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Conserved domains on  [gi|258547124|ref|NP_848621|]
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mitochondrial coenzyme A transporter SLC25A42 [Homo sapiens]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 34-295 4.96e-25

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 102.15  E-value: 4.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124  34 LSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAfRVLYYTYL---------NEGFLSLWRGNSATMVRVVPYA 104
Cdd:PTZ00169   8 ATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSG-KVPRYSGIvncfrrvskEQGVLSLWRGNTANVIRYFPTQ 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124 105 AIQFSAHEEYKRILGSY------YGFRGealppwPRLFAGALAGTTAASLTYPLDLVRARMAV----TPKEMYSNIFHVF 174
Cdd:PTZ00169  87 AFNFAFKDYFKNMFPKYnqktdfWKFFG------VNILSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124 175 IRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHreYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRR- 253
Cdd:PTZ00169 161 MKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL--FGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRm 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 258547124 254 MQTAGVTGYPRASIARTL---RTIVREEGaVRGLYKGLSMNWVKG 295
Cdd:PTZ00169 239 MMMSGRKAKSEIQYTGTLdcwKKILKNEG-LGGFFKGAWANVLRG 282
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 34-295 4.96e-25

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 102.15  E-value: 4.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124  34 LSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAfRVLYYTYL---------NEGFLSLWRGNSATMVRVVPYA 104
Cdd:PTZ00169   8 ATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSG-KVPRYSGIvncfrrvskEQGVLSLWRGNTANVIRYFPTQ 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124 105 AIQFSAHEEYKRILGSY------YGFRGealppwPRLFAGALAGTTAASLTYPLDLVRARMAV----TPKEMYSNIFHVF 174
Cdd:PTZ00169  87 AFNFAFKDYFKNMFPKYnqktdfWKFFG------VNILSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124 175 IRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHreYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRR- 253
Cdd:PTZ00169 161 MKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL--FGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRm 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 258547124 254 MQTAGVTGYPRASIARTL---RTIVREEGaVRGLYKGLSMNWVKG 295
Cdd:PTZ00169 239 MMMSGRKAKSEIQYTGTLdcwKKILKNEG-LGGFFKGAWANVLRG 282
Mito_carr pfam00153
Mitochondrial carrier protein;
29-122 7.98e-25

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 95.80  E-value: 7.98e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124   29 DHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKE--AFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAI 106
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGrgILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*.
gi 258547124  107 QFSAHEEYKRILGSYY 122
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 34-295 4.96e-25

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 102.15  E-value: 4.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124  34 LSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAfRVLYYTYL---------NEGFLSLWRGNSATMVRVVPYA 104
Cdd:PTZ00169   8 ATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSG-KVPRYSGIvncfrrvskEQGVLSLWRGNTANVIRYFPTQ 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124 105 AIQFSAHEEYKRILGSY------YGFRGealppwPRLFAGALAGTTAASLTYPLDLVRARMAV----TPKEMYSNIFHVF 174
Cdd:PTZ00169  87 AFNFAFKDYFKNMFPKYnqktdfWKFFG------VNILSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124 175 IRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHreYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRR- 253
Cdd:PTZ00169 161 MKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL--FGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRm 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 258547124 254 MQTAGVTGYPRASIARTL---RTIVREEGaVRGLYKGLSMNWVKG 295
Cdd:PTZ00169 239 MMMSGRKAKSEIQYTGTLdcwKKILKNEG-LGGFFKGAWANVLRG 282
Mito_carr pfam00153
Mitochondrial carrier protein;
29-122 7.98e-25

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 95.80  E-value: 7.98e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124   29 DHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKE--AFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAI 106
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGrgILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*.
gi 258547124  107 QFSAHEEYKRILGSYY 122
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
Mito_carr pfam00153
Mitochondrial carrier protein;
223-315 1.87e-22

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 89.64  E-value: 1.87e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124  223 QPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTG-YPRASIARTLRTIVREEGaVRGLYKGLSMNWVKGPIAVGI 301
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGkSKGRGILDCFKKIYKEEG-IRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....
gi 258547124  302 SFTTFDLMQILLRH 315
Cdd:pfam00153  81 YFGTYETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
147-214 3.08e-20

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 83.47  E-value: 3.08e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 258547124  147 SLTYPLDLVRARMAVTP---KEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSL 214
Cdd:pfam00153  21 TVTYPLDVVKTRLQVQGgsgKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTYETLKRL 91
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 34-287 1.36e-07

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 51.85  E-value: 1.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124  34 LSSLLSGALAGALAKTAVAPLDRTKIIFQvsskrfsAKEAFRVLYYTYLNEGFLslwrgnsATMVRVVPYAAIQFSAHEE 113
Cdd:PTZ00168   4 FHNLVTGALSGVIVDAVLYPIDSIKTNIQ-------AKKSFSFSDIKKLYSGIL-------PTLVGTVPASAFFYCFYEL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124 114 YKRILGSYygfRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKemySNIFHVFIRISREEGLKT-LYHGFMP 192
Cdd:PTZ00168  70 SKKLLTEY---RENISKTNLYLISTSIAEITACIVRLPFEIVKQNMQVSGN---ISVLKTIYEITQREGLPSfLGKSYFV 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258547124 193 TVLGVIPYAGLSFFTYETLKS-LHREYSGRRQPYP-FERMIFGACAGLIGQSASYPLDVVRRRMQTAGvtgyprASIART 270
Cdd:PTZ00168 144 MIVREIPFDCIQYFLWETLKEkAKKDFGKFSKKYPsITSAICGGLAGGIAGFLTTPVDVIKSRQIIYG------KSYIET 217

                        250
                 ....*....|....*..
gi 258547124 271 LRTIvrEEGAVRGLYKG 287
Cdd:PTZ00168 218 VTEI--AEEGYLTFYKG 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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