|
Name |
Accession |
Description |
Interval |
E-value |
| KIND |
smart00750 |
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to ... |
37-217 |
2.96e-50 |
|
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to the C-terminal protein kinase catalytic fold (C lobe). Its presence at the N terminus of signalling proteins and the absence of the active-site residues in the catalytic and activation loops suggest that it folds independently and is likely to be non-catalytic. The occurrence of KIND only in metazoa implies that it has evolved from the catalytic protein kinase domain into an interaction domain possibly by keeping the substrate-binding features
:
Pssm-ID: 214801 Cd Length: 176 Bit Score: 176.05 E-value: 2.96e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 37 VSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQSLCITPDTLAFNtSGNVCFMEQLSDDPEGAFVPPEFDVTG 116
Cdd:smart00750 1 VSLADILEVRGRPLNEEEIWAVCLQCLGALRELHRQAKSGNILLTWDGLLKL-DGSVAFKTPEQSRPDPYFMAPEVIQGQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 117 N-TFEAHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEeklqLTSSCRVCRSlSAVG 195
Cdd:smart00750 80 SyTEKADIYSLGITLYEALDYELPYNEERELSAILEILLNGMPADDPRDRSNLEGVSAARS----FEDFMRLCAS-RLPQ 154
|
170 180
....*....|....*....|..
gi 116268127 196 RRVLSIESFGALQDVSESSWRE 217
Cdd:smart00750 155 RREAANHYLAHCRALFAETLEL 176
|
|
| PKc_like super family |
cl21453 |
Protein Kinases, catalytic domain; The protein kinase superfamily is mainly composed of the ... |
444-608 |
1.02e-45 |
|
Protein Kinases, catalytic domain; The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-specific and tyrosine-specific protein kinases. It also includes RIO kinases, which are atypical serine protein kinases, aminoglycoside phosphotransferases, and choline kinases. These proteins catalyze the transfer of the gamma-phosphoryl group from ATP to hydroxyl groups in specific substrates such as serine, threonine, or tyrosine residues of proteins.
The actual alignment was detected with superfamily member smart00750:
Pssm-ID: 473864 Cd Length: 176 Bit Score: 162.95 E-value: 1.02e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 444 VSLQDLLSQLGRPFREYELWALCLACLRALQTRP----EHPAYLCLDSVLVAeDGAVLFQPPPANGSyDSFFLAPELAEE 519
Cdd:smart00750 1 VSLADILEVRGRPLNEEEIWAVCLQCLGALRELHrqakSGNILLTWDGLLKL-DGSVAFKTPEQSRP-DPYFMAPEVIQG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 520 RLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMARRSAP---------ERPSAAEAIKVCGSYLLQRGMD 590
Cdd:smart00750 79 QSYTEKADIYSLGITLYEALDYELPYNEERELSAILEILLNGMPADDPRdrsnlegvsAARSFEDFMRLCASRLPQRREA 158
|
170
....*....|....*...
gi 116268127 591 SRKILAHLRASICQVYQE 608
Cdd:smart00750 159 ANHYLAHCRALFAETLEL 176
|
|
| RasGEF |
pfam00617 |
RasGEF domain; Guanine nucleotide exchange factor for Ras-like small GTPases. |
1475-1619 |
5.47e-24 |
|
RasGEF domain; Guanine nucleotide exchange factor for Ras-like small GTPases.
:
Pssm-ID: 459872 Cd Length: 179 Bit Score: 100.74 E-value: 5.47e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1475 QLTLLQQELFQKCHPVHFLNSRalgvmdkstaipkasssesLSAKTCSLFLPNyvqdkyLLQLLRNADDVSTWVAAEIVT 1554
Cdd:pfam00617 5 QLTLIEFELFRKIKPRELLGSA-------------------WSKKDKKENSPN------IEAMIARFNKLSNWVASEILS 59
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116268127 1555 SHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAVRQ-SPAWRILPAKIAEVMEELKAV 1619
Cdd:pfam00617 60 EEDLKKRAKVIKKFIKIAEHCRELNNFNSLMAILSGLNSSPISRlKKTWELVSKKYKKTLEELEKL 125
|
|
| REM |
cd06224 |
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also ... |
1254-1368 |
3.97e-18 |
|
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately N-terminal to the RasGef (Cdc25-like) domain. REM contacts the GTPase and is assumed to participate in the catalytic activity of the exchange factor. Proteins with the REM domain include Sos1 and Sos2, which relay signals from tyrosine-kinase mediated signalling to Ras, RasGRP1-4, RasGRF1,2, CNrasGEF, and RAP-specific nucleotide exchange factors, to name a few.
:
Pssm-ID: 100121 Cd Length: 122 Bit Score: 82.08 E-value: 3.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1254 TPLGLMAYLYSSDAFLE-GYVQQFLYTFRYFCTPHDFLHFLLDRIN---STLTRAHQDPTSTFTKIYRRSLCVLQAWVED 1329
Cdd:cd06224 1 TLEALIEHLTSTFDMPDpSFVSTFLLTYRSFTTPTELLEKLIERYEiapPENLEYNDWDKKKSKPIRLRVLNVLRTWVEN 80
|
90 100 110
....*....|....*....|....*....|....*....
gi 116268127 1330 CYaVDFPRNSGLLGKLEDFISSkILPLDGSAKHLLGLLE 1368
Cdd:cd06224 81 YP-YDFFDDEELLELLEEFLNR-LVQEGALLQELKKLLR 117
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
619-896 |
6.49e-08 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.03 E-value: 6.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 619 SVVELKPSVAPAPEPSPGFLPVNSdtglvAVPGPvPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQE 698
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVS-----ATPLP-PGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPP 2767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 699 ESEERGGQRegegeeklsleahAGSPSLKTPDGPVPGPGPQGAAPEPLGASvqrDSAQGRPCPPPQAPANQPEGASSAAP 778
Cdd:PHA03247 2768 APAPPAAPA-------------AGPPRRLTRPAVASLSESRESLPSPWDPA---DPPAAVLAPAAALPPAASPAGPLPPP 2831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 779 GSPVPAPPTKASAlPVEqgPAEPIPPGVASGG---LRPDALGPTTAHHGPRHPP-----KPPRSKATERPGQEPEGPGAT 850
Cdd:PHA03247 2832 TSAQPTAPPPPPG-PPP--PSLPLGGSVAPGGdvrRRPPSRSPAAKPAAPARPPvrrlaRPAVSRSTESFALPPDQPERP 2908
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 116268127 851 P----AGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEA 896
Cdd:PHA03247 2909 PqpqaPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGA 2958
|
|
| SPS1 super family |
cl43163 |
Serine/threonine protein kinase [Signal transduction mechanisms]; |
123-349 |
6.97e-05 |
|
Serine/threonine protein kinase [Signal transduction mechanisms];
The actual alignment was detected with superfamily member COG0515:
Pssm-ID: 440281 [Multi-domain] Cd Length: 482 Bit Score: 47.31 E-value: 6.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 123 IYSLGATLKAAL---------------------EYVAEPTLEPRLSQDLEALLSRMQAEDPGDRP-DLESIIALCEEKLQ 180
Cdd:COG0515 191 VYSLGVTLYELLtgrppfdgdspaellrahlrePPPPPSELRPDLPPALDAIVLRALAKDPEERYqSAAELAAALRAVLR 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 181 LTSSCRVCRSLSAVGRRVLSIESFGALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTK 260
Cdd:COG0515 271 SLAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAAAAAAAAALAAAAAAAAAAAAAA 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 261 ALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPD 340
Cdd:COG0515 351 LLAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAALAAAAAAAAAA 430
|
....*....
gi 116268127 341 PRKAFLDRK 349
Cdd:COG0515 431 AAAAAAAAA 439
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| KIND |
smart00750 |
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to ... |
37-217 |
2.96e-50 |
|
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to the C-terminal protein kinase catalytic fold (C lobe). Its presence at the N terminus of signalling proteins and the absence of the active-site residues in the catalytic and activation loops suggest that it folds independently and is likely to be non-catalytic. The occurrence of KIND only in metazoa implies that it has evolved from the catalytic protein kinase domain into an interaction domain possibly by keeping the substrate-binding features
Pssm-ID: 214801 Cd Length: 176 Bit Score: 176.05 E-value: 2.96e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 37 VSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQSLCITPDTLAFNtSGNVCFMEQLSDDPEGAFVPPEFDVTG 116
Cdd:smart00750 1 VSLADILEVRGRPLNEEEIWAVCLQCLGALRELHRQAKSGNILLTWDGLLKL-DGSVAFKTPEQSRPDPYFMAPEVIQGQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 117 N-TFEAHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEeklqLTSSCRVCRSlSAVG 195
Cdd:smart00750 80 SyTEKADIYSLGITLYEALDYELPYNEERELSAILEILLNGMPADDPRDRSNLEGVSAARS----FEDFMRLCAS-RLPQ 154
|
170 180
....*....|....*....|..
gi 116268127 196 RRVLSIESFGALQDVSESSWRE 217
Cdd:smart00750 155 RREAANHYLAHCRALFAETLEL 176
|
|
| KIND |
smart00750 |
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to ... |
444-608 |
1.02e-45 |
|
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to the C-terminal protein kinase catalytic fold (C lobe). Its presence at the N terminus of signalling proteins and the absence of the active-site residues in the catalytic and activation loops suggest that it folds independently and is likely to be non-catalytic. The occurrence of KIND only in metazoa implies that it has evolved from the catalytic protein kinase domain into an interaction domain possibly by keeping the substrate-binding features
Pssm-ID: 214801 Cd Length: 176 Bit Score: 162.95 E-value: 1.02e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 444 VSLQDLLSQLGRPFREYELWALCLACLRALQTRP----EHPAYLCLDSVLVAeDGAVLFQPPPANGSyDSFFLAPELAEE 519
Cdd:smart00750 1 VSLADILEVRGRPLNEEEIWAVCLQCLGALRELHrqakSGNILLTWDGLLKL-DGSVAFKTPEQSRP-DPYFMAPEVIQG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 520 RLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMARRSAP---------ERPSAAEAIKVCGSYLLQRGMD 590
Cdd:smart00750 79 QSYTEKADIYSLGITLYEALDYELPYNEERELSAILEILLNGMPADDPRdrsnlegvsAARSFEDFMRLCASRLPQRREA 158
|
170
....*....|....*...
gi 116268127 591 SRKILAHLRASICQVYQE 608
Cdd:smart00750 159 ANHYLAHCRALFAETLEL 176
|
|
| RasGEF |
pfam00617 |
RasGEF domain; Guanine nucleotide exchange factor for Ras-like small GTPases. |
1475-1619 |
5.47e-24 |
|
RasGEF domain; Guanine nucleotide exchange factor for Ras-like small GTPases.
Pssm-ID: 459872 Cd Length: 179 Bit Score: 100.74 E-value: 5.47e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1475 QLTLLQQELFQKCHPVHFLNSRalgvmdkstaipkasssesLSAKTCSLFLPNyvqdkyLLQLLRNADDVSTWVAAEIVT 1554
Cdd:pfam00617 5 QLTLIEFELFRKIKPRELLGSA-------------------WSKKDKKENSPN------IEAMIARFNKLSNWVASEILS 59
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116268127 1555 SHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAVRQ-SPAWRILPAKIAEVMEELKAV 1619
Cdd:pfam00617 60 EEDLKKRAKVIKKFIKIAEHCRELNNFNSLMAILSGLNSSPISRlKKTWELVSKKYKKTLEELEKL 125
|
|
| RasGEF |
smart00147 |
Guanine nucleotide exchange factor for Ras-like small GTPases; |
1464-1704 |
2.58e-21 |
|
Guanine nucleotide exchange factor for Ras-like small GTPases;
Pssm-ID: 214539 Cd Length: 242 Bit Score: 95.00 E-value: 2.58e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1464 LTEYSTHQLFSQLTLLQQELFQKCHPVHFLNSralgVMDKStaipkasSSESLSAKTcslflpnyvqdkyLLQLLRNADD 1543
Cdd:smart00147 1 LLLLDPKELAEQLTLLDFELFRKIDPSELLGS----VWGKR-------SKKSPSPLN-------------LEAFIRRFNE 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1544 VSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAV-RQSPAWRILPAKIAEVMEELKavEVF 1622
Cdd:smart00147 57 VSNWVATEILKQTTPKDRAELLSKFIQVAKHCRELNNFNSLMAIVSALSSSPIsRLKKTWEKLPSKYKKLFEELE--ELL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1623 LKSDSLClmEGRR-FRAQPTLPSAHLLAMHIQQLetggfTMT-NGAHRW--------SKLRNIAKVVSQVHAFQENPYTF 1692
Cdd:smart00147 135 SPERNYK--NYREaLSSCNLPPCIPFLGVLLKDL-----TFIdEGNPDFlenglvnfEKRRQIAEILREIRQLQSQPYNL 207
|
250
....*....|...
gi 116268127 1693 SPDPK-LQSYLKQ 1704
Cdd:smart00147 208 RPNRSdIQSLLQQ 220
|
|
| RasGEF |
cd00155 |
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of ... |
1464-1702 |
4.20e-20 |
|
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. Guanine-nucleotide-exchange factors (GEFs) positively regulate these GTP-binding proteins in response to a variety of signals. GEFs catalyze the dissociation of GDP from the inactive GTP-binding proteins. GTP can then bind and induce structural changes that allow interaction with effectors.
Pssm-ID: 238087 [Multi-domain] Cd Length: 237 Bit Score: 91.16 E-value: 4.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1464 LTEYSTHQLFSQLTLLQQELFQKCHPVHFLNSralGVMDKSTAIPKASSseslsaktcslflpnyvqdkyLLQLLRNADD 1543
Cdd:cd00155 1 FLSLDPKELAEQLTLLDFELFRKIEPFELLGS---LWSKKDKNIHLSPN---------------------LERFIERFNN 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1544 VSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAV-RQSPAWRILPAKIAEVMEELkaVEVF 1622
Cdd:cd00155 57 LSNWVASEILLCTNPKKRARLLSKFIQVAKHCRELNNFNSLMAIVSALSSSPIsRLKKTWEVLSSKLKKLFEEL--EELV 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1623 LKSDSLC-----LMEGrrFRAQPTLPsahLLAMHIQQLE-----TGGFTMTNGAHrWSKLRNIAKVVSQVHAFQENPYTF 1692
Cdd:cd00155 135 DPSRNFKnyrklLKSV--GPNPPCVP---FLGVYLKDLTflhegNPDFLEGNLVN-FEKRRKIAEILREIRQLQSNSYEL 208
|
250
....*....|
gi 116268127 1693 SPDPKLQSYL 1702
Cdd:cd00155 209 NRDEDILAFL 218
|
|
| REM |
cd06224 |
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also ... |
1254-1368 |
3.97e-18 |
|
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately N-terminal to the RasGef (Cdc25-like) domain. REM contacts the GTPase and is assumed to participate in the catalytic activity of the exchange factor. Proteins with the REM domain include Sos1 and Sos2, which relay signals from tyrosine-kinase mediated signalling to Ras, RasGRP1-4, RasGRF1,2, CNrasGEF, and RAP-specific nucleotide exchange factors, to name a few.
Pssm-ID: 100121 Cd Length: 122 Bit Score: 82.08 E-value: 3.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1254 TPLGLMAYLYSSDAFLE-GYVQQFLYTFRYFCTPHDFLHFLLDRIN---STLTRAHQDPTSTFTKIYRRSLCVLQAWVED 1329
Cdd:cd06224 1 TLEALIEHLTSTFDMPDpSFVSTFLLTYRSFTTPTELLEKLIERYEiapPENLEYNDWDKKKSKPIRLRVLNVLRTWVEN 80
|
90 100 110
....*....|....*....|....*....|....*....
gi 116268127 1330 CYaVDFPRNSGLLGKLEDFISSkILPLDGSAKHLLGLLE 1368
Cdd:cd06224 81 YP-YDFFDDEELLELLEEFLNR-LVQEGALLQELKKLLR 117
|
|
| RasGEF_N |
pfam00618 |
RasGEF N-terminal motif; A subset of guanine nucleotide exchange factor for Ras-like small ... |
1249-1348 |
4.80e-18 |
|
RasGEF N-terminal motif; A subset of guanine nucleotide exchange factor for Ras-like small GTPases appear to possess this motif/domain N-terminal to the RasGef (Cdc25-like) domain.
Pssm-ID: 459873 Cd Length: 104 Bit Score: 81.20 E-value: 4.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1249 ILQAGTPLGLMAYLYSSDAFLE-GYVQQFLYTFRYFCTPHDFLHFLLDR--INSTLTRAHQDPT--STFTKIYRRSLCVL 1323
Cdd:pfam00618 1 QVKAGTLEKLVEYLTSTRIMLDdSFLSTFLLTYRSFTTPAELLELLIERynIPPPLDLSSDSYWisKKTLPIRIRVLSVL 80
|
90 100
....*....|....*....|....*
gi 116268127 1324 QAWVEDCYaVDFPRNSGLLGKLEDF 1348
Cdd:pfam00618 81 RHWVENYF-SDFNDDPVLLSRLEKF 104
|
|
| RasGEFN |
smart00229 |
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif; A subset of guanine ... |
1248-1349 |
1.09e-08 |
|
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif; A subset of guanine nucleotide exchange factor for Ras-like small GTPases appear to possess this domain N-terminal to the RasGef (Cdc25-like) domain. The recent crystal structureof Sos shows that this domain is alpha-helical and plays a "purely structural role" (Nature 394, 337-343).
Pssm-ID: 214571 Cd Length: 127 Bit Score: 55.03 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1248 RILQAGTPLGLMAYL-YSSDAFLEGYVQQFLYTFRYFCTPHDFLHFLLDRINSTLTRAHQDPTSTFTKIYRRSLCVLQAW 1326
Cdd:smart00229 3 GLIKGGTLEALIEHLtEAFDKADPSFVETFLLTYRSFITTQELLQLLLYRYNAIPPESWVEEKVNPRRVKNRVLNILRTW 82
|
90 100
....*....|....*....|...
gi 116268127 1327 VEDcYAVDFPRNSGLLGKLEDFI 1349
Cdd:smart00229 83 VEN-YWEDFEDDPKLISFLLEFL 104
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
619-896 |
6.49e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.03 E-value: 6.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 619 SVVELKPSVAPAPEPSPGFLPVNSdtglvAVPGPvPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQE 698
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVS-----ATPLP-PGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPP 2767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 699 ESEERGGQRegegeeklsleahAGSPSLKTPDGPVPGPGPQGAAPEPLGASvqrDSAQGRPCPPPQAPANQPEGASSAAP 778
Cdd:PHA03247 2768 APAPPAAPA-------------AGPPRRLTRPAVASLSESRESLPSPWDPA---DPPAAVLAPAAALPPAASPAGPLPPP 2831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 779 GSPVPAPPTKASAlPVEqgPAEPIPPGVASGG---LRPDALGPTTAHHGPRHPP-----KPPRSKATERPGQEPEGPGAT 850
Cdd:PHA03247 2832 TSAQPTAPPPPPG-PPP--PSLPLGGSVAPGGdvrRRPPSRSPAAKPAAPARPPvrrlaRPAVSRSTESFALPPDQPERP 2908
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 116268127 851 P----AGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEA 896
Cdd:PHA03247 2909 PqpqaPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGA 2958
|
|
| KIND |
pfam16474 |
Kinase non-catalytic C-lobe domain; The KIND domain (kinase non-catalytic C-lobe domain) ... |
37-193 |
7.62e-06 |
|
Kinase non-catalytic C-lobe domain; The KIND domain (kinase non-catalytic C-lobe domain) evolved from a catalytic protein kinase fold and functions as an interaction domain. In SPIRE1 (protein spire homolog 1) this domain interacts with FMN2 (formin-2).
Pssm-ID: 465129 Cd Length: 196 Bit Score: 48.46 E-value: 7.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 37 VSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQSLCIT-PDTLAFNTSGNV-CFMEQLSDDPEGAFVPPEFDv 114
Cdd:pfam16474 1 LSLEEILKSYEQPINEEQAWAVCYQCCRGLRQPTRRRKQKFRRIRgPSDILLHRDGTVtLRFEASSDGPPKALLPARSE- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 115 tgntfEAHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRM----QAEDPGDRPD----------------------- 167
Cdd:pfam16474 80 -----TQVIQSLGVAIYKALDYGLKESEERELSPPLEQLIDLMtngdDEDGGQETDDegyeadeeeeeeedeegtissvr 154
|
170 180 190
....*....|....*....|....*....|..
gi 116268127 168 -LESIIALCEEKLQLTSSCR-----VCRSLSA 193
Cdd:pfam16474 155 tFRDVLKLCASHLPNPSDAPnhyqaVCRALFA 186
|
|
| SPS1 |
COG0515 |
Serine/threonine protein kinase [Signal transduction mechanisms]; |
123-349 |
6.97e-05 |
|
Serine/threonine protein kinase [Signal transduction mechanisms];
Pssm-ID: 440281 [Multi-domain] Cd Length: 482 Bit Score: 47.31 E-value: 6.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 123 IYSLGATLKAAL---------------------EYVAEPTLEPRLSQDLEALLSRMQAEDPGDRP-DLESIIALCEEKLQ 180
Cdd:COG0515 191 VYSLGVTLYELLtgrppfdgdspaellrahlrePPPPPSELRPDLPPALDAIVLRALAKDPEERYqSAAELAAALRAVLR 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 181 LTSSCRVCRSLSAVGRRVLSIESFGALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTK 260
Cdd:COG0515 271 SLAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAAAAAAAAALAAAAAAAAAAAAAA 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 261 ALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPD 340
Cdd:COG0515 351 LLAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAALAAAAAAAAAA 430
|
....*....
gi 116268127 341 PRKAFLDRK 349
Cdd:COG0515 431 AAAAAAAAA 439
|
|
| GGN |
pfam15685 |
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the ... |
777-895 |
2.20e-03 |
|
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the maturation of sperm and is expressed virtually only in the testis. It is found to be associated with the intracellular membrane, binds with GGNBP1 and may be involved in vesicular trafficking.
Pssm-ID: 434857 [Multi-domain] Cd Length: 668 Bit Score: 42.83 E-value: 2.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 777 APGSPVPA---PPTKASALPVEQGPAEPIPPGVASggLRPDALGPTTAHHGPRHPPKPPRSKATER---PGQEPEGPGAT 850
Cdd:pfam15685 405 GPRRPAPAllaPPMFIFPAPTNGEPVRPGPPAPQA--LLPRPPPPTPPATPPPVPPPIPQLPALQPmplAAARPPTPRPC 482
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 116268127 851 PAGERDDQSPDSVPERPRP-ADRRLCLPCVDASPLPGRTACPSLQE 895
Cdd:pfam15685 483 PGHGESALAPAPTAPLPPAlAADQAPAPALAAAPAPSPAPAPATAD 528
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| KIND |
smart00750 |
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to ... |
37-217 |
2.96e-50 |
|
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to the C-terminal protein kinase catalytic fold (C lobe). Its presence at the N terminus of signalling proteins and the absence of the active-site residues in the catalytic and activation loops suggest that it folds independently and is likely to be non-catalytic. The occurrence of KIND only in metazoa implies that it has evolved from the catalytic protein kinase domain into an interaction domain possibly by keeping the substrate-binding features
Pssm-ID: 214801 Cd Length: 176 Bit Score: 176.05 E-value: 2.96e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 37 VSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQSLCITPDTLAFNtSGNVCFMEQLSDDPEGAFVPPEFDVTG 116
Cdd:smart00750 1 VSLADILEVRGRPLNEEEIWAVCLQCLGALRELHRQAKSGNILLTWDGLLKL-DGSVAFKTPEQSRPDPYFMAPEVIQGQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 117 N-TFEAHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEeklqLTSSCRVCRSlSAVG 195
Cdd:smart00750 80 SyTEKADIYSLGITLYEALDYELPYNEERELSAILEILLNGMPADDPRDRSNLEGVSAARS----FEDFMRLCAS-RLPQ 154
|
170 180
....*....|....*....|..
gi 116268127 196 RRVLSIESFGALQDVSESSWRE 217
Cdd:smart00750 155 RREAANHYLAHCRALFAETLEL 176
|
|
| KIND |
smart00750 |
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to ... |
444-608 |
1.02e-45 |
|
kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to the C-terminal protein kinase catalytic fold (C lobe). Its presence at the N terminus of signalling proteins and the absence of the active-site residues in the catalytic and activation loops suggest that it folds independently and is likely to be non-catalytic. The occurrence of KIND only in metazoa implies that it has evolved from the catalytic protein kinase domain into an interaction domain possibly by keeping the substrate-binding features
Pssm-ID: 214801 Cd Length: 176 Bit Score: 162.95 E-value: 1.02e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 444 VSLQDLLSQLGRPFREYELWALCLACLRALQTRP----EHPAYLCLDSVLVAeDGAVLFQPPPANGSyDSFFLAPELAEE 519
Cdd:smart00750 1 VSLADILEVRGRPLNEEEIWAVCLQCLGALRELHrqakSGNILLTWDGLLKL-DGSVAFKTPEQSRP-DPYFMAPEVIQG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 520 RLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMARRSAP---------ERPSAAEAIKVCGSYLLQRGMD 590
Cdd:smart00750 79 QSYTEKADIYSLGITLYEALDYELPYNEERELSAILEILLNGMPADDPRdrsnlegvsAARSFEDFMRLCASRLPQRREA 158
|
170
....*....|....*...
gi 116268127 591 SRKILAHLRASICQVYQE 608
Cdd:smart00750 159 ANHYLAHCRALFAETLEL 176
|
|
| RasGEF |
pfam00617 |
RasGEF domain; Guanine nucleotide exchange factor for Ras-like small GTPases. |
1475-1619 |
5.47e-24 |
|
RasGEF domain; Guanine nucleotide exchange factor for Ras-like small GTPases.
Pssm-ID: 459872 Cd Length: 179 Bit Score: 100.74 E-value: 5.47e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1475 QLTLLQQELFQKCHPVHFLNSRalgvmdkstaipkasssesLSAKTCSLFLPNyvqdkyLLQLLRNADDVSTWVAAEIVT 1554
Cdd:pfam00617 5 QLTLIEFELFRKIKPRELLGSA-------------------WSKKDKKENSPN------IEAMIARFNKLSNWVASEILS 59
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116268127 1555 SHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAVRQ-SPAWRILPAKIAEVMEELKAV 1619
Cdd:pfam00617 60 EEDLKKRAKVIKKFIKIAEHCRELNNFNSLMAILSGLNSSPISRlKKTWELVSKKYKKTLEELEKL 125
|
|
| RasGEF |
smart00147 |
Guanine nucleotide exchange factor for Ras-like small GTPases; |
1464-1704 |
2.58e-21 |
|
Guanine nucleotide exchange factor for Ras-like small GTPases;
Pssm-ID: 214539 Cd Length: 242 Bit Score: 95.00 E-value: 2.58e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1464 LTEYSTHQLFSQLTLLQQELFQKCHPVHFLNSralgVMDKStaipkasSSESLSAKTcslflpnyvqdkyLLQLLRNADD 1543
Cdd:smart00147 1 LLLLDPKELAEQLTLLDFELFRKIDPSELLGS----VWGKR-------SKKSPSPLN-------------LEAFIRRFNE 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1544 VSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAV-RQSPAWRILPAKIAEVMEELKavEVF 1622
Cdd:smart00147 57 VSNWVATEILKQTTPKDRAELLSKFIQVAKHCRELNNFNSLMAIVSALSSSPIsRLKKTWEKLPSKYKKLFEELE--ELL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1623 LKSDSLClmEGRR-FRAQPTLPSAHLLAMHIQQLetggfTMT-NGAHRW--------SKLRNIAKVVSQVHAFQENPYTF 1692
Cdd:smart00147 135 SPERNYK--NYREaLSSCNLPPCIPFLGVLLKDL-----TFIdEGNPDFlenglvnfEKRRQIAEILREIRQLQSQPYNL 207
|
250
....*....|...
gi 116268127 1693 SPDPK-LQSYLKQ 1704
Cdd:smart00147 208 RPNRSdIQSLLQQ 220
|
|
| RasGEF |
cd00155 |
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of ... |
1464-1702 |
4.20e-20 |
|
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. Guanine-nucleotide-exchange factors (GEFs) positively regulate these GTP-binding proteins in response to a variety of signals. GEFs catalyze the dissociation of GDP from the inactive GTP-binding proteins. GTP can then bind and induce structural changes that allow interaction with effectors.
Pssm-ID: 238087 [Multi-domain] Cd Length: 237 Bit Score: 91.16 E-value: 4.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1464 LTEYSTHQLFSQLTLLQQELFQKCHPVHFLNSralGVMDKSTAIPKASSseslsaktcslflpnyvqdkyLLQLLRNADD 1543
Cdd:cd00155 1 FLSLDPKELAEQLTLLDFELFRKIEPFELLGS---LWSKKDKNIHLSPN---------------------LERFIERFNN 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1544 VSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAV-RQSPAWRILPAKIAEVMEELkaVEVF 1622
Cdd:cd00155 57 LSNWVASEILLCTNPKKRARLLSKFIQVAKHCRELNNFNSLMAIVSALSSSPIsRLKKTWEVLSSKLKKLFEEL--EELV 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1623 LKSDSLC-----LMEGrrFRAQPTLPsahLLAMHIQQLE-----TGGFTMTNGAHrWSKLRNIAKVVSQVHAFQENPYTF 1692
Cdd:cd00155 135 DPSRNFKnyrklLKSV--GPNPPCVP---FLGVYLKDLTflhegNPDFLEGNLVN-FEKRRKIAEILREIRQLQSNSYEL 208
|
250
....*....|
gi 116268127 1693 SPDPKLQSYL 1702
Cdd:cd00155 209 NRDEDILAFL 218
|
|
| REM |
cd06224 |
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also ... |
1254-1368 |
3.97e-18 |
|
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately N-terminal to the RasGef (Cdc25-like) domain. REM contacts the GTPase and is assumed to participate in the catalytic activity of the exchange factor. Proteins with the REM domain include Sos1 and Sos2, which relay signals from tyrosine-kinase mediated signalling to Ras, RasGRP1-4, RasGRF1,2, CNrasGEF, and RAP-specific nucleotide exchange factors, to name a few.
Pssm-ID: 100121 Cd Length: 122 Bit Score: 82.08 E-value: 3.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1254 TPLGLMAYLYSSDAFLE-GYVQQFLYTFRYFCTPHDFLHFLLDRIN---STLTRAHQDPTSTFTKIYRRSLCVLQAWVED 1329
Cdd:cd06224 1 TLEALIEHLTSTFDMPDpSFVSTFLLTYRSFTTPTELLEKLIERYEiapPENLEYNDWDKKKSKPIRLRVLNVLRTWVEN 80
|
90 100 110
....*....|....*....|....*....|....*....
gi 116268127 1330 CYaVDFPRNSGLLGKLEDFISSkILPLDGSAKHLLGLLE 1368
Cdd:cd06224 81 YP-YDFFDDEELLELLEEFLNR-LVQEGALLQELKKLLR 117
|
|
| RasGEF_N |
pfam00618 |
RasGEF N-terminal motif; A subset of guanine nucleotide exchange factor for Ras-like small ... |
1249-1348 |
4.80e-18 |
|
RasGEF N-terminal motif; A subset of guanine nucleotide exchange factor for Ras-like small GTPases appear to possess this motif/domain N-terminal to the RasGef (Cdc25-like) domain.
Pssm-ID: 459873 Cd Length: 104 Bit Score: 81.20 E-value: 4.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1249 ILQAGTPLGLMAYLYSSDAFLE-GYVQQFLYTFRYFCTPHDFLHFLLDR--INSTLTRAHQDPT--STFTKIYRRSLCVL 1323
Cdd:pfam00618 1 QVKAGTLEKLVEYLTSTRIMLDdSFLSTFLLTYRSFTTPAELLELLIERynIPPPLDLSSDSYWisKKTLPIRIRVLSVL 80
|
90 100
....*....|....*....|....*
gi 116268127 1324 QAWVEDCYaVDFPRNSGLLGKLEDF 1348
Cdd:pfam00618 81 RHWVENYF-SDFNDDPVLLSRLEKF 104
|
|
| RasGEFN |
smart00229 |
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif; A subset of guanine ... |
1248-1349 |
1.09e-08 |
|
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif; A subset of guanine nucleotide exchange factor for Ras-like small GTPases appear to possess this domain N-terminal to the RasGef (Cdc25-like) domain. The recent crystal structureof Sos shows that this domain is alpha-helical and plays a "purely structural role" (Nature 394, 337-343).
Pssm-ID: 214571 Cd Length: 127 Bit Score: 55.03 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 1248 RILQAGTPLGLMAYL-YSSDAFLEGYVQQFLYTFRYFCTPHDFLHFLLDRINSTLTRAHQDPTSTFTKIYRRSLCVLQAW 1326
Cdd:smart00229 3 GLIKGGTLEALIEHLtEAFDKADPSFVETFLLTYRSFITTQELLQLLLYRYNAIPPESWVEEKVNPRRVKNRVLNILRTW 82
|
90 100
....*....|....*....|...
gi 116268127 1327 VEDcYAVDFPRNSGLLGKLEDFI 1349
Cdd:smart00229 83 VEN-YWEDFEDDPKLISFLLEFL 104
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
619-896 |
6.49e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.03 E-value: 6.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 619 SVVELKPSVAPAPEPSPGFLPVNSdtglvAVPGPvPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQE 698
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVS-----ATPLP-PGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPP 2767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 699 ESEERGGQRegegeeklsleahAGSPSLKTPDGPVPGPGPQGAAPEPLGASvqrDSAQGRPCPPPQAPANQPEGASSAAP 778
Cdd:PHA03247 2768 APAPPAAPA-------------AGPPRRLTRPAVASLSESRESLPSPWDPA---DPPAAVLAPAAALPPAASPAGPLPPP 2831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 779 GSPVPAPPTKASAlPVEqgPAEPIPPGVASGG---LRPDALGPTTAHHGPRHPP-----KPPRSKATERPGQEPEGPGAT 850
Cdd:PHA03247 2832 TSAQPTAPPPPPG-PPP--PSLPLGGSVAPGGdvrRRPPSRSPAAKPAAPARPPvrrlaRPAVSRSTESFALPPDQPERP 2908
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 116268127 851 P----AGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEA 896
Cdd:PHA03247 2909 PqpqaPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGA 2958
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
629-922 |
1.43e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 53.79 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 629 PAPEPSPGFLPVNSDTGLVAVPGPVPGqhpcGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQRe 708
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAA----RQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPA- 2776
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 709 gegeeklsleahAGSPSLKTPDGPVPGPGPQGAAPEPLGASvqrDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTK 788
Cdd:PHA03247 2777 ------------AGPPRRLTRPAVASLSESRESLPSPWDPA---DPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPP 2841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 789 ASAlPVEqgPAEPIPPGVASGG---LRPDALGPTTAhhgPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPE 865
Cdd:PHA03247 2842 PPG-PPP--PSLPLGGSVAPGGdvrRRPPSRSPAAK---PAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPP 2915
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 116268127 866 RPRPADRRLCLPCVDASPLPGRTACPSLQEATRLIQEEFAFDGYLDNGLEALIMGEY 922
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRV 2972
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
640-872 |
5.07e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 51.53 E-value: 5.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 640 VNSDTGLVAVPGPVPGQHpcGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEA 719
Cdd:PRK07764 578 LGGDWQVEAVVGPAPGAA--GGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPK 655
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 720 HAGSP--SLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGrpcpppqapanqpegassAAPGSPVPAPPTKASALPVEQG 797
Cdd:PRK07764 656 HVAVPdaSDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAG------------------AAPAQPAPAPAATPPAGQADDP 717
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116268127 798 PAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGAtPAGERDDQSPDSVPERPRPADR 872
Cdd:PRK07764 718 AAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAA-PAAAPPPSPPSEEEEMAEDDAP 791
|
|
| KIND |
pfam16474 |
Kinase non-catalytic C-lobe domain; The KIND domain (kinase non-catalytic C-lobe domain) ... |
37-193 |
7.62e-06 |
|
Kinase non-catalytic C-lobe domain; The KIND domain (kinase non-catalytic C-lobe domain) evolved from a catalytic protein kinase fold and functions as an interaction domain. In SPIRE1 (protein spire homolog 1) this domain interacts with FMN2 (formin-2).
Pssm-ID: 465129 Cd Length: 196 Bit Score: 48.46 E-value: 7.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 37 VSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQSLCIT-PDTLAFNTSGNV-CFMEQLSDDPEGAFVPPEFDv 114
Cdd:pfam16474 1 LSLEEILKSYEQPINEEQAWAVCYQCCRGLRQPTRRRKQKFRRIRgPSDILLHRDGTVtLRFEASSDGPPKALLPARSE- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 115 tgntfEAHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRM----QAEDPGDRPD----------------------- 167
Cdd:pfam16474 80 -----TQVIQSLGVAIYKALDYGLKESEERELSPPLEQLIDLMtngdDEDGGQETDDegyeadeeeeeeedeegtissvr 154
|
170 180 190
....*....|....*....|....*....|..
gi 116268127 168 -LESIIALCEEKLQLTSSCR-----VCRSLSA 193
Cdd:pfam16474 155 tFRDVLKLCASHLPNPSDAPnhyqaVCRALFA 186
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
629-892 |
4.48e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.78 E-value: 4.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 629 PAPEPSPGFLPVNSDTglvAVPGPVPGQHPCGeeatqlPAAFTSEAthfKPIVLAQNAS----VARDQPALAQEESEERG 704
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDR---SVPPPRPAPRPSE------PAVTSRAR---RPDAPPQSARprapVDDRGDPRGPAPPSPLP 2618
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 705 GQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGS---- 780
Cdd:PHA03247 2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltsl 2698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 781 --PVPAPPTKASAlPVEQGPAEPIPPGVASGGlrpDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPgATPAGERDDQ 858
Cdd:PHA03247 2699 adPPPPPPTPEPA-PHALVSATPLPPGPAAAR---QASPALPAAPAPPAVPAGPATPGGPARPARPPTT-AGPPAPAPPA 2773
|
250 260 270
....*....|....*....|....*....|....*.
gi 116268127 859 SPDSVPER--PRPADRRLClPCVDASPLPGRTACPS 892
Cdd:PHA03247 2774 APAAGPPRrlTRPAVASLS-ESRESLPSPWDPADPP 2808
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
648-898 |
5.44e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.95 E-value: 5.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 648 AVPGPVPGQHPCGEEATQLPAAFTSEATHfkpiVLAQNASVARDQPALAQEE-----------------SEERGGQREGE 710
Cdd:PRK12323 302 VVPAAVQDDWPEADDIRRLAGRFDAQEVQ----LFYQIANLGRSELALAPDEyagftmtllrmlafrpgQSGGGAGPATA 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 711 GEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKAS 790
Cdd:PRK12323 378 AAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAA 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 791 ALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPA 870
Cdd:PRK12323 458 PAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDA 537
|
250 260
....*....|....*....|....*...
gi 116268127 871 dRRLCLPCVDASPLPGRTACPSLQEATR 898
Cdd:PRK12323 538 -FETLAPAPAAAPAPRAAAATEPVVAPR 564
|
|
| SPS1 |
COG0515 |
Serine/threonine protein kinase [Signal transduction mechanisms]; |
123-349 |
6.97e-05 |
|
Serine/threonine protein kinase [Signal transduction mechanisms];
Pssm-ID: 440281 [Multi-domain] Cd Length: 482 Bit Score: 47.31 E-value: 6.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 123 IYSLGATLKAAL---------------------EYVAEPTLEPRLSQDLEALLSRMQAEDPGDRP-DLESIIALCEEKLQ 180
Cdd:COG0515 191 VYSLGVTLYELLtgrppfdgdspaellrahlrePPPPPSELRPDLPPALDAIVLRALAKDPEERYqSAAELAAALRAVLR 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 181 LTSSCRVCRSLSAVGRRVLSIESFGALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTK 260
Cdd:COG0515 271 SLAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAAAAAAAAALAAAAAAAAAAAAAA 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 261 ALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPD 340
Cdd:COG0515 351 LLAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAALAAAAAAAAAA 430
|
....*....
gi 116268127 341 PRKAFLDRK 349
Cdd:COG0515 431 AAAAAAAAA 439
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
773-873 |
1.58e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 46.34 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 773 ASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPdalgPTTAHHGPRHPPK-PPRSKATERPGQEPEGPGATP 851
Cdd:PRK14950 358 ALLVPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIP----PKEPVRETATPPPvPPRPVAPPVPHTPESAPKLTR 433
|
90 100
....*....|....*....|..
gi 116268127 852 AGERDDQSPDSVPERPRPADRR 873
Cdd:PRK14950 434 AAIPVDEKPKYTPPAPPKEEEK 455
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
719-892 |
2.09e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 719 AHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQ--RDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQ 796
Cdd:PRK07764 594 AAGGEGPPAPASSGPPEEAARPAAPAAPAAPAApaPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKA 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 797 GPAEPI-PPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPegPGATPAGERDDQSPDSVPERPRPADRRLC 875
Cdd:PRK07764 674 GGAAPAaPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPP--QAAQGASAPSPAADDPVPLPPEPDDPPDP 751
|
170
....*....|....*..
gi 116268127 876 LPCVDASPLPGRTACPS 892
Cdd:PRK07764 752 AGAPAQPPPPPAPAPAA 768
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
629-897 |
3.07e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.08 E-value: 3.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 629 PAPEPSPGFLPVNSDTGLVAVP-----GPVPGQhPCGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEER 703
Cdd:PHA03247 2571 PRPAPRPSEPAVTSRARRPDAPpqsarPRAPVD-DRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPP 2649
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 704 GGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASvqrdSAQGRPCPPPQAPANQPEGASSAAPGSPVP 783
Cdd:PHA03247 2650 ERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL----TSLADPPPPPPTPEPAPHALVSATPLPPGP 2725
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 784 APPTKASALPveqgPAEPIPPGVASGGLRPDALGPTTAhhgPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSV 863
Cdd:PHA03247 2726 AAARQASPAL----PAAPAPPAVPAGPATPGGPARPAR---PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESL 2798
|
250 260 270
....*....|....*....|....*....|....
gi 116268127 864 PERPRPADRRLCLPCVDASPLPGRTACPSLQEAT 897
Cdd:PHA03247 2799 PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT 2832
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
355-891 |
3.69e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.70 E-value: 3.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 355 FQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPADPRDAS---GEAQTPRDD--ERIP 429
Cdd:PHA03247 2474 FPGAPVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRMLTwirGLEELASDDagDPPP 2553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 430 EGARQLESAAAEQWVSLQDLLSQLGRPfreyelwalclaCLRALQTRPEHPAYLCLDSVLVAEDGAVLFQPPPANGSYDS 509
Cdd:PHA03247 2554 PLPPAAPPAAPDRSVPPPRPAPRPSEP------------AVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDT 2621
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 510 FFLAPELAEERLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMARRSAPERPSAAEAIKVCGSYL-LQRG 588
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTsLADP 2701
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 589 MDSRKILAHL-RASICQVYQEEETISLQNAFSVvelkPSVAPAPEPSPGfLPVnSDTGLVAVPGPvpgQHPCGEEATQLP 667
Cdd:PHA03247 2702 PPPPPTPEPApHALVSATPLPPGPAAARQASPA----LPAAPAPPAVPA-GPA-TPGGPARPARP---PTTAGPPAPAPP 2772
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 668 AAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAP-EPL 746
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPsLPL 2852
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 747 GASVqrdsAQGRPCP--PPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHG 824
Cdd:PHA03247 2853 GGSV----APGGDVRrrPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 116268127 825 PRHPPK-PPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPrPADRRLCLPCVDASPLPGRTACP 891
Cdd:PHA03247 2929 PQPPPPpPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRV-AVPRFRVPQPAPSREAPASSTPP 2995
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
625-885 |
5.17e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.84 E-value: 5.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 625 PSVAPAPEPSPgflPVNSDTGLVAVPGPVPGQHPcgEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERG 704
Cdd:PRK07003 422 RAEAPPAAPAP---PATADRGDDAADGDAPVPAK--ANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRA 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 705 GQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQG-------RPCPPPQAPANQPEGASSAA 777
Cdd:PRK07003 497 AAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAaaaldvlRNAGMRVSSDRGARAAAAAK 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 778 PGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPP---KPPRSKAterPGQEPEGPGATPAGE 854
Cdd:PRK07003 577 PAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPwedIPPDDYV---PLSADEGFGGPDDGF 653
|
250 260 270
....*....|....*....|....*....|...
gi 116268127 855 RD--DQSPDSVPERPRPADRRlcLPCVDASPLP 885
Cdd:PRK07003 654 VPvfDSGPDDVRVAPKPADAP--APPVDTRPLP 684
|
|
| PHA03264 |
PHA03264 |
envelope glycoprotein D; Provisional |
775-873 |
5.18e-04 |
|
envelope glycoprotein D; Provisional
Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 44.61 E-value: 5.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 775 SAAPGSPVPAPPTKASALPvEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHP-PKPPRSKAterPGQEPEGPGATPAG 853
Cdd:PHA03264 269 APSGGSPAPPGDDRPEAKP-EPGPVEDGAPGRETGGEGEGPEPAGRDGAAGGEPkPGPPRPAP---DADRPEGWPSLEAI 344
|
90 100
....*....|....*....|
gi 116268127 854 ERddqsPDSVPERPRPADRR 873
Cdd:PHA03264 345 TF----PPPTPATPAVPRAR 360
|
|
| PHA03264 |
PHA03264 |
envelope glycoprotein D; Provisional |
785-900 |
7.32e-04 |
|
envelope glycoprotein D; Provisional
Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 44.23 E-value: 7.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 785 PPTKASALPVEQGPA----EPIPPGVASGGLRPDAlgpttahhGPRHPPKPPRSKATERPGQEPEGPGATPAGErddqsP 860
Cdd:PHA03264 255 PPYFEESKGYEPPPApsggSPAPPGDDRPEAKPEP--------GPVEDGAPGRETGGEGEGPEPAGRDGAAGGE-----P 321
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 116268127 861 DSVPERPRP-ADRRLCLPCVDASPLPGRT-ACPSLQEATRLI 900
Cdd:PHA03264 322 KPGPPRPAPdADRPEGWPSLEAITFPPPTpATPAVPRARPVI 363
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
772-898 |
7.77e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.46 E-value: 7.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 772 GASSAAPGSPVPAP-PTKASALPVEQGPAEPIPPGVASGGLRPDA---LGPTTAHHGPRHPPKPPRSKATERPGQEPEG- 846
Cdd:PRK07003 370 GGVPARVAGAVPAPgARAAAAVGASAVPAVTAVTGAAGAALAPKAaaaAAATRAEAPPAAPAPPATADRGDDAADGDAPv 449
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 116268127 847 PGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEATR 898
Cdd:PRK07003 450 PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSA 501
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
741-872 |
1.91e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.05 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 741 AAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGglrPDALGPTT 820
Cdd:PRK07764 366 SASDDERGLLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPA---PAPAPAPP 442
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 116268127 821 AHHGPRHPPKPPRSKATERPGQEPeGPGATPAGERDDQSPDSVPERPRPADR 872
Cdd:PRK07764 443 SPAGNAPAGGAPSPPPAAAPSAQP-APAPAAAPEPTAAPAPAPPAAPAPAAA 493
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
775-870 |
2.12e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 43.13 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 775 SAAPGS--PVPAPPTKASALPVEQGPAEP--------IPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEP 844
Cdd:PHA03378 688 QWAPGTmqPPPRAPTPMRPPAAPPGRAQRpaaatgraRPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPP 767
|
90 100
....*....|....*....|....*.
gi 116268127 845 EGPGATPAGERDDQSPDSVPERPRPA 870
Cdd:PHA03378 768 AAAPGAPTPQPPPQAPPAPQQRPRGA 793
|
|
| GGN |
pfam15685 |
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the ... |
777-895 |
2.20e-03 |
|
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the maturation of sperm and is expressed virtually only in the testis. It is found to be associated with the intracellular membrane, binds with GGNBP1 and may be involved in vesicular trafficking.
Pssm-ID: 434857 [Multi-domain] Cd Length: 668 Bit Score: 42.83 E-value: 2.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268127 777 APGSPVPA---PPTKASALPVEQGPAEPIPPGVASggLRPDALGPTTAHHGPRHPPKPPRSKATER---PGQEPEGPGAT 850
Cdd:pfam15685 405 GPRRPAPAllaPPMFIFPAPTNGEPVRPGPPAPQA--LLPRPPPPTPPATPPPVPPPIPQLPALQPmplAAARPPTPRPC 482
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 116268127 851 PAGERDDQSPDSVPERPRP-ADRRLCLPCVDASPLPGRTACPSLQE 895
Cdd:pfam15685 483 PGHGESALAPAPTAPLPPAlAADQAPAPALAAAPAPSPAPAPATAD 528
|
|
| |
