|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
7-305 |
1.81e-28 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 118.09 E-value: 1.81e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 7 HRVRFFEYVPSGIRALAFNQHNERMAAAKMNGSVEIFHcsdrffqekIIPGREQAGIEGLT-WV--------GERLFSAG 77
Cdd:COG2319 111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWD---------LATGKLLRTLTGHSgAVtsvafspdGKLLASGS 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 78 LNGVITEYDLTNQRVKYTIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQfeRNLDRQKGRIISLSWHPSGS 157
Cdd:COG2319 182 DDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL--RTLTGHSGSVRSVAFSPDGR 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 158 KIAAGMMD-MIQVFNVETGHSKHRIlvdrgygtsRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLIKSHNITK 235
Cdd:COG2319 260 LLASGSADgTVRLWDLATGELLRTL---------TGHSGGVNSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHT 330
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 47086123 236 SDVLSLSVSQNEDSIVAGTSEGFVvqfqflsmvlenneKDW-----VRTRTFRNHTHDVRAVAeIT---TAVVSGGMD 305
Cdd:COG2319 331 GAVRSVAFSPDGKTLASGSDDGTV--------------RLWdlatgELLRTLTGHTGAVTSVA-FSpdgRTLASGSAD 393
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
16-305 |
1.08e-20 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 92.78 E-value: 1.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 16 PSGIRALAFNQHNERMAAAKMNGSVEIFHCSDRFFQEkiipgREQAGIEGLTWV-----GERLFSAGLNGVITEYDLTNQ 90
Cdd:cd00200 9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLR-----TLKGHTGPVRDVaasadGTYLASGSSDKTIRLWDLETG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 91 RVKYTIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQFErnLDRQKGRIISLSWHPSGSKIAAGMMD-MIQV 169
Cdd:cd00200 84 ECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTT--LRGHTDWVNSVAFSPDGTFVASSSQDgTIKL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 170 FNVETGHSKHRIlvdrgygtsRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLIKSHNITKSDVLSLSVSQNED 248
Cdd:cd00200 162 WDLRTGKCVATL---------TGHTGEVNSVAFSPDGeKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGY 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 47086123 249 SIVAGTSEGFVVQFqflsmvlenNEKDWVRTRTFRNHTHDVRAVA--EITTAVVSGGMD 305
Cdd:cd00200 233 LLASGSEDGTIRVW---------DLRTGECVQTLSGHTNSVTSLAwsPDGKRLASGSAD 282
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
189-549 |
1.28e-17 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 85.73 E-value: 1.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 189 TSRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLIKSHNITKSDVLSLSVSQNEDSIVAGTSEGFVVQFqflsm 267
Cdd:COG2319 73 TLLGHTAAVLSVAFSPDGrLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLW----- 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 268 vlenNEKDWVRTRTFRNHTHDVRAVAeIT---TAVVSGGMDTQLVVRPLLDkhevkssasklrkiqfphrslvscarkaG 344
Cdd:COG2319 148 ----DLATGKLLRTLTGHSGAVTSVA-FSpdgKLLASGSDDGTVRLWDLAT----------------------------G 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 345 TLLFQYPGHlelwrlgesegegipgsslllkrkpekllhlkvkgEDHIRCSAVSPCGEWIAY-STTSSLRLYKLHcdsnn 423
Cdd:COG2319 195 KLLRTLTGH-----------------------------------TGAVRSVAFSPDGKLLASgSADGTVRLWDLA----- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 424 vSITKISKLPKVLGSASQLCFSSDSTHLFSASTQSSVHMVSLSQPECKfvatfKTKSGSHQAIHLLAASEDGKWLASANI 503
Cdd:COG2319 235 -TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELL-----RTLTGHSGGVNSVAFSPDGKLLASGSD 308
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 47086123 504 DNEVHIYNLQTRKAHCTVPIYSSAVSAMAIHPTTNCLFMVHADQQI 549
Cdd:COG2319 309 DGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTV 354
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
187-549 |
5.60e-12 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 66.97 E-value: 5.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 187 YGTSRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLI---KSHNITKSDVLSLSVSQnedSIVAGTSEGFVVQF 262
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGkLLATGSGDGTIKVWDLETGELLrtlKGHTGPVRDVAASADGT---YLASGSSDKTIRLW 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 263 QflsmvLENNEKdwvrTRTFRNHTHDVRAVA--EITTAVVSGGMDTQLVVrplldkHEVKSsasklrkiqfphrslvsca 340
Cdd:cd00200 79 D-----LETGEC----VRTLTGHTSYVSSVAfsPDGRILSSSSRDKTIKV------WDVET------------------- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 341 rkaGTLLFQYPGHlelwrlgesegegipgsslllkrkpekllhlkvkgEDHIRCSAVSPCGEWIAYSTT-SSLRLYklhc 419
Cdd:cd00200 125 ---GKCLTTLRGH-----------------------------------TDWVNSVAFSPDGTFVASSSQdGTIKLW---- 162
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 420 dsNNVSITKISKLPKVLGSASQLCFSSDSTHLFSASTQSSVHMVSLSQPECkfVATFktkSGSHQAIHLLAASEDGKWLA 499
Cdd:cd00200 163 --DLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKC--LGTL---RGHENGVNSVAFSPDGYLLA 235
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 47086123 500 SANIDNEVHIYNLQTRKAHCTVPIYSSAVSAMAIHPTTNCLFMVHADQQI 549
Cdd:cd00200 236 SGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTI 285
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
21-131 |
2.41e-05 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 47.77 E-value: 2.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 21 ALAFNQHNERMAAAKMNGSVEIFHCSDRFFQEKII--PGREQAG---IEGLTW---VGERLFSAGLNGVITEYDLTNQRV 92
Cdd:PLN00181 488 AIGFDRDGEFFATAGVNKKIKIFECESIIKDGRDIhyPVVELASrskLSGICWnsyIKSQVASSNFEGVVQVWDVARSQL 567
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 47086123 93 KYTIDAYGGPIWAIT-GNQQGTHLAVGCEDGTVKLFEVTE 131
Cdd:PLN00181 568 VTEMKEHEKRVWSIDySSADPTLLASGSDDGSVKLWSINQ 607
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
115-201 |
9.41e-05 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 41.49 E-value: 9.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 115 LAVGCEDGTVKLFEVTEDKIqFERNLDRQKGRIISLSWHPSGSKIAAGMMD-MIQVFNVETGHSKHRILVDRGYGTsrgk 193
Cdd:pfam12894 10 IALATEDGELLLHRLNWQRV-WTLSPDKEDLEVTSLAWRPDGKLLAVGYSDgTVRLLDAENGKIVHHFSAGSDLIT---- 84
|
....*...
gi 47086123 194 eCVVWSVV 201
Cdd:pfam12894 85 -CLGWGEN 91
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
7-305 |
1.81e-28 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 118.09 E-value: 1.81e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 7 HRVRFFEYVPSGIRALAFNQHNERMAAAKMNGSVEIFHcsdrffqekIIPGREQAGIEGLT-WV--------GERLFSAG 77
Cdd:COG2319 111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWD---------LATGKLLRTLTGHSgAVtsvafspdGKLLASGS 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 78 LNGVITEYDLTNQRVKYTIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQfeRNLDRQKGRIISLSWHPSGS 157
Cdd:COG2319 182 DDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL--RTLTGHSGSVRSVAFSPDGR 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 158 KIAAGMMD-MIQVFNVETGHSKHRIlvdrgygtsRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLIKSHNITK 235
Cdd:COG2319 260 LLASGSADgTVRLWDLATGELLRTL---------TGHSGGVNSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHT 330
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 47086123 236 SDVLSLSVSQNEDSIVAGTSEGFVvqfqflsmvlenneKDW-----VRTRTFRNHTHDVRAVAeIT---TAVVSGGMD 305
Cdd:COG2319 331 GAVRSVAFSPDGKTLASGSDDGTV--------------RLWdlatgELLRTLTGHTGAVTSVA-FSpdgRTLASGSAD 393
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
17-305 |
7.50e-28 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 116.55 E-value: 7.50e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 17 SGIRALAFNQHNERMAAAKMNGSVEIFHCSDRffQEKIIPGREQAGIEGLTW--VGERLFSAGLNGVITEYDLTNQRVKY 94
Cdd:COG2319 79 AAVLSVAFSPDGRLLASASADGTVRLWDLATG--LLLRTLTGHTGAVRSVAFspDGKTLASGSADGTVRLWDLATGKLLR 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 95 TIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQfeRNLDRQKGRIISLSWHPSGSKIAAGMMD-MIQVFNVE 173
Cdd:COG2319 157 TLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLL--RTLTGHTGAVRSVAFSPDGKLLASGSADgTVRLWDLA 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 174 TGHSKHRIlvdrgygtsRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLIKSHNITKSDVLSLSVSQNEDSIVA 252
Cdd:COG2319 235 TGKLLRTL---------TGHSGSVRSVAFSPDGrLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLAS 305
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 47086123 253 GTSEGFVVQFQFlsmvlenneKDWVRTRTFRNHTHDVRAVA--EITTAVVSGGMD 305
Cdd:COG2319 306 GSDDGTVRLWDL---------ATGKLLRTLTGHTGAVRSVAfsPDGKTLASGSDD 351
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
70-514 |
5.37e-26 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 110.77 E-value: 5.37e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 70 GERLFSAGLNGVITEYDLTNQRVKYTIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQfeRNLDRQKGRIIS 149
Cdd:COG2319 48 GARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLL--RTLTGHTGAVRS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 150 LSWHPSGSKIAAGMMD-MIQVFNVETGHSKHRIlvdrgygtsRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTL 227
Cdd:COG2319 126 VAFSPDGKTLASGSADgTVRLWDLATGKLLRTL---------TGHSGAVTSVAFSPDGkLLASGSDDGTVRLWDLATGKL 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 228 IKSHNITKSDVLSLSVSQNEDSIVAGTSEGFVVQFQflsmvLENNEkdwvRTRTFRNHTHDVRAVAeIT---TAVVSGGM 304
Cdd:COG2319 197 LRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD-----LATGK----LLRTLTGHSGSVRSVA-FSpdgRLLASGSA 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 305 DtqlvvrplldkhevkssasklrkiqfphrslvscarkagtllfqypGHLELWRLgesegegipgsslllkrKPEKLLHL 384
Cdd:COG2319 267 D----------------------------------------------GTVRLWDL-----------------ATGELLRT 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 385 KVKGEDHIRCSAVSPCGEWIAY-STTSSLRLYKLHcdsnnvSITKISKLPKVLGSASQLCFSSDSTHLFSASTQSSVHMV 463
Cdd:COG2319 284 LTGHSGGVNSVAFSPDGKLLASgSDDGTVRLWDLA------TGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLW 357
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 47086123 464 SLSQPECKfvatfKTKSGSHQAIHLLAASEDGKWLASANIDNEVHIYNLQT 514
Cdd:COG2319 358 DLATGELL-----RTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
17-257 |
1.70e-25 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 109.23 E-value: 1.70e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 17 SGIRALAFNQHNERMAAAKMNGSVEIFHCSDrffqekiipGREQAGIEGLT-WV--------GERLFSAGLNGVITEYDL 87
Cdd:COG2319 163 GAVTSVAFSPDGKLLASGSDDGTVRLWDLAT---------GKLLRTLTGHTgAVrsvafspdGKLLASGSADGTVRLWDL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 88 TNQRVKYTIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQfeRNLDRQKGRIISLSWHPSGSKIAAGMMD-M 166
Cdd:COG2319 234 ATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELL--RTLTGHSGGVNSVAFSPDGKLLASGSDDgT 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 167 IQVFNVETGHSKHrilvdrgygTSRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLIKSHNITKSDVLSLSVSQ 245
Cdd:COG2319 312 VRLWDLATGKLLR---------TLTGHTGAVRSVAFSPDGkTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSP 382
|
250
....*....|..
gi 47086123 246 NEDSIVAGTSEG 257
Cdd:COG2319 383 DGRTLASGSADG 394
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
16-305 |
1.08e-20 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 92.78 E-value: 1.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 16 PSGIRALAFNQHNERMAAAKMNGSVEIFHCSDRFFQEkiipgREQAGIEGLTWV-----GERLFSAGLNGVITEYDLTNQ 90
Cdd:cd00200 9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLR-----TLKGHTGPVRDVaasadGTYLASGSSDKTIRLWDLETG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 91 RVKYTIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQFErnLDRQKGRIISLSWHPSGSKIAAGMMD-MIQV 169
Cdd:cd00200 84 ECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTT--LRGHTDWVNSVAFSPDGTFVASSSQDgTIKL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 170 FNVETGHSKHRIlvdrgygtsRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLIKSHNITKSDVLSLSVSQNED 248
Cdd:cd00200 162 WDLRTGKCVATL---------TGHTGEVNSVAFSPDGeKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGY 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 47086123 249 SIVAGTSEGFVVQFqflsmvlenNEKDWVRTRTFRNHTHDVRAVA--EITTAVVSGGMD 305
Cdd:cd00200 233 LLASGSEDGTIRVW---------DLRTGECVQTLSGHTNSVTSLAwsPDGKRLASGSAD 282
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
189-549 |
1.28e-17 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 85.73 E-value: 1.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 189 TSRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLIKSHNITKSDVLSLSVSQNEDSIVAGTSEGFVVQFqflsm 267
Cdd:COG2319 73 TLLGHTAAVLSVAFSPDGrLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLW----- 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 268 vlenNEKDWVRTRTFRNHTHDVRAVAeIT---TAVVSGGMDTQLVVRPLLDkhevkssasklrkiqfphrslvscarkaG 344
Cdd:COG2319 148 ----DLATGKLLRTLTGHSGAVTSVA-FSpdgKLLASGSDDGTVRLWDLAT----------------------------G 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 345 TLLFQYPGHlelwrlgesegegipgsslllkrkpekllhlkvkgEDHIRCSAVSPCGEWIAY-STTSSLRLYKLHcdsnn 423
Cdd:COG2319 195 KLLRTLTGH-----------------------------------TGAVRSVAFSPDGKLLASgSADGTVRLWDLA----- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 424 vSITKISKLPKVLGSASQLCFSSDSTHLFSASTQSSVHMVSLSQPECKfvatfKTKSGSHQAIHLLAASEDGKWLASANI 503
Cdd:COG2319 235 -TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELL-----RTLTGHSGGVNSVAFSPDGKLLASGSD 308
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 47086123 504 DNEVHIYNLQTRKAHCTVPIYSSAVSAMAIHPTTNCLFMVHADQQI 549
Cdd:COG2319 309 DGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTV 354
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
95-346 |
3.62e-15 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 76.60 E-value: 3.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 95 TIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKIQFernldRQKGRIISL---SWHPSGSKIAAGMMD-MIQVF 170
Cdd:cd00200 4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLR-----TLKGHTGPVrdvAASADGTYLASGSSDkTIRLW 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 171 NVETGHSKHRIlvdrgygtsRGKECVVWSVVYLSDGTIISGDSV-GMVKMWRDDTGTLIKSHNITKSDVLSLSVSQNEDS 249
Cdd:cd00200 79 DLETGECVRTL---------TGHTSYVSSVAFSPDGRILSSSSRdKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTF 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 250 IVAGTSEGFVVQFqflsmvlenNEKDWVRTRTFRNHTHDVRAVA--EITTAVVSGGMDTQLVVRPLLDKHEVKSSASKLR 327
Cdd:cd00200 150 VASSSQDGTIKLW---------DLRTGKCVATLTGHTGEVNSVAfsPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHEN 220
|
250 260
....*....|....*....|...
gi 47086123 328 KIQF----PHRSLVSCARKAGTL 346
Cdd:cd00200 221 GVNSvafsPDGYLLASGSEDGTI 243
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
196-535 |
6.57e-14 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 74.18 E-value: 6.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 196 VVWSVVYLSDGTIISGDSVGMVKMWRDDTGTLIKSHNITKSDVLSLSVSQNEDSIVAGTSEGFVVQFQFLSmvlennekd 275
Cdd:COG2319 39 VASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLAT--------- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 276 WVRTRTFRNHTHDVRAVAeIT---TAVVSGGMDTQLVVRPLLDkhevkssasklrkiqfphrslvscarkaGTLLFQYPG 352
Cdd:COG2319 110 GLLLRTLTGHTGAVRSVA-FSpdgKTLASGSADGTVRLWDLAT----------------------------GKLLRTLTG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 353 HlelwrlgesegegipgsslllkrkpekllhlkvkgEDHIRCSAVSPCGEWIAY-STTSSLRLYKLHcdsnnvSITKISK 431
Cdd:COG2319 161 H-----------------------------------SGAVTSVAFSPDGKLLASgSDDGTVRLWDLA------TGKLLRT 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 432 LPKVLGSASQLCFSSDSTHLFSASTQSSVHMVSLSQPECkfVATFKTKSGSHQAIhllAASEDGKWLASANIDNEVHIYN 511
Cdd:COG2319 200 LTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKL--LRTLTGHSGSVRSV---AFSPDGRLLASGSADGTVRLWD 274
|
330 340
....*....|....*....|....
gi 47086123 512 LQTRKAHCTVPIYSSAVSAMAIHP 535
Cdd:COG2319 275 LATGELLRTLTGHSGGVNSVAFSP 298
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
187-549 |
5.60e-12 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 66.97 E-value: 5.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 187 YGTSRGKECVVWSVVYLSDG-TIISGDSVGMVKMWRDDTGTLI---KSHNITKSDVLSLSVSQnedSIVAGTSEGFVVQF 262
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGkLLATGSGDGTIKVWDLETGELLrtlKGHTGPVRDVAASADGT---YLASGSSDKTIRLW 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 263 QflsmvLENNEKdwvrTRTFRNHTHDVRAVA--EITTAVVSGGMDTQLVVrplldkHEVKSsasklrkiqfphrslvsca 340
Cdd:cd00200 79 D-----LETGEC----VRTLTGHTSYVSSVAfsPDGRILSSSSRDKTIKV------WDVET------------------- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 341 rkaGTLLFQYPGHlelwrlgesegegipgsslllkrkpekllhlkvkgEDHIRCSAVSPCGEWIAYSTT-SSLRLYklhc 419
Cdd:cd00200 125 ---GKCLTTLRGH-----------------------------------TDWVNSVAFSPDGTFVASSSQdGTIKLW---- 162
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 420 dsNNVSITKISKLPKVLGSASQLCFSSDSTHLFSASTQSSVHMVSLSQPECkfVATFktkSGSHQAIHLLAASEDGKWLA 499
Cdd:cd00200 163 --DLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKC--LGTL---RGHENGVNSVAFSPDGYLLA 235
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 47086123 500 SANIDNEVHIYNLQTRKAHCTVPIYSSAVSAMAIHPTTNCLFMVHADQQI 549
Cdd:cd00200 236 SGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTI 285
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
17-221 |
2.09e-11 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 65.43 E-value: 2.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 17 SGIRALAFNQHNERMAAAKMNGSVEIFHcSDRFFQEKIIPGREqAGIEGLTW--VGERLFSAGLNGVITEYDLTNQRVKY 94
Cdd:cd00200 94 SYVSSVAFSPDGRILSSSSRDKTIKVWD-VETGKCLTTLRGHT-DWVNSVAFspDGTFVASSSQDGTIKLWDLRTGKCVA 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 95 TIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVTEDKiqFERNLDRQKGRIISLSWHPSGSKIAAGMMD-MIQVFNVE 173
Cdd:cd00200 172 TLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGK--CLGTLRGHENGVNSVAFSPDGYLLASGSEDgTIRVWDLR 249
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 47086123 174 TGHSKHRIlvdRGYGTSrgkecvVWSVVYLSDG-TIISGDSVGMVKMWR 221
Cdd:cd00200 250 TGECVQTL---SGHTNS------VTSLAWSPDGkRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
8-130 |
1.68e-08 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 57.23 E-value: 1.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 8 RVRFFEYVPSGIRALAFNQHNERMAAAKMNGSVEIFHCSDrffqekiipGREQAGIEGLTWV---------GERLFSAGL 78
Cdd:COG2319 280 LLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLAT---------GKLLRTLTGHTGAvrsvafspdGKTLASGSD 350
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 47086123 79 NGVITEYDLTNQRVKYTIDAYGGPIWAITGNQQGTHLAVGCEDGTVKLFEVT 130
Cdd:COG2319 351 DGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
437-558 |
1.51e-06 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 50.41 E-value: 1.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 437 GSASQLCFSSDSTHLFSASTQSSVHMVSLSQPECKFvaTFKTKSGShqaIHLLAASEDGKWLASANIDNEVHIYNLQTRK 516
Cdd:cd00200 10 GGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLR--TLKGHTGP---VRDVAASADGTYLASGSSDKTIRLWDLETGE 84
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 47086123 517 AHCTVPIYSSAVSAMAIHPTTNCLFMVHADQQIFEFSIEQKE 558
Cdd:cd00200 85 CVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGK 126
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
21-131 |
2.41e-05 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 47.77 E-value: 2.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 21 ALAFNQHNERMAAAKMNGSVEIFHCSDRFFQEKII--PGREQAG---IEGLTW---VGERLFSAGLNGVITEYDLTNQRV 92
Cdd:PLN00181 488 AIGFDRDGEFFATAGVNKKIKIFECESIIKDGRDIhyPVVELASrskLSGICWnsyIKSQVASSNFEGVVQVWDVARSQL 567
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 47086123 93 KYTIDAYGGPIWAIT-GNQQGTHLAVGCEDGTVKLFEVTE 131
Cdd:PLN00181 568 VTEMKEHEKRVWSIDySSADPTLLASGSDDGSVKLWSINQ 607
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
115-201 |
9.41e-05 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 41.49 E-value: 9.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 115 LAVGCEDGTVKLFEVTEDKIqFERNLDRQKGRIISLSWHPSGSKIAAGMMD-MIQVFNVETGHSKHRILVDRGYGTsrgk 193
Cdd:pfam12894 10 IALATEDGELLLHRLNWQRV-WTLSPDKEDLEVTSLAWRPDGKLLAVGYSDgTVRLLDAENGKIVHHFSAGSDLIT---- 84
|
....*...
gi 47086123 194 eCVVWSVV 201
Cdd:pfam12894 85 -CLGWGEN 91
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
392-555 |
9.72e-04 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 41.55 E-value: 9.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 392 IRCSAVSPCGEWIAystTSS----LRLYKLhcDSNNVSITKISKLPKVLGSAsqlcFSSDSTHLFSASTQSSVHMVSLSQ 467
Cdd:cd00200 12 VTCVAFSPDGKLLA---TGSgdgtIKVWDL--ETGELLRTLKGHTGPVRDVA----ASADGTYLASGSSDKTIRLWDLET 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086123 468 PECkfVATFKtksGSHQAIHLLAASEDGKWLASANIDNEVHIYNLQTRKAHCTVPIYSSAVSAMAIHPTTNCLFMVHADQ 547
Cdd:cd00200 83 GEC--VRTLT---GHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDG 157
|
....*...
gi 47086123 548 QIFEFSIE 555
Cdd:cd00200 158 TIKLWDLR 165
|
|
| |
