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Conserved domains on  [gi|530408427|ref|XP_005255484|]
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putative RNA-binding protein Luc7-like 1 isoform X2 [Homo sapiens]

Protein Classification

LUC7 domain-containing protein( domain architecture ID 12042729)

LUC7 domain-containing protein similar to Homo sapiens Luc7-like protein 3 that may play a role in RNA splicing

Gene Ontology:  GO:0003729|GO:0006376|GO:0005685

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LUC7 pfam03194
LUC7 N_terminus; This family contains the N terminal region of several LUC7 protein homologs ...
1-189 2.87e-72

LUC7 N_terminus; This family contains the N terminal region of several LUC7 protein homologs and only contains eukaryotic proteins. LUC7 has been shown to be a U1 snRNA associated protein with a role in splice site recognition. The family also contains human and mouse LUC7 like (LUC7L) proteins and human cisplatin resistance-associated overexpressed protein (CROP).


:

Pssm-ID: 460842 [Multi-domain]  Cd Length: 246  Bit Score: 223.63  E-value: 2.87e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427    1 MDLGECTKIHDLALRADYEIASKERD-LFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEE 79
Cdd:pfam03194  52 ADLGPCPKIHDEALKADYEKASKRKKkYGYEREFLRFLQKLIDDVDRKIRKGKQRLELTQEEIEQTDELKQEQISVLEEK 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427   80 IGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRN-SMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFG 158
Cdd:pfam03194 132 IKKLLEEAEELGEEGNVDEAQKLMKKVEELKEEKEELEQQYESlTKESAASQEKKMEVCEVCGAFLIVNDADRRLADHLT 211
                         170       180       190
                  ....*....|....*....|....*....|.
gi 530408427  159 GKLHLGFIQIREKLDQLRKTVAEKQEKRNQD 189
Cdd:pfam03194 212 GKQHLGYAKIRDTLEELKEKIEERREEREER 242
 
Name Accession Description Interval E-value
LUC7 pfam03194
LUC7 N_terminus; This family contains the N terminal region of several LUC7 protein homologs ...
1-189 2.87e-72

LUC7 N_terminus; This family contains the N terminal region of several LUC7 protein homologs and only contains eukaryotic proteins. LUC7 has been shown to be a U1 snRNA associated protein with a role in splice site recognition. The family also contains human and mouse LUC7 like (LUC7L) proteins and human cisplatin resistance-associated overexpressed protein (CROP).


Pssm-ID: 460842 [Multi-domain]  Cd Length: 246  Bit Score: 223.63  E-value: 2.87e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427    1 MDLGECTKIHDLALRADYEIASKERD-LFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEE 79
Cdd:pfam03194  52 ADLGPCPKIHDEALKADYEKASKRKKkYGYEREFLRFLQKLIDDVDRKIRKGKQRLELTQEEIEQTDELKQEQISVLEEK 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427   80 IGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRN-SMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFG 158
Cdd:pfam03194 132 IKKLLEEAEELGEEGNVDEAQKLMKKVEELKEEKEELEQQYESlTKESAASQEKKMEVCEVCGAFLIVNDADRRLADHLT 211
                         170       180       190
                  ....*....|....*....|....*....|.
gi 530408427  159 GKLHLGFIQIREKLDQLRKTVAEKQEKRNQD 189
Cdd:pfam03194 212 GKQHLGYAKIRDTLEELKEKIEERREEREER 242
LUC7 COG5200
U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and ...
1-177 1.61e-31

U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification];


Pssm-ID: 227527 [Multi-domain]  Cd Length: 258  Bit Score: 118.53  E-value: 1.61e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427   1 MDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEiSAEVSAKAEKVHELNEEI 80
Cdd:COG5200   52 RSLGKCPTSHEEKYKAEYERNGRERAEEYEWEYLRLLVRIVLSCNDGIRAAGLEDRTTPEE-FGKIKEKEELFNRVDESI 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427  81 GKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMP-ASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGG 159
Cdd:COG5200  131 GELGMEGDALAKRKLVERACSAFNELERLREERKEIKEAVYSMVEnNGQGTHQKLQVCGICGAYLSRLDTDRRLADHFNG 210
                        170
                 ....*....|....*...
gi 530408427 160 KLHLGFIQIREKLDQLRK 177
Cdd:COG5200  211 KLHLGYLLVRSDLADLLK 228
 
Name Accession Description Interval E-value
LUC7 pfam03194
LUC7 N_terminus; This family contains the N terminal region of several LUC7 protein homologs ...
1-189 2.87e-72

LUC7 N_terminus; This family contains the N terminal region of several LUC7 protein homologs and only contains eukaryotic proteins. LUC7 has been shown to be a U1 snRNA associated protein with a role in splice site recognition. The family also contains human and mouse LUC7 like (LUC7L) proteins and human cisplatin resistance-associated overexpressed protein (CROP).


Pssm-ID: 460842 [Multi-domain]  Cd Length: 246  Bit Score: 223.63  E-value: 2.87e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427    1 MDLGECTKIHDLALRADYEIASKERD-LFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEE 79
Cdd:pfam03194  52 ADLGPCPKIHDEALKADYEKASKRKKkYGYEREFLRFLQKLIDDVDRKIRKGKQRLELTQEEIEQTDELKQEQISVLEEK 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427   80 IGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRN-SMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFG 158
Cdd:pfam03194 132 IKKLLEEAEELGEEGNVDEAQKLMKKVEELKEEKEELEQQYESlTKESAASQEKKMEVCEVCGAFLIVNDADRRLADHLT 211
                         170       180       190
                  ....*....|....*....|....*....|.
gi 530408427  159 GKLHLGFIQIREKLDQLRKTVAEKQEKRNQD 189
Cdd:pfam03194 212 GKQHLGYAKIRDTLEELKEKIEERREEREER 242
LUC7 COG5200
U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and ...
1-177 1.61e-31

U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification];


Pssm-ID: 227527 [Multi-domain]  Cd Length: 258  Bit Score: 118.53  E-value: 1.61e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427   1 MDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEiSAEVSAKAEKVHELNEEI 80
Cdd:COG5200   52 RSLGKCPTSHEEKYKAEYERNGRERAEEYEWEYLRLLVRIVLSCNDGIRAAGLEDRTTPEE-FGKIKEKEELFNRVDESI 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530408427  81 GKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMP-ASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGG 159
Cdd:COG5200  131 GELGMEGDALAKRKLVERACSAFNELERLREERKEIKEAVYSMVEnNGQGTHQKLQVCGICGAYLSRLDTDRRLADHFNG 210
                        170
                 ....*....|....*...
gi 530408427 160 KLHLGFIQIREKLDQLRK 177
Cdd:COG5200  211 KLHLGYLLVRSDLADLLK 228
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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