|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
3-345 |
3.23e-48 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 165.05 E-value: 3.23e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 3 LWVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGagvEKLRiehqsittpskkkl 82
Cdd:PRK00440 6 IWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYG---EDWR-------------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 83 eintiasNYHLEVNPSDAGNSDrvVIQELIKTVAQSQQIQSSaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLI 162
Cdd:PRK00440 69 -------ENFLELNASDERGID--VIRNKIKEFARTAPVGGA---PFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFI 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 163 LCCNSTSKVIAPIRSRCLAVRV-PLPSvEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALlmceacRVQQYPFS 241
Cdd:PRK00440 137 LSCNYSSKIIDPIQSRCAVFRFsPLKK-EAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAI------NALQAAAA 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 242 PDQDIPEtdwevylrETANAIVSQQSPQ------------RLLEVRARLYELLT-HCISPEVIMKGLVTELLS-NCDGHL 307
Cdd:PRK00440 210 TGKEVTE--------EAVYKITGTARPEeiremielalngDFTEAREKLRDLMIdYGLSGEDIIKQIHREVWSlDIPEEL 281
|
330 340 350
....*....|....*....|....*....|....*...
gi 41393079 308 KAEVAQMAAYYEHRLQLGNKAIYHLEAFVAKFMAIYKK 345
Cdd:PRK00440 282 KVELIDAIGEADFRITEGANERIQLEALLAKLALLGKK 319
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
19-342 |
5.11e-34 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 127.01 E-value: 5.11e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 19 HKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKTRIMCLLRELYGagveklrieHQSITTPSKKKLEINTIASNYH---LE 94
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLC---------ENPEGGKACGQCHSRLMAAGNHpdlLE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 95 VNPSDAGNSDRV-VIQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIA 173
Cdd:COG0470 72 LNPEEKSDQIGIdQIRELGEFLSLTPLEG-----GRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLP 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 174 PIRSRCLAVRVPLPSVEEVCSVLsgvcRKEGllLPPELAKQIAEKSGRNLRKALLMCEAcrvqqypfspdqdipetdWEV 253
Cdd:COG0470 147 TIRSRCQVIRFRPPSEEEALAWL----REEG--VDEDALEAILRLAGGDPRAAINLLQA------------------LAG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 254 Y--LRETANAIVSQQSPQRLLEV--RARLYELLthcispEVIMKGLVTELLSNCDGHLKAEVAQMAAYYEHRLQLG-NKA 328
Cdd:COG0470 203 RkeLLEDLAALLSRDRALELLDAllKAEALELL------DWLLKWLLDNLPLEYAGEDLARAYEALSEADRRLGRYaNDR 276
|
330
....*....|....
gi 41393079 329 IyHLEAFVAKFMAI 342
Cdd:COG0470 277 L-LLEALLAKLGRL 289
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
21-179 |
7.44e-08 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 50.99 E-value: 7.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 21 EQANQLKNLVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGAGVEklriehqsittpskkkleintiasnyHLEVNPSDA 100
Cdd:cd00009 5 EAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAP--------------------------FLYLNASDL 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 101 GNSDrvVIQELIKTVAQSQQIQSSAQREFKVVLLTEVDRLTKDAQHALRRTMEKYM------ATCRLILCCNSTS--KVI 172
Cdd:cd00009 59 LEGL--VVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNdlridrENVRVIGATNRPLlgDLD 136
|
....*..
gi 41393079 173 APIRSRC 179
Cdd:cd00009 137 RALYDRL 143
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
18-185 |
1.35e-05 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 44.89 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 18 YHKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKTRIMCLLRELYGagveklriEHQSITTPSKKKLEINTIASNYHLEVN 96
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFC--------EEPGDDLPCGQCRSCRRIESGNHPDLV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 97 P-SDAGNSDRV-VIQELIKTVAQSQQIQSsaqreFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAP 174
Cdd:pfam13177 73 IiEPEGQSIKIdQIRELQKEFSKSPYEGK-----KKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPT 147
|
170
....*....|.
gi 41393079 175 IRSRCLAVRVP 185
Cdd:pfam13177 148 IRSRCQIIRFK 158
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
3-59 |
5.05e-05 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 44.95 E-value: 5.05e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 41393079 3 LWVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPH-----LLVYGPSGAGKKTRIMCLLREL 59
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKEL 134
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
37-190 |
2.08e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 41.20 E-value: 2.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 37 HLLVYGPSGAGKKTRIMCLLRELYGAGVEKLRIEHQSITTPSKKKLEINTIASNYHlevnPSDAGNSDRVVIQELIKtva 116
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKA----SGSGELRLRLALALARK--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 117 qsqqiqssaqREFKVVLLTEVDRLTKDAQHALRR--------TMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPS 188
Cdd:smart00382 77 ----------LKPDVLILDEITSLLDAEQEALLLlleelrllLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRIVLLL 146
|
..
gi 41393079 189 VE 190
Cdd:smart00382 147 IL 148
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
3-345 |
3.23e-48 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 165.05 E-value: 3.23e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 3 LWVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGagvEKLRiehqsittpskkkl 82
Cdd:PRK00440 6 IWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYG---EDWR-------------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 83 eintiasNYHLEVNPSDAGNSDrvVIQELIKTVAQSQQIQSSaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLI 162
Cdd:PRK00440 69 -------ENFLELNASDERGID--VIRNKIKEFARTAPVGGA---PFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFI 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 163 LCCNSTSKVIAPIRSRCLAVRV-PLPSvEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALlmceacRVQQYPFS 241
Cdd:PRK00440 137 LSCNYSSKIIDPIQSRCAVFRFsPLKK-EAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAI------NALQAAAA 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 242 PDQDIPEtdwevylrETANAIVSQQSPQ------------RLLEVRARLYELLT-HCISPEVIMKGLVTELLS-NCDGHL 307
Cdd:PRK00440 210 TGKEVTE--------EAVYKITGTARPEeiremielalngDFTEAREKLRDLMIdYGLSGEDIIKQIHREVWSlDIPEEL 281
|
330 340 350
....*....|....*....|....*....|....*...
gi 41393079 308 KAEVAQMAAYYEHRLQLGNKAIYHLEAFVAKFMAIYKK 345
Cdd:PRK00440 282 KVELIDAIGEADFRITEGANERIQLEALLAKLALLGKK 319
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
3-339 |
8.94e-48 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 164.39 E-value: 8.94e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 3 LWVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGAGVEKLRIEHQSITTPSKKKL 82
Cdd:PRK12402 4 LWTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPWENNFTEFNVADFFDQGKK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 83 EINTIASNYHLEVNPSDAGNSDRVVIQELIKtvaqSQQIQSSAQREFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLI 162
Cdd:PRK12402 84 YLVEDPRFAHFLGTDKRIRSSKIDNFKHVLK----EYASYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 163 LCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALLMCEAcRVQQYPFSP 242
Cdd:PRK12402 160 IATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQT-AALAAGEIT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 243 DQDIPETDWEVYLRETANAIVSQQSPQRLLEVRARLYELL-THCISPEVIMKGLVTELLSNCDGHLKAEVAQMAAYYEHR 321
Cdd:PRK12402 239 MEAAYEALGDVGTDEVIESLLDAAEAGDFTDARKTLDDLLiDEGLSGGEVLEELLRVARSRYRGDNLARLHRLAADADAR 318
|
330
....*....|....*...
gi 41393079 322 LQLGNKAIYHLEAFVAKF 339
Cdd:PRK12402 319 LTDGANDRIQLEALLAEL 336
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
19-342 |
5.11e-34 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 127.01 E-value: 5.11e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 19 HKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKTRIMCLLRELYGagveklrieHQSITTPSKKKLEINTIASNYH---LE 94
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLC---------ENPEGGKACGQCHSRLMAAGNHpdlLE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 95 VNPSDAGNSDRV-VIQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIA 173
Cdd:COG0470 72 LNPEEKSDQIGIdQIRELGEFLSLTPLEG-----GRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLP 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 174 PIRSRCLAVRVPLPSVEEVCSVLsgvcRKEGllLPPELAKQIAEKSGRNLRKALLMCEAcrvqqypfspdqdipetdWEV 253
Cdd:COG0470 147 TIRSRCQVIRFRPPSEEEALAWL----REEG--VDEDALEAILRLAGGDPRAAINLLQA------------------LAG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 254 Y--LRETANAIVSQQSPQRLLEV--RARLYELLthcispEVIMKGLVTELLSNCDGHLKAEVAQMAAYYEHRLQLG-NKA 328
Cdd:COG0470 203 RkeLLEDLAALLSRDRALELLDAllKAEALELL------DWLLKWLLDNLPLEYAGEDLARAYEALSEADRRLGRYaNDR 276
|
330
....*....|....
gi 41393079 329 IyHLEAFVAKFMAI 342
Cdd:COG0470 277 L-LLEALLAKLGRL 289
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
4-227 |
2.85e-32 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 122.92 E-value: 2.85e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 4 WVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGAgveklriehqsittpskkkle 83
Cdd:PLN03025 3 WVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGP--------------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 84 intiasNYH---LEVNPSDAGNSDrvVIQELIKTVAQSQQIQSSAQRefKVVLLTEVDRLTKDAQHALRRTMEKYMATCR 160
Cdd:PLN03025 62 ------NYKeavLELNASDDRGID--VVRNKIKMFAQKKVTLPPGRH--KIVILDEADSMTSGAQQALRRTMEIYSNTTR 131
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 41393079 161 LILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKAL 227
Cdd:PLN03025 132 FALACNTSSKIIEPIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQAL 198
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
93-344 |
1.35e-23 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 102.22 E-value: 1.35e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 93 LEVNPSDAGNSDrvVIQELIKTVAQSQQIQSSaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVI 172
Cdd:PRK04132 600 LELNASDERGIN--VIREKVKEFARTKPIGGA---SFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKII 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 173 APIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALlmceacRVQQYPFSPDQDIpeTDWE 252
Cdd:PRK04132 675 EPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAI------NILQAAAALDDKI--TDEN 746
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 253 VYLretanaIVSQQSPQ------------RLLEVRARLYE-LLTHCISPEVIMKGLVTELLS-NCDGHLKAEVAQMAAYY 318
Cdd:PRK04132 747 VFL------VASRARPEdiremmllalkgNFLKAREKLREiLLKQGLSGEDVLVQMHREVFNlPIDEPKKVELADKIGEY 820
|
250 260
....*....|....*....|....*.
gi 41393079 319 EHRLQLGNKAIYHLEAFVAKFMAIYK 344
Cdd:PRK04132 821 NFRLVEGANEMIQLEALLAQFTLMGK 846
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
3-204 |
9.38e-18 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 82.73 E-value: 9.38e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 3 LWVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVYGPS-GAGKKTRIMCLLRELyGAGVeklriehqsittpskkk 81
Cdd:PHA02544 10 MWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSpGTGKTTVAKALCNEV-GAEV----------------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 82 leintiasnyhLEVNPSDagnsDRVviqELIKTVAQSQQIQSSAQREFKVVLLTEVDRL-TKDAQHALRRTMEKYMATCR 160
Cdd:PHA02544 72 -----------LFVNGSD----CRI---DFVRNRLTRFASTVSLTGGGKVIIIDEFDRLgLADAQRHLRSFMEAYSKNCS 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 41393079 161 LILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLS-------GVCRKEG 204
Cdd:PHA02544 134 FIITANNKNGIIEPLRSRCRVIDFGVPTKEEQIEMMKqmivrckGILEAEG 184
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
10-342 |
6.70e-17 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 80.62 E-value: 6.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 10 PTSLAKLDYHKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKT--RIM-----CllrelygagveklriEHQSITTP---- 77
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTlaRILakalnC---------------ENGPTGEPcgec 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 78 -SKKKleintIASNYHLEVNPSDAGNSDRVV--IQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTME- 153
Cdd:COG2812 71 eSCRA-----IAAGSHPDVIEIDAEASNIGVddIRELIEKVSYAPVEG-----RYKVYIIDEAHMLTTEAFNALLKTLEe 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 154 -----KymatcrLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALL 228
Cdd:COG2812 141 ppphvV------FILATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALS 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 229 MCeacrvqqypfspDQDIP--ETDWEVYLRETANAIVsQQSPQRLLEVRARLYE-----------LLTHCIspEVIMKGL 295
Cdd:COG2812 215 LL------------DQAIAfgLLDRRELLLDLLEALL-AGDVAALLALAEELAKrgrdlkrflddLLSLLR--DLLLLKL 279
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 41393079 296 VTELLSNCDGHLKAEVAQMAAYY-----EHRLQLGNKAIYHLEAFVAKFMAI 342
Cdd:COG2812 280 GPDAELLVNEDERERLQELARRLsperlLRAIQILLEARRELERNVNPRLAL 331
|
|
| PRK07940 |
PRK07940 |
DNA polymerase III subunit delta'; Validated |
129-226 |
7.99e-09 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236134 [Multi-domain] Cd Length: 394 Bit Score: 56.46 E-value: 7.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 129 FKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSgvcRKEGllLP 208
Cdd:PRK07940 118 WRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRHVALRTPSVEAVAEVLV---RRDG--VD 192
|
90
....*....|....*...
gi 41393079 209 PELAKQIAEKSGRNLRKA 226
Cdd:PRK07940 193 PETARRAARASQGHIGRA 210
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
1-232 |
2.05e-08 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 55.70 E-value: 2.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 1 MSLWVDKYRPTSLAKLDYHKEQANQLKNLVQcgDFPH------LLVYGPSGAGKKTRIMCLLRELygagveklriehqsi 74
Cdd:PRK04195 1 MMPWVEKYRPKTLSDVVGNEKAKEQLREWIE--SWLKgkpkkaLLLYGPPGVGKTSLAHALANDY--------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 75 ttpskkKLEIntiasnyhLEVNPSDAGNSDrvVIQeliKTVAQSQQIQSSAQREFKVVLLTEVDRL--TKDA--QHALRR 150
Cdd:PRK04195 64 ------GWEV--------IELNASDQRTAD--VIE---RVAGEAATSGSLFGARRKLILLDEVDGIhgNEDRggARAILE 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 151 TMEKymATCRLILCCN---STSKviAPIRSRCLAV---RVPLPSVEEVcsvLSGVCRKEGLLLPPELAKQIAEKSGRNLR 224
Cdd:PRK04195 125 LIKK--AKQPIILTANdpyDPSL--RELRNACLMIefkRLSTRSIVPV---LKRICRKEGIECDDEALKEIAERSGGDLR 197
|
....*...
gi 41393079 225 KALLMCEA 232
Cdd:PRK04195 198 SAINDLQA 205
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
7-229 |
7.41e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 53.72 E-value: 7.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVY-GPSGAGKKTRIMCLLRelygagveklRIEHQSITTPSKkklein 85
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFcGPRGVGKTTCARILAR----------KINQPGYDDPNE------ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 86 tiasNYHLEVNPSDAGNSDRVV-IQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILC 164
Cdd:PRK14970 74 ----DFSFNIFELDAASNNSVDdIRNLIDQVRIPPQTG-----KYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41393079 165 CNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALLM 229
Cdd:PRK14970 145 TTEKHKIIPTILSRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSI 209
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
21-179 |
7.44e-08 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 50.99 E-value: 7.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 21 EQANQLKNLVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGAGVEklriehqsittpskkkleintiasnyHLEVNPSDA 100
Cdd:cd00009 5 EAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAP--------------------------FLYLNASDL 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 101 GNSDrvVIQELIKTVAQSQQIQSSAQREFKVVLLTEVDRLTKDAQHALRRTMEKYM------ATCRLILCCNSTS--KVI 172
Cdd:cd00009 59 LEGL--VVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNdlridrENVRVIGATNRPLlgDLD 136
|
....*..
gi 41393079 173 APIRSRC 179
Cdd:cd00009 137 RALYDRL 143
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
7-231 |
1.22e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 53.23 E-value: 1.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVY-GPSGAGKKT--RIMcllrelygagVEKLRIEHQSITTPSKKKLE 83
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFaGPRGTGKTTvaRIL----------AKSLNCENRKGVEPCNECRA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 84 INTIASNYHLEVNPSDAGnSDRVV--IQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRL 161
Cdd:PRK14962 77 CRSIDEGTFMDVIELDAA-SNRGIdeIRKIRDAVGYRPMEG-----KYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVF 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 162 ILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALLMCE 231
Cdd:PRK14962 151 VLATTNLEKVPPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLE 220
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
7-231 |
3.44e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 51.87 E-value: 3.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVY-GPSGAGKKT--RIMcllrelygagVEKLRIEHQSITTPSKKK-- 81
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFfGPRGVGKTTiaRIL----------AKRLNCENPIGNEPCNECts 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 82 -LEINTIASNYHLEVNPsdAGNSDRVVIQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCR 160
Cdd:PRK14956 81 cLEITKGISSDVLEIDA--ASNRGIENIRELRDNVKFAPMGG-----KYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIV 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 41393079 161 LILCCNSTSKVIAPIRSRC---LAVRVPLPSVEEVCSVLsgvCRKEGLLLPPELAKQIAEKSGRNLRKALLMCE 231
Cdd:PRK14956 154 FILATTEFHKIPETILSRCqdfIFKKVPLSVLQDYSEKL---CKIENVQYDQEGLFWIAKKGDGSVRDMLSFME 224
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
7-227 |
7.88e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 50.82 E-value: 7.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVY-GPSGAGKKT--RIMcllrelygagVEKLRIEHQSITTPSKKKLE 83
Cdd:PRK14960 8 KYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFtGTRGVGKTTiaRIL----------AKCLNCETGVTSTPCEVCAT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 84 INTIASNYHLEVNPSDAGNSDRVV-IQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLI 162
Cdd:PRK14960 78 CKAVNEGRFIDLIEIDAASRTKVEdTRELLDNVPYAPTQG-----RFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41393079 163 LCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKAL 227
Cdd:PRK14960 153 FATTDPQKLPITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDAL 217
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
7-227 |
8.60e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 50.58 E-value: 8.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKTrimcllrelygagVEKLRIEHQSITTPSKKKLEIN 85
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIAEGRVAHaYLFTGPRGVGKTS-------------TARILAKAVNCTTNDPKGRPCG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 86 T------IASNYHLEVNPSDAGNSDRVV-IQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMAT 158
Cdd:PRK14950 76 TcemcraIAEGSAVDVIEMDAASHTSVDdAREIIERVQFRPALA-----RYKVYIIDEVHMLSTAAFNALLKTLEEPPPH 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 41393079 159 CRLILCCNSTSKVIAPIRSRC---LAVRVplpSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKAL 227
Cdd:PRK14950 151 AIFILATTEVHKVPATILSRCqrfDFHRH---SVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAE 219
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
7-231 |
1.86e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 49.40 E-value: 1.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKT--RI--MCLlrelygagveklRIEHQSITTPSKKK 81
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTcaRIisLCL------------NCSNGPTSDPCGTC 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 82 LEINTIASNYHLEVNPSDAGNSDRVviqELIKTVAQSQQIQSSAQReFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRL 161
Cdd:PRK14964 74 HNCISIKNSNHPDVIEIDAASNTSV---DDIKVILENSCYLPISSK-FKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKF 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 162 ILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALLMCE 231
Cdd:PRK14964 150 ILATTEVKKIPVTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLE 219
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
129-227 |
8.69e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 47.51 E-value: 8.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 129 FKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLP 208
Cdd:PRK14953 120 YKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYE 199
|
90
....*....|....*....
gi 41393079 209 PELAKQIAEKSGRNLRKAL 227
Cdd:PRK14953 200 EKALDLLAQASEGGMRDAA 218
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
18-185 |
1.35e-05 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 44.89 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 18 YHKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKTRIMCLLRELYGagveklriEHQSITTPSKKKLEINTIASNYHLEVN 96
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFC--------EEPGDDLPCGQCRSCRRIESGNHPDLV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 97 P-SDAGNSDRV-VIQELIKTVAQSQQIQSsaqreFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAP 174
Cdd:pfam13177 73 IiEPEGQSIKIdQIRELQKEFSKSPYEGK-----KKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPT 147
|
170
....*....|.
gi 41393079 175 IRSRCLAVRVP 185
Cdd:pfam13177 148 IRSRCQIIRFK 158
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
7-227 |
1.95e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 46.23 E-value: 1.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVY-GPSGAGKKTrimcllrelYGAGVEKLRIEHQSITTPSKKKLEiN 85
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFtGTRGVGKTT---------LGRLLAKCLNCKTGVTAEPCNKCE-N 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 86 TIASNYHLEVNPSDAGNSDRVVIQElIKTVAQSQQIQSSAQReFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCC 165
Cdd:PRK14957 79 CVAINNNSFIDLIEIDAASRTGVEE-TKEILDNIQYMPSQGR-YKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILAT 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 41393079 166 NSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKAL 227
Cdd:PRK14957 157 TDYHKIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDAL 218
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
4-48 |
2.47e-05 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 46.37 E-value: 2.47e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 41393079 4 WVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVYGPSGAGK 48
Cdd:PRK04132 9 WVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK 53
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
7-273 |
2.80e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 45.85 E-value: 2.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKT--RIMcllrelygagVEKLRIEHQSITTPSKKKLE 83
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHaYLLTGTRGVGKTTiaRIL----------AKSLNCENAQHGEPCGVCQS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 84 INTIASNYHLEVNPSDAG-NSDRVVIQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLI 162
Cdd:PRK08691 79 CTQIDAGRYVDLLEIDAAsNTGIDNIREVLENAQYAPTAG-----KYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 163 LCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKAL-LMCEACRVQQYPFS 241
Cdd:PRK08691 154 LATTDPHKVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALsLLDQAIALGSGKVA 233
|
250 260 270
....*....|....*....|....*....|....*
gi 41393079 242 PD---QDIPETDWEvYLRETANAIVSQQSPQRLLE 273
Cdd:PRK08691 234 ENdvrQMIGAVDKQ-YLYELLTGIINQDGAALLAK 267
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
187-252 |
4.07e-05 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 40.98 E-value: 4.07e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 41393079 187 PSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALLMCEACRVQqypfspDQDIPETDWE 252
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAG------GGVITEEDVY 60
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
3-59 |
5.05e-05 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 44.95 E-value: 5.05e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 41393079 3 LWVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPH-----LLVYGPSGAGKKTRIMCLLREL 59
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKEL 134
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
3-59 |
5.98e-05 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 43.41 E-value: 5.98e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 41393079 3 LWVDKYRPTSLAKLDYHKEQANQLKNLVQCGDFPH-----LLVYGPSGAGKKTRIMCLLREL 59
Cdd:pfam03215 8 QWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL 69
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
6-232 |
8.56e-05 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 43.92 E-value: 8.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 6 DKYRPTSLAklDY----H---KEQAnqLKNLVQCGDFPHLLVYGPSGAGKKT--RIMcllrelygAGVEKLRIEHQSITT 76
Cdd:PRK13342 4 ERMRPKTLD--EVvgqeHllgPGKP--LRRMIEAGRLSSMILWGPPGTGKTTlaRII--------AGATDAPFEALSAVT 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 77 PSKKklEINTIASNYhlevnpsdagnsdRVVIQELIKTVaqsqqiqssaqrefkvVLLTEVDRLTKDAQHALRRTMEKYM 156
Cdd:PRK13342 72 SGVK--DLREVIEEA-------------RQRRSAGRRTI----------------LFIDEIHRFNKAQQDALLPHVEDGT 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 157 ATcrLILCcnSTS----KVIAPIRSRClavRV----PLpSVEEVCSVLS-GVCRKEGLL--LPPELAKQIAEKSGRNLRK 225
Cdd:PRK13342 121 IT--LIGA--TTEnpsfEVNPALLSRA---QVfelkPL-SEEDIEQLLKrALEDKERGLveLDDEALDALARLANGDARR 192
|
....*..
gi 41393079 226 ALLMCEA 232
Cdd:PRK13342 193 ALNLLEL 199
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
7-229 |
8.69e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 44.38 E-value: 8.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPH-LLVYGPSGAGKKT--RIM-----CLLRelyGAGVEKLRiEHQSIttps 78
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTcaRIFaktinCQNL---TADGEACN-ECESC---- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 79 kkkLEINTIAS-NYHlEVnpsDAGNSDRVV-IQELIKTVAQSQQIQssaqrEFKVVLLTEVDRLTKDAQHALRRTMEKYM 156
Cdd:PRK14971 82 ---VAFNEQRSyNIH-EL---DAASNNSVDdIRNLIEQVRIPPQIG-----KYKIYIIDEVHMLSQAAFNAFLKTLEEPP 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41393079 157 ATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKALLM 229
Cdd:PRK14971 150 SYAIFILATTEKHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSI 222
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
7-226 |
1.19e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 43.73 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 7 KYRPTSLAKLDYHKEQANQLKNLVQCGDFPHLLVY-GPSGAGKKTRIMCLLRELYGAGVEKLRIEHQSITTPSKKKLEIN 85
Cdd:PRK14955 9 KYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFsGLRGVGKTTAARVFAKAVNCQRMIDDADYLQEVTEPCGECESCR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 86 TIASNYHLEVNPSDAGNSDRVviqELIKTVAQSQQIQSSAQReFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCC 165
Cdd:PRK14955 89 DFDAGTSLNISEFDAASNNSV---DDIRLLRENVRYGPQKGR-YRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFAT 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 41393079 166 NSTSKVIAPIRSRCLAV---RVPLPSVEEvcsVLSGVCRKEGLLLPPELAKQIAEKSGRNLRKA 226
Cdd:PRK14955 165 TELHKIPATIASRCQRFnfkRIPLEEIQQ---QLQGICEAEGISVDADALQLIGRKAQGSMRDA 225
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
37-190 |
2.08e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 41.20 E-value: 2.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 37 HLLVYGPSGAGKKTRIMCLLRELYGAGVEKLRIEHQSITTPSKKKLEINTIASNYHlevnPSDAGNSDRVVIQELIKtva 116
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKA----SGSGELRLRLALALARK--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 117 qsqqiqssaqREFKVVLLTEVDRLTKDAQHALRR--------TMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPS 188
Cdd:smart00382 77 ----------LKPDVLILDEITSLLDAEQEALLLlleelrllLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRIVLLL 146
|
..
gi 41393079 189 VE 190
Cdd:smart00382 147 IL 148
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
129-227 |
4.99e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 41.97 E-value: 4.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 129 FKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLP 208
Cdd:PRK14959 120 YKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYD 199
|
90
....*....|....*....
gi 41393079 209 PELAKQIAEKSGRNLRKAL 227
Cdd:PRK14959 200 PAAVRLIARRAAGSVRDSM 218
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
129-226 |
6.41e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 41.68 E-value: 6.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 129 FKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLP 208
Cdd:PRK06647 120 YRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYE 199
|
90
....*....|....*...
gi 41393079 209 PELAKQIAEKSGRNLRKA 226
Cdd:PRK06647 200 DEALKWIAYKSTGSVRDA 217
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
128-234 |
7.68e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 41.38 E-value: 7.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 128 EFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLL 207
Cdd:PRK06645 128 KHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKT 207
|
90 100
....*....|....*....|....*..
gi 41393079 208 PPELAKQIAEKSGRNLRKALLMCEACR 234
Cdd:PRK06645 208 DIEALRIIAYKSEGSARDAVSILDQAA 234
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
130-179 |
7.96e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 40.79 E-value: 7.96e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 41393079 130 KVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRC 179
Cdd:PRK05564 95 KVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRC 144
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
129-226 |
8.77e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 41.08 E-value: 8.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 129 FKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAV---RVPLpsvEEVCSVLSGVCRKEGL 205
Cdd:PRK14954 128 YRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFnfkRIPL---DEIQSQLQMICRAEGI 204
|
90 100
....*....|....*....|.
gi 41393079 206 LLPPELAKQIAEKSGRNLRKA 226
Cdd:PRK14954 205 QIDADALQLIARKAQGSMRDA 225
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
129-227 |
1.10e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 40.89 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 129 FKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLP 208
Cdd:PRK14969 120 FKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFD 199
|
90
....*....|....*....
gi 41393079 209 PELAKQIAEKSGRNLRKAL 227
Cdd:PRK14969 200 ATALQLLARAAAGSMRDAL 218
|
|
| PRK05707 |
PRK05707 |
DNA polymerase III subunit delta'; Validated |
129-192 |
1.16e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180215 [Multi-domain] Cd Length: 328 Bit Score: 40.46 E-value: 1.16e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 41393079 129 FKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEV 192
Cdd:PRK05707 107 RKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEES 170
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
130-226 |
1.53e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 40.21 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 130 KVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRVPLPSVEEVCSVLSGVCRKEGLLLPP 209
Cdd:PRK14963 118 KVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEP 197
|
90
....*....|....*..
gi 41393079 210 ELAKQIAEKSGRNLRKA 226
Cdd:PRK14963 198 EALQLVARLADGAMRDA 214
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
128-229 |
4.81e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 38.48 E-value: 4.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41393079 128 EFKVVLLTEVDRLTKDAQHALRRTMEKYMATCRLILCCNSTSKVIAPIRSRCLAVRV-PLpSVEEVCSVLSGVcrkeGLL 206
Cdd:PRK09112 141 NWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCQPISLkPL-DDDELKKALSHL----GSS 215
|
90 100
....*....|....*....|....*
gi 41393079 207 LPP--ELAKQIAEKSGRNLRKALLM 229
Cdd:PRK09112 216 QGSdgEITEALLQRSKGSVRKALLL 240
|
|
|