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Conserved domains on  [gi|206597554|ref|NP_997248|]
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arylacetamide deacetylase-like 2 precursor [Homo sapiens]

Protein Classification

alpha/beta hydrolase( domain architecture ID 11171394)

alpha/beta hydrolase catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  37582413|12369917|19508187

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase_3 pfam07859
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 107-372 8.85e-54

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


:

Pssm-ID: 400284 [Multi-domain]  Cd Length: 208  Bit Score: 177.40  E-value: 8.85e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  107 VIYFHGGGFCFGSSkqRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKFflLEKILTKYGVDPTRICIA 186
Cdd:pfam07859   1 LVYFHGGGFVLGSA--DTHDRLCRRLAAEAGAVVVSVDYRLAPEHPFPAAYDDAYAALRW--LAEQAAELGADPSRIAVA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  187 GDSSGGNLATAVTQQVQNDAEIkhKIKMQVLLYPGL-QITDSYLPSHRENEHGIVLTRDvaiklvslyftkdeALPWAmr 265
Cdd:pfam07859  77 GDSAGGNLAAAVALRARDEGLP--KPAGQVLIYPGTdLRTESPSYLAREFADGPLLTRA--------------AMDWF-- 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  266 rnqhmplesrhlfkfvnWSILLPEKYRkdyvytepilgglsyslpglTDSRALPLLANDsqLQNLPLTYILTCQHDLLRD 345
Cdd:pfam07859 139 -----------------WRLYLPGADR--------------------DDPLASPLFASD--LSGLPPALVVVAEFDPLRD 179

                         250       260
                  ....*....|....*....|....*..
gi 206597554  346 DGLMYVTRLRNVGVQVVHEHIEDGIHG 372
Cdd:pfam07859 180 EGEAYAERLRAAGVPVELIEYPGMPHG 206
 
Name Accession Description Interval E-value
Abhydrolase_3 pfam07859
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 107-372 8.85e-54

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 400284 [Multi-domain]  Cd Length: 208  Bit Score: 177.40  E-value: 8.85e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  107 VIYFHGGGFCFGSSkqRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKFflLEKILTKYGVDPTRICIA 186
Cdd:pfam07859   1 LVYFHGGGFVLGSA--DTHDRLCRRLAAEAGAVVVSVDYRLAPEHPFPAAYDDAYAALRW--LAEQAAELGADPSRIAVA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  187 GDSSGGNLATAVTQQVQNDAEIkhKIKMQVLLYPGL-QITDSYLPSHRENEHGIVLTRDvaiklvslyftkdeALPWAmr 265
Cdd:pfam07859  77 GDSAGGNLAAAVALRARDEGLP--KPAGQVLIYPGTdLRTESPSYLAREFADGPLLTRA--------------AMDWF-- 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  266 rnqhmplesrhlfkfvnWSILLPEKYRkdyvytepilgglsyslpglTDSRALPLLANDsqLQNLPLTYILTCQHDLLRD 345
Cdd:pfam07859 139 -----------------WRLYLPGADR--------------------DDPLASPLFASD--LSGLPPALVVVAEFDPLRD 179

                         250       260
                  ....*....|....*....|....*..
gi 206597554  346 DGLMYVTRLRNVGVQVVHEHIEDGIHG 372
Cdd:pfam07859 180 EGEAYAERLRAAGVPVELIEYPGMPHG 206
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
92-401 1.17e-46

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 158.88  E-value: 1.17e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  92 RLYLPKrKSETRRRAVIYFHGGGFCFGSSkqRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKfFLLEK 171
Cdd:COG0657    2 DVYRPA-GAKGPLPVVVYFHGGGWVSGSK--DTHDPLARRLAARAGAAVVSVDYRLAPEHPFPAALEDAYAALR-WLRAN 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554 172 IlTKYGVDPTRICIAGDSSGGNLATAVTQQVQNDAEIkhKIKMQVLLYPglqitdsylpshrenehgivltrdvaiklvs 251
Cdd:COG0657   78 A-AELGIDPDRIAVAGDSAGGHLAAALALRARDRGGP--RPAAQVLIYP------------------------------- 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554 252 lyftkdealpwamrrnqhmplesrhlfkfvnwsillpekyrkdyvytepilgglsyslpgLTDSRALPLLANdsqLQNLP 331
Cdd:COG0657  124 ------------------------------------------------------------VLDLTASPLRAD---LAGLP 140

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554 332 LTYILTCQHDLLRDDGLMYVTRLRNVGVQVVHEHIEDGIHGALSFMTSPfylrLGLRIRDMYVSWLDKNL 401
Cdd:COG0657  141 PTLIVTGEADPLVDESEALAAALRAAGVPVELHVYPGGGHGFGLLAGLP----EARAALAEIAAFLRRAL 206
PRK10162 PRK10162
acetyl esterase;
83-233 7.13e-20

acetyl esterase;


Pssm-ID: 236660 [Multi-domain]  Cd Length: 318  Bit Score: 89.39  E-value: 7.13e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  83 DTTFVDIPVRLYLPKRKSetrRRAVIYFHGGGFCFGSSKQRafDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLA 162
Cdd:PRK10162  63 PTPYGQVETRLYYPQPDS---QATLFYLHGGGFILGNLDTH--DRIMRLLASYSGCTVIGIDYTLSPEARFPQAIEEIVA 137

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 206597554 163 AVKFFllEKILTKYGVDPTRICIAGDSSGGNLATAVTQQVQnDAEIKHKIKMQVLLYPGL-QITDSylPSHR 233
Cdd:PRK10162 138 VCCYF--HQHAEDYGINMSRIGFAGDSAGAMLALASALWLR-DKQIDCGKVAGVLLWYGLyGLRDS--VSRR 204
 
Name Accession Description Interval E-value
Abhydrolase_3 pfam07859
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 107-372 8.85e-54

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 400284 [Multi-domain]  Cd Length: 208  Bit Score: 177.40  E-value: 8.85e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  107 VIYFHGGGFCFGSSkqRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKFflLEKILTKYGVDPTRICIA 186
Cdd:pfam07859   1 LVYFHGGGFVLGSA--DTHDRLCRRLAAEAGAVVVSVDYRLAPEHPFPAAYDDAYAALRW--LAEQAAELGADPSRIAVA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  187 GDSSGGNLATAVTQQVQNDAEIkhKIKMQVLLYPGL-QITDSYLPSHRENEHGIVLTRDvaiklvslyftkdeALPWAmr 265
Cdd:pfam07859  77 GDSAGGNLAAAVALRARDEGLP--KPAGQVLIYPGTdLRTESPSYLAREFADGPLLTRA--------------AMDWF-- 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  266 rnqhmplesrhlfkfvnWSILLPEKYRkdyvytepilgglsyslpglTDSRALPLLANDsqLQNLPLTYILTCQHDLLRD 345
Cdd:pfam07859 139 -----------------WRLYLPGADR--------------------DDPLASPLFASD--LSGLPPALVVVAEFDPLRD 179

                         250       260
                  ....*....|....*....|....*..
gi 206597554  346 DGLMYVTRLRNVGVQVVHEHIEDGIHG 372
Cdd:pfam07859 180 EGEAYAERLRAAGVPVELIEYPGMPHG 206
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
92-401 1.17e-46

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 158.88  E-value: 1.17e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  92 RLYLPKrKSETRRRAVIYFHGGGFCFGSSkqRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKfFLLEK 171
Cdd:COG0657    2 DVYRPA-GAKGPLPVVVYFHGGGWVSGSK--DTHDPLARRLAARAGAAVVSVDYRLAPEHPFPAALEDAYAALR-WLRAN 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554 172 IlTKYGVDPTRICIAGDSSGGNLATAVTQQVQNDAEIkhKIKMQVLLYPglqitdsylpshrenehgivltrdvaiklvs 251
Cdd:COG0657   78 A-AELGIDPDRIAVAGDSAGGHLAAALALRARDRGGP--RPAAQVLIYP------------------------------- 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554 252 lyftkdealpwamrrnqhmplesrhlfkfvnwsillpekyrkdyvytepilgglsyslpgLTDSRALPLLANdsqLQNLP 331
Cdd:COG0657  124 ------------------------------------------------------------VLDLTASPLRAD---LAGLP 140

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554 332 LTYILTCQHDLLRDDGLMYVTRLRNVGVQVVHEHIEDGIHGALSFMTSPfylrLGLRIRDMYVSWLDKNL 401
Cdd:COG0657  141 PTLIVTGEADPLVDESEALAAALRAAGVPVELHVYPGGGHGFGLLAGLP----EARAALAEIAAFLRRAL 206
PRK10162 PRK10162
acetyl esterase;
83-233 7.13e-20

acetyl esterase;


Pssm-ID: 236660 [Multi-domain]  Cd Length: 318  Bit Score: 89.39  E-value: 7.13e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  83 DTTFVDIPVRLYLPKRKSetrRRAVIYFHGGGFCFGSSKQRafDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLA 162
Cdd:PRK10162  63 PTPYGQVETRLYYPQPDS---QATLFYLHGGGFILGNLDTH--DRIMRLLASYSGCTVIGIDYTLSPEARFPQAIEEIVA 137

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 206597554 163 AVKFFllEKILTKYGVDPTRICIAGDSSGGNLATAVTQQVQnDAEIKHKIKMQVLLYPGL-QITDSylPSHR 233
Cdd:PRK10162 138 VCCYF--HQHAEDYGINMSRIGFAGDSAGAMLALASALWLR-DKQIDCGKVAGVLLWYGLyGLRDS--VSRR 204
BD-FAE pfam20434
BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, ...
 93-196 5.83e-19

BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, previously known as bifunctional carbohydrate esterase (CE)), which is active on complex natural xylans and was identified as the basis of a monophyletic clade gathering all homologs identified in PULs (polysaccharide utilization loci) predicted to act on xylan. It adopts an alpha-beta-hydrolase fold with the catalytic triad Ser-Asp-His. This new family of proteins is a new candidate for biomass processing due to its capacity to remove ferulic acid and acetic acid from natural corn and birchwood xylan substrates.


Pssm-ID: 466583 [Multi-domain]  Cd Length: 215  Bit Score: 84.54  E-value: 5.83e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554   93 LYLPKrKSETRRRAVIYFHGGGFCFGSSKqrAFDFLNRWTANTL-DA--VVVGVDYRLAPQHHFPAQFEDGLAAVKFflL 169
Cdd:pfam20434   3 IYLPK-NAKGPYPVVIWIHGGGWNSGDKE--ADMGFMTNTVKALlKAgyAVASINYRLSTDAKFPAQIQDVKAAIRF--L 77

                          90       100
                  ....*....|....*....|....*..
gi 206597554  170 EKILTKYGVDPTRICIAGDSSGGNLAT 196
Cdd:pfam20434  78 RANAAKYGIDTNKIALMGFSAGGHLAL 104
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
87-198 2.01e-09

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 57.33  E-value: 2.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  87 VDIPVRLYLPKrkSETRRRAVIYFHGGGfcfgSSKQRAFDFLNRWTANtLDAVVVGVDYR---LAPQHHFPAQFEDGLAA 163
Cdd:COG1506    8 TTLPGWLYLPA--DGKKYPVVVYVHGGP----GSRDDSFLPLAQALAS-RGYAVLAPDYRgygESAGDWGGDEVDDVLAA 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 206597554 164 VKFfllekILTKYGVDPTRICIAGDSSGGNLATAV 198
Cdd:COG1506   81 IDY-----LAARPYVDPDRIGIYGHSYGGYMALLA 110
COG4099 COG4099
Predicted peptidase [General function prediction only];
81-195 4.94e-08

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 53.43  E-value: 4.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  81 VTDTTFVDIPVRLYLPKRKSETRRR-AVIYFHGGGFcFGSS-----KQRAFDFLNRWTANTLDAVVVgvdyrlAPQHHFP 154
Cdd:COG4099   25 TDPSDGDTLPYRLYLPKGYDPGKKYpLVLFLHGAGE-RGTDnekqlTHGAPKFINPENQAKFPAIVL------APQCPED 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 206597554 155 AQFEDGLAAVKFF-LLEKILTKYGVDPTRICIAGDSSGGNLA 195
Cdd:COG4099   98 DYWSDTKALDAVLaLLDDLIAEYRIDPDRIYLTGLSMGGYGT 139
COesterase pfam00135
Carboxylesterase family;
93-192 8.12e-07

Carboxylesterase family;


Pssm-ID: 395084 [Multi-domain]  Cd Length: 513  Bit Score: 50.77  E-value: 8.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554   93 LYL----PKRKSETRRRA--VIYFHGGGFCFGSSKQRAFDFLnrwtANTLDAVVVGVDYRLAP-------QHHFP--AQF 157
Cdd:pfam00135  86 LYLnvytPKELKENKNKLpvMVWIHGGGFMFGSGSLYDGSYL----AAEGDVIVVTINYRLGPlgflstgDDEAPgnYGL 161

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 206597554  158 EDGLAAVKFflLEKILTKYGVDPTRICIAGDSSGG 192
Cdd:pfam00135 162 LDQVLALRW--VQENIASFGGDPNRVTLFGESAGA 194
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 92-192 7.13e-06

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 47.31  E-value: 7.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  92 RLYLPKRKSETRRRA-VIYFHGGGfcfgsskQRAFDFLN--RWT--ANTLDAVVVGVD-YRLAPQHHF----PAQFEDGL 161
Cdd:COG3509   40 RLYVPAGYDGGAPLPlVVALHGCG-------GSAADFAAgtGLNalADREGFIVVYPEgTGRAPGRCWnwfdGRDQRRGR 112

                         90       100       110
                 ....*....|....*....|....*....|...
gi 206597554 162 AAVKFF--LLEKILTKYGVDPTRICIAGDSSGG 192
Cdd:COG3509  113 DDVAFIaaLVDDLAARYGIDPKRVYVTGLSAGG 145
PnbA COG2272
Carboxylesterase type B [Lipid transport and metabolism];
93-192 9.50e-06

Carboxylesterase type B [Lipid transport and metabolism];


Pssm-ID: 441873  Cd Length: 500  Bit Score: 47.58  E-value: 9.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  93 LYL----PkRKSETRRRAVI-YFHGGGFCFGSSKQRAFDflnrwtANTL---DAVVVGVDYRL------------APQHH 152
Cdd:COG2272   90 LYLnvwtP-ALAAGAKLPVMvWIHGGGFVSGSGSEPLYD------GAALarrGVVVVTINYRLgalgflalpalsGESYG 162

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 206597554 153 FPAQF--EDGLAAVKF-------FllekiltkyGVDPTRICIAGDSSGG 192
Cdd:COG2272  163 ASGNYglLDQIAALRWvrdniaaF---------GGDPDNVTIFGESAGA 202
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 93-204 4.41e-05

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 44.52  E-value: 4.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  93 LYLPKRKSETRRrAVIYFHGggfcFGSSKQRAFDFLNRWTANTLDAVVVgvDYRlapqHH-----FPAQFE-----DGLA 162
Cdd:COG1073   27 LYLPAGASKKYP-AVVVAHG----NGGVKEQRALYAQRLAELGFNVLAF--DYR----GYgesegEPREEGsperrDARA 95

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 206597554 163 AVKFfllekILTKYGVDPTRICIAGDSSGGNLATAVTQQVQN 204
Cdd:COG1073   96 AVDY-----LRTLPGVDPERIGLLGISLGGGYALNAAATDPR 132
Esterase pfam00756
Putative esterase; This family contains Esterase D. However it is not clear if all members of ...
 88-192 6.46e-05

Putative esterase; This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.


Pssm-ID: 395613 [Multi-domain]  Cd Length: 246  Bit Score: 43.99  E-value: 6.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554   88 DIPVRLYLPKRKSETRRRAVIYFHGGGFCFGSSkqRAFDFLNRWTA--NTLDAVVVGVDY-------------RLAPQHH 152
Cdd:pfam00756   7 EMKVQVYLPEDYPPGRKYPVLYLLDGTGWFQNG--PAKEGLDRLAAsgEIPPVIIVGSPRggevsfysdwdrgLNATEGP 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 206597554  153 FPAQFEDGLAAVkffLLEKILTKYGVDPTRICIAGDSSGG 192
Cdd:pfam00756  85 GAYAYETFLTQE---LPPLLDANFPTAPDGRALAGQSMGG 121
YbbA COG2819
Predicted hydrolase of the alpha/beta superfamily [General function prediction only];
78-196 2.31e-04

Predicted hydrolase of the alpha/beta superfamily [General function prediction only];


Pssm-ID: 442067 [Multi-domain]  Cd Length: 250  Bit Score: 42.28  E-value: 2.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  78 YITVTDTTFVDIP---------VRLYLPKRKSETRRR-AVIYFHGGGFCFGSSKQrAFDFLNRWTANTLDAVVVGVDY-- 145
Cdd:COG2819    1 LIALGQTEYFTLEspilgedrrIRVYLPPGYDAPEKRyPVLYMLDGQNLFDALAG-AVGTLSRLEGGIPPAIVVGIGNgd 79

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 206597554 146 ----RL------APQHHFPAQFEDGLAAvKF--FLLEKIL----TKYGVDPTRICIAGDSSGGNLAT 196
Cdd:COG2819   80 dgerRLrdytppPAPGYPGPGGPGGGAD-AFlrFLEEELKpyidKRYRTDPERTGLIGHSLGGLFSL 145
YpfH COG0400
Predicted esterase [General function prediction only];
100-198 2.34e-04

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 41.82  E-value: 2.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554 100 SETRRRAVIYFHGggfcFGSSKQRAFDFLNRWtaNTLDAVVVGVDyrlAPQHHFPAQF-------------EDGL-AAVK 165
Cdd:COG0400    1 GGPAAPLVVLLHG----YGGDEEDLLPLAPEL--ALPGAAVLAPR---APVPEGPGGRawfdlsflegredEEGLaAAAE 71

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 206597554 166 FF--LLEKILTKYGVDPTRICIAGDSSGGNLATAV 198
Cdd:COG0400   72 ALaaFIDELEARYGIDPERIVLAGFSQGAAMALSL 106
Fes COG2382
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
84-192 2.55e-03

Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];


Pssm-ID: 441948 [Multi-domain]  Cd Length: 314  Bit Score: 39.45  E-value: 2.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 206597554  84 TTFVDIPVRLYLPKR-KSETRRRAVIYFHGGGfcfGSSKQRAFDFLNrwTANTLDA----------VVVGVDYRLAPQHh 152
Cdd:COG2382   90 ALGRTRRVWVYLPPGyDNPGKKYPVLYLLDGG---GGDEQDWFDQGR--LPTILDNliaagkippmIVVMPDGGDGGDR- 163

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 206597554 153 fpaqFEDGLAAVKF--FLLEKIL----TKYGV--DPTRICIAGDSSGG 192
Cdd:COG2382  164 ----GTEGPGNDAFerFLAEELIpfveKNYRVsaDPEHRAIAGLSMGG 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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