LBP (lipopolysaccharide-binding protein)/BPI (bactericidal permeability-increasing protein)/CETP (cholesteryl ester transfer protein) family protein similar to Homo sapiens BPI fold-containing family B member 6 and Gallus gallus cholesteryl ester transfer protein
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
21-225
3.64e-38
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
:
Pssm-ID: 237992 Cd Length: 223 Bit Score: 138.28 E-value: 3.64e-38
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / ...
252-445
1.19e-16
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
The actual alignment was detected with superfamily member smart00329:
Pssm-ID: 412206 Cd Length: 202 Bit Score: 78.12 E-value: 1.19e-16
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
21-225
3.64e-38
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
Pssm-ID: 237992 Cd Length: 223 Bit Score: 138.28 E-value: 3.64e-38
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
252-445
1.19e-16
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain
Pssm-ID: 128624 Cd Length: 202 Bit Score: 78.12 E-value: 1.19e-16
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
253-445
1.38e-16
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
Pssm-ID: 237993 Cd Length: 200 Bit Score: 78.11 E-value: 1.38e-16
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
64-220
1.43e-11
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain
Pssm-ID: 214622 [Multi-domain] Cd Length: 225 Bit Score: 63.95 E-value: 1.43e-11
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
21-225
3.64e-38
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
Pssm-ID: 237992 Cd Length: 223 Bit Score: 138.28 E-value: 3.64e-38
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / ...
23-222
8.74e-24
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
Pssm-ID: 238164 Cd Length: 208 Bit Score: 98.61 E-value: 8.74e-24
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
252-445
1.19e-16
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain
Pssm-ID: 128624 Cd Length: 202 Bit Score: 78.12 E-value: 1.19e-16
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
253-445
1.38e-16
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
Pssm-ID: 237993 Cd Length: 200 Bit Score: 78.11 E-value: 1.38e-16
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / ...
64-220
1.43e-11
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain
Pssm-ID: 214622 [Multi-domain] Cd Length: 225 Bit Score: 63.95 E-value: 1.43e-11
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / ...
253-449
1.75e-05
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
Pssm-ID: 238164 Cd Length: 208 Bit Score: 45.46 E-value: 1.75e-05
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
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(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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specific hits meet or exceed a domain-specific e-value threshold
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