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Conserved domains on  [gi|489318178|ref|WP_003225531|]
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MULTISPECIES: anthranilate phosphoribosyltransferase [Bacillus subtilis group]

Protein Classification

anthranilate phosphoribosyltransferase( domain architecture ID 11478311)

anthranilate phosphoribosyltransferase catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)

Gene Ontology:  GO:0004048|GO:0000162|GO:0046872
PubMed:  36633281|28844746
SCOP:  4003843|4000984

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
trpD PRK00188
anthranilate phosphoribosyltransferase; Provisional
 1-331 2.23e-175

anthranilate phosphoribosyltransferase; Provisional


:

Pssm-ID: 234682 [Multi-domain]  Cd Length: 339  Bit Score: 489.59  E-value: 2.23e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   1 MNKFLQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVDGLPDVVDTCGTG 80
Cdd:PRK00188   3 MKELLEKLVEGEDLSEEEAEELMDAIMSGEATPAQIAAFLTALRVKGETVDEIAGAARAMREHAVPVPDPDDAVDIVGTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  81 GDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKHV 160
Cdd:PRK00188  83 GDGANTFNISTAAAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEVGIGFLFAPLYHPAMKHV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 161 AGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDGE 240
Cdd:PRK00188 163 APVRKELGIRTIFNLLGPLTNPARPKRQLIGVYSPDLLEPMAEVLKRLGSKRALVVHGSDGLDEISLTGPTTVAELKDGE 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 241 RREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGITASLKEGTELALETITSG 320
Cdd:PRK00188 243 IREYTLTPEDFGLPRAPLEDLRGGDPEENAAILRAVLQGKGPGAARDAVLLNAAAALYVAGKADDLKEGVELAREAIDSG 322

                        330
                 ....*....|.
gi 489318178 321 GAAAQLERLKQ 331
Cdd:PRK00188 323 AALAKLEELVA 333
 
Name Accession Description Interval E-value
trpD PRK00188
anthranilate phosphoribosyltransferase; Provisional
 1-331 2.23e-175

anthranilate phosphoribosyltransferase; Provisional


Pssm-ID: 234682 [Multi-domain]  Cd Length: 339  Bit Score: 489.59  E-value: 2.23e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   1 MNKFLQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVDGLPDVVDTCGTG 80
Cdd:PRK00188   3 MKELLEKLVEGEDLSEEEAEELMDAIMSGEATPAQIAAFLTALRVKGETVDEIAGAARAMREHAVPVPDPDDAVDIVGTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  81 GDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKHV 160
Cdd:PRK00188  83 GDGANTFNISTAAAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEVGIGFLFAPLYHPAMKHV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 161 AGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDGE 240
Cdd:PRK00188 163 APVRKELGIRTIFNLLGPLTNPARPKRQLIGVYSPDLLEPMAEVLKRLGSKRALVVHGSDGLDEISLTGPTTVAELKDGE 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 241 RREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGITASLKEGTELALETITSG 320
Cdd:PRK00188 243 IREYTLTPEDFGLPRAPLEDLRGGDPEENAAILRAVLQGKGPGAARDAVLLNAAAALYVAGKADDLKEGVELAREAIDSG 322

                        330
                 ....*....|.
gi 489318178 321 GAAAQLERLKQ 331
Cdd:PRK00188 323 AALAKLEELVA 333
trpD TIGR01245
anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, ...
 5-331 7.56e-169

anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, Thermotoga maritima, and Archaeoglobus fulgidus, this enzymatic domain (anthranilate phosphoribosyltransferase) is found C-terminal to glutamine amidotransferase; the fusion protein is designated anthranilate synthase component II (EC 4.1.3.27) [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 273522 [Multi-domain]  Cd Length: 330  Bit Score: 472.91  E-value: 7.56e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178    5 LQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVDGLP--DVVDTCGTGGD 82
Cdd:TIGR01245   1 LEKLIDGKDLSRDEAEQLMKEIMSGEASPAQIAAILTALRIKGETPEEITGFAKAMREHAVKVPGRPpeDLVDIVGTGGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   83 GISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKHVAG 162
Cdd:TIGR01245  81 GANTINISTASAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLGPEKVARSLEETGIGFLFAPLYHPAMKHVAP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  163 TRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDGERR 242
Cdd:TIGR01245 161 VRRELGVRTVFNLLGPLTNPARPKYQVIGVYDPDLVEVMAEALKNLGVKRALVVHGDDGLDEISLTGPTTVAELKDGEIR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  243 EYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGITASLKEGTELALETITSGGA 322
Cdd:TIGR01245 241 EYTLDPEDFGLPRAPLEELAGGSPEENAEILRDILRGKGSGAKRDIVALNAAAALYVAGRASDLKEGVELALEAIDSGAA 320


                  ....*....
gi 489318178  323 AAQLERLKQ 331
Cdd:TIGR01245 321 AEKLEELVA 329
TrpD COG0547
Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and ...
 1-326 3.36e-158

Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and metabolism]; Anthranilate phosphoribosyltransferase, glycosyltransferase domain is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440313 [Multi-domain]  Cd Length: 327  Bit Score: 445.68  E-value: 3.36e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   1 MNKFLQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVD-GLPDVVDTCGT 79
Cdd:COG0547    2 MKELLKKLAEGKDLTREEAREAMRQIMSGEATPAQIGAFLTALRMKGETVEEIAGFADAMRELAVPVPlPDGDVVDIVGT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  80 GGDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKH 159
Cdd:COG0547   82 GGDGANTFNISTAAAFVAAAAGVPVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEAGIGFLFAPLFHPAMKH 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 160 VAGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDG 239
Cdd:COG0547  162 VAPVRKELGVRTIFNLLGPLTNPAGPKRQLLGVYHPELVEPLAEVLQLLGVKRALVVHGLDGLDEISLTGPTKVAELRDG 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 240 ERREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKsSSSALSITAFNAGAAIYTAGITASLKEGTELALETITS 319
Cdd:COG0547  242 EIEEYTLDPEDFGLPRAPLEDLRGGDAEENAEILRAVLAGE-GGPARDAVLLNAAAALYVAGKADSLAEGVELAREAIDS 320


                 ....*..
gi 489318178 320 GGAAAQL 326
Cdd:COG0547  321 GAALAKL 327
Glycos_transf_3 pfam00591
Glycosyl transferase family, a/b domain; This family includes anthranilate ...
 70-323 3.22e-123

Glycosyl transferase family, a/b domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 459860 [Multi-domain]  Cd Length: 253  Bit Score: 354.29  E-value: 3.22e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   70 LPDVVDTCGTGGDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLF 149
Cdd:pfam00591   1 LGDLVDIVGTGGDGDNTFNISTAAAIVAAACGVKVAKHGNRSVSSKSGSADVLEALGINLDLTPEQVRKLLDEVGVGFLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  150 APLYHSSMKHVAGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSrDGLDELSITA 229
Cdd:pfam00591  81 APNYHPAMKHVAPVRRELGIRTVFNLLGPLINPARVKRQVLGVYSKELAEGLAEVLKDLGRERAAVVHG-DGLDEASLLG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  230 PTDVIELKDGERREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGITASLKEG 309
Cdd:pfam00591 160 KTTVAELKDGEITEYTLTPEDFGLGRATLEALEGGSPKENADILKGVLGGKGSAAHRDLVALNAGAALYLAGKADSLKEG 239

                         250
                  ....*....|....
gi 489318178  310 TELALETITSGGAA 323
Cdd:pfam00591 240 VAKALEVIDSGKAL 253
 
Name Accession Description Interval E-value
trpD PRK00188
anthranilate phosphoribosyltransferase; Provisional
 1-331 2.23e-175

anthranilate phosphoribosyltransferase; Provisional


Pssm-ID: 234682 [Multi-domain]  Cd Length: 339  Bit Score: 489.59  E-value: 2.23e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   1 MNKFLQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVDGLPDVVDTCGTG 80
Cdd:PRK00188   3 MKELLEKLVEGEDLSEEEAEELMDAIMSGEATPAQIAAFLTALRVKGETVDEIAGAARAMREHAVPVPDPDDAVDIVGTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  81 GDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKHV 160
Cdd:PRK00188  83 GDGANTFNISTAAAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEVGIGFLFAPLYHPAMKHV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 161 AGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDGE 240
Cdd:PRK00188 163 APVRKELGIRTIFNLLGPLTNPARPKRQLIGVYSPDLLEPMAEVLKRLGSKRALVVHGSDGLDEISLTGPTTVAELKDGE 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 241 RREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGITASLKEGTELALETITSG 320
Cdd:PRK00188 243 IREYTLTPEDFGLPRAPLEDLRGGDPEENAAILRAVLQGKGPGAARDAVLLNAAAALYVAGKADDLKEGVELAREAIDSG 322

                        330
                 ....*....|.
gi 489318178 321 GAAAQLERLKQ 331
Cdd:PRK00188 323 AALAKLEELVA 333
trpD TIGR01245
anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, ...
 5-331 7.56e-169

anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, Thermotoga maritima, and Archaeoglobus fulgidus, this enzymatic domain (anthranilate phosphoribosyltransferase) is found C-terminal to glutamine amidotransferase; the fusion protein is designated anthranilate synthase component II (EC 4.1.3.27) [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 273522 [Multi-domain]  Cd Length: 330  Bit Score: 472.91  E-value: 7.56e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178    5 LQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVDGLP--DVVDTCGTGGD 82
Cdd:TIGR01245   1 LEKLIDGKDLSRDEAEQLMKEIMSGEASPAQIAAILTALRIKGETPEEITGFAKAMREHAVKVPGRPpeDLVDIVGTGGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   83 GISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKHVAG 162
Cdd:TIGR01245  81 GANTINISTASAFVAAAAGVKVAKHGNRSVSSKSGSADVLEALGVNLDLGPEKVARSLEETGIGFLFAPLYHPAMKHVAP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  163 TRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDGERR 242
Cdd:TIGR01245 161 VRRELGVRTVFNLLGPLTNPARPKYQVIGVYDPDLVEVMAEALKNLGVKRALVVHGDDGLDEISLTGPTTVAELKDGEIR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  243 EYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGITASLKEGTELALETITSGGA 322
Cdd:TIGR01245 241 EYTLDPEDFGLPRAPLEELAGGSPEENAEILRDILRGKGSGAKRDIVALNAAAALYVAGRASDLKEGVELALEAIDSGAA 320


                  ....*....
gi 489318178  323 AAQLERLKQ 331
Cdd:TIGR01245 321 AEKLEELVA 329
TrpD COG0547
Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and ...
 1-326 3.36e-158

Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and metabolism]; Anthranilate phosphoribosyltransferase, glycosyltransferase domain is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440313 [Multi-domain]  Cd Length: 327  Bit Score: 445.68  E-value: 3.36e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   1 MNKFLQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVD-GLPDVVDTCGT 79
Cdd:COG0547    2 MKELLKKLAEGKDLTREEAREAMRQIMSGEATPAQIGAFLTALRMKGETVEEIAGFADAMRELAVPVPlPDGDVVDIVGT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  80 GGDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKH 159
Cdd:COG0547   82 GGDGANTFNISTAAAFVAAAAGVPVAKHGNRSVSSKSGSADVLEALGVNLDLSPEQVARCLEEAGIGFLFAPLFHPAMKH 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 160 VAGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDG 239
Cdd:COG0547  162 VAPVRKELGVRTIFNLLGPLTNPAGPKRQLLGVYHPELVEPLAEVLQLLGVKRALVVHGLDGLDEISLTGPTKVAELRDG 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 240 ERREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKsSSSALSITAFNAGAAIYTAGITASLKEGTELALETITS 319
Cdd:COG0547  242 EIEEYTLDPEDFGLPRAPLEDLRGGDAEENAEILRAVLAGE-GGPARDAVLLNAAAALYVAGKADSLAEGVELAREAIDS 320


                 ....*..
gi 489318178 320 GGAAAQL 326
Cdd:COG0547  321 GAALAKL 327
Glycos_transf_3 pfam00591
Glycosyl transferase family, a/b domain; This family includes anthranilate ...
 70-323 3.22e-123

Glycosyl transferase family, a/b domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 459860 [Multi-domain]  Cd Length: 253  Bit Score: 354.29  E-value: 3.22e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   70 LPDVVDTCGTGGDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLF 149
Cdd:pfam00591   1 LGDLVDIVGTGGDGDNTFNISTAAAIVAAACGVKVAKHGNRSVSSKSGSADVLEALGINLDLTPEQVRKLLDEVGVGFLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  150 APLYHSSMKHVAGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSrDGLDELSITA 229
Cdd:pfam00591  81 APNYHPAMKHVAPVRRELGIRTVFNLLGPLINPARVKRQVLGVYSKELAEGLAEVLKDLGRERAAVVHG-DGLDEASLLG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  230 PTDVIELKDGERREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGITASLKEG 309
Cdd:pfam00591 160 KTTVAELKDGEITEYTLTPEDFGLGRATLEALEGGSPKENADILKGVLGGKGSAAHRDLVALNAGAALYLAGKADSLKEG 239

                         250
                  ....*....|....
gi 489318178  310 TELALETITSGGAA 323
Cdd:pfam00591 240 VAKALEVIDSGKAL 253
PRK14607 PRK14607
bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase;
9-330 2.16e-122

bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase;


Pssm-ID: 237764 [Multi-domain]  Cd Length: 534  Bit Score: 362.11  E-value: 2.16e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   9 VDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVDG-LPDVVDTCGTGGDGISTF 87
Cdd:PRK14607 203 VEGEDLSFEEAEDVMEDITDGNATDAQIAGFLTALRMKGETADELAGFASVMREKSRHIPApSPRTVDTCGTGGDGFGTF 282

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  88 NISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKHVAGTRKEL 167
Cdd:PRK14607 283 NISTTSAFVVAAAGVPVAKHGNRAVSSKSGSADVLEALGVKLEMTPEEAASVLRETGFSFLFAPLFHPAMKHAAPARREL 362

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 168 GFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDGERREYTVS 247
Cdd:PRK14607 363 GIRTAFNLLGPLTNPARVKYQIVGVFDPSYAEPLAQALQRLGTERAMVVSGIDGYDEISTCGPTQILELEDGEIVTYTFD 442

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 248 PEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGITASLKEGTELALETITSGGAAAQLE 327
Cdd:PRK14607 443 PEELGLKRVDPEELKGGDPQENYRLAEDVLKGEPRRPQRDAVALNAGAALYLVGEADSIKEGVGKALDLIDDGRAYKKLE 522


                 ...
gi 489318178 328 RLK 330
Cdd:PRK14607 523 EVM 525
PLN02641 PLN02641
anthranilate phosphoribosyltransferase
 1-328 8.53e-103

anthranilate phosphoribosyltransferase


Pssm-ID: 215345 [Multi-domain]  Cd Length: 343  Bit Score: 305.50  E-value: 8.53e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   1 MNKFLQLCVDGKTLTADEAEALMNMMItAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVDGLPDVVDTCGTG 80
Cdd:PLN02641   4 FRQLIESLIQGTDLTEEEAEAALDFLL-DDADEAQISAFLVLLRAKGETFEEIAGLARAMIKRARKVDGLVDAVDIVGTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  81 GDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMKHV 160
Cdd:PLN02641  83 GDGANTVNISTGSSILAAACGAKVAKQGNRSSSSACGSADVLEALGVAIDLGPEGVKRCVEEVGIGFMMAPKYHPAMKIV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 161 AGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSRdGLDELSITAPTDVIELKDGE 240
Cdd:PLN02641 163 APVRKKLKVKTVFNILGPMLNPARVPHAVVGVYHESLVEKMAKALQRFGMKRALVVHSE-GLDEMSPLGPGDVLEVTPEK 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 241 RREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITaFNAGAAIYTAGITASLKEGTELALETITSG 320
Cdd:PLN02641 242 IEEFSFDPLDFGIPRCTLEDLRGGDPDYNAKVLRDVLSGEKGAIADALI-LNAAAALLVSGLAKTLAEGVALARETQESG 320


                 ....*...
gi 489318178 321 GAAAQLER 328
Cdd:PLN02641 321 KAIKTLDS 328
PRK09522 PRK09522
bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate ...
 1-322 1.03e-65

bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD;


Pssm-ID: 181927 [Multi-domain]  Cd Length: 531  Bit Score: 216.05  E-value: 1.03e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   1 MNKFLQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARALTVDgLPD--VVDTCG 78
Cdd:PRK09522 200 LQPILEKLYQAQTLSQQESHQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFP-RPDylFADIVG 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  79 TGGDGISTFNISTASAIVASAAGAKIAKHGNRSVSSKSGSADVLEVLEVPIQTTPEKVKSSIEANNMGFLFAPLYHSSMK 158
Cdd:PRK09522 279 TGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNADKSRQALDELGVCFLFAPKYHTGFR 358

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 159 HVAGTRKELGFRTVFNLLGPLSNPLQAKRQVIGVYSAEKAGLMASALETFQPKHVMFVSSrDGLDELSITAPTDVIELKD 238
Cdd:PRK09522 359 HAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHS-GGMDEVSLHAPTIVAELHD 437

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 239 GERREYTVSPEAFGFTNGRLEDLQVESPKESACLIQNIFENKSSSSALSITAFNAGAAIYTAGiTASLKEGTELALETIT 318
Cdd:PRK09522 438 GEIKSYQLTAEDFGLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHG-HEDLQANAQTVLEVLR 516


                 ....
gi 489318178 319 SGGA 322
Cdd:PRK09522 517 SGSA 520
PRK09071 PRK09071
glycosyl transferase family protein;
11-264 1.19e-20

glycosyl transferase family protein;


Pssm-ID: 181637 [Multi-domain]  Cd Length: 323  Bit Score: 90.74  E-value: 1.19e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  11 GKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRAR----ALTVD-----------GLPDVVd 75
Cdd:PRK09071  18 RRSLTREEARQAMGMILDGEVEDDQLGAFLMLLRVKEETAEELAGFVEAIRERlqapPLAVDldwpsyagkrrHLPWYL- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  76 tcgtggdgistfnisTASAIVAsAAGAKIAKHGNRSVSSKSGSA-DVLEVLEVPIQTTPEKVKSSIEANNMGFLfaPL-- 152
Cdd:PRK09071  97 ---------------LAAKLLA-QNGYRVLLHGGGGHTAGRLYTeQLLEALGIPIARSWQEAEQALEEHNIAYL--PLed 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 153 YHSSMKHVAGTRKELGFRTVFNLLGPLSNPLQAkrqvigvysaeKAGLMASALETFQPKHvmfvssRDGLDELsitAPTD 232
Cdd:PRK09071 159 FAPQLQRMIDLRNTLGLRSPINTLARLLNPLNA-----------KASLQGIFHPGYQQLH------REAARLL---GDQN 218

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 489318178 233 VIELKdGERREYTVSPEA----FGFTNGRLEDLQVE 264
Cdd:PRK09071 219 ALVFK-GEGGESERNPDVsttlYGSRNGEAWDEEWP 253
PRK07394 PRK07394
hypothetical protein; Provisional
 11-331 1.92e-20

hypothetical protein; Provisional


Pssm-ID: 168934 [Multi-domain]  Cd Length: 342  Bit Score: 90.36  E-value: 1.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  11 GKTLTADEAEALMNMMITAEMAPSEMGGILsiLAHRGE--TPEELTGFVKAMRARA--LTVDGLPDVVDTCGTGGDGIS- 85
Cdd:PRK07394  19 SKDLTREEAADALKLMLLGEATPAQIGAFL--IAHRIKrpTPEELAGMLDTYDELGpkLQSPSNQRPPIVFGMPYDGRSr 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178  86 TFNISTASAIVASAAGAKIAKHGNRSVSSKSG--SADVLEVLEVPIQTTP-EKVKSSIEANNMGFLFAPLYHSSMKHVAG 162
Cdd:PRK07394  97 TAPIYPLTALILAAAGQPVVLHGGDRMPTKYGvpLVELWQGLGVDLTGLSlEQVQEGFEQTGLAFIYQPDHFPLAESLIP 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 163 TRKELGFRTVFNLLGPLSNPLQAK-RQVIGVYSAEKAGLMASALETFQPKHVMFVSSRDGLDELSITAPTDVIELKDGER 241
Cdd:PRK07394 177 YRDEIGKRPPLATLELIWTPHQGDhHLVSGFVHPPTEARAWEALELRGETNFTTVKGLEGSCDLPISRTAIIGRVQNGHF 256

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178 242 REYTVSPEAFGFTNgrlEDLQVESPKESACLIQNIFENKSS---SSALsitaFNAGAAIYTAGITASLKEGTELALETIT 318
Cdd:PRK07394 257 ERLILHPRDYGCGG---KDVPWESTEEWLEQAQAALNGEPGpltQALI----WNGGFYLWRAGISSSLEEGIEKAEELLN 329

                        330
                 ....*....|...
gi 489318178 319 SGGAAAQLERLKQ 331
Cdd:PRK07394 330 SGKALQKLQQLIA 342
Glycos_trans_3N pfam02885
Glycosyl transferase family, helical bundle domain; This family includes anthranilate ...
 3-64 2.65e-15

Glycosyl transferase family, helical bundle domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 460737 [Multi-domain]  Cd Length: 63  Bit Score: 69.33  E-value: 2.65e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489318178    3 KFLQLCVDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRARA 64
Cdd:pfam02885   2 ELIKKLRDGEDLTREEARAAMDGIMSGEATDAQIAAFLMALRMKGETAEEIAGLARAMRESG 63
PRK08136 PRK08136
glycosyl transferase family protein; Provisional
 14-68 2.92e-07

glycosyl transferase family protein; Provisional


Pssm-ID: 236160 [Multi-domain]  Cd Length: 317  Bit Score: 51.40  E-value: 2.92e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489318178  14 LTADEAEALMNMMITAEMAPSEMGGILsiLAHR--GETPEELTGFVKAMRARALTVD 68
Cdd:PRK08136  20 LDRDTARALYGAMLDGRVPDLELGAIL--IALRikGESEAEMLGFLDAMQAHTIPLT 74
PRK04350 PRK04350
thymidine phosphorylase; Provisional
 9-125 8.58e-03

thymidine phosphorylase; Provisional


Pssm-ID: 235289 [Multi-domain]  Cd Length: 490  Bit Score: 37.87  E-value: 8.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489318178   9 VDGKTLTADEAEALMNMMITAEMAPSEMGGILSILAHRGETPEELTGFVKAMRA--------RALTVD-----GLPdvvd 75
Cdd:PRK04350  89 IDGEKLDKEEIEAIIRDIVAGRYSDIELSAFLTASAINGLDMDEIEALTRAMVEtgerldwdRPPVVDkhsigGVP---- 164

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 489318178  76 tcgtgGDGISTFNIstasAIVAsAAGAKIAKHGNRSVSSKSGSADVLEVL 125
Cdd:PRK04350 165 -----GNRTTLIVV----PIVA-AAGLTIPKTSSRAITSPAGTADTMEVL 204
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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