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Conserved domains on  [gi|254569000|ref|XP_002491610|]
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Mitochondrial ribosomal protein of the small subunit [Komagataella phaffii GS115]

Protein Classification

uS17 family ribosomal protein( domain architecture ID 18906663)

uS17 family ribosomal protein such as human small ribosomal subunit protein uS17m, a component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins

CATH:  2.40.50.140
Gene Ontology:  GO:0015935|GO:0005840|GO:0019843|GO:0003735|GO:0006412
PubMed:  24524803|20534711|19616559|11909526
SCOP:  3000135

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_uS17 cd00364
Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins ...
 4-77 4.45e-27

Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins (S4, S17 and S20) that stabilize the entire 5' rRNA domain and increase the global stability of the rRNA structure. uS17 is highly conserved in all three major phylogenetic divisions. In eukaryotes, the S17 ortholog of the cytoplasmic ribosome is called S11 as are those of the mitochondrial and chloroplast ribosomes. uS17 plays a critical role in both subunit assembly and translational fidelity.


:

Pssm-ID: 466775  Cd Length: 73  Bit Score: 99.04  E-value: 4.45e-27
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254569000   4 QNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAEI 77
Cdd:cd00364    1 KILIGVVVSD-KMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDEPNECKVGDIVRIGECRPLSKTKRWVVVEI 73
 
Name Accession Description Interval E-value
Ribosomal_uS17 cd00364
Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins ...
 4-77 4.45e-27

Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins (S4, S17 and S20) that stabilize the entire 5' rRNA domain and increase the global stability of the rRNA structure. uS17 is highly conserved in all three major phylogenetic divisions. In eukaryotes, the S17 ortholog of the cytoplasmic ribosome is called S11 as are those of the mitochondrial and chloroplast ribosomes. uS17 plays a critical role in both subunit assembly and translational fidelity.


Pssm-ID: 466775  Cd Length: 73  Bit Score: 99.04  E-value: 4.45e-27
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254569000   4 QNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAEI 77
Cdd:cd00364    1 KILIGVVVSD-KMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDEPNECKVGDIVRIGECRPLSKTKRWVVVEI 73
Ribosomal_S17 pfam00366
Ribosomal protein S17;
8-76 2.29e-26

Ribosomal protein S17;


Pssm-ID: 459784  Cd Length: 68  Bit Score: 97.07  E-value: 2.29e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 254569000    8 GLVVSqGKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAE 76
Cdd:pfam00366   1 GVVVS-DKMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDENNECKVGDVVRIGECRPLSKTKRWVVVE 68
RpsQ COG0186
Ribosomal protein S17 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S17 ...
 1-79 5.73e-23

Ribosomal protein S17 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S17 is part of the Pathway/BioSystem: Ribosome 30S subunit


Pssm-ID: 439956  Cd Length: 87  Bit Score: 89.02  E-value: 5.73e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 254569000   1 MARQNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAEIKK 79
Cdd:COG0186    6 VRRKTLTGVVVSD-KMDKTVVVEVERRVKHPLYGKYVRRSKKYHAHDENNECKVGDTVRIMETRPLSKTKRWRVVEIVE 83
rpsQ PRK05610
30S ribosomal protein S17; Reviewed
 1-77 1.95e-20

30S ribosomal protein S17; Reviewed


Pssm-ID: 235532  Cd Length: 84  Bit Score: 82.12  E-value: 1.95e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 254569000   1 MARQNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAEI 77
Cdd:PRK05610   4 MPRKTLQGRVVSD-KMDKTIVVLVERRVKHPLYGKIVKRSKKYHAHDENNEAKIGDVVRIMETRPLSKTKRWRLVEI 79
uS17_bact TIGR03635
ribosomal protein uS17, bacterial form; This model describes the bacterial ribosomal small ...
 3-75 6.25e-19

ribosomal protein uS17, bacterial form; This model describes the bacterial ribosomal small subunit protein S17, while excluding cytosolic eukaryotic homologs and archaeal homologs. The model finds many, but not, chloroplast and mitochondrial counterparts to bacterial S17. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 274691  Cd Length: 72  Bit Score: 77.96  E-value: 6.25e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 254569000    3 RQNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVA 75
Cdd:TIGR03635   1 RKTLQGVVVSD-KMDKTVVVLVERRVKHPLYKKIVKRTKKYHAHDENNECKVGDVVRIIETRPLSKTKRWRLV 72
 
Name Accession Description Interval E-value
Ribosomal_uS17 cd00364
Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins ...
 4-77 4.45e-27

Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins (S4, S17 and S20) that stabilize the entire 5' rRNA domain and increase the global stability of the rRNA structure. uS17 is highly conserved in all three major phylogenetic divisions. In eukaryotes, the S17 ortholog of the cytoplasmic ribosome is called S11 as are those of the mitochondrial and chloroplast ribosomes. uS17 plays a critical role in both subunit assembly and translational fidelity.


Pssm-ID: 466775  Cd Length: 73  Bit Score: 99.04  E-value: 4.45e-27
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254569000   4 QNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAEI 77
Cdd:cd00364    1 KILIGVVVSD-KMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDEPNECKVGDIVRIGECRPLSKTKRWVVVEI 73
Ribosomal_S17 pfam00366
Ribosomal protein S17;
8-76 2.29e-26

Ribosomal protein S17;


Pssm-ID: 459784  Cd Length: 68  Bit Score: 97.07  E-value: 2.29e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 254569000    8 GLVVSqGKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAE 76
Cdd:pfam00366   1 GVVVS-DKMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDENNECKVGDVVRIGECRPLSKTKRWVVVE 68
RpsQ COG0186
Ribosomal protein S17 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S17 ...
 1-79 5.73e-23

Ribosomal protein S17 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S17 is part of the Pathway/BioSystem: Ribosome 30S subunit


Pssm-ID: 439956  Cd Length: 87  Bit Score: 89.02  E-value: 5.73e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 254569000   1 MARQNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAEIKK 79
Cdd:COG0186    6 VRRKTLTGVVVSD-KMDKTVVVEVERRVKHPLYGKYVRRSKKYHAHDENNECKVGDTVRIMETRPLSKTKRWRVVEIVE 83
rpsQ PRK05610
30S ribosomal protein S17; Reviewed
 1-77 1.95e-20

30S ribosomal protein S17; Reviewed


Pssm-ID: 235532  Cd Length: 84  Bit Score: 82.12  E-value: 1.95e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 254569000   1 MARQNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAEI 77
Cdd:PRK05610   4 MPRKTLQGRVVSD-KMDKTIVVLVERRVKHPLYGKIVKRSKKYHAHDENNEAKIGDVVRIMETRPLSKTKRWRLVEI 79
uS17_bact TIGR03635
ribosomal protein uS17, bacterial form; This model describes the bacterial ribosomal small ...
 3-75 6.25e-19

ribosomal protein uS17, bacterial form; This model describes the bacterial ribosomal small subunit protein S17, while excluding cytosolic eukaryotic homologs and archaeal homologs. The model finds many, but not, chloroplast and mitochondrial counterparts to bacterial S17. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 274691  Cd Length: 72  Bit Score: 77.96  E-value: 6.25e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 254569000    3 RQNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVA 75
Cdd:TIGR03635   1 RKTLQGVVVSD-KMDKTVVVLVERRVKHPLYKKIVKRTKKYHAHDENNECKVGDVVRIIETRPLSKTKRWRLV 72
rps17 CHL00142
ribosomal protein S17; Validated
 1-79 9.79e-15

ribosomal protein S17; Validated


Pssm-ID: 177064  Cd Length: 84  Bit Score: 67.38  E-value: 9.79e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 254569000   1 MARQNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNICKEGDIVRIEATRPLSSRKHFAVAEIKK 79
Cdd:CHL00142   1 MPVKEKIGIVVSN-KMNKTIVVAVENRYKHPIYGKIITKTKKYLVHDEENECNIGDQVLIEETRPLSKTKRWILKEILS 78
rps17p PRK08572
30S ribosomal protein S17P; Reviewed
 4-80 1.18e-08

30S ribosomal protein S17P; Reviewed


Pssm-ID: 236296 [Multi-domain]  Cd Length: 108  Bit Score: 51.45  E-value: 1.18e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 254569000   4 QNFIGLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHDEGNI-CKEGDIVRIEATRPLSSRKHFAVAEIKKN 80
Cdd:PRK08572  30 QVLEGTVVSD-KMHKTVVVEREYLHYVPKYERYEKRRSRIHAHNPPCIdAKVGDKVKIAECRPLSKTKSFVVVEKKER 106
PTZ00241 PTZ00241
40S ribosomal protein S11; Provisional
 8-88 1.24e-03

40S ribosomal protein S11; Provisional


Pssm-ID: 240326 [Multi-domain]  Cd Length: 158  Bit Score: 38.14  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254569000   8 GLVVSQgKMDKTVKVRVEQMAYNTKIHKSLFKRKNYLVHdeGNIC---KEGDIVRIEATRPLSSRKHFAVAEIKKNK--- 81
Cdd:PTZ00241  73 GVVIST-KMKRTIIIRRDYLHYVKKYNRYEKRHKNIPVH--CSPCfdvKEGDIVVVGQCRPLSKTVRFNVLKVEKNEiig 149


                 ....*....
gi 254569000  82 --GQQFAKY 88
Cdd:PTZ00241 150 nvRKQFVLF 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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