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Conserved domains on  [gi|528498010|ref|XP_005156887|]
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complex I intermediate-associated protein 30, mitochondrial isoform X1 [Danio rerio]

Protein Classification

CIA30 family protein( domain architecture ID 10554017)

CIA30 family protein similar to eukaryotic complex I intermediate-associated protein 30, a chaperone protein involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CIA30 pfam08547
Complex I intermediate-associated protein 30 (CIA30); This protein is associated with ...
 107-280 4.65e-63

Complex I intermediate-associated protein 30 (CIA30); This protein is associated with mitochondrial Complex I intermediate-associated protein 30 (CIA30) in human and mouse. The family is also present in Schizosaccharomyces pombe which does not contain the NADH dehydrogenase component of complex I, or many of the other essential subunits. This means it is possible that this family of protein may not be directly involved in oxidative phosphorylation.


:

Pssm-ID: 462515  Cd Length: 156  Bit Score: 196.27  E-value: 4.65e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528498010  107 WEFRGPESLNEWIVSSDQEIGGRSVAYVSLGKNNTtCLLYGTLSSTpprdgetRYSGYCSMRSKppkasfDRKKHYDWSS 186
Cdd:pfam08547   1 FDFTSPESLDKWRSVNDRVMGGVSTSSLKLSVDGT-ARFSGNLSLE-------NNGGFASVRSR------NFDPPLDLSG 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528498010  187 FNTLHLRIRGDGRPWMINVSAETyfsHQRDDIYSYFLYTRGGPyWQDVKIPFSKFFLSSRGRIQDSQHPLWLDKINTIGF 266
Cdd:pfam08547  67 YDGLELRVKGDGRTYKLNLRTES---LRDGDSYQADFYTTPGE-WQTVKIPFSDFVPTFRGRVVDDAPPLDLSKIKQIGL 142

                         170
                  ....*....|....
gi 528498010  267 TLGDKADGPFQLEI 280
Cdd:pfam08547 143 LLSDKQEGPFELEI 156
 
Name Accession Description Interval E-value
CIA30 pfam08547
Complex I intermediate-associated protein 30 (CIA30); This protein is associated with ...
 107-280 4.65e-63

Complex I intermediate-associated protein 30 (CIA30); This protein is associated with mitochondrial Complex I intermediate-associated protein 30 (CIA30) in human and mouse. The family is also present in Schizosaccharomyces pombe which does not contain the NADH dehydrogenase component of complex I, or many of the other essential subunits. This means it is possible that this family of protein may not be directly involved in oxidative phosphorylation.


Pssm-ID: 462515  Cd Length: 156  Bit Score: 196.27  E-value: 4.65e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528498010  107 WEFRGPESLNEWIVSSDQEIGGRSVAYVSLGKNNTtCLLYGTLSSTpprdgetRYSGYCSMRSKppkasfDRKKHYDWSS 186
Cdd:pfam08547   1 FDFTSPESLDKWRSVNDRVMGGVSTSSLKLSVDGT-ARFSGNLSLE-------NNGGFASVRSR------NFDPPLDLSG 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528498010  187 FNTLHLRIRGDGRPWMINVSAETyfsHQRDDIYSYFLYTRGGPyWQDVKIPFSKFFLSSRGRIQDSQHPLWLDKINTIGF 266
Cdd:pfam08547  67 YDGLELRVKGDGRTYKLNLRTES---LRDGDSYQADFYTTPGE-WQTVKIPFSDFVPTFRGRVVDDAPPLDLSKIKQIGL 142

                         170
                  ....*....|....
gi 528498010  267 TLGDKADGPFQLEI 280
Cdd:pfam08547 143 LLSDKQEGPFELEI 156
 
Name Accession Description Interval E-value
CIA30 pfam08547
Complex I intermediate-associated protein 30 (CIA30); This protein is associated with ...
 107-280 4.65e-63

Complex I intermediate-associated protein 30 (CIA30); This protein is associated with mitochondrial Complex I intermediate-associated protein 30 (CIA30) in human and mouse. The family is also present in Schizosaccharomyces pombe which does not contain the NADH dehydrogenase component of complex I, or many of the other essential subunits. This means it is possible that this family of protein may not be directly involved in oxidative phosphorylation.


Pssm-ID: 462515  Cd Length: 156  Bit Score: 196.27  E-value: 4.65e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528498010  107 WEFRGPESLNEWIVSSDQEIGGRSVAYVSLGKNNTtCLLYGTLSSTpprdgetRYSGYCSMRSKppkasfDRKKHYDWSS 186
Cdd:pfam08547   1 FDFTSPESLDKWRSVNDRVMGGVSTSSLKLSVDGT-ARFSGNLSLE-------NNGGFASVRSR------NFDPPLDLSG 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528498010  187 FNTLHLRIRGDGRPWMINVSAETyfsHQRDDIYSYFLYTRGGPyWQDVKIPFSKFFLSSRGRIQDSQHPLWLDKINTIGF 266
Cdd:pfam08547  67 YDGLELRVKGDGRTYKLNLRTES---LRDGDSYQADFYTTPGE-WQTVKIPFSDFVPTFRGRVVDDAPPLDLSKIKQIGL 142

                         170
                  ....*....|....
gi 528498010  267 TLGDKADGPFQLEI 280
Cdd:pfam08547 143 LLSDKQEGPFELEI 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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