITKTEAQCR---ELKKKlQEEEHHSKELRLEVEKLQKRMSELEKLEEAfsrsKSECTQLHLNLEKE 458
Cdd:PTZ00121  1448 EAKKKAEEAKKAEEAKKKAEEAKkadEAKKK-AEEAKKADEAKKKAEEAKKKADEAKKAAEA----KKKADEAKKAEEAK 1522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  459 KnltKDLLNELEvVKSRVKELECSESRLEKAELSLKDDLTKlksftvmlVDERKNMMEKIKQEERKVDGLNKNFKVEQgk 538
Cdd:PTZ00121  1523 K---ADEAKKAE-EAKKADEAKKAEEKKKADELKKAEELKK--------AEEKKKAEEAKKAEEDKNMALRKAEEAKK-- 1588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  539 vmdVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEV--EREINRGRSCK 616
Cdd:PTZ00121  1589 ---AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELkkAEEENKIKAAE 1665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  617 GSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEdeydQLEQKFRTEQDKANFLSQQLEE--IKHQMAKHKAIE 694
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE----ELKKKEAEEKKKAEELKKAEEEnkIKAEEAKKEAEE 1741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  695 ---KGEAVSQEAE----LRHRFRLEEAKSRDLQAEVQALkekIHELMNKEDQLSQLQVDYSVLQQRFMEEE-TKNKNMGR 766
Cdd:PTZ00121  1742 dkkKAEEAKKDEEekkkIAHLKKEEEKKAEEIRKEKEAV---IEEELDEEDEKRRMEVDKKIKDIFDNFANiIEGGKEGN 1818

                          650
                   ....*....|..
gi 1937928886  767 EVLNLTKELELS 778
Cdd:PTZ00121  1819 LVINDSKEMEDS 1830
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
265-784 7.09e-16

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 83.19  E-value: 7.09e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  265 QKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQ------EHEEMNAKLANQESHNRQLRLKLVGLS 338
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEleelkeEIEELEKELESLEGSKRKLEEKIRELE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  339 QRIEELEETNKSLQKAEEELQELREKIAKGEcgnsSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHS- 417
Cdd:PRK03918   266 ERIEELKKEIEELEEKVKELKELKEKAEEYI----KLSEFYEEYLDELREIE---KRLSRLEEEINGIEERIKELEEKEe 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  418 --KELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKdllnelEVVKSRVKELECSESRLEKAELSLKD 495
Cdd:PRK03918   339 rlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP------EKLEKELEELEKAKEEIEEEISKITA 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  496 DLTKLKSftvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKvmDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELM 575
Cdd:PRK03918   413 RIGELKK----EIKELKKAIEELKKAKGKCPVCGRELTEEHRK--ELLEEYTAELKRIEKELKEIEEKERKLRKELRELE 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  576 GKLRSEEERSCELSCSVDL--LKKRLDGI--EEVEREINRGRSCKGseftcpednKIRELTLEIERLKKRLQQLEVVEGD 651
Cdd:PRK03918   487 KVLKKESELIKLKELAEQLkeLEEKLKKYnlEELEKKAEEYEKLKE---------KLIKLKGEIKSLKKELEKLEELKKK 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  652 LMKTEDEYDQLEQKfrteqdkanflsqqLEEIKHQMAK--HKAIEKGEAVSQEAELRHRFRLE--------EAKSRDLQA 721
Cdd:PRK03918   558 LAELEKKLDELEEE--------------LAELLKELEElgFESVEELEERLKELEPFYNEYLElkdaekelEREEKELKK 623

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1937928886  722 EVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNmgrevlnlTKELELSKRYSRA 784
Cdd:PRK03918   624 LEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELR--------EEYLELSRELAGL 678
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
287-776 1.26e-15

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 82.42  E-value: 1.26e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  287 KSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEET--------------NKSLQ 352
Cdd:PRK03918   176 RRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeeieelekeleslEGSKR 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  353 KAEEELQELREKIAKGEcgnsSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMS 432
Cdd:PRK03918   256 KLEEKIRELEERIEELK----KEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  433 ELEKLEEAFSRSKSECTQLHLNLE------KEKNLTKDLLNELEVVKSRVKELECSE-----SRLEKAELSLKDDLTKLK 501
Cdd:PRK03918   332 ELEEKEERLEELKKKLKELEKRLEeleerhELYEEAKAKKEELERLKKRLTGLTPEKlekelEELEKAKEEIEEEISKIT 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  502 SFTVML---VDERKNMMEKIKQEERKVDGLNKNFKVEQGKvmDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKL 578
Cdd:PRK03918   412 ARIGELkkeIKELKKAIEELKKAKGKCPVCGRELTEEHRK--ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVL 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  579 RSEEERSCELSCSVDL--LKKRLDGI--EEVEREINRGRSCKGseftcpednKIRELTLEIERLKKRLQQLEVVEGDLMK 654
Cdd:PRK03918   490 KKESELIKLKELAEQLkeLEEKLKKYnlEELEKKAEEYEKLKE---------KLIKLKGEIKSLKKELEKLEELKKKLAE 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  655 TEDEYDQLEQKFRTEQDK-ANFLSQQLEEIKHQMAKHKAIEKG--EAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIH 731
Cdd:PRK03918   561 LEKKLDELEEELAELLKElEELGFESVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLEEELDKAFEELAETEK 640

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1937928886  732 ELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNmgREVLNLTKELE 776
Cdd:PRK03918   641 RLEELRKELEELEKKYSEEEYEELREEYLELS--RELAGLRAELE 683
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 120-733 1.39e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 1.39e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  120 EKVLRVLHRDAILAQEKSIGEdvyekpisELDRLEEKQKETyrrmLEQLLLAEKchrrtvyELENEKHKHTDymnKSDDF 199
Cdd:COG1196    226 EAELLLLKLRELEAELEELEA--------ELEELEAELEEL----EAELAELEA-------ELEELRLELEE---LELEL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  200 TNLLEQERERLKKL--LEQEKAYQARKEKENAKRLNKLRDELVKLKsfalmlvDERQMHIEQLGLQSQKVQDLTQKLREE 277
Cdd:COG1196    284 EEAQAEEYELLAELarLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEELEEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  278 EEKLKAVtyksKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEE 357
Cdd:COG1196    357 EAELAEA----EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  358 LQELREkiakgecgnsslmAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKL 437
Cdd:COG1196    433 LEEEEE-------------EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  438 EEAFSrSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD-DLTKLKSFTVMLVDERKNMME 516
Cdd:COG1196    500 EADYE-GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDeVAAAAIEYLKAAKAGRATFLP 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  517 KIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYsltKERDELMGKLRSEEERscelscsVDLLK 596
Cdd:COG1196    579 LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL---VAARLEAALRRAVTLA-------GRLRE 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  597 KRLDGIEEVEREINRGRSCKGseftcpEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFL 676
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRE------LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  677 SQQLEEIKHQMAKHKAIEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHEL 733
Cdd:COG1196    723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 196-833 2.56e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 81.73  E-value: 2.56e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  196 SDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRD-ELVKLKSFALMLVDERQMHIEQLGLQSQKVQDL--TQ 272
Cdd:PTZ00121  1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKaEDARKAEEARKAEDAKRVEIARKAEDARKAEEArkAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  273 KLREEEEKLKAVTYKSKEDRQKllKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRlklvglsqRIEELEETNKSLQ 352
Cdd:PTZ00121  1174 DAKKAEAARKAEEVRKAEELRK--AEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK--------KAEEAKKDAEEAK 1243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  353 KAEEE--LQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEA--------QCRELKKKlQEEEHHSKELRL 422
Cdd:PTZ00121  1244 KAEEErnNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEakkaeekkKADEAKKK-AEEAKKADEAKK 1322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  423 EVEKLQKRMSELEKLEEAFSR----SKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA-ELSLKDDL 497
Cdd:PTZ00121  1323 KAEEAKKKADAAKKKAEEAKKaaeaAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdEAKKKAEE 1402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  498 TKLKSFTVMLVDERKNMMEKIK---QEERKVDGLNKnfKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKvysltKERDEL 574
Cdd:PTZ00121  1403 DKKKADELKKAAAAKKKADEAKkkaEEKKKADEAKK--KAEEAKKADEAKKKAEEAKKAEEAKKKAEEA-----KKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  575 mgKLRSEEERSC-ELSCSVDLLKKRLDGIEEVEREINRGRSC-KGSEFTCPEDNKIRELTLEIERLKK---RLQQLEVVE 649
Cdd:PTZ00121  1476 --KKKAEEAKKAdEAKKKAEEAKKKADEAKKAAEAKKKADEAkKAEEAKKADEAKKAEEAKKADEAKKaeeKKKADELKK 1553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  650 GDLMKTEDEYDQLEQKFRTEQDKANFL-----SQQLEE--IKHQMAKHKAIEKGEAVSQEAELRHRFRLEEA-KSRDLQA 721
Cdd:PTZ00121  1554 AEELKKAEEKKKAEEAKKAEEDKNMALrkaeeAKKAEEarIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkKAEEEKK 1633

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  722 EVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREvlnLTKELELSKRYSRALRPSGNGRRMVdvpvas 801
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE---AKKAEEDEKKAAEALKKEAEEAKKA------ 1704

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1937928886  802 tgvqtEAVCGDAAEEETPAVFIRKSfQEENHI 833
Cdd:PTZ00121  1705 -----EELKKKEAEEKKKAEELKKA-EEENKI 1730
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
140-654 3.52e-15

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 80.88  E-value: 3.52e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  140 EDVYEKPISELDRLEEKQK--ETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQE 217
Cdd:PRK03918   213 SSELPELREELEKLEKEVKelEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  218 KAYQARKE--KENAKRLNKLRDELVKLKSfalmLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKL 295
Cdd:PRK03918   293 EEYIKLSEfyEEYLDELREIEKRLSRLEE----EINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  296 LKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQElrekiAKGECGN--- 372
Cdd:PRK03918   369 AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK-----AKGKCPVcgr 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  373 -----------SSLMAEVESLRKRVLEMEGKDEEITKTEaqcRELKKKLQEEEHHSKELRL--EVEKLQKRMSE--LEKL 437
Cdd:PRK03918   444 elteehrkellEEYTAELKRIEKELKEIEEKERKLRKEL---RELEKVLKKESELIKLKELaeQLKELEEKLKKynLEEL 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  438 EEAfSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEK 517
Cdd:PRK03918   521 EKK-AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEP 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  518 IKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEkvysLTKERDELMGKLRSEE-----ERSCELSCSV 592
Cdd:PRK03918   600 FYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE----LRKELEELEKKYSEEEyeelrEEYLELSREL 675

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1937928886  593 DLLKKRLDGIEEVEREINrgrscKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMK 654
Cdd:PRK03918   676 AGLRAELEELEKRREEIK-----KTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKK 732
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 152-776 3.91e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 3.91e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  152 RLEEKQKETYRRM------LEQL--LLAEKchRRTVYELENEKHKHTDYMNKSDDFTNL--------LEQERERLKKLLE 215
Cdd:TIGR02168  169 KYKERRKETERKLertrenLDRLedILNEL--ERQLKSLERQAEKAERYKELKAELRELelallvlrLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  216 QEKAYQaRKEKENAKRLNKLRDELVKLKSFalMLVDERQMHIEQLGLQS--QKVQDLTQKLREEEEKL-------KAVTY 286
Cdd:TIGR02168  247 ELKEAE-EELEELTAELQELEEKLEELRLE--VSELEEEIEELQKELYAlaNEISRLEQQKQILRERLanlerqlEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  287 KSKEDRQKLLKLEVDFEHKASRFSQ----------EHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKaee 356
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEElkeelesleaELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN--- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  357 ELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKD--EEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL 434
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  435 EKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNE---LEVVKSRVKELECSESRLEKA-ELSLKDDLTklksftvMLVDE 510
Cdd:TIGR02168  481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNqsgLSGILGVLSELISVDEGYEAAiEAALGGRLQ-------AVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  511 RKNMMEKI----KQEE--------------RKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYsLTKERD 572
Cdd:TIGR02168  554 NLNAAKKAiaflKQNElgrvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL-VVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  573 ELMGKLRSEEERSCELSCSVDLLK----------KRLDGIEEVEREINRGRSC-KGSEftcpedNKIRELTLEIERLKKR 641
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDGDLVRpggvitggsaKTNSSILERRREIEELEEKiEELE------EKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  642 LQQLEVVEGDLMKTEDEYDQ----LEQKFRTEQDKANFLSQQLEEIKHQMAKHKAIEKGEAvSQEAELRHRFRLEEAKSR 717
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRqisaLRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE-ERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1937928886  718 DLQAEVQALKEKI----HELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE 776
Cdd:TIGR02168  786 ELEAQIEQLKEELkalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 203-776 1.61e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 1.61e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  203 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 282
Cdd:COG1196    205 LERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  283 AVTYKSKEDRQKLLKLEVDFEH---KASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRI----EELEETNKSLQKAE 355
Cdd:COG1196    285 EAQAEEYELLAELARLEQDIARleeRRRELEERLEELEEELAELEEELEELEEELEELEEELeeaeEELEEAEAELAEAE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  356 EELQELREKIAKGEcgnsslmAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELE 435
Cdd:COG1196    365 EALLEAEAELAEAE-------EELEELAEELLEAL---RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  436 KLEEAfsrsksectqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMM 515
Cdd:COG1196    435 EEEEE----------EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  516 EKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIE-----------------------ESKKLLKLKSEMEEKVYSLTKERD 572
Cdd:COG1196    505 GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEaaleaalaaalqnivveddevaaAAIEYLKAAKAGRATFLPLDKIRA 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  573 ELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRsckgSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDL 652
Cdd:COG1196    585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR----TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  653 MKTEDEYDQLEQKFRTEQdkanflsQQLEEIKHQMAKHKAIEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHE 732
Cdd:COG1196    661 SLTGGSRRELLAALLEAE-------AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1937928886  733 LMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE 776
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 63-757 5.06e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 5.06e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   63 ESEKKTKKSVELSKEDLIQLLSIMEGELQAREDVIHMLRTE----KTKPEVLEAHYGSAEpEKVLRVLHRDAILAQEKSI 138
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEvselEEEIEELQKELYALA-NEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  139 GEDVYEKPISELDRLEEK---QKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLE 215
Cdd:TIGR02168  314 LERQLEELEAQLEELESKldeLAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  216 QEKAYQARKEkENAKRLNKLRDELVKLKSFALMLVD-----ERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKE 290
Cdd:TIGR02168  394 QIASLNNEIE-RLEARLERLEDRRERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  291 DRQKLLKLEVDFEHKASRFS-----QEHEEMNAKLANQESHNRQlrlKLVGLSQRIEELEETNKSLQKAEEELqeLREKI 365
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDslerlQENLEGFSEGVKALLKNQS---GLSGILGVLSELISVDEGYEAAIEAA--LGGRL 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  366 AKGEC-GNSSLMAEVESLRK----RVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL------ 434
Cdd:TIGR02168  548 QAVVVeNLNAAKKAIAFLKQnelgRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlv 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  435 -EKLEEAFSRSKSecTQLHLNL------------------EKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 495
Cdd:TIGR02168  628 vDDLDNALELAKK--LRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  496 DLTKLKSFTVMLVDErknmmekIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELM 575
Cdd:TIGR02168  706 ELEELEEELEQLRKE-------LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  576 ---GKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPEdNKIRELTLEIERLKkrlQQLEVVEGDL 652
Cdd:TIGR02168  779 eaeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE-RRIAATERRLEDLE---EQIEELSEDI 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  653 MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKaiekgeavSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHE 732
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESELEALLNERASLEEALALLR--------SELEELSEELRELESKRSELRRELEELREKLAQ 926

                          730       740
                   ....*....|....*....|....*
gi 1937928886  733 LmnkEDQLSQLQVDYSVLQQRFMEE 757
Cdd:TIGR02168  927 L---ELRLEGLEVRIDNLQERLSEE 948
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 250-602 5.49e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.03  E-value: 5.49e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  250 VDERQMHIEQLGLQSQKVQdltqKLREEEEKLKAVTYKSKEDRQKLLKLEVDfEHKASRfsqehEEMNAKLANQESHNRQ 329
Cdd:TIGR02169  186 IERLDLIIDEKRQQLERLR----REREKAERYQALLKEKREYEGYELLKEKE-ALERQK-----EAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  330 LRLKLVGLSQRIEELEETNKSLQK-----AEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGK----DEEITKTE 400
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERlaklEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  401 AQCRELKKKLQEEEHHSKELRLEVEKLQKRM----SELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRV 476
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAELKEELedlrAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  477 KELECSESRLEKAELSLKDDLTKLKSftvmlvdERKNMMEKIKQEErkvdglnknfkveqGKVMDVTEKLIEESKKLLKL 556
Cdd:TIGR02169  416 QRLSEELADLNAAIAGIEAKINELEE-------EKEDKALEIKKQE--------------WKLEQLAADLSKYEQELYDL 474

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1937928886  557 KSE---MEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGI 602
Cdd:TIGR02169  475 KEEydrVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV 523
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 181-694 1.45e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 75.44  E-value: 1.45e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  181 ELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQaRKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQL 260
Cdd:TIGR04523  170 ELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKI-QKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  261 GLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDF---EHKASRFSQEHE-----EMNAKLANQESHNRQLRL 332
Cdd:TIGR04523  249 SNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLnqlKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  333 KLVGLSQRIEELEETNKSLQK----AEEELQELREKIAKGEcgnsslmAEVESLRKrvlEMEGKDEEITKTEAQCRELKK 408
Cdd:TIGR04523  329 QISQNNKIISQLNEQISQLKKeltnSESENSEKQRELEEKQ-------NEIEKLKK---ENQSYKQEIKNLESQINDLES 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  409 KLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKE-LECSESRLE 487
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETqLKVLSRSIN 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  488 KAELSLKDDLTKLKSFTvmlvDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSL 567
Cdd:TIGR04523  479 KIKQNLEQKQKELKSKE----KELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  568 TKErdELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREinrgrsckgseftcpEDNKIRELTLEIERLKKRLQQLev 647
Cdd:TIGR04523  555 KKE--NLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ---------------KEKEKKDLIKEIEEKEKKISSL-- 615

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1937928886  648 vEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKAIE 694
Cdd:TIGR04523  616 -EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKW 661
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 203-574 1.84e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 1.84e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  203 LEQERERLKKLLEQEKAYQARKEkenakRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQdltQKLREEEEKLK 282
Cdd:TIGR02169  676 LQRLRERLEGLKRELSSLQSELR-----RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK---ERLEELEEDLS 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  283 AVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNA--------KLANQESHNRQLRLKLVGLSQRIEELE-ETNKSLQK 353
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAELSKLEEEVSRIEARLREIEqKLNRLTLE 827

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  354 ---AEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLqeeehhsKELRLEVEKLQKR 430
Cdd:TIGR02169  828 keyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE---EELEELEAALRDLESRL-------GDLKKERDELEAQ 897

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  431 MSELEKLEEafsrsksectQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE---KAELSLKDdltklksftvmL 507
Cdd:TIGR02169  898 LRELERKIE----------ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEeipEEELSLED-----------V 956

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  508 VDERKNMMEKIKQEErkvdglnknfkveqgkvmDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL 574
Cdd:TIGR02169  957 QAELQRVEEEIRALE------------------PVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 328-684 1.88e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 1.88e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  328 RQLRLKLVGLSQRIEELEETNKSLQ----KAEEELQELREKIAKGECGNSSLMAEVESLRKrvlEMEGKDEEITKTEAQC 403
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQselrRIENRLDELSQELSDASRKIGEIEKEIEQLEQ---EEEKLKERLEELEEDL 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  404 RELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRsksectqlHLNLEKEKNLTkdllNELEVVKSRVKELECSE 483
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA--------RLSHSRIPEIQ----AELSKLEEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  484 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFkveqgkvmdvtEKLIEESKKLLKLKSEMEEK 563
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK-----------EELEEELEELEAALRDLESR 883

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  564 VYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLD----GIEEVEREINR-GRSCKGSEFTCPEDNKIRELTLEIERL 638
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSelkaKLEALEEELSEiEDPKGEDEEIPEEELSLEDVQAELQRV 963

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1937928886  639 KKRLQQLEVVEgdlMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIK 684
Cdd:TIGR02169  964 EEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
337-787 4.15e-13

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 73.65  E-value: 4.15e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  337 LSQRIEELEETNKSLQKAEEELQELREKIAKgecgnssLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHH 416
Cdd:COG4717     76 LEEELKEAEEKEEEYAELQEELEELEEELEE-------LEAELEELREELEKLE-KLLQLLPLYQELEALEAELAELPER 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  417 SKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQL--HLNLEKEKNLtKDLLNELEVVKSRVKELecsESRLEKAELSLK 494
Cdd:COG4717    148 LEELEERLEELRELEEELEELEAELAELQEELEELleQLSLATEEEL-QDLAEELEELQQRLAEL---EEELEEAQEELE 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  495 DDLTKLKSFTVMLVDERKNmmEKIKQEER-------------KVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEME 561
Cdd:COG4717    224 ELEEELEQLENELEAAALE--ERLKEARLllliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLG 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  562 EKVYSLTK--ERDELMGKLRSE--EERSCELSCSVDLLKKRLDGIEEVEREINRGRSckgseftcpednkiRELTLEIER 637
Cdd:COG4717    302 KEAEELQAlpALEELEEEELEEllAALGLPPDLSPEELLELLDRIEELQELLREAEE--------------LEEELQLEE 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  638 LKKRLQQLevVEGDLMKTEDEYDQLEQKFRTEQDkanfLSQQLEEIKHQMAKH-KAIEKGEAVSQEAELRHRFRLEEAKS 716
Cdd:COG4717    368 LEQEIAAL--LAEAGVEDEEELRAALEQAEEYQE----LKEELEELEEQLEELlGELEELLEALDEEELEEELEELEEEL 441

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  717 RDLQAEVQALKEKIHELmnkEDQLSQLQVD--YSVLQQRFMEEETKNKNMGRE--VLNLTKEL--ELSKRYSRALRP 787
Cdd:COG4717    442 EELEEELEELREELAEL---EAELEQLEEDgeLAELLQELEELKAELRELAEEwaALKLALELleEAREEYREERLP 515
PTZ00121 PTZ00121
MAEBL; Provisional
 33-570 5.19e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.02  E-value: 5.19e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   33 SEDAKKNKANRKEEDVMASGTIKR---HLKPSGESEKKTKKSVELSKEDLIQLLSIMEGELQAREDvihmlRTEKTKPEV 109
Cdd:PTZ00121  1292 ADEAKKAEEKKKADEAKKKAEEAKkadEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD-----EAEAAEEKA 1366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  110 LEAHYGSAEPEKVLRVLHRDAilaQEKSIGEDVYEKPISELDRLEE-KQKETYRRMLEQLLLAEKCHRRTvyeleNEKHK 188
Cdd:PTZ00121  1367 EAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADElKKAAAAKKKADEAKKKAEEKKKA-----DEAKK 1438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  189 HTDYMNKSDDFTNLLEQER---ERLKKLLEQEKAYQARKEKENAKRLNKLRD--ELVKLKSFALMLVDERQMHIEQLGLQ 263
Cdd:PTZ00121  1439 KAEEAKKADEAKKKAEEAKkaeEAKKKAEEAKKADEAKKKAEEAKKADEAKKkaEEAKKKADEAKKAAEAKKKADEAKKA 1518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  264 SQKVQdlTQKLREEEEKLKAVTYKSKEDRQKLLKLEvdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEE 343
Cdd:PTZ00121  1519 EEAKK--ADEAKKAEEAKKADEAKKAEEKKKADELK-----KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE 1591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  344 --LEETNKSLQ-----KAEEELQELREKIAKGECGNSS-LMAEVESLRKRVLEMEGKDEEITKTEAQCR----ELKKKLQ 411
Cdd:PTZ00121  1592 arIEEVMKLYEeekkmKAEEAKKAEEAKIKAEELKKAEeEKKKVEQLKKKEAEEKKKAEELKKAEEENKikaaEEAKKAE 1671

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  412 EEEHHSKELRLEVEKLQKRMSELEKLEEafsrSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEC-SESRLEKAE 490
Cdd:PTZ00121  1672 EDKKKAEEAKKAEEDEKKAAEALKKEAE----EAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKeAEEDKKKAE 1747

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  491 LSLKDDLTK-----LKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQ--GKVMDVTEKLIEESKKLLKLKSEMEEK 563
Cdd:PTZ00121  1748 EAKKDEEEKkkiahLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKkiKDIFDNFANIIEGGKEGNLVINDSKEM 1827


                   ....*..
gi 1937928886  564 VYSLTKE 570
Cdd:PTZ00121  1828 EDSAIKE 1834
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 212-776 1.27e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 72.36  E-value: 1.27e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  212 KLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfaLMLVDERQMH-----IEQLGLQSQKVQDLTQKLREEEEKLKAVTY 286
Cdd:TIGR04523   78 KILEQQIKDLNDKLKKNKDKINKLNSDLSKINS--EIKNDKEQKNkleveLNKLEKQKKENKKNIDKFLTEIKKKEKELE 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  287 KSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVglsqRIEELEETNKSLQKaeeELQELREKia 366
Cdd:TIGR04523  156 KLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS----NLKKKIQKNKSLES---QISELKKQ-- 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  367 kgecgNSSLMAEVESLRKrvlEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLeeaFSRSKS 446
Cdd:TIGR04523  227 -----NNQLKDNIEKKQQ---EINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQ---LNQLKS 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  447 ECtqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD 526
Cdd:TIGR04523  296 EI--SDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  527 GLNKNfkveqgkvmdvTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRldgIEEVE 606
Cdd:TIGR04523  374 KLKKE-----------NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKET---IIKNN 439

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  607 REInrgrsckgSEFTcpedNKIRELTLEIERLKKRL----QQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 682
Cdd:TIGR04523  440 SEI--------KDLT----NQDSVKELIIKNLDNTResleTQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  683 IKHQMAKHKAiEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIH------ELMNKEDQLSQLQVDYSVLQQRFME 756
Cdd:TIGR04523  508 LEEKVKDLTK-KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkenlekEIDEKNKEIEELKQTQKSLKKKQEE 586

                          570       580
                   ....*....|....*....|
gi 1937928886  757 EETKNKNMGREVLNLTKELE 776
Cdd:TIGR04523  587 KQELIDQKEKEKKDLIKEIE 606
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
327-757 1.76e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 72.02  E-value: 1.76e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  327 NRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKgecgnssLMAEVESLRKRVLEMEgkdEEITKTEAQCREL 406
Cdd:PRK03918   143 SDESREKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEK-------FIKRTENIEELIKEKE---KELEEVLREINEI 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  407 KKKLqeeehhsKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL 486
Cdd:PRK03918   213 SSEL-------PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  487 EKAElSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVtEKLIEESKKLLKLKSEMEEKVYS 566
Cdd:PRK03918   286 KELK-EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-EELKKKLKELEKRLEELEERHEL 363

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  567 LTKERDELMGKLRSEEERSC----ELSCSVDLLKKRLDGIEEVEREINRGRS---------------CKGSEFTCP---- 623
Cdd:PRK03918   364 YEEAKAKKEELERLKKRLTGltpeKLEKELEELEKAKEEIEEEISKITARIGelkkeikelkkaieeLKKAKGKCPvcgr 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  624 ------EDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRtEQDKANFLSQQLEEIKHQMAKHKaIEKGE 697
Cdd:PRK03918   444 elteehRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKES-ELIKLKELAEQLKELEEKLKKYN-LEELE 521

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1937928886  698 AVSQEAE-LRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEE 757
Cdd:PRK03918   522 KKAEEYEkLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL 582
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 151-798 8.26e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.15  E-value: 8.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  151 DRLEEKQKETYRRMleQLLLAEKCHR--RTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 228
Cdd:pfam15921  245 DQLEALKSESQNKI--ELLLQQHQDRieQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  229 AKRLNKLRDELVKLKSfalMLVDErqmhIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLkleVDFEHKASR 308
Cdd:pfam15921  323 ESTVSQLRSELREAKR---MYEDK----IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLL---ADLHKREKE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  309 FSQEHEEmNAKLANQESHNR----QLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGN----SSLMAEVE 380
Cdd:pfam15921  393 LSLEKEQ-NKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESlekvSSLTAQLE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  381 S----LRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR----MSELEKL---EEAFSRSKSECT 449
Cdd:pfam15921  472 StkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdlkLQELQHLkneGDHLRNVQTECE 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  450 QLHLNLEKEKNLTKDLLNELEVVKSRVKE--LECSESRLEKAEL--SLKDDLTKLKSFTVMlvDERKNmmEKIKQEERKV 525
Cdd:pfam15921  552 ALKLQMAEKDKVIEILRQQIENMTQLVGQhgRTAGAMQVEKAQLekEINDRRLELQEFKIL--KDKKD--AKIRELEARV 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  526 DGLNKnfkveqgkvmdvteklieESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRL-DGIEE 604
Cdd:pfam15921  628 SDLEL------------------EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFrNKSEE 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  605 VEREINRGRSckgseftcpednKIRELTLEIERLKKRLQQLEVVEGDLMKT----EDEYDQLEQKFRTEQDKANFLSQQL 680
Cdd:pfam15921  690 METTTNKLKM------------QLKSAQSELEQTRNTLKSMEGSDGHAMKVamgmQKQITAKRGQIDALQSKIQFLEEAM 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  681 EEIKHQmaKHKAIEKGEAVSQEAELRHRFRLEEAKSRD-LQAEVQALKEKIhelMNKEDQLSQLQVDYSVLQQRFMEEET 759
Cdd:pfam15921  758 TNANKE--KHFLKEEKNKLSQELSTVATEKNKMAGELEvLRSQERRLKEKV---ANMEVALDKASLQFAECQDIIQRQEQ 832

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1937928886  760 KNKNMGREVLNLTKELE------LSKRYSRALRPSGNGRRMVDVP 798
Cdd:pfam15921  833 ESVRLKLQHTLDVKELQgpgytsNSSMKPRLLQPASFTRTHSNVP 877
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 394-740 1.60e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 1.60e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  394 EEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVvk 473
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA-- 761

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  474 srvkELECSESRLEKAELSLKDDLTKLKSftvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKL 553
Cdd:TIGR02168  762 ----EIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  554 LKLKSEMEEKVYSLTKERDElmgklrseeerscelscsvdllkkrldgIEEVEREINRGRSckgseftcpednKIRELTL 633
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSED----------------------------IESLAAEIEELEE------------LIEELES 873

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  634 EIERLKKRLQQLEVvegDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKAiEKGEAVSQEAELRHRFRLE- 712
Cdd:TIGR02168  874 ELEALLNERASLEE---ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL-RLEGLEVRIDNLQERLSEEy 949

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 1937928886  713 -------EAKSRDLQAEVQALKEKIHELMNKEDQL 740
Cdd:TIGR02168  950 sltleeaEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 193-611 2.94e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.16  E-value: 2.94e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  193 MNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfalmLVDERQMHIEQLGLQSQKVQDLTQ 272
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLA 736

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  273 KLREEEEKLkavtykskedrqkllklevdfEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETnksLQ 352
Cdd:TIGR02168  737 RLEAEVEQL---------------------EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ---IE 792

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  353 KAEEELQELREKIakgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEehhSKELRLEVEKLQKRMS 432
Cdd:TIGR02168  793 QLKEELKALREAL-------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ---IEELSEDIESLAAEIE 862

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  433 ELEKLEEAfsrsksectqlhlnLEKEknlTKDLLNELEVVKSRVKELecsESRLEKAELSLKDDLTKLKSftvmLVDERK 512
Cdd:TIGR02168  863 ELEELIEE--------------LESE---LEALLNERASLEEALALL---RSELEELSEELRELESKRSE----LRRELE 918

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  513 NMMEKIKQEERKVDGLNKNFKVEQGKVM----DVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL-------MGKLRSE 581
Cdd:TIGR02168  919 ELREKLAQLELRLEGLEVRIDNLQERLSeeysLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEEL 998

                          410       420       430
                   ....*....|....*....|....*....|
gi 1937928886  582 EERSCELSCSVDLLKKRLDGIEEVEREINR 611
Cdd:TIGR02168  999 KERYDFLTAQKEDLTEAKETLEEAIEEIDR 1028
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 127-786 3.19e-11

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 67.82  E-value: 3.19e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  127 HRDAILAQEKSIGEDVYEKPISELdRLEEKQKETYRRMLEQL-------LLAEKCHRR----TVYELENEKHKHTdYMNK 195
Cdd:pfam05483  111 NRKIIEAQRKAIQELQFENEKVSL-KLEEEIQENKDLIKENNatrhlcnLLKETCARSaektKKYEYEREETRQV-YMDL 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  196 SDDFTNLLeQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLksfalmlVDERQMHIEQLGLQS----QKVQDLT 271
Cdd:pfam05483  189 NNNIEKMI-LAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE-------INDKEKQVSLLLIQItekeNKMKDLT 260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  272 QKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSL 351
Cdd:pfam05483  261 FLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEEL 340

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  352 QKAEEELQELREKIAKGECGNSSLM-AEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRL---EVEKL 427
Cdd:pfam05483  341 NKAKAAHSFVVTEFEATTCSLEELLrTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKilaEDEKL 420

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  428 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEknlTKDLLNELEVVKSR----VKELECSESRLEKAEL---SLKDDLTKL 500
Cdd:pfam05483  421 LDEKKQFEKIAEELKGKEQELIFLLQAREKE---IHDLEIQLTAIKTSeehyLKEVEDLKTELEKEKLkniELTAHCDKL 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  501 KSFTVMLVDERKNMMEKIKQEERKVDglnkNFKVEQGKVMDVTEKLIEeskKLLKLKSEMEEKVYSLTKERDELMGKLRS 580
Cdd:pfam05483  498 LLENKELTQEASDMTLELKKHQEDII----NCKKQEERMLKQIENLEE---KEMNLRDELESVREEFIQKGDEVKCKLDK 570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  581 EEERSCELSCSVDLLKKRLDGIEEVEREINRGRSCKgseftcpeDNKIRELTLEIERLKKR----LQQLEVVEGDLMKTE 656
Cdd:pfam05483  571 SEENARSIEYEVLKKEKQMKILENKCNNLKKQIENK--------NKNIEELHQENKALKKKgsaeNKQLNAYEIKVNKLE 642

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  657 DEYDQLEQKFrteQDKANFLSQQLEEIKHQMAK-HKAIEKGEAVSQEAelrhrFRLEEAKSRDLQ---AEVQALKEKIHE 732
Cdd:pfam05483  643 LELASAKQKF---EEIIDNYQKEIEDKKISEEKlLEEVEKAKAIADEA-----VKLQKEIDKRCQhkiAEMVALMEKHKH 714

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1937928886  733 LMNK--EDQLSQLQVDYSVLQQRFMEE---ETKNKNMGREVLNLTKELELSKRYSRALR 786
Cdd:pfam05483  715 QYDKiiEERDSELGLYKNKEQEQSSAKaalEIELSNIKAELLSLKKQLEIEKEEKEKLK 773
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 404-780 6.18e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 6.18e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  404 RELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLtkdLLNELEVVKSRVKELECSE 483
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLEELEEDL 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  484 SRLEKAELSLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLnknfkvEQGKVMDVTEKLIEESKKLLKLKSEMEEK 563
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEA-------RIEELEEDLHKLEEALNDL------EARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  564 VYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRldgIEEVEREINRGRSckgseftcpednKIRELTLEIERLKKRLQ 643
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ---IKSIEKEIENLNG------------KKEELEEELEELEAALR 878

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  644 QLEVVEGDLMKtedEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKAiEKGEAVSQEAELRHRFRL------EEAKSR 717
Cdd:TIGR02169  879 DLESRLGDLKK---ERDELEAQLRELERKIEELEAQIEKKRKRLSELKA-KLEALEEELSEIEDPKGEdeeipeEELSLE 954

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  718 DLQAEVQALKEKIHEL----MNKEDQLSQLQVDYSVLQQRFMEEETKNKnmgrEVLNLTKELELSKR 780
Cdd:TIGR02169  955 DVQAELQRVEEEIRALepvnMLAIQEYEEVLKRLDELKEKRAKLEEERK----AILERIEEYEKKKR 1017
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
120-747 8.24e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 66.86  E-value: 8.24e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  120 EKVLRVLHRDAILAQEKSIGEDVY----EKP--ISELDRLEEkQKETYRRMLEQLLLAEKCHRRtvyeLENEKHKHTDYM 193
Cdd:COG4913    191 EKALRLLHKTQSFKPIGDLDDFVReymlEEPdtFEAADALVE-HFDDLERAHEALEDAREQIEL----LEPIRELAERYA 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  194 NKSDDFtNLLEQERERLKKLLEQEKAYQARKEKENAKR-LNKLRDELVKLKS-FALMLVDERQMHIEQLGLQSQKVQDLT 271
Cdd:COG4913    266 AARERL-AELEYLRAALRLWFAQRRLELLEAELEELRAeLARLEAELERLEArLDALREELDELEAQIRGNGGDRLEQLE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  272 QKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRlklvglsqriEELEETNKSL 351
Cdd:COG4913    345 REIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE----------EALAEAEAAL 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  352 QKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLemegkdEEITKTEAQCR---ELKKKLQEEEH---------HSKE 419
Cdd:COG4913    415 RDLRRELRELEAEIASLERRKSNIPARLLALRDALA------EALGLDEAELPfvgELIEVRPEEERwrgaiervlGGFA 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  420 LRLEVEklqkrmselEKLEEAFSRS-KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE---KAELSlkd 495
Cdd:COG4913    489 LTLLVP---------PEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRawlEAELG--- 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  496 dltklKSFTVMLVDERknmmEKIKQEERKV--DGL----------NKNFKVEQGKVM--DVTEKLIEESKKLLKLKSEME 561
Cdd:COG4913    557 -----RRFDYVCVDSP----EELRRHPRAItrAGQvkgngtrhekDDRRRIRSRYVLgfDNRAKLAALEAELAELEEELA 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  562 EkvysLTKERDELMGKLRSEEERSCELSCSVDLLKKRLD------GIEEVEREINRGRSckgseftcpEDNKIRELTLEI 635
Cdd:COG4913    628 E----AEERLEALEAELDALQERREALQRLAEYSWDEIDvasaerEIAELEAELERLDA---------SSDDLAALEEQL 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  636 ERLKKRLQQLevvegdlmktEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAkhkAIEKGEAVSQEAELRHRF------ 709
Cdd:COG4913    695 EELEAELEEL----------EEELDELKGEIGRLEKELEQAEEELDELQDRLE---AAEDLARLELRALLEERFaaalgd 761

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1937928886  710 RLEEAKSRDLQAEVQALKEKIHelmNKEDQLSQLQVDY 747
Cdd:COG4913    762 AVERELRENLEERIDALRARLN---RAEEELERAMRAF 796
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
297-743 1.86e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.45  E-value: 1.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  297 KLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLM 376
Cdd:PRK02224   199 KEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  377 AEVESLRKRVLEMEgkdEEITKTEAQCrELKkklqeeehhskelRLEVEKLQKRMSELEKLEEAFSRSKSECTQlhlnle 456
Cdd:PRK02224   279 EEVRDLRERLEELE---EERDDLLAEA-GLD-------------DADAEAVEARREELEDRDEELRDRLEECRV------ 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  457 keknLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSftvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQ 536
Cdd:PRK02224   336 ----AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERFGDAPVDL 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  537 GKVMDVTEKLIEEskkllklKSEMEEKVYSLTKERDELMGKLRSEEE-----------RSCELSCSVDLLKKRLDGIEEV 605
Cdd:PRK02224   408 GNAEDFLEELREE-------RDELREREAELEATLRTARERVEEAEAlleagkcpecgQPVEGSPHVETIEEDRERVEEL 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  606 EREINrgrsckgseftcpednkirELTLEIERLKKRLQQLEvvegDLMKTEDEYDQLEQKFRT-------EQDKANFLSQ 678
Cdd:PRK02224   481 EAELE-------------------DLEEEVEEVEERLERAE----DLVEAEDRIERLEERREDleeliaeRRETIEEKRE 537

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937928886  679 QLEEIKHQMAKHKA-IEKGEAVSQEAELRHRFRLEEAKsrDLQAEVQALKEKIHELMNKEDQLSQL 743
Cdd:PRK02224   538 RAEELRERAAELEAeAEEKREAAAEAEEEAEEAREEVA--ELNSKLAELKERIESLERIRTLLAAI 601
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 340-809 2.36e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 2.36e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  340 RIEELEETNKSLQKAEEELQELREKIAKgecgNSSLMAEVESLRKRVLEMEGKDEEItkteaqcRELKKKLQEEE----- 414
Cdd:TIGR02169  161 EIAGVAEFDRKKEKALEELEEVEENIER----LDLIIDEKRQQLERLRREREKAERY-------QALLKEKREYEgyell 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  415 HHSKELRLEVEKLQKRMSELEKLEEAFSRSKSEctqlhlnLEKEKNLTKDLLNELEvvkSRVKELECSESRLEKAEL-SL 493
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISE-------LEKRLEEIEQLLEELN---KKIKDLGEEEQLRVKEKIgEL 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  494 KDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLnknfkveQGKVMDVTEKLIEESKKLLKLKSEMEEKvysltkeRDE 573
Cdd:TIGR02169  300 EAEIASLERSIAEKERELEDAEERLAKLEAEIDKL-------LAEIEELEREIEEERKRRDKLTEEYAEL-------KEE 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  574 LMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINrgrsckgseftcpedNKIRELTLEIERLKKRLQQLEVVEGDLM 653
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN---------------ELKRELDRLQEELQRLSEELADLNAAIA 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  654 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKhkaiekgeavsqeaelrhrfrlEEAKSRDLQAEVQALKEKIHEL 733
Cdd:TIGR02169  431 GIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK----------------------YEQELYDLKEEYDRVEKELSKL 488

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1937928886  734 MNKEDQL-SQLQVDYSVLQQRFMEEETKNKNmGREVLNLTKEL-ELSKRYSRALRPSGnGRRMVDVPVASTGVQTEAV 809
Cdd:TIGR02169  489 QRELAEAeAQARASEERVRGGRAVEEVLKAS-IQGVHGTVAQLgSVGERYATAIEVAA-GNRLNNVVVEDDAVAKEAI 564
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
202-759 2.48e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 2.48e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  202 LLEQERERLKKLLEQekaYQARKEKENAKRLNKLRDELVKL----------KSFALMLVDERQMHIEQLGLQSQKVQDLT 271
Cdd:PRK02224   181 VLSDQRGSLDQLKAQ---IEEKEEKDLHERLNGLESELAELdeeieryeeqREQARETRDEADEVLEEHEERREELETLE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  272 QKLREEEEKlKAVTYKSKED--------RQKLLKLEVDFEH----------KASRFSQEHEEMNAKLANQESHNRQLRLK 333
Cdd:PRK02224   258 AEIEDLRET-IAETEREREElaeevrdlRERLEELEEERDDllaeaglddaDAEAVEARREELEDRDEELRDRLEECRVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  334 LV-------GLSQRIEELEETNKSLQKA----EEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQ 402
Cdd:PRK02224   337 AQahneeaeSLREDADDLEERAEELREEaaelESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEE 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  403 CRELKKKLQEEEhhsKELRLEVEKLQKRMSELEKLEEAfsRSKSECTQ-----LHLN-LEKEKNLTKDLLNELEVVKSRV 476
Cdd:PRK02224   417 LREERDELRERE---AELEATLRTARERVEEAEALLEA--GKCPECGQpvegsPHVEtIEEDRERVEELEAELEDLEEEV 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  477 KELecsESRLEKAElslkdDLTKLKSFTVMLVDERKNMMEKIKQEERKVDglnknfkveqgkvmDVTEKLIEESKKLLKL 556
Cdd:PRK02224   492 EEV---EERLERAE-----DLVEAEDRIERLEERREDLEELIAERRETIE--------------EKRERAEELRERAAEL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  557 KSEMEEKVYSLTKERDElmgklrSEEERSCELSCSVDL--LKKRLDGIEEVEREINRgrsckgseftcpednkIRELTLE 634
Cdd:PRK02224   550 EAEAEEKREAAAEAEEE------AEEAREEVAELNSKLaeLKERIESLERIRTLLAA----------------IADAEDE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  635 IERLKKRLQQLEVVEgdlmktedeyDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKaieKGEAVSQEAELRHRFRLEEA 714
Cdd:PRK02224   608 IERLREKREALAELN----------DERRERLAEKRERKRELEAEFDEARIEEARED---KERAEEYLEQVEEKLDELRE 674

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1937928886  715 KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEET 759
Cdd:PRK02224   675 ERDDLQAEIGAVENELEELEELRERREALENRVEALEALYDEAEE 719
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 152-768 3.17e-10

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 64.68  E-value: 3.17e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  152 RLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERL-----KKLLEQEKAYQARKEK 226
Cdd:TIGR00606  287 ELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELlveqgRLQLQADRHQEHIRAR 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  227 ENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKA 306
Cdd:TIGR00606  367 DSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKK 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  307 SRFSQEHEEMNAKLANQEshnrqlrlKLVGLSQRIEELEEtnkSLQKAEEELQELREKiakgecgnsslmAEVESLRKRV 386
Cdd:TIGR00606  447 EILEKKQEELKFVIKELQ--------QLEGSSDRILELDQ---ELRKAERELSKAEKN------------SLTETLKKEV 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  387 LEMEGKDEEITKTEaqcRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECT----------QLHLNLE 456
Cdd:TIGR00606  504 KSLQNEKADLDRKL---RKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTsllgyfpnkkQLEDWLH 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  457 KEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKL--KSFTVMLVDERKNMMEKIKQEERKV--------- 525
Cdd:TIGR00606  581 SKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYedKLFDVCGSQDEESDLERLKEEIEKSskqramlag 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  526 -----DGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLD 600
Cdd:TIGR00606  661 atavySQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIID 740

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  601 GIEEVEREInRGRSCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRTEQDKANFLSQQ 679
Cdd:TIGR00606  741 LKEKEIPEL-RNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDvERKIAQQAAKLQGSD 819

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  680 LEEIKHQMAKHK--AIEKGEAVSQEAELRHRFrleeakSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEE 757
Cdd:TIGR00606  820 LDRTVQQVNQEKqeKQHELDTVVSKIELNRKL------IQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVEL 893

                          650
                   ....*....|.
gi 1937928886  758 ETKNKNMGREV 768
Cdd:TIGR00606  894 STEVQSLIREI 904
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 180-779 7.87e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 7.87e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  180 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKlleqekayQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMH--I 257
Cdd:pfam02463  172 KEALKKLIEETENLAELIIDLEELKLQELKLKE--------QAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDllQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  258 EQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASrfsqeheemnaKLANQESHNRQLRLKLVGL 337
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAK-----------EEEELKSELLKLERRKVDD 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  338 SQRIEELEETNKSLQKAEEELQELREKIAKgecgnsslmaEVESLRKRVLEMEgkdeeiTKTEAQCRELKKKLQEEEHHS 417
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEK----------ELKELEIKREAEE------EEEEELEKLQEKLEQLEEELL 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  418 KELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEvvksrvKELECSESRLEKAELSLKDDL 497
Cdd:pfam02463  377 AKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEEL------EILEEEEESIELKQGKLTEEK 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  498 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGK 577
Cdd:pfam02463  451 EELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGR 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  578 LRSEEErsCELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPED-NKIRELTLEIERLKKRLQQLEVVEGDLMKTE 656
Cdd:pfam02463  531 LGDLGV--AVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGaRKLRLLIPKLKLPLKSIAVLEIDPILNLAQL 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  657 DEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKAIEKGEAVSQEAEL---RHRFRLEEAKSRDLQAEVQALKEKIHEL 733
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGlaeKSEVKASLSELTKELLEIQELQEKAESE 688

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1937928886  734 MNKEDQLSQLQvDYSVLQQRFMEEETKNKNMGREVLNLTKELELSK 779
Cdd:pfam02463  689 LAKEEILRRQL-EIKKKEQREKEELKKLKLEAEELLADRVQEAQDK 733
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
262-727 1.26e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.48  E-value: 1.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  262 LQSQKVQDLTQKLREEEEKLKAVtYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNR--QLRLKLVGLSQ 339
Cdd:COG4717     68 LNLKELKELEEELKEAEEKEEEY-AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEleALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  340 RIEELEEtnkslqkAEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMegKDEEITKTEAQCRELKKKLQEEEHHSKE 419
Cdd:COG4717    147 RLEELEE-------RLEELRELEEELEELEAELAELQEELEELLEQLSLA--TEEELQDLAEELEELQQRLAELEEELEE 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  420 LRLEVEKLQKRMSELEKleeafsrsksecTQLHLNLEKEKNLTKDLLneleVVKSRVKELECSESRLEKAELSLKDDLTK 499
Cdd:COG4717    218 AQEELEELEEELEQLEN------------ELEAAALEERLKEARLLL----LIAAALLALLGLGGSLLSLILTIAGVLFL 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  500 LKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKL---IEESKKLLKLKSEMEEKVYSLTKERDELMG 576
Cdd:COG4717    282 VLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALglpPDLSPEELLELLDRIEELQELLREAEELEE 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  577 KLRSEEersCELSCSVDLLKKRLDGIEEVEREINRGRsckgseftcpednKIRELTLEIERLKKRLQQLEVVEGDLMKTE 656
Cdd:COG4717    362 ELQLEE---LEQEIAALLAEAGVEDEEELRAALEQAE-------------EYQELKEELEELEEQLEELLGELEELLEAL 425

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1937928886  657 DEyDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKA-IEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALK 727
Cdd:COG4717    426 DE-EELEEELEELEEELEELEEELEELREELAELEAeLEQLEEDGELAELLQELEELKAELRELAEEWAALK 496
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
144-521 1.16e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.69  E-value: 1.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  144 EKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR 223
Cdd:PRK03918   334 EEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITAR 413

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  224 KE--KENAKRLNKLRDELVKLKSFA------------LMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSK 289
Cdd:PRK03918   414 IGelKKEIKELKKAIEELKKAKGKCpvcgrelteehrKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKES 493

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  290 EDR--QKLLKLEVDFEHKASRFSQEHEEMNAKLA-NQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIA 366
Cdd:PRK03918   494 ELIklKELAEQLKELEEKLKKYNLEELEKKAEEYeKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELA 573

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  367 K-----GECGNSSL------MAEVESLRKRVL-------EMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQ 428
Cdd:PRK03918   574 EllkelEELGFESVeeleerLKELEPFYNEYLelkdaekELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELE 653

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  429 KRMSELE---------KLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEcsesRLEKAELSLKDDLTK 499
Cdd:PRK03918   654 KKYSEEEyeelreeylELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE----KLEKALERVEELREK 729

                          410       420
                   ....*....|....*....|..
gi 1937928886  500 LKSFTVMLVDERKNMMEKIKQE 521
Cdd:PRK03918   730 VKKYKALLKERALSKVGEIASE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 152-451 1.46e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 1.46e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  152 RLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQekayQARKEKENAKR 231
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ----LKEELKALREA 804

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  232 LNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQ 311
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  312 EHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAkgecgnsSLMAEVESLRKRVLEM-- 389
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID-------NLQERLSEEYSLTLEEae 957

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937928886  390 ---EGKDEEITKTEAQCRELKKKLQE---------EEHHSKELRLEVEKLQKR--MSELEKLEEAFSRSKSECTQL 451
Cdd:TIGR02168  958 aleNKIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKERYDFLTAQKEdlTEAKETLEEAIEEIDREARER 1033
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 236-776 2.28e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 58.60  E-value: 2.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  236 RDELVKLKSFALMLVDE-RQMHIEQ---LGLQSQKVQDLTQKLREEEEKLKAVtykskedrQKLLKLEVDFEHKASRFSQ 311
Cdd:pfam05557    1 RAELIESKARLSQLQNEkKQMELEHkraRIELEKKASALKRQLDRESDRNQEL--------QKRIRLLEKREAEAEEALR 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  312 EHEEMN-AKLANQESHNRQLRLKlvglSQRIEELEETNKSLQKaeeELQELREKIAKGECGNSSLMAEVESLRKR----- 385
Cdd:pfam05557   73 EQAELNrLKKKYLEALNKKLNEK----ESQLADAREVISCLKN---ELSELRRQIQRAELELQSTNSELEELQERldllk 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  386 ---------VLEMEGKDEEITKTEAQCRELKKKLQEEEHHS---KELRLEVEKLQKRMSELEKLEE--AFSRSKSECTQL 451
Cdd:pfam05557  146 akaseaeqlRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSeivKNSKSELARIPELEKELERLREhnKHLNENIENKLL 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  452 hlnLEKEKNLTKDLLNELEVVKSRVKELECSESRLE-------KAELSLKDDLTK---LKSFTVMLVDERKNMMEKIKQE 521
Cdd:pfam05557  226 ---LKEEVEDLKRKLEREEKYREEAATLELEKEKLEqelqswvKLAQDTGLNLRSpedLSRRIEQLQQREIVLKEENSSL 302

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  522 ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS---EMEEKVYSLTKERDELMGKLRS------EEERSCELSCSV 592
Cdd:pfam05557  303 TSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKAlvrRLQRRVLLLTKERDGYRAILESydkeltMSNYSPQLLERI 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  593 ----DLLKKRLDGIEEVEREINRGRSCKGSEftcpednKIRELTLEIErLKKRLQQLEVveGDLMKTEDEYDQLEQKFRT 668
Cdd:pfam05557  383 eeaeDMTQKMQAHNEEMEAQLSVAEEELGGY-------KQQAQTLERE-LQALRQQESL--ADPSYSKEEVDSLRRKLET 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  669 EQDKANFLSQQLEEIKHQMAKHKAIEKGEAVSQEAeLRHR-------FRLEEAKSRDLQAEVQALKEKIHELMNKEDQLS 741
Cdd:pfam05557  453 LELERQRLREQKNELEMELERRCLQGDYDPKKTKV-LHLSmnpaaeaYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVL 531

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1937928886  742 QLQvdysvlqqrfmeeETKNKNMGREVLNLTKELE 776
Cdd:pfam05557  532 RLP-------------ETTSTMNFKEVLDLRKELE 553
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 181-776 2.42e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 58.65  E-value: 2.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  181 ELENEKHKHTDYMNKSDDFTNLLEQERerlKKLLEQEKAYQARKEKENAKRlNKLRDELV----KLKSFA---LMLVDER 253
Cdd:pfam01576   72 ELEEILHELESRLEEEEERSQQLQNEK---KKMQQHIQDLEEQLDEEEAAR-QKLQLEKVtteaKIKKLEediLLLEDQN 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  254 QMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEhKASRFSQEHEEMNAKLanqESHNRQLRLK 333
Cdd:pfam01576  148 SKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLK-KEEKGRQELEKAKRKL---EGESTDLQEQ 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  334 LVGLSQRIEELEetnKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLE----MEGKDEEITKTEAQCRELKKK 409
Cdd:pfam01576  224 IAELQAQIAELR---AQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISElqedLESERAARNKAEKQRRDLGEE 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  410 LQ----EEEHHSKELRLEVEKLQKRMSELEKLEEAF-SRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSES 484
Cdd:pfam01576  301 LEalktELEDTLDTTAAQQELRSKREQEVTELKKALeEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  485 RLEKAELSLKDDLTKLKSftvmlvderknmmekikqeeRKVDGLNKNFKVEqGKVMDVTEKLIEESKKllklKSEMEEKV 564
Cdd:pfam01576  381 ALESENAELQAELRTLQQ--------------------AKQDSEHKRKKLE-GQLQELQARLSESERQ----RAELAEKL 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  565 YSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPED--NKIRELTLEIERLKKRL 642
Cdd:pfam01576  436 SKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDerNSLQEQLEEEEEAKRNV 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  643 Q-QLEVVEGDLM----KTEDE---YDQLEQKFRTEQDKANFLSQQLEEikhqmaKHKAIEKGEavsqeaelRHRFRLEEa 714
Cdd:pfam01576  516 ErQLSTLQAQLSdmkkKLEEDagtLEALEEGKKRLQRELEALTQQLEE------KAAAYDKLE--------KTKNRLQQ- 580

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937928886  715 KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGRE----VLNLTKELE 776
Cdd:pfam01576  581 ELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREketrALSLARALE 646
COG5022 COG5022
Myosin heavy chain [General function prediction only];
188-585 3.40e-08

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 58.17  E-value: 3.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  188 KHTDYMNKSDDFTNL-----LEQERERLKKLLE-----QEKAYQARKEKENAKRLNKLRDELVKLKsFALMLVDERQMHI 257
Cdd:COG5022    785 RLVDYELKWRLFIKLqpllsLLGSRKEYRSYLAciiklQKTIKREKKLRETEEVEFSLKAEVLIQK-FGRSLKAKKRFSL 863

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  258 EQ---LGLQSQ-KVQDLTQKLREEEEKLKAVTY---KSKEDRQKLLKLEVDFEhkaSRFSQEHEEMNAKLANQESHNRQL 330
Cdd:COG5022    864 LKketIYLQSAqRVELAERQLQELKIDVKSISSlklVNLELESEIIELKKSLS---SDLIENLEFKTELIARLKKLLNNI 940

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  331 RLKlVGLSQRIEELEETNKsLQKAEEELQELREKIakgECGNSSLMAEVESLRKRVLEMEGKDEEITKTeaqcRELKKKL 410
Cdd:COG5022    941 DLE-EGPSIEYVKLPELNK-LHEVESKLKETSEEY---EDLLKKSTILVREGNKANSELKNFKKELAEL----SKQYGAL 1011

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  411 QEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNeLEVVKSRVKELECSESRLEKAE 490
Cdd:COG5022   1012 QESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKA-LKLRRENSLLDDKQLYQLESTE 1090

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  491 lslkddlTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFkveqgkvmdvteKLIEESKKLLKLKS---EMEEKVYSL 567
Cdd:COG5022   1091 -------NLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKL------------NLLQEISKFLSQLVntlEPVFQKLSV 1151

                          410
                   ....*....|....*...
gi 1937928886  568 TKERDELMGKLRSEEERS 585
Cdd:COG5022   1152 LQLELDGLFWEANLEALP 1169
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 34-587 4.36e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 57.67  E-value: 4.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   34 EDAKKNKANRKEEDVMASGTIKRHLKPSGESEKKTKKSVELSKEDLIQLLSIMEGELQAREDVIHMLRTEKTKPEVLEAH 113
Cdd:pfam02463  449 EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  114 YGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE-------K 186
Cdd:pfam02463  529 GRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDpilnlaqL 608

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  187 HKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQK 266
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE 688

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  267 VQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEE 346
Cdd:pfam02463  689 LAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL----LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEE 764

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  347 TNK--SLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEV 424
Cdd:pfam02463  765 EKSelSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKE 844

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  425 EKLQKRMSELEKLEEAFSRSKSECTQlHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA--------------E 490
Cdd:pfam02463  845 EQKLEKLAEEELERLEEEITKEELLQ-ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKlnlleekeneieerI 923

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  491 LSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKE 570
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003

                          570
                   ....*....|....*..
gi 1937928886  571 RDELMGKLRSEEERSCE 587
Cdd:pfam02463 1004 KKKLIRAIIEETCQRLK 1020
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 221-443 7.37e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 7.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  221 QARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEV 300
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  301 DFEHKASRFSQ---------EHEEMNAKLANQESHNRQLRLKLVG-----LSQRIEELEETNKSLQKAEEELQELREKIA 366
Cdd:COG4942     98 ELEAQKEELAEllralyrlgRQPPLALLLSPEDFLDAVRRLQYLKylapaRREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  367 KgecgnssLMAEVESLRKRVlemegkDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSR 443
Cdd:COG4942    178 A-------LLAELEEERAAL------EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 218-502 1.06e-07

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 56.59  E-value: 1.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  218 KAYQARKEKenakRLNKLRDELVKLKS---FALMLVDErqmhieQLGLQSQKVQDLTQKLReeeeKLKAVTYKSKEDRQK 294
Cdd:PTZ00108   991 DLYKKRKEY----LLGKLERELARLSNkvrFIKHVING------ELVITNAKKKDLVKELK----KLGYVRFKDIIKKKS 1056

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  295 LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQriEELEETNKSLQKAEEELQELREKIAKgecgnSS 374
Cdd:PTZ00108  1057 EKITAEEEEGAEEDDEADDEDDEEELGAAVSYDYLLSMPIWSLTK--EKVEKLNAELEKKEKELEKLKNTTPK-----DM 1129

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  375 LMAEVESLRKRVLEMEGKDEeitKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLN 454
Cdd:PTZ00108  1130 WLEDLDKFEEALEEQEEVEE---KEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEK 1206

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1937928886  455 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKS 502
Cdd:PTZ00108  1207 RKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSS 1254
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
339-440 1.77e-07

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 55.63  E-value: 1.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  339 QRIEELEETnksLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSK 418
Cdd:COG2433    413 EEIRRLEEQ---VERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRKDREISRLDREIERLERELEEERERIE 489

                           90       100
                   ....*....|....*....|..
gi 1937928886  419 ELRLEVEKLqKRMSELEKLEEA 440
Cdd:COG2433    490 ELKRKLERL-KELWKLEHSGEL 510
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 342-563 1.80e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 1.80e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  342 EELEETNKSLQKAEEELQELREKIAkgecgnsSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHSKELR 421
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEK-------ALLKQLAALERRIAALA---RRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  422 LEVEKLQKRMSELekLEEAFSRSKSECTQLHLN----------LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAEL 491
Cdd:COG4942     97 AELEAQKEELAEL--LRALYRLGRQPPLALLLSpedfldavrrLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1937928886  492 SLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLNKNFKVEQGKVmdvtEKLIEESKKLLKLKSEMEEK 563
Cdd:COG4942    175 ELEALLAELEE-------ERAALEALKAERQKLLARLEKELAELAAEL----AELQQEAEELEALIARLEAE 235
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 180-783 2.00e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.51  E-value: 2.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  180 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKLleQEKAYQARKEKENAKRLnkLRDELVKLKSFALMLVDERQMHIEQ 259
Cdd:pfam15921   57 YEVELDSPRKIIAYPGKEHIERVLEEYSHQVKDL--QRRLNESNELHEKQKFY--LRQSVIDLQTKLQEMQMERDAMADI 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  260 LGLQSQKVQDLTQKLREEEEKLKAVTyKSKEDR----------------------QKLLKLEVDFEHKASRFSQEHEEMN 317
Cdd:pfam15921  133 RRRESQSQEDLRNQLQNTVHELEAAK-CLKEDMledsntqieqlrkmmlshegvlQEIRSILVDFEEASGKKIYEHDSMS 211

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  318 A----KLANQESHN-RQLRLKLVGLSQRIEELEETNKSLQ-----KAEEELQELREK----IAKGECGNSSLMAEVESLR 383
Cdd:pfam15921  212 TmhfrSLGSAISKIlRELDTEISYLKGRIFPVEDQLEALKsesqnKIELLLQQHQDRieqlISEHEVEITGLTEKASSAR 291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  384 KRVLEMEGKDEEIT-KTEAQCRELKKKLQEEEHHSKELRLEVEKlQKRMSE--LEKLEEAFSRSKSECTQLHLNLEKEKN 460
Cdd:pfam15921  292 SQANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELRE-AKRMYEdkIEELEKQLVLANSELTEARTERDQFSQ 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  461 LTKDLLNELEVVKSRVKELEcSESRLEKAELSLKDDLTKLKSFTvmlVDERKNMMEKIKQEERKVDGLNKNFKVE-QGKV 539
Cdd:pfam15921  371 ESGNLDDQLQKLLADLHKRE-KELSLEKEQNKRLWDRDTGNSIT---IDHLRRELDDRNMEVQRLEALLKAMKSEcQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  540 ---MDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGK---LRSEEERSCELSCSvdlLKKRLDGIEEVEREINRGR 613
Cdd:pfam15921  447 erqMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKkmtLESSERTVSDLTAS---LQEKERAIEATNAEITKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  614 SckgseftcPEDNKIREltleierlkkrLQQLEVVEGDLMKTEDEYDQLEQKFrTEQDKA-NFLSQQLEEIKHQMAKHKA 692
Cdd:pfam15921  524 S--------RVDLKLQE-----------LQHLKNEGDHLRNVQTECEALKLQM-AEKDKViEILRQQIENMTQLVGQHGR 583

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  693 IEKG---EAVSQEAELRHRfRLE-----------EAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEE 758
Cdd:pfam15921  584 TAGAmqvEKAQLEKEINDR-RLElqefkilkdkkDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEV 662

                          650       660
                   ....*....|....*....|....*
gi 1937928886  759 TKNKNmgrEVLNLTKELELSKRYSR 783
Cdd:pfam15921  663 KTSRN---ELNSLSEDYEVLKRNFR 684
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 913-1177 3.06e-07

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 54.92  E-value: 3.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  913 VTP-----DHENSTATLEITSPTSeeffSSTTVIPTLGNQKPRITIiPSPNVMSqkpksadPTLGPERAMSPVTiTTISR 987
Cdd:pfam05109  488 VTPspsprDNGTESKAPDMTSPTS----AVTTPTPNATSPTPAVTT-PTPNATS-------PTLGKTSPTSAVT-TPTPN 554

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  988 EKSPEGGRSAFADRPASPIQIMTVSTSA--APTEIAVSPESQEV-PMGRTILKVTPEKQTVPAPVRKYNSNANIITTEDN 1064
Cdd:pfam05109  555 ATSPTPAVTTPTPNATIPTLGKTSPTSAvtTPTPNATSPTVGETsPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQH 634

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1065 KIHIHLGSQFKRSPGPAAEGVSPVITvrpVNVTAEKEVSTGTVLRSPRNHLSSRPGASKVTSTITITPVTTSSTRGTQSV 1144
Cdd:pfam05109  635 NITSSSTSSMSLRPSSISETLSPSTS---DNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG 711

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1937928886 1145 SGQDGSSQRP--------TPTRIPMS----KGMKAGKPVVAASGA 1177
Cdd:pfam05109  712 PGNSSTSTKPgevnvtkgTPPKNATSpqapSGQKTAVPTVTSTGG 756
PRK01156 PRK01156
chromosome segregation protein; Provisional
 147-709 3.36e-07

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 54.91  E-value: 3.36e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  147 ISELDRLEEKQKETYRRMLE---QLLLAEKCHRRTVYELENEKhkhTDYMNKSDDFtNLLEQERERLKKLLEQEKAYQAr 223
Cdd:PRK01156   182 ISNIDYLEEKLKSSNLELENikkQIADDEKSHSITLKEIERLS---IEYNNAMDDY-NNLKSALNELSSLEDMKNRYES- 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  224 KEKENAKRLNKLRDELVKLKSfalmlVDERQMHIE-------------------QLGLQSQKVQDLTQKLREEEEKLK-- 282
Cdd:PRK01156   257 EIKTAESDLSMELEKNNYYKE-----LEERHMKIIndpvyknrnyindyfkyknDIENKKQILSNIDAEINKYHAIIKkl 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  283 AVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLR------LKLVGLSQRIEELEETNKSLQKAEe 356
Cdd:PRK01156   332 SVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEeyskniERMSAFISEILKIQEIDPDAIKKE- 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  357 eLQELREKIAKGECGNSSLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEE--EHHSKELRLEVEKLQKRMSEL 434
Cdd:PRK01156   411 -LNEINVKLQDISSKVSSLNQRIRALRENLDELS-RNMEMLNGQSVCPVCGTTLGEEksNHIINHYNEKKSRLEEKIREI 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  435 EKLEEAFSRSKSECTQLHLNLEKEK-NLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERK- 512
Cdd:PRK01156   489 EIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRt 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  513 ---NMMEKIKQEErkVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS-------EMEEKVYSLTKERDELMGKLRSEE 582
Cdd:PRK01156   569 swlNALAVISLID--IETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSyidksirEIENEANNLNNKYNEIQENKILIE 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  583 ErsceLSCSVDLLKKRLDGIEEVEREINrgrsckgseftcpednkirELTLEIERLKKRLQQlevVEGDLMKTEDEYDQL 662
Cdd:PRK01156   647 K----LRGKIDNYKKQIAEIDSIIPDLK-------------------EITSRINDIEDNLKK---SRKALDDAKANRARL 700

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1937928886  663 EQKFRTEQDKANFLSQQLEEIKHQMAKHKAIEKgeAVSQEAELRHRF 709
Cdd:PRK01156   701 ESTIEILRTRINELSDRINDINETLESMKKIKK--AIGDLKRLREAF 745
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 201-518 4.55e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 4.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  201 NLLEQERERLKKLLEQEKAYQARKEKENA------KRLNKLRDEL-VKLKSFALMLVDERQ---MHIEQLGLQSQKVQDL 270
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEIKDLTNQDSvkeliiKNLDNTRESLeTQLKVLSRSINKIKQnleQKQKELKSKEKELKKL 501

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  271 TQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKlaNQESHNRQLRLKLVGLSQRIEELEETNKS 350
Cdd:TIGR04523  502 NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD--DFELKKENLEKEIDEKNKEIEELKQTQKS 579

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  351 LQKAEEELQELrekIAKGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKr 430
Cdd:TIGR04523  580 LKKKQEEKQEL---IDQKEKEKKDLIKEIEEKEKKISSLE---KELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE- 652

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  431 msELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEV-VKSRVKEL--ECSESRLEKAELSLKDDLTKLKSFTVML 507
Cdd:TIGR04523  653 --TIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLhYKKYITRMirIKDLPKLEEKYKEIEKELKKLDEFSKEL 730

                          330
                   ....*....|.
gi 1937928886  508 VDERKNMMEKI 518
Cdd:TIGR04523  731 ENIIKNFNKKF 741
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 273-774 4.96e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 4.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  273 KLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQeheeMNAKLANQESHNRQLRLKLVGLSQRIEELeetNKSLQ 352
Cdd:TIGR04523   34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINN----SNNKIKILEQQIKDLNDKLKKNKDKINKL---NSDLS 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  353 KAEEELQELREKIAKGEcgnsslmAEVESLRKrvlemegkdeEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMS 432
Cdd:TIGR04523  107 KINSEIKNDKEQKNKLE-------VELNKLEK----------QKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKE 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  433 ELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERK 512
Cdd:TIGR04523  170 ELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  513 NMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEME----EKVYSLTKE-RDELMGKLRSEEERSCE 587
Cdd:TIGR04523  250 NTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKElKSELKNQEKKLEEIQNQ 329

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  588 LSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPED--NKIRELTLEIERLKKRLQQLEV----VEGDLMKTEDEYDQ 661
Cdd:TIGR04523  330 ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEkqNEIEKLKKENQSYKQEIKNLESqindLESKIQNQEKLNQQ 409

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  662 LEQKFRTEQDKANFLSQQLEEIKHQMAKHKAiEKGEAVSQEAELRHRFRLEEAKSRDLQAEV-----------QALKEKI 730
Cdd:TIGR04523  410 KDEQIKKLQQEKELLEKEIERLKETIIKNNS-EIKDLTNQDSVKELIIKNLDNTRESLETQLkvlsrsinkikQNLEQKQ 488

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1937928886  731 HELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKE 774
Cdd:TIGR04523  489 KELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESE 532
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 22-754 5.84e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.07  E-value: 5.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   22 SIISSDGGKGPSEDAKKNKANRKEEDVMASGTIK--RHLKPSGESEKKTKKSVELSkedliqlLSIMEGELQAredviHM 99
Cdd:pfam12128  204 AILEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMkiRPEFTKLQQEFNTLESAELR-------LSHLHFGYKS-----DE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  100 LRTEKTKPEVLEahyGSAEPEKVLRVLHRD-----AILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLaekc 174
Cdd:pfam12128  272 TLIASRQEERQE---TSAELNQLLRTLDDQwkekrDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAA---- 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  175 hrrtvyELENEkhkhtdymnksDDFTNLLEQERERLKKLLEQ----EKAYQARKEK---ENAKRLNKLRDELVKLKSFAL 247
Cdd:pfam12128  345 ------DQEQL-----------PSWQSELENLEERLKALTGKhqdvTAKYNRRRSKikeQNNRDIAGIKDKLAKIREARD 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  248 MLVDERQMHIEQL----------GLQSQKVQDLTQKLREEEEKLK--AVTYKSKEDRQKllklevdfEHKASRFSQEHEE 315
Cdd:pfam12128  408 RQLAVAEDDLQALeselreqleaGKLEFNEEEYRLKSRLGELKLRlnQATATPELLLQL--------ENFDERIERAREE 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  316 MNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKI--------------AKGECGNSSLMAEVES 381
Cdd:pfam12128  480 QEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqagtllhflrkeAPDWEQSIGKVISPEL 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  382 LRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEH-----HSKELRLEVEK----LQKRMSELEKLEEAFSRSKSECTQLH 452
Cdd:pfam12128  560 LHRTDLDPE-VWDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKaeeaLQSAREKQAAAEEQLVQANGELEKAS 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  453 LNLEKEKNLTK---DLLNELEVVKSRVKeLECSESRlEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLN 529
Cdd:pfam12128  639 REETFARTALKnarLDLRRLFDEKQSEK-DKKNKAL-AERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  530 KNFKVEQGKVMDVTEKLIEESKklLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREI 609
Cdd:pfam12128  717 QAYWQVVEGALDAQLALLKAAI--AARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEV 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  610 NRGRSCKGSEFTCPEDN----------KIRELTLEIERL----KKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 675
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRlatqlsnierAISELQQQLARLiadtKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  676 L-----SQQLE-EIKHQMA---KHKAIEKGEAVSQEAELRHRFRLEEAKSRDLQAEV-QALKEKIHELMNKEDQLSQLQV 745
Cdd:pfam12128  875 LkedanSEQAQgSIGERLAqleDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLAETwESLREEDHYQNDKGIRLLDYRK 954


                   ....*....
gi 1937928886  746 DYSVLQQRF 754
Cdd:pfam12128  955 LVPYLEQWF 963
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 58-768 6.28e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.82  E-value: 6.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   58 LKPSGESEKKTKKSVELSKEDLIQLLSIME-GELQAREDVIHmlRTEKTKPEVLEAHYGSAE---PEKVLRVLHRDAILA 133
Cdd:TIGR00618  148 LLPQGEFAQFLKAKSKEKKELLMNLFPLDQyTQLALMEFAKK--KSLHGKAELLTLRSQLLTlctPCMPDTYHERKQVLE 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  134 QE-KSIGEDVYEKPISE--LDRLEEKQKETYR--RMLEQLLLAEKCHRRTVYELEN---------------EKHKHTDYM 193
Cdd:TIGR00618  226 KElKHLREALQQTQQSHayLTQKREAQEEQLKkqQLLKQLRARIEELRAQEAVLEEtqerinrarkaaplaAHIKAVTQI 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  194 NK--SDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRL--------NKLRDELVKLKSFALMLVDER---------Q 254
Cdd:TIGR00618  306 EQqaQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLlqtlhsqeIHIRDAHEVATSIREISCQQHtltqhihtlQ 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  255 MHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKL 334
Cdd:TIGR00618  386 QQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESA 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  335 VGLSQRIEELeETNKSLQKAEEELQELREKIAKGECGNSSLmaevesLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEE 414
Cdd:TIGR00618  466 QSLKEREQQL-QTKEQIHLQETRKKAVVLARLLELQEEPCP------LCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  415 HHSK-------ELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECsESRLE 487
Cdd:TIGR00618  539 QLETseedvyhQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC-EQHAL 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  488 KAELSLKDDLTKL--------KSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSE 559
Cdd:TIGR00618  618 LRKLQPEQDLQDVrlhlqqcsQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKE 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  560 MEEKVYSLTKERDELMGKLRSEEERSCELSCS-VDLLKKRLDGIEEVEREINRGRSCKGSEFTCPEDNKIRELTLEIERL 638
Cdd:TIGR00618  698 MLAQCQTLLRELETHIEEYDREFNEIENASSSlGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTG 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  639 kkrlqqlevvegdlmkteDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMakhkaiekgeavsqEAELRHRFRLEEAKSRD 718
Cdd:TIGR00618  778 ------------------AELSHLAAEIQFFNRLREEDTHLLKTLEAEI--------------GQEIPSDEDILNLQCET 825

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1937928886  719 LQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREV 768
Cdd:TIGR00618  826 LVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 798-1155 6.35e-07

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 53.77  E-value: 6.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  798 PVASTGVQTEAVCGDAAEEETPAVfirksfQEENHIMSNLRQVGLKKPMERSSVLDRyPPAANELTMRKSWIPWMRKREN 877
Cdd:pfam05109  425 PESTTTSPTLNTTGFAAPNTTTGL------PSSTHVPTNLTAPASTGPTVSTADVTS-PTPAGTTSGASPVTPSPSPRDN 497

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  878 GPSTPQEKGPRPNQGAGHPgelvlAPKQGQPLHIRVTPDHENSTATLEITSPTSeeffSSTTVIPTLGNqkpritiiPSP 957
Cdd:pfam05109  498 GTESKAPDMTSPTSAVTTP-----TPNATSPTPAVTTPTPNATSPTLGKTSPTS----AVTTPTPNATS--------PTP 560

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  958 NVMSQKPKSADPTLGPERAMSPVTITTISR------EKSPE--------GGRSA---FADRPASPIQIMTVS----TSAA 1016
Cdd:pfam05109  561 AVTTPTPNATIPTLGKTSPTSAVTTPTPNAtsptvgETSPQanttnhtlGGTSStpvVTSPPKNATSAVTTGqhniTSSS 640

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1017 PTEIAVSPESqevpMGRTILKVTPEKQTVPAPVRKY-----NSNANIITTEDNKIHIHLGSQFKRSPGPAAEGVSP---V 1088
Cdd:pfam05109  641 TSSMSLRPSS----ISETLSPSTSDNSTSHMPLLTSahptgGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPgnsS 716

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1089 ITVRPvnvtAEKEVSTGTvlrSPRNHLSSRPGASKVTS--TITITPVTTSSTRGTQSVSGQDG-SSQRPT 1155
Cdd:pfam05109  717 TSTKP----GEVNVTKGT---PPKNATSPQAPSGQKTAvpTVTSTGGKANSTTGGKHTTGHGArTSTEPT 779
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 189-776 8.21e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 53.90  E-value: 8.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  189 HTDYMNKSDDFTNLLEQERERL-KKLLEqekayqarKEKENAKRLNKLRDELvKLKSFALMLVDERQMHIEQLGLQSQKV 267
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEIGKNIELLnKEILE--------EAEINITNFNEIKEKL-KHYNFDDFGKEENIKYADEINKIKDDI 1120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  268 QDLTQKLREEEEKLKAVTYKSK----EDRQKLLKLEvdfehkasrfsqeheemnaKLANQESHNRQLRlklvGLSQRIEE 343
Cdd:TIGR01612 1121 KNLDQKIDHHIKALEEIKKKSEnyidEIKAQINDLE-------------------DVADKAISNDDPE----EIEKKIEN 1177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  344 LEETNKSLQKAEEELQELREKIAKGECGNSSL-------MAEVESLRKrvLEMEGKDEEITKTEAQCRELKKKLQEEEHh 416
Cdd:TIGR01612 1178 IVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLeevkginLSYGKNLGK--LFLEKIDEEKKKSEHMIKAMEAYIEDLDE- 1254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  417 SKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNE-LEVV-----KSRV----KELECSESRL 486
Cdd:TIGR01612 1255 IKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKsLKIIedfseESDIndikKELQKNLLDA 1334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  487 EKAELSLKDDLTKLKS-FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEqgkvMDVTEKLIEESKKLLKLKsEMEEKVY 565
Cdd:TIGR01612 1335 QKHNSDINLYLNEIANiYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDE----LDKSEKLIKKIKDDINLE-ECKSKIE 1409

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  566 SLTKERD---------ELMGKLRSEE-------ERSCELSCSVDLLKKRLDGIEEVEREINRGRSCKGsefTCPEDNKIR 629
Cdd:TIGR01612 1410 STLDDKDidecikkikELKNHILSEEsnidtyfKNADENNENVLLLFKNIEMADNKSQHILKIKKDNA---TNDHDFNIN 1486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  630 ELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLsqqleEIKHQMAKHKAiEKGEAVSQEAELRHRF 709
Cdd:TIGR01612 1487 ELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSAL-----AIKNKFAKTKK-DSEIIIKEIKDAHKKF 1560

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  710 RLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE 776
Cdd:TIGR01612 1561 ILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETE 1627
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 177-733 1.15e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 1.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  177 RTVYELENEKHKHTDYMNKSDDFTNLLEQE----RERLKKLLEQ-----EKAYQARKEKENAKRLNKLRDELVKLKSFAL 247
Cdd:TIGR00606  577 DWLHSKSKEINQTRDRLAKLNKELASLEQNknhiNNELESKEEQlssyeDKLFDVCGSQDEESDLERLKEEIEKSSKQRA 656

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  248 MLVDERQMH---IEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQE 324
Cdd:TIGR00606  657 MLAGATAVYsqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQ 736

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  325 SHnrqlrlklvgLSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVES---LRKRVLEMEGKDEEITKTEA 401
Cdd:TIGR00606  737 SI----------IDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESakvCLTDVTIMERFQMELKDVER 806

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  402 Q----------------CRELKKKLQEEEHHSKELRLEVEKLQK----RMSELEKLEEAFSRSKSECTQLHLNLEKEKNL 461
Cdd:TIGR00606  807 KiaqqaaklqgsdldrtVQQVNQEKQEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQF 886

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  462 TKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDglNKNFKveqgkvMD 541
Cdd:TIGR00606  887 EEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK--NIHGY------MK 958

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  542 VTEKLIEESKKLLKLKSEmeekvysltKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEft 621
Cdd:TIGR00606  959 DIENKIQDGKDDYLKQKE---------TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRE-- 1027

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  622 cpedNKIRELTLEIERLKKRLQQLEVVEgdlmkTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMakhkaiekgeaVSQ 701
Cdd:TIGR00606 1028 ----NELKEVEEELKQHLKEMGQMQVLQ-----MKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI-----------KHF 1087

                          570       580       590
                   ....*....|....*....|....*....|...
gi 1937928886  702 EAELRH-RFRLEEAKSRDLQAEVQALKEKIHEL 733
Cdd:TIGR00606 1088 KKELREpQFRDAEEKYREMMIVMRTTELVNKDL 1120
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 258-780 1.38e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.87  E-value: 1.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  258 EQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSqEHEEMNAKLANQEshnRQLRLKLVGL 337
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCA-EAEEMRARLAARK---QELEEILHEL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  338 SQRIEELEETNKSLQ----KAEEELQELREKIAKGECGNSSLM-------AEVESLRKRVLEMEGKDEEITKT----EAQ 402
Cdd:pfam01576   81 ESRLEEEEERSQQLQnekkKMQQHIQDLEEQLDEEEAARQKLQlekvtteAKIKKLEEDILLLEDQNSKLSKErkllEER 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  403 CRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELevvKSRVKELECS 482
Cdd:pfam01576  161 ISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL---QAQIAELRAQ 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  483 esrLEKAELSLKDDLTKLKSFTVmlvdERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 562
Cdd:pfam01576  238 ---LAKKEEELQAALARLEEETA----QKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELED 310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  563 KVYSLTKERDelmgkLRSEEERScelscsVDLLKKRLDgieeverEINRGRSCKGSEFTCPEDNKIRELTLEIERLKKRL 642
Cdd:pfam01576  311 TLDTTAAQQE-----LRSKREQE------VTELKKALE-------EETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNK 372

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  643 QQLE----VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEI--KHQMAKHKAIEKGEAVSQ-EAELR---HRFRLE 712
Cdd:pfam01576  373 ANLEkakqALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELqaRLSESERQRAELAEKLSKlQSELEsvsSLLNEA 452

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1937928886  713 EAKSRDLQAEVQALKEKIH---ELMNKEDQ--------LSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELELSKR 780
Cdd:pfam01576  453 EGKNIKLSKDVSSLESQLQdtqELLQEETRqklnlstrLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKK 531
PRK01156 PRK01156
chromosome segregation protein; Provisional
 337-764 3.18e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 51.44  E-value: 3.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  337 LSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHH 416
Cdd:PRK01156   192 LKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEK 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  417 SKELRLEVEKLQKRMS------------------ELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDlLNELEVVKSRVKE 478
Cdd:PRK01156   272 NNYYKELEERHMKIINdpvyknrnyindyfkyknDIENKKQILSNIDAEINKYHAIIKKLSVLQKD-YNDYIKKKSRYDD 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  479 LEcsesrlekaelSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 558
Cdd:PRK01156   351 LN-----------NQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQ 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  559 EMEEKVYSLTKERDELMGKLRSEEERSCELS----CSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPEdNKIRELTLE 634
Cdd:PRK01156   420 DISSKVSSLNQRIRALRENLDELSRNMEMLNgqsvCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIE-IEVKDIDEK 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  635 IERLKKRLQQLEvvEGDLMKTEDEYDQLEQKfrteqdkanflSQQLEEIKHQMAKHKaiekgeavsqEAELRHrfrlEEA 714
Cdd:PRK01156   499 IVDLKKRKEYLE--SEEINKSINEYNKIESA-----------RADLEDIKIKINELK----------DKHDKY----EEI 551

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1937928886  715 KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDysVLQQRFMEEETKNKNM 764
Cdd:PRK01156   552 KNRYKSLKLEDLDSKRTSWLNALAVISLIDIE--TNRSRSNEIKKQLNDL 599
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 287-787 5.04e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.12  E-value: 5.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  287 KSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIA 366
Cdd:TIGR00618  188 KKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  367 KGEcGNSSLMAEVESLRKR------VLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEA 440
Cdd:TIGR00618  268 RIE-ELRAQEAVLEETQERinrarkAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  441 FSRSKSECTQLHLNLEKEKNltkdllnelevvksrVKELECSESRLEKAELSLKDDLTKLKSFTVMLvderKNMMEKIKQ 520
Cdd:TIGR00618  347 LQTLHSQEIHIRDAHEVATS---------------IREISCQQHTLTQHIHTLQQQKTTLTQKLQSL----CKELDILQR 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  521 EERKVDGLNKNFKVEQGKVMdVTEKLIEESKKLLKLKSEMEEKVYSL--------------TKERDELMGKLRSEEERSC 586
Cdd:TIGR00618  408 EQATIDTRTSAFRDLQGQLA-HAKKQQELQQRYAELCAAAITCTAQCeklekihlqesaqsLKEREQQLQTKEQIHLQET 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  587 ELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPEDNKIRELTLEiERLKKRLQQLEVVEGDLMKTEDEYDQLEQKF 666
Cdd:TIGR00618  487 RKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGE-QTYAQLETSEEDVYHQLTSERKQRASLKEQM 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  667 RTEQDKANFLSQQLEEIKHQMAKHKAIEKGEAVSQEAELRHRFRLEEAKSRDLQA--EVQALKEKIHELMNKEDQLSQLQ 744
Cdd:TIGR00618  566 QEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKlqPEQDLQDVRLHLQQCSQELALKL 645

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1937928886  745 VDYSVLQQRFMEEETknknmgREVLNLTKELELSKRYSRALRP 787
Cdd:TIGR00618  646 TALHALQLTLTQERV------REHALSIRVLPKELLASRQLAL 682
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 290-444 5.16e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.15  E-value: 5.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  290 EDRQKLLKLEvDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEetnKSLQKAEEELQELREKIAK-- 367
Cdd:COG1579      4 EDLRALLDLQ-ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLE---KEIKRLELEIEEVEARIKKye 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  368 ---GECGNS----SLMAEVESLRKRVL-----------EMEGKDEEITKTEAQCRELKKKLQEEEhhsKELRLEVEKLQK 429
Cdd:COG1579     80 eqlGNVRNNkeyeALQKEIESLKRRISdledeilelmeRIEELEEELAELEAELAELEAELEEKK---AELDEELAELEA 156

                          170
                   ....*....|....*
gi 1937928886  430 RMSELEKLEEAFSRS 444
Cdd:COG1579    157 ELEELEAEREELAAK 171
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 204-769 8.50e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 8.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  204 EQERERLKKLLEQEK----AYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQ--------MHIEQLGLQSQKvQDLT 271
Cdd:pfam01576  326 EQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQalesenaeLQAELRTLQQAK-QDSE 404

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  272 QKLREEEEKLKAVTYKSKE-DRQKL--------LKLEVD--------FEHKASRFSQEHEEMNAKLAN-QESHNRQLRLK 333
Cdd:pfam01576  405 HKRKKLEGQLQELQARLSEsERQRAelaeklskLQSELEsvssllneAEGKNIKLSKDVSSLESQLQDtQELLQEETRQK 484

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  334 LvGLSQRIEELEETNKSLQKAEEELQELREKIAKgecgnsslmaEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQee 413
Cdd:pfam01576  485 L-NLSTRLRQLEDERNSLQEQLEEEEEAKRNVER----------QLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ-- 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  414 ehhsKELRLEVEKLQKRMSELEKLEEAFSRSKSECT----------QLHLNLEKEKNLTKDLLNELEVVKSRVKElecse 483
Cdd:pfam01576  552 ----RELEALTQQLEEKAAAYDKLEKTKNRLQQELDdllvdldhqrQLVSNLEKKQKKFDQMLAEEKAISARYAE----- 622

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  484 sRLEKAELSLKDDLTKLKSftvmLVDERKNMMEKIKQEERKvdglNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEK 563
Cdd:pfam01576  623 -ERDRAEAEAREKETRALS----LARALEEALEAKEELERT----NKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQ 693

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  564 VYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLdgieevEREINrGRSCKGSEFTCPEDNKIRELTLEIERLKKRLQ 643
Cdd:pfam01576  694 VEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQF------ERDLQ-ARDEQGEEKRRQLVKQVRELEAELEDERKQRA 766

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  644 QL----EVVEGDLMKTEDEYDQlEQKFRTEQDKanflsqQLEEIKHQMaKHKAIEKGEAVSQEAELRHRFRLEEAKSRDL 719
Cdd:pfam01576  767 QAvaakKKLELDLKELEAQIDA-ANKGREEAVK------QLKKLQAQM-KDLQRELEEARASRDEILAQSKESEKKLKNL 838

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 1937928886  720 QAEVQALKEkihELMNKEDQLSQLQVDYSVLQqrfmeEETKNKNMGREVL 769
Cdd:pfam01576  839 EAELLQLQE---DLAASERARRQAQQERDELA-----DEIASGASGKSAL 880
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 152-526 8.70e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 49.89  E-value: 8.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  152 RLEEKQKEtyRRMLEQLLLA-----EKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEK 226
Cdd:pfam07888   35 RLEECLQE--RAELLQAQEAanrqrEKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  227 enakrLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKL-LKLEVDfEHK 305
Cdd:pfam07888  113 -----LSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLqAKLQQT-EEE 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  306 ASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESL--- 382
Cdd:pfam07888  187 LRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMaaq 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  383 RKRVL-EMEGKDEEITKTEAQCRELKKKLQEEEHHSKELR--------LEVEKLQKRMSELEKLEEAFSRSKSECTQLHL 453
Cdd:pfam07888  267 RDRTQaELHQARLQAAQLTLQLADASLALREGRARWAQERetlqqsaeADKDRIEKLSAELQRLEERLQEERMEREKLEV 346

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1937928886  454 NLEKEKNLtkdllnelevvkSRVkelECSESRLEKAElsLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD 526
Cdd:pfam07888  347 ELGREKDC------------NRV---QLSESRRELQE--LKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
46 PHA02562
endonuclease subunit; Provisional
 201-416 1.14e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.63  E-value: 1.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  201 NLLEQERERLKKLLEQEKAyqarKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEK 280
Cdd:PHA02562   191 DHIQQQIKTYNKNIEEQRK----KNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAK 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  281 LKAvtykskeDRQKLLKLEVDFE--HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEEL 358
Cdd:PHA02562   267 IKS-------KIEQFQKVIKMYEkgGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKL 339

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1937928886  359 QELREKIAKGECGNSSLMAEVESLRKRVLEMEG----KDEEITKTEAQCRELKKKLQE---EEHH 416
Cdd:PHA02562   340 LELKNKISTNKQSLITLVDKAKKVKAAIEELQAefvdNAEELAKLQDELDKIVKTKSElvkEKYH 404
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
265-587 1.34e-05

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 48.37  E-value: 1.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  265 QKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLevdfEHKASRFSQEHEEMNAKLanqeshnRQLRLKlvgLSQRIEEL 344
Cdd:COG1340      1 SKTDELSSSLEELEEKIEELREEIEELKEKRDEL----NEELKELAEKRDELNAQV-------KELREE---AQELREKR 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  345 EETNKSLQKAEEELQELREKIakgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEV 424
Cdd:COG1340     67 DELNEKVKELKEERDELNEKL-------NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKELV 139

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  425 EKLQKRMSELEKLEEAfsrsksectqlhlnlEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFT 504
Cdd:COG1340    140 EKIKELEKELEKAKKA---------------LEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEA 204

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  505 VMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKvySLTKERDELMGKLRSEEER 584
Cdd:COG1340    205 DELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKE--ELEEKAEEIFEKLKKGEKL 282


                   ...
gi 1937928886  585 SCE 587
Cdd:COG1340    283 TTE 285
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 77-420 1.44e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.35  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   77 EDLIQLLSIMEGELQAREdvihmlRTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPIS-------- 148
Cdd:pfam17380  269 EFLNQLLHIVQHQKAVSE------RQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAiyaeqerm 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  149 ------ELDRL-EEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKsddftnllEQERERLKKLLEQEKAyq 221
Cdd:pfam17380  343 amererELERIrQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQ--------ELEAARKVKILEEERQ-- 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  222 aRKEKENAKRLNKLRDELVKLKSFAL-MLVDERQMHIEQLGLQSQKVQDLTQKLREEEEklkavtykskEDRQKLLKLEv 300
Cdd:pfam17380  413 -RKIQQQKVEMEQIRAEQEEARQREVrRLEEERAREMERVRLEEQERQQQVERLRQQEE----------ERKRKKLELE- 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  301 dfehKASRFSQEHEEMNAKLANQESHNRQlrlklvglsQRIEELEETNKSLQKAEEELQ-----ELREKIAKGECGNSSL 375
Cdd:pfam17380  481 ----KEKRDRKRAEEQRRKILEKELEERK---------QAMIEEERKRKLLEKEMEERQkaiyeEERRREAEEERRKQQE 547

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1937928886  376 MAEveslRKRVLE-MEGKDEEITKTEA--QCRELKKKLQEEEHHSKEL 420
Cdd:pfam17380  548 MEE----RRRIQEqMRKATEERSRLEAmeREREMMRQIVESEKARAEY 591
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 148-350 1.62e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  148 SELDRLEEKQKETyRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKE 227
Cdd:COG4942     27 AELEQLQQEIAEL-EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  228 NAKRLNKL---------------RDELVKLKSFALM--LVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKE 290
Cdd:COG4942    106 LAELLRALyrlgrqpplalllspEDFLDAVRRLQYLkyLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  291 DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKS 350
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 76-776 1.63e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.40  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   76 KEDLIQLLSIMEGELQAREDVIHMLRTEKTKPEV----LEAHYGSAE--------------------PEKVLRVLHRDAI 131
Cdd:pfam01576   70 KQELEEILHELESRLEEEEERSQQLQNEKKKMQQhiqdLEEQLDEEEaarqklqlekvtteakikklEEDILLLEDQNSK 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  132 LAQEKSIGEDVYEKPISELDRLEEKQKE------TYRRMLEQLLLAEKCHRRTVYELENEKHkhtdymnKSDDFTNLLEQ 205
Cdd:pfam01576  150 LSKERKLLEERISEFTSNLAEEEEKAKSlsklknKHEAMISDLEERLKKEEKGRQELEKAKR-------KLEGESTDLQE 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  206 ERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKlKSFALMLVDERQMHIEQLG-------LQSQKVQDLTQKLREEE 278
Cdd:pfam01576  223 QIAELQAQIAELRAQLAKKEEELQAALARLEEETAQ-KNNALKKIRELEAQISELQedleserAARNKAEKQRRDLGEEL 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  279 EKLKAV---TYKSKEDRQKLlklevdfehkasRFSQEHEEMNAKLANQE---SHNRQLRLKLVGLSQRIEELEETNKSLQ 352
Cdd:pfam01576  302 EALKTEledTLDTTAAQQEL------------RSKREQEVTELKKALEEetrSHEAQLQEMRQKHTQALEELTEQLEQAK 369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  353 KAEEELQELREKIakgECGNSSLMAEVESLRKRVLEMEGKDEeitKTEAQCRELKKKLQEEEHHSKELrleVEKLQKRMS 432
Cdd:pfam01576  370 RNKANLEKAKQAL---ESENAELQAELRTLQQAKQDSEHKRK---KLEGQLQELQARLSESERQRAEL---AEKLSKLQS 440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  433 ELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDllnelevvksrVKELECSESRlEKAELSlkddlTKLKSftvmLVDERK 512
Cdd:pfam01576  441 ELESVSSLLNEAEGKNIKLSKDVSSLESQLQD-----------TQELLQEETR-QKLNLS-----TRLRQ----LEDERN 499

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  513 NMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLlklkSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSV 592
Cdd:pfam01576  500 SLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTL----EALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTK 575

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  593 DLLKKRLDgieevereinrgrsckgsEFTCPEDNKiRELTLEIERLKKRLQQLEVVEGDL-MKTEDEYDQLEQKFRTEQD 671
Cdd:pfam01576  576 NRLQQELD------------------DLLVDLDHQ-RQLVSNLEKKQKKFDQMLAEEKAIsARYAEERDRAEAEAREKET 636

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  672 KANFLSQQLEE---IKHQMAKHKAIEKGE----AVSQEAELRHRFRLEEAKsRDLQAEVQALKEKIHELMNK----EDQL 740
Cdd:pfam01576  637 RALSLARALEEaleAKEELERTNKQLRAEmedlVSSKDDVGKNVHELERSK-RALEQQVEEMKTQLEELEDElqatEDAK 715

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1937928886  741 SQLQVDYSVLQQRFMEE--------ETKNKNMGREVLNLTKELE 776
Cdd:pfam01576  716 LRLEVNMQALKAQFERDlqardeqgEEKRRQLVKQVRELEAELE 759
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
290-441 2.59e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 48.32  E-value: 2.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  290 EDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQ----ESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKI 365
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQverlEAEVEELEAELEEKDERIERLERELSEARSEERREIRKDREI 467

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1937928886  366 akgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLqeeehHSKELR--LEVEKLQKrmSELEKLEEAF 441
Cdd:COG2433    468 -------SRLDREIERLERELEEERERIEELKRKLERLKELWKLE-----HSGELVpvKVVEKFTK--EAIRRLEEEY 531
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 181-783 2.72e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.50  E-value: 2.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  181 ELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEnaKRLNKLRDELVKLKSFALMLVDERQMHIEQL 260
Cdd:TIGR00606  232 QLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRK--KQMEKDNSELELKMEKVFQGTDEQLNDLYHN 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  261 glQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKlaNQESHNRQLRLKLVGLsqr 340
Cdd:TIGR00606  310 --HQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRAR--DSLIQSLATRLELDGF--- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  341 iEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLE------------MEGKDEEITKTEAQCRELKK 408
Cdd:TIGR00606  383 -ERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADeirdekkglgrtIELKKEILEKKQEELKFVIK 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  409 KLQEEEHHSKELRLEVEKLQKRMSELEKLEEafsRSKSECtqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEK 488
Cdd:TIGR00606  462 ELQQLEGSSDRILELDQELRKAERELSKAEK---NSLTET--LKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQ 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  489 AELSLKDDLT------KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 562
Cdd:TIGR00606  537 MEMLTKDKMDkdeqirKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELES 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  563 KVYSLTKERDELMGKLRSEEERScelscSVDLLKKRLDGIEEvEREINRGRSCKGSEFT----------CPEDNKIRELT 632
Cdd:TIGR00606  617 KEEQLSSYEDKLFDVCGSQDEES-----DLERLKEEIEKSSK-QRAMLAGATAVYSQFItqltdenqscCPVCQRVFQTE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  633 LEIERLKKRLQ--------QLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK---HKAIEKGEAVSQ 701
Cdd:TIGR00606  691 AELQEFISDLQsklrlapdKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKvnrDIQRLKNDIEEQ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  702 EAELrHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQL--QVDYSVLQQRFMEEETKNKNMGREVLNLTKELELSK 779
Cdd:TIGR00606  771 ETLL-GTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQaaKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNR 849


                   ....
gi 1937928886  780 RYSR 783
Cdd:TIGR00606  850 KLIQ 853
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 333-736 3.22e-05

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 47.93  E-value: 3.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  333 KLVGLSQRIEELEETNKS--LQKAEEELQELREKIAKGEcgnsslmAEVESLRKRVLEMEGKDE----EITKTEAQCREL 406
Cdd:pfam06160   61 SLPDIEELLFEAEELNDKyrFKKAKKALDEIEELLDDIE-------EDIKQILEELDELLESEEknreEVEELKDKYREL 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  407 KKKLQEEEHHSKELrleVEKLQKRMSELEKLEEAFSRSKSECtqlhlNLEKEKNLTKDLLNELEVVKSRVKELEcseSRL 486
Cdd:pfam06160  134 RKTLLANRFSYGPA---IDELEKQLAEIEEEFSQFEELTESG-----DYLEAREVLEKLEEETDALEELMEDIP---PLY 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  487 EKAELSLKDDLTKLKS-FTVMLVD----ERKNMMEKIKQEERKVDGLNKNFK------VEQG---------KVMDVTEKL 546
Cdd:pfam06160  203 EELKTELPDQLEELKEgYREMEEEgyalEHLNVDKEIQQLEEQLEENLALLEnleldeAEEAleeieeridQLYDLLEKE 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  547 IEESKKLLKLKSEMEEKVYSLTKERDELMGKLR----------SEEERSCELSCSVDLLKKRLDGIEEVEreinrgrsck 616
Cdd:pfam06160  283 VDAKKYVEKNLPEIEDYLEHAEEQNKELKEELErvqqsytlneNELERVRGLEKQLEELEKRYDEIVERL---------- 352

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  617 gseftcpEDNKIRELTLEiERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKH------ 690
Cdd:pfam06160  353 -------EEKEVAYSELQ-EELEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLELREIKRLVEKSnlpglp 424

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1937928886  691 --------KAIEKGEAVSQEAElRHRFRLEE--AKSRDLQAEVQALKEKIHELMNK 736
Cdd:pfam06160  425 esyldyffDVSDEIEDLADELN-EVPLNMDEvnRLLDEAQDDVDTLYEKTEELIDN 479
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 311-727 3.23e-05

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 47.75  E-value: 3.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  311 QEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLEME 390
Cdd:pfam19220    3 QRNELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  391 GkdeEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKleeafsrsksectQLHLNLEKEKNLT---KDLLN 467
Cdd:pfam19220   83 G---ELEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALER-------------QLAAETEQNRALEeenKALRE 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  468 ELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSftvmLVDErknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLI 547
Cdd:pfam19220  147 EAQAAEKALQRAEGELATARERLALLEQENRRLQA----LSEE---QAAELAELTRRLAELETQLDATRARLRALEGQLA 219

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  548 EESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRgrsckgseftcpednK 627
Cdd:pfam19220  220 AEQAERERAEAQLEEAVEAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAER---------------R 284

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  628 IRELTLEIERLKKRlqqLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEikHQMAKHKAIEKGEAVS-QEAELR 706
Cdd:pfam19220  285 LKEASIERDTLERR---LAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAA--KDAALERAEERIASLSdRIAELT 359

                          410       420
                   ....*....|....*....|....*
gi 1937928886  707 HRFRLE----EAKSRDLQAEVQALK 727
Cdd:pfam19220  360 KRFEVEraalEQANRRLKEELQRER 384
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 263-490 3.25e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 3.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  263 QSQKVQDLTQKLREEEEKLKAVtyksKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIE 342
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  343 ELEetnKSLQKAEEELQE-LREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELR 421
Cdd:COG4942     94 ELR---AELEAQKEELAElLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1937928886  422 LEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELevvKSRVKELECSESRLEKAE 490
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL---QQEAEELEALIARLEAEA 236
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 297-674 3.32e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.43  E-value: 3.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  297 KLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKgecgnsslm 376
Cdd:pfam02463  155 RLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY--------- 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  377 aeVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLE 456
Cdd:pfam02463  226 --LLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  457 KEKNLTKDLLNELEVVKSRVKELecsESRLEKAELSLKDDLTKLKSftvmlVDERKNMMEKIKQEERKVDGLNKNfkvEQ 536
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKA---EKELKKEKEEIEELEKELKE-----LEIKREAEEEEEEELEKLQEKLEQ---LE 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  537 GKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSvdllKKRLDGIEEVEREINRGRSCK 616
Cdd:pfam02463  373 EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKE----ELEILEEEEESIELKQGKLTE 448

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1937928886  617 GSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKAN 674
Cdd:pfam02463  449 EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR 506
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 205-464 3.76e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 48.10  E-value: 3.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  205 QERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLksfaLMLVDERQMHIEQLGLQSQ--KVQDLT-QKLREEEEKL 281
Cdd:pfam05667  243 RKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAEL----LSSFSGSSTTDTGLTKGSRftHTEKLQfTNEAPAATSS 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  282 KAVTYKSKEDRQKLLKLEVD-FEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQE 360
Cdd:pfam05667  319 PPTKVETEEELQQQREEELEeLQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLPD 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  361 LREKIAKgecgnssLMAEVESLRKRVLEMEGKDEEITKTE-AQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEklEE 439
Cdd:pfam05667  399 AEENIAK-------LQALVDASAQRLVELAGQWEKHRVPLiEEYRALKEAKSNKEDESQRKLEEIKELREKIKEVA--EE 469

                          250       260
                   ....*....|....*....|....*.
gi 1937928886  440 AfsRSKSEctqLHLNLEKE-KNLTKD 464
Cdd:pfam05667  470 A--KQKEE---LYKQLVAEyERLPKD 490
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 351-526 4.30e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.46  E-value: 4.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  351 LQKAEEELQELREKIAKgecgnssLMAEVESLRKrvlEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR 430
Cdd:COG1579     12 LQELDSELDRLEHRLKE-------LPAELAELED---ELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  431 MSELEKLEEAFSRSKsECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecsESRLEKAELSLKDDLTKLKSFTVMLVDE 510
Cdd:COG1579     82 LGNVRNNKEYEALQK-EIESLKRRISDLEDEILELMERIEELEEELAEL---EAELAELEAELEEKKAELDEELAELEAE 157

                          170
                   ....*....|....*.
gi 1937928886  511 RKNMMEKIKQEERKVD 526
Cdd:COG1579    158 LEELEAEREELAAKIP 173
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 373-604 4.73e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 4.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  373 SSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSRSKSEC 448
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaaLEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  449 TQLHLNLEKEKNLTKDLLNELEVVkSRVKELecsesrleKAELSLKDDLTKLKSFTVM--LVDERKNMMEKIKQEERKVD 526
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYRL-GRQPPL--------ALLLSPEDFLDAVRRLQYLkyLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1937928886  527 GLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEE 604
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
CortBP2 pfam09727
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ...
 394-512 5.13e-05

Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.


Pssm-ID: 462860 [Multi-domain]  Cd Length: 187  Bit Score: 45.29  E-value: 5.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  394 EEITKTEAQCRELKKKLQEeehhskeLRLEVEKLQKRMS---ELEKLEEAFSRSKSECTQLHLNLEKEKnltkdLLNELE 470
Cdd:pfam09727   80 AELEKLVEKQRETQRRMLE-------QLAAAEKRHRRVIrelEEEKRKHARDTAQGDDFTYLLEKERER-----LKQELE 147

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1937928886  471 VVKSRVKELEcseSRLEKAELSLKDDLTKLKSFTVMLVDERK 512
Cdd:pfam09727  148 QEKAQQKRLE---KELKKLLEKLEEELSKQKQIALLLVKERK 186
PLN02939 PLN02939
transferase, transferring glycosyl groups
 261-552 5.30e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 47.59  E-value: 5.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  261 GLQSQKVQDLTQKLREEEEK---LKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNA--KLANQE-SHNRQLRLKL 334
Cdd:PLN02939   124 QLSDFQLEDLVGMIQNAEKNillLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDAriKLAAQEkIHVEILEEQL 203

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  335 VGLSQRIEELEETNKSLQKA-EEELQELREKiakgecgNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEE 413
Cdd:PLN02939   204 EKLRNELLIRGATEGLCVHSlSKELDVLKEE-------NMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLREL 276

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  414 EHHSKELRLEVEKLQKR-----MSELEKLEEAFSRSKSECTQLHLNLEKEKnltkDLLNELEVVKSRVKELECSESRLEK 488
Cdd:PLN02939   277 ESKFIVAQEDVSKLSPLqydcwWEKVENLQDLLDRATNQVEKAALVLDQNQ----DLRDKVDKLEASLKEANVSKFSSYK 352

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1937928886  489 AELSLKddltKLKsftvmLVDERknmMEKIKQEERKVDGLNKNFKVEqgkVMDVTEKLIEESKK 552
Cdd:PLN02939   353 VELLQQ----KLK-----LLEER---LQASDHEIHSYIQLYQESIKE---FQDTLSKLKEESKK 401
PRK12704 PRK12704
phosphodiesterase; Provisional
 277-438 5.65e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 5.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  277 EEEKLKAVTYKskedRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQEshnRQLRLKLVGLSQRIEELEETNKSLQKAEE 356
Cdd:PRK12704    45 EEAKKEAEAIK----KEALLEAKEEIHKLRNEFEKELRERRNELQKLE---KRLLQKEENLDRKLELLEKREEELEKKEK 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  357 ELQELREKIAKgecgnssLMAEVESLRKRVLEmegKDEEI---TKTEAQcRELKKKLQEeehhskELRLEVEKLQKRMSE 433
Cdd:PRK12704   118 ELEQKQQELEK-------KEEELEELIEEQLQ---ELERIsglTAEEAK-EILLEKVEE------EARHEAAVLIKEIEE 180


                   ....*
gi 1937928886  434 LEKLE 438
Cdd:PRK12704   181 EAKEE 185
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
211-436 7.96e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 7.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  211 KKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDErqmHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKskE 290
Cdd:COG4717    296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPE---ELLELLDRIEELQELLREAEELEEELQLEELE--Q 370

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  291 DRQKLLKL-----EVDFEHKASRFSQEHE------EMNAKLANQESHNRQLrLKLVGLSQRIEELEETNKSLQKAEEELQ 359
Cdd:COG4717    371 EIAALLAEagvedEEELRAALEQAEEYQElkeeleELEEQLEELLGELEEL-LEALDEEELEEELEELEEELEELEEELE 449

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  360 ELREKIAKgecgnsslmaevesLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK 436
Cdd:COG4717    450 ELREELAE--------------LEAELEQLE-EDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511
46 PHA02562
endonuclease subunit; Provisional
 263-502 8.28e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.93  E-value: 8.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  263 QSQKVQDLTQKLREEEEKLKavTYKSKEDRQkllklevdfEHKASRFSQEHEEMNAKLANQESHNRQLrlklvgLSQRIE 342
Cdd:PHA02562   179 LNQQIQTLDMKIDHIQQQIK--TYNKNIEEQ---------RKKNGENIARKQNKYDELVEEAKTIKAE------IEELTD 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  343 ELEETNKSLQKAEEELQELREKIAKgecgnssLMAEVESLRKrVLEMEGKDEE-------ITKTEAQCRELKKKLQEEEH 415
Cdd:PHA02562   242 ELLNLVMDIEDPSAALNKLNTAAAK-------IKSKIEQFQK-VIKMYEKGGVcptctqqISEGPDRITKIKDKLKELQH 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  416 HSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDllnelevVKSRVKELEcSESRLEKAELS-LK 494
Cdd:PHA02562   314 SLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKK-------VKAAIEELQ-AEFVDNAEELAkLQ 385


                   ....*...
gi 1937928886  495 DDLTKLKS 502
Cdd:PHA02562   386 DELDKIVK 393
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 428-763 8.42e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.89  E-value: 8.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  428 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSL-KDDLTKLKSFTVM 506
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLnEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  507 LVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL------MGKLRS 580
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLkesekeKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  581 EEERSCELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYD 660
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  661 QLEQKFRTEQDKANFLSQQLEEIKHQMAKHKAIEKGEAVSQEAELRHRFRLEEAKSRDL-QAEVQALKEKIHELMNKEDQ 739
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELkKSEDLLKETQLVKLQEQLEL 488

                          330       340
                   ....*....|....*....|....
gi 1937928886  740 LSQLQVDYSVLQQRFMEEETKNKN 763
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVL 512
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 219-632 9.52e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 46.59  E-value: 9.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  219 AYQARKEKENAKRLNKLRDELvklksfalmlvderQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKS--KEDRQKLL 296
Cdd:pfam13166   85 FTLGEESIEIQEKIAKLKKEI--------------KDHEEKLDAAEANLQKLDKEKEKLEADFLDECWKKikRKKNSALS 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  297 KLEVDFEHKASRFSQEHEEMNAKLANQEShnrqlRLKLVGLSQRIEELEETNK-SLQKAEEELQELREKIAKGECGNS-- 373
Cdd:pfam13166  151 EALNGFKYEANFKSRLLREIEKDNFNAGV-----LLSDEDRKAALATVFSDNKpEIAPLTFNVIDFDALEKAEILIQKvi 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  374 SLMAEVESLRKR------VLEMEGKDEEITKTEAQC-----RELKKKLqeEEHHSKELRLEVEKLQKRMSELEKLEEAFS 442
Cdd:pfam13166  226 GKSSAIEELIKNpdladwVEQGLELHKAHLDTCPFCgqplpAERKAAL--EAHFDDEFTEFQNRLQKLIEKVESAISSLL 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  443 RSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecsESRLEK------AELSLKDDLTKLKSFTvmlvDERKNMME 516
Cdd:pfam13166  304 AQLPAVSDLASLLSAFELDVEDIESEAEVLNSQLDGL---RRALEAkrkdpfKSIELDSVDAKIESIN----DLVASINE 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  517 KIKQEERKVDGLNKnfKVEQGKV---MDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELScsvD 593
Cdd:pfam13166  377 LIAKHNEITDNFEE--EKNKAKKklrLHLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIKELE---A 451

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1937928886  594 LLKKRLDGIEEVEREINR-GRSckGSEFTCPEDNKIRELT 632
Cdd:pfam13166  452 QLRDHKPGADEINKLLKAfGFG--ELELSFNEEGKGYRII 489
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
264-480 1.04e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  264 SQKVQDLTQKLREEEEKLKAvtYKSKEDrqkllklEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEE 343
Cdd:COG3206    181 EEQLPELRKELEEAEAALEE--FRQKNG-------LVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  344 LEETNKSLQkAEEELQELREKIAKgecgnssLMAEVESLRKRVLE----MEGKDEEITKTEAQCR-ELKKKLQEEEHHSK 418
Cdd:COG3206    252 GPDALPELL-QSPVIQQLRAQLAE-------LEAELAELSARYTPnhpdVIALRAQIAALRAQLQqEAQRILASLEAELE 323

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1937928886  419 ELRLEVEKLQKRMSELEKLEEAFSRSKSEctqlHLNLEKEKNLTKDLLNELEvvkSRVKELE 480
Cdd:COG3206    324 ALQAREASLQAQLAQLEARLAELPELEAE----LRRLEREVEVARELYESLL---QRLEEAR 378
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
150-611 1.11e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  150 LDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFtNLLEQERERLKKllEQEKAYQARKEKENA 229
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEEL-EELEEELEELEA--ELEELREELEKLEKL 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  230 KRLNKLRDELVKLKSfalmlvdERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRF 309
Cdd:COG4717    125 LQLLPLYQELEALEA-------ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  310 SQEHEEMNAKLANQESHNRQLRlklvglsQRIEELEETNKSLQKaEEELQELREKIAKGE---------CGNSSLMAEVE 380
Cdd:COG4717    198 AEELEELQQRLAELEEELEEAQ-------EELEELEEELEQLEN-ELEAAALEERLKEARlllliaaalLALLGLGGSLL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  381 SLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRmsELEKLEEAFSRSKSECTQLHLNLEKEKN 460
Cdd:COG4717    270 SLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEE--ELEELLAALGLPPDLSPEELLELLDRIE 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  461 LTKDLLNELEvvkSRVKELECSESRLEKAELSLKDDLTKLKSFT--VMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGk 538
Cdd:COG4717    348 ELQELLREAE---ELEEELQLEELEQEIAALLAEAGVEDEEELRaaLEQAEEYQELKEELEELEEQLEELLGELEELLE- 423

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1937928886  539 vmDVTEKLIEEskKLLKLKSEMEEkvysLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDgIEEVEREINR 611
Cdd:COG4717    424 --ALDEEELEE--ELEELEEELEE----LEEELEELREELAELEAELEQLEEDGELAELLQE-LEELKAELRE 487
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
634-756 1.18e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  634 EIERLKKRLQQLEVvegdlmktedEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKhkaiekgEAVSQEAELRHRFRLEE 713
Cdd:COG3206    264 VIQQLRAQLAELEA----------ELAELSARYTPNHPDVIALRAQIAALRAQLQQ-------EAQRILASLEAELEALQ 326

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1937928886  714 AKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFME 756
Cdd:COG3206    327 AREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
507-746 1.24e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 45.29  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  507 LVDERKNMMEKIKQEERKVDGLN---KNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEE 583
Cdd:COG1340     13 LEEKIEELREEIEELKEKRDELNeelKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNELRE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  584 RSCELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPEdnKIRELTLEIERLKKRLQQLEvvegDLMKTEDEYDQLE 663
Cdd:COG1340     93 ELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPE--EEKELVEKIKELEKELEKAK----KALEKNEKLKELR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  664 QKFRTEQDKANFLSQQLEEIKHQMAKHKA-----IEKGEAVSQEA-ELRHRFRLEEAKSRDLQAEVQALKEKIHELMNKE 737
Cdd:COG1340    167 AELKELRKEAEEIHKKIKELAEEAQELHEemielYKEADELRKEAdELHKEIVEAQEKADELHEEIIELQKELRELRKEL 246


                   ....*....
gi 1937928886  738 DQLSQLQVD 746
Cdd:COG1340    247 KKLRKKQRA 255
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 337-736 1.28e-04

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 45.98  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  337 LSQRIEELEETNKS--LQKAEEELQELREKIAKGEcgnsslmAEVESLRKRVLEMEGKDE----EITKTEAQCRELKKKL 410
Cdd:PRK04778    84 IEEQLFEAEELNDKfrFRKAKHEINEIESLLDLIE-------EDIEQILEELQELLESEEknreEVEQLKDLYRELRKSL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  411 QEEEHHSKELrleVEKLQKRMSELEKLEEAFSRSKSE--CTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEcsesrlek 488
Cdd:PRK04778   157 LANRFSFGPA---LDELEKQLENLEEEFSQFVELTESgdYVEAREILDQLEEELAALEQIMEEIPELLKELQ-------- 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  489 aeLSLKDDLTKLKS-FTVMLVD----ERKNMMEKIKQEERKVDGLNKNfkVEQGKVMDVTEKLIEESKKLLKLKSEMEEK 563
Cdd:PRK04778   226 --TELPDQLQELKAgYRELVEEgyhlDHLDIEKEIQDLKEQIDENLAL--LEELDLDEAEEKNEEIQERIDQLYDILERE 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  564 V---YSLTKERDELMGKLRSEEERSCELSCSVDLLKKR-------LDGIEEVEREINRGRSckgseftcpEDNKIRELTL 633
Cdd:PRK04778   302 VkarKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSytlneseLESVRQLEKQLESLEK---------QYDEITERIA 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  634 E--------IERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKH-------KAIEKGEA 698
Cdd:PRK04778   373 EqeiayselQEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNKLHEIKRYLEKSnlpglpeDYLEMFFE 452

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1937928886  699 VSQE-----AEL-RHRFRLEE--AKSRDLQAEVQALKEKIHELMNK 736
Cdd:PRK04778   453 VSDEiealaEELeEKPINMEAvnRLLEEATEDVETLEEETEELVEN 498
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 458-786 1.57e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.08  E-value: 1.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  458 EKNLT--KDLLNELEvvkSRVKELEcSESrlEKAE--LSLKDDLTKLKSFtvMLVDERKNMMEKIKQEERKVDGLNKNFk 533
Cdd:COG1196    185 EENLErlEDILGELE---RQLEPLE-RQA--EKAEryRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAEL- 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  534 veqgkvmdvtEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERscelscsvdllkkrldgIEEVEREINRgr 613
Cdd:COG1196    256 ----------EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE-----------------LARLEQDIAR-- 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  614 sckgseftcpEDNKIRELTLEIERLKKRL-----------QQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 682
Cdd:COG1196    307 ----------LEERRRELEERLEELEEELaeleeeleeleEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  683 IKHQMAKHK------AIEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDysvLQQRFME 756
Cdd:COG1196    377 AEEELEELAeelleaLRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE---AAEEEAE 453

                          330       340       350
                   ....*....|....*....|....*....|
gi 1937928886  757 EETKNKNMGREVLNLTKELELSKRYSRALR 786
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELL 483
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 350-740 1.66e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.98  E-value: 1.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  350 SLQKAEEELQELrEKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEitKTEAQCRELKKKLQEEEHHS--KELRLEVEKL 427
Cdd:pfam12128  170 ALCDSESPLRHI-DKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPP--KSRLNRQQVEHWIRDIQAIAgiMKIRPEFTKL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  428 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVvKSRVKELECSESRLE-KAELSLKDDLTKLKSFTVM 506
Cdd:pfam12128  247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQ-LLRTLDDQWKEKRDElNGELSAADAAVAKDRSELE 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  507 LVDERKNMMEKIKQEERKVDglnknfkVEQGKVMDVTEKLIEESKKLLklksemEEKVYSLTKERDelmgklRSEEERSC 586
Cdd:pfam12128  326 ALEDQHGAFLDADIETAAAD-------QEQLPSWQSELENLEERLKAL------TGKHQDVTAKYN------RRRSKIKE 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  587 ELSCSVDLLKKRLDGIEEverEINRGRS-CKG------SEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEY 659
Cdd:pfam12128  387 QNNRDIAGIKDKLAKIRE---ARDRQLAvAEDdlqaleSELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  660 DQLEQ------KFRTEQDKAN--FLSQQLEEIKHQMAKHKAIEKGEAVSQeaelrhrfRLEEAKSRDLQAEVQ--ALKEK 729
Cdd:pfam12128  464 LQLENfderieRAREEQEAANaeVERLQSELRQARKRRDQASEALRQASR--------RLEERQSALDELELQlfPQAGT 535

                          410
                   ....*....|.
gi 1937928886  730 IHELMNKEDQL 740
Cdd:pfam12128  536 LLHFLRKEAPD 546
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 354-587 1.68e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  354 AEEELQELREKIakgecgnSSLMAEVESLRKRVLEMegkDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSE 433
Cdd:COG3883     14 ADPQIQAKQKEL-------SELQAELEAAQAELDAL---QAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  434 LEKLEEAFSRSKSEctqlhlnlekeknlTKDLLNELEVVKSrvkelecSEsrlekaelSLKDDLTKLKSFTvMLVDERKN 513
Cdd:COG3883     84 RREELGERARALYR--------------SGGSVSYLDVLLG-------SE--------SFSDFLDRLSALS-KIADADAD 133

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1937928886  514 MMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCE 587
Cdd:COG3883    134 LLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAA 207
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 197-477 1.82e-04

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 45.62  E-value: 1.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  197 DDFTNLLEQERERLKKLLEQEKAYQARKEKENAKR-------------LNKLRDELVKLKSF--------ALMLVDERQM 255
Cdd:pfam06160  107 EELDELLESEEKNREEVEELKDKYRELRKTLLANRfsygpaidelekqLAEIEEEFSQFEELtesgdyleAREVLEKLEE 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  256 HIEQLGLQSQKV----QDLTQKLREEEEKLKAvTYkskedrQKLLKLEVDFEHKAsrFSQEHEEMNAKLANQESHNRQLR 331
Cdd:pfam06160  187 ETDALEELMEDIpplyEELKTELPDQLEELKE-GY------REMEEEGYALEHLN--VDKEIQQLEEQLEENLALLENLE 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  332 LK-----LVGLSQRIEEL----EETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKR-------VLEMEGKDEE 395
Cdd:pfam06160  258 LDeaeeaLEEIEERIDQLydllEKEVDAKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSytlneneLERVRGLEKQ 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  396 ITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSectqlhlNLEKEKNLTKDLLNELEVVKSR 475
Cdd:pfam06160  338 LEELEKRYDEIVERLEEKEVAYSELQEELEEILEQLEEIEEEQEEFKESLQ-------SLRKDELEAREKLDEFKLELRE 410


                   ..
gi 1937928886  476 VK 477
Cdd:pfam06160  411 IK 412
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
544-786 2.00e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 44.90  E-value: 2.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  544 EKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINrgrsckgseftcp 623
Cdd:COG1340     18 EELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELN------------- 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  624 edNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQ----------DKANFLSQQLEEIKHQMAKHKAI 693
Cdd:COG1340     85 --EKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVlspeeekelvEKIKELEKELEKAKKALEKNEKL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  694 EkgEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLS----QLQVDYSVLQQRFMEEETKNKNMGREVL 769
Cdd:COG1340    163 K--ELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRkeadELHKEIVEAQEKADELHEEIIELQKELR 240

                          250
                   ....*....|....*..
gi 1937928886  770 NLTKELELSKRYSRALR 786
Cdd:COG1340    241 ELRKELKKLRKKQRALK 257
COG5022 COG5022
Myosin heavy chain [General function prediction only];
426-745 2.17e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.84  E-value: 2.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  426 KLQKRMSELEKLEEAFSRsKSECTQLHLNLEKEKNLtkdllNELEVVKSRVKelecSESRLEKAELSLKddltKLKSFtv 505
Cdd:COG5022    798 KLQPLLSLLGSRKEYRSY-LACIIKLQKTIKREKKL-----RETEEVEFSLK----AEVLIQKFGRSLK----AKKRF-- 861

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  506 mLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEME----EKVYSLTKERDEL---MGKL 578
Cdd:COG5022    862 -SLLKKETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSsdliENLEFKTELIARLkklLNNI 940

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  579 RSEEERSCELScsvdlLKKRLDGIEEVEREINRgrsckgsefTCPE-DNKIRELTLEIERLKKRLQQLEVVEGDLMKTED 657
Cdd:COG5022    941 DLEEGPSIEYV-----KLPELNKLHEVESKLKE---------TSEEyEDLLKKSTILVREGNKANSELKNFKKELAELSK 1006

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  658 EYDQLEQKfrteqdkanflSQQLEEIKHQMAKHKAIEK-----GEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHE 732
Cdd:COG5022   1007 QYGALQES-----------TKQLKELPVEVAELQSASKiisseSTELSILKPLQKLKGLLLLENNQLQARYKALKLRREN 1075

                          330
                   ....*....|...
gi 1937928886  733 LMNKEDQLSQLQV 745
Cdd:COG5022   1076 SLLDDKQLYQLES 1088
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 404-681 2.23e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 45.30  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  404 RELKKKLQEEEHHskELRLEVEKLQKRMSELEKLEEAFSRSKSEctQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 483
Cdd:PRK05771    34 EDLKEELSNERLR--KLRSLLTKLSEALDKLRSYLPKLNPLREE--KKKVSVKSLEELIKDVEEELEKIEKEIKELEEEI 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  484 SRL--EKAEL-SLKDDLTKLKSFTVMLVDERKNmmekikqeerkvdglnKNFKVEQGKV-MDVTE--KLIEESKKLLKLK 557
Cdd:PRK05771   110 SELenEIKELeQEIERLEPWGNFDLDLSLLLGF----------------KYVSVFVGTVpEDKLEelKLESDVENVEYIS 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  558 SEMEEKVYSLTKERdELMGKLRSEEERscelscsVDLLKKRLDGIEEVEREINRgrsckgseftcpEDNKIRELTLEIER 637
Cdd:PRK05771   174 TDKGYVYVVVVVLK-ELSDEVEEELKK-------LGFERLELEEEGTPSELIRE------------IKEELEEIEKERES 233

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1937928886  638 LKKRLQQLEVVEGDLMKTEDEYdqLEQkfrtEQDKANFLSQQLE 681
Cdd:PRK05771   234 LLEELKELAKKYLEELLALYEY--LEI----ELERAEALSKFLK 271
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 331-595 2.66e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 45.30  E-value: 2.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  331 RLKLVGLSQRIEELeetnkslqkaeeeLQELREkiakgecgnSSLMaEVESLRKrvlemEGKDEEITKTEAQCRELKKKL 410
Cdd:PRK05771     8 KVLIVTLKSYKDEV-------------LEALHE---------LGVV-HIEDLKE-----ELSNERLRKLRSLLTKLSEAL 59

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  411 QEEEHHSKELRLEVEKLQKRmsELEKLEEAFSRSKSEctqlHLNLEKEknlTKDLLNELEVVKSRVKELECSESRLEK-- 488
Cdd:PRK05771    60 DKLRSYLPKLNPLREEKKKV--SVKSLEELIKDVEEE----LEKIEKE---IKELEEEISELENEIKELEQEIERLEPwg 130

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  489 ---AELSLKDDLTKLKSFTVML----VDERKNMMEKIKQEERKVDGLN--------KNFKVEQGKVM---DVTEKLIEES 550
Cdd:PRK05771   131 nfdLDLSLLLGFKYVSVFVGTVpedkLEELKLESDVENVEYISTDKGYvyvvvvvlKELSDEVEEELkklGFERLELEEE 210

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1937928886  551 KKLLKLKSEMEEKVYSLTKERDELMGKLRS-EEERSCELSCSVDLL 595
Cdd:PRK05771   211 GTPSELIREIKEELEEIEKERESLLEELKElAKKYLEELLALYEYL 256
PRK12704 PRK12704
phosphodiesterase; Provisional
 338-491 3.30e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 3.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  338 SQRIEELEETNKS-LQKAEEELQELREKIakgecgnsslmaeveslrkrvlEMEGKDEEITKTEAQCRELKKKLQEEEHH 416
Cdd:PRK12704    30 EAKIKEAEEEAKRiLEEAKKEAEAIKKEA----------------------LLEAKEEIHKLRNEFEKELRERRNELQKL 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  417 SKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEK----NLTKDLLNELEVV--------KSRV-KELEcSE 483
Cdd:PRK12704    88 EKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEeeleELIEEQLQELERIsgltaeeaKEILlEKVE-EE 166


                   ....*...
gi 1937928886  484 SRLEKAEL 491
Cdd:PRK12704   167 ARHEAAVL 174
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
58-480 4.46e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 4.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   58 LKPSGESEKKTKKSVELSKEDLIQLLSImEGELQAREDVIHMLRTEKtkpEVLEAHYGSAEPE-KVLRVLHRDAILAQEK 136
Cdd:COG4717     59 FKPQGRKPELNLKELKELEEELKEAEEK-EEEYAELQEELEELEEEL---EELEAELEELREElEKLEKLLQLLPLYQEL 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  137 SIGEDVYEKPISELDRLEEKQKEtYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKS-DDFTNLLEQERERLKKLLE 215
Cdd:COG4717    135 EALEAELAELPERLEELEERLEE-LRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEE 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  216 QEKAYQARKE------------KENAKRLNKLRDELVKLKSFALMLVDERQMHIeqLGLQSQKVQDLTQKLREEEEKLKA 283
Cdd:COG4717    214 ELEEAQEELEeleeeleqleneLEAAALEERLKEARLLLLIAAALLALLGLGGS--LLSLILTIAGVLFLVLGLLALLFL 291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  284 VTYKSKEDRQKLLKlevDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRE 363
Cdd:COG4717    292 LLAREKASLGKEAE---ELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEL 368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  364 KIAKGECGNSSLMAEVESLRKRVLEMEGKDE---EITKTEAQCRELKKKLQE--EEHHSKELRLEVEKLQKRMSELEKLE 438
Cdd:COG4717    369 EQEIAALLAEAGVEDEEELRAALEQAEEYQElkeELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEELEEEL 448

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1937928886  439 EAFSRSKSECTQLHLNLEKEKNLTkDLLNELEVVKSRVKELE 480
Cdd:COG4717    449 EELREELAELEAELEQLEEDGELA-ELLQELEELKAELRELA 489
PLN02939 PLN02939
transferase, transferring glycosyl groups
 407-643 4.93e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.51  E-value: 4.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  407 KKKLQEEEHHSKELRlEVEKLQKRMSELE-KLEEAFSRSK---SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 482
Cdd:PLN02939   149 QARLQALEDLEKILT-EKEALQGKINILEmRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  483 ESRLEKAELSLKDDLTKLKSftvmlvderknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 562
Cdd:PLN02939   228 LDVLKEENMLLKDDIQFLKA-----------ELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYD 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  563 KVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRgrsckgSEFTCpedNKIRELTLEIERLKKRL 642
Cdd:PLN02939   297 CWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANV------SKFSS---YKVELLQQKLKLLEERL 367


                   .
gi 1937928886  643 Q 643
Cdd:PLN02939   368 Q 368
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 341-588 4.95e-04

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 43.65  E-value: 4.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  341 IEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHHSKEL 420
Cdd:pfam15905   86 VQERGEQDKRLQALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLELT-RVNELLKAKFSEDGTQKKMSSLSMELMKL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  421 RLEVEKLQKRMS--------ELEKLEEAFSRSKSECTQLH---LNLEKEKNLTKDLLNELEvvkSRVKELECSESRLEKA 489
Cdd:pfam15905  165 RNKLEAKMKEVMakqegmegKLQVTQKNLEHSKGKVAQLEeklVSTEKEKIEEKSETEKLL---EYITELSCVSEQVEKY 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  490 ELslkdDLTKLKSftvmLVDERKNMMEKIKQE-ERKVDGLNKnfkveQGKVMDVTEKLIEESKKllKLKSEMEEKVYSLT 568
Cdd:pfam15905  242 KL----DIAQLEE----LLKEKNDEIESLKQSlEEKEQELSK-----QIKDLNEKCKLLESEKE--ELLREYEEKEQTLN 306

                          250       260
                   ....*....|....*....|
gi 1937928886  569 KERDELMGKLRSEEERSCEL 588
Cdd:pfam15905  307 AELEELKEKLTLEEQEHQKL 326
46 PHA02562
endonuclease subunit; Provisional
 516-741 5.12e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 5.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  516 EKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL---MGKLRSEEERscelscsv 592
Cdd:PHA02562   195 QQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPsaaLNKLNTAAAK-------- 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  593 dlLKKRLDGIEEVEREINRGRSCKgsefTC-----PEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFR 667
Cdd:PHA02562   267 --IKSKIEQFQKVIKMYEKGGVCP----TCtqqisEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLL 340

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1937928886  668 TEQDKanfLSQQLEEIKHQMAKHKAIEKgeaVSQEAELRHRFRLEEAKSrdLQAEVQALKEKIHELMNKEDQLS 741
Cdd:PHA02562   341 ELKNK---ISTNKQSLITLVDKAKKVKA---AIEELQAEFVDNAEELAK--LQDELDKIVKTKSELVKEKYHRG 406
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 188-366 5.18e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 44.41  E-value: 5.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  188 KHTDYMNKSDDFTN---LLEQErERLKKLLEQE--------------------KAYQARKEKENAKRLNKLRDELVKLKS 244
Cdd:PRK10246   466 MRQRYKEKTQQLADvktICEQE-ARIKDLEAQRaqlqagqpcplcgstshpavEAYQALEPGVNQSRLDALEKEVKKLGE 544

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  245 FALMLVDErqmhIEQLGLQSQKVQDLTQKLREEEEKLK----------AVTYKSKEDRQKLLKLEVDFEHKASRFSQEHE 314
Cdd:PRK10246   545 EGAALRGQ----LDALTKQLQRDESEAQSLRQEEQALTqqwqavcaslNITLQPQDDIQPWLDAQEEHERQLRLLSQRHE 620

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1937928886  315 eMNAKLANQESHNRQLR-------------LKLVGLSQRIEELEET--------NKSLQKAEEELQELREKIA 366
Cdd:PRK10246   621 -LQGQIAAHNQQIIQYQqqieqrqqqlltaLAGYALTLPQEDEEASwlatrqqeAQSWQQRQNELTALQNRIQ 692
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 393-610 5.42e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.43  E-value: 5.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  393 DEEITKTEAQCRELKKKLQEEEhhskELRLEVEKLQKRMSE-LEKLEEAFSRSKSEctqlhlnLEKE-KNLTKDLLNELE 470
Cdd:PRK00409   519 NELIASLEELERELEQKAEEAE----ALLKEAEKLKEELEEkKEKLQEEEDKLLEE-------AEKEaQQAIKEAKKEAD 587

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  471 VVKSRVKELECSESRLEKAELsLKDDLTKLKsftvmlvdERKNMMEKIKQEERKVdglNKNFKV----------EQGKVM 540
Cdd:PRK00409   588 EIIKELRQLQKGGYASVKAHE-LIEARKRLN--------KANEKKEKKKKKQKEK---QEELKVgdevkylslgQKGEVL 655

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937928886  541 DVTEK--LIEESkKLLKLK---SEMEekvySLTKERDELMGKLRSEEERSCELSCSVDLLKKRL-DGIEEVEREIN 610
Cdd:PRK00409   656 SIPDDkeAIVQA-GIMKMKvplSDLE----KIQKPKKKKKKKPKTVKPKPRTVSLELDLRGMRYeEALERLDKYLD 726
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 534-786 5.64e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 5.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  534 VEQGKVMDVTE-------KLIEESKKLLKLKSEMEE-------------KVYSLTKERDELMGKLR------------SE 581
Cdd:TIGR02168  141 IEQGKISEIIEakpeerrAIFEEAAGISKYKERRKEterklertrenldRLEDILNELERQLKSLErqaekaerykelKA 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  582 EERSCELSCSVDLLKKRLDGIEEVEREINrgrsckgseftcpednkirELTLEIERLKKRLQQLEvveGDLMKTEDEYDQ 661
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELK-------------------EAEEELEELTAELQELE---EKLEELRLEVSE 278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  662 LEQKFRTEQDKANFLSQQLEEIKHQMAKHKAiEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIhelmnkedqlS 741
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRE-RLANLERQLEELEAQLEELESKLDELAEELAELEEKL----------E 347

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1937928886  742 QLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE-LSKRYSRALR 786
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESRLEELEEQLEtLRSKVAQLEL 393
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
203-411 6.85e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 6.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  203 LEQERERLKKLLEQ-EKAYQARKEKEN-----------AKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDL 270
Cdd:COG3206    180 LEEQLPELRKELEEaEAALEEFRQKNGlvdlseeakllLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  271 TQKLREEEeklkavtykskeDRQKLLKLEVDFEHKASRFSQEHEEMnaklanqeshnRQLRLKLVGLSQRIEEleETNKS 350
Cdd:COG3206    260 LQSPVIQQ------------LRAQLAELEAELAELSARYTPNHPDV-----------IALRAQIAALRAQLQQ--EAQRI 314

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1937928886  351 LQKAEEELQELRekiakgecgnsslmAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQ 411
Cdd:COG3206    315 LASLEAELEALQ--------------AREASLQAQLAQLEARLAELPELEAELRRLEREVE 361
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 954-1166 6.97e-04

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 43.76  E-value: 6.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  954 IPSPNVMSQKPKSAD-------------PTLGPERAMSPVTITTISREKSPeggRSAFAD--RPASPIQIMTVSTSAAPT 1018
Cdd:PLN03209   323 IPSQRVPPKESDAADgpkpvptkpvtpeAPSPPIEEEPPQPKAVVPRPLSP---YTAYEDlkPPTSPIPTPPSSSPASSK 399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1019 E---IAVSPESQEVPMGRTILKVtPEKQTVPAPVRKYNSNANIITTEDNKIhihlgsqfKRSPGPAAE-GVSPVITVRPV 1094
Cdd:PLN03209   400 SvdaVAKPAEPDVVPSPGSASNV-PEVEPAQVEAKKTRPLSPYARYEDLKP--------PTSPSPTAPtGVSPSVSSTSS 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886 1095 nVTAEKEVSTGTV-----------------------LRSPRNHLSSRPGASKVTSTITITPVTTSSTRGTQSVSGQDGSS 1151
Cdd:PLN03209   471 -VPAVPDTAPATAatdaaapppanmrplspyavyddLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQ 549

                          250
                   ....*....|....*.
gi 1937928886 1152 QRPTP-TRIPMSKGMK 1166
Cdd:PLN03209   550 PKPRPlSPYTMYEDLK 565
ADIP pfam11559
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ...
 424-528 8.45e-04

Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.


Pssm-ID: 463295 [Multi-domain]  Cd Length: 151  Bit Score: 41.15  E-value: 8.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  424 VEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSf 503
Cdd:pfam11559   44 LQQRDRDLEFRESLNETIRTLEAEIERLQSKIERLKTQLEDLERELALLQAKERQLEKKLKTLEQKLKNEKEELQRLKN- 122

                           90       100
                   ....*....|....*....|....*
gi 1937928886  504 tvMLVDERKNMMEKIKQEERKVDGL 528
Cdd:pfam11559  123 --ALQQIKTQFAHEVKKRDREIEKL 145
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
400-688 1.02e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  400 EAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEE-AFSRSKSECTQLHL-NLEKEKNLTKDLLNELEVVKSRVK 477
Cdd:COG4913    616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEySWDEIDVASAEREIaELEAELERLDASSDDLAALEEQLE 695

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  478 ELECSESRLEKAELSLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLNKNFKVEQgkvmdvtEKLIEESKKLLKLK 557
Cdd:COG4913    696 ELEAELEELEEELDELKGEIGRLEK-------ELEQAEEELDELQDRLEAAEDLARLEL-------RALLEERFAAALGD 761

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  558 SEMEEKVYSLTKERDELMGKLRSEEERscelscsvdllkkrldgIEEVEREINRgrsckgsEFTCPednkIRELTLEIER 637
Cdd:COG4913    762 AVERELRENLEERIDALRARLNRAEEE-----------------LERAMRAFNR-------EWPAE----TADLDADLES 813

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1937928886  638 L---KKRLQQLEvvEGDLMKTEDEYDQLEQKFrTEQDKANFLS---QQLEEIKHQMA 688
Cdd:COG4913    814 LpeyLALLDRLE--EDGLPEYEERFKELLNEN-SIEFVADLLSklrRAIREIKERID 867
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
544-752 1.19e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  544 EKLIEESKKLLKLKSEmeeKVYSLTKERDELMGKLRSEEERscelscsVDLLKKRLDGIEEVEREINRGRsckgseftcp 623
Cdd:COG4717     49 ERLEKEADELFKPQGR---KPELNLKELKELEEELKEAEEK-------EEEYAELQEELEELEEELEELE---------- 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  624 edNKIRELTLEIERLKKRLQ------QLEVVEGDLMKTEDEYDQLEQKFRTEQDKAN---FLSQQLEEIKHQMAKHKAIE 694
Cdd:COG4717    109 --AELEELREELEKLEKLLQllplyqELEALEAELAELPERLEELEERLEELRELEEeleELEAELAELQEELEELLEQL 186

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1937928886  695 KGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQ 752
Cdd:COG4717    187 SLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEER 244
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 336-504 1.21e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.31  E-value: 1.21e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   336 GLSQRIEELEETNKSLQKAEEELQELREKIAKGecgNSSLMAEVESLRKRVLEMEGKDEEITKteaqcrELKKKLQEEEH 415
Cdd:smart00787  148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDR---KDALEEELRQLKQLEDELEDCDPTELD------RAKEKLKKLLQ 218

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   416 HSKELRLEVEKLQKRMSELEKleeafsrsksectqlhlNLEKEKNLTKDLLNELEVVKSRVKELE-CSESRLEKaelsLK 494
Cdd:smart00787  219 EIMIKVKKLEELEEELQELES-----------------KIEDLTNKKSELNTEIAEAEKKLEQCRgFTFKEIEK----LK 277

                           170
                    ....*....|
gi 1937928886   495 DDLTKLKSFT 504
Cdd:smart00787  278 EQLKLLQSLT 287
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 463-780 1.24e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  463 KDLLNELEVVKsrvKELECSESRLEKAELSLKDDLTKLKSFTV---MLVDERKNMMEKIKQEERKVDGLNKN---FKVEQ 536
Cdd:TIGR04523   36 KQLEKKLKTIK---NELKNKEKELKNLDKNLNKDEEKINNSNNkikILEQQIKDLNDKLKKNKDKINKLNSDlskINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  537 GKVMDVTEKLIEESKKLLKLKSEMEEKVY-------SLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREI 609
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKKENKKNIDkflteikKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKI 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  610 NRGRSCKGSEFTCPE--DNKIRELTLEIERLKKRLQQLEvveGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQM 687
Cdd:TIGR04523  193 KNKLLKLELLLSNLKkkIQKNKSLESQISELKKQNNQLK---DNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  688 ---------AKHKAIEKGEAVSQ-EAELRH-RFRLEEAKSRDLQAEVQALKEKIHELMNK----EDQLSQLQVDYSVLQQ 752
Cdd:TIGR04523  270 sekqkeleqNNKKIKELEKQLNQlKSEISDlNNQKEQDWNKELKSELKNQEKKLEEIQNQisqnNKIISQLNEQISQLKK 349

                          330       340
                   ....*....|....*....|....*...
gi 1937928886  753 RFMEEETKNKNMGREVLNLTKELELSKR 780
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKK 377
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 294-875 1.75e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 1.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  294 KLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGEcgns 373
Cdd:TIGR00606  169 KALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYE---- 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  374 slmAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKL----QKRMSELEKLEEAFSRSKSE-- 447
Cdd:TIGR00606  245 ---NELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVfqgtDEQLNDLYHNHQRTVREKERel 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  448 --CTQLHLNLEKEKNLTKDLLNELEVVKSRVK---ELECSESR---LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 519
Cdd:TIGR00606  322 vdCQRELEKLNKERRLLNQEKTELLVEQGRLQlqaDRHQEHIRardSLIQSLATRLELDGFERGPFSERQIKNFHTLVIE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  520 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEErsceLSCSVDLLKKRL 599
Cdd:TIGR00606  402 RQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQ----LEGSSDRILELD 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  600 DGIEEVEREINRGRSCKGSEFTCPEDNKIRELTLEIERLKKRLQQ--------LEVVEGDLMKTEDEYDQLEQKFRTEQD 671
Cdd:TIGR00606  478 QELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQemeqlnhhTTTRTQMEMLTKDKMDKDEQIRKIKSR 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  672 KANFLSQQLEEIKHQMAKHKAIEKgeavsqeaeLRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSvlQ 751
Cdd:TIGR00606  558 HSDELTSLLGYFPNKKQLEDWLHS---------KSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE--D 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  752 QRF-----MEEETKNKNMGREVLNLTKELEL----SKRYSRALRPSGNGRRMVdVPVASTGVQTEAVCGDAAEEETPAVF 822
Cdd:TIGR00606  627 KLFdvcgsQDEESDLERLKEEIEKSSKQRAMlagaTAVYSQFITQLTDENQSC-CPVCQRVFQTEAELQEFISDLQSKLR 705

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1937928886  823 IRKSFQEEnhimsnLRQVGLKKPMERSSVLDRYPPAANELTMRKSWIPWMRKR 875
Cdd:TIGR00606  706 LAPDKLKS------TESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNK 752
mukB PRK04863
chromosome partition protein MukB;
72-413 1.83e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   72 VELSKE--DLIQLLSIMEGELQA--------REDVIHMLRTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEK-SIGE 140
Cdd:PRK04863   310 VEMARElaELNEAESDLEQDYQAasdhlnlvQTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARaEAAE 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  141 DVYEKPISEL----DRLEEKQKET--YRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERL---K 211
Cdd:PRK04863   390 EEVDELKSQLadyqQALDVQQTRAiqYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLsvaQ 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  212 KLLEQ-EKAYQA-RK-----EKENAKrlNKLRDELVKLKSFalmlvderQMHIEQLGLQSQKVQDLTQKLREEEEKLKAV 284
Cdd:PRK04863   470 AAHSQfEQAYQLvRKiagevSRSEAW--DVARELLRRLREQ--------RHLAEQLQQLRMRLSELEQRLRQQQRAERLL 539

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  285 TYKSKEDRQKLLKlEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREK 364
Cdd:PRK04863   540 AEFCKRLGKNLDD-EDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQ 618

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1937928886  365 IakGECGNSSlmAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEE 413
Cdd:PRK04863   619 S--GEEFEDS--QDVTEYMQQLLERE---RELTVERDELAARKQALDEE 660
mukB PRK04863
chromosome partition protein MukB;
204-500 1.99e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  204 EQERERLKKLL---------EQEKAYQARKEK---ENAKRLNKLRDelvklksFALMLVDERqmhIEQLGLQSQkvqDLT 271
Cdd:PRK04863   389 EEEVDELKSQLadyqqaldvQQTRAIQYQQAVqalERAKQLCGLPD-------LTADNAEDW---LEEFQAKEQ---EAT 455

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  272 QKLREEEEKLkAVTYKSKEDRQKLLKLEVDFEHKASRfSQEHEEMNAKLANQESHnRQLRLKLVGLSQRIEELEETNKSL 351
Cdd:PRK04863   456 EELLSLEQKL-SVAQAAHSQFEQAYQLVRKIAGEVSR-SEAWDVARELLRRLREQ-RHLAEQLQQLRMRLSELEQRLRQQ 532

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  352 QKAEEELQELREKIAKGEcgnsSLMAEVESLRkrvlemEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRM 431
Cdd:PRK04863   533 QRAERLLAEFCKRLGKNL----DDEDELEQLQ------EELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARA 602

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1937928886  432 SELEKLEEAFSRSkseCTQLHLNLEKEKNLTKDLLNELEvvksRVKELECSESRLEKAELSLKDDLTKL 500
Cdd:PRK04863   603 PAWLAAQDALARL---REQSGEEFEDSQDVTEYMQQLLE----RERELTVERDELAARKQALDEEIERL 664
mukB PRK04863
chromosome partition protein MukB;
274-612 2.22e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 2.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  274 LREEEEKLKAVTYKSKEDRQKLLKLEVDFehkaSRFSQEHEEMnAKLANQESHNRQLRLKLVGLSQRIEELEETNKS--- 350
Cdd:PRK04863   791 LRAEREELAERYATLSFDVQKLQRLHQAF----SRFIGSHLAV-AFEADPEAELRQLNRRRVELERALADHESQEQQqrs 865

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  351 -LQKAEEELQELREKIakgecGNSSLMAEvESLRKRVLEMEgkdEEITKTE----------AQCRELKK---KLQEEEHH 416
Cdd:PRK04863   866 qLEQAKEGLSALNRLL-----PRLNLLAD-ETLADRVEEIR---EQLDEAEeakrfvqqhgNALAQLEPivsVLQSDPEQ 936

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  417 SKELRLEVEKLQKRMSELEK----LEEAFSRsksectQLHLNLEKEKN-LTKDL-LNELEVVKSRVKELECSESRLE--- 487
Cdd:PRK04863   937 FEQLKQDYQQAQQTQRDAKQqafaLTEVVQR------RAHFSYEDAAEmLAKNSdLNEKLRQRLEQAEQERTRAREQlrq 1010

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  488 -KAELSLKDD-LTKLKS-FTVM--LVDERKNMMEKI---------KQEERKVDGLNKNFKVEQGKvmdvteklieeskkl 553
Cdd:PRK04863  1011 aQAQLAQYNQvLASLKSsYDAKrqMLQELKQELQDLgvpadsgaeERARARRDELHARLSANRSR--------------- 1075

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1937928886  554 lklKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKK------RLDGIEEVEREINRG 612
Cdd:PRK04863  1076 ---RNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAgwcavlRLVKDNGVERRLHRR 1137
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
203-447 2.34e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 41.43  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  203 LEQERERLKKLLEQ--EKAYQARKE-KENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQK---LRE 276
Cdd:COG1340     13 LEEKIEELREEIEElkEKRDELNEElKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKlneLRE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  277 EEEKLKAVTYKSKEDRQKLLKLEVDFEHKasRFSQEHEEMNAKlanqesHNRQLRLKLVGLSQRIEELE---ETNKSLQK 353
Cdd:COG1340     93 ELDELRKELAELNKAGGSIDKLRKEIERL--EWRQQTEVLSPE------EEKELVEKIKELEKELEKAKkalEKNEKLKE 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  354 AEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITK----TEAQCRELKKKLQEEEHHSKELRLEVEKLQK 429
Cdd:COG1340    165 LRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKeadeLHKEIVEAQEKADELHEEIIELQKELRELRK 244

                          250
                   ....*....|....*...
gi 1937928886  430 RMSELEKLEEAFSRSKSE 447
Cdd:COG1340    245 ELKKLRKKQRALKREKEK 262
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 252-413 2.63e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 2.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  252 ERQMHIEQLGLQSQKVQDLTQKLREE---EEKLKAVTYKSKEDRQKllklEVDFEHKASRFSQEHEEMNAKLANQESHNR 328
Cdd:COG3096    506 SQQALAQRLQQLRAQLAELEQRLRQQqnaERLLEEFCQRIGQQLDA----AEELEELLAELEAQLEELEEQAAEAVEQRS 581

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  329 QLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIakGECGNSSlmAEVESLRKRVLEMEgkdEEITKTEAQCRELKK 408
Cdd:COG3096    582 ELRQQLEQLRARIKELAARAPAWLAAQDALERLREQS--GEALADS--QEVTAAMQQLLERE---REATVERDELAARKQ 654


                   ....*
gi 1937928886  409 KLQEE 413
Cdd:COG3096    655 ALESQ 659
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 383-587 2.67e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 2.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  383 RKRVLEmEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLT 462
Cdd:pfam17380  358 RKRELE-RIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQRE 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  463 KDLLNElevvkSRVKELEcsesRLEKAELSLKDDLTKLKSftvMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDV 542
Cdd:pfam17380  437 VRRLEE-----ERAREME----RVRLEEQERQQQVERLRQ---QEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEER 504

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1937928886  543 TEKLIEESKKLLKLKSEMEEKVYSLTKERDelmgKLRSEEERSCE 587
Cdd:pfam17380  505 KQAMIEEERKRKLLEKEMEERQKAIYEEER----RREAEEERRKQ 545
HAP1_N pfam04849
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ...
 225-364 3.29e-03

HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.


Pssm-ID: 461455 [Multi-domain]  Cd Length: 309  Bit Score: 41.16  E-value: 3.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  225 EKENakrlNKLRDELVKLKSFALMLVDERQMHI----EQLGLQSQKVQDLTQKLREEEEKLKavtyKSKEDRQKLLKLEV 300
Cdd:pfam04849  177 EEEN----LKLRSEASHLKTETDTYEEKEQQLMsdcvEQLSEANQQMAELSEELARKMEENL----RQQEEITSLLAQIV 248

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1937928886  301 DFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEEtnkSLQKAEEELQELREK 364
Cdd:pfam04849  249 DLQHKCKELGIENEELQQHLQASKEAQRQLTSELQELQDRYAECLG---MLHEAQEELKELRKK 309
PRK00106 PRK00106
ribonuclease Y;
295-478 3.45e-03

ribonuclease Y;


Pssm-ID: 178867 [Multi-domain]  Cd Length: 535  Bit Score: 41.39  E-value: 3.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  295 LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRI-EELEETNKSLQK-----AEEELQELREKIAKG 368
Cdd:PRK00106    12 LIGLVIGYVLISIKMKSAKEAAELTLLNAEQEAVNLRGKAERDAEHIkKTAKRESKALKKellleAKEEARKYREEIEQE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  369 ECGNSSLMAEVES-LRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRmsELEKLEEAFSRSKSE 447
Cdd:PRK00106    92 FKSERQELKQIESrLTERATSLDRKDENLSSKEKTLESKEQSLTDKSKHIDEREEQVEKLEEQ--KKAELERVAALSQAE 169

                          170       180       190
                   ....*....|....*....|....*....|.
gi 1937928886  448 CTQLHLnLEKEKNLTKDLLNELEVVKSRVKE 478
Cdd:PRK00106   170 AREIIL-AETENKLTHEIATRIREAEREVKD 199
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
628-786 3.82e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 3.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  628 IRELTLE-------IERLKKRLQQLEVVEGDLMKTEDEYDQLEQkfrteqdkanfLSQQLEEIKHQMAKHKAIEKGEAVS 700
Cdd:COG4913    213 VREYMLEepdtfeaADALVEHFDDLERAHEALEDAREQIELLEP-----------IRELAERYAAARERLAELEYLRAAL 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  701 QEAELRHRFRLEEAKSRDLQAEVQALKEKIHELmnkEDQLSQLQVDYSVLQQRFMEEETKNKN-MGREVLNLTKELE--- 776
Cdd:COG4913    282 RLWFAQRRLELLEAELEELRAELARLEAELERL---EARLDALREELDELEAQIRGNGGDRLEqLEREIERLERELEere 358

                          170
                   ....*....|.
gi 1937928886  777 -LSKRYSRALR 786
Cdd:COG4913    359 rRRARLEALLA 369
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 362-727 4.02e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.63  E-value: 4.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  362 REKIAKGECGNSSLMAEVESlrKRVLEMEGKDEEITKTEAQCRELKKKLQEEehhskelRLEVEKLQKRMSELEKLEEAF 441
Cdd:pfam05483   62 QEGLKDSDFENSEGLSRLYS--KLYKEAEKIKKWKVSIEAELKQKENKLQEN-------RKIIEAQRKAIQELQFENEKV 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  442 SRSKSECTQLHLNLEKEKNLTKDLLNELEVV------KSRVKELECSESRLEKAEL--SLKDDLTKLKSFTVMLVDERKN 513
Cdd:pfam05483  133 SLKLEEEIQENKDLIKENNATRHLCNLLKETcarsaeKTKKYEYEREETRQVYMDLnnNIEKMILAFEELRVQAENARLE 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  514 MMEKIKQEERKVDGLNKNFKVEQGK--------VMDVTEK---------LIEESK-------KLLKLKSE----MEEKVY 565
Cdd:pfam05483  213 MHFKLKEDHEKIQHLEEEYKKEINDkekqvsllLIQITEKenkmkdltfLLEESRdkanqleEKTKLQDEnlkeLIEKKD 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  566 SLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVE----REINRGRSCKG---SEFTCPEDNKIRELTLEIERL 638
Cdd:pfam05483  293 HLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKeaqmEELNKAKAAHSfvvTEFEATTCSLEELLRTEQQRL 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  639 KKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKAIEK--GEAVSQEAELRHRFRLEEAKS 716
Cdd:pfam05483  373 EKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKiaEELKGKEQELIFLLQAREKEI 452

                          410
                   ....*....|.
gi 1937928886  717 RDLQAEVQALK 727
Cdd:pfam05483  453 HDLEIQLTAIK 463
PRK09039 PRK09039
peptidoglycan -binding protein;
337-480 4.29e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.72  E-value: 4.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  337 LSQRI----EELEETNKslqkaeeELQELREKIAKGECGNSSLMAEVESLRKRVLEME-----------GKDEEITKTEA 401
Cdd:PRK09039    44 LSREIsgkdSALDRLNS-------QIAELADLLSLERQGNQDLQDSVANLRASLSAAEaersrlqallaELAGAGAAAEG 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  402 QCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSRSKSEctqlhlnlEKEKNLT-KDLLNELEV-VKSR 475
Cdd:PRK09039   117 RAGELAQELDSEKQVSARALAQVELLNQQIAALRRqlaaLEAALDASEKR--------DRESQAKiADLGRRLNVaLAQR 188


                   ....*
gi 1937928886  476 VKELE 480
Cdd:PRK09039   189 VQELN 193
PRK12704 PRK12704
phosphodiesterase; Provisional
 361-523 4.58e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.92  E-value: 4.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  361 LREKIAKgecgnsSLMAEVESLRKRVLEMEGKDEEITKTEAQC---RELKKKLQEEEHHSKELRLEVEKLQKRmseLEKL 437
Cdd:PRK12704    24 VRKKIAE------AKIKEAEEEAKRILEEAKKEAEAIKKEALLeakEEIHKLRNEFEKELRERRNELQKLEKR---LLQK 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  438 EEAFSRsKSEctqlhlNLEKEKNltkDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTvmlVDERKNM-ME 516
Cdd:PRK12704    95 EENLDR-KLE------LLEKREE---ELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLT---AEEAKEIlLE 161


                   ....*..
gi 1937928886  517 KIKQEER 523
Cdd:PRK12704   162 KVEEEAR 168
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 33-742 4.62e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 41.35  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   33 SEDAKKNKANRKEEDVMASgTIKRHLKPSGESEKKTKKSVELSKEdliqllsimegELQAREDVIHMLRTEKTKPEVL-E 111
Cdd:pfam10174   38 SPELKKERALRKEEAARIS-VLKEQYRVTQEENQHLQLTIQALQD-----------ELRAQRDLNQLLQQDFTTSPVDgE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  112 AHYGSAEP-EKVLRVLHRDailaQEKSIGE-DVYEKPISELDRLEEKQKETY-------RRMLEqlLLAEKCHRRTVYEL 182
Cdd:pfam10174  106 DKFSTPELtEENFRRLQSE----HERQAKElFLLRKTLEEMELRIETQKQTLgardesiKKLLE--MLQSKGLPKKSGEE 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  183 ENEKHKHT-DYMNKSDDFTNLLEQ-ERERLKKLLEQEKAYQARKEKENAKRLNKLRD-ELVKLKSFalmlvdERQMHIEQ 259
Cdd:pfam10174  180 DWERTRRIaEAEMQLGHLEVLLDQkEKENIHLREELHRRNQLQPDPAKTKALQTVIEmKDTKISSL------ERNIRDLE 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  260 LGLQSQKVQDL--TQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAkLANQESHNRQ----LRLK 333
Cdd:pfam10174  254 DEVQMLKTNGLlhTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLET-LTNQNSDCKQhievLKES 332

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  334 LVGLSQRIE-----------ELEETNKSLQKAEEELQELREKIA--KGECGNSSLMAEVESLRKRVLE--MEGKDEEITK 398
Cdd:pfam10174  333 LTAKEQRAAilqtevdalrlRLEEKESFLNKKTKQLQDLTEEKStlAGEIRDLKDMLDVKERKINVLQkkIENLQEQLRD 412

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  399 TEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKS-ECTQLHLNLEKEKNLTKDLLNELEVVKSRVK 477
Cdd:pfam10174  413 KDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQRErEDRERLEELESLKKENKDLKEKVSALQPELT 492

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  478 ELECSESRLEKAELSLKDDLTKLKSFTvmlvderKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKlIEESKKLLKLK 557
Cdd:pfam10174  493 EKESSLIDLKEHASSLASSGLKKDSKL-------KSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTN-PEINDRIRLLE 564

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  558 SEMEEKVYSLTK---ERDELMGKLR-SEEERSC------EL-SCSVDLLK---KRLDGIEEVEREINRGRSCKGSEFTCP 623
Cdd:pfam10174  565 QEVARYKEESGKaqaEVERLLGILReVENEKNDkdkkiaELeSLTLRQMKeqnKKVANIKHGQQEMKKKGAQLLEEARRR 644

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  624 EDNKIReltleierlKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHkaIEKGEAVSQEA 703
Cdd:pfam10174  645 EDNLAD---------NSQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQ--LEEILEMKQEA 713

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1937928886  704 ELR---------HRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQ 742
Cdd:pfam10174  714 LLAaisekdaniALLELSSSKKKKTQEEVMALKREKDRLVHQLKQQTQ 761
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 229-734 4.79e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.10  E-value: 4.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  229 AKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASR 308
Cdd:COG5185    106 LIKLPNYEWSADILISLLYLYKSEIVALKDELIKVEKLDEIADIEASYGEVETGIIKDIFGKLTQELNQNLKKLEIFGLT 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  309 FSQEHEEMNAKLANQEshnrqlrlKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLE 388
Cdd:COG5185    186 LGLLKGISELKKAEPS--------GTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEK 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  389 MEGKDEEI-TKTEAQCRELKKKLQEEehhSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHlNLEKEKNLTKDLLN 467
Cdd:COG5185    258 LVEQNTDLrLEKLGENAESSKRLNEN---ANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA-AAEAEQELEESKRE 333

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  468 ELEVVKSRVKELECSESRLEKAELSLKDDLTKLksFTVMLVDERKNMMEKIKQEerkvdgLNKNFKVEQGKVMDVTEKLI 547
Cdd:COG5185    334 TETGIQNLTAEIEQGQESLTENLEAIKEEIENI--VGEVELSKSSEELDSFKDT------IESTKESLDEIPQNQRGYAQ 405

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  548 EESKKLLKLKSEMEEkvysltkERDELMGKLRSEEErscELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTcpeDNK 627
Cdd:COG5185    406 EILATLEDTLKAADR-------QIEELQRQIEQATS---SNEEVSKLLNELISELNKVMREADEESQSRLEEAY---DEI 472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  628 IRELTLEIERLKKRLQQLE---------------VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKA 692
Cdd:COG5185    473 NRSVRSKKEDLNEELTQIEsrvstlkatleklraKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQ 552

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1937928886  693 IEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHELM 734
Cdd:COG5185    553 ASNAKTDGQAANLRTAVIDELTQYLSTIESQQAREDPIPDQA 594
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 627-784 4.87e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 4.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  627 KIRELTLEIERLKKRLQQLE----VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKH-KAIEKGEAVSQ 701
Cdd:COG4942     42 ELAALKKEEKALLKQLAALErriaALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlRALYRLGRQPP 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  702 EA---------ELRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLT 772
Cdd:COG4942    122 LAlllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLL 201

                          170
                   ....*....|..
gi 1937928886  773 KELELSKRYSRA 784
Cdd:COG4942    202 ARLEKELAELAA 213
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
627-776 5.36e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 5.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  627 KIRELTLEIERLKKRLQQLevvEGDLMKTEDEYDQLEQKFRT-EQDKANFLSQQLEEIKHQMAKHKAiEKGEAVSQEAEL 705
Cdd:COG4913    289 RLELLEAELEELRAELARL---EAELERLEARLDALREELDElEAQIRGNGGDRLEQLEREIERLER-ELEERERRRARL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  706 RHRFR---LEEAKSRD----LQAEVQALKEKIHELMNK--------EDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLN 770
Cdd:COG4913    365 EALLAalgLPLPASAEefaaLRAEAAALLEALEEELEAleealaeaEAALRDLRRELRELEAEIASLERRKSNIPARLLA 444


                   ....*.
gi 1937928886  771 LTKELE 776
Cdd:COG4913    445 LRDALA 450
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 533-747 5.92e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 40.68  E-value: 5.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  533 KVEQGKVMDVTEKLIEESKKLLKLKSEMEEKvySLTKERDELMGKLRSEEerscelscsvdLLKKRLDGIEEVEREINRg 612
Cdd:PRK05771    39 ELSNERLRKLRSLLTKLSEALDKLRSYLPKL--NPLREEKKKVSVKSLEE-----------LIKDVEEELEKIEKEIKE- 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  613 rsckgseftcpEDNKIRELTLEIERLKKRLQQLEVVEG-DL-MKTEDEYDQLEQKFRT------EQDKANFLSQQLEEIK 684
Cdd:PRK05771   105 -----------LEEEISELENEIKELEQEIERLEPWGNfDLdLSLLLGFKYVSVFVGTvpedklEELKLESDVENVEYIS 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  685 HQMAKHKAI---EKGEAVSQEAELR-HRFR-------------LEEAKSR--DLQAEVQALKEKIHELMNKEDQLSQLQV 745
Cdd:PRK05771   174 TDKGYVYVVvvvLKELSDEVEEELKkLGFErleleeegtpselIREIKEEleEIEKERESLLEELKELAKKYLEELLALY 253


                   ..
gi 1937928886  746 DY 747
Cdd:PRK05771   254 EY 255
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 453-786 6.23e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 6.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  453 LNLEK-EKNLTK--DLLNELEvvksrvKELECSESRLEKAE--LSLKDDLTKL-KSFTVMLVDERKNMMEKIKQEERKVD 526
Cdd:TIGR02168  179 RKLERtRENLDRleDILNELE------RQLKSLERQAEKAEryKELKAELRELeLALLVLRLEELREELEELQEELKEAE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  527 GLNKNFKVEqgkvMDVTEKLIEESKKLlklKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRldgIEEVE 606
Cdd:TIGR02168  253 EELEELTAE----LQELEEKLEELRLE---VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ---LEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  607 REINRGRSckgseftcpednKIRELTLEIERLKKRLQQLEVV----EGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 682
Cdd:TIGR02168  323 AQLEELES------------KLDELAEELAELEEKLEELKEEleslEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  683 IKHQMAKHKAiekgeavsqeaelrhrfRLEEAKSR--DLQAEVQALKEKIHELMNK--EDQLSQLQVDYSVLQQRFMEEE 758
Cdd:TIGR02168  391 LELQIASLNN-----------------EIERLEARleRLEDRRERLQQEIEELLKKleEAELKELQAELEELEEELEELQ 453

                          330       340
                   ....*....|....*....|....*...
gi 1937928886  759 TKNKNMGREVLNLTKELELSKRYSRALR 786
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAE 481
DYN1 COG5245
Dynein, heavy chain [Cytoskeleton];
155-570 6.26e-03

Dynein, heavy chain [Cytoskeleton];


Pssm-ID: 227570 [Multi-domain]  Cd Length: 3164  Bit Score: 41.13  E-value: 6.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  155 EKQKETYRRMLEqllLAEKCHRRTVYELENEKHKhtdymNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNK 234
Cdd:COG5245   2102 RKYNEYGRGMGE---LKEQLSNTVVILGVKEKNA-----DDALSGTPGERLEREVKSVFVEAPRDMLFLLEEEVRKRKGS 2173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  235 LRdelvKLKSFALMLVDERQMHIEQL-GLQSQKVQDLTQK---LREEEEKLKAVTY---KSKEDRQKLLK---------- 297
Cdd:COG5245   2174 VM----KFKSSKKPAVLEAVLFVYKIkKASLREIRSFIRPpgdLCIEMEDVCDLLGfeaKIWFGEQQSLRrddfiriigk 2249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  298 --LEVDFEHKASRFsQEHEEMNAKLANQESHNRQLRL---------KLVGLSQRIEELEETNKSLQKAEEELQELREKIA 366
Cdd:COG5245   2250 ypDEIEFDLEARRF-REARECSDPSFTGSILNRASKAcgplkrwlvRECNRSKVLEVKIPLREEEKRIDGEAFLVEDRLT 2328

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  367 KGECGNSSLMAEVESLRKR----VLEMEGKdeeitktEAQCRELKKKLQEEEHHSKELRLEVEK-------LQKRMSELe 435
Cdd:COG5245   2329 LGKGLSSDLMTFKLRRRSYysldILRVHGK-------IADMDTVHKDVLRSIFVSEILINEDSEwggvfseVPKLMVEL- 2400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  436 kLEEAFSRSKSECTQLHLN-LEK--EKNLTKDLL-NELEVVKSRVKEL--ECSESRLEKAELSLKDDLT--------KLK 501
Cdd:COG5245   2401 -DGDGHPSSCLHPYIGTLGfLCRaiEFGMSFIRIsKEFRDKEIRRRQFitEGVQKIEDFKEEACSTDYGlensrirkDLQ 2479

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1937928886  502 SFTVMLVDERKNMMEKIKQ--EERKVDGLNKNfkvEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKE 570
Cdd:COG5245   2480 DLTAVLNDPSSKIVTSQRQmyDEKKAILGSFR---EMEFAFGLSQARREGSDKIIGDAEALDEEIGRLIKE 2547
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 625-723 6.28e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 40.84  E-value: 6.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  625 DNKIRELTLEIERLKK--------RLQQLEvveGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKAIEKG 696
Cdd:COG0542    417 ERRLEQLEIEKEALKKeqdeasfeRLAELR---DELAELEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKE 493

                           90       100
                   ....*....|....*....|....*..
gi 1937928886  697 EAVSQEAELRHRFRLEEAKSRDLQAEV 723
Cdd:COG0542    494 LAELEEELAELAPLLREEVTEEDIAEV 520
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
599-779 6.47e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 6.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  599 LDGIEEVEREINRGRSckgseftcpEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKA----- 673
Cdd:COG4717     70 LKELKELEEELKEAEE---------KEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEaleae 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  674 -NFLSQQLEEIKHQMAKHK-AIEKGEAVSQEAElRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQ 751
Cdd:COG4717    141 lAELPERLEELEERLEELReLEEELEELEAELA-ELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170       180
                   ....*....|....*....|....*...
gi 1937928886  752 QRFMEEETKNKNMGREVLNLTKELELSK 779
Cdd:COG4717    220 EELEELEEELEQLENELEAAALEERLKE 247
COG0610 COG0610
Type I site-specific restriction-modification system, R (restriction) subunit and related ...
 207-427 6.49e-03

Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ... [Defense mechanisms];


Pssm-ID: 440375 [Multi-domain]  Cd Length: 936  Bit Score: 40.62  E-value: 6.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  207 RERLKKLLEQEKAYQARKEKEnaKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKlkaVTY 286
Cdd:COG0610    706 TEKLEALDEAVERFLGDEEAR--KEFKKLFKELSRLYNLLSPDDEFGDLELEKYRDDVSFYLALRAKLRKLGEK---LDL 780

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  287 KSKEDR-QKLLKLEVDFEHKASRfsqehEEMNAKLANQEShnrqlrlklvgLSQRIEEL-EETNK---SLQKAEEELQEL 361
Cdd:COG0610    781 KEYEEKiRQLLDEAIDLERKEIK-----PRIKQNPVQYRK-----------FSELLEEIiEEYNNgalDADEVLEELEEL 844

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1937928886  362 REKIAKGE--CGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKL 427
Cdd:COG0610    845 AKEVKEEEerAEEEGLNEEELAFYDALAENLGDEKLKELAKELDDLLKKNVTVDWRKRESVRAKLRDA 912
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
380-511 7.00e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 40.61  E-value: 7.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  380 ESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLE-------VEKLQKRMSELEKLEEAFSRSKSECTqlh 452
Cdd:COG2433    392 EEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEleekderIERLERELSEARSEERREIRKDREIS--- 468

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1937928886  453 lNLEKEknlTKDLLNELEVVKSRVKELECSESRLEKA-ELSLKDDLT---KLKSFT---VMLVDER 511
Cdd:COG2433    469 -RLDRE---IERLERELEEERERIEELKRKLERLKELwKLEHSGELVpvkVVEKFTkeaIRRLEEE 530
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 209-786 7.05e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 40.51  E-value: 7.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  209 RLKKLLEQEKAYQARKEKEnakrLNKLRDELVKLKSFAL---MLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVT 285
Cdd:pfam07111   56 EGSQALSQQAELISRQLQE----LRRLEEEVRLLRETSLqqkMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVR 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  286 YKSKEDRQK-LLKLEVDFEHKASRFSQEHEEMNAKLANqeshnrqlrlKLVGLSQRIEELEETN----KSLQKAEEELQE 360
Cdd:pfam07111  132 KNLEEGSQReLEEIQRLHQEQLSSLTQAHEEALSSLTS----------KAEGLEKSLNSLETKRageaKQLAEAQKEAEL 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  361 LREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKL--- 437
Cdd:pfam07111  202 LRKQLSKTQEELEAQVTLVESLRKYVGEQVPPEVHSQTWELERQELLDTMQHLQEDRADLQATVELLQVRVQSLTHMlal 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  438 -EEAFSRSKSECTQLHLNLEKEknlTKDLLNEL-EVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMM 515
Cdd:pfam07111  282 qEEELTRKIQPSDSLEPEFPKK---CRSLLNRWrEKVFALMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQ 358

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  516 EKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLL 595
Cdd:pfam07111  359 RALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARIPSLSNRL 438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  596 KKRLDGIEEVEREINRG--------RSCKGSEFTCPEDNkirELTLEIERLKK-------------RLQQLEV------V 648
Cdd:pfam07111  439 SYAVRKVHTIKGLMARKvalaqlrqESCPPPPPAPPVDA---DLSLELEQLREernrldaelqlsaHLIQQEVgrareqG 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  649 EGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHqmAKHKAIEkgEAVSQEAELRHRFRLEEAKSRDLQAEVQA-LK 727
Cdd:pfam07111  516 EAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQ--GQQESTE--EAASLRQELTQQQEIYGQALQEKVAEVETrLR 591

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1937928886  728 EKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKEL--ELSKRYSRALR 786
Cdd:pfam07111  592 EQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEArkEEGQRLARRVQ 652
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 62-427 7.79e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 40.72  E-value: 7.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886   62 GESEKKTKKSVELSKEDLIQLLSIMEGELQAREDVIHMLRtektKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGED 141
Cdd:TIGR00618  551 LTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQ----NITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  142 VYEKpiseldRLEEKQKETYrrmlEQLLLAEKchrrTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQ 221
Cdd:TIGR00618  627 LQDV------RLHLQQCSQE----LALKLTAL----HALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQL 692

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  222 ARKEKENAKRLNKLRDELVKLKSFalmlvdERQMHIEQLGLQSQKvqdltQKLREEEEKLKAVTYKSKEDRQKLLKLEVD 301
Cdd:TIGR00618  693 TYWKEMLAQCQTLLRELETHIEEY------DREFNEIENASSSLG-----SDLAAREDALNQSLKELMHQARTVLKARTE 761

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  302 FEHKASrfsqEHEEMNAKLANQESHNRQlrlklvGLSQRIEELEETNKSLQKAEEELQELR---EKIAKGECgnSSLMAE 378
Cdd:TIGR00618  762 AHFNNN----EEVTAALQTGAELSHLAA------EIQFFNRLREEDTHLLKTLEAEIGQEIpsdEDILNLQC--ETLVQE 829

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1937928886  379 VESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKL 427
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 206-447 9.65e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.11  E-value: 9.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  206 ERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKL---- 281
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMamer 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  282 -KAVTYKSKEDRQK-------------------LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQ-R 340
Cdd:pfam17380  347 eRELERIRQEERKRelerirqeeiameisrmreLERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQiR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937928886  341 IEELEETNKSLQKAEE----ELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCR--------ELKK 408
Cdd:pfam17380  427 AEQEEARQREVRRLEEerarEMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRkilekeleERKQ 506

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1937928886  409 KLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSE 447
Cdd:pfam17380  507 AMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQ 545
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH