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Conserved domains on  [gi|528517582|ref|XP_005162107|]
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sarcolemma associated protein b isoform X1 [Danio rerio]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 61-366 5.04e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 5.04e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  61 LLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAvfsmRQETHAAQEEVQVLRRTMEKTAAEREHEV--- 137
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELARLEQDIARLEerr 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 138 SALKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQAGELEKVQKDceslrrdcASLRSEREQLADK 217
Cdd:COG1196  312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA--------EAELAEAEEELEE 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 218 QQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNS 297
Cdd:COG1196  384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528517582 298 RIKELQKEYEEMQAELSGLRGkfENAEEEKRSVSLELQQSQERLRLMQDKDNHLSLLQPILAVAIGLVL 366
Cdd:COG1196  464 LLAELLEEAALLEAALAELLE--ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 61-366 5.04e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 5.04e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  61 LLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAvfsmRQETHAAQEEVQVLRRTMEKTAAEREHEV--- 137
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELARLEQDIARLEerr 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 138 SALKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQAGELEKVQKDceslrrdcASLRSEREQLADK 217
Cdd:COG1196  312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA--------EAELAEAEEELEE 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 218 QQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNS 297
Cdd:COG1196  384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528517582 298 RIKELQKEYEEMQAELSGLRGkfENAEEEKRSVSLELQQSQERLRLMQDKDNHLSLLQPILAVAIGLVL 366
Cdd:COG1196  464 LLAELLEEAALLEAALAELLE--ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 66-352 4.31e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 4.31e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    66 KRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVFSMR------QETHAAQEEVQVLRRTMEKTAAEREHEVSA 139
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIEELQKELYA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   140 LKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRA---TKQQAGELEKVQKDCESLRRDCASLRSEREQLAD 216
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELaeeLAELEEKLEELKEELESLEAELEELEAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   217 KQQKEKASLQNENSSLRSEkeqlqkkqqqlekeldssKKQNTSLSNTVKSLEKTQADLEKRLSVLQEE------------ 284
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQL------------------ELQIASLNNEIERLEARLERLEDRRERLQQEieellkkleeae 434

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528517582   285 HQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERLRLMQDKDNHLS 352
Cdd:TIGR02168  435 LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 57-355 5.74e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 5.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   57 ELQGLLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVFSMRQethAAQEEVQVLRRTMEKTAAEREHE 136
Cdd:pfam17380 273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQ---AEMDRQAAIYAEQERMAMERERE 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  137 VSALKGNLATLTSELEKWQQAANKYE--RELESVQASHLQQNQ-----------------QRDRATKQQAGELEKVQKDC 197
Cdd:pfam17380 350 LERIRQEERKRELERIRQEEIAMEISrmRELERLQMERQQKNErvrqeleaarkvkileeERQRKIQQQKVEMEQIRAEQ 429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  198 ESLR-RDCASLRSEREQLADKQQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDsskkqntslsntvkslEKTQADLEK 276
Cdd:pfam17380 430 EEARqREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKR----------------DRKRAEEQR 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  277 RLSVLQEEHQRDNGQLEQSNSRiKELQKEYEEMQAELSGLRGKFENAEEEKRSVSL-ELQQSQERLRLMQDKDNHLSLLQ 355
Cdd:pfam17380 494 RKILEKELEERKQAMIEEERKR-KLLEKEMEERQKAIYEEERRREAEEERRKQQEMeERRRIQEQMRKATEERSRLEAME 572
PRK12704 PRK12704
phosphodiesterase; Provisional
 61-223 2.85e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 39.76  E-value: 2.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  61 LLEEEKRANK--QQAEESAKQMKvlQTQLQKLQEEMENLRDQKDSAVFSMRQEthAAQEEVQVLRRtmEKTAAEREHEVS 138
Cdd:PRK12704  33 IKEAEEEAKRilEEAKKEAEAIK--KEALLEAKEEIHKLRNEFEKELRERRNE--LQKLEKRLLQK--EENLDRKLELLE 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 139 ALKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQAGE--LEKVQkdcESLRRDCASLRSEREQLAD 216
Cdd:PRK12704 107 KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAKEilLEKVE---EEARHEAAVLIKEIEEEAK 183


                 ....*..
gi 528517582 217 KQQKEKA 223
Cdd:PRK12704 184 EEADKKA 190
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 61-366 5.04e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 5.04e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  61 LLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAvfsmRQETHAAQEEVQVLRRTMEKTAAEREHEV--- 137
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELARLEQDIARLEerr 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 138 SALKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQAGELEKVQKDceslrrdcASLRSEREQLADK 217
Cdd:COG1196  312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA--------EAELAEAEEELEE 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 218 QQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNS 297
Cdd:COG1196  384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528517582 298 RIKELQKEYEEMQAELSGLRGkfENAEEEKRSVSLELQQSQERLRLMQDKDNHLSLLQPILAVAIGLVL 366
Cdd:COG1196  464 LLAELLEEAALLEAALAELLE--ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 66-352 4.31e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 4.31e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    66 KRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVFSMR------QETHAAQEEVQVLRRTMEKTAAEREHEVSA 139
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIEELQKELYA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   140 LKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRA---TKQQAGELEKVQKDCESLRRDCASLRSEREQLAD 216
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELaeeLAELEEKLEELKEELESLEAELEELEAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   217 KQQKEKASLQNENSSLRSEkeqlqkkqqqlekeldssKKQNTSLSNTVKSLEKTQADLEKRLSVLQEE------------ 284
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQL------------------ELQIASLNNEIERLEARLERLEDRRERLQQEieellkkleeae 434

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528517582   285 HQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERLRLMQDKDNHLS 352
Cdd:TIGR02168  435 LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 70-362 1.06e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  70 KQQAEEsAKQMKVLQTQLQKLQEEmenLRDQKDSAVFSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTS 149
Cdd:COG1196  206 ERQAEK-AERYRELKEELKELEAE---LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 150 ELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQA---GELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASLQ 226
Cdd:COG1196  282 ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEeleEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 227 NENSSLRSEKEQLQKKQQQLEKELD---SSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQ 303
Cdd:COG1196  362 EAEEALLEAEAELAEAEEELEELAEellEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 528517582 304 KEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERLRLMQDKDNHLSLLQPILAVAI 362
Cdd:COG1196  442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 64-341 2.03e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 2.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    64 EEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVFSMRQETHAAQEEVQVLRRTMEKTAAER---EHEVSAL 140
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIaqlSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   141 KGNLATLTSELEKWQQAANKYERELESVQAshlqqnqqrdratkqqagELEKVQKDCESLRRDCASLRSEREQLADKQQK 220
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEA------------------QIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   221 ekaslqnenssLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIK 300
Cdd:TIGR02168  822 -----------LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 528517582   301 ELQKEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERL 341
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 11-333 3.30e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 3.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    11 NKVSLIKDELSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVELqgllEEEKRANKQQAEESAKQMKVLQTQLQKL 90
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL----EQEIENVKSELKELEARIEELEEDLHKL 777

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    91 QEEMENLRDQKDSAVFsmrQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESVQA 170
Cdd:TIGR02169  778 EEALNDLEARLSHSRI---PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   171 ShLQQNQQRDRATKQQAGELEKVQKDCES----LRRDCASLRSEREQLADKQQKEKASLQNENSSLrSEKEQLQKKQQQL 246
Cdd:TIGR02169  855 E-IENLNGKKEELEEELEELEAALRDLESrlgdLKKERDELEAQLRELERKIEELEAQIEKKRKRL-SELKAKLEALEEE 932

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   247 EKELDSSKKQNTSLSNTVKSLEKTQADLEK---RLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGKFENA 323
Cdd:TIGR02169  933 LSEIEDPKGEDEEIPEEELSLEDVQAELQRveeEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012

                          330
                   ....*....|
gi 528517582   324 EEEKRSVSLE 333
Cdd:TIGR02169 1013 EKKKREVFME 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 61-342 7.28e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 7.28e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    61 LLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVFSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSAL 140
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   141 KGNLATLTSELEKWQQAANKYERELESVQASHlqqnQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQ- 219
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEI----EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAe 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   220 --KEKASLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNS 297
Cdd:TIGR02169  383 trDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAA 462

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 528517582   298 RIKELQKEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERLR 342
Cdd:TIGR02169  463 DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVR 507
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 98-347 1.11e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 1.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    98 RDQKDSAVFSMRQETHAAQEEVQVlrrtMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESVQAS---HLQ 174
Cdd:TIGR02168  665 SAKTNSSILERRREIEELEEKIEE----LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDlarLEA 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   175 QNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDSSk 254
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA- 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   255 kqnTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGKFENAEEEKRSVSLEL 334
Cdd:TIGR02168  820 ---ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL 896

                          250
                   ....*....|...
gi 528517582   335 QQSQERLRLMQDK 347
Cdd:TIGR02168  897 EELSEELRELESK 909
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3-347 4.99e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 4.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582     3 EQKLKDPINKVSLIKDELSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVELQGLLEEEKrankQQAEESAKQMKV 82
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE----AEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    83 LQTQLQKLQEEMENLRDQKDSAvFSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYE 162
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEA-EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   163 RELESVQashlQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLadkqQKEKASLQNENSSLRSEKEqlqkk 242
Cdd:TIGR02168  831 RRIAATE----RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELE----- 897

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   243 qqqlekeldsskkqntslsntvkSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGL-RGKFE 321
Cdd:TIGR02168  898 -----------------------ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEySLTLE 954

                          330       340
                   ....*....|....*....|....*.
gi 528517582   322 NAEEEKRSVSLELQQSQERLRLMQDK 347
Cdd:TIGR02168  955 EAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 63-341 1.13e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    63 EEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVfsMRQETHAAQEEVQVLRRTMEKTAAEREHEvsALKG 142
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE--RYQALLKEKREYEGYELLKEKEALERQKE--AIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   143 NLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQA----GELEKVQKDCESLRRDCASLRSEREQLADKQ 218
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlrvkEKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   219 QKEKA---SLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKT-------QADLEKRLSVLQEEHQRD 288
Cdd:TIGR02169  325 AKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEfaetrdeLKDYREKLEKLKREINEL 404

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 528517582   289 NGQLEQSNSRIKELQKEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERL 341
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL 457
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 86-361 1.58e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 1.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    86 QLQKLQEEMENLRDQKDSA---VFSMRQETHAAQEEVQVLRRTMEktaaEREHEVSALKGNLATLTSELEKWQQAANKYE 162
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLqseLRRIENRLDELSQELSDASRKIG----EIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   163 RELESVQAshlqqnqqrdratkqqagELEKVQKDCESLRRDCASLRSEREQLADKQQKEK-ASLQNENSSLRSEKEQLQK 241
Cdd:TIGR02169  751 QEIENVKS------------------ELKELEARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEA 812

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   242 KQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGKFE 321
Cdd:TIGR02169  813 RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD 892

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 528517582   322 NAEEEKRSVSLELQQSQERLrlmQDKDNHLSLLQPILAVA 361
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQI---EKKRKRLSELKAKLEAL 929
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 26-318 4.89e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 4.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    26 EASESEKVIQRLNQELQEANEQPNSSKYKCVELQGLLEEEkraNKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAV 105
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL---NKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKE 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   106 FSMrQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESVQASHlqqnqqrdRATKQ 185
Cdd:TIGR02169  315 REL-EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF--------AETRD 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   186 qagELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVK 265
Cdd:TIGR02169  386 ---ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAA 462

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528517582   266 SLEK----------TQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRG 318
Cdd:TIGR02169  463 DLSKyeqelydlkeEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHG 525
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 17-339 1.02e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    17 KDELSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVELQGLLEEEKRANKQQAEESAKqmkvLQTQLQKLQEEMEN 96
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR----LEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    97 LRDQKDSAvfSMRQETHAAQEEVQvlrrtmEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESVQASHLQQN 176
Cdd:TIGR02168  314 LERQLEEL--EAQLEELESKLDEL------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   177 QQRDRATKQQAgelekvqkdceSLRRDCASLRSEREQLADKQQKEKASLQNENSSLrsekeqlqkkqqqlekeldsSKKQ 256
Cdd:TIGR02168  386 SKVAQLELQIA-----------SLNNEIERLEARLERLEDRRERLQQEIEELLKKL--------------------EEAE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   257 NTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGKFENAEEEKRSVSLELQQ 336
Cdd:TIGR02168  435 LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN 514


                   ...
gi 528517582   337 SQE 339
Cdd:TIGR02168  515 QSG 517
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-251 1.18e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 1.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   2 EEQKLKDPINKVSLIKDELSRSTVEASESEKVIQRLNQELQEAN---EQPNSSKYKCVELQGLLEEEKRANKQQAEESAK 78
Cdd:COG1196  251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLaelARLEQDIARLEERRRELEERLEELEEELAELEE 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  79 QMKVLQTQLQKLQEEMENLRDQKDSAVFSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKwQQAA 158
Cdd:COG1196  331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL-EEAE 409

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 159 NKYERELESVQASHLQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASLQNENSSLRSEKEQ 238
Cdd:COG1196  410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489

                        250
                 ....*....|...
gi 528517582 239 LQKKQQQLEKELD 251
Cdd:COG1196  490 AARLLLLLEAEAD 502
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 68-277 1.96e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  68 ANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVfSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATL 147
Cdd:COG4942   17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALL-KQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 148 TSELEKWQQAANKYERELESVQ-----------------ASHLQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSE 210
Cdd:COG4942   96 RAELEAQKEELAELLRALYRLGrqpplalllspedfldaVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 528517582 211 REQLADKQQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKR 277
Cdd:COG4942  176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 21-308 4.83e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 4.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    21 SRSTVEASESEKViQRLNQELQEANEQPNSSKYKCVELQGLLEE---EKRANKQQAEESAKQMKVLQTQLQKLQEEMENL 97
Cdd:TIGR02169  664 GGILFSRSEPAEL-QRLRERLEGLKRELSSLQSELRRIENRLDElsqELSDASRKIGEIEKEIEQLEQEEEKLKERLEEL 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    98 RDQKDSavfsMRQETHAAQEEVQvlrrTMEKTAAEREHEVSALKGNLATLTSEL--EKWQQAANKYE--RELESVQASHL 173
Cdd:TIGR02169  743 EEDLSS----LEQEIENVKSELK----ELEARIEELEEDLHKLEEALNDLEARLshSRIPEIQAELSklEEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   174 QQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDSS 253
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDEL 894

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 528517582   254 KKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEE 308
Cdd:TIGR02169  895 EAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEE 949
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 26-233 1.04e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  26 EASESEKVIQRLNQELQEANEQPNSSKYKcvelQGLLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSav 105
Cdd:COG4942   21 AAAEAEAELEQLQQEIAELEKELAALKKE----EKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE-- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 106 fsMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQ 185
Cdd:COG4942   95 --LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 528517582 186 QAgELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASLQNENSSLR 233
Cdd:COG4942  173 RA-ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 3-217 1.35e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   3 EQKLKDPINKVSLIKDELSRSTVEASESEKVIQRLNQELQEANEQPNsskykcvELQGLLEEEKRANKQQAEESAKQMKV 82
Cdd:COG4942   40 EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-------ELEKEIAELRAELEAQKEELAELLRA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  83 LQTQLQklQEEMENLRDQKDSAVFSMRQETHAAQeeVQVLRRTMEKTAAEREhEVSALKGNLATLTSELEKWQQAANKYE 162
Cdd:COG4942  113 LYRLGR--QPPLALLLSPEDFLDAVRRLQYLKYL--APARREQAEELRADLA-ELAALRAELEAERAELEALLAELEEER 187

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 528517582 163 RELESVQASHLQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADK 217
Cdd:COG4942  188 AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 18-283 2.31e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    18 DELSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVELQGL---LEEEKRANKQQAEESAKQMKVLQTQLQKLQEEM 94
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    95 ENLRDQKDS--AVFSMRQETHAAQ----EEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESV 168
Cdd:TIGR02168  333 DELAEELAEleEKLEELKEELESLeaelEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   169 QASH-LQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASLqNENSSLRSEKEQLQKKQQQLE 247
Cdd:TIGR02168  413 EDRReRLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL-EEAEQALDAAERELAQLQARL 491

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 528517582   248 KELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQE 283
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSE 527
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
144-374 3.22e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 3.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 144 LATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLadKQQKEKA 223
Cdd:COG4717   44 RAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEEL--REELEKL 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 224 SLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQsnsRIKELQ 303
Cdd:COG4717  122 EKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEE---ELQDLA 198

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528517582 304 KEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERLRLMQDKDNHLSLLQPILAVAIGLVLALLYWCLG 374
Cdd:COG4717  199 EELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLL 269
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 5-336 3.49e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.70  E-value: 3.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    5 KLKDPINKVSLIKDELSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVELQGLLEEEKR---ANKQQAEESAKQMK 81
Cdd:TIGR04523 205 NLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKqlsEKQKELEQNNKKIK 284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   82 VLQTQLQKLQEEMENLRDQKDSAVFSMRQETHAAQEEVqvlRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKY 161
Cdd:TIGR04523 285 ELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKK---LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEK 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  162 ERELEsvqashlQQNQQRDRATKQQAGELEKVQKdCESLRRDCASLRSEREQLADKQQKEKASLQNENSSLRSEKEQLQK 241
Cdd:TIGR04523 362 QRELE-------EKQNEIEKLKKENQSYKQEIKN-LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKE 433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  242 KQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGKFE 321
Cdd:TIGR04523 434 TIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVK 513

                         330
                  ....*....|....*
gi 528517582  322 NAEEEKRSVSLELQQ 336
Cdd:TIGR04523 514 DLTKKISSLKEKIEK 528
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
83-319 3.88e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   83 LQTQLQKLQEEMENLRDqkdsavfsMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYE 162
Cdd:COG4913   223 TFEAADALVEHFDDLER--------AHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  163 RELESVQASHLQQNQQRDRATKQqageLEKVQKDCESLRRdcaslrsereQLADKQQKEKASLQNEnssLRSEKEQLQKK 242
Cdd:COG4913   295 AELEELRAELARLEAELERLEAR----LDALREELDELEA----------QIRGNGGDRLEQLERE---IERLERELEER 357

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 528517582  243 QQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGK 319
Cdd:COG4913   358 ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 57-355 5.74e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 5.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   57 ELQGLLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVFSMRQethAAQEEVQVLRRTMEKTAAEREHE 136
Cdd:pfam17380 273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQ---AEMDRQAAIYAEQERMAMERERE 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  137 VSALKGNLATLTSELEKWQQAANKYE--RELESVQASHLQQNQ-----------------QRDRATKQQAGELEKVQKDC 197
Cdd:pfam17380 350 LERIRQEERKRELERIRQEEIAMEISrmRELERLQMERQQKNErvrqeleaarkvkileeERQRKIQQQKVEMEQIRAEQ 429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  198 ESLR-RDCASLRSEREQLADKQQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDsskkqntslsntvkslEKTQADLEK 276
Cdd:pfam17380 430 EEARqREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKR----------------DRKRAEEQR 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  277 RLSVLQEEHQRDNGQLEQSNSRiKELQKEYEEMQAELSGLRGKFENAEEEKRSVSL-ELQQSQERLRLMQDKDNHLSLLQ 355
Cdd:pfam17380 494 RKILEKELEERKQAMIEEERKR-KLLEKEMEERQKAIYEEERRREAEEERRKQQEMeERRRIQEQMRKATEERSRLEAME 572
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
63-166 9.71e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.00  E-value: 9.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  63 EEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQ---KDSAVFSMRQETHAAQEEvqvlrrtmEKTAAEREHEVSA 139
Cdd:COG2433  398 EREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEleeKDERIERLERELSEARSE--------ERREIRKDREISR 469

                         90       100
                 ....*....|....*....|....*..
gi 528517582 140 LKGNLATLTSELEKWQQAANKYERELE 166
Cdd:COG2433  470 LDREIERLERELEEERERIEELKRKLE 496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 76-333 1.03e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 1.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  76 SAKQMKVLQTQLQKLQEEMENLRDQkdsavfsmRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQ 155
Cdd:COG4942   18 QADAAAEAEAELEQLQQEIAELEKE--------LAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 156 QAANKYERELESVQASHLQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRsereQLADKQQKEKASLQNEnsslrse 235
Cdd:COG4942   90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLK----YLAPARREQAEELRAD------- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 236 keqlqkkQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSG 315
Cdd:COG4942  159 -------LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                        250
                 ....*....|....*...
gi 528517582 316 LRGKFENAEEEKRSVSLE 333
Cdd:COG4942  232 LEAEAAAAAERTPAAGFA 249
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
72-299 1.08e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   72 QAEESAKQMKVLQTQLQKLQEEMENLRDQKD--SAVFSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALkgnlatLTS 149
Cdd:COG4913   222 DTFEAADALVEHFDDLERAHEALEDAREQIEllEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL------LEA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  150 ELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQAG----ELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASL 225
Cdd:COG4913   296 ELEELRAELARLEAELERLEARLDALREELDELEAQIRGnggdRLEQLEREIERLERELEERERRRARLEALLAALGLPL 375

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 528517582  226 QNENSSLRSEKEQLQKKQQQLEKELDSskkqntsLSNTVKSLEKTQADLEKRLSVLQEEHQRdngqLEQSNSRI 299
Cdd:COG4913   376 PASAEEFAALRAEAAALLEALEEELEA-------LEEALAEAEAALRDLRRELRELEAEIAS----LERRKSNI 438
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 11-326 2.17e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.00  E-value: 2.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   11 NKVSLIKDELSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVELQ---GLLEEEKRANKQQAEESAKQMKVLQTQL 87
Cdd:TIGR04523 342 EQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLEsqiNDLESKIQNQEKLNQQKDEQIKKLQQEK 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   88 QKLQEEMENLRDQKDSAvfsmRQETHAAQEEVQVLRRTMEKTAAEREH---EVSALKGNLATLTSELEKWQQAANKYERE 164
Cdd:TIGR04523 422 ELLEKEIERLKETIIKN----NSEIKDLTNQDSVKELIIKNLDNTRESletQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  165 LESVQASHLQQNQQRDRATKQQAGELEKVQK-DCESLRRDCASLRSEREQLADKQ-------QKEKASLQNENSSLRSEK 236
Cdd:TIGR04523 498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKlESEKKEKESKISDLEDELNKDDFelkkenlEKEIDEKNKEIEELKQTQ 577

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  237 EQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGL 316
Cdd:TIGR04523 578 KSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEI 657

                         330
                  ....*....|
gi 528517582  317 RGKFENAEEE 326
Cdd:TIGR04523 658 RNKWPEIIKK 667
PRK12704 PRK12704
phosphodiesterase; Provisional
 61-223 2.85e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 39.76  E-value: 2.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  61 LLEEEKRANK--QQAEESAKQMKvlQTQLQKLQEEMENLRDQKDSAVFSMRQEthAAQEEVQVLRRtmEKTAAEREHEVS 138
Cdd:PRK12704  33 IKEAEEEAKRilEEAKKEAEAIK--KEALLEAKEEIHKLRNEFEKELRERRNE--LQKLEKRLLQK--EENLDRKLELLE 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 139 ALKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQAGE--LEKVQkdcESLRRDCASLRSEREQLAD 216
Cdd:PRK12704 107 KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAKEilLEKVE---EEARHEAAVLIKEIEEEAK 183


                 ....*..
gi 528517582 217 KQQKEKA 223
Cdd:PRK12704 184 EEADKKA 190
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 20-343 3.79e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 39.39  E-value: 3.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    20 LSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVELQGLLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRD 99
Cdd:pfam01576  641 LARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV 720

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   100 QKDSAVFSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSelekwqqAANKYERELESVQASHLQQNQQR 179
Cdd:pfam01576  721 NMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVA-------AKKKLELDLKELEAQIDAANKGR 793

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   180 DRATKQqageLEKVQKDCESLRRDCASLRSEREQL---ADKQQKEKASLQNENSSLRSEKEQLQKKQQQLEKELDSSKKQ 256
Cdd:pfam01576  794 EEAVKQ----LKKLQAQMKDLQRELEEARASRDEIlaqSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADE 869

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   257 NTSLSNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKEYEEMQAELSGLRGKFENAEEEKRsvSLELQQ 336
Cdd:pfam01576  870 IASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQ--QLERQN 947


                   ....*..
gi 528517582   337 SQERLRL 343
Cdd:pfam01576  948 KELKAKL 954
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
272-347 3.86e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.51  E-value: 3.86e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528517582  272 ADLEKRLSVLQEEHQRdngqLEQSNSRIKELQKEYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERLRLMQDK 347
Cdd:COG4913   664 ASAEREIAELEAELER----LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR 735
PTZ00121 PTZ00121
MAEBL; Provisional
 18-333 4.49e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.35  E-value: 4.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   18 DELSRSTVEASESEKVIQRLNQ--ELQEANEQPNSSKYKCVELQGLLEEEKRANK-QQAEESAKQMKVLQTQLQKLQEEM 94
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKAEEakKADEAKKKAEEAKKKADEAKKAAEAKKKADEaKKAEEAKKADEAKKAEEAKKADEA 1539

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   95 ENLRDQKDSAVFSMRQETHAAQEEVQVL-------RRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELES 167
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKKAEEKKKAEeakkaeeDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  168 VQASHLQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQKEK----------------ASLQNENSS 231
Cdd:PTZ00121 1620 IKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKkkaeeakkaeedekkaAEALKKEAE 1699

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  232 LRSEKEQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQADLEKRlsvlQEEHQRDNGQLEQSNSRIKELQKEYEEMQA 311
Cdd:PTZ00121 1700 EAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK----AEEAKKDEEEKKKIAHLKKEEEKKAEEIRK 1775

                         330       340
                  ....*....|....*....|..
gi 528517582  312 ELSGLRGKFENAEEEKRSVSLE 333
Cdd:PTZ00121 1776 EKEAVIEEELDEEDEKRRMEVD 1797
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
8-203 4.59e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.13  E-value: 4.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    8 DPINKVSLIKDELSRSTVEASESEKVIQRLNQELQEANEQPNSSK------YKCVELQGLLEE--EKRANKQQAEESAKQ 79
Cdd:COG4913   607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeysWDEIDVASAEREiaELEAELERLDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   80 MKVLQTQLQKLQEEMENLRDQKDsavfsmrqethaaqeEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQ--QA 157
Cdd:COG4913   687 LAALEEQLEELEAELEELEEELD---------------ELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELraLL 751

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 528517582  158 ANKYERELESVQASHLQQNQQRDRatKQQAGELEKVQKDCESLRRD 203
Cdd:COG4913   752 EERFAAALGDAVERELRENLEERI--DALRARLNRAEEELERAMRA 795
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
73-325 5.46e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 38.87  E-value: 5.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  73 AEESAKQMKVLQTQLQKLQEEMENLRDQKDSAVFSMRQETHAAQ-----EEVQVLRRTMEKTAAEREHEVSALKGNLATL 147
Cdd:PRK02224 470 IEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERleerrEDLEELIAERRETIEEKRERAEELRERAAEL 549

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 148 TSELEKWQQAANKYERELESVQ--ASHLQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQKEKASL 225
Cdd:PRK02224 550 EAEAEEKREAAAEAEEEAEEAReeVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERL 629

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 226 QNENSSLRSEKEQLQkkqqqlekeldsskkqntslsntvkslektqadlEKRLSVLQEEHQRDNGQLEQSNSRIKELQKE 305
Cdd:PRK02224 630 AEKRERKRELEAEFD----------------------------------EARIEEAREDKERAEEYLEQVEEKLDELREE 675

                        250       260
                 ....*....|....*....|
gi 528517582 306 YEEMQAELSGLRGKFENAEE 325
Cdd:PRK02224 676 RDDLQAEIGAVENELEELEE 695
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
11-170 5.50e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 38.74  E-value: 5.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   11 NKVSLIKDELSRSTVEASESEKVIQRLNQELQEANEQPNSSKYKCVElqgLLEEEKRANKQQAEESAKQMKVLQTQLQKL 90
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLE---QLEREIERLERELEERERRRARLEALLAAL 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   91 QEEMENLRDqkdsAVFSMRQETHAAQEEVQVLRRTMEKTAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESVQA 170
Cdd:COG4913   372 GLPLPASAE----EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRD 447
mukB PRK04863
chromosome partition protein MukB;
34-342 5.59e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 38.78  E-value: 5.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582   34 IQRLNQELQEANEQPNSSKyKCVELQGLLEEEKRANKQQAEESAKQmkvLQTQLQKLQEEMEnlrdqkdsavfsmRQETH 113
Cdd:PRK04863  350 IERYQADLEELEERLEEQN-EVVEEADEQQEENEARAEAAEEEVDE---LKSQLADYQQALD-------------VQQTR 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  114 AAQ--EEVQVLRRTMEKTAAErEHEVSALKGNLATLTSELEKWQQAANKYERELESVQAsHLQQNQQRDRATKQQAGELE 191
Cdd:PRK04863  413 AIQyqQAVQALERAKQLCGLP-DLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQA-AHSQFEQAYQLVRKIAGEVS 490

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  192 KVQKDcESLRRDCASLRSEREQLADKQQkekasLQNENSSLRsekeQLQKKQQQLEKELDSSKKQNTSLSNTVKSLEKTQ 271
Cdd:PRK04863  491 RSEAW-DVARELLRRLREQRHLAEQLQQ-----LRMRLSELE----QRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQ 560

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  272 ADLEKRLSVLQEEhQRDNG--------QLEQSNSRIKELQK---EYEEMQAELSGLRGKFENAEEEKRSVSLELQQSQER 340
Cdd:PRK04863  561 EELEARLESLSES-VSEARerrmalrqQLEQLQARIQRLAArapAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLER 639


                  ..
gi 528517582  341 LR 342
Cdd:PRK04863  640 ER 641
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
64-234 7.03e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 38.60  E-value: 7.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  64 EEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKDSAvfsmrqETHAAQEEVQVLRRTMEKTAAEREHEVSALKGN 143
Cdd:COG4717   74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEEL------REELEKLEKLLQLLPLYQELEALEAELAELPER 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 144 LATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQAGELEKVQKDCESLRRDCASLRSEREQLADKQQKEKA 223
Cdd:COG4717  148 LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                        170
                 ....*....|.
gi 528517582 224 SLQNENSSLRS 234
Cdd:COG4717  228 ELEQLENELEA 238
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
86-341 7.65e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 38.48  E-value: 7.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  86 QLQKLQEEMENLRDQKdSAVFSMRQETHAAQEEVQvlRRTMEKTAAEREHEVSALKGNLATLTSELEKWQ---QAANKYE 162
Cdd:PRK02224 160 QLGKLEEYRERASDAR-LGVERVLSDQRGSLDQLK--AQIEEKEEKDLHERLNGLESELAELDEEIERYEeqrEQARETR 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 163 RELESVQASHLQQNQqrdratkqqagELEKVQKDCESLRRDCASLRSEREQLADK---QQKEKASLQNENSSLRSEKEQL 239
Cdd:PRK02224 237 DEADEVLEEHEERRE-----------ELETLEAEIEDLRETIAETEREREELAEEvrdLRERLEELEEERDDLLAEAGLD 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 240 QKKQQQLEKELDSSKKQNTSL--------------SNTVKSLEKTQADLEKRLSVLQEEHQRDNGQLEQSNSRIKELQKE 305
Cdd:PRK02224 306 DADAEAVEARREELEDRDEELrdrleecrvaaqahNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREE 385

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 528517582 306 YEEMQAELSGLRGKFENAEEEKRSVSLELQQSQERL 341
Cdd:PRK02224 386 IEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
34-225 7.73e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 38.21  E-value: 7.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582  34 IQRLNQELQEANEQpnsskykcvelqgllEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLRDQKdsAVFSMRQETH 113
Cdd:COG4717   73 LKELEEELKEAEEK---------------EEEYAELQEELEELEEELEELEAELEELREELEKLEKLL--QLLPLYQELE 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582 114 AAQEEVQVLRRTMEKtAAEREHEVSALKGNLATLTSELEKWQQAANKYERELESVQASHLQQNQQRDRATKQQA----GE 189
Cdd:COG4717  136 ALEAELAELPERLEE-LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLaeleEE 214

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 528517582 190 LEKVQKDCESLRRDCASLRSEREQLADKQQKEKASL 225
Cdd:COG4717  215 LEEAQEELEELEEELEQLENELEAAALEERLKEARL 250
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 19-223 8.10e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 38.51  E-value: 8.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    19 ELSRSTVEASESEkvIQRLNQELQEANEQPNSSKYKCVELQGLLEEEKRANKQQAEESAKQMKVLQTQLQKLQEEMENLR 98
Cdd:TIGR02169  304 ASLERSIAEKERE--LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528517582    99 DQKDsAVFSMRQETHAAQEEVQVLRRTMEKTA----------AEREHEVSALKGNLATLTSELEKWQQAANKYERELESV 168
Cdd:TIGR02169  382 ETRD-ELKDYREKLEKLKREINELKRELDRLQeelqrlseelADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 528517582   169 QAShLQQNQQRDRATKQqagELEKVQKDCESLRRDCASLRSEREQLADKQQKEKA 223
Cdd:TIGR02169  461 AAD-LSKYEQELYDLKE---EYDRVEKELSKLQRELAEAEAQARASEERVRGGRA 511
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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