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Conserved domains on  [gi|124804166|ref|XP_001347921|]
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13 kDa ribonucleoprotein-associated protein, putative [Plasmodium falciparum 3D7]

Protein Classification

ribosomal eL8 family protein( domain architecture ID 1903236)

ribosomal eL8 family protein such as large ribosomal subunit protein eL8 and H/ACA ribonucleoprotein complex subunit 2

Gene Ontology:  GO:0003723
SCOP:  4001513

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SNU13 super family cl42391
U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, ...
 24-145 1.20e-70

U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, also known as NHP2-like protein 1 or U4/U6.U5 tri-snRNP 15.5 kDa protein, is a component of the spliceosome B complex, involved in pre-mRNA splicing. It binds to the 5'-stem-loop of U4 snRNA.


The actual alignment was detected with superfamily member cd21104:

Pssm-ID: 455736  Cd Length: 122  Bit Score: 207.95  E-value: 1.20e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166  24 NAKIFPLASPELTNQILDVIQRATVYRQLKRGANEAVKSLHKGISELVVLAADAKPLEIISHIPLVCEDKNTPYVYVRSK 103
Cdd:cd21104    1 NPKAYPLADAQLTQTILDLVQQAANYKQLKKGANEATKTLNRGIAEFIVMAADAEPLEILLHLPLLCEDKNVPYVFVPSK 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 124804166 104 MALGRACGISRSVIATSIVTKDGSPLETQITELKDLIEQMLI 145
Cdd:cd21104   81 QALGRACGVSRPVIACSVTTNEGSQLKSQIQSLKDAIEKLLI 122
 
Name Accession Description Interval E-value
SNU13 cd21104
U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, ...
 24-145 1.20e-70

U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, also known as NHP2-like protein 1 or U4/U6.U5 tri-snRNP 15.5 kDa protein, is a component of the spliceosome B complex, involved in pre-mRNA splicing. It binds to the 5'-stem-loop of U4 snRNA.


Pssm-ID: 411046  Cd Length: 122  Bit Score: 207.95  E-value: 1.20e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166  24 NAKIFPLASPELTNQILDVIQRATVYRQLKRGANEAVKSLHKGISELVVLAADAKPLEIISHIPLVCEDKNTPYVYVRSK 103
Cdd:cd21104    1 NPKAYPLADAQLTQTILDLVQQAANYKQLKKGANEATKTLNRGIAEFIVMAADAEPLEILLHLPLLCEDKNVPYVFVPSK 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 124804166 104 MALGRACGISRSVIATSIVTKDGSPLETQITELKDLIEQMLI 145
Cdd:cd21104   81 QALGRACGVSRPVIACSVTTNEGSQLKSQIQSLKDAIEKLLI 122
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 38-128 1.09e-24

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 90.73  E-value: 1.09e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166   38 QILDVIQRATVYRQLKRGANEAVKSLHKGISELVVLAADAKPLEIISHIPLVCEDKNTPYVYVRSKMALGRACGISRSVI 117
Cdd:pfam01248   2 AIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRPVS 81

                          90
                  ....*....|.
gi 124804166  118 ATSIVTKDGSP 128
Cdd:pfam01248  82 ALAIKDEGDSK 92
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 37-126 8.79e-16

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 67.88  E-value: 8.79e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166  37 NQILDVIQRATVYRQLKRGANEAVKSLHKGISELVVLAADAKPlEIISHIPLVCEDKNTPYVYVRSKMALGRACGIS-RS 115
Cdd:COG1358    1 DKILNLLGLARRAGKLVSGEEQVLKAIRKGKAKLVIIAEDASE-NTKKKLLDLCEEYGVPVVEVGTKEELGKAIGKVgRA 79

                         90
                 ....*....|.
gi 124804166 116 VIAtsiVTKDG 126
Cdd:COG1358   80 VVA---ITDEG 87
PRK13602 PRK13602
50S ribosomal protein L7ae-like protein;
55-112 7.16e-07

50S ribosomal protein L7ae-like protein;


Pssm-ID: 184174 [Multi-domain]  Cd Length: 82  Bit Score: 44.39  E-value: 7.16e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 124804166  55 GANEAVKSLHKGISELVVLAADAKPlEIISHIPLVCEDKNTPYVYVRSKMALGRACGI 112
Cdd:PRK13602  15 GTKQTVKALKRGSVKEVVVAEDADP-RLTEKVEALANEKGVPVSKVDSMKKLGKACGI 71
 
Name Accession Description Interval E-value
SNU13 cd21104
U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, ...
 24-145 1.20e-70

U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, also known as NHP2-like protein 1 or U4/U6.U5 tri-snRNP 15.5 kDa protein, is a component of the spliceosome B complex, involved in pre-mRNA splicing. It binds to the 5'-stem-loop of U4 snRNA.


Pssm-ID: 411046  Cd Length: 122  Bit Score: 207.95  E-value: 1.20e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166  24 NAKIFPLASPELTNQILDVIQRATVYRQLKRGANEAVKSLHKGISELVVLAADAKPLEIISHIPLVCEDKNTPYVYVRSK 103
Cdd:cd21104    1 NPKAYPLADAQLTQTILDLVQQAANYKQLKKGANEATKTLNRGIAEFIVMAADAEPLEILLHLPLLCEDKNVPYVFVPSK 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 124804166 104 MALGRACGISRSVIATSIVTKDGSPLETQITELKDLIEQMLI 145
Cdd:cd21104   81 QALGRACGVSRPVIACSVTTNEGSQLKSQIQSLKDAIEKLLI 122
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 38-128 1.09e-24

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 90.73  E-value: 1.09e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166   38 QILDVIQRATVYRQLKRGANEAVKSLHKGISELVVLAADAKPLEIISHIPLVCEDKNTPYVYVRSKMALGRACGISRSVI 117
Cdd:pfam01248   2 AIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRPVS 81

                          90
                  ....*....|.
gi 124804166  118 ATSIVTKDGSP 128
Cdd:pfam01248  82 ALAIKDEGDSK 92
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 37-126 8.79e-16

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 67.88  E-value: 8.79e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166  37 NQILDVIQRATVYRQLKRGANEAVKSLHKGISELVVLAADAKPlEIISHIPLVCEDKNTPYVYVRSKMALGRACGIS-RS 115
Cdd:COG1358    1 DKILNLLGLARRAGKLVSGEEQVLKAIRKGKAKLVIIAEDASE-NTKKKLLDLCEEYGVPVVEVGTKEELGKAIGKVgRA 79

                         90
                 ....*....|.
gi 124804166 116 VIAtsiVTKDG 126
Cdd:COG1358   80 VVA---ITDEG 87
PRK13602 PRK13602
50S ribosomal protein L7ae-like protein;
55-112 7.16e-07

50S ribosomal protein L7ae-like protein;


Pssm-ID: 184174 [Multi-domain]  Cd Length: 82  Bit Score: 44.39  E-value: 7.16e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 124804166  55 GANEAVKSLHKGISELVVLAADAKPlEIISHIPLVCEDKNTPYVYVRSKMALGRACGI 112
Cdd:PRK13602  15 GTKQTVKALKRGSVKEVVVAEDADP-RLTEKVEALANEKGVPVSKVDSMKKLGKACGI 71
PTZ00222 PTZ00222
60S ribosomal protein L7a; Provisional
 55-133 2.43e-06

60S ribosomal protein L7a; Provisional


Pssm-ID: 140249  Cd Length: 263  Bit Score: 45.46  E-value: 2.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166  55 GANEAVKSLHKGISELVVLAADAKPLEIISHIPLVCEDKNTPYVYVRSKMALGRACG--ISRSVIATSIVTKDGSPLETQ 132
Cdd:PTZ00222 136 GLQEVTRAIEKKQARMVVIANNVDPVELVLWMPNLCRANKIPYAIVKDMARLGDAIGrkTATCVAITDVNAEDEAALKNL 215


                 .
gi 124804166 133 I 133
Cdd:PTZ00222 216 I 216
PTZ00365 PTZ00365
60S ribosomal protein L7Ae-like; Provisional
 52-125 2.57e-06

60S ribosomal protein L7Ae-like; Provisional


Pssm-ID: 240382  Cd Length: 266  Bit Score: 45.22  E-value: 2.57e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124804166  52 LKRGANEAVKSLHKGISELVVLAADAKPLEIISHIPLVCEDKNTPYVYVRSKMALGRACG-ISRSVIATSIVTKD 125
Cdd:PTZ00365 133 LKYGLNHVTDLVEYKKAKLVVIAHDVDPIELVCFLPALCRKKEVPYCIIKGKSRLGKLVHqKTAAVVAIDNVRKE 207
RPL30E COG1911
Ribosomal protein L30E [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
 55-122 1.33e-05

Ribosomal protein L30E [Translation, ribosomal structure and biogenesis]; Ribosomal protein L30E is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441515 [Multi-domain]  Cd Length: 97  Bit Score: 41.35  E-value: 1.33e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 124804166  55 GANEAVKSLHKGISELVVLAADAkPLEIISHIPLVCEDKNTP-YVYVRSKMALGRACGISRSVIATSIV 122
Cdd:COG1911   20 GSKQTIKAIKLGKAKLVILAANC-PPEIREDIEYYAKLSNVPvYVYPGTSVELGALCGKPFRVSALAII 87
PRK01018 PRK01018
50S ribosomal protein L30e; Reviewed
 55-137 1.02e-04

50S ribosomal protein L30e; Reviewed


Pssm-ID: 179205 [Multi-domain]  Cd Length: 99  Bit Score: 39.18  E-value: 1.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124804166  55 GANEAVKSLHKGISELVVLAADAkPLEIISHIPLVCEDKNTP-YVYVRSKMALGRACGISRSVIATSIVtkdgSPLETQI 133
Cdd:PRK01018  20 GSKRTIKAIKLGKAKLVIVASNC-PKDIKEDIEYYAKLSGIPvYEYEGSSVELGTLCGKPFTVSALAIV----DPGESDI 94


                 ....
gi 124804166 134 TELK 137
Cdd:PRK01018  95 LELI 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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