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Conserved domains on  [gi|229577012|ref|NP_957132|]
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golgin subfamily A member 1 [Danio rerio]

Protein Classification

GRIP and coiled-coil domain-containing protein; GRIP and coiled-coil domain-containing protein; GRIP domain-containing protein; GRIP domain-containing protein; GRIP domain-containing protein( domain architecture ID 13531264)

GRIP (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain-containing protein; similar to Eremothecium gossypii golgin IMH1 which is involved in vesicular transport between an endosomal compartment and the Golgi apparatus; GRIP (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain-containing protein; similar to Eremothecium gossypii golgin IMH1 which is involved in vesicular transport between an endosomal compartment and the Golgi apparatus; GRIP (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain-containing protein; similar to Eremothecium gossypii golgin IMH1 which is involved in vesicular transport between an endosomal compartment and the Golgi apparatus; GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure; GRIP domain-containing protein; GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
160-719 1.69e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.23  E-value: 1.69e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 160 LFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQA 239
Cdd:COG1196  230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 240 QRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERE 319
Cdd:COG1196  310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 320 RILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLV 399
Cdd:COG1196  390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 400 KHKDDSSKAYRERTDAQISDLEQRLADcaekmksLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEE 479
Cdd:COG1196  470 EEAALLEAALAELLEELAEAAARLLLL-------LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEA 542
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 480 ELLAVQRDRETEankyqdNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVS--VEIAKALEETRKQREE 557
Cdd:COG1196  543 ALAAALQNIVVE------DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGaaVDLVASDLREADARYY 616
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 558 LQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVL 637
Cdd:COG1196  617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 638 RQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTL 717
Cdd:COG1196  697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776

                 ..
gi 229577012 718 QK 719
Cdd:COG1196  777 EA 778
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
788-833 8.66e-11

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 57.62  E-value: 8.66e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 229577012   788 EINFEYLKHVVLKFMSSREAEAFQLIRAVSVLLHFSKEEEDMLKQT 833
Cdd:smart00755   1 EANFEYLKNVLLQFLTLRESERETLLPVISTVLQLSPEEMQKLLEV 46
GumC super family cl34566
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
47-244 2.67e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3206:

Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 2.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  47 SSSRDDFSSQIQRRNDQIRKLEAKLSDYAEQLRLmqktkekleIALEKYQDSSMRKLQDQNESFQTNRAKMAEAMSLALE 126
Cdd:COG3206  174 RKALEFLEEQLPELRKELEEAEAALEEFRQKNGL---------VDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAA 244
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 127 KKDQEWMEK-----------LASLEQEKLSLTSRLDEM----TEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQ 191
Cdd:COG3206  245 LRAQLGSGPdalpellqspvIQQLRAQLAELEAELAELsaryTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEA 324
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 229577012 192 LNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDEL 244
Cdd:COG3206  325 LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEA 377
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
160-719 1.69e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.23  E-value: 1.69e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 160 LFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQA 239
Cdd:COG1196  230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 240 QRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERE 319
Cdd:COG1196  310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 320 RILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLV 399
Cdd:COG1196  390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 400 KHKDDSSKAYRERTDAQISDLEQRLADcaekmksLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEE 479
Cdd:COG1196  470 EEAALLEAALAELLEELAEAAARLLLL-------LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEA 542
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 480 ELLAVQRDRETEankyqdNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVS--VEIAKALEETRKQREE 557
Cdd:COG1196  543 ALAAALQNIVVE------DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGaaVDLVASDLREADARYY 616
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 558 LQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVL 637
Cdd:COG1196  617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 638 RQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTL 717
Cdd:COG1196  697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776

                 ..
gi 229577012 718 QK 719
Cdd:COG1196  777 EA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
55-718 1.08e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 1.08e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    55 SQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSsMRKLQDQNESFQTNRAKmAEAMSLALEKKDQEWME 134
Cdd:TIGR02168  267 EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER-LANLERQLEELEAQLEE-LESKLDELAEELAELEE 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   135 KLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKvkhmLLRREEQLNQREKELKLRGEELNTARLTLG 214
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ----LELQIASLNNEIERLEARLERLEDRRERLQ 420
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   215 KTQDKLYELGEEHE--EICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEH 292
Cdd:TIGR02168  421 QEIEELLKKLEEAElkELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN 500
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   293 LQSEHNKLK-LQHEQHK---------NKVAVTEEERERILSDLQEKAASLE-RRLEANFSQDEHLQELLKEKSSL----- 356
Cdd:TIGR02168  501 LEGFSEGVKaLLKNQSGlsgilgvlsELISVDEGYEAAIEAALGGRLQAVVvENLNAAKKAIAFLKQNELGRVTFlplds 580
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   357 --EQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYR------------------------ 410
Cdd:TIGR02168  581 ikGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElakklrpgyrivtldgdlvrpggv 660
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   411 -----ERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQmewsEERERLQQQVSTQRQRGLEKTARLEEELLAVQ 485
Cdd:TIGR02168  661 itggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELR----KELEELEEELEQLRKELEELSRQISALRKDLA 736
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   486 RDRETEANkyqdnlrlLEEEKNSLLRSKGETDSTVESLTAELEQSRAEmssrqtvsveiakaLEETRKQREELQQQVSKM 565
Cdd:TIGR02168  737 RLEAEVEQ--------LEERIAQLSKELTELEAEIEELEERLEEAEEE--------------LAEAEAEIEELEAQIEQL 794
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   566 TESLVKAEQEVSRLsqdlgvkEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREH---NSQLTSLQQEVLRQTQQ 642
Cdd:TIGR02168  795 KEELKALREALDEL-------RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEEL 867
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 229577012   643 LSSYQSRVSDLESEVLSLTAHSHADECEGEQngtvTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQ 718
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEE----LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID 939
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
126-671 3.27e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 3.27e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 126 EKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDElegfqqqelakvkhMLLRREEqlnqREKELKLRGEE 205
Cdd:PRK02224 198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADE--------------VLEEHEE----RREELETLEAE 259
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 206 LNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSE-------KEEAERRVVDLERREQELQQLIQQVSEDFQK 278
Cdd:PRK02224 260 IEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEaglddadAEAVEARREELEDRDEELRDRLEECRVAAQA 339
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 279 AQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERErilsDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQ 358
Cdd:PRK02224 340 HNEEAESLREDADDLEERAEELREEAAELESELEEAREAVE----DRREEIEELEEEIEELRERFGDAPVDLGNAEDFLE 415
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 359 RLEEARGELLQEKTSHTTAVSSLEAQVsRQNASIID---LQTLVKHKDDSSKAYR-ERTDAQISDLEQRLADCAEKMKSL 434
Cdd:PRK02224 416 ELREERDELREREAELEATLRTARERV-EEAEALLEagkCPECGQPVEGSPHVETiEEDRERVEELEAELEDLEEEVEEV 494
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 435 QQQLKdsqmhTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEellavQRDRETEANKYQDNLRLLEEEKNSLLRSKG 514
Cdd:PRK02224 495 EERLE-----RAEDLVEAEDRIERLEERREDLEELIAERRETIEE-----KRERAEELRERAAELEAEAEEKREAAAEAE 564
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 515 ETDSTVESLTAELEQSRAEMSSRqtvsVEIAKALEETRKQREELQQQVSKMTESLvKAEQEVSRLSQD-LGVKEEEVNAL 593
Cdd:PRK02224 565 EEAEEAREEVAELNSKLAELKER----IESLERIRTLLAAIADAEDEIERLREKR-EALAELNDERRErLAEKRERKREL 639
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 594 KEELQAAR-SSLSSLQAECESRRLEAEEKEREHNSQLTSLQQE---VLRQTQQLSSYQSRVSDLESEVLSL-TAHSHADE 668
Cdd:PRK02224 640 EAEFDEARiEEAREDKERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELEELRERREALENRVEALeALYDEAEE 719

                 ...
gi 229577012 669 CEG 671
Cdd:PRK02224 720 LES 722
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
788-833 8.66e-11

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 57.62  E-value: 8.66e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 229577012   788 EINFEYLKHVVLKFMSSREAEAFQLIRAVSVLLHFSKEEEDMLKQT 833
Cdd:smart00755   1 EANFEYLKNVLLQFLTLRESERETLLPVISTVLQLSPEEMQKLLEV 46
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
286-657 1.01e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.44  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   286 LEKSMEHLQSE-HNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQE--------LLKEKSSL 356
Cdd:pfam15921  243 VEDQLEALKSEsQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEqarnqnsmYMRQLSDL 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   357 EQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCA---EKMKS 433
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSlekEQNKR 402
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   434 LQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQrdreteankyqdnlrlleeeknsllrSK 513
Cdd:pfam15921  403 LWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ--------------------------GK 456
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   514 GETDSTVESLTAELEQSRAEMssRQTVSVEIAK--ALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVN 591
Cdd:pfam15921  457 NESLEKVSSLTAQLESTKEML--RKVVEELTAKkmTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ 534
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 229577012   592 ALKEElqaaRSSLSSLQAECESRRLEAEEKERE---HNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEV 657
Cdd:pfam15921  535 HLKNE----GDHLRNVQTECEALKLQMAEKDKVieiLRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEI 599
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
788-830 3.26e-08

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 50.04  E-value: 3.26e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 229577012  788 EINFEYLKHVVLKFMSSREA-EAFQLIRAVSVLLHFSKEEEDML 830
Cdd:pfam01465   1 GANLEYLKNVLLQFLESKESsERKQLLPVIATLLKFSPEEEQKI 44
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
47-244 2.67e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 2.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  47 SSSRDDFSSQIQRRNDQIRKLEAKLSDYAEQLRLmqktkekleIALEKYQDSSMRKLQDQNESFQTNRAKMAEAMSLALE 126
Cdd:COG3206  174 RKALEFLEEQLPELRKELEEAEAALEEFRQKNGL---------VDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAA 244
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 127 KKDQEWMEK-----------LASLEQEKLSLTSRLDEM----TEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQ 191
Cdd:COG3206  245 LRAQLGSGPdalpellqspvIQQLRAQLAELEAELAELsaryTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEA 324
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 229577012 192 LNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDEL 244
Cdd:COG3206  325 LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEA 377
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
446-623 2.36e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.54  E-value: 2.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 446 DKLQMEWSEERERLQQQVSTQRQRGLEKtaRLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKgetdsTVESLTA 525
Cdd:NF033838  53 NESQKEHAKEVESHLEKILSEIQKSLDK--RKHTQNVALNKKLSDIKTEYLYELNVLKEKSEAELTSK-----TKKELDA 125
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 526 ELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARS--S 603
Cdd:NF033838 126 AFEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAKEPRDeeK 205
                        170       180
                 ....*....|....*....|
gi 229577012 604 LSSLQAECESRRLEAEEKER 623
Cdd:NF033838 206 IKQAKAKVESKKAEATRLEK 225
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
160-719 1.69e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.23  E-value: 1.69e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 160 LFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQA 239
Cdd:COG1196  230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 240 QRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERE 319
Cdd:COG1196  310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 320 RILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLV 399
Cdd:COG1196  390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 400 KHKDDSSKAYRERTDAQISDLEQRLADcaekmksLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEE 479
Cdd:COG1196  470 EEAALLEAALAELLEELAEAAARLLLL-------LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEA 542
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 480 ELLAVQRDRETEankyqdNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVS--VEIAKALEETRKQREE 557
Cdd:COG1196  543 ALAAALQNIVVE------DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGaaVDLVASDLREADARYY 616
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 558 LQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVL 637
Cdd:COG1196  617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 638 RQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTL 717
Cdd:COG1196  697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776

                 ..
gi 229577012 718 QK 719
Cdd:COG1196  777 EA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
50-599 5.51e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.31  E-value: 5.51e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  50 RDDFSSQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSMRKLQDQNEsfQTNRAKMAEAMSLALEKKD 129
Cdd:COG1196  234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE--LLAELARLEQDIARLEERR 311
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 130 QEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTA 209
Cdd:COG1196  312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 210 RLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKS 289
Cdd:COG1196  392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 290 MEHLQSEHNKLKLQHEQHKNKVAVTEEERERilSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQ 369
Cdd:COG1196  472 AALLEAALAELLEELAEAAARLLLLLEAEAD--YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 370 EKTSHTTAVSSLEAQVSRQN----ASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHT 445
Cdd:COG1196  550 NIVVEDDEVAAAAIEYLKAAkagrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 446 DKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKyqdnlRLLEEEKNSLLRSKGETDSTVESLTA 525
Cdd:COG1196  630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE-----AELEELAERLAEEELELEEALLAEEE 704
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 229577012 526 ELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQA 599
Cdd:COG1196  705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
55-718 1.08e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 1.08e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    55 SQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSsMRKLQDQNESFQTNRAKmAEAMSLALEKKDQEWME 134
Cdd:TIGR02168  267 EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER-LANLERQLEELEAQLEE-LESKLDELAEELAELEE 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   135 KLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKvkhmLLRREEQLNQREKELKLRGEELNTARLTLG 214
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ----LELQIASLNNEIERLEARLERLEDRRERLQ 420
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   215 KTQDKLYELGEEHE--EICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEH 292
Cdd:TIGR02168  421 QEIEELLKKLEEAElkELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN 500
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   293 LQSEHNKLK-LQHEQHK---------NKVAVTEEERERILSDLQEKAASLE-RRLEANFSQDEHLQELLKEKSSL----- 356
Cdd:TIGR02168  501 LEGFSEGVKaLLKNQSGlsgilgvlsELISVDEGYEAAIEAALGGRLQAVVvENLNAAKKAIAFLKQNELGRVTFlplds 580
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   357 --EQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYR------------------------ 410
Cdd:TIGR02168  581 ikGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElakklrpgyrivtldgdlvrpggv 660
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   411 -----ERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQmewsEERERLQQQVSTQRQRGLEKTARLEEELLAVQ 485
Cdd:TIGR02168  661 itggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELR----KELEELEEELEQLRKELEELSRQISALRKDLA 736
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   486 RDRETEANkyqdnlrlLEEEKNSLLRSKGETDSTVESLTAELEQSRAEmssrqtvsveiakaLEETRKQREELQQQVSKM 565
Cdd:TIGR02168  737 RLEAEVEQ--------LEERIAQLSKELTELEAEIEELEERLEEAEEE--------------LAEAEAEIEELEAQIEQL 794
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   566 TESLVKAEQEVSRLsqdlgvkEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREH---NSQLTSLQQEVLRQTQQ 642
Cdd:TIGR02168  795 KEELKALREALDEL-------RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEEL 867
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 229577012   643 LSSYQSRVSDLESEVLSLTAHSHADECEGEQngtvTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQ 718
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEE----LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID 939
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
125-745 2.21e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.42  E-value: 2.21e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   125 LEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGE 204
Cdd:TIGR02168  216 KELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   205 ELNTARLTLGKTQDKLyelgeehEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAE 284
Cdd:TIGR02168  296 EISRLEQQKQILRERL-------ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE 368
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   285 ALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLE------- 357
Cdd:TIGR02168  369 ELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEleeleee 448
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   358 --------QRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQ--ISDLEQRLAD- 426
Cdd:TIGR02168  449 leelqeelERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQsgLSGILGVLSEl 528
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   427 --CAEKMK---------SLQQQLKDSQMHTDKLQ--MEWSEERERLQQQVSTQRQRGLEKTARL----EEELLAVQRDRE 489
Cdd:TIGR02168  529 isVDEGYEaaieaalggRLQAVVVENLNAAKKAIafLKQNELGRVTFLPLDSIKGTEIQGNDREilknIEGFLGVAKDLV 608
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   490 TEANKYQDNL--------------------RLLEEEKN-------------SLLRSKGETDSTVESLTAELEQSRAEMSS 536
Cdd:TIGR02168  609 KFDPKLRKALsyllggvlvvddldnalelaKKLRPGYRivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEE 688
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   537 RQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECES--- 613
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEElee 768
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   614 RRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEV--LSLTAHSHADECEGEQNGTVTVSD-LDQLQKVNK 690
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtlLNEEAANLRERLESLERRIAATERrLEDLEEQIE 848
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 229577012   691 DLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKErLQDGRQERSAE 745
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL-LRSELEELSEE 902
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
52-737 2.37e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.42  E-value: 2.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    52 DFSSQIQRRNDQIRKLEaklsdyaEQLRLMQKTKEKLEIALEKYQdssmRKLQDQNESFQTNRAKMAEamslaLEKKDQE 131
Cdd:TIGR02168  292 ALANEISRLEQQKQILR-------ERLANLERQLEELEAQLEELE----SKLDELAEELAELEEKLEE-----LKEELES 355
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   132 WMEKLASLEQEKLSLTSRLDEMTEQSLSLfqkRDDLDELEgfqqQELAKVKHMLLRREEQLNQREKELKLRGEELNTARL 211
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQLETL---RSKVAQLE----LQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   212 TLGKTQDKlyelgeeheEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSME 291
Cdd:TIGR02168  429 KLEEAELK---------ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   292 HLQSEHNKLK-LQHEQHK---------NKVAVTEEERERILSDLQEKAASLE-RRLEANFSQDEHLQELLKEKSSL---- 356
Cdd:TIGR02168  500 NLEGFSEGVKaLLKNQSGlsgilgvlsELISVDEGYEAAIEAALGGRLQAVVvENLNAAKKAIAFLKQNELGRVTFlpld 579
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   357 ---EQRLEEARGELLQEKTSHTTAVSSLE-----------------------------AQVSRQNASIIDLQTLVKHKDD 404
Cdd:TIGR02168  580 sikGTEIQGNDREILKNIEGFLGVAKDLVkfdpklrkalsyllggvlvvddldnalelAKKLRPGYRIVTLDGDLVRPGG 659
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   405 SSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQmewsEERERLQQQVSTQRQRGLEKTARLEEELLAV 484
Cdd:TIGR02168  660 VITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELR----KELEELEEELEQLRKELEELSRQISALRKDL 735
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   485 QRdRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSK 564
Cdd:TIGR02168  736 AR-LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   565 MTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECEsrrlEAEEKEREHNSQLTSLQQEVLRQTQQLS 644
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALA 890
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   645 SYQSRVSDLESEVLSLTAHSHADEcegeqngtvtvSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLK 724
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSELR-----------RELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEAL 959
                          730
                   ....*....|...
gi 229577012   725 PDPDSEMKERLQD 737
Cdd:TIGR02168  960 ENKIEDDEEEARR 972
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
124-624 6.47e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.68  E-value: 6.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 124 ALEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRG 203
Cdd:COG1196  243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE 322
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 204 EELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNA 283
Cdd:COG1196  323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 284 EALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEA 363
Cdd:COG1196  403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 364 RGELLQEKTSHTTAVSSLEAQ---------VSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSL 434
Cdd:COG1196  483 LEELAEAAARLLLLLEAEADYegflegvkaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 435 QQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEktARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKG 514
Cdd:COG1196  563 IEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA--VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 515 ETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALK 594
Cdd:COG1196  641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720
                        490       500       510
                 ....*....|....*....|....*....|
gi 229577012 595 EELQAARSSLSSLQAECESRRLEAEEKERE 624
Cdd:COG1196  721 LEEEALEEQLEAEREELLEELLEEEELLEE 750
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
63-765 1.29e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.57  E-value: 1.29e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    63 QIRKLEAKLSDYAEQLRLMQKTKEKLEialeKYQDSSMRKlqdqNESFQTNRAKMAEAMSLALEKKDQEwmekLASLEQE 142
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAE----RYQALLKEK----REYEGYELLKEKEALERQKEAIERQ----LASLEEE 252
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   143 KLSLTSRLDEMTEQSLSLFQKRDDLD-ELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKLY 221
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEELNkKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEID 332
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   222 ELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLK 301
Cdd:TIGR02169  333 KLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   302 LQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQ---EKTSHTTAV 378
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRvekELSKLQREL 492
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   379 SSLEAQVSRQNASIIDLQTLVKHKDDSSK----------------------AYRERTDAQISDLEQRLADCAEKMKSLQ- 435
Cdd:TIGR02169  493 AEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvaqlgsvgeryataievAAGNRLNNVVVEDDAVAKEAIELLKRRKa 572
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   436 --------QQLKDSQMHTDKLQM-----------EWSEERERLQQQV-----------STQRQRGLEKTARLEEELL--- 482
Cdd:TIGR02169  573 gratflplNKMRDERRDLSILSEdgvigfavdlvEFDPKYEPAFKYVfgdtlvvedieAARRLMGKYRMVTLEGELFeks 652
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   483 --------------AVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKAL 548
Cdd:TIGR02169  653 gamtggsraprggiLFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE 732
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   549 EETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHN-S 627
Cdd:TIGR02169  733 EKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIeA 812
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   628 QLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHShADECEGEQNGTVTVSDLDQ----LQKVNKDLEQQLAEKNKTI 703
Cdd:TIGR02169  813 RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI-KSIEKEIENLNGKKEELEEeleeLEAALRDLESRLGDLKKER 891
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 229577012   704 KQLQQRLAELKRTLQkELKLKPDPDSEMKERLQDGRQERSAEKTVLETPMPTAAPSPALGLS 765
Cdd:TIGR02169  892 DELEAQLRELERKIE-ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS 952
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
305-662 4.63e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.65  E-value: 4.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   305 EQHKNKVAVTEEERERILSDLQEKAASLERrLEANFSQDEHLQELLKEKSSLEQRleeargELLQEKTSHTTAVSSLEAQ 384
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLER-LRREREKAERYQALLKEKREYEGY------ELLKEKEALERQKEAIERQ 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   385 VSRQNASIIDLQtlvkhkddsskayrertdAQISDLEQRLADCAEKMKSLQQQLKDsqmhtdklqmEWSEERERLQQQV- 463
Cdd:TIGR02169  246 LASLEEELEKLT------------------EEISELEKRLEEIEQLLEELNKKIKD----------LGEEEQLRVKEKIg 297
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   464 STQRQRglEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVE 543
Cdd:TIGR02169  298 ELEAEI--ASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE 375
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   544 IAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKER 623
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW 455
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 229577012   624 EHNS---QLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTA 662
Cdd:TIGR02169  456 KLEQlaaDLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEA 497
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
155-509 1.61e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 1.61e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   155 EQSLSLFQKRDDLDELEG---FQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEIC 231
Cdd:TIGR02168  667 KTNSSILERRREIEELEEkieELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   232 RTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKlqheqhknkv 311
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN---------- 816
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   312 avteeereRILSDLQEKAASLERRLEAnfsQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNAS 391
Cdd:TIGR02168  817 --------EEAANLRERLESLERRIAA---TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   392 IIDLQTLVKHKDDsskayrerTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHtdklqmewseeRERLQQQVSTQRQRGL 471
Cdd:TIGR02168  886 EEALALLRSELEE--------LSEELRELESKRSELRRELEELREKLAQLELR-----------LEGLEVRIDNLQERLS 946
                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 229577012   472 EKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSL 509
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
126-671 3.27e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 3.27e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 126 EKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDElegfqqqelakvkhMLLRREEqlnqREKELKLRGEE 205
Cdd:PRK02224 198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADE--------------VLEEHEE----RREELETLEAE 259
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 206 LNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSE-------KEEAERRVVDLERREQELQQLIQQVSEDFQK 278
Cdd:PRK02224 260 IEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEaglddadAEAVEARREELEDRDEELRDRLEECRVAAQA 339
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 279 AQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERErilsDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQ 358
Cdd:PRK02224 340 HNEEAESLREDADDLEERAEELREEAAELESELEEAREAVE----DRREEIEELEEEIEELRERFGDAPVDLGNAEDFLE 415
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 359 RLEEARGELLQEKTSHTTAVSSLEAQVsRQNASIID---LQTLVKHKDDSSKAYR-ERTDAQISDLEQRLADCAEKMKSL 434
Cdd:PRK02224 416 ELREERDELREREAELEATLRTARERV-EEAEALLEagkCPECGQPVEGSPHVETiEEDRERVEELEAELEDLEEEVEEV 494
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 435 QQQLKdsqmhTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEellavQRDRETEANKYQDNLRLLEEEKNSLLRSKG 514
Cdd:PRK02224 495 EERLE-----RAEDLVEAEDRIERLEERREDLEELIAERRETIEE-----KRERAEELRERAAELEAEAEEKREAAAEAE 564
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 515 ETDSTVESLTAELEQSRAEMSSRqtvsVEIAKALEETRKQREELQQQVSKMTESLvKAEQEVSRLSQD-LGVKEEEVNAL 593
Cdd:PRK02224 565 EEAEEAREEVAELNSKLAELKER----IESLERIRTLLAAIADAEDEIERLREKR-EALAELNDERRErLAEKRERKREL 639
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 594 KEELQAAR-SSLSSLQAECESRRLEAEEKEREHNSQLTSLQQE---VLRQTQQLSSYQSRVSDLESEVLSL-TAHSHADE 668
Cdd:PRK02224 640 EAEFDEARiEEAREDKERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELEELRERREALENRVEALeALYDEAEE 719

                 ...
gi 229577012 669 CEG 671
Cdd:PRK02224 720 LES 722
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
63-645 5.60e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.71  E-value: 5.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    63 QIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQdSSMRKLQDQNESFQTNRAKMAEAMS-------------LALEKKD 129
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLAKLEAEIDKLL-AEIEELEREIEEERKRRDKLTEEYAelkeeledlraelEEVDKEF 380
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   130 QEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTA 209
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   210 RLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQ----------QVSEDFQKA 279
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvaqlgSVGERYATA 540
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   280 QSNA-------------EALEKSMEHLQSEH---------NKLKLQH----------------------EQHKNKVA--- 312
Cdd:TIGR02169  541 IEVAagnrlnnvvveddAVAKEAIELLKRRKagratflplNKMRDERrdlsilsedgvigfavdlvefdPKYEPAFKyvf 620
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   313 ----VTE--EERERIL---------SDLQEKAASL------ERRLEANF-SQDEHLQELLKEKSSLEQRLEEargeLLQE 370
Cdd:TIGR02169  621 gdtlVVEdiEAARRLMgkyrmvtleGELFEKSGAMtggsraPRGGILFSrSEPAELQRLRERLEGLKRELSS----LQSE 696
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   371 KTSHTTAVSSLEAQVSRQNASIIDLQ---TLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDK 447
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEkeiEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK 776
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   448 LQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAEL 527
Cdd:TIGR02169  777 LEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEI 856
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   528 EQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSL 607
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936
                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 229577012   608 QAEcesrrLEAEEKEREHNSQLTSLQQEVLRQTQQLSS 645
Cdd:TIGR02169  937 EDP-----KGEDEEIPEEELSLEDVQAELQRVEEEIRA 969
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
278-653 4.48e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 4.48e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   278 KAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSS-- 355
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAel 262
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   356 --LEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKhKDDSSKAYRERTDAQISDLEQRLADCAEKMKS 433
Cdd:TIGR02168  263 qeLEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE-RLANLERQLEELEAQLEELESKLDELAEELAE 341
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   434 LQQQLKDSQmhtdklqmewsEERERLQQQvstqrqrgLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLlrsk 513
Cdd:TIGR02168  342 LEEKLEELK-----------EELESLEAE--------LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL---- 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   514 getDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEEtrKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNAL 593
Cdd:TIGR02168  399 ---NNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   594 KEELQAARSSLSSLQAecesrRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDL 653
Cdd:TIGR02168  474 EQALDAAERELAQLQA-----RLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
422-737 5.88e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 5.88e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   422 QRLADCAEKMKSLQQQLKDSQMHTDKLQM-EWSEERERLQQQvstqrqrgLEKTARLEEELLAVQRDRETEANKYQDNLR 500
Cdd:TIGR02168  206 ERQAEKAERYKELKAELRELELALLVLRLeELREELEELQEE--------LKEAEEELEELTAELQELEEKLEELRLEVS 277
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   501 LLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQqqvskmtESLVKAEQEVSRLS 580
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA-------EELAELEEKLEELK 350
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   581 QDLGVKEEEVNALKEELQAARSSLSSLQAECE---SRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEV 657
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLEtlrSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   658 LSLTAHSHADECEGEQNGtvtvsdLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQkELKLKPDPDSEMKERLQD 737
Cdd:TIGR02168  431 EEAELKELQAELEELEEE------LEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEG 503
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
788-833 8.66e-11

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 57.62  E-value: 8.66e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 229577012   788 EINFEYLKHVVLKFMSSREAEAFQLIRAVSVLLHFSKEEEDMLKQT 833
Cdd:smart00755   1 EANFEYLKNVLLQFLTLRESERETLLPVISTVLQLSPEEMQKLLEV 46
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
133-712 1.34e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 65.32  E-value: 1.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  133 MEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEG-----FQQQELAKVKHMLLRREEQLNQREKELKLRGEELN 207
Cdd:COG4913   240 AHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAalrlwFAQRRLELLEAELEELRAELARLEAELERLEARLD 319
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  208 TARLTLGKTQDKLYELGEEHEEicrtnsQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALE 287
Cdd:COG4913   320 ALREELDELEAQIRGNGGDRLE------QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALL 393
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  288 KSMEHLQSEhnklkLQHEQHKNKVAVTEEEREriLSDLQEKAASLERRleaNFSQDEHLQELLKE-KSSLEQRLEEAR-- 364
Cdd:COG4913   394 EALEEELEA-----LEEALAEAEAALRDLRRE--LRELEAEIASLERR---KSNIPARLLALRDAlAEALGLDEAELPfv 463
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  365 GELLQ------------EKTSHTTAVSSL-EAQVSRQNASIID-------LQTLVKHKDDSSKAYRERTDAQISD----- 419
Cdd:COG4913   464 GELIEvrpeeerwrgaiERVLGGFALTLLvPPEHYAAALRWVNrlhlrgrLVYERVRTGLPDPERPRLDPDSLAGkldfk 543
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  420 -------LEQRLAD-----CAEKmkslQQQLKDSQMH-TDKLQMEWSEERERLQQQVSTQRQRGL-----EKTARLEEEL 481
Cdd:COG4913   544 phpfrawLEAELGRrfdyvCVDS----PEELRRHPRAiTRAGQVKGNGTRHEKDDRRRIRSRYVLgfdnrAKLAALEAEL 619
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  482 LAVQRDRETEANKYQDN---LRLLEEEKNSL--LRSKGETDSTVESLTAELEQSRAEMssrqtvsveiaKALEETRKQRE 556
Cdd:COG4913   620 AELEEELAEAEERLEALeaeLDALQERREALqrLAEYSWDEIDVASAEREIAELEAEL-----------ERLDASSDDLA 688
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  557 ELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEV 636
Cdd:COG4913   689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELR 768
                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 229577012  637 LRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQQ-LAEKNKTIKQLQQRLAE 712
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDgLPEYEERFKELLNENSI 845
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
411-723 8.87e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 8.87e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   411 ERTDAQISDLEQRLADCAEKMKSLQQQLKDSQmhtdKLQmEWSEERERLQQQVSTQR-QRGLEKTARLEEELLAVQRDRE 489
Cdd:TIGR02168  182 ERTRENLDRLEDILNELERQLKSLERQAEKAE----RYK-ELKAELRELELALLVLRlEELREELEELQEELKEAEEELE 256
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   490 teanKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESL 569
Cdd:TIGR02168  257 ----ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   570 VKAEQEVSRLSQDLGVKEEEVNALKEELQAARS---SLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSY 646
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAeleELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   647 QSRVSDLESEVLSL-TAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTI--------------KQLQQRLA 711
Cdd:TIGR02168  413 EDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELeeaeqaldaaerelAQLQARLD 492
                          330
                   ....*....|..
gi 229577012   712 ELKRTLQKELKL 723
Cdd:TIGR02168  493 SLERLQENLEGF 504
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
286-657 1.01e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.44  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   286 LEKSMEHLQSE-HNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQE--------LLKEKSSL 356
Cdd:pfam15921  243 VEDQLEALKSEsQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEqarnqnsmYMRQLSDL 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   357 EQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCA---EKMKS 433
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSlekEQNKR 402
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   434 LQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQrdreteankyqdnlrlleeeknsllrSK 513
Cdd:pfam15921  403 LWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ--------------------------GK 456
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   514 GETDSTVESLTAELEQSRAEMssRQTVSVEIAK--ALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVN 591
Cdd:pfam15921  457 NESLEKVSSLTAQLESTKEML--RKVVEELTAKkmTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ 534
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 229577012   592 ALKEElqaaRSSLSSLQAECESRRLEAEEKERE---HNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEV 657
Cdd:pfam15921  535 HLKNE----GDHLRNVQTECEALKLQMAEKDKVieiLRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEI 599
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
199-567 2.74e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 2.74e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   199 LKLRGEELNTARL--TLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQqliqqvsedf 276
Cdd:TIGR02169  660 RAPRGGILFSRSEpaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE---------- 729
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   277 QKAQSNAEALEKSMEHLQSEHNKLkLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQ--DEHLQELLKEKS 354
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLSSLEQEI-ENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPeiQAELSKLEEEVS 808
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   355 SLEQRLEEARGELlqektshtTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSL 434
Cdd:TIGR02169  809 RIEARLREIEQKL--------NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL 880
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   435 QQQLKDSQMHTDKLQMEWSEERERLQQQvSTQRQRGLEKTARLEEELLAVqrdreteankyQDNLRLLEEEKNSLLRSKG 514
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEEL-EAQIEKKRKRLSELKAKLEAL-----------EEELSEIEDPKGEDEEIPE 948
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 229577012   515 ETDStVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTE 567
Cdd:TIGR02169  949 EELS-LEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE 1000
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
50-763 8.94e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 59.36  E-value: 8.94e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    50 RDDFSSQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSMRKLQDQNESFQTNRAKMAEAMSLalekkd 129
Cdd:pfam15921  266 QDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRM------ 339
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   130 qeWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDElegfqqqELAKVKHMLLRREEQLNQREKELKLRGEELNTA 209
Cdd:pfam15921  340 --YEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDD-------QLQKLLADLHKREKELSLEKEQNKRLWDRDTGN 410
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   210 RLTLGKTQDklyELGEEHEEICRTNSQLQAQRDELlseKEEAERRVVDLERREQELQQliqqVSEDFQKAQSNAEALEKS 289
Cdd:pfam15921  411 SITIDHLRR---ELDDRNMEVQRLEALLKAMKSEC---QGQMERQMAAIQGKNESLEK----VSSLTAQLESTKEMLRKV 480
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   290 MEHLQSEHNKLKlQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANF-------SQDEHLQELLKEKSSLEQRLEE 362
Cdd:pfam15921  481 VEELTAKKMTLE-SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLqelqhlkNEGDHLRNVQTECEALKLQMAE 559
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   363 ARG--ELLQEKTSHTTAVSSLEAQVSrqNASIIDLQTLVKHKDDSS------KAYRERTDAQISDLEQRLADCA-EKMKS 433
Cdd:pfam15921  560 KDKviEILRQQIENMTQLVGQHGRTA--GAMQVEKAQLEKEINDRRlelqefKILKDKKDAKIRELEARVSDLElEKVKL 637
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   434 LQQqlkdsqmhtdklqmewSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLlrsk 513
Cdd:pfam15921  638 VNA----------------GSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKL---- 697
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   514 getDSTVESLTAELEQSRAEMSSRQ-------TVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLsqdlgvk 586
Cdd:pfam15921  698 ---KMQLKSAQSELEQTRNTLKSMEgsdghamKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFL------- 767
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   587 EEEVNALKEELQAARSSLSSLQAECESRRleaeEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHA 666
Cdd:pfam15921  768 KEEKNKLSQELSTVATEKNKMAGELEVLR----SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTL 843
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   667 DECEGEQNGTVTVSDLdqlqKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQDGRQERSAEK 746
Cdd:pfam15921  844 DVKELQGPGYTSNSSM----KPRLLQPASFTRTHSNVPSSQSTASFLSHHSRKTNALKEDPTRDLKQLLQELRSVINEEP 919
                          730
                   ....*....|....*..
gi 229577012   747 TVLETPMPTAAPSPALG 763
Cdd:pfam15921  920 TVQLSKAEDKGRAPSLG 936
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
114-750 1.13e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 1.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   114 RAKMAEAMSLALEKKDQEwmEKLASLEQEKLSLTSRLDEMTEQSLSLFQ-KRDDLDELEGFQQQELAK-------VKHML 185
Cdd:pfam02463  155 RLEIEEEAAGSRLKRKKK--EALKKLIEETENLAELIIDLEELKLQELKlKEQAKKALEYYQLKEKLEleeeyllYLDYL 232
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   186 LRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQEL 265
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   266 QQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEH 345
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKL 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   346 LQELLKEKSSLEQR----LEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLqTLVKHKDDSSKAYRERTDAQISDLE 421
Cdd:pfam02463  393 KEEELELKSEEEKEaqllLELARQLEDLLKEEKKEELEILEEEEESIELKQGKL-TEEKEELEKQELKLLKDELELKKSE 471
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   422 QRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERL-------QQQVSTQRQRGLEKTARLEEELLAVQRDRETEANK 494
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLkvllaliKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIV 551
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   495 YQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKAL-------------------------- 548
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLaqldkatleadeddkrakvvegilkd 631
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   549 -------EETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEK 621
Cdd:pfam02463  632 teltklkESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   622 EREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSdldqLQKVNKDLEQQLAEKNK 701
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS----LKEKELAEEREKTEKLK 787
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 229577012   702 TIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQDGRQERSAEKTVLE 750
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELE 836
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
237-712 1.56e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 1.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 237 LQAQRDELLSEKEEAERRvvdlERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEE 316
Cdd:PRK02224 211 LESELAELDEEIERYEEQ----REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRE 286
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 317 ERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARgellqektshtTAVSSLEAQVSRQNASIIDLQ 396
Cdd:PRK02224 287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECR-----------VAAQAHNEEAESLREDADDLE 355
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 397 TLVKHKDDSSKAYR---ERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLqqqvstqrqrglek 473
Cdd:PRK02224 356 ERAEELREEAAELEselEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER-------------- 421
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 474 tARLEEELLAVQRDRETEANKYQDNLRLLEE----------EKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTvSVE 543
Cdd:PRK02224 422 -DELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEE-RLE 499
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 544 IAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSlsslQAECESRRLEAEEKER 623
Cdd:PRK02224 500 RAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREA----AAEAEEEAEEAREEVA 575
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 624 EHNSQLTSLQQEvLRQTQQLSSYQSRVSDLESEVLSLTahshadecegeqngtvtvSDLDQLQKVNKDLEQQLAEKNKTI 703
Cdd:PRK02224 576 ELNSKLAELKER-IESLERIRTLLAAIADAEDEIERLR------------------EKREALAELNDERRERLAEKRERK 636

                 ....*....
gi 229577012 704 KQLQQRLAE 712
Cdd:PRK02224 637 RELEAEFDE 645
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
788-830 3.26e-08

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 50.04  E-value: 3.26e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 229577012  788 EINFEYLKHVVLKFMSSREA-EAFQLIRAVSVLLHFSKEEEDML 830
Cdd:pfam01465   1 GANLEYLKNVLLQFLESKESsERKQLLPVIATLLKFSPEEEQKI 44
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
53-576 4.44e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.95  E-value: 4.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   53 FSSQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEK-----------LEIALEKYQDSSMRKLQDQNE--SFQTNRAKMAE 119
Cdd:TIGR04523 108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKflteikkkekeLEKLNNKYNDLKKQKEELENElnLLEKEKLNIQK 187
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  120 AMSLALEK--KDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLfqkRDDLDELegfqQQELAKVKHMLLRREEQLNQREK 197
Cdd:TIGR04523 188 NIDKIKNKllKLELLLSNLKKKIQKNKSLESQISELKKQNNQL---KDNIEKK----QQEINEKTTEISNTQTQLNQLKD 260
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  198 ELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRD-----ELLSEKEEAERRVVDLERREQELQQLIQQV 272
Cdd:TIGR04523 261 EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQL 340
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  273 SEDFQKaqsnaeaLEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILS---DLQEKAASLERRLEANFSQDEHLQEL 349
Cdd:TIGR04523 341 NEQISQ-------LKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQeikNLESQINDLESKIQNQEKLNQQKDEQ 413
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  350 LKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYR---ERTDAQISDLEQRLAD 426
Cdd:TIGR04523 414 IKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSrsiNKIKQNLEQKQKELKS 493
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  427 CAEKMKSLQQQLKDSQMHTDKLQMEWSEERERlQQQVSTQRQRGLEKTARLEEELLAVQRDR-----ETEANKYQDNLRL 501
Cdd:TIGR04523 494 KEKELKKLNEEKKELEEKVKDLTKKISSLKEK-IEKLESEKKEKESKISDLEDELNKDDFELkkenlEKEIDEKNKEIEE 572
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 229577012  502 LEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEV 576
Cdd:TIGR04523 573 LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEV 647
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
524-747 8.40e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 8.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 524 TAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSS 603
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 604 LSSLQAEcESRRLEAEEKEREHNSQLTSLQQE----VLRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTV 679
Cdd:COG4942   99 LEAQKEE-LAELLRALYRLGRQPPLALLLSPEdfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 229577012 680 SDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQDGRQERSAEKT 747
Cdd:COG4942  178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
187-737 9.82e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 55.95  E-value: 9.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   187 RREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEH---EEICRTNSQLQAQRDE----LLSEKEEAERRVVDLE 259
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKnalQEQLQAETELCAEAEEmrarLAARKQELEEILHELE 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   260 RREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEEReRILSDLQEKaaslerrlean 339
Cdd:pfam01576   82 SRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDI-LLLEDQNSK----------- 149
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   340 fsqdehlqeLLKEKSSLEQRLEEARGELLQEKTShttaVSSLEAQVSRQNASIIDLQTLVKHKDDSskayRERTDAQISD 419
Cdd:pfam01576  150 ---------LSKERKLLEERISEFTSNLAEEEEK----AKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRK 212
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   420 LEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQvSTQRQRGLEKTARLEEELLAVQRDRETEA---NKYQ 496
Cdd:pfam01576  213 LEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEE-TAQKNNALKKIRELEAQISELQEDLESERaarNKAE 291
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   497 DNLRLLEEEKNSLlrsKGETDSTVESLTAELEQSraemSSRQTVSVEIAKALE-ETRKQREELQQQVSKMTESLVKAEQE 575
Cdd:pfam01576  292 KQRRDLGEELEAL---KTELEDTLDTTAAQQELR----SKREQEVTELKKALEeETRSHEAQLQEMRQKHTQALEELTEQ 364
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   576 VSRLSQDLGVKEEEVNALKEELQAARSSLSSLQaeceSRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLES 655
Cdd:pfam01576  365 LEQAKRNKANLEKAKQALESENAELQAELRTLQ----QAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQS 440
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   656 EVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQ-------------QLAEKNKTIKQLQQRLAELKRTLQKELK 722
Cdd:pfam01576  441 ELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEetrqklnlstrlrQLEDERNSLQEQLEEEEEAKRNVERQLS 520
                          570
                   ....*....|....*
gi 229577012   723 LKPDPDSEMKERLQD 737
Cdd:pfam01576  521 TLQAQLSDMKKKLEE 535
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
338-615 1.30e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 1.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 338 ANFSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQvsrqnasiidlqtlvkhkddsskayrertDAQI 417
Cdd:COG4942   14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL-----------------------------ERRI 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 418 SDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQVstqrqRGLEKTARLEEELLAVQRDRETEANKYQD 497
Cdd:COG4942   65 AALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELL-----RALYRLGRQPPLALLLSPEDFLDAVRRLQ 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 498 NLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEmssrqtvsveIAKALEETRKQREELQQQVSkmteslvKAEQEVS 577
Cdd:COG4942  140 YLKYLAPARREQAEELRADLAELAALRAELEAERAE----------LEALLAELEEERAALEALKA-------ERQKLLA 202
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 229577012 578 RLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRR 615
Cdd:COG4942  203 RLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PTZ00121 PTZ00121
MAEBL; Provisional
127-742 1.61e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 1.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  127 KKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLfQKRDDLDELEGFQQQELAKVKHMLLRREEQlnqREKELKLRGEEL 206
Cdd:PTZ00121 1088 RADEATEEAFGKAEEAKKTETGKAEEARKAEEAK-KKAEDARKAEEARKAEDARKAEEARKAEDA---KRVEIARKAEDA 1163
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  207 NTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQ--RDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAE 284
Cdd:PTZ00121 1164 RKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEdaRKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAK 1243
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  285 ALEKsmEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEAR 364
Cdd:PTZ00121 1244 KAEE--ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK 1321
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  365 GellqektshttavsslEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQmh 444
Cdd:PTZ00121 1322 K----------------KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAA-- 1383
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  445 tdKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSL--LRSKGETDSTVES 522
Cdd:PTZ00121 1384 --KKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEAKKAEE 1461
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  523 LTAELEQSRAEMSSRQTV-----SVEIAKALEETRKQREELQQ--QVSKMTESLVKAEQevSRLSQDLGVKEEEVNAlkE 595
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAeeakkADEAKKKAEEAKKKADEAKKaaEAKKKADEAKKAEE--AKKADEAKKAEEAKKA--D 1537
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  596 ELQAARSSLSSLQAECESRRLEAEEKER-EHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQN 674
Cdd:PTZ00121 1538 EAKKAEEKKKADELKKAEELKKAEEKKKaEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE 1617
                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  675 GTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQ--RLAELKRTLQKELKLKPDPDSEMKERLQDGRQER 742
Cdd:PTZ00121 1618 AKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEElkKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
55-599 2.56e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 2.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   55 SQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSmrKLQDQNESFQTNRAKMAEAMSLALEKKDQEWME 134
Cdd:TIGR04523  68 EKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI--KNDKEQKNKLEVELNKLEKQKKENKKNIDKFLT 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  135 KLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRRE------EQLNQREKELKLRGEELNT 208
Cdd:TIGR04523 146 EIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLElllsnlKKKIQKNKSLESQISELKK 225
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  209 ARLTLGKTQDKLY-ELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERreqeLQQLIQQVSEDFQKAQSNAEALE 287
Cdd:TIGR04523 226 QNNQLKDNIEKKQqEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQ----NNKKIKELEKQLNQLKSEISDLN 301
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  288 KSMEhlQSEHNKLKLQHEQHKNKVAVTE---EERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEAR 364
Cdd:TIGR04523 302 NQKE--QDWNKELKSELKNQEKKLEEIQnqiSQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKEN 379
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  365 GELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSS----------KAYRERTDAQISDLEQRLADCAEKMKSL 434
Cdd:TIGR04523 380 QSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKellekeierlKETIIKNNSEIKDLTNQDSVKELIIKNL 459
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  435 QQQLKDSQMHTDKLQMEWSEERERLQQQV-------------STQRQRGLEKTARLEE---ELLAVQRDRETEANKYQDN 498
Cdd:TIGR04523 460 DNTRESLETQLKVLSRSINKIKQNLEQKQkelkskekelkklNEEKKELEEKVKDLTKkisSLKEKIEKLESEKKEKESK 539
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  499 LRLLEEEKNS---------LLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESL 569
Cdd:TIGR04523 540 ISDLEDELNKddfelkkenLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
                         570       580       590
                  ....*....|....*....|....*....|
gi 229577012  570 VKAEQEVSRLSQDLGVKEEEVNALKEELQA 599
Cdd:TIGR04523 620 EKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
54-622 3.90e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.91  E-value: 3.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  54 SSQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEialekyqdssmrKLQDQNESFQTNRAKMAEAMSlALEKKDQEWM 133
Cdd:PRK03918 206 LREINEISSELPELREELEKLEKEVKELEELKEEIE------------ELEKELESLEGSKRKLEEKIR-ELEERIEELK 272
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 134 EKLASLEqEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREkELKLRGEELNTARLTL 213
Cdd:PRK03918 273 KEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE-EKEERLEELKKKLKEL 350
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 214 GKTQDKLYELGEEHEEICRTNSQLQAQRDELLS-EKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEH 292
Cdd:PRK03918 351 EKRLEELEERHELYEEAKAKKEELERLKKRLTGlTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE 430
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 293 LQSEHNKLKLQHEQhknkvaVTEEERERILSDLQEKAASLERRleanfsqdehLQELLKEKSSLEQRLEEARGELLQEKT 372
Cdd:PRK03918 431 LKKAKGKCPVCGRE------LTEEHRKELLEEYTAELKRIEKE----------LKEIEEKERKLRKELRELEKVLKKESE 494
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 373 SHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRE--RTDAQISDLEQRLadcaEKMKSLQQQLKDSQMHTDKLQM 450
Cdd:PRK03918 495 LIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKliKLKGEIKSLKKEL----EKLEELKKKLAELEKKLDELEE 570
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 451 EWSEERERLqqqvstqRQRGLEKTARLEEELlavqRDRETEANKY---QDNLRLLEEEKNSLlrskgetdstvESLTAEL 527
Cdd:PRK03918 571 ELAELLKEL-------EELGFESVEELEERL----KELEPFYNEYlelKDAEKELEREEKEL-----------KKLEEEL 628
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 528 EQSRAEMSsrqtvsvEIAKALEETRKQREELQQQVSKmtESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSL 607
Cdd:PRK03918 629 DKAFEELA-------ETEKRLEELRKELEELEKKYSE--EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699
                        570
                 ....*....|....*
gi 229577012 608 QAECESRRLEAEEKE 622
Cdd:PRK03918 700 KEELEEREKAKKELE 714
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
429-742 4.43e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.91  E-value: 4.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   429 EKMKSLQQQLKDSQMHTDKLQ---MEWSEERERLQQQVStQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEE 505
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEdilNELERQLKSLERQAE-KAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   506 KNSLLRskgETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGV 585
Cdd:TIGR02168  251 AEEELE---ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   586 KEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQevlrQTQQLSSYQSRVSDLESEVLSLTAhsh 665
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE----LEEQLETLRSKVAQLELQIASLNN--- 400
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 229577012   666 adecegeqngtvtvsdldQLQKvnkdLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQDGRQER 742
Cdd:TIGR02168  401 ------------------EIER----LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEE 455
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
150-612 5.13e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 5.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 150 LDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKL--YELGEEH 227
Cdd:COG4717   48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELekLEKLLQL 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 228 EEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKA----QSNAEALEKSMEHLQSEHNKLKLQ 303
Cdd:COG4717  128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELeellEQLSLATEEELQDLAEELEELQQR 207
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 304 HEQHKNKVAVTEEERERILSDLQEKAASLER-RLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLE 382
Cdd:COG4717  208 LAELEEELEEAQEELEELEEELEQLENELEAaALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLA 287
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 383 AQVSRQNASIIDLQTLVKhKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQ 462
Cdd:COG4717  288 LLFLLLAREKASLGKEAE-ELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 463 VSTQRQRGLEKTARLE-----EELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDStvESLTAELEQSRAEMSsr 537
Cdd:COG4717  367 ELEQEIAALLAEAGVEdeeelRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELE-- 442
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 229577012 538 qtvsvEIAKALEETRKQREELQQQVSKMTESlvkaeQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECE 612
Cdd:COG4717  443 -----ELEEELEELREELAELEAELEQLEED-----GELAELLQELEELKAELRELAEEWAALKLALELLEEARE 507
PTZ00121 PTZ00121
MAEBL; Provisional
58-639 6.23e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 6.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   58 QRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSMRKLQDQNESFQTNRAKMAEamslalEKKDQEWMEKLA 137
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE------AKKKADAAKKKA 1387
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  138 SLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQ 217
Cdd:PTZ00121 1388 EEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  218 D--KLYELGEEHEEI-----CRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSM 290
Cdd:PTZ00121 1468 EakKADEAKKKAEEAkkadeAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKK 1547
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  291 EHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLER-RLEANFSQDEhlqELLKEKSSLEQRLEEARGELLQ 369
Cdd:PTZ00121 1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEaRIEEVMKLYE---EEKKMKAEEAKKAEEAKIKAEE 1624
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  370 EKTshttavsslEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQ 449
Cdd:PTZ00121 1625 LKK---------AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK 1695
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  450 MEWSEER--ERLQQQVSTQRQRGLEKTARLEEELLAVQ--RDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTA 525
Cdd:PTZ00121 1696 KEAEEAKkaEELKKKEAEEKKKAEELKKAEEENKIKAEeaKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRK 1775
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  526 ELEQSRAEmssrqtvsvEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDlgVKEEEVNALKEELQAARSSLS 605
Cdd:PTZ00121 1776 EKEAVIEE---------ELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVIND--SKEMEDSAIKEVADSKNMQLE 1844
                         570       580       590
                  ....*....|....*....|....*....|....
gi 229577012  606 SLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQ 639
Cdd:PTZ00121 1845 EADAFEKHKFNKNNENGEDGNKEADFNKEKDLKE 1878
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
57-573 6.62e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.43  E-value: 6.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    57 IQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSMRKLQDQNES----FQTNRAKMAEAMSLALEKKDQEW 132
Cdd:TIGR00618  357 IRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQatidTRTSAFRDLQGQLAHAKKQQELQ 436
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   133 MEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKV---KHMLLRREEQLNQREKELKLRGEELNTA 209
Cdd:TIGR00618  437 QRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQEtrkKAVVLARLLELQEEPCPLCGSCIHPNPA 516
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   210 RLTLG-------KTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVS-----EDFQ 277
Cdd:TIGR00618  517 RQDIDnpgpltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPnlqniTVRL 596
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   278 KAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERilsDLQEKAASLERrLEANFSQDEHLQELLKEKSsLE 357
Cdd:TIGR00618  597 QDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQ---ELALKLTALHA-LQLTLTQERVREHALSIRV-LP 671
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   358 QRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQ 437
Cdd:TIGR00618  672 KELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQ 751
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   438 LKdsqmhtdklqmeWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRS-KGET 516
Cdd:TIGR00618  752 AR------------TVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSdEDIL 819
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   517 DSTVESLTAELEQSRAEMSSRQTVSVEIA---KALEETRKQREELQQQVSKMTESLVKAE 573
Cdd:TIGR00618  820 NLQCETLVQEEEQFLSRLEEKSATLGEIThqlLKYEECSKQLAQLTQEQAKIIQLSDKLN 879
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
459-657 6.78e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 6.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 459 LQQQVSTQRQRGLEKTARLEEELLAVQ---RDRETEANKYQdnlrlleeEKNSLLRSKGETDSTVESLT---AELEQSRA 532
Cdd:COG3206  162 LEQNLELRREEARKALEFLEEQLPELRkelEEAEAALEEFR--------QKNGLVDLSEEAKLLLQQLSeleSQLAEARA 233
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 533 EMSSRQTVSVEIAKALEETRKQREELQQ--QVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSS---- 606
Cdd:COG3206  234 ELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQeaqr 313
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 229577012 607 LQAECESRRLEAEEKEREHNSQLTSLQQEVlrqtQQLSSYQSRVSDLESEV 657
Cdd:COG3206  314 ILASLEAELEALQAREASLQAQLAQLEARL----AELPELEAELRRLEREV 360
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
320-719 1.00e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.46  E-value: 1.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 320 RILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGEL--LQEKTSHTTAVSSLEAQVSRQNASIIDLQT 397
Cdd:COG4717   64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELeeLREELEKLEKLLQLLPLYQELEALEAELAE 143
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 398 LVKHKDDSSKAYRERTDAQiSDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRglEKTARL 477
Cdd:COG4717  144 LPERLEELEERLEELRELE-EELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEE--LEEAQE 220
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 478 EEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRS------KGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEET 551
Cdd:COG4717  221 ELEELEEELEQLENELEAAALEERLKEARLLLLIAaallalLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 552 RKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKERE---HNSQ 628
Cdd:COG4717  301 GKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAallAEAG 380
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 629 LTSLQQ--EVLRQTQQLSSYQSRVSDLESEVLSLtahshadecEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQL 706
Cdd:COG4717  381 VEDEEElrAALEQAEEYQELKEELEELEEQLEEL---------LGELEELLEALDEEELEEELEELEEELEELEEELEEL 451
                        410
                 ....*....|...
gi 229577012 707 QQRLAELKRTLQK 719
Cdd:COG4717  452 REELAELEAELEQ 464
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
51-719 1.20e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 1.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    51 DDFSSQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQ--DSSMRKLQDQNESFQTNRAKMAEaMSLALEKK 128
Cdd:TIGR00618  208 LCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEeqLKKQQLLKQLRARIEELRAQEAV-LEETQERI 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   129 DQ--------EWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDL--DELEGFQQQELAKVKHMLLRREEQLNQREKE 198
Cdd:TIGR00618  287 NRarkaaplaAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHvkQQSSIEEQRRLLQTLHSQEIHIRDAHEVATS 366
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   199 LKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQK 278
Cdd:TIGR00618  367 IREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAA 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   279 AQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQ--EKAASLERRLEANFSQDEHLQELLKEKSSL 356
Cdd:TIGR00618  447 ITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLArlLELQEEPCPLCGSCIHPNPARQDIDNPGPL 526
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   357 EQRLEEargeLLQEKTSHTTAVSSLEAQV----------SRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLAD 426
Cdd:TIGR00618  527 TRRMQR----GEQTYAQLETSEEDVYHQLtserkqraslKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK 602
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   427 CAEKMKSLqqqLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEK 506
Cdd:TIGR00618  603 LSEAEDML---ACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQ 679
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   507 NSLlrskgetdSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKmteslvkaeqevsrLSQDLGVK 586
Cdd:TIGR00618  680 LAL--------QKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSS--------------LGSDLAAR 737
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   587 EEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVlsltaHSHA 666
Cdd:TIGR00618  738 EDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEI-----GQEI 812
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 229577012   667 DECEGEQNGTVtvsdlDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQK 719
Cdd:TIGR00618  813 PSDEDILNLQC-----ETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQ 860
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
471-759 1.25e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 52.33  E-value: 1.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 471 LEKTAR---LEEELLAVQRDRETEANKYQDNLRLLEEEKNSLL------RSKGETDSTVESLTAELEQSRAEMSSRQTVS 541
Cdd:COG3206   96 LERVVDklnLDEDPLGEEASREAAIERLRKNLTVEPVKGSNVIeisytsPDPELAAAVANALAEAYLEQNLELRREEARK 175
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 542 VE--IAKALEETRKQREELQQQVSKMTES--LVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLE 617
Cdd:COG3206  176 ALefLEEQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 618 AEEKERehNSQLTSLQQEVLRQTQQLSSYQSRVSD-------LESEVLSLTAHSHAdecEGEQNGTVTVSDLDQLQKVNK 690
Cdd:COG3206  256 LPELLQ--SPVIQQLRAQLAELEAELAELSARYTPnhpdviaLRAQIAALRAQLQQ---EAQRILASLEAELEALQAREA 330
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 229577012 691 DLEQQLAEKNKTIKQLQQRLAELKRtLQKELKLKPDPDSEMKERLQDGRQERSAEKT---VLETPMPTAAPS 759
Cdd:COG3206  331 SLQAQLAQLEARLAELPELEAELRR-LEREVEVARELYESLLQRLEEARLAEALTVGnvrVIDPAVVPLKPV 401
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
395-606 1.60e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.94  E-value: 1.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 395 LQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMewSEERERLQQQVSTQRQRGLEKT 474
Cdd:COG3206  162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLL--LQQLSELESQLAEARAELAEAE 239
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 475 ARLE--EELLAVQRDRETEAN------KYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSR-QTVSVEIA 545
Cdd:COG3206  240 ARLAalRAQLGSGPDALPELLqspviqQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEaQRILASLE 319
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 229577012 546 KALEETRKQREELQQQVSKMTE---SLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSS 606
Cdd:COG3206  320 AELEALQAREASLQAQLAQLEArlaELPELEAELRRLEREVEVARELYESLLQRLEEARLAEAL 383
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
554-784 1.84e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 50.98  E-value: 1.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 554 QREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQ 633
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 634 Q--------EVLRQTQQLSSYQSRVSDLESEV---LSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKT 702
Cdd:COG3883   97 RsggsvsylDVLLGSESFSDFLDRLSALSKIAdadADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 703 IKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQDGRQERSAEKTVLETPMPTAAPSPALGLSQTPGPITPNTTVTNSSD 782
Cdd:COG3883  177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAG 256

                 ..
gi 229577012 783 IT 784
Cdd:COG3883  257 AA 258
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
286-726 1.89e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 1.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  286 LEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEER---ERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQR--- 359
Cdd:TIGR04523 150 KEKELEKLNNKYNDLKKQKEELENELNLLEKEKlniQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQnnq 229
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  360 LEEARGELLQEKTSHTTAVSSLEAQVSrqnaSIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQlk 439
Cdd:TIGR04523 230 LKDNIEKKQQEINEKTTEISNTQTQLN----QLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ-- 303
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  440 dSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDS- 518
Cdd:TIGR04523 304 -KEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSy 382
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  519 --TVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEE 596
Cdd:TIGR04523 383 kqEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNT 462
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  597 LQAARSSLSSLQAECESRRLEAEEKEREhnsqLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGT 676
Cdd:TIGR04523 463 RESLETQLKVLSRSINKIKQNLEQKQKE----LKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKES 538
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 229577012  677 VTVSDLDQLQKVNKD-----LEQQLAEKNKTIKQLQQRLAELKRTlQKELKLKPD 726
Cdd:TIGR04523 539 KISDLEDELNKDDFElkkenLEKEIDEKNKEIEELKQTQKSLKKK-QEEKQELID 592
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
548-750 3.40e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 3.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 548 LEETRKQREELQQQVSK------MTESLVKAEQEVS-----RLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRL 616
Cdd:COG1196  195 LGELERQLEPLERQAEKaeryreLKEELKELEAELLllklrELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 617 EAEEKEREHNS---QLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAhshadecegeqngtvtvsDLDQLQKVNKDLE 693
Cdd:COG1196  275 ELEELELELEEaqaEEYELLAELARLEQDIARLEERRRELEERLEELEE------------------ELAELEEELEELE 336
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 229577012 694 QQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQDGRQERSAEKTVLE 750
Cdd:COG1196  337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
454-659 3.87e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 3.87e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 454 EERERLQQQVSTQRQRgLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAE 533
Cdd:COG4942   27 AELEQLQQEIAELEKE-LAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 534 ---------MSSRQT-----VSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQA 599
Cdd:COG4942  106 laellralyRLGRQPplallLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 600 ARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLS 659
Cdd:COG4942  186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
547-746 4.38e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 4.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   547 ALEETRKQREELQQQVSKmTESLVKAEQEVSRLSQDLGVKEeeVNALKEELQAARSSLSSLQAECESRRLEAEEKE---R 623
Cdd:TIGR02168  194 ILNELERQLKSLERQAEK-AERYKELKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEeklE 270
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   624 EHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTvtvsDLDQLQKVNKDLEQQLAEKNKTI 703
Cdd:TIGR02168  271 ELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA----QLEELESKLDELAEELAELEEKL 346
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 229577012   704 KQLQQRLAELKRTLQKELKLKPdpdsEMKERLQDGRQERSAEK 746
Cdd:TIGR02168  347 EELKEELESLEAELEELEAELE----ELESRLEELEEQLETLR 385
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
209-575 4.58e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 50.28  E-value: 4.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  209 ARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEK 288
Cdd:pfam07888  29 AELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSA 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  289 SMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELL 368
Cdd:pfam07888 109 SSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELR 188
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  369 QEKTSHTTAVSSLEAQVSrqnasiidlqTLVKHKDDSSKAYRERTDAQISDLEQRLAdcAEKMKSLQQQLKDSQMHTDKL 448
Cdd:pfam07888 189 SLSKEFQELRNSLAQRDT----------QVLQLQDTITTLTQKLTTAHRKEAENEAL--LEELRSLQERLNASERKVEGL 256
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  449 QMEWSE---ERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLta 525
Cdd:pfam07888 257 GEELSSmaaQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERL-- 334
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 229577012  526 eleqsRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQE 575
Cdd:pfam07888 335 -----QEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKE 379
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
189-714 5.78e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 5.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  189 EEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQL 268
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  269 IQQVSEDFQKAQSnaeaLEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERI---LSDLQEKAASLERRLEANFSQDEH 345
Cdd:TIGR04523 203 LSNLKKKIQKNKS----LESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTqtqLNQLKDEQNKIKKQLSEKQKELEQ 278
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  346 LQELLKEKSSLEQRLEEARGELLQEKTSHTTavSSLEAQVSRQNASIIDLQTlvkhkddsskayrertdaQISDLEQRLA 425
Cdd:TIGR04523 279 NNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQN------------------QISQNNKIIS 338
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  426 DCAEKMKSLQQQLKDSQMHTDKLQMEWsEERERLQQQVSTQRQRGLEKTARLE---EELLAVQRDRETEANKYQDNLRLL 502
Cdd:TIGR04523 339 QLNEQISQLKKELTNSESENSEKQREL-EEKQNEIEKLKKENQSYKQEIKNLEsqiNDLESKIQNQEKLNQQKDEQIKKL 417
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  503 EEEKNSLLRSkgetdstVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQD 582
Cdd:TIGR04523 418 QQEKELLEKE-------IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKE 490
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  583 LGVKEEEVNALKEE----------LQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQT--QQLSSYQSRV 650
Cdd:TIGR04523 491 LKSKEKELKKLNEEkkeleekvkdLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENleKEIDEKNKEI 570
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 229577012  651 SDLESEVLSLTA-HSHADEcegeqngtvtvsDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELK 714
Cdd:TIGR04523 571 EELKQTQKSLKKkQEEKQE------------LIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAK 623
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
435-750 1.16e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  435 QQQLKDSQMHTDKLQMEWSE-----ERERLQQQVSTQRQRGLEKTARL--EEELLAVQRDRETEANKYQDNLRLLEEEKN 507
Cdd:pfam17380 288 QQQEKFEKMEQERLRQEKEEkarevERRRKLEEAEKARQAEMDRQAAIyaEQERMAMERERELERIRQEERKRELERIRQ 367
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  508 SLLRSKGETDSTVESLtaELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKmteSLVKAEQEVSRlsqdlgvkE 587
Cdd:pfam17380 368 EEIAMEISRMRELERL--QMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM---EQIRAEQEEAR--------Q 434
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  588 EEVNALKEElqaarsslsslqAECESRRLEAEEKEREHnsqltslQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHAD 667
Cdd:pfam17380 435 REVRRLEEE------------RAREMERVRLEEQERQQ-------QVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRK 495
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  668 --ECEGEQNGTVTVSDLDQLQKVNKDLEQQlaeKNKTIKQLQQRLAELKRTLQKELklkpdpdsEMKERLQDGRQERSAE 745
Cdd:pfam17380 496 ilEKELEERKQAMIEEERKRKLLEKEMEER---QKAIYEEERRREAEEERRKQQEM--------EERRRIQEQMRKATEE 564

                  ....*
gi 229577012  746 KTVLE 750
Cdd:pfam17380 565 RSRLE 569
COG5022 COG5022
Myosin heavy chain [General function prediction only];
485-733 1.45e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.92  E-value: 1.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  485 QRDRETEANKYQD------NLRLLEEEKNSLlrskgETDSTVESLT-AELEQSRAEMSSRQTVSVEIAKALEETRKQREE 557
Cdd:COG5022   812 YRSYLACIIKLQKtikrekKLRETEEVEFSL-----KAEVLIQKFGrSLKAKKRFSLLKKETIYLQSAQRVELAERQLQE 886
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  558 LQQQVSKMTES---LVKAEQEVSRLSQDLGVKEEEVNALKEEL-----QAARSSLSSLQAECESRRLEAEEKEREHNSQL 629
Cdd:COG5022   887 LKIDVKSISSLklvNLELESEIIELKKSLSSDLIENLEFKTELiarlkKLLNNIDLEEGPSIEYVKLPELNKLHEVESKL 966
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  630 TSLQQEVLRQTQQLSSYQSRVSDLESEVLSL--TAHSHADECEGEQNGTVTVsdldqlqkvnKDLEQQLAEKNKTIKQLQ 707
Cdd:COG5022   967 KETSEEYEDLLKKSTILVREGNKANSELKNFkkELAELSKQYGALQESTKQL----------KELPVEVAELQSASKIIS 1036
                         250       260
                  ....*....|....*....|....*.
gi 229577012  708 QRLAELKRtLQKELKLKPDPDSEMKE 733
Cdd:COG5022  1037 SESTELSI-LKPLQKLKGLLLLENNQ 1061
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
546-718 1.55e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  546 KALEETRKQRE------ELQQQVSKMTESLVKAEQEVSRLsqDLGVKEEEVNALKEELQAARSSLSSLQAE---CESRRL 616
Cdd:COG4913   242 EALEDAREQIEllepirELAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEAElerLEARLD 319
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  617 EAEEKEREHNSQ--------LTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKV 688
Cdd:COG4913   320 ALREELDELEAQirgnggdrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEE 399
                         170       180       190
                  ....*....|....*....|....*....|
gi 229577012  689 NKDLEQQLAEKNKTIKQLQQRLAELKRTLQ 718
Cdd:COG4913   400 LEALEEALAEAEAALRDLRRELRELEAEIA 429
mukB PRK04863
chromosome partition protein MukB;
348-736 1.63e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.80  E-value: 1.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  348 ELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYR-----ERTDAQISDLEQ 422
Cdd:PRK04863  283 VHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRqqekiERYQADLEELEE 362
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  423 RLADCAEKMKSLQQQLKDSQMHTDKLQmewsEERERLQQQVSTQRQRglektarleeelLAVQrdrETEANKYQDNLRLL 502
Cdd:PRK04863  363 RLEEQNEVVEEADEQQEENEARAEAAE----EEVDELKSQLADYQQA------------LDVQ---QTRAIQYQQAVQAL 423
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  503 EEEKNSLlrskGETDSTVESLTAELEQSRAE--------------MSSRQTVSVEIAKALEETRK--------------- 553
Cdd:PRK04863  424 ERAKQLC----GLPDLTADNAEDWLEEFQAKeqeateellsleqkLSVAQAAHSQFEQAYQLVRKiagevsrseawdvar 499
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  554 --------------QREELQQQVSKMTESLVKaEQEVSRLSQDLGVK-------EEEVNALKEELQAARSSLSSLQAECE 612
Cdd:PRK04863  500 ellrrlreqrhlaeQLQQLRMRLSELEQRLRQ-QQRAERLLAEFCKRlgknlddEDELEQLQEELEARLESLSESVSEAR 578
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  613 SRRLEaeekEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLEsevlsltahshadECEGEQngTVTVSDLDQLQkvnkdl 692
Cdd:PRK04863  579 ERRMA----LRQQLEQLQARIQRLAARAPAWLAAQDALARLR-------------EQSGEE--FEDSQDVTEYM------ 633
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 229577012  693 eQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQ 736
Cdd:PRK04863  634 -QQLLERERELTVERDELAARKQALDEEIERLSQPGGSEDPRLN 676
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
174-433 1.93e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 1.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 174 QQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEE----HEEICRTNSQLQAQRDELLSEKE 249
Cdd:COG4942   25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQElaalEAELAELEKEIAELRAELEAQKE 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 250 EAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEhlqsehnklklqheqhknkvavteeERERILSDLQEKA 329
Cdd:COG4942  105 ELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP-------------------------ARREQAEELRADL 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 330 ASLERRLEANFSQDEHLQELLKEkssleqrLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQtlvkhkddsskAY 409
Cdd:COG4942  160 AELAALRAELEAERAELEALLAE-------LEEERAALEALKAERQKLLARLEKELAELAAELAELQ-----------QE 221
                        250       260
                 ....*....|....*....|....
gi 229577012 410 RERTDAQISDLEQRLADCAEKMKS 433
Cdd:COG4942  222 AEELEALIARLEAEAAAAAERTPA 245
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
113-724 1.95e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 1.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 113 NRAKMAEAMSLALEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEqL 192
Cdd:PRK03918 193 ELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEE-L 271
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 193 NQREKELKLRGEELNtarltlgktqdKLYELGEEHEEicrtnsqLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQV 272
Cdd:PRK03918 272 KKEIEELEEKVKELK-----------ELKEKAEEYIK-------LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL 333
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 273 SEDfqkaQSNAEALEKSMEHLQSEHNKLKLQHEQHkNKVAVTEEERERILSDLQEKA-ASLERRLEANFSQDEHLQELLK 351
Cdd:PRK03918 334 EEK----EERLEELKKKLKELEKRLEELEERHELY-EEAKAKKEELERLKKRLTGLTpEKLEKELEELEKAKEEIEEEIS 408
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 352 EkssleqrLEEARGELLQEKTSHTTAVSSLEAqvSRQNASIIDLQTLVKHKDDSSKAYRertdAQISDLEQRLADCAEKM 431
Cdd:PRK03918 409 K-------ITARIGELKKEIKELKKAIEELKK--AKGKCPVCGRELTEEHRKELLEEYT----AELKRIEKELKEIEEKE 475
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 432 KSLQQQLKdsqmhtdKLQMEWSEERErlqqqVSTQRQRgLEKTARLEEELlavqrdRETEANKYQDNLRLLEEEKNSLLR 511
Cdd:PRK03918 476 RKLRKELR-------ELEKVLKKESE-----LIKLKEL-AEQLKELEEKL------KKYNLEELEKKAEEYEKLKEKLIK 536
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 512 SKGETDSTVESLT--AELEQSRAEMSSR-QTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLS---QDLGV 585
Cdd:PRK03918 537 LKGEIKSLKKELEklEELKKKLAELEKKlDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKdaeKELER 616
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 586 KEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNsqltslQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHsh 665
Cdd:PRK03918 617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS------EEEYEELREEYLELSRELAGLRAELEELEKR-- 688
                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 229577012 666 adecegeqngtvtvsdLDQLQKVNKDLEQQLAE---KNKTIKQLQQRLAELKRTLQKELKLK 724
Cdd:PRK03918 689 ----------------REEIKKTLEKLKEELEErekAKKELEKLEKALERVEELREKVKKYK 734
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
56-368 2.23e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 2.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    56 QIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQdSSMRKLQDQNESFQTNRAKMAEAMSlALEKKDQEWMEK 135
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS-RKIGEIEKEIEQLEQEEEKLKERLE-ELEEDLSSLEQE 752
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   136 LASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQ-----QQELAKVKHMLLRREEQLNQREKELKLRGEELNTAR 210
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE 832
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   211 LTLGKTQDKLYELGEEHEEICRtnsqlqaQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSM 290
Cdd:TIGR02169  833 KEIQELQEQRIDLKEQIKSIEK-------EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   291 EHLQSEHNKLKLQHEQHKNKVAVTEEE----------------RERILSDLQEKAASLERRLEA----NFSQDEHLQELL 350
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEElseiedpkgedeeipeEELSLEDVQAELQRVEEEIRAlepvNMLAIQEYEEVL 985
                          330       340
                   ....*....|....*....|.
gi 229577012   351 KEKSSLE---QRLEEARGELL 368
Cdd:TIGR02169  986 KRLDELKekrAKLEEERKAIL 1006
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
48-651 3.35e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.91  E-value: 3.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    48 SSRDDFSSQIQRRNDQIRKLEAKLSDYAEQLrlmqktkEKLEIALEKYQDSSMRKL---QDQNESFQTNRAKMAEAMSLA 124
Cdd:pfam12128  294 TLDDQWKEKRDELNGELSAADAAVAKDRSEL-------EALEDQHGAFLDADIETAaadQEQLPSWQSELENLEERLKAL 366
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   125 LEKK---DQEWMEKLASLEQEKLSLTSRLDEMTEQS-----LSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQRE 196
Cdd:pfam12128  367 TGKHqdvTAKYNRRRSKIKEQNNRDIAGIKDKLAKIreardRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRL 446
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   197 KELKLRgeeLNTARLT------LGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQ 270
Cdd:pfam12128  447 GELKLR---LNQATATpelllqLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALD 523
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   271 QVSED-FQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKV--AVTEEERERILS------DLQE----KAASLERRLE 337
Cdd:pfam12128  524 ELELQlFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLdpEVWDGSVGGELNlygvklDLKRidvpEWAASEEELR 603
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   338 ANFSQ-DEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAqvsrqnaSIIDLQTLVKHKDDSSKAYRERTDAQ 416
Cdd:pfam12128  604 ERLDKaEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN-------ARLDLRRLFDEKQSEKDKKNKALAER 676
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   417 ISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQrglEKTARLEEELLA--VQRDRETEAnk 494
Cdd:pfam12128  677 KDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALD---AQLALLKAAIAArrSGAKAELKA-- 751
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   495 yqdnlrlLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSrqtVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQ 574
Cdd:pfam12128  752 -------LETWYKRDLASLGVDPDVIAKLKREIRTLERKIER---IAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIER 821
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   575 EVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAE---------CESRRLeAEEKEREHNSQLTSLQQEVLRQTQQLSS 645
Cdd:pfam12128  822 AISELQQQLARLIADTKLRRAKLEMERKASEKQQVRlsenlrglrCEMSKL-ATLKEDANSEQAQGSIGERLAQLEDLKL 900

                   ....*.
gi 229577012   646 YQSRVS 651
Cdd:pfam12128  901 KRDYLS 906
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
236-720 3.75e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 3.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  236 QLQAQRDELlsekEEAERRVVDLERREQELQQLIQQvSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQH-----EQHKNK 310
Cdd:COG4913   229 ALVEHFDDL----ERAHEALEDAREQIELLEPIREL-AERYAAARERLAELEYLRAALRLWFAQRRLELleaelEELRAE 303
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  311 VAVTEEERERI---LSDLQEKAASLERRLEANFSQDehLQELLKEKSSLEQRLEEARGELLQektsHTTAVSSLEAQVSR 387
Cdd:COG4913   304 LARLEAELERLearLDALREELDELEAQIRGNGGDR--LEQLEREIERLERELEERERRRAR----LEALLAALGLPLPA 377
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  388 QNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADcaekmksLQQQLKdsqmhtdklqmEWSEERERLQQQVSTQR 467
Cdd:COG4913   378 SAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD-------LRRELR-----------ELEAEIASLERRKSNIP 439
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  468 QRGLEKTARLEEEL-------------------------------------LAVQRDRETEANKYQDNLRL--------L 502
Cdd:COG4913   440 ARLLALRDALAEALgldeaelpfvgelievrpeeerwrgaiervlggfaltLLVPPEHYAAALRWVNRLHLrgrlvyerV 519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  503 EEEKNSLLRSKGETDSTVESLTAELEQSRA----EMSSRQTV-SVEIAKALEETRK------------------------ 553
Cdd:COG4913   520 RTGLPDPERPRLDPDSLAGKLDFKPHPFRAwleaELGRRFDYvCVDSPEELRRHPRaitragqvkgngtrhekddrrrir 599
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  554 -----------QREELQQQVSKMTESLVKAEQEVSRLSQ-----------------------DLGVKEEEVNALKEELQA 599
Cdd:COG4913   600 sryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAeldalqerrealqrlaeyswdeiDVASAEREIAELEAELER 679
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  600 ARSSLSSLQA------ECESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVlSLTAHSHADECEGEQ 673
Cdd:COG4913   680 LDASSDDLAAleeqleELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLA-RLELRALLEERFAAA 758
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 229577012  674 NGTvtvsdlDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKE 720
Cdd:COG4913   759 LGD------AVERELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
235-720 3.91e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 3.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 235 SQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVT 314
Cdd:COG4717   49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 315 EEERERilSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVsslEAQVSRQNASIID 394
Cdd:COG4717  129 PLYQEL--EALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLAT---EEELQDLAEELEE 203
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 395 LQtlvkhkddsskAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKT 474
Cdd:COG4717  204 LQ-----------QRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLI 272
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 475 ARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQ 554
Cdd:COG4717  273 LTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQEL 352
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 555 REELQQQVSKMTesLVKAEQEVSRLSQDLGVKEEE----VNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNsqLT 630
Cdd:COG4717  353 LREAEELEEELQ--LEELEQEIAALLAEAGVEDEEelraALEQAEEYQELKEELEELEEQLEELLGELEELLEALD--EE 428
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 631 SLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEqngtvtVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRL 710
Cdd:COG4717  429 ELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE------LAELLQELEELKAELRELAEEWAALKLALELL 502
                        490
                 ....*....|
gi 229577012 711 AELKRTLQKE 720
Cdd:COG4717  503 EEAREEYREE 512
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
151-469 4.15e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.43  E-value: 4.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  151 DEMTEQSLSLFQKRDDLDELEgfQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYE-----LGE 225
Cdd:pfam17380 268 NEFLNQLLHIVQHQKAVSERQ--QQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAeqermAME 345
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  226 EHEEICRTNSQLQAQRDELLSEKEEAER--RVVDLERREQELQQLIQQVSEDFQKAQS----NAEALEKSMEHLQSEHNK 299
Cdd:pfam17380 346 RERELERIRQEERKRELERIRQEEIAMEisRMRELERLQMERQQKNERVRQELEAARKvkilEEERQRKIQQQKVEMEQI 425
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  300 LKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHL--QELLKEKSSLEQRLEEARGELLQEKTSHTTA 377
Cdd:pfam17380 426 RAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERkrKKLELEKEKRDRKRAEEQRRKILEKELEERK 505
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  378 VSSLEAQVSRqnasiidlQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQmEWSEERE 457
Cdd:pfam17380 506 QAMIEEERKR--------KLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLE-AMERERE 576
                         330
                  ....*....|..
gi 229577012  458 RLQQQVSTQRQR 469
Cdd:pfam17380 577 MMRQIVESEKAR 588
PRK11281 PRK11281
mechanosensitive channel MscK;
410-721 4.21e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 4.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  410 RERTDAQISDLEQRLADCAEKMKSLQQQLKD-------------SQMHTDKLQMEWSEER-------------------- 456
Cdd:PRK11281   75 IDRQKEETEQLKQQLAQAPAKLRQAQAELEAlkddndeetretlSTLSLRQLESRLAQTLdqlqnaqndlaeynsqlvsl 154
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  457 ----ERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLeEEKNSLLRSKGETDSTVESLtaeLEQSRA 532
Cdd:PRK11281  155 qtqpERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALL-NAQNDLQRKSLEGNTQLQDL---LQKQRD 230
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  533 EMSSRQTV---------SVEIAKALEETRKQREELQQQ---VSKMTESLVKAEQEVSR-LSQDLGVKEEEVNALKEELQA 599
Cdd:PRK11281  231 YLTARIQRlehqlqllqEAINSKRLTLSEKTVQEAQSQdeaARIQANPLVAQELEINLqLSQRLLKATEKLNTLTQQNLR 310
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  600 ARSSLSSLQaecesrrleaeEKEREHNSQLTSL------------QQEVLRQTQQLSSYQSRVSDLESEVLSLT------ 661
Cdd:PRK11281  311 VKNWLDRLT-----------QSERNIKEQISVLkgslllsrilyqQQQALPSADLIEGLADRIADLRLEQFEINqqrdal 379
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 229577012  662 --AHSHADECEGEQNGTVTVSDLDQLQKV-----------NKDLEQQLAEKNkTIKQLQQRLAELKRTLQKEL 721
Cdd:PRK11281  380 fqPDAYIDKLEAGHKSEVTDEVRDALLQLlderrelldqlNKQLNNQLNLAI-NLQLNQQQLLSVSDSLQSTL 451
46 PHA02562
endonuclease subunit; Provisional
415-632 5.08e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.93  E-value: 5.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 415 AQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTA---RLEEELLAVQRDREte 491
Cdd:PHA02562 174 DKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAeieELTDELLNLVMDIE-- 251
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 492 anKYQDNLRLLEEEKnSLLRSKGETDSTVESL----------TAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQ 561
Cdd:PHA02562 252 --DPSAALNKLNTAA-AKIKSKIEQFQKVIKMyekggvcptcTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEI 328
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 562 VSKMTESLVK------------------------AEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLqaecesrrle 617
Cdd:PHA02562 329 MDEFNEQSKKllelknkistnkqslitlvdkakkVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSEL---------- 398
                        250
                 ....*....|....*
gi 229577012 618 aeEKEREHNSQLTSL 632
Cdd:PHA02562 399 --VKEKYHRGIVTDL 411
PRK09039 PRK09039
peptidoglycan -binding protein;
502-648 5.08e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.50  E-value: 5.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 502 LEEEKNSLLRSkgetdsTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQ 581
Cdd:PRK09039  71 LERQGNQDLQD------SVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQ 144
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 229577012 582 DlgvkeeeVNALKEELQAARSSLSslqaecesrrlEAEEKEREHNSQLTSLQQEV----LRQTQQLSSYQS 648
Cdd:PRK09039 145 Q-------IAALRRQLAALEAALD-----------ASEKRDRESQAKIADLGRRLnvalAQRVQELNRYRS 197
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
161-394 5.54e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 5.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  161 FQKRDDLDELEGfQQQELAKVKHMLLRREEQLNQREKELKLRGEELNT------ARLTLGKTQDKLYELGEEHEEICRTN 234
Cdd:COG4913   606 FDNRAKLAALEA-ELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswDEIDVASAEREIAELEAELERLDASS 684
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  235 S---QLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKV 311
Cdd:COG4913   685 DdlaALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVE 764
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  312 AVTEEERERILSDLQEKAASLERRLEANFSQ---------------DEHLQELLKEKSSLEQ-RLEEARGELLQEKTSHT 375
Cdd:COG4913   765 RELRENLEERIDALRARLNRAEEELERAMRAfnrewpaetadldadLESLPEYLALLDRLEEdGLPEYEERFKELLNENS 844
                         250       260
                  ....*....|....*....|
gi 229577012  376 TA-VSSLEAQVSRQNASIID 394
Cdd:COG4913   845 IEfVADLLSKLRRAIREIKE 864
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
92-753 6.83e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.71  E-value: 6.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    92 LEKYQDSSMRKLQDQNESFQTNRAKMaEAMSLALEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELE 171
Cdd:pfam01576  350 MRQKHTQALEELTEQLEQAKRNKANL-EKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR 428
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   172 GFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEA 251
Cdd:pfam01576  429 AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEE 508
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   252 ERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAAS 331
Cdd:pfam01576  509 EEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVD 588
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   332 L--ERRLEANFS--QDEHLQELLKEKSSLEQRLEE---ARGELLQEKTSHTTAVSSLEA------QVSRQNASI-IDLQT 397
Cdd:pfam01576  589 LdhQRQLVSNLEkkQKKFDQMLAEEKAISARYAEErdrAEAEAREKETRALSLARALEEaleakeELERTNKQLrAEMED 668
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   398 LVKHKDDSSKAYRERTDAQISdLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARL 477
Cdd:pfam01576  669 LVSSKDDVGKNVHELERSKRA-LEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQL 747
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   478 EEELlavqRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREE 557
Cdd:pfam01576  748 VKQV----RELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDE 823
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   558 LQQQVSKMTESLVKAEQEVSRLSQDLGVKEEevnaLKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVL 637
Cdd:pfam01576  824 ILAQSKESEKKLKNLEAELLQLQEDLAASER----ARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELE 899
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   638 RQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGtvtvSDLDQLQKVNKDLEQQLAEKNKTIKQLQQrlAELKRTL 717
Cdd:pfam01576  900 EEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSE----SARQQLERQNKELKAKLQEMEGTVKSKFK--SSIAALE 973
                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 229577012   718 QKELKLKPDPDSEMKERLQDGRQERSAEKTVLETPM 753
Cdd:pfam01576  974 AKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLL 1009
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
134-364 7.14e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 7.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 134 EKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLdelegfqQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTL 213
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKAL-------LKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 214 GKTQDKLYELGEEHEEICRTNSQLQAQ-RDELLSEKEEAERRVVDLERREQELQQLIQQVsEDFQKAQSNAEALEKSMEH 292
Cdd:COG4942   93 AELRAELEAQKEELAELLRALYRLGRQpPLALLLSPEDFLDAVRRLQYLKYLAPARREQA-EELRADLAELAALRAELEA 171
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 229577012 293 LQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKeksSLEQRLEEAR 364
Cdd:COG4942  172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA---RLEAEAAAAA 240
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
246-458 8.35e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 8.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 246 SEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDL 325
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 326 QEKAASLERRLEANF--SQDEHLQELLKEKSSLE--------QRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDL 395
Cdd:COG4942  100 EAQKEELAELLRALYrlGRQPPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 229577012 396 QTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERER 458
Cdd:COG4942  180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
56-469 1.05e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  56 QIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDssmrklqdqnesfqtnraKMAEAMSLALEKKDQEWMEK 135
Cdd:COG4717   72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEE------------------LREELEKLEKLLQLLPLYQE 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 136 LASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEG----FQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARL 211
Cdd:COG4717  134 LEALEAELAELPERLEELEERLEELRELEEELEELEAelaeLQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEE 213
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 212 TLGKTQDKLYELGEEHEEIcrTNSQLQAQRDELLSEKEE---AERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEK 288
Cdd:COG4717  214 ELEEAQEELEELEEELEQL--ENELEAAALEERLKEARLlllIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFL 291
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 289 SMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLE------- 361
Cdd:COG4717  292 LLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQleeleqe 371
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 362 ----------------EARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLqtLVKHKDDSSKAYRERTDAQISDLEQRLA 425
Cdd:COG4717  372 iaallaeagvedeeelRAALEQAEEYQELKEELEELEEQLEELLGELEEL--LEALDEEELEEELEELEEELEELEEELE 449
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....
gi 229577012 426 DCAEKMKSLQQQLKdsQMHTDKLQMEWSEERERLQQQVSTQRQR 469
Cdd:COG4717  450 ELREELAELEAELE--QLEEDGELAELLQELEELKAELRELAEE 491
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
343-721 1.42e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 1.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  343 DEHLQELLkeksSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYR-----ERTDAQI 417
Cdd:COG3096   281 RELSERAL----ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRqqekiERYQEDL 356
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  418 SDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQmewsEERERLQQQVStQRQRGLEktarleeellaVQrdrETEANKYQD 497
Cdd:COG3096   357 EELTERLEEQEEVVEEAAEQLAEAEARLEAAE----EEVDSLKSQLA-DYQQALD-----------VQ---QTRAIQYQQ 417
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  498 NLRLLEEEKNSLlrskGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKAL---EETRKQREELQQQVSKMT-------- 566
Cdd:COG3096   418 AVQALEKARALC----GLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLsvaDAARRQFEKAYELVCKIAgeversqa 493
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  567 ------------------ESLVKAEQEVSRLSQDLGvKEEEVNALKEELQ-------AARSSLSSLQAECESRRLEAEEK 621
Cdd:COG3096   494 wqtarellrryrsqqalaQRLQQLRAQLAELEQRLR-QQQNAERLLEEFCqrigqqlDAAEELEELLAELEAQLEELEEQ 572
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  622 EREHNSQLTSLQQEVLRQTQQLSSYQSRvsdlesEVLSLTAHShADECEGEQNGtVTVSDLDQLQkvnkDLEQQLAEKNK 701
Cdd:COG3096   573 AAEAVEQRSELRQQLEQLRARIKELAAR------APAWLAAQD-ALERLREQSG-EALADSQEVT----AAMQQLLERER 640
                         410       420
                  ....*....|....*....|
gi 229577012  702 TIKQLQQRLAELKRTLQKEL 721
Cdd:COG3096   641 EATVERDELAARKQALESQI 660
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
485-656 1.89e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.82  E-value: 1.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 485 QRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTvsvEIAKALEETRKQREELQQQV-- 562
Cdd:COG3883   18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQA---EIAEAEAEIEERREELGERAra 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 563 ----------------SKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHN 626
Cdd:COG3883   95 lyrsggsvsyldvllgSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174
                        170       180       190
                 ....*....|....*....|....*....|
gi 229577012 627 SQLTSLQQEVLRQTQQLSSYQSRVSDLESE 656
Cdd:COG3883  175 AQQAEQEALLAQLSAEEAAAEAQLAELEAE 204
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
543-750 2.23e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  543 EIAKALEETRKQREELqqqvSKMTESLVKAEQEVSRLsqdlgvkeEEVNALKEELQAARSSLSSLQAECESRRLEAEEKE 622
Cdd:COG4913   222 DTFEAADALVEHFDDL----ERAHEALEDAREQIELL--------EPIRELAERYAAARERLAELEYLRAALRLWFAQRR 289
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  623 REH-NSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAhshadecEGEQNGTvtvSDLDQLQKVNKDLEQQLAEKNK 701
Cdd:COG4913   290 LELlEAELEELRAELARLEAELERLEARLDALREELDELEA-------QIRGNGG---DRLEQLEREIERLERELEERER 359
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 229577012  702 TIKQLQQRLAELK----------RTLQKELKLKPDPDSEMKERLQDGRQERSAEKTVLE 750
Cdd:COG4913   360 RRARLEALLAALGlplpasaeefAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
47-244 2.67e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 2.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  47 SSSRDDFSSQIQRRNDQIRKLEAKLSDYAEQLRLmqktkekleIALEKYQDSSMRKLQDQNESFQTNRAKMAEAMSLALE 126
Cdd:COG3206  174 RKALEFLEEQLPELRKELEEAEAALEEFRQKNGL---------VDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAA 244
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 127 KKDQEWMEK-----------LASLEQEKLSLTSRLDEM----TEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQ 191
Cdd:COG3206  245 LRAQLGSGPdalpellqspvIQQLRAQLAELEAELAELsaryTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEA 324
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 229577012 192 LNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDEL 244
Cdd:COG3206  325 LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEA 377
mukB PRK04863
chromosome partition protein MukB;
309-656 2.79e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 2.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  309 NKVAVTEEERErilsDLQEKAASLERRLEANFSQDEHLQELLKEKSSL------EQRLEEARGELLQEKTSHTTAVSSLE 382
Cdd:PRK04863  786 KRIEQLRAERE----ELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVafeadpEAELRQLNRRRVELERALADHESQEQ 861
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  383 AQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQlkdsQMHTDKLQMEWS------EER 456
Cdd:PRK04863  862 QQRSQLEQAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRFVQQH----GNALAQLEPIVSvlqsdpEQF 937
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  457 ERLQQQV--STQRQRGLEKTARLEEELLAVQrdretEANKYQDNLRLLEEEknsllrskgetDSTVESLTAELEQSRaem 534
Cdd:PRK04863  938 EQLKQDYqqAQQTQRDAKQQAFALTEVVQRR-----AHFSYEDAAEMLAKN-----------SDLNEKLRQRLEQAE--- 998
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  535 ssrqtvsveiakalEETRKQREELQQQVSKMTEslvkAEQEVSRLSQDLGVKEEEVNALKEELQAARSSL-SSLQAECES 613
Cdd:PRK04863  999 --------------QERTRAREQLRQAQAQLAQ----YNQVLASLKSSYDAKRQMLQELKQELQDLGVPAdSGAEERARA 1060
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 229577012  614 RRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESE 656
Cdd:PRK04863 1061 RRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERD 1103
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
116-750 2.83e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 2.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   116 KMAEAMSLALEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDElegfqQQELAKVKHMLLRREEQLNQR 195
Cdd:TIGR00618  201 LRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE-----QLKKQQLLKQLRARIEELRAQ 275
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   196 EKELKLRGEELNTARltlgktqdKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERrvvdlerreqelqqlIQQVSED 275
Cdd:TIGR00618  276 EAVLEETQERINRAR--------KAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAK---------------LLMKRAA 332
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   276 FQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTE---EERERILSdLQEKAASLERRLEANFSQDEHLQELLKE 352
Cdd:TIGR00618  333 HVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCqqhTLTQHIHT-LQQQKTTLTQKLQSLCKELDILQREQAT 411
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   353 KSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDaQISDLEQRLADCAEKMK 432
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQ-QLQTKEQIHLQETRKKA 490
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   433 SLQQQLKDSQMHTDKLQMEWSEERERLQQ----QVSTQR-QRGLEKTARLEEELLAVQRDRETEANKYQDnlrlLEEEKN 507
Cdd:TIGR00618  491 VVLARLLELQEEPCPLCGSCIHPNPARQDidnpGPLTRRmQRGEQTYAQLETSEEDVYHQLTSERKQRAS----LKEQMQ 566
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   508 SLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKA----LEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDL 583
Cdd:TIGR00618  567 EIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAedmlACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLT 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   584 GVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAH 663
Cdd:TIGR00618  647 ALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENA 726
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   664 SHADECEGEQNGTVTVSDLDQLQ-------KVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQ 736
Cdd:TIGR00618  727 SSSLGSDLAAREDALNQSLKELMhqartvlKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806
                          650
                   ....*....|....
gi 229577012   737 DGRQERSAEKTVLE 750
Cdd:TIGR00618  807 EIGQEIPSDEDILN 820
UPF0242 pfam06785
Uncharacterized protein family (UPF0242) N-terminus; This region includes an N-terminal ...
543-657 3.11e-04

Uncharacterized protein family (UPF0242) N-terminus; This region includes an N-terminal transmembrane region and a C-terminal coiled-coil.


Pssm-ID: 429117 [Multi-domain]  Cd Length: 194  Bit Score: 42.89  E-value: 3.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  543 EIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKE 622
Cdd:pfam06785  66 EKSFLEEKEAKLTELDAEGFKILEETLEELQSEEERLEEELSQKEEELRRLTEENQQLQIQLQQISQDFAEFRLESEEQL 145
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 229577012  623 REHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEV 657
Cdd:pfam06785 146 AEKQLLINEYQQTIEEQRSVLEKRQDQIENLESKV 180
PTZ00121 PTZ00121
MAEBL; Provisional
54-419 3.59e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 3.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   54 SSQIQRRNDQIRKLEaKLSDYAEQLRLMQKTKEKLEialEKYQDSSMRKLQDQNESFQTNRAKMAEAMSLALEKKDQEwm 133
Cdd:PTZ00121 1446 ADEAKKKAEEAKKAE-EAKKKAEEAKKADEAKKKAE---EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE-- 1519
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  134 EKLASLEQEKLSLTSRLDEMTE----QSLSLFQKRDDLDELEGFQQQELAKV----KHMLLRREEQLNQREKELKLRGEE 205
Cdd:PTZ00121 1520 EAKKADEAKKAEEAKKADEAKKaeekKKADELKKAEELKKAEEKKKAEEAKKaeedKNMALRKAEEAKKAEEARIEEVMK 1599
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  206 LNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEA 285
Cdd:PTZ00121 1600 LYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  286 LEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEAnfsqdehlQELLKEKSSLEQRLEEAR- 364
Cdd:PTZ00121 1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA--------EEAKKEAEEDKKKAEEAKk 1751
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 229577012  365 GELLQEKTSHTTAVSSLEAQVSRQNASIIdLQTLVKHKDDSSKAYRERTDAQISD 419
Cdd:PTZ00121 1752 DEEEKKKIAHLKKEEEKKAEEIRKEKEAV-IEEELDEEDEKRRMEVDKKIKDIFD 1805
PRK12704 PRK12704
phosphodiesterase; Provisional
527-629 3.71e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 3.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 527 LEQSRAEMSSRQTVSVEIAKalEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSS 606
Cdd:PRK12704  44 LEEAKKEAEAIKKEALLEAK--EEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQ 121
                         90       100
                 ....*....|....*....|...
gi 229577012 607 LQAECESRRLEAEEKEREHNSQL 629
Cdd:PRK12704 122 KQQELEKKEEELEELIEEQLQEL 144
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
40-713 5.05e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 5.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    40 DDFASDGSSSRDDFSSQIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKL-EIALEKYQDSSMRKLQDQNESFQTNRAKMA 118
Cdd:pfam02463  240 DLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELkLLAKEEEELKSELLKLERRKVDDEEKLKES 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   119 EAMSLALEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLlrrEEQLNQREKE 198
Cdd:pfam02463  320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERL---SSAAKLKEEE 396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   199 LKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQK 278
Cdd:pfam02463  397 LELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKE 476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   279 AQsnaeaLEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEK-----------AASLERRLEANFSQDEHLQ 347
Cdd:pfam02463  477 TQ-----LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGgriisahgrlgDLGVAVENYKVAISTAVIV 551
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   348 ELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADC 427
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKD 631
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   428 AEKMKSLQQQL-KDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEK 506
Cdd:pfam02463  632 TELTKLKESAKaKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   507 NSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEV--------SR 578
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREkteklkveEE 791
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   579 LSQDLGVKEEEVNALKEELQAARSSLSSLQAEcESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVL 658
Cdd:pfam02463  792 KEEKLKAQEEELRALEEELKEEAELLEEEQLL-IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 229577012   659 SLTAHSH----ADECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAEL 713
Cdd:pfam02463  871 ELLLKEEeleeQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEI 929
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
96-742 5.05e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.88  E-value: 5.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    96 QDSSMRKLQDQNESFQTNRAKMAEAMSLALEKKDQEWMEK--LASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGF 173
Cdd:TIGR00606  198 QGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSReiVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSR 277
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   174 QQQELAKVKHMLLRREEQLNQREKELK----LRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQ--RDELLSE 247
Cdd:TIGR00606  278 KKQMEKDNSELELKMEKVFQGTDEQLNdlyhNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEqgRLQLQAD 357
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   248 KEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKlqheQHKNKVAVTEEERERILSDLQE 327
Cdd:TIGR00606  358 RHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAA----QLCADLQSKERLKQEQADEIRD 433
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   328 KAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEaqVSRQNASIIDLQTLVKhkddSSK 407
Cdd:TIGR00606  434 EKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELS--KAEKNSLTETLKKEVK----SLQ 507
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   408 AYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQ----MEWSEERERLQQQVSTQRQRGLEKTARLEEELLA 483
Cdd:TIGR00606  508 NEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEqirkIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEIN 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   484 VQRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKAleetRKQREELQQQV- 562
Cdd:TIGR00606  588 QTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKS----SKQRAMLAGATa 663
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   563 --SKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESrRLEAEEKEREHNSQLTSLQQEVL-RQ 639
Cdd:TIGR00606  664 vySQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTES-ELKKKEKRRDEMLGLAPGRQSIIdLK 742
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   640 TQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVN--KDLEQQLAEKNKTIKQLQQRL--AELKR 715
Cdd:TIGR00606  743 EKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTimERFQMELKDVERKIAQQAAKLqgSDLDR 822
                          650       660
                   ....*....|....*....|....*..
gi 229577012   716 TLQKELKLKPDPDSEMKERLQDGRQER 742
Cdd:TIGR00606  823 TVQQVNQEKQEKQHELDTVVSKIELNR 849
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
57-634 5.23e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.88  E-value: 5.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    57 IQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKY----QDSSMRKLQDQNE-SFQTNRAKMAEAMSLALEKKDQE 131
Cdd:TIGR00606  400 IERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLgrtiELKKEILEKKQEElKFVIKELQQLEGSSDRILELDQE 479
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   132 WMEKLASLeqEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKH---------MLLRREEQLNQREKELKLR 202
Cdd:TIGR00606  480 LRKAEREL--SKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHhtttrtqmeMLTKDKMDKDEQIRKIKSR 557
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   203 GEELNTARLTLGKTQDKLYE-LGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEdfqkaQS 281
Cdd:TIGR00606  558 HSDELTSLLGYFPNKKQLEDwLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFD-----VC 632
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   282 NAEALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLE 361
Cdd:TIGR00606  633 GSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLK 712
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   362 EARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTLvKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDS 441
Cdd:TIGR00606  713 STESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPEL-RNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDV 791
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   442 QMhTDKLQMEWSEERERLQQQVSTQRQRGLEKT-ARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKGETD--- 517
Cdd:TIGR00606  792 TI-MERFQMELKDVERKIAQQAAKLQGSDLDRTvQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNelk 870
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   518 STVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEEL 597
Cdd:TIGR00606  871 SEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKV 950
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 229577012   598 QAARSSLSSL----QAECESRRLEAEEKEREHNSQLTSLQQ 634
Cdd:TIGR00606  951 KNIHGYMKDIenkiQDGKDDYLKQKETELNTVNAQLEECEK 991
Filament pfam00038
Intermediate filament protein;
416-657 5.62e-04

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 42.99  E-value: 5.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  416 QISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERERL----QQQVSTQRQRGLEKT---ARLEEELLAVQRDR 488
Cdd:pfam00038   5 QLQELNDRLASYIDKVRFLEQQNKLLETKISELRQKKGAEPSRLyslyEKEIEDLRRQLDTLTverARLQLELDNLRLAA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  489 ETEANKYQDNLRL---LEEEKNSLLR-------SKGETDSTVESLTAELEQSR----AEMS------SRQTVSVEI---- 544
Cdd:pfam00038  85 EDFRQKYEDELNLrtsAENDLVGLRKdldeatlARVDLEAKIESLKEELAFLKknheEEVRelqaqvSDTQVNVEMdaar 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  545 ----AKALEETRKQREELQQQVSKMTESLVKAEQEvsRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEE 620
Cdd:pfam00038 165 kldlTSALAEIRAQYEEIAAKNREEAEEWYQSKLE--ELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKKQKAS 242
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 229577012  621 KERehnsQLTSLQQevlRQTQQLSSYQSRVSDLESEV 657
Cdd:pfam00038 243 LER----QLAETEE---RYELQLADYQELISELEAEL 272
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
272-722 9.36e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.79  E-value: 9.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  272 VSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVavteEERERILSDLQEKAASLERRLEAnfsQDEHLQELLK 351
Cdd:pfam05483 217 LKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKM----KDLTFLLEESRDKANQLEEKTKL---QDENLKELIE 289
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  352 EKSSLEQRLEEARGELLQEKTSHTTavssLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKM 431
Cdd:pfam05483 290 KKDHLTKELEDIKMSLQRSMSTQKA----LEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELL 365
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  432 KSLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLE----KTARLEEELLAvqrDRETEANKYQDNLRLLEEEKN 507
Cdd:pfam05483 366 RTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVEleelKKILAEDEKLL---DEKKQFEKIAEELKGKEQELI 442
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  508 SLLRSKgetDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKE 587
Cdd:pfam05483 443 FLLQAR---EKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQ 519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  588 EEVNALKEELQAARSSLSSLQaecesrrleaeEKEREHNSQLTSLQQEVLRQtqqlssyqsrvsdlESEVLSLTAHSHAD 667
Cdd:pfam05483 520 EDIINCKKQEERMLKQIENLE-----------EKEMNLRDELESVREEFIQK--------------GDEVKCKLDKSEEN 574
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 229577012  668 ECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKELK 722
Cdd:pfam05483 575 ARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENK 629
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
111-312 1.02e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 1.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 111 QTNRAKMAEAMSLALEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREE 190
Cdd:COG4942   18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 191 QLNQREKELK------------------LRGEELNTA--RLTLGKT-----QDKLYELGEEHEEICRTNSQLQAQRDELL 245
Cdd:COG4942   98 ELEAQKEELAellralyrlgrqpplallLSPEDFLDAvrRLQYLKYlaparREQAEELRADLAELAALRAELEAERAELE 177
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 229577012 246 SEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVA 312
Cdd:COG4942  178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
PRK11281 PRK11281
mechanosensitive channel MscK;
432-724 1.09e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  432 KSLQQQLkdsqmhtDKLQ-MEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLL 510
Cdd:PRK11281   39 ADVQAQL-------DALNkQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDND 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  511 RSKGETDST--VESLTAELEQSRAEMSSRQtvsveiaKALEETRKQREELQQQV----SKMTESLVKAEQEVSRLSQDLG 584
Cdd:PRK11281  112 EETRETLSTlsLRQLESRLAQTLDQLQNAQ-------NDLAEYNSQLVSLQTQPeraqAALYANSQRLQQIRNLLKGGKV 184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  585 VKEEEVNALKEELQAarsSLSSLQAECESRRleaeeKEREHNSQLTSLQQ----EVLRQTQQLssyQSRVSDLESEV--- 657
Cdd:PRK11281  185 GGKALRPSQRVLLQA---EQALLNAQNDLQR-----KSLEGNTQLQDLLQkqrdYLTARIQRL---EHQLQLLQEAInsk 253
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 229577012  658 -LSLTahshadecegEQngtvTVSDLDQLQKVNK----DLEQQLAEKNktiKQLQQRL----AELKRTLQKELKLK 724
Cdd:PRK11281  254 rLTLS----------EK----TVQEAQSQDEAARiqanPLVAQELEIN---LQLSQRLlkatEKLNTLTQQNLRVK 312
PRK11637 PRK11637
AmiB activator; Provisional
522-744 1.21e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 42.37  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 522 SLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQvskmtesLVKAEQEVSRLSQDLGVKEEEVNALKEELQAAR 601
Cdd:PRK11637  37 AFSAHASDNRDQLKSIQQDIAAKEKSVRQQQQQRASLLAQ-------LKKQEEAISQASRKLRETQNTLNQLNKQIDELN 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 602 SSLSSLQAECE------SRRLEAEEKEREHNS-QLTSLQQEVLRQTQQLSSY-------QSRVSDLESEVLSLTAHSHAD 667
Cdd:PRK11637 110 ASIAKLEQQQAaqerllAAQLDAAFRQGEHTGlQLILSGEESQRGERILAYFgylnqarQETIAELKQTREELAAQKAEL 189
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 668 ECEGEQNGTVtvsdLDQLQKVNKDLEQQLAEKNKTIKQL-------QQRLAELKrtlQKELKLKpdpDSEMK-ERLQDGR 739
Cdd:PRK11637 190 EEKQSQQKTL----LYEQQAQQQKLEQARNERKKTLTGLesslqkdQQQLSELR---ANESRLR---DSIARaEREAKAR 259

                 ....*
gi 229577012 740 QERSA 744
Cdd:PRK11637 260 AEREA 264
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
63-629 1.26e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    63 QIRKLEAKLSDYAEQLRLMQKTKEKLE--IALEKYQDSSMRKLQDQNESFQTNRAKMAEAMSLALEKKDQEWMEKLASLE 140
Cdd:pfam01576  490 RLRQLEDERNSLQEQLEEEEEAKRNVErqLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYD 569
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   141 QEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQ---QELAKVKHMLLRREEQLNQREKElklrGEELNTARLTLGKtq 217
Cdd:pfam01576  570 KLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKkfdQMLAEEKAISARYAEERDRAEAE----AREKETRALSLAR-- 643
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   218 dKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERrvvdlerreqelqqliqqvsedfqkaqsNAEALEKSMEHLQSEH 297
Cdd:pfam01576  644 -ALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGK----------------------------NVHELERSKRALEQQV 694
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   298 NKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEhlqellKEKSSLEQRLEEARGELLQEKTSHTTA 377
Cdd:pfam01576  695 EEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGE------EKRRQLVKQVRELEAELEDERKQRAQA 768
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   378 VSSleaqvsrQNASIIDLQTLVKHKDDSSKAYRErtdaqisdleqrladCAEKMKSLQQQLKDSQMHTDKLQMewSEERE 457
Cdd:pfam01576  769 VAA-------KKKLELDLKELEAQIDAANKGREE---------------AVKQLKKLQAQMKDLQRELEEARA--SRDEI 824
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   458 RLQQQVSTQRQRGLE-KTARLEEELLAVQRDR---ETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAE 533
Cdd:pfam01576  825 LAQSKESEKKLKNLEaELLQLQEDLAASERARrqaQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSN 904
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   534 MSSrqtvsveIAKALEETRKQREELQQQVSKMTESLVKAE---QEVSRLSQDLGVK-EEEVNALKEELQAARSSLSSLQA 609
Cdd:pfam01576  905 TEL-------LNDRLRKSTLQVEQLTTELAAERSTSQKSEsarQQLERQNKELKAKlQEMEGTVKSKFKSSIAALEAKIA 977
                          570       580
                   ....*....|....*....|
gi 229577012   610 ECEsRRLEAEEKEREHNSQL 629
Cdd:pfam01576  978 QLE-EQLEQESRERQAANKL 996
ATG14 pfam10186
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are ...
502-645 1.79e-03

Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are hydrophilic proteins with a predicted molecular mass of 40.5 kDa, and have a coiled-coil motif at the N terminus region. Yeast cells with mutant Atg14 are defective not only in autophagy but also in sorting of carboxypeptidase Y (CPY), a vacuolar-soluble hydrolase, to the vacuole. Subcellular fractionation indicate that Apg14p and Apg6p are peripherally associated with a membrane structure(s). Apg14p was co-immunoprecipitated with Apg6p, suggesting that they form a stable protein complex. These results imply that Apg6/Vps30p has two distinct functions: in the autophagic process and in the vacuolar protein sorting pathway. Apg14p may be a component specifically required for the function of Apg6/Vps30p through the autophagic pathway. There are 17 auto-phagosomal component proteins which are categorized into six functional units, one of which is the AS-PI3K complex (Vps30/Atg6 and Atg14). The AS-PI3K complex and the Atg2-Atg18 complex are essential for nucleation, and the specific function of the AS-PI3K apparently is to produce phosphatidylinositol 3-phosphate (PtdIns(3)P) at the pre-autophagosomal structure (PAS). The localization of this complex at the PAS is controlled by Atg14. Autophagy mediates the cellular response to nutrient deprivation, protein aggregation, and pathogen invasion in humans, and malfunction of autophagy has been implicated in multiple human diseases including cancer. This effect seems to be mediated through direct interaction of the human Atg14 with Beclin 1 in the human phosphatidylinositol 3-kinase class III complex.


Pssm-ID: 462986 [Multi-domain]  Cd Length: 347  Bit Score: 41.67  E-value: 1.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  502 LEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKaLEETRKQREELQQQVSKMTESLvkaeqevSRLSQ 581
Cdd:pfam10186  21 LYELRVDLARLLSEKDSLKKKVEEALEGKEEGEQLEDNIGNKKLK-LRLLKSEVAISNERLNEIKDKL-------DQLRR 92
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 229577012  582 DLGVKEEEVNALKEELQAARSSLSSLQAECESRRleaeekerehNSQLTSLQQEVLRQTQQLSS 645
Cdd:pfam10186  93 EIAEKKKKIEKLRSSLKQRRSDLESASYQLEERR----------ASQLAKLQNSIKRIKQKWTA 146
COG5022 COG5022
Myosin heavy chain [General function prediction only];
529-734 1.80e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.99  E-value: 1.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  529 QSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVkaeQEVSRLSQdlgvKEEEVNALKEELQAARSSLSSLQ 608
Cdd:COG5022   807 GSRKEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLI---QKFGRSLK----AKKRFSLLKKETIYLQSAQRVEL 879
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  609 AECESRRLEAEEKEREHNSQLTS-LQQEVLRQTQQLSsyqsrvSDLESEVLSLTAHSHADEC--------EGEQNGTVTV 679
Cdd:COG5022   880 AERQLQELKIDVKSISSLKLVNLeLESEIIELKKSLS------SDLIENLEFKTELIARLKKllnnidleEGPSIEYVKL 953
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 229577012  680 SDLDQLQKVNKDLEQQLAEKNKTIK-------QLQQRLAELKRT------LQKELKLKPDPDSEMKER 734
Cdd:COG5022   954 PELNKLHEVESKLKETSEEYEDLLKkstilvrEGNKANSELKNFkkelaeLSKQYGALQESTKQLKEL 1021
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
188-634 1.83e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 1.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  188 REEQLNQREKELKLRGEeLNTARLTLGKTQDKLYELGEEHEEICRTNSQL----QAQRDEL------LSEKEEAERRVVD 257
Cdd:COG3096   277 ANERRELSERALELRRE-LFGARRQLAEEQYRLVEMARELEELSARESDLeqdyQAASDHLnlvqtaLRQQEKIERYQED 355
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  258 LERREQELQQLIQQVSEdfqkAQSNAEALEKSMEHLQSEHNKLKLQ--------HEQHKNKV----AVTEEERERILSDL 325
Cdd:COG3096   356 LEELTERLEEQEEVVEE----AAEQLAEAEARLEAAEEEVDSLKSQladyqqalDVQQTRAIqyqqAVQALEKARALCGL 431
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  326 QE-KAASLERRLEAnfsQDEHLQELLKEKSSLEQRL---EEARGELLQEktshTTAVSSLEAQVSRQNASIIDLQTLVKH 401
Cdd:COG3096   432 PDlTPENAEDYLAA---FRAKEQQATEEVLELEQKLsvaDAARRQFEKA----YELVCKIAGEVERSQAWQTARELLRRY 504
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  402 KDDSSKAYRERT-DAQISDLEQRLAdcaekmkslQQQlkdsqmhtdklqmewseERERLQQQVSTQRQRGLEKTARLEEE 480
Cdd:COG3096   505 RSQQALAQRLQQlRAQLAELEQRLR---------QQQ-----------------NAERLLEEFCQRIGQQLDAAEELEEL 558
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  481 LlavqrdreteankyqdnlrlleeeknsllrskgetdstvesltAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQ 560
Cdd:COG3096   559 L-------------------------------------------AELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIK 595
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 229577012  561 QVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAEcesrRLEAEEKEREHNSQLTSLQQ 634
Cdd:COG3096   596 ELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVE----RDELAARKQALESQIERLSQ 665
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
275-746 2.07e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   275 DFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKN---KVAVTEEERERILSDLQEKAASL-----ERRLEAN---FSQD 343
Cdd:pfam12128  235 GIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSdetLIASRQEERQETSAELNQLLRTLddqwkEKRDELNgelSAAD 314
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   344 EHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLQTlvKHKDDSSKAYR------ERTDAQI 417
Cdd:pfam12128  315 AAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTG--KHQDVTAKYNRrrskikEQNNRDI 392
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   418 SDLEQRLADCAEkmkSLQQQLKDSQMHTDKLQMEWseeRERLQQQVSTQRQRGLEKTARLEEelLAVQRDRETEANKYQD 497
Cdd:pfam12128  393 AGIKDKLAKIRE---ARDRQLAVAEDDLQALESEL---REQLEAGKLEFNEEEYRLKSRLGE--LKLRLNQATATPELLL 464
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   498 NLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAeqevs 577
Cdd:pfam12128  465 QLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHF----- 539
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   578 rLSQDLGVKEEEVNALKEELQAARSSL------SSLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQS--- 648
Cdd:pfam12128  540 -LRKEAPDWEQSIGKVISPELLHRTDLdpevwdGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSare 618
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   649 RVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPD 728
Cdd:pfam12128  619 KQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKH 698
                          490
                   ....*....|....*...
gi 229577012   729 SEMKERLQDGRQERSAEK 746
Cdd:pfam12128  699 QAWLEEQKEQKREARTEK 716
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
446-623 2.36e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.54  E-value: 2.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 446 DKLQMEWSEERERLQQQVSTQRQRGLEKtaRLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLRSKgetdsTVESLTA 525
Cdd:NF033838  53 NESQKEHAKEVESHLEKILSEIQKSLDK--RKHTQNVALNKKLSDIKTEYLYELNVLKEKSEAELTSK-----TKKELDA 125
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 526 ELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARS--S 603
Cdd:NF033838 126 AFEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAKEPRDeeK 205
                        170       180
                 ....*....|....*....|
gi 229577012 604 LSSLQAECESRRLEAEEKER 623
Cdd:NF033838 206 IKQAKAKVESKKAEATRLEK 225
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
273-478 2.42e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 2.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 273 SEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEqhkNKVAVTEEERERILSDLQEKAASLERRLEanfSQDEHLQELLKE 352
Cdd:PRK05771  42 NERLRKLRSLLTKLSEALDKLRSYLPKLNPLRE---EKKKVSVKSLEELIKDVEEELEKIEKEIK---ELEEEISELENE 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 353 KSSLEQRLEEAR------GELLQEKTSHTTAVSSleAQVSRQNASIIDLQT------------------LVKHKDDSSKA 408
Cdd:PRK05771 116 IKELEQEIERLEpwgnfdLDLSLLLGFKYVSVFV--GTVPEDKLEELKLESdvenveyistdkgyvyvvVVVLKELSDEV 193
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 409 YRE---------------RTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEERE-RLQQQVSTQRQRGLE 472
Cdd:PRK05771 194 EEElkklgferleleeegTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEiELERAEALSKFLKTD 273

                 ....*.
gi 229577012 473 KTARLE 478
Cdd:PRK05771 274 KTFAIE 279
PLN02939 PLN02939
transferase, transferring glycosyl groups
405-741 2.58e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.43  E-value: 2.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 405 SSKAYRERTDAQISDLEQRLADCAekmKSLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAV 484
Cdd:PLN02939  60 SSNSKLQSNTDENGQLENTSLRTV---MELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGM 136
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 485 QRDRETeankyqdNLRLLEEEKNSLLRSKGETDSTVESLTAE---LEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQ 561
Cdd:PLN02939 137 IQNAEK-------NILLLNQARLQALEDLEKILTEKEALQGKiniLEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNE 209
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 562 VSKMTESlvkAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECEsrRLEAEEKER--------EHNSQLTSLQ 633
Cdd:PLN02939 210 LLIRGAT---EGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEE--RVFKLEKERslldaslrELESKFIVAQ 284
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 634 QEVLR-QTQQLSSYQSRVSDLESEVLSLTAHShadecegEQNGTVTVSDLDQLQKVNKdLEQQLAEKNktIKQLQQRLAE 712
Cdd:PLN02939 285 EDVSKlSPLQYDCWWEKVENLQDLLDRATNQV-------EKAALVLDQNQDLRDKVDK-LEASLKEAN--VSKFSSYKVE 354
                        330       340
                 ....*....|....*....|....*....
gi 229577012 713 LkrtLQKELKLkpdpdseMKERLQDGRQE 741
Cdd:PLN02939 355 L---LQQKLKL-------LEERLQASDHE 373
46 PHA02562
endonuclease subunit; Provisional
295-513 2.67e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 2.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 295 SEHNKLklqheqHKNKVAVTEEEreriLSDLQEKAASLERRLEanfSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSH 374
Cdd:PHA02562 166 SEMDKL------NKDKIRELNQQ----IQTLDMKIDHIQQQIK---TYNKNIEEQRKKNGENIARKQNKYDELVEEAKTI 232
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 375 TTAVSSLEAQVSRQNASIID----------LQTLVKHKDDS----SKAYRERTDA-----QISDLEQRLADCAEKMKSLQ 435
Cdd:PHA02562 233 KAEIEELTDELLNLVMDIEDpsaalnklntAAAKIKSKIEQfqkvIKMYEKGGVCptctqQISEGPDRITKIKDKLKELQ 312
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 436 QQLKDSQMHTDKLQMEWSEERER------LQQQVSTQRQ-----RGLEKTARLEEELLAVQR-DRETEANKYQDNLRLLE 503
Cdd:PHA02562 313 HSLEKLDTAIDELEEIMDEFNEQskklleLKNKISTNKQslitlVDKAKKVKAAIEELQAEFvDNAEELAKLQDELDKIV 392
                        250
                 ....*....|
gi 229577012 504 EEKNSLLRSK 513
Cdd:PHA02562 393 KTKSELVKEK 402
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
441-736 2.94e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.26  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  441 SQMHTDKLQMEWSEERER--LQQQVSTQRQRGLEKTARLEEELLAVQ--RDRETEAN--------------KYQDNLRLL 502
Cdd:pfam05557  12 SQLQNEKKQMELEHKRARieLEKKASALKRQLDRESDRNQELQKRIRllEKREAEAEealreqaelnrlkkKYLEALNKK 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  503 EEEKNSLLRSKGETDSTVESLTAELEQS----RAEMSSRQTVSVEIAKALEETRK---QREELQQQVSKMTESLVKAEQE 575
Cdd:pfam05557  92 LNEKESQLADAREVISCLKNELSELRRQiqraELELQSTNSELEELQERLDLLKAkasEAEQLRQNLEKQQSSLAEAEQR 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  576 VSRLSQDLGVKEEEvnalKEELQAARSSLSSLQaecesrRLEAE-EKEREHNSQLTSLQQEVLRQTQQLSSYQSR----- 649
Cdd:pfam05557 172 IKELEFEIQSQEQD----SEIVKNSKSELARIP------ELEKElERLREHNKHLNENIENKLLLKEEVEDLKRKleree 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  650 -----VSDLESEVLSLTAHSHADECEGEQNGTVTVSDLD------QLQKVNK-------DLEQQLAEKNKTIKQLQQRLA 711
Cdd:pfam05557 242 kyreeAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDlsrrieQLQQREIvlkeensSLTSSARQLEKARRELEQELA 321
                         330       340
                  ....*....|....*....|....*
gi 229577012  712 ELKRTLQkELKLKPDPDSEMKERLQ 736
Cdd:pfam05557 322 QYLKKIE-DLNKKLKRHKALVRRLQ 345
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
411-709 3.11e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.26  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   411 ERTDAQISDLEQRLADCAEKMKS----LQQQLKDSQMHTDKLQMEWSE--ERERLQQQVSTQRQRGLEKTARLEEELLAV 484
Cdd:pfam15921   81 EEYSHQVKDLQRRLNESNELHEKqkfyLRQSVIDLQTKLQEMQMERDAmaDIRRRESQSQEDLRNQLQNTVHELEAAKCL 160
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   485 QRDRETEANKYQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSR--QTVSVEIAKALEE------------ 550
Cdd:pfam15921  161 KEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMhfRSLGSAISKILREldteisylkgri 240
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   551 --TRKQREELQQQVSKMTESLVKAEQEvsRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKEREHNSQ 628
Cdd:pfam15921  241 fpVEDQLEALKSESQNKIELLLQQHQD--RIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ 318
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   629 LTSLQQEVLRQTQQL----SSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDL---EQQLAEKNK 701
Cdd:pfam15921  319 LSDLESTVSQLRSELreakRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLhkrEKELSLEKE 398

                   ....*...
gi 229577012   702 TIKQLQQR 709
Cdd:pfam15921  399 QNKRLWDR 406
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
322-663 3.20e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 41.35  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  322 LSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSLEAQVSRQNASIIDLqtlvkh 401
Cdd:pfam10174 382 IRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERL------ 455
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  402 KDDSSKAYRERTDaQISDLEQRLADCAEKMKSLQQQLkdsqmhtdklqMEWSEERERLQQQVSTQRQRGLEKTARLEEEL 481
Cdd:pfam10174 456 KEQREREDRERLE-ELESLKKENKDLKEKVSALQPEL-----------TEKESSLIDLKEHASSLASSGLKKDSKLKSLE 523
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  482 LAVQRDREtEANKYQDNLRLLEEEKNSLlRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQ 561
Cdd:pfam10174 524 IAVEQKKE-ECSKLENQLKKAHNAEEAV-RTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKK 601
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  562 VSKMteslvkaEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSlqaecESRRLEAEEKEREHNSQLTSLQQEVLRQTQ 641
Cdd:pfam10174 602 IAEL-------ESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLE-----EARRREDNLADNSQQLQLEELMGALEKTRQ 669
                         330       340
                  ....*....|....*....|..
gi 229577012  642 QLSSYQSRVSDLESEVLSLTAH 663
Cdd:pfam10174 670 ELDATKARLSSTQQSLAEKDGH 691
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
56-737 3.32e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.19  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    56 QIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSMRKLQDQNESFQ-TNRAKMAEAMSL-----ALEKKD 129
Cdd:TIGR00606  256 EIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQrTVREKERELVDCqreleKLNKER 335
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   130 QEWMEKLASLEQEKLSLTSRLDEMTEQSL---SLFQKRDDLDELEGFQQQELAKVK----HMLLRR--EEQLNQREKELK 200
Cdd:TIGR00606  336 RLLNQEKTELLVEQGRLQLQADRHQEHIRardSLIQSLATRLELDGFERGPFSERQiknfHTLVIErqEDEAKTAAQLCA 415
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   201 LRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQ 280
Cdd:TIGR00606  416 DLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSL 495
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   281 SNA-EALEKSMEHLQSEHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKE---KSSL 356
Cdd:TIGR00606  496 TETlKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpnKKQL 575
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   357 EQRLEEARGELLQekTSHTTAVSSLEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQ 436
Cdd:TIGR00606  576 EDWLHSKSKEINQ--TRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSK 653
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   437 QLKDSQMHTDkLQMEWSEERERLQQQVSTQRQRGLEKTARLEEellaVQRDRETEANKYQDNLRLLEEEKNSLLRSKGET 516
Cdd:TIGR00606  654 QRAMLAGATA-VYSQFITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEM 728
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   517 DSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVskmtESLVKAEQEVSRLSQDLGVKEEEVNALKE- 595
Cdd:TIGR00606  729 LGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL----GTIMPEEESAKVCLTDVTIMERFQMELKDv 804
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   596 ----ELQAARSSLSSLQAECESRRLEAEEKEREHN---SQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHADE 668
Cdd:TIGR00606  805 erkiAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDtvvSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ 884
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 229577012   669 CEGEQNGTVtVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQD 737
Cdd:TIGR00606  885 QFEEQLVEL-STEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKN 952
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
125-708 3.93e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 40.88  E-value: 3.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  125 LEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQ---QELAKVKHMLLRREEQLNQREKELKL 201
Cdd:pfam05557  18 KKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEealREQAELNRLKKKYLEALNKKLNEKES 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  202 RGEELNTARLTLGKtqdklyELGEEHEEICRTNSQLQAQRdellSEKEEAERRVVDLERREQELQQLIqqvsEDFQKAQS 281
Cdd:pfam05557  98 QLADAREVISCLKN------ELSELRRQIQRAELELQSTN----SELEELQERLDLLKAKASEAEQLR----QNLEKQQS 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  282 NAEALEKSMEHLQSEHNklklQHEQHKNKVAVTEEERERIlsdlqekaASLERRLEANFSQDEHLQELLKEKSSLEQRLE 361
Cdd:pfam05557 164 SLAEAEQRIKELEFEIQ----SQEQDSEIVKNSKSELARI--------PELEKELERLREHNKHLNENIENKLLLKEEVE 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  362 EARGELLQEKTSHTTAVSsLEAQVSRQNAsiiDLQTLVKHKDDSSKAYRERTDA--QISDLEQRLADCAEKMKSLQQQLK 439
Cdd:pfam05557 232 DLKRKLEREEKYREEAAT-LELEKEKLEQ---ELQSWVKLAQDTGLNLRSPEDLsrRIEQLQQREIVLKEENSSLTSSAR 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  440 dsqmHTDKLQMEwseererLQQQVSTQRQRGLEKTARLEEEllavqrdrETEANKYQDNLRLLEEEKNSLlrskgetDST 519
Cdd:pfam05557 308 ----QLEKARRE-------LEQELAQYLKKIEDLNKKLKRH--------KALVRRLQRRVLLLTKERDGY-------RAI 361
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  520 VESLTAELEQSRAemssrqtvSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQA 599
Cdd:pfam05557 362 LESYDKELTMSNY--------SPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESL 433
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  600 ARSSLS-----SLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSS--------------YQSRVSDLE---SEV 657
Cdd:pfam05557 434 ADPSYSkeevdSLRRKLETLELERQRLREQKNELEMELERRCLQGDYDPKKtkvlhlsmnpaaeaYQQRKNQLEklqAEI 513
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 229577012  658 LSLTAHSHADECEGEQNGTVTVSDLDQLQKVNKDLEQQLAEKNKTIKQLQQ 708
Cdd:pfam05557 514 ERLKRLLKKLEDDLEQVLRLPETTSTMNFKEVLDLRKELESAELKNQRLKE 564
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
514-745 4.38e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.82  E-value: 4.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   514 GETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQRE------------------ELQQQVSKMTESLVKAEQE 575
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREkaeryqallkekreyegyELLKEKEALERQKEAIERQ 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   576 VSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESrrlEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLES 655
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKD---LGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE 322
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   656 EVLSLTAHSHADECE--------GEQNGTVT--VSDLDQLQKVNKDLEQQLAEKNKTIKQLQQRLAELKRTLQKeLKLKP 725
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEieelereiEEERKRRDklTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK-LKREI 401
                          250       260
                   ....*....|....*....|
gi 229577012   726 DPDSEMKERLQDGRQERSAE 745
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEE 421
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
66-666 4.45e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 40.93  E-value: 4.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    66 KLEAKLSDYAEQLRLMQKTKEKLEiALEKYQDSSMRKLQDQNESFQTnrakMAEAMSLALEKKDQEWMEKLASLEQEKLS 145
Cdd:pfam01576  184 KHEAMISDLEERLKKEEKGRQELE-KAKRKLEGESTDLQEQIAELQA----QIAELRAQLAKKEEELQAALARLEEETAQ 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   146 LTSRLDEMTEQSLSLFQKRDDLdELEGFQQQELAKVKHMLlrrEEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGE 225
Cdd:pfam01576  259 KNNALKKIRELEAQISELQEDL-ESERAARNKAEKQRRDL---GEELEALKTELEDTLDTTAAQQELRSKREQEVTELKK 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   226 EHEEICRTN-SQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSmeHLQSEHNKLKLQH 304
Cdd:pfam01576  335 ALEEETRSHeAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQA--KQDSEHKRKKLEG 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   305 EQHKNKVAVTEEERERilSDLQEKAASLERRLEANFSQDEHLQ----ELLKEKSSLEQRLEEARgELLQEKTSHTTAVSS 380
Cdd:pfam01576  413 QLQELQARLSESERQR--AELAEKLSKLQSELESVSSLLNEAEgkniKLSKDVSSLESQLQDTQ-ELLQEETRQKLNLST 489
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   381 LEAQVSRQNASIIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEWSEE----- 455
Cdd:pfam01576  490 RLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKaaayd 569
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   456 -----RERLQQQ-----VSTQRQR----GLEKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKN----SLLRSKGETD 517
Cdd:pfam01576  570 klektKNRLQQElddllVDLDHQRqlvsNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKEtralSLARALEEAL 649
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   518 STVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQQQVSKMTESLVKAEQEvsrlsqdLGVKEEEVNALKEEL 597
Cdd:pfam01576  650 EAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDE-------LQATEDAKLRLEVNM 722
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 229577012   598 QAARsslSSLQAECESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHA 666
Cdd:pfam01576  723 QALK---AQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDA 788
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
382-629 4.61e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.49  E-value: 4.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  382 EAQVSRQNAsiIDLQTLVKHKDDSSKAYRERTDAQISDLEQRLADcaEKMKSLQQQLKDSQMHT-DKLQMEWSEERERLQ 460
Cdd:pfam17380 320 EAEKARQAE--MDRQAAIYAEQERMAMERERELERIRQEERKREL--ERIRQEEIAMEISRMRElERLQMERQQKNERVR 395
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  461 QQVSTQRQRGL---EKTARLEEELLAVQRDRETEANKYQDNLRLLEEEKNSLLR----SKGETDSTVESLTAELEQSR-- 531
Cdd:pfam17380 396 QELEAARKVKIleeERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMErvrlEEQERQQQVERLRQQEEERKrk 475
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  532 -----AEMSSRQTVSVEIAKALE---ETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSS 603
Cdd:pfam17380 476 kleleKEKRDRKRAEEQRRKILEkelEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQ 555
                         250       260
                  ....*....|....*....|....*.
gi 229577012  604 LSSLQAECESRRLEAEEKEREHNSQL 629
Cdd:pfam17380 556 EQMRKATEERSRLEAMEREREMMRQI 581
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
56-370 4.71e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 40.73  E-value: 4.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012    56 QIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSMRKLQDQNESFQTNRAKMAEAMSLALEKKDQEWMEK 135
Cdd:pfam02463  699 LEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAE 778
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   136 LASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKlrgEELNTARLTLGK 215
Cdd:pfam02463  779 EREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK---EEQKLEKLAEEE 855
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012   216 TQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMEHLQS 295
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 229577012   296 EHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQDEHLQELLKEKSSLEQRLEEARGELLQE 370
Cdd:pfam02463  936 EPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRA 1010
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
309-657 4.90e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 40.71  E-value: 4.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  309 NKVAVTEEERERILSDLQEKAASLER--RLEANFSQ--------------DEHLQELLKEKSSLEQRLEEARGELLQekt 372
Cdd:COG3096   785 KRLEELRAERDELAEQYAKASFDVQKlqRLHQAFSQfvgghlavafapdpEAELAALRQRRSELERELAQHRAQEQQ--- 861
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  373 sHTTAVSSLEAQVSRQNAsiidLQTLVKHKDDSSKAYRertdaqISDLEQRLADCAEKMKSLQQQLKDSQMHTDKLQMEW 452
Cdd:COG3096   862 -LRQQLDQLKEQLQLLNK----LLPQANLLADETLADR------LEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQ 930
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  453 S--EERERLQQQVST--QRQRGLEKTARLEEELlaVQRdreTEANKYQDNLRLLeeeknsllrskGETDSTVESLTAELE 528
Cdd:COG3096   931 SdpEQFEQLQADYLQakEQQRRLKQQIFALSEV--VQR---RPHFSYEDAVGLL-----------GENSDLNEKLRARLE 994
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  529 QsraemssrqtvsveiakALEETRKQREELQQQVSKMTEslvkAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQ 608
Cdd:COG3096   995 Q-----------------AEEARREAREQLRQAQAQYSQ----YNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEA 1053
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 229577012  609 AEC-ESRRLEAEEKEREHNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEV 657
Cdd:COG3096  1054 EERaRIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDY 1103
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
56-229 5.47e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.13  E-value: 5.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  56 QIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSMRKLQDQNESFQTNRAKM-AEAMSLALEKKDQEWME 134
Cdd:COG4942   63 RIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALlLSPEDFLDAVRRLQYLK 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 135 KLASLEQEKL-SLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHMLLRREEQLNQREKELKLRGEELNTARLTL 213
Cdd:COG4942  143 YLAPARREQAeELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEA 222
                        170
                 ....*....|....*.
gi 229577012 214 GKTQDKLYELGEEHEE 229
Cdd:COG4942  223 EELEALIARLEAEAAA 238
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
189-394 7.25e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.00  E-value: 7.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 189 EEQLNQREKELKLRGEELNTARltlgkTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEEAERRVVDLERREQELQQL 268
Cdd:COG3206  181 EEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012 269 IQQVSED--FQKAQSNAEALEKSMEHLQS----EHNKLKLQHEQHKNKVAVTEEERERILSDLQEKAASLERRLEANFSQ 342
Cdd:COG3206  256 LPELLQSpvIQQLRAQLAELEAELAELSArytpNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQ 335
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 229577012 343 DEHLQELLKEKSSLEQRLEEARGELLQEKTSHTTAVSSL-EAQVSRQ----NASIID 394
Cdd:COG3206  336 LAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLeEARLAEAltvgNVRVID 392
mukB PRK04863
chromosome partition protein MukB;
252-620 7.79e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 39.94  E-value: 7.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  252 ERRVVDLERREQELQQLIQQVSEDFQKAQSNAEALEKSMehlqSEHNKLKLQH--EQHKNKVAVTEEERERILSDLQEKA 329
Cdd:PRK04863  785 EKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFI----GSHLAVAFEAdpEAELRQLNRRRVELERALADHESQE 860
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  330 ASLERRLEANFSQDEHLQELLKEKS-----SLEQRLEEARGELLQEK------TSHTTAVSSLEAQVS--RQNASIIDLq 396
Cdd:PRK04863  861 QQQRSQLEQAKEGLSALNRLLPRLNlladeTLADRVEEIREQLDEAEeakrfvQQHGNALAQLEPIVSvlQSDPEQFEQ- 939
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  397 tlVKHKDDSSKAYRERTDAQI---------------SDLEQRLADCAEKMKSLQQQLKDSQmhtdklqmewsEERERLQQ 461
Cdd:PRK04863  940 --LKQDYQQAQQTQRDAKQQAfaltevvqrrahfsyEDAAEMLAKNSDLNEKLRQRLEQAE-----------QERTRARE 1006
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577012  462 QVSTQRQRGLEKTArleeellaVQRDRETEANKYQDNLRLLEEEKNSLlrskgetdsTVESLTAELEQSRAEMSsrqtvs 541
Cdd:PRK04863 1007 QLRQAQAQLAQYNQ--------VLASLKSSYDAKRQMLQELKQELQDL---------GVPADSGAEERARARRD------ 1063
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 229577012  542 vEIAKALEETRKQREELQQQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAEcesRRLEAEE 620
Cdd:PRK04863 1064 -ELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVE---RRLHRRE 1138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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