NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|528509004|ref|XP_005173804|]
View 

MAP7 domain containing 1 isoform X2 [Danio rerio]

Protein Classification

MAP7 domain-containing protein( domain architecture ID 12064852)

MAP7 domain-containing protein such as MAP7D1 (microtubule-associated protein 7 domain containing 1) identified as a novel substrate of doublecortin-like kinase 1 (DCLK1)

Gene Ontology:  GO:0005737

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 502-646 1.38e-26

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


:

Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 106.28  E-value: 1.38e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  502 KPTAGTTDPEEAARVLAEKRRQAREQREKEEQERREQEQRSRALREEHLRREEEERRRRDEEAKLMAEQQRLQEE----- 576
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEerqrk 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528509004  577 --KEAQERARAEHEENLRLQKQREEAESKAKEEAEKQRIEREKHFQKEEQERLERKKRLEEIMKRTRKSDAG 646
Cdd:pfam05672  81 aeEEAEEREQREQEEQERLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKRTRKSDQA 152
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 370-510 6.52e-07

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 6.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  370 PNVKAKNRASSPATprsrPLSPNPavspkPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPP----- 444
Cdd:PHA03247 2722 PPGPAAARQASPAL----PAAPAP-----PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAvasls 2792

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528509004  445 KDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDP 510
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAP 2858
CCDC47 super family cl46382
PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of ...
 91-167 8.65e-05

PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of the PAT complex, an endoplasmic reticulum (ER)-resident membrane multiprotein complex that facilitates multi-pass membrane proteins insertion into membranes. The PAT complex, formed by CCDC47 and Asterix proteins, acts as an intramembrane chaperone by directly interacting with nascent transmembrane domains (TMDs), releasing its substrates upon correct folding, and is needed for optimal biogenesis of multi-pass membrane proteins. CCDC47 is required to maintain the stability of Asterix. CCDC47 is associated with various membrane-associated processes and is component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. It is also involved in the regulation of calcium ion homeostasis in the ER, being also required for proper protein degradation via the ERAD (ER-associated degradation) pathway.


The actual alignment was detected with superfamily member pfam07946:

Pssm-ID: 480722  Cd Length: 323  Bit Score: 45.25  E-value: 8.65e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 528509004   91 SSEQRQKqAKKRREERAKylAAKKAQwleKEEKARRLRESQLEERRRKleeqrlKTEKRRALLEEKQRQKLEKNKER 167
Cdd:pfam07946 255 RPEALKK-AKKTREEEIE--KIKKAA---EEERAEEAQEKKEEAKKKE------REEKLAKLSPEEQRKYEEKERKK 319
 
Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 502-646 1.38e-26

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 106.28  E-value: 1.38e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  502 KPTAGTTDPEEAARVLAEKRRQAREQREKEEQERREQEQRSRALREEHLRREEEERRRRDEEAKLMAEQQRLQEE----- 576
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEerqrk 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528509004  577 --KEAQERARAEHEENLRLQKQREEAESKAKEEAEKQRIEREKHFQKEEQERLERKKRLEEIMKRTRKSDAG 646
Cdd:pfam05672  81 aeEEAEEREQREQEEQERLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKRTRKSDQA 152
PHA03247 PHA03247
large tegument protein UL36; Provisional
 370-510 6.52e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 6.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  370 PNVKAKNRASSPATprsrPLSPNPavspkPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPP----- 444
Cdd:PHA03247 2722 PPGPAAARQASPAL----PAAPAP-----PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAvasls 2792

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528509004  445 KDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDP 510
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAP 2858
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 361-513 6.16e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 49.91  E-value: 6.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  361 VTRTKTEASPNVKAKNRASSPATPRSrplspnpavSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQ 440
Cdd:pfam05109 405 ITRTATNATTTTHKVIFSKAPESTTT---------SPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTS 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  441 PEP---------------PKDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSpePNTAISKPTA 505
Cdd:pfam05109 476 PTPagttsgaspvtpspsPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTS--PTSAVTTPTP 553


                  ....*...
gi 528509004  506 GTTDPEEA 513
Cdd:pfam05109 554 NATSPTPA 561
CCDC47 pfam07946
PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of ...
 91-167 8.65e-05

PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of the PAT complex, an endoplasmic reticulum (ER)-resident membrane multiprotein complex that facilitates multi-pass membrane proteins insertion into membranes. The PAT complex, formed by CCDC47 and Asterix proteins, acts as an intramembrane chaperone by directly interacting with nascent transmembrane domains (TMDs), releasing its substrates upon correct folding, and is needed for optimal biogenesis of multi-pass membrane proteins. CCDC47 is required to maintain the stability of Asterix. CCDC47 is associated with various membrane-associated processes and is component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. It is also involved in the regulation of calcium ion homeostasis in the ER, being also required for proper protein degradation via the ERAD (ER-associated degradation) pathway.


Pssm-ID: 462322  Cd Length: 323  Bit Score: 45.25  E-value: 8.65e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 528509004   91 SSEQRQKqAKKRREERAKylAAKKAQwleKEEKARRLRESQLEERRRKleeqrlKTEKRRALLEEKQRQKLEKNKER 167
Cdd:pfam07946 255 RPEALKK-AKKTREEEIE--KIKKAA---EEERAEEAQEKKEEAKKKE------REEKLAKLSPEEQRKYEEKERKK 319
PRK12704 PRK12704
phosphodiesterase; Provisional
 83-163 1.19e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 1.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  83 QTAKKDAVSsEQRQKQAKKRRE------ERAKYLAAKKAQWLEKEE----KARRL--RESQLEERRRKLEEQRLKTEKRR 150
Cdd:PRK12704  52 EAIKKEALL-EAKEEIHKLRNEfekelrERRNELQKLEKRLLQKEEnldrKLELLekREEELEKKEKELEQKQQELEKKE 130

                         90
                 ....*....|....*.
gi 528509004 151 ALLEE---KQRQKLEK 163
Cdd:PRK12704 131 EELEElieEQLQELER 146
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 89-187 2.46e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 2.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  89 AVSSEQRQKQAKKRREERAKYLAAKKAQwLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEKNKEry 168
Cdd:COG1196  293 LLAELARLEQDIARLEERRRELEERLEE-LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE-- 369

                         90
                 ....*....|....*....
gi 528509004 169 ESAIKRSTKKTWAEIRQQR 187
Cdd:COG1196  370 AEAELAEAEEELEELAEEL 388
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 378-524 6.66e-04

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 42.91  E-value: 6.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 378 ASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQT--PARVQAPAVAAVTVETKEPRQPEPPKDTKTAsivPD 455
Cdd:COG3266  252 GSALKAPSQASSASAPATTSLGEQQEVSLPPAVAAQPAAAAAaqPSAVALPAAPAAAAAAAAPAEAAAPQPTAAK---PV 328

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528509004 456 ITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEEAARVLAEKRRQA 524
Cdd:COG3266  329 VTETAAPAAPAPEAAAAAAAPAAPAVAKKLAADEQWLASQPASHYTLQLLGASSEAALEAFAAKHSLKG 397
GBP_C cd16269
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...
 75-187 1.87e-03

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.


Pssm-ID: 293879 [Multi-domain]  Cd Length: 291  Bit Score: 41.02  E-value: 1.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  75 STPGSSPNQTAKKDAVSSEQRQKQAKKRREERA--KYLAAKKAqwlekEEKARRLRESQLEERRRKLEEQRLKT---EKR 149
Cdd:cd16269  139 SVPGGYQLYLEDREKLVEKYRQVPRKGVKAEEVlqEFLQSKEA-----EAEAILQADQALTEKEKEIEAERAKAeaaEQE 213

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 528509004 150 RALLEEKQR---QKLEKNKERYESAIKRSTKKTWAEIRQQR 187
Cdd:cd16269  214 RKLLEEQQReleQKLEDQERSYEEHLRQLKEKMEEERENLL 254
 
Name Accession Description Interval E-value
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 502-646 1.38e-26

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 106.28  E-value: 1.38e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  502 KPTAGTTDPEEAARVLAEKRRQAREQREKEEQERREQEQRSRALREEHLRREEEERRRRDEEAKLMAEQQRLQEE----- 576
Cdd:pfam05672   1 KPSAGTTDAEEAARILAEKRRQAREQREREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEerqrk 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528509004  577 --KEAQERARAEHEENLRLQKQREEAESKAKEEAEKQRIEREKHFQKEEQERLERKKRLEEIMKRTRKSDAG 646
Cdd:pfam05672  81 aeEEAEEREQREQEEQERLQKQKEEAEAKAREEAERQRQEREKIMQQEEQERLERKKRIEEIMKRTRKSDQA 152
PHA03247 PHA03247
large tegument protein UL36; Provisional
 370-510 6.52e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 6.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  370 PNVKAKNRASSPATprsrPLSPNPavspkPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPP----- 444
Cdd:PHA03247 2722 PPGPAAARQASPAL----PAAPAP-----PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAvasls 2792

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528509004  445 KDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDP 510
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAP 2858
PHA03247 PHA03247
large tegument protein UL36; Provisional
 351-518 1.31e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 52.25  E-value: 1.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  351 KVEKKRQSQSVTRTKTEASPNVKAKNRASSPA----TPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAP 426
Cdd:PHA03247 2660 RVSRPRRARRLGRAAQASSPPQRPRRRAARPTvgslTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAP 2739

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  427 AVAAVTVETKEPRQPEPPKDTKTASIVPDITVSSAPATPLSPSAPitVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAG 506
Cdd:PHA03247 2740 APPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT--RPAVASLSESRESLPSPWDPADPPAAVLAPAAA 2817

                         170
                  ....*....|..
gi 528509004  507 TTDPEEAARVLA 518
Cdd:PHA03247 2818 LPPAASPAGPLP 2829
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 391-512 1.73e-06

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 51.27  E-value: 1.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 391 PNPAvsPKPSSSSGRTP-PGTKTRPKRAQTPARVQAPAVAAVtvetkepRQPEP-PKDTKTASIVPDITVS--SAPATPL 466
Cdd:PHA03269  40 PDPA--PAPHQAASRAPdPAVAPTSAASRKPDLAQAPTPAAS-------EKFDPaPAPHQAASRAPDPAVApqLAAAPKP 110

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 528509004 467 SPSAPITVAPQTPE--VVNAASTSSRSLSPEPNTAISKPTAGTTDPEE 512
Cdd:PHA03269 111 DAAEAFTSAAQAHEapADAGTSAASKKPDPAAHTQHSPPPFAYTRSME 158
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 350-521 1.95e-06

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 51.61  E-value: 1.95e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 350 EKVEKKRQSQSVTRTKTEASPNvkaknRASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVA 429
Cdd:PTZ00449 577 KKPEFPKDPKHPKDPEEPKKPK-----RPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGP 651

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 430 AVTVETKEPRQPEPPKDTKTASIVPDITVSSAPAT-------PLSPSAPITVAPQTPEVVNAASTSSRSLSPE------- 495
Cdd:PTZ00449 652 KIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSketkttvVLDESFESILKETLPETPGTPFTTPRPLPPKlprdeef 731

                        170       180
                 ....*....|....*....|....*.
gi 528509004 496 PNTAISKPTAGTTDPEEAARVLAEKR 521
Cdd:PTZ00449 732 PFEPIGDPDAEQPDDIEFFTPPEEER 757
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 361-513 6.16e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 49.91  E-value: 6.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  361 VTRTKTEASPNVKAKNRASSPATPRSrplspnpavSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQ 440
Cdd:pfam05109 405 ITRTATNATTTTHKVIFSKAPESTTT---------SPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTS 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  441 PEP---------------PKDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSpePNTAISKPTA 505
Cdd:pfam05109 476 PTPagttsgaspvtpspsPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTS--PTSAVTTPTP 553


                  ....*...
gi 528509004  506 GTTDPEEA 513
Cdd:pfam05109 554 NATSPTPA 561
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
368-516 1.03e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 49.08  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 368 ASPNVKAKNRASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKT---RPKRAQTPARVQAPAVAAVTVETKE--PRQPE 442
Cdd:PRK07003 381 PAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAppaAPAPPATADRGDDAADGDAPVPAKAnaRASAD 460

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 528509004 443 PPKDTKTASIVPDITVSSAPATPLSPSAPitVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEEAARV 516
Cdd:PRK07003 461 SRCDERDAQPPADSGSASAPASDAPPDAA--FEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEA 532
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 345-496 2.70e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 47.76  E-value: 2.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 345 SALSKEKVEKKRQSQSvtrtKTEASP-NVKAKNRASSPATPRSRPLSPNPAVSPKPSSssgrtpPGTKTRPKRAQTPARV 423
Cdd:PTZ00449 528 EGEEGEHEDSKESDEP----KEGGKPgETKEGEVGKKPGPAKEHKPSKIPTLSKKPEF------PKDPKHPKDPEEPKKP 597

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528509004 424 QAPAVAAVTVETKEPRQPEPPKDTKTASIVPDITvssAPATPLSPSAPitVAPQTPEVVNAASTSSRSLSPEP 496
Cdd:PTZ00449 598 KRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPK---SPKRPPPPQRP--SSPERPEGPKIIKSPKPPKSPKP 665
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
368-491 2.78e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 47.54  E-value: 2.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 368 ASPNVKAKNRASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPPKDT 447
Cdd:PRK07003 419 AATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAA 498

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 528509004 448 KTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRS 491
Cdd:PRK07003 499 PSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAP 542
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 360-476 5.07e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 46.63  E-value: 5.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 360 SVTRTKTEASPNVKAKNRASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPR 439
Cdd:PRK14951 376 AEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQA 455

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 528509004 440 QPEPPKDTKTASIVPDITVSSAPATPLSPSAPITVAP 476
Cdd:PRK14951 456 APETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
PHA03247 PHA03247
large tegument protein UL36; Provisional
 378-514 6.81e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 6.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  378 ASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPArvQAPAVAAVTVETKEPRQPEPPKDTKTASI----- 452
Cdd:PHA03247 2644 PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRA--ARPTVGSLTSLADPPPPPPTPEPAPHALVsatpl 2721

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528509004  453 --VPDITVSSAPATPLSPSAPI----TVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEEAA 514
Cdd:PHA03247 2722 ppGPAAARQASPALPAAPAPPAvpagPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
368-506 8.57e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 8.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 368 ASPNVKAKNRASSPATPrSRPLSPNPAVSPKPSSSSGRTPpgtKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPPKDT 447
Cdd:PRK07003 404 GAAGAALAPKAAAAAAA-TRAEAPPAAPAPPATADRGDDA---ADGDAPVPAKANARASADSRCDERDAQPPADSGSASA 479

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528509004 448 KTASIVPDITVSSAP---------ATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAG 506
Cdd:PRK07003 480 PASDAPPDAAFEPAPraaapsaatPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAG 547
CCDC47 pfam07946
PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of ...
 91-167 8.65e-05

PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of the PAT complex, an endoplasmic reticulum (ER)-resident membrane multiprotein complex that facilitates multi-pass membrane proteins insertion into membranes. The PAT complex, formed by CCDC47 and Asterix proteins, acts as an intramembrane chaperone by directly interacting with nascent transmembrane domains (TMDs), releasing its substrates upon correct folding, and is needed for optimal biogenesis of multi-pass membrane proteins. CCDC47 is required to maintain the stability of Asterix. CCDC47 is associated with various membrane-associated processes and is component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. It is also involved in the regulation of calcium ion homeostasis in the ER, being also required for proper protein degradation via the ERAD (ER-associated degradation) pathway.


Pssm-ID: 462322  Cd Length: 323  Bit Score: 45.25  E-value: 8.65e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 528509004   91 SSEQRQKqAKKRREERAKylAAKKAQwleKEEKARRLRESQLEERRRKleeqrlKTEKRRALLEEKQRQKLEKNKER 167
Cdd:pfam07946 255 RPEALKK-AKKTREEEIE--KIKKAA---EEERAEEAQEKKEEAKKKE------REEKLAKLSPEEQRKYEEKERKK 319
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 93-182 1.04e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.88  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRAllEEKQRQKLEKN-KERYESA 171
Cdd:pfam17380 431 EARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRA--EEQRRKILEKElEERKQAM 508

                          90
                  ....*....|.
gi 528509004  172 IKRSTKKTWAE 182
Cdd:pfam17380 509 IEEERKRKLLE 519
PRK12704 PRK12704
phosphodiesterase; Provisional
 83-163 1.19e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 1.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  83 QTAKKDAVSsEQRQKQAKKRRE------ERAKYLAAKKAQWLEKEE----KARRL--RESQLEERRRKLEEQRLKTEKRR 150
Cdd:PRK12704  52 EAIKKEALL-EAKEEIHKLRNEfekelrERRNELQKLEKRLLQKEEnldrKLELLekREEELEKKEKELEQKQQELEKKE 130

                         90
                 ....*....|....*.
gi 528509004 151 ALLEE---KQRQKLEK 163
Cdd:PRK12704 131 EELEElieEQLQELER 146
PHA03247 PHA03247
large tegument protein UL36; Provisional
 374-510 1.37e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 1.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  374 AKNRASSPATPRSRPLSPNPAVSPKPSSSSGR--TPPGTKTRPKRAQ----TPARVQAPAVAAVTVETKEPRQPEPPKDT 447
Cdd:PHA03247 2744 VPAGPATPGGPARPARPPTTAGPPAPAPPAAPaaGPPRRLTRPAVASlsesRESLPSPWDPADPPAAVLAPAAALPPAAS 2823

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528509004  448 KTASIVPdiTVSSAPATPLSPSAPitVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDP 510
Cdd:PHA03247 2824 PAGPLPP--PTSAQPTAPPPPPGP--PPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPP 2882
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 93-171 1.99e-04

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 44.41  E-value: 1.99e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528509004  93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEKNKERYESA 171
Cdd:PRK09510  67 QQQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAA 145
PTZ00121 PTZ00121
MAEBL; Provisional
 85-186 1.99e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 1.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   85 AKKDAVSSEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRAlLEEKQRQKLEKN 164
Cdd:PTZ00121 1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA-EELKKAEEKKKA 1566

                          90       100
                  ....*....|....*....|..
gi 528509004  165 KERYESAIKRSTKKTWAEIRQQ 186
Cdd:PTZ00121 1567 EEAKKAEEDKNMALRKAEEAKK 1588
PTZ00121 PTZ00121
MAEBL; Provisional
 92-182 2.10e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 2.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   92 SEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLE--------ERRRKLEEQRLKTEKRRAllEEKQRQKLEK 163
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYeeekkmkaEEAKKAEEAKIKAEELKK--AEEEKKKVEQ 1637

                          90
                  ....*....|....*....
gi 528509004  164 NKERYESAIKRSTKKTWAE 182
Cdd:PTZ00121 1638 LKKKEAEEKKKAEELKKAE 1656
PTZ00121 PTZ00121
MAEBL; Provisional
 43-182 2.17e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 2.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   43 EILKADDTTVTDSSLITDPPSKSEPIKSDPRPSTPGSSPNQTAKKDAVSSEQRQKQA--KKRREERAKYLAAKKAQWLEK 120
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAeeAKKAAEAAKAEAEAAADEAEA 1361

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528509004  121 EEKARRLRESQLEERRRKLEEQRLKTEKRRAllEEKQRQKLEKNKERYESAIKRSTKKTWAE 182
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKK--ADEAKKKAEEDKKKADELKKAAAAKKKAD 1421
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
361-544 2.39e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.48  E-value: 2.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 361 VTRTKTEASPNVKAKNRASSPATPRSRPlsPNPAVSPKPSSSSGRTPPGTK----TRPKRAQTPARVQAPAVAAVTVETK 436
Cdd:PRK12323 383 AQPAPAAAAPAAAAPAPAAPPAAPAAAP--AAAAAARAVAAAPARRSPAPEalaaARQASARGPGGAPAPAPAPAAAPAA 460

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 437 EPRQPEPPKDTKTASIVPditvSSAPATPLSPSAPITVAP----QTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEE 512
Cdd:PRK12323 461 AARPAAAGPRPVAAAAAA----APARAAPAAAPAPADDDPppweELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDD 536

                        170       180       190
                 ....*....|....*....|....*....|..
gi 528509004 513 AARVLAEKRRQAREQREKEEQERREQEQRSRA 544
Cdd:PRK12323 537 AFETLAPAPAAAPAPRAAAATEPVVAPRPPRA 568
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 365-499 2.39e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 44.71  E-value: 2.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 365 KTEASPNVKAKNRASSPAtprsRPLSPNPAVSPKPSSSSGRTPpgtkTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPP 444
Cdd:PRK14951 365 KPAAAAEAAAPAEKKTPA----RPEAAAPAAAPVAQAAAAPAP----AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAA 436

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 528509004 445 KDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTA 499
Cdd:PRK14951 437 APAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 89-187 2.46e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 2.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  89 AVSSEQRQKQAKKRREERAKYLAAKKAQwLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEKNKEry 168
Cdd:COG1196  293 LLAELARLEQDIARLEERRRELEERLEE-LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE-- 369

                         90
                 ....*....|....*....
gi 528509004 169 ESAIKRSTKKTWAEIRQQR 187
Cdd:COG1196  370 AEAELAEAEEELEELAEEL 388
PHA03247 PHA03247
large tegument protein UL36; Provisional
 368-516 2.71e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  368 ASPNVKAKNRASSPATPRSRPLSPNPAVSPKPSS-SSGRTPPGTKTRPKraqTPARVQAPAVAAVTVETKEPR------- 439
Cdd:PHA03247 2811 VLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGpPPPSLPLGGSVAPG---GDVRRRPPSRSPAAKPAAPARppvrrla 2887

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  440 QPEPPKDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRS---LSPEPNTA-ISKPTAGTTDPEEAAR 515
Cdd:PHA03247 2888 RPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPqppLAPTTDPAgAGEPSGAVPQPWLGAL 2967


                  .
gi 528509004  516 V 516
Cdd:PHA03247 2968 V 2968
PTZ00121 PTZ00121
MAEBL; Provisional
 83-182 3.86e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 3.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   83 QTAKKDAvSSEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRlKTEKRRALLEEKQRQKLE 162
Cdd:PTZ00121 1493 EEAKKKA-DEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK-KAEELKKAEEKKKAEEAK 1570

                          90       100
                  ....*....|....*....|
gi 528509004  163 KNKERYESAIKRSTKKTWAE 182
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAKKAE 1590
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 398-515 6.19e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.16  E-value: 6.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 398 KPSSSSGRTPPgtktRPKRAQTPARVQAPAVAAVTVETKEPRQPEPPKDTKTASIVPDITVSSAPATPLSPSAPITVAPQ 477
Cdd:PRK14951 365 KPAAAAEAAAP----AEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAA 440

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 528509004 478 TPEVVNAASTSSRSLSPEPnTAISKPTAGTTDPEEAAR 515
Cdd:PRK14951 441 APAAVALAPAPPAQAAPET-VAIPVRVAPEPAVASAAP 477
PTZ00121 PTZ00121
MAEBL; Provisional
 86-174 6.59e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 6.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   86 KKDAVSSEQRQKQAKKRREE-RAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRAlLEEKQRQKLEKN 164
Cdd:PTZ00121 1482 AKKADEAKKKAEEAKKKADEaKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKA-DELKKAEELKKA 1560

                          90
                  ....*....|
gi 528509004  165 KERYESAIKR 174
Cdd:PTZ00121 1561 EEKKKAEEAK 1570
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 378-524 6.66e-04

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 42.91  E-value: 6.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 378 ASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQT--PARVQAPAVAAVTVETKEPRQPEPPKDTKTAsivPD 455
Cdd:COG3266  252 GSALKAPSQASSASAPATTSLGEQQEVSLPPAVAAQPAAAAAaqPSAVALPAAPAAAAAAAAPAEAAAPQPTAAK---PV 328

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528509004 456 ITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEEAARVLAEKRRQA 524
Cdd:COG3266  329 VTETAAPAAPAPEAAAAAAAPAAPAVAKKLAADEQWLASQPASHYTLQLLGASSEAALEAFAAKHSLKG 397
PHA03247 PHA03247
large tegument protein UL36; Provisional
 378-517 6.81e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 6.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  378 ASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQA--------------PAVAAVTVETKEPRQPEP 443
Cdd:PHA03247 2628 PPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQassppqrprrraarPTVGSLTSLADPPPPPPT 2707

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 528509004  444 PKD--TKTASIVPdITVSSAPATPLSPSAPIT-VAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEEAARVL 517
Cdd:PHA03247 2708 PEPapHALVSATP-LPPGPAAARQASPALPAApAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRL 2783
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 393-510 6.87e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 6.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 393 PAVSPKPSSSSGRTPPGTktrPKRAQTPARVQAPAVAAVTVETKEPRQPEPPKDTKTASIVPDITVSSAPATPLSPSAPI 472
Cdd:PRK07764 390 GAGAPAAAAPSAAAAAPA---AAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 528509004 473 TVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDP 510
Cdd:PRK07764 467 APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPA 504
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 364-508 6.99e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 43.37  E-value: 6.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  364 TKTEASPNVKAKNRASSPATPRSRP------------LSPNPAVSPKPSSSSGRTPPGTKTRPKrAQTPARVQAPAVAAV 431
Cdd:pfam05109 470 TADVTSPTPAGTTSGASPVTPSPSPrdngteskapdmTSPTSAVTTPTPNATSPTPAVTTPTPN-ATSPTLGKTSPTSAV 548

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528509004  432 TVETKEPRQPEPPKDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAI--SKPTAGTT 508
Cdd:pfam05109 549 TTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVvtSPPKNATS 627
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 378-465 7.04e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 42.87  E-value: 7.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 378 ASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAqTPARVQAPAVAAVTVETKEPrqpePPKDTKTASIVPDIT 457
Cdd:PRK14950 368 PAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETA-TPPPVPPRPVAPPVPHTPES----APKLTRAAIPVDEKP 442


                 ....*...
gi 528509004 458 VSSAPATP 465
Cdd:PRK14950 443 KYTPPAPP 450
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 388-518 7.65e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 42.93  E-value: 7.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 388 PLSPNP------------AVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPPKDTKTASIVPD 455
Cdd:PRK07994 340 PLAPDRrmgvemtllrmlAFHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETT 419

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528509004 456 ITVSSA--------PATPLSPSAPitVAPQTPEVVNAASTSSRSLSPEPNTAISKPtagttDPEEAARVLA 518
Cdd:PRK07994 420 SQLLAArqqlqraqGATKAKKSEP--AAASRARPVNSALERLASVRPAPSALEKAP-----AKKEAYRWKA 483
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 349-509 8.21e-04

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 42.61  E-value: 8.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 349 KEKVEKKRQSQSVTRTKTEASPNVKAKNRASSPATPRSRPLSP-------NPAVSPKPSSSSGRTPPGTKTRPKRAQTPA 421
Cdd:PLN03209 331 KESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPLSPytayedlKPPTSPIPTPPSSSPASSKSVDAVAKPAEP 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 422 RVQAPAVAAVTVETKEPRQPEPPKD------TKTASIVPDITVSSAPATPLSPSAPIT-VAPQTPEVVNAASTSSRSLSP 494
Cdd:PLN03209 411 DVVPSPGSASNVPEVEPAQVEAKKTrplspyARYEDLKPPTSPSPTAPTGVSPSVSSTsSVPAVPDTAPATAATDAAAPP 490

                        170
                 ....*....|....*
gi 528509004 495 EPNTAISKPTAGTTD 509
Cdd:PLN03209 491 PANMRPLSPYAVYDD 505
PTZ00121 PTZ00121
MAEBL; Provisional
 93-185 8.86e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 8.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRAlleeKQRQKLEKNKERYESAI 172
Cdd:PTZ00121 1168 EARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKA----EAVKKAEEAKKDAEEAK 1243

                          90
                  ....*....|...
gi 528509004  173 KRSTKKTWAEIRQ 185
Cdd:PTZ00121 1244 KAEEERNNEEIRK 1256
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 358-505 8.94e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.64  E-value: 8.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  358 SQSVTRTKTEASPNVKAKNRASSPATPRSRPLS-PNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETK 436
Cdd:pfam17823 111 ASRALAAAASSSPSSAAQSLPAAIAALPSEAFSaPRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTA 190

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528509004  437 EPRQPEPPKDTKTASIVPDITVSSAPATPLSPSAPiTVAPQTPEVVNAASTSSRSLSPEPNTAISKPTA 505
Cdd:pfam17823 191 ASSAPTTAASSAPATLTPARGISTAATATGHPAAG-TALAAVGNSSPAAGTVTAAVGTVTPAALATLAA 258
PTZ00121 PTZ00121
MAEBL; Provisional
 90-171 1.22e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   90 VSSEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRAllEEKQRQKLEKNKERYE 169
Cdd:PTZ00121 1111 AEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKA--EDAKKAEAARKAEEVR 1188


                  ..
gi 528509004  170 SA 171
Cdd:PTZ00121 1189 KA 1190
PHA03247 PHA03247
large tegument protein UL36; Provisional
 378-510 1.23e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  378 ASSPATPRSRPLS--PNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPPkdtktASIVPd 455
Cdd:PHA03247 2872 AAKPAAPARPPVRrlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ-----PPLAP- 2945

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 528509004  456 iTVSSAPATPLSPSAPitvAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDP 510
Cdd:PHA03247 2946 -TTDPAGAGEPSGAVP---QPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPL 2996
PRK12704 PRK12704
phosphodiesterase; Provisional
 85-178 1.31e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  85 AKKDAvssEQRQKQAKKRREERAKylaAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQrQKLEKN 164
Cdd:PRK12704  36 AEEEA---KRILEEAKKEAEAIKK---EALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKL-ELLEKR 108

                         90
                 ....*....|....
gi 528509004 165 KERYESAIKRSTKK 178
Cdd:PRK12704 109 EEELEKKEKELEQK 122
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
378-516 1.37e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.14  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 378 ASSPATPRSRPlSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVqAPAVAAVTVETKEPRQPEPPKDTKTASIVPDIT 457
Cdd:PRK07003 371 GVPARVAGAVP-APGARAAAAVGASAVPAVTAVTGAAGAALAPKAA-AAAAATRAEAPPAAPAPPATADRGDDAADGDAP 448

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 528509004 458 VSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEEAARV 516
Cdd:PRK07003 449 VPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAV 507
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 83-187 1.43e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 1.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  83 QTAKKDAVSSEQRQKQAKKRREERAK----YLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQR 158
Cdd:COG1196  261 ELAELEAELEELRLELEELELELEEAqaeeYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340

                         90       100
                 ....*....|....*....|....*....
gi 528509004 159 QKLEKNKEryESAIKRSTKKTWAEIRQQR 187
Cdd:COG1196  341 ELEEELEE--AEEELEEAEAELAEAEEAL 367
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 358-478 1.63e-03

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 41.64  E-value: 1.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 358 SQSVTRTKTEASPNVKAKNRASSPATPRSRPLS--PNPAVSPKPSSSSGRTPPgtktrPKRAQTPARVQAPAVAAVTVET 435
Cdd:PHA03269  33 TSAATQKPDPAPAPHQAASRAPDPAVAPTSAASrkPDLAQAPTPAASEKFDPA-----PAPHQAASRAPDPAVAPQLAAA 107

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 528509004 436 KEPRQPEPPKDTKTASIVPDITVSSAPATPLSPSAPITVAPQT 478
Cdd:PHA03269 108 PKPDAAEAFTSAAQAHEAPADAGTSAASKKPDPAAHTQHSPPP 150
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 93-163 1.66e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 41.44  E-value: 1.66e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528509004   93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRlkteKRRALLEEKQRQKLEK 163
Cdd:pfam13868 275 EIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEA----ERRERIEEERQKKLKE 341
GBP_C cd16269
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...
 75-187 1.87e-03

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.


Pssm-ID: 293879 [Multi-domain]  Cd Length: 291  Bit Score: 41.02  E-value: 1.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  75 STPGSSPNQTAKKDAVSSEQRQKQAKKRREERA--KYLAAKKAqwlekEEKARRLRESQLEERRRKLEEQRLKT---EKR 149
Cdd:cd16269  139 SVPGGYQLYLEDREKLVEKYRQVPRKGVKAEEVlqEFLQSKEA-----EAEAILQADQALTEKEKEIEAERAKAeaaEQE 213

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 528509004 150 RALLEEKQR---QKLEKNKERYESAIKRSTKKTWAEIRQQR 187
Cdd:cd16269  214 RKLLEEQQReleQKLEDQERSYEEHLRQLKEKMEEERENLL 254
PHA03378 PHA03378
EBNA-3B; Provisional
 377-496 2.18e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 41.59  E-value: 2.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 377 RASSPATPRSRPLSPNPAVSPKpssssgrTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPPKDTKTASIVPDI 456
Cdd:PHA03378 687 IQWAPGTMQPPPRAPTPMRPPA-------APPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAA 759

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 528509004 457 TVSSAPATPLSPSAPitvAPQTPEVVNAASTSSRSLSPEP 496
Cdd:PHA03378 760 APGRARPPAAAPGAP---TPQPPPQAPPAPQQRPRGAPTP 796
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 368-511 2.92e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 2.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  368 ASPNVKAKNRASSPA-TPRSRPLSPNPAVS------PKPS-SSSGRTP--PGTKTRPKRAQTPARVQAPAVAAVTVETKE 437
Cdd:pfam05109 440 AAPNTTTGLPSSTHVpTNLTAPASTGPTVStadvtsPTPAgTTSGASPvtPSPSPRDNGTESKAPDMTSPTSAVTTPTPN 519

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  438 PRQPEP----PKDTKTASIVPDITVSSAPATPL----SPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTD 509
Cdd:pfam05109 520 ATSPTPavttPTPNATSPTLGKTSPTSAVTTPTpnatSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETS 599


                  ..
gi 528509004  510 PE 511
Cdd:pfam05109 600 PQ 601
ARGLU pfam15346
Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is ...
 93-163 3.62e-03

Arginine and glutamate-rich 1; ARGLU, arginine and glutamate-rich 1 protein family, is required for the oestrogen-dependent expression of ESR1 target genes. It functions in cooperation with MED1. The family of proteins is found in eukaryotes.


Pssm-ID: 405931 [Multi-domain]  Cd Length: 151  Bit Score: 38.49  E-value: 3.62e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528509004   93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLR---ESQLEERRRKLEE-QRLKTEKRRALLEEKQRQKLEK 163
Cdd:pfam15346  45 EARKIMEKQVLEELEREREAELEEERRKEEEERKKReelERILEENNRKIEEaQRKEAEERLAMLEEQRRMKEER 119
PHA03247 PHA03247
large tegument protein UL36; Provisional
 377-515 3.79e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 3.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  377 RASSPATPRSRPLSPNPAVSPK--------PSS----SSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRqPEPP 444
Cdd:PHA03247  332 GAMEVVSPLPRPRQHYPLGFPKrrrptwtpPSSledlSAGRHHPKRASLPTRKRRSARHAATPFARGPGGDDQTR-PAAP 410

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528509004  445 KDTKTASIVPDITVSSAPATPLSPsapitvaPQTPEvvnAASTSSRSLSPEPNTAISKPTAGTTDPEEAAR 515
Cdd:PHA03247  411 VPASVPTPAPTPVPASAPPPPATP-------LPSAE---PGSDDGPAPPPERQPPAPATEPAPDDPDDATR 471
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 389-519 3.98e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.56  E-value: 3.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 389 LSPNPAVSPKPSSSSGRTPpgtkTRPKRAQTPArvqAPAVAAVTVETKEPrQPEPPkdtktasivpditvssapatPLSP 468
Cdd:PRK14950 360 LVPVPAPQPAKPTAAAPSP----VRPTPAPSTR---PKAAAAANIPPKEP-VRETA--------------------TPPP 411

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 528509004 469 SAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAgttDPEEAARVLAE 519
Cdd:PRK14950 412 VPPRPVAPPVPHTPESAPKLTRAAIPVDEKPKYTPPA---PPKEEEKALIA 459
motB PRK12799
flagellar motor protein MotB; Reviewed
 345-479 4.12e-03

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 40.47  E-value: 4.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 345 SALSKEKVEKKRQSQSVTRTKTEASPNVKAKNRASSPatPRSRPLSPNPAVSPKPSSSSGRTP--------PGTKTRPKR 416
Cdd:PRK12799 280 RALDIEKATGLKQIDTHGTVPVAAVTPSSAVTQSSAI--TPSSAAIPSPAVIPSSVTTQSATTtqasavalSSAGVLPSD 357

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528509004 417 AQTPARVQAPAVAAVtvetKEPRQPEPPKDTKTASIVPDITVSSAPATPLsPSAPITVAPQTP 479
Cdd:PRK12799 358 VTLPGTVALPAAEPV----NMQPQPMSTTETQQSSTGNITSTANGPTTSL-PAAPASNIPVSP 415
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 83-187 4.34e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.69  E-value: 4.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  83 QTAKKDAVSSEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQ--LEERRRKLEEQRLKTEKRRALLEEKQRQK 160
Cdd:COG1196  298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELeeAEEELEEAEAELAEAEEALLEAEAELAEA 377

                         90       100
                 ....*....|....*....|....*..
gi 528509004 161 LEKNKERYESAIKRSTKKTWAEIRQQR 187
Cdd:COG1196  378 EEELEELAEELLEALRAAAELAAQLEE 404
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
97-173 4.34e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 40.43  E-value: 4.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  97 KQAKKRREERAKYLAAK-------KAQWLEKEEKARRLRE-----SQLEERRRKLEEQRLKTEKRRALLEEKQRQ--KLE 162
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTenieeliKEKEKELEEVLREINEisselPELREELEKLEKEVKELEELKEEIEELEKEleSLE 251

                         90
                 ....*....|.
gi 528509004 163 KNKERYESAIK 173
Cdd:PRK03918 252 GSKRKLEEKIR 262
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 93-167 4.45e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 39.90  E-value: 4.45e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528509004   93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEKNKER 167
Cdd:pfam13868 112 EEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKEREI 186
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 367-489 4.48e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 4.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 367 EASPNVKAKNRASSPATPRSRPLSPNPAVSPkpssSSGRTPPGTKTRPKRAQTPARVQAPA---VAAVTVETKEPRQPEP 443
Cdd:PRK07764 382 ERRLGVAGGAGAPAAAAPSAAAAAPAAAPAP----AAAAPAAAAAPAPAAAPQPAPAPAPApapPSPAGNAPAGGAPSPP 457

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 528509004 444 PKDTKTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSS 489
Cdd:PRK07764 458 PAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAP 503
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 367-514 4.80e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 4.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 367 EASPNVKAKNRASSPATPRSRPLS--PNPAVSPKPSSSSGRTPPGTKTRPkraQTPARVQAPAVAAVTVETKEPRQPEPP 444
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEeaARPAAPAAPAAPAAPAPAGAAAAP---AEASAAPAPGVAAPEHHPKHVAVPDAS 663

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528509004 445 KDT--KTASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEEAA 514
Cdd:PRK07764 664 DGGdgWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAA 735
PTZ00121 PTZ00121
MAEBL; Provisional
 86-186 5.25e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 5.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   86 KKDAVSSEQRQKQAKKRREERAKYLA--AKKAQWLEKEEKARRLResqLEERRRKLEEQRLKTEKRRalLEEKQRQKLEK 163
Cdd:PTZ00121 1687 EKKAAEALKKEAEEAKKAEELKKKEAeeKKKAEELKKAEEENKIK---AEEAKKEAEEDKKKAEEAK--KDEEEKKKIAH 1761

                          90       100
                  ....*....|....*....|...
gi 528509004  164 NKERYESAIKRSTKKTWAEIRQQ 186
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVIEEE 1784
Pinin_SDK_memA pfam04696
pinin/SDK/memA/ protein conserved region; Members of this family have very varied ...
 91-165 6.36e-03

pinin/SDK/memA/ protein conserved region; Members of this family have very varied localizations within the eukaryotic cell. pinin is known to localize at the desmosomes and is implicated in anchoring intermediate filaments to the desmosomal plaque. SDK2/3 is a dynamically localized nuclear protein thought to be involved in modulation of alternative pre-mRNA splicing. memA is a tumour marker preferentially expressed in human melanoma cell lines. A common feature of the members of this family is that they may all participate in regulating protein-protein interactions.


Pssm-ID: 461396 [Multi-domain]  Cd Length: 130  Bit Score: 37.66  E-value: 6.36e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528509004   91 SSEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKlEEQRLKTEKRRALLEEKQRQKLEKNK 165
Cdd:pfam04696  23 KEESKQKEKEERRAEIEKRLEEKAKQEKEELEERKREEREELFEERRA-EQIELRALEEKLELKELMETWHENLK 96
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 93-166 6.54e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 39.52  E-value: 6.54e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 528509004   93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEKNKE 166
Cdd:pfam13868  58 EEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREE 131
GBP_C cd16269
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...
 98-166 6.74e-03

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.


Pssm-ID: 293879 [Multi-domain]  Cd Length: 291  Bit Score: 39.10  E-value: 6.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  98 QAKKRREERAKYLAAKKAQWLEKEEKARRLRESQ------LEERRRKLEE--QRLK---TEKRRALLEEKQRQKLEKNKE 166
Cdd:cd16269  188 QADQALTEKEKEIEAERAKAEAAEQERKLLEEQQreleqkLEDQERSYEEhlRQLKekmEEERENLLKEQERALESKLKE 267
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 91-187 6.84e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 39.81  E-value: 6.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  91 SSEQRQKQAKKRREErakylaakkAQwlEKEEKARRLREsQLEERRRKLEEQRlktEKRRALLEEKQRQKLEKNKERYES 170
Cdd:PRK00409 524 SLEELERELEQKAEE---------AE--ALLKEAEKLKE-ELEEKKEKLQEEE---DKLLEEAEKEAQQAIKEAKKEADE 588

                         90
                 ....*....|....*..
gi 528509004 171 AIKRSTKKTWAEIRQQR 187
Cdd:PRK00409 589 IIKELRQLQKGGYASVK 605
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
370-513 6.87e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 6.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 370 PNVKAKNRASSPATPRSRPLSPNPAVSPKPSSSSgrtPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEP-PKDTK 448
Cdd:PRK12323 376 TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAA---PAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGaPAPAP 452

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528509004 449 TASIVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEEA 513
Cdd:PRK12323 453 APAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAA 517
PTZ00121 PTZ00121
MAEBL; Provisional
 85-173 6.88e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 6.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   85 AKKDAVSSEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEKN 164
Cdd:PTZ00121 1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597


                  ....*....
gi 528509004  165 KERYESAIK 173
Cdd:PTZ00121 1598 MKLYEEEKK 1606
PTZ00121 PTZ00121
MAEBL; Provisional
 85-182 7.18e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 7.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   85 AKKDAVSSEQRQKQAKKRREERAKYLAAKKAQWLEK--EEKARRLRESQLEERRRKLEEQRLKTEKRRAllEEKQRQKLE 162
Cdd:PTZ00121 1416 AKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKkaEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK--ADEAKKKAE 1493

                          90       100
                  ....*....|....*....|
gi 528509004  163 KNKERYESAIKRSTKKTWAE 182
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKAD 1513
PTZ00121 PTZ00121
MAEBL; Provisional
 64-187 7.62e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 7.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   64 KSEPIKSDPRPSTPGSSPNQTAKKDAVSSEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQR 143
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 528509004  144 lKTEKRRALLEEKQRQKLEKNKERYESAIKRSTKKTWAEIRQQR 187
Cdd:PTZ00121 1571 -KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK 1613
PRK03963 PRK03963
V-type ATP synthase subunit E; Provisional
 85-183 7.64e-03

V-type ATP synthase subunit E; Provisional


Pssm-ID: 167649 [Multi-domain]  Cd Length: 198  Bit Score: 38.58  E-value: 7.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  85 AKKDAvssEQRQKQAKKRREERAKYLAaKKAQWLEKEEKARRLRESQLEERRRKLeeqRLKTEKRRALLEEKQRQKLEKN 164
Cdd:PRK03963  26 AQKEA---EKIKEEARKRAESKAEWIL-RKAKTQAELEKQRIIANAKLEVRRKRL---AVQEELISEVLEAVRERLAELP 98

                         90
                 ....*....|....*....
gi 528509004 165 KERYESAIKRSTKKTWAEI 183
Cdd:PRK03963  99 EDEYFETLKALTKEAVEEL 117
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
83-166 8.07e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 39.47  E-value: 8.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  83 QTAKKDAvssEQRQKQAKKRREERAKYLAAKKAQWLEKEEK----------ARRLRESQLEERRRKLEEQRLKTEKRRAL 152
Cdd:COG2268  238 RIAEAEA---ELAKKKAEERREAETARAEAEAAYEIAEANAerevqrqleiAEREREIELQEKEAEREEAELEADVRKPA 314

                         90
                 ....*....|....
gi 528509004 153 LEEKQRQKLEKNKE 166
Cdd:COG2268  315 EAEKQAAEAEAEAE 328
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 97-174 8.21e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.53  E-value: 8.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  97 KQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQ---RQKLEKNKERYESAIK 173
Cdd:COG1196  216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELeelELELEEAQAEEYELLA 295


                 .
gi 528509004 174 R 174
Cdd:COG1196  296 E 296
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 358-512 8.27e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 39.69  E-value: 8.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 358 SQSVTRTKTEASPNVKAKNRASSPATPRSRPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKE 437
Cdd:PRK08691 368 ANAVIENTELQSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPPWEDAPDEAQTAA 447

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528509004 438 PRQPEPPKDTKTAS---IVPDITVSSAPATPLSPSAPITVAPQTPEVVNAASTSSRSLSPEPNTAISKPTAGTTDPEE 512
Cdd:PRK08691 448 GTAQTSAKSIQTASeaeTPPENQVSKNKAADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAEPFYGYGFPDN 525
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 83-178 8.28e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.53  E-value: 8.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  83 QTAKK-DAVSSEQRQKQAK---KRREERAKYLAAKKAQWLEKEEKARRLrESQLEERRRKLEEQRLKTEKRRALLEEKQ- 157
Cdd:COG1196  210 EKAERyRELKEELKELEAElllLKLRELEAELEELEAELEELEAELEEL-EAELAELEAELEELRLELEELELELEEAQa 288

                         90       100
                 ....*....|....*....|..
gi 528509004 158 -RQKLEKNKERYESAIKRSTKK 178
Cdd:COG1196  289 eEYELLAELARLEQDIARLEER 310
PTZ00121 PTZ00121
MAEBL; Provisional
 86-191 8.51e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 8.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   86 KKDAVSSEQRQKQAKKRREERAKylaaKKAQWLEKEEKARRLRE--SQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEK 163
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEElkKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742

                          90       100
                  ....*....|....*....|....*...
gi 528509004  164 NKERYESAIKRSTKKTWAEIRQQRWSWA 191
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 82-187 8.57e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.53  E-value: 8.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004  82 NQTAKKDAVSSEQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQRQKL 161
Cdd:COG1196  362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                         90       100
                 ....*....|....*....|....*.
gi 528509004 162 EKNKERYESAIKRSTKKTWAEIRQQR 187
Cdd:COG1196  442 EALEEAAEEEAELEEEEEALLELLAE 467
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 121-201 8.61e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 39.42  E-value: 8.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004 121 EEKARRLRE--SQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEKNKERYESAIKRSTKKTWAEIRQQRWSWAGGLNQTS 198
Cdd:PRK00409 526 EELERELEQkaEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASVK 605


                 ...
gi 528509004 199 RRE 201
Cdd:PRK00409 606 AHE 608
PRK12757 PRK12757
cell division protein FtsN; Provisional
 380-447 8.80e-03

cell division protein FtsN; Provisional


Pssm-ID: 237191 [Multi-domain]  Cd Length: 256  Bit Score: 38.87  E-value: 8.80e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528509004 380 SPATPRS----RPLSPNPAVSPKPSSSSGRTPPGTKTRPKRAQTPARVQAPAVAAVTVETKEPRQPEPPKDT 447
Cdd:PRK12757 111 TPQVPRStvqiQQQAQQQQPPATTAQPQPVTPPRQTTAPVQPQTPAPVRTQPAAPVTQAVEAPKVEAEKEKE 182
PTZ00121 PTZ00121
MAEBL; Provisional
 93-185 9.58e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 9.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRALLEEKQRQKLEKNKE------ 166
Cdd:PTZ00121 1186 EVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEarmahf 1265

                          90       100
                  ....*....|....*....|
gi 528509004  167 -RYESAIKRSTKKTWAEIRQ 185
Cdd:PTZ00121 1266 aRRQAAIKAEEARKADELKK 1285
PTZ00121 PTZ00121
MAEBL; Provisional
 93-185 9.74e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 9.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528509004   93 EQRQKQAKKRREERAKYLAAKKAQWLEKEEKARRLRESQLEERRRKLEEQRLKTEKRRAllEEKQRQKLEKNKE---RYE 169
Cdd:PTZ00121 1102 EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKA--EDARKAEEARKAEdakKAE 1179

                          90
                  ....*....|....*.
gi 528509004  170 SAIKRSTKKTWAEIRQ 185
Cdd:PTZ00121 1180 AARKAEEVRKAEELRK 1195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH