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Conserved domains on  [gi|530418521|ref|XP_005260668|]
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zinc finger SWIM domain-containing protein 1 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF5909 super family cl44720
Domain of unknown function (DUF5909); This is the C-terminal region of the Zinc finger SWIM ...
 411-485 6.60e-35

Domain of unknown function (DUF5909); This is the C-terminal region of the Zinc finger SWIM domain-containing protein 1, whose function is currently unknown.


The actual alignment was detected with superfamily member pfam19286:

Pssm-ID: 466028  Cd Length: 84  Bit Score: 125.32  E-value: 6.60e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530418521  411 DMLPAQWTAGC---------ATSLDSILGSKWSETLDKHLAVTHLTEEVGQLLQHCTKEEFERRYSTLRELADSWIGPYE 481
Cdd:pfam19286   1 EMLPRQWQKGSdhlqpgenvADDLLEILKSDWDESLDKHLAVSDLTAEISRLLTQCSGEEFERRYSTLRELADSWIGPYE 80


                  ....
gi 530418521  482 QVQL 485
Cdd:pfam19286  81 QVKL 84
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 379-404 4.05e-05

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


:

Pssm-ID: 309540  Cd Length: 38  Bit Score: 40.48  E-value: 4.05e-05
                          10        20
                  ....*....|....*....|....*.
gi 530418521  379 PASCSCYFNQAFHLPCRHILAMLSAR 404
Cdd:pfam04434  12 KASCSCPDFQLNGIPCKHALAVLLAL 37
 
Name Accession Description Interval E-value
DUF5909 pfam19286
Domain of unknown function (DUF5909); This is the C-terminal region of the Zinc finger SWIM ...
 411-485 6.60e-35

Domain of unknown function (DUF5909); This is the C-terminal region of the Zinc finger SWIM domain-containing protein 1, whose function is currently unknown.


Pssm-ID: 466028  Cd Length: 84  Bit Score: 125.32  E-value: 6.60e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530418521  411 DMLPAQWTAGC---------ATSLDSILGSKWSETLDKHLAVTHLTEEVGQLLQHCTKEEFERRYSTLRELADSWIGPYE 481
Cdd:pfam19286   1 EMLPRQWQKGSdhlqpgenvADDLLEILKSDWDESLDKHLAVSDLTAEISRLLTQCSGEEFERRYSTLRELADSWIGPYE 80


                  ....
gi 530418521  482 QVQL 485
Cdd:pfam19286  81 QVKL 84
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 379-404 4.05e-05

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


Pssm-ID: 309540  Cd Length: 38  Bit Score: 40.48  E-value: 4.05e-05
                          10        20
                  ....*....|....*....|....*.
gi 530418521  379 PASCSCYFNQAFHLPCRHILAMLSAR 404
Cdd:pfam04434  12 KASCSCPDFQLNGIPCKHALAVLLAL 37
 
Name Accession Description Interval E-value
DUF5909 pfam19286
Domain of unknown function (DUF5909); This is the C-terminal region of the Zinc finger SWIM ...
 411-485 6.60e-35

Domain of unknown function (DUF5909); This is the C-terminal region of the Zinc finger SWIM domain-containing protein 1, whose function is currently unknown.


Pssm-ID: 466028  Cd Length: 84  Bit Score: 125.32  E-value: 6.60e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530418521  411 DMLPAQWTAGC---------ATSLDSILGSKWSETLDKHLAVTHLTEEVGQLLQHCTKEEFERRYSTLRELADSWIGPYE 481
Cdd:pfam19286   1 EMLPRQWQKGSdhlqpgenvADDLLEILKSDWDESLDKHLAVSDLTAEISRLLTQCSGEEFERRYSTLRELADSWIGPYE 80


                  ....
gi 530418521  482 QVQL 485
Cdd:pfam19286  81 QVKL 84
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 379-404 4.05e-05

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


Pssm-ID: 309540  Cd Length: 38  Bit Score: 40.48  E-value: 4.05e-05
                          10        20
                  ....*....|....*....|....*.
gi 530418521  379 PASCSCYFNQAFHLPCRHILAMLSAR 404
Cdd:pfam04434  12 KASCSCPDFQLNGIPCKHALAVLLAL 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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