NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|41053411|ref|NP_956969|]
View 

protein RER1 [Danio rerio]

Protein Classification

Rer1 family protein( domain architecture ID 10505457)

retention in endoplasmic reticulum sorting receptor 1 (Rer1) family protein such as human RER1, which is involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Rer1 pfam03248
Rer1 family; RER1 family protein are involved in involved in the retrieval of some endoplasmic ...
 21-184 1.75e-107

Rer1 family; RER1 family protein are involved in involved in the retrieval of some endoplasmic reticulum membrane proteins from the early golgi compartment. The C terminus of yeast Rer1p interacts with a coatomer complex.


:

Pssm-ID: 460860  Cd Length: 167  Bit Score: 304.84  E-value: 1.75e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411    21 FFKRLGQIYQSWLDKSTPFSAVRWASTLILTAIYMIRVYILQGWYIVTYALGIYHLNLFIAFLSPKVDPSLLDDPDE-GP 99
Cdd:pfam03248   2 WKHKLSRKYQHYLDKSTPHTKYRWIGFLVLLLLFLLRIYLVQGWYIVTYALGIYLLNLFIAFLTPKFDPSLEQDELEdGP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411   100 ALPTKQNEEFRPFIRRLPEFKFWHSATKGIVIAMICTFFDAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYLPFTH 179
Cdd:pfam03248  82 SLPTKNDDEFRPFIRRLPEFKFWYSSTRATLIALFCTFFSIFDIPVFWPILLMYFIVLFVLTMRRQIKHMIKYKYVPFDF 161


                  ....*
gi 41053411   180 GKRTY 184
Cdd:pfam03248 162 GKKKY 166
 
Name Accession Description Interval E-value
Rer1 pfam03248
Rer1 family; RER1 family protein are involved in involved in the retrieval of some endoplasmic ...
 21-184 1.75e-107

Rer1 family; RER1 family protein are involved in involved in the retrieval of some endoplasmic reticulum membrane proteins from the early golgi compartment. The C terminus of yeast Rer1p interacts with a coatomer complex.


Pssm-ID: 460860  Cd Length: 167  Bit Score: 304.84  E-value: 1.75e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411    21 FFKRLGQIYQSWLDKSTPFSAVRWASTLILTAIYMIRVYILQGWYIVTYALGIYHLNLFIAFLSPKVDPSLLDDPDE-GP 99
Cdd:pfam03248   2 WKHKLSRKYQHYLDKSTPHTKYRWIGFLVLLLLFLLRIYLVQGWYIVTYALGIYLLNLFIAFLTPKFDPSLEQDELEdGP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411   100 ALPTKQNEEFRPFIRRLPEFKFWHSATKGIVIAMICTFFDAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYLPFTH 179
Cdd:pfam03248  82 SLPTKNDDEFRPFIRRLPEFKFWYSSTRATLIALFCTFFSIFDIPVFWPILLMYFIVLFVLTMRRQIKHMIKYKYVPFDF 161


                  ....*
gi 41053411   180 GKRTY 184
Cdd:pfam03248 162 GKKKY 166
RER1 COG5249
Golgi protein involved in Golgi-to-ER retrieval [Intracellular trafficking and secretion];
20-185 1.28e-63

Golgi protein involved in Golgi-to-ER retrieval [Intracellular trafficking and secretion];


Pssm-ID: 227574  Cd Length: 180  Bit Score: 194.69  E-value: 1.28e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411  20 NFFKRLgqiYQSWLDKSTPFSAVRWASTLILTAIYMIRVYILQGWYIVTYALGIYHLNLFIAFLSPKVDPSLLDDPDEGP 99
Cdd:COG5249  16 NDLKTL---YQHYLDRLAPRPDVRWGITGGLFLLFCIRIWSTGGWYLICYCLGIYLLNAFLAFLTPKFDMSFEQIEDDDE 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411 100 ALPTKQNEEFRPFIRRLPEFKFWHSATKGIVIAMICTFFDAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYLPFTH 179
Cdd:COG5249  93 IEEGEKDNEFRPFIRRLPEFKFWYFSTRATGMALIGSYFGIFDVPVFWPILVVYFIFLVFYTARRQIQHMKKYRYNPFDI 172


                ....*.
gi 41053411 180 GKRTYR 185
Cdd:COG5249 173 GKKKYK 178
 
Name Accession Description Interval E-value
Rer1 pfam03248
Rer1 family; RER1 family protein are involved in involved in the retrieval of some endoplasmic ...
 21-184 1.75e-107

Rer1 family; RER1 family protein are involved in involved in the retrieval of some endoplasmic reticulum membrane proteins from the early golgi compartment. The C terminus of yeast Rer1p interacts with a coatomer complex.


Pssm-ID: 460860  Cd Length: 167  Bit Score: 304.84  E-value: 1.75e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411    21 FFKRLGQIYQSWLDKSTPFSAVRWASTLILTAIYMIRVYILQGWYIVTYALGIYHLNLFIAFLSPKVDPSLLDDPDE-GP 99
Cdd:pfam03248   2 WKHKLSRKYQHYLDKSTPHTKYRWIGFLVLLLLFLLRIYLVQGWYIVTYALGIYLLNLFIAFLTPKFDPSLEQDELEdGP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411   100 ALPTKQNEEFRPFIRRLPEFKFWHSATKGIVIAMICTFFDAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYLPFTH 179
Cdd:pfam03248  82 SLPTKNDDEFRPFIRRLPEFKFWYSSTRATLIALFCTFFSIFDIPVFWPILLMYFIVLFVLTMRRQIKHMIKYKYVPFDF 161


                  ....*
gi 41053411   180 GKRTY 184
Cdd:pfam03248 162 GKKKY 166
RER1 COG5249
Golgi protein involved in Golgi-to-ER retrieval [Intracellular trafficking and secretion];
20-185 1.28e-63

Golgi protein involved in Golgi-to-ER retrieval [Intracellular trafficking and secretion];


Pssm-ID: 227574  Cd Length: 180  Bit Score: 194.69  E-value: 1.28e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411  20 NFFKRLgqiYQSWLDKSTPFSAVRWASTLILTAIYMIRVYILQGWYIVTYALGIYHLNLFIAFLSPKVDPSLLDDPDEGP 99
Cdd:COG5249  16 NDLKTL---YQHYLDRLAPRPDVRWGITGGLFLLFCIRIWSTGGWYLICYCLGIYLLNAFLAFLTPKFDMSFEQIEDDDE 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053411 100 ALPTKQNEEFRPFIRRLPEFKFWHSATKGIVIAMICTFFDAFNVPVFWPILVMYFIMLFCITMKRQIKHMIKYRYLPFTH 179
Cdd:COG5249  93 IEEGEKDNEFRPFIRRLPEFKFWYFSTRATGMALIGSYFGIFDVPVFWPILVVYFIFLVFYTARRQIQHMKKYRYNPFDI 172


                ....*.
gi 41053411 180 GKRTYR 185
Cdd:COG5249 173 GKKKYK 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH