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Conserved domains on  [gi|530399970|ref|XP_005268796|]
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bridge-like lipid transfer protein family member 3B isoform X2 [Homo sapiens]

Protein Classification

bridge-like lipid transfer protein( domain architecture ID 10576535)

bridge-like lipid transfer protein similar to Homo sapiens bridge-like lipid transfer protein family member 3A/3B, which acts as tube-forming lipid transport protein that mediates the transfer of lipids between membranes at organelle contact sites

Gene Ontology:  GO:0120009|GO:0120013
PubMed:  35491307
TCDB:  1.R.2.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Chorein_N pfam12624
N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein ...
 1-96 1.06e-16

N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein sorting 13A (VPS13A) protein in vertebrates lead to the disease of chorea-acanthocytosis, the exact function of any of the regions within the protein is not yet known. This region is the proposed leucine zipper at the N-terminus. The full-length protein is a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport.


:

Pssm-ID: 463646  Cd Length: 116  Bit Score: 77.22  E-value: 1.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399970     1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLqNMLDLPtwLAINKVFCNKASIRIPWTKLKTHPI 80
Cdd:pfam12624    1 LESLVASLLNRYLGEYVENLDPDQLKVGLWSGDVVLENLKLKKEAL-DKLDLP--IEVKSGHIGKLTLKIPWTNLKSEPV 77

                           90
                   ....*....|....*.
gi 530399970    81 CLSLDKVIMEMSTCEE 96
Cdd:pfam12624   78 VIEIEDVYLLAVPKDE 93
 
Name Accession Description Interval E-value
Chorein_N pfam12624
N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein ...
 1-96 1.06e-16

N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein sorting 13A (VPS13A) protein in vertebrates lead to the disease of chorea-acanthocytosis, the exact function of any of the regions within the protein is not yet known. This region is the proposed leucine zipper at the N-terminus. The full-length protein is a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport.


Pssm-ID: 463646  Cd Length: 116  Bit Score: 77.22  E-value: 1.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399970     1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLqNMLDLPtwLAINKVFCNKASIRIPWTKLKTHPI 80
Cdd:pfam12624    1 LESLVASLLNRYLGEYVENLDPDQLKVGLWSGDVVLENLKLKKEAL-DKLDLP--IEVKSGHIGKLTLKIPWTNLKSEPV 77

                           90
                   ....*....|....*.
gi 530399970    81 CLSLDKVIMEMSTCEE 96
Cdd:pfam12624   78 VIEIEDVYLLAVPKDE 93
 
Name Accession Description Interval E-value
Chorein_N pfam12624
N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein ...
 1-96 1.06e-16

N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein sorting 13A (VPS13A) protein in vertebrates lead to the disease of chorea-acanthocytosis, the exact function of any of the regions within the protein is not yet known. This region is the proposed leucine zipper at the N-terminus. The full-length protein is a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport.


Pssm-ID: 463646  Cd Length: 116  Bit Score: 77.22  E-value: 1.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530399970     1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLqNMLDLPtwLAINKVFCNKASIRIPWTKLKTHPI 80
Cdd:pfam12624    1 LESLVASLLNRYLGEYVENLDPDQLKVGLWSGDVVLENLKLKKEAL-DKLDLP--IEVKSGHIGKLTLKIPWTNLKSEPV 77

                           90
                   ....*....|....*.
gi 530399970    81 CLSLDKVIMEMSTCEE 96
Cdd:pfam12624   78 VIEIEDVYLLAVPKDE 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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