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Conserved domains on  [gi|530402420|ref|XP_005266473|]
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lambda-crystallin homolog isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06129 super family cl35428
3-hydroxyacyl-CoA dehydrogenase; Validated
 9-215 7.93e-80

3-hydroxyacyl-CoA dehydrogenase; Validated


The actual alignment was detected with superfamily member PRK06129:

Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 241.10  E-value: 7.93e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPNIQEAVEGA 88
Cdd:PRK06129   5 VAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTT 168
Cdd:PRK06129  84 DYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVPAPWTAPAT 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 530402420 169 VDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVE--LASV 215
Cdd:PRK06129 164 LARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVAdgVASV 212
 
Name Accession Description Interval E-value
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
 9-215 7.93e-80

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 241.10  E-value: 7.93e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPNIQEAVEGA 88
Cdd:PRK06129   5 VAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTT 168
Cdd:PRK06129  84 DYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVPAPWTAPAT 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 530402420 169 VDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVE--LASV 215
Cdd:PRK06129 164 LARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVAdgVASV 212
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
 9-211 1.33e-68

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 211.51  E-value: 1.33e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPNIqEAVEGA 88
Cdd:COG1250    5 VAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEE-EADAALARITPTTDL-AALADA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTT 168
Cdd:COG1250   83 DLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATSDET 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 530402420 169 VDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVE 211
Cdd:COG1250  163 VATAVAFARRLGKTPVVV-KDTPGFIVNRILVPYLNEAIRLLE 204
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
 9-186 2.01e-63

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 194.68  E-value: 2.01e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420    9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPNIQEAVeGA 88
Cdd:pfam02737   2 VAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRITEE-EVDAALARISFTTDLAAAV-DA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTT 168
Cdd:pfam02737  80 DLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPET 159

                         170
                  ....*....|....*...
gi 530402420  169 VDRTHALMKKIGQCPMRV 186
Cdd:pfam02737 160 VATTVELAKKIGKTPVVV 177
 
Name Accession Description Interval E-value
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
 9-215 7.93e-80

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 241.10  E-value: 7.93e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPNIQEAVEGA 88
Cdd:PRK06129   5 VAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTT 168
Cdd:PRK06129  84 DYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVPAPWTAPAT 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 530402420 169 VDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVE--LASV 215
Cdd:PRK06129 164 LARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVAdgVASV 212
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
 9-211 1.33e-68

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 211.51  E-value: 1.33e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPNIqEAVEGA 88
Cdd:COG1250    5 VAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEE-EADAALARITPTTDL-AALADA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTT 168
Cdd:COG1250   83 DLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATSDET 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 530402420 169 VDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVE 211
Cdd:COG1250  163 VATAVAFARRLGKTPVVV-KDTPGFIVNRILVPYLNEAIRLLE 204
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
 9-186 2.01e-63

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 194.68  E-value: 2.01e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420    9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPNIQEAVeGA 88
Cdd:pfam02737   2 VAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRITEE-EVDAALARISFTTDLAAAV-DA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTT 168
Cdd:pfam02737  80 DLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPET 159

                         170
                  ....*....|....*...
gi 530402420  169 VDRTHALMKKIGQCPMRV 186
Cdd:pfam02737 160 VATTVELAKKIGKTPVVV 177
PRK07531 PRK07531
carnitine 3-dehydrogenase;
11-210 1.09e-46

carnitine 3-dehydrogenase;


Pssm-ID: 236044 [Multi-domain]  Cd Length: 495  Bit Score: 160.67  E-value: 1.09e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  11 IVGSGVIGRSWAMLFASGGFQVKLYDIE---QQQIRNALENIRKEMKLLEQAgslkgSLSVEEQLSLisgCPNIQEAVEG 87
Cdd:PRK07531   9 CIGGGVIGGGWAARFLLAGIDVAVFDPHpeaERIIGEVLANAERAYAMLTDA-----PLPPEGRLTF---CASLAEAVAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  88 AMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPT 167
Cdd:PRK07531  81 ADWIQESVPERLDLKRRVLAEIDAAARPDALIGSSTSGFLPSDLQEGMTHPERLFVAHPYNPVYLLPLVELVGGGKTSPE 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 530402420 168 TVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLV 210
Cdd:PRK07531 161 TIRRAKEILREIGMKPVHIAKEIDAFVGDRLLEALWREALWLV 203
PRK06130 PRK06130
3-hydroxybutyryl-CoA dehydrogenase; Validated
 11-211 1.28e-45

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 235707 [Multi-domain]  Cd Length: 311  Bit Score: 153.39  E-value: 1.28e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  11 IVGSGVIGRSWAMLFASGGFQVKLYDIEQqqirNALENIRKemKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGAMH 90
Cdd:PRK06130   9 IIGAGTMGSGIAALFARKGLQVVLIDVME----GALERARG--VIERALGVYAPLGIASAGMGRIRMEAGLAAAVSGADL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  91 IQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVD 170
Cdd:PRK06130  83 VIEAVPEKLELKRDVFARLDGLCDPDTIFATNTSGLPITAIAQAVTRPERFVGTHFFTPADVIPLVEVVRGDKTSPQTVA 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 530402420 171 RTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVE 211
Cdd:PRK06130 163 TTMALLRSIGKRPVLVKKDIPGFIANRIQHALAREAISLLE 203
PRK07066 PRK07066
L-carnitine dehydrogenase;
12-210 9.84e-37

L-carnitine dehydrogenase;


Pssm-ID: 168796 [Multi-domain]  Cd Length: 321  Bit Score: 130.73  E-value: 9.84e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  12 VGSGVIGRSWAMLFASGGFQVKLYDIE---QQQIRNALENirkEMKLLEQAGSLKGSlsVEEQLSLIsgcPNIQEAVEGA 88
Cdd:PRK07066  13 IGSGVIGSGWVARALAHGLDVVAWDPApgaEAALRANVAN---AWPALERQGLAPGA--SPARLRFV---ATIEACVADA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTT 168
Cdd:PRK07066  85 DFIQESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARATHPERCVVGHPFNPVYLLPLVEVLGGERTAPEA 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 530402420 169 VDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLV 210
Cdd:PRK07066 165 VDAAMGIYRALGMRPLHVRKEVPGFIADRLLEALWREALHLV 206
PRK08293 PRK08293
3-hydroxyacyl-CoA dehydrogenase;
9-198 4.08e-32

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 181359 [Multi-domain]  Cd Length: 287  Bit Score: 117.73  E-value: 4.08e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGA 88
Cdd:PRK08293   6 VTVAGAGVLGSQIAFQTAFHGFDVTIYDISDEALEKAKERIAKLADRYVRDLEATKEAPAEAALNRITLTTDLAEAVKDA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  89 MHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKL---------FAGLvhvkqcivaHPVNPPYYIPLVELV 159
Cdd:PRK08293  86 DLVIEAVPEDPEIKGDFYEELAKVAPEKTIFATNSSTLLPSQFaeatgrpekFLAL---------HFANEIWKNNTAEIM 156

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 530402420 160 PHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRL 198
Cdd:PRK08293 157 GHPGTDPEVFDTVVAFAKAIGMVPIVLKKEQPGYILNSL 195
PRK09260 PRK09260
3-hydroxyacyl-CoA dehydrogenase;
9-211 2.00e-30

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 236434 [Multi-domain]  Cd Length: 288  Bit Score: 113.35  E-value: 2.00e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQirnaLENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCP---NIQEAV 85
Cdd:PRK09260   4 LVVVGAGVMGRGIAYVFAVSGFQTTLVDIKQEQ----LESAQQEIASIFEQGVARGKLTEAARQAALARLSyslDLKAAV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  86 EGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETA 165
Cdd:PRK09260  80 ADADLVIEAVPEKLELKKAVFETADAHAPAECYIATNTSTMSPTEIASFTKRPERVIAMHFFNPVHKMKLVELIRGLETS 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 530402420 166 PTTVDRTHALMKKIGQCPMRVQkEVAGFVLNRLQYAIISEA-WRLVE 211
Cdd:PRK09260 160 DETVQVAKEVAEQMGKETVVVN-EFPGFVTSRISALVGNEAfYMLQE 205
PRK05808 PRK05808
3-hydroxybutyryl-CoA dehydrogenase; Validated
 9-206 4.19e-29

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 180269 [Multi-domain]  Cd Length: 282  Bit Score: 109.67  E-value: 4.19e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQagslKGSLSVEEQ---LSLISGCPNIQEAV 85
Cdd:PRK05808   6 IGVIGAGTMGNGIAQVCAVAGYDVVMVDISDAAVDRGLATITKSLDRLVK----KGKMTEADKeaaLARITGTTDLDDLK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  86 EGAMHIqECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETA 165
Cdd:PRK05808  82 DADLVI-EAATENMDLKKKIFAQLDEIAKPEAILATNTSSLSITELAAATKRPDKVIGMHFFNPVPVMKLVEIIRGLATS 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 530402420 166 PTTVDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEA 206
Cdd:PRK05808 161 DATHEAVEALAKKIGKTPVEV-KNAPGFVVNRILIPMINEA 200
PRK08269 PRK08269
3-hydroxybutyryl-CoA dehydrogenase; Validated
 17-211 5.53e-27

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181340 [Multi-domain]  Cd Length: 314  Bit Score: 104.75  E-value: 5.53e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  17 IGRSWAMLFASGGFQVKLYDIEQQQI-------RNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPNIQ--EAVEG 87
Cdd:PRK08269   1 MGQGIALAFAFAGHDVTLIDFKPRDAagwraldAEARAEIERTLAALVALGRIDAA-QADAVLARIAVVARDGaaDALAD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  88 AMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPT 167
Cdd:PRK08269  80 ADLVFEAVPEVLDAKREALRWLGRHVDADAIIASTTSTFLVTDLQRHVAHPERFLNAHWLNPAYLMPLVEVSPSDATDPA 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 530402420 168 TVDRTHALMKKIGQCPMrVQKEVAGFVLNRLQYAIISEAWRLVE 211
Cdd:PRK08269 160 VVDRLAALLERIGKVPV-VCGPSPGYIVPRIQALAMNEAARMVE 202
PRK06035 PRK06035
3-hydroxyacyl-CoA dehydrogenase; Validated
 11-211 1.09e-26

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 180361 [Multi-domain]  Cd Length: 291  Bit Score: 103.42  E-value: 1.09e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  11 IVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKE----MKLLEqagslKGSLSVEEQLSLIS--GCPNIQEA 84
Cdd:PRK06035   8 VVGSGVMGQGIAQVFARTGYDVTIVDVSEEILKNAMELIESGpyglRNLVE-----KGKMSEDEAKAIMAriRTSTSYES 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  85 VEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPET 164
Cdd:PRK06035  83 LSDADFIVEAVPEKLDLKRKVFAELERNVSPETIIASNTSGIMIAEIATALERKDRFIGMHWFNPAPVMKLIEVVRAALT 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 530402420 165 APTTVDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVE 211
Cdd:PRK06035 163 SEETFNTTVELSKKIGKIPIEV-ADVPGFFTTRFIEGWLLEAIRSFE 208
PRK08268 PRK08268
3-hydroxy-acyl-CoA dehydrogenase; Validated
 8-211 1.45e-26

3-hydroxy-acyl-CoA dehydrogenase; Validated


Pssm-ID: 236211 [Multi-domain]  Cd Length: 507  Bit Score: 106.08  E-value: 1.45e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   8 CVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEM-KLLE-------QAGSLKGSLSVEEQLSLISGCP 79
Cdd:PRK08268   9 TVAVIGAGAMGAGIAQVAAQAGHTVLLYDARAGAAAAARDGIAARLaKLVEkgkltaeQADAALARLRPVEALADLADCD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  80 NIQEAVegamhiqecvPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQciVA--HPVNPPYYIPLVE 157
Cdd:PRK08268  89 LVVEAI----------VERLDVKQALFAQLEAIVSPDCILATNTSSLSITAIAAALKHPER--VAglHFFNPVPLMKLVE 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 530402420 158 LVPHPETAPTTVDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVE 211
Cdd:PRK08268 157 VVSGLATDPAVADALYALARAWGKTPVRA-KDTPGFIVNRAARPYYTEALRVLE 209
PLN02545 PLN02545
3-hydroxybutyryl-CoA dehydrogenase
 1-211 6.51e-25

3-hydroxybutyryl-CoA dehydrogenase


Pssm-ID: 215300 [Multi-domain]  Cd Length: 295  Bit Score: 99.03  E-value: 6.51e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   1 MASSAAgcVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSlSVEEQLSLISGCPN 80
Cdd:PLN02545   1 MAEIKK--VGVVGAGQMGSGIAQLAAAAGMDVWLLDSDPAALSRGLDSISSSLARLVKKGKMSQE-EADATLGRIRCTTN 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  81 IQEaVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVP 160
Cdd:PLN02545  78 LEE-LRDADFIIEAIVESEDLKKKLFSELDRICKPSAILASNTSSISITRLASATQRPQQVIGMHFMNPPPIMKLVEIIR 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 530402420 161 HPETAPTTVDRTHALMKKIGQCPMRVQkEVAGFVLNRLQYAIISEAWRLVE 211
Cdd:PLN02545 157 GADTSDEVFDATKALAERFGKTVVCSQ-DYPGFIVNRILMPMINEAFYALY 206
PRK07530 PRK07530
3-hydroxybutyryl-CoA dehydrogenase; Validated
 9-206 4.76e-20

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181018 [Multi-domain]  Cd Length: 292  Bit Score: 85.83  E-value: 4.76e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKllEQAGslKGSLSVEEQ---LSLISGCPNIQEAV 85
Cdd:PRK07530   7 VGVIGAGQMGNGIAHVCALAGYDVLLNDVSADRLEAGLATINGNLA--RQVA--KGKISEEARaaaLARISTATDLEDLA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  86 EGAMHIqECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETA 165
Cdd:PRK07530  83 DCDLVI-EAATEDETVKRKIFAQLCPVLKPEAILATNTSSISITRLASATDRPERFIGIHFMNPVPVMKLVELIRGIATD 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 530402420 166 PTTVDRTHALMKKIGQCPMrVQKEVAGFVLNRLQYAIISEA 206
Cdd:PRK07530 162 EATFEAAKEFVTKLGKTIT-VAEDFPAFIVNRILLPMINEA 201
PRK07819 PRK07819
3-hydroxybutyryl-CoA dehydrogenase; Validated
 9-211 7.59e-16

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181133 [Multi-domain]  Cd Length: 286  Bit Score: 74.25  E-value: 7.59e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEmklLEQAGSlKGSLSVEEQ---LSLISGCPNIQEAV 85
Cdd:PRK07819   8 VGVVGAGQMGAGIAEVCARAGVDVLVFETTEELATAGRNRIEKS---LERAVS-RGKLTERERdaaLARLRFTTDLGDFA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  86 EGAMHIqECVPEDLELKKKIFAQLDSII-DDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPET 164
Cdd:PRK07819  84 DRQLVI-EAVVEDEAVKTEIFAELDKVVtDPDAVLASNTSSIPIMKLAAATKRPGRVLGLHFFNPVPVLPLVELVPTLVT 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 530402420 165 APTTVDRTHALMKKI-GQCPMRVQKEvAGFVLNRLQYAIISEAWRLVE 211
Cdd:PRK07819 163 SEATVARAEEFASDVlGKQVVRAQDR-SGFVVNALLVPYLLSAIRMVE 209
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
9-210 9.98e-16

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 75.32  E-value: 9.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420   9 VVIVGSGVIGRSWAMLFAS-GGFQVKLYDIEQQQIRNALENI---------RKEMKLLEQagslkgslsvEEQLSLISGC 78
Cdd:PRK11154 312 VGVLGGGLMGGGIAYVTATkAGLPVRIKDINPQGINHALKYSwdlldkkvkRRHLKPSER----------DKQMALISGT 381

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402420  79 PNIQeAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVEL 158
Cdd:PRK11154 382 TDYR-GFKHADVVIEAVFEDLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEV 460

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530402420 159 VPHPETAPTTVDRTHALMKKIGQCPMrVQKEVAGFVLNRLQYAIISEAWRLV 210
Cdd:PRK11154 461 IPHAKTSAETIATTVALAKKQGKTPI-VVRDGAGFYVNRILAPYINEAARLL 511
3HCDH pfam00725
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ...
 192-211 6.75e-04

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.


Pssm-ID: 395588 [Multi-domain]  Cd Length: 97  Bit Score: 37.58  E-value: 6.75e-04
                          10        20
                  ....*....|....*....|
gi 530402420  192 GFVLNRLQYAIISEAWRLVE 211
Cdd:pfam00725   1 GFVVNRLLAPYLNEAIRLVE 20
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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