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Conserved domains on  [gi|530366188|ref|XP_005273181|]
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laminin subunit beta-3 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LamNT smart00136
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ...
20-248 9.68e-84

Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.


:

Pssm-ID: 214532  Cd Length: 238  Bit Score: 272.31  E-value: 9.68e-84
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188     20 ACSRGACYPPVGDLLVGRtrFLRASSTCGLTKPETYCTQ--YGEWQMKCCKCDSRQPHnyYSHRVENVASSSGP--MRWW 95
Cdd:smart00136    1 AGRPRSCYPPFVNLAFGR--EVTATSTCGEPGPERYCKLvgHTEQGKKCDYCDARNPR--RSHPAENLTDGNNPnnPTWW 76
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188     96 QSQNDVNP---VSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSsDFGKTWRVYQYLAADCTSTFPRVRQGRPQS--WQD 170
Cdd:smart00136   77 QSEPLSNGpqnVNLTLDLGKEFHVTYVILKFCSPRPSLWILERS-DFGKTWQPWQYFSSDCRRTFGRPPRGPITKgnEDE 155
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    171 VRCQSLPQRPNaRLNGGKVQLNLMDLVSGIP-ATQSQKIQEVGEITNLRVNFTRLAPVPQRGYH-----PPSAYYAVSQL 244
Cdd:smart00136  156 VICTSEYSDIV-PLEGGEIAFSLLEGRPSATdFDNSPVLQEWVTATNIRVRLTRLRTLGDELMDdrpevTRRYYYAISDI 234

                    ....
gi 530366188    245 RLQG 248
Cdd:smart00136  235 AVGG 238
cc_LAMB3_C cd22303
C-terminal coiled-coil domain found in laminin subunit beta-3 (LAMB3); LAMB3 is also called ...
1102-1172 4.90e-36

C-terminal coiled-coil domain found in laminin subunit beta-3 (LAMB3); LAMB3 is also called epiligrin subunit beta, kalinin B1 chain, kalinin subunit beta, laminin B1k chain, laminin-5 subunit beta, or nicein subunit beta. It is a major component of the basement membrane in most adult tissues. Mutations in LAMB3 are associated with Herlitz junctional epidermolysis bullosa (H-JEB), a severe autosomal recessive disorder characterized by blister formation within the dermal-epidermal basement membrane. LAMB3 is a component of laminin, a complex glycoprotein consisting of three different polypeptide chains (alpha, beta, gamma). Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. This model corresponds to the C-terminal coiled-coil domain of LAMB3, which may be involved in the integrin binding activity.


:

Pssm-ID: 411974 [Multi-domain]  Cd Length: 71  Bit Score: 130.64  E-value: 4.90e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530366188 1102 GARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
Cdd:cd22303     1 GERVANIKKEAESLFKETSDMMKRMKDIETELQEGAQALEGKSARLLGLEEQVEKIRDDINNRVTYYSTCK 71
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
379-428 1.04e-14

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 69.30  E-value: 1.04e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 530366188   379 CECDPDGAVpGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Cdd:pfam00053    1 CDCNPHGSL-SDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
534-576 6.96e-12

Laminin-type epidermal growth factor-like domai;


:

Pssm-ID: 214543  Cd Length: 46  Bit Score: 61.17  E-value: 6.96e-12
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 530366188    534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYP 576
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGP 43
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
431-478 2.15e-11

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 59.67  E-value: 2.15e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 530366188   431 CDCNILGSRRDmPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA--SGQGC 478
Cdd:pfam00053    1 CDCNPHGSLSD-TCDPETGQCLCKPGVTGRHCDRCKPGYYGLPsdPPQGC 49
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
838-1092 5.60e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 5.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  838 QLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDvrrtRLLIQQVRdfltdpdtdaATIQEVSEAVL 917
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQ----------AEEYELLAELA 298
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  918 ALwlPTDSATVLQKMNEIQAIAARLpnvdlvLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEA 997
Cdd:COG1196   299 RL--EQDIARLEERRRELEERLEEL------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  998 QDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEG 1077
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
                         250
                  ....*....|....*
gi 530366188 1078 FERIKQKYAELKDRL 1092
Cdd:COG1196   451 EAELEEEEEALLELL 465
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
481-534 6.78e-10

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 55.44  E-value: 6.78e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 530366188   481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSaaairQCPDRTYGDVATGCRAC 534
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCD-----RCKPGYYGLPSDPPQGC 49
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
249-304 4.54e-08

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


:

Pssm-ID: 238012  Cd Length: 50  Bit Score: 50.43  E-value: 4.54e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530366188  249 SCFCHGHAD---RCAPKPGasagpstavqvhdVCVCQHNTAGPNCERCAPFYNNRPWRP 304
Cdd:cd00055     1 PCDCNGHGSlsgQCDPGTG-------------QCECKPNTTGRRCDRCAPGYYGLPSQG 46
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
316-366 3.24e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


:

Pssm-ID: 395007  Cd Length: 49  Bit Score: 42.34  E-value: 3.24e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 530366188   316 CDCNGH---SETCHFdpavfaasqgaYGGVCDnCRDHTEGKNCERCQLHYFRNR 366
Cdd:pfam00053    1 CDCNPHgslSDTCDP-----------ETGQCL-CKPGVTGRHCDRCKPGYYGLP 42
GumC super family cl34566
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
626-980 3.89e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3206:

Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 3.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  626 DAKSKIEQIRAVLSSPAVTEQEVAQVASAILsLRRTLQGLQLDlpleEETLSLPRDLESLDRSFNGLLTMYQRKREQFEK 705
Cdd:COG3206    65 SSDVLLSGLSSLSASDSPLETQIEILKSRPV-LERVVDKLNLD----EDPLGEEASREAAIERLRKNLTVEPVKGSNVIE 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  706 IS--SADPSGAFRM---LSTAYEQSaQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGgggtgspKLVALRLEmsslpdl 780
Cdd:COG3206   140 ISytSPDPELAAAVanaLAEAYLEQ-NLELRREEARKALEFLEEQLPELRKELEEAEA-------ALEEFRQK------- 204
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  781 tptfNKLcgnsrqmactpISCPGElcpqdngtacgsrcrgvlpraggaflmAGQVAEQLRGFNAQLQRTRQMIRAAEESA 860
Cdd:COG3206   205 ----NGL-----------VDLSEE---------------------------AKLLLQQLSELESQLAEARAELAEAEARL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  861 SQIQS----------------SAQRLETQVSASRSQMEE----------DVRRTRLLIQQVRDFLtdpDTDAATIQEVSE 914
Cdd:COG3206   243 AALRAqlgsgpdalpellqspVIQQLRAQLAELEAELAElsarytpnhpDVIALRAQIAALRAQL---QQEAQRILASLE 319
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  915 AVLALwLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARR----LQAEAEEARSRAHAVEGQV 980
Cdd:COG3206   320 AELEA-LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARElyesLLQRLEEARLAEALTVGNV 388
 
Name Accession Description Interval E-value
LamNT smart00136
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ...
20-248 9.68e-84

Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.


Pssm-ID: 214532  Cd Length: 238  Bit Score: 272.31  E-value: 9.68e-84
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188     20 ACSRGACYPPVGDLLVGRtrFLRASSTCGLTKPETYCTQ--YGEWQMKCCKCDSRQPHnyYSHRVENVASSSGP--MRWW 95
Cdd:smart00136    1 AGRPRSCYPPFVNLAFGR--EVTATSTCGEPGPERYCKLvgHTEQGKKCDYCDARNPR--RSHPAENLTDGNNPnnPTWW 76
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188     96 QSQNDVNP---VSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSsDFGKTWRVYQYLAADCTSTFPRVRQGRPQS--WQD 170
Cdd:smart00136   77 QSEPLSNGpqnVNLTLDLGKEFHVTYVILKFCSPRPSLWILERS-DFGKTWQPWQYFSSDCRRTFGRPPRGPITKgnEDE 155
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    171 VRCQSLPQRPNaRLNGGKVQLNLMDLVSGIP-ATQSQKIQEVGEITNLRVNFTRLAPVPQRGYH-----PPSAYYAVSQL 244
Cdd:smart00136  156 VICTSEYSDIV-PLEGGEIAFSLLEGRPSATdFDNSPVLQEWVTATNIRVRLTRLRTLGDELMDdrpevTRRYYYAISDI 234

                    ....
gi 530366188    245 RLQG 248
Cdd:smart00136  235 AVGG 238
Laminin_N pfam00055
Laminin N-terminal (Domain VI);
26-248 3.14e-58

Laminin N-terminal (Domain VI);


Pssm-ID: 459653  Cd Length: 230  Bit Score: 200.50  E-value: 3.14e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    26 CYPPVGDLLVGRTrfLRASSTCGLTKPETYCTQygEWQM---KCCKCDSRQPHNyySHRVENVASSSG--PMRWWQSQND 100
Cdd:pfam00055    1 CYPAFGNLAFGRE--VSATSTCGLNGPERYCIL--SGLEggkKCFICDSRDPHN--SHPPSNLTDSNNgtNETWWQSETG 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   101 VNP---VSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSW-QDVRC--- 173
Cdd:pfam00055   75 VIQyenVNLTLDLGKEFHFTYLILKFKSPRPAAMVLERSTDFGKTWQPYQYFASDCRRTFGRPSGPSRGIKdDEVICtse 154
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   174 QSLPqRPnarLNGGKVQLNLMDLVSGIP-ATQSQKIQEVGEITNLRVNFTRLA--PVPQRGYHP--PSAYYAVSQLRLQG 248
Cdd:pfam00055  155 YSDI-SP---LTGGEVIFSTLEGRPSANiFDYSPELQDWLTATNIRIRLLRLHtlGDELLDDPSvlRKYYYAISDISVGG 230
cc_LAMB3_C cd22303
C-terminal coiled-coil domain found in laminin subunit beta-3 (LAMB3); LAMB3 is also called ...
1102-1172 4.90e-36

C-terminal coiled-coil domain found in laminin subunit beta-3 (LAMB3); LAMB3 is also called epiligrin subunit beta, kalinin B1 chain, kalinin subunit beta, laminin B1k chain, laminin-5 subunit beta, or nicein subunit beta. It is a major component of the basement membrane in most adult tissues. Mutations in LAMB3 are associated with Herlitz junctional epidermolysis bullosa (H-JEB), a severe autosomal recessive disorder characterized by blister formation within the dermal-epidermal basement membrane. LAMB3 is a component of laminin, a complex glycoprotein consisting of three different polypeptide chains (alpha, beta, gamma). Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. This model corresponds to the C-terminal coiled-coil domain of LAMB3, which may be involved in the integrin binding activity.


Pssm-ID: 411974 [Multi-domain]  Cd Length: 71  Bit Score: 130.64  E-value: 4.90e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530366188 1102 GARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
Cdd:cd22303     1 GERVANIKKEAESLFKETSDMMKRMKDIETELQEGAQALEGKSARLLGLEEQVEKIRDDINNRVTYYSTCK 71
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
379-428 1.04e-14

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 69.30  E-value: 1.04e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 530366188   379 CECDPDGAVpGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Cdd:pfam00053    1 CDCNPHGSL-SDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
379-428 5.28e-13

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 64.25  E-value: 5.28e-13
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|
gi 530366188    379 CECDPDGAVPGApCDPVTGQCVCKEHVQGERCDLCKPGFTGltyANPQGC 428
Cdd:smart00180    1 CDCDPGGSASGT-CDPDTGQCECKPNVTGRRCDRCAPGYYG---DGPPGC 46
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
378-429 1.59e-12

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 63.14  E-value: 1.59e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 530366188  378 SCECDPDGAVPGApCDPVTGQCVCKEHVQGERCDLCKPGFTGLTyANPQGCH 429
Cdd:cd00055     1 PCDCNGHGSLSGQ-CDPGTGQCECKPNTTGRRCDRCAPGYYGLP-SQGGGCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
534-576 6.96e-12

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 61.17  E-value: 6.96e-12
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 530366188    534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYP 576
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGP 43
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
533-582 1.72e-11

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 60.06  E-value: 1.72e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 530366188  533 ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACH 582
Cdd:cd00055     1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
431-478 2.15e-11

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 59.67  E-value: 2.15e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 530366188   431 CDCNILGSRRDmPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA--SGQGC 478
Cdd:pfam00053    1 CDCNPHGSLSD-TCDPETGQCLCKPGVTGRHCDRCKPGYYGLPsdPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
534-571 2.61e-11

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 59.67  E-value: 2.61e-11
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 530366188   534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
430-479 2.76e-11

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 59.68  E-value: 2.76e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 530366188  430 RCDCNILGSRRDmPCDEESGRCLCLPNVVGPKCDQCAPYHWKLAS-GQGCE 479
Cdd:cd00055     1 PCDCNGHGSLSG-QCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSqGGGCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
431-478 8.83e-11

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 58.09  E-value: 8.83e-11
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 530366188    431 CDCNILGSRrDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKlASGQGC 478
Cdd:smart00180    1 CDCDPGGSA-SGTCDPDTGQCECKPNVTGRRCDRCAPGYYG-DGPPGC 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
838-1092 5.60e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 5.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  838 QLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDvrrtRLLIQQVRdfltdpdtdaATIQEVSEAVL 917
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQ----------AEEYELLAELA 298
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  918 ALwlPTDSATVLQKMNEIQAIAARLpnvdlvLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEA 997
Cdd:COG1196   299 RL--EQDIARLEERRRELEERLEEL------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  998 QDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEG 1077
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
                         250
                  ....*....|....*
gi 530366188 1078 FERIKQKYAELKDRL 1092
Cdd:COG1196   451 EAELEEEEEALLELL 465
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
481-534 6.78e-10

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 55.44  E-value: 6.78e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 530366188   481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSaaairQCPDRTYGDVATGCRAC 534
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCD-----RCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
481-531 7.52e-10

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 55.40  E-value: 7.52e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|.
gi 530366188    481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSaaairQCPDRTYGDVATGC 531
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCD-----RCAPGYYGDGPPGC 46
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
480-532 2.16e-09

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.28  E-value: 2.16e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530366188  480 PCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSaaairQCPDRTYGD--VATGCR 532
Cdd:cd00055     1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCD-----RCAPGYYGLpsQGGGCQ 50
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
844-1071 5.19e-09

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 58.45  E-value: 5.19e-09
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    844 AQLQRTRQMIRAAEESASQIQSSAQRLET------QVSASRSQMEEDVRRTRLLIQQ----VRDFLTDPDTDAATIQEVS 913
Cdd:smart00283    1 DVSEAVEEIAAGAEEQAEELEELAERMEElsasieEVAANADEIAATAQSAAEAAEEgreaVEDAITAMDQIREVVEEAV 80
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    914 EAVLALwlpTDSATVLQKMNE-IQAIAarlpnvdlvlSQTkqDI---------ARA--------------RRL----QAE 965
Cdd:smart00283   81 SAVEEL---EESSDEIGEIVSvIDDIA----------DQT--NLlalnaaieaARAgeagrgfavvadevRKLaersAES 145
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    966 AEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLrpaEKLVTSMTKQ---LGDFWTR 1042
Cdd:smart00283  146 AKEIESLIKEIQEETNEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLV---QEIAAATDEQaagSEEVNAA 222
                           250       260
                    ....*....|....*....|....*....
gi 530366188   1043 MEELRHQARQQGAEAVQAQQLAEGASEQA 1071
Cdd:smart00283  223 IDEIAQVTQETAAMSEEISAAAEELSGLA 251
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
834-1158 7.70e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 7.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEdvRRTRLL-----IQQVRDFLTDPDTDAAT 908
Cdd:PRK02224  332 ECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVED--RREEIEeleeeIEELRERFGDAPVDLGN 409
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  909 IQEVSEAVLAlwlptdsatvlqkmnEIQAIAARLPNVDLVLSQTKQDIARARRLQAE------------------AEEAR 970
Cdd:PRK02224  410 AEDFLEELRE---------------ERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvetIEEDR 474
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  971 SRAHAVEGQVEDvvgnLRQGTVALQEAQDTMQgtsrSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQA 1050
Cdd:PRK02224  475 ERVEELEAELED----LEEEVEEVEERLERAE----DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERA 546
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1051 RQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELfGETMEMMDRMKDME 1130
Cdd:PRK02224  547 AELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERL-REKREALAELNDER 625
                         330       340       350
                  ....*....|....*....|....*....|
gi 530366188 1131 LELLRGSQAimlRSADLTGL--EKRVEQIR 1158
Cdd:PRK02224  626 RERLAEKRE---RKRELEAEfdEARIEEAR 652
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
249-304 4.54e-08

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 50.43  E-value: 4.54e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530366188  249 SCFCHGHAD---RCAPKPGasagpstavqvhdVCVCQHNTAGPNCERCAPFYNNRPWRP 304
Cdd:cd00055     1 PCDCNGHGSlsgQCDPGTG-------------QCECKPNTTGRRCDRCAPGYYGLPSQG 46
PspA_IM30 pfam04012
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...
951-1127 1.05e-06

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.


Pssm-ID: 461130 [Multi-domain]  Cd Length: 215  Bit Score: 50.83  E-value: 1.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   951 QTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQE-AQDTMQGTSRSL--------RLIQDRVAEVQQV 1021
Cdd:pfam04012   26 MLEQAIRDMQSELVKARQALAQTIARQKQLERRLEQQTEQAKKLEEkAQAALTKGNEELarealaekKSLEKQAEALETQ 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1022 LRPAEKLVTSMTKQLGDFWTRMEELRHQ-----ARQQGAEAVQAQQLAEGASEQAlSAQEGFERIKQKYAELKDRLGQSS 1096
Cdd:pfam04012  106 LAQQRSAVEQLRKQLAALETKIQQLKAKknllkARLKAAKAQEAVQTSLGSLSTS-SATDSFERIEEKIEEREARADAAA 184
                          170       180       190
                   ....*....|....*....|....*....|.
gi 530366188  1097 MLGEQGARIQSVKtEAEELFGETMEMMDRMK 1127
Cdd:pfam04012  185 ELASAVDLDAKLE-QAGIQMEVSEDVLARLK 214
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
838-1158 1.05e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 1.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   838 QLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRtrlliqqvrdfltdpdtdaatIQEVSEAVL 917
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE---------------------IEELQKELY 291
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   918 ALwlptdSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARR----LQAEAEEARSRAHAVEGQVEDVVGNLRQGTVA 993
Cdd:TIGR02168  292 AL-----ANEISRLEQQKQILRERLANLERQLEELEAQLEELESkldeLAEELAELEEKLEELKEELESLEAELEELEAE 366
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   994 LQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQ------QLAEGA 1067
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqaELEELE 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1068 SEQAlSAQEGFERIKQKYAELKDRLGQSSmlgeqgARIQSVKTEAEELFGEtMEMMDRMKDMELELLRGSQAIMLRSADL 1147
Cdd:TIGR02168  447 EELE-ELQEELERLEEALEELREELEEAE------QALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKALLKNQSGL 518
                          330
                   ....*....|..
gi 530366188  1148 TGLEKRV-EQIR 1158
Cdd:TIGR02168  519 SGILGVLsELIS 530
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
250-307 8.77e-06

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 43.88  E-value: 8.77e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 530366188   250 CFCHGHADRcapkpgasagPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEG 307
Cdd:pfam00053    1 CDCNPHGSL----------SDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQG 48
growth_prot_Scy NF041483
polarized growth protein Scy;
847-1128 1.56e-05

polarized growth protein Scy;


Pssm-ID: 469371 [Multi-domain]  Cd Length: 1293  Bit Score: 49.44  E-value: 1.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  847 QRTRQMIRAAEESASQIQSSAQRLETQ----VSASRSQMEEDVRRTRLLIQQVRDFL-TD-------PDTDAATI----Q 910
Cdd:NF041483  764 RRATELVSAAEQTAQQVRDSVAGLQEQaeeeIAGLRSAAEHAAERTRTEAQEEADRVrSDayaererASEDANRLrreaQ 843
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  911 EVSEAVLALWLPTdsatvlqkMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGqvedvvGNLRQG 990
Cdd:NF041483  844 EETEAAKALAERT--------VSEAIAEAERLRSDASEYAQRVRTEASDTLASAEQDAARTRADARED------ANRIRS 909
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  991 TVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSmtkqlgdfwtRMEELRHQARQQGAEAV-QAQQLAEGASE 1069
Cdd:NF041483  910 DAAAQADRLIGEATSEAERLTAEARAEAERLRDEARAEAER----------VRADAAAQAEQLIAEATgEAERLRAEAAE 979
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530366188 1070 QALSAQEGFERIKQKYAELKdrlgqssmlgeqgariQSVKTEAEELFGETMEMMDRMKD 1128
Cdd:NF041483  980 TVGSAQQHAERIRTEAERVK----------------AEAAAEAERLRTEAREEADRTLD 1022
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
316-366 3.24e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 42.34  E-value: 3.24e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 530366188   316 CDCNGH---SETCHFdpavfaasqgaYGGVCDnCRDHTEGKNCERCQLHYFRNR 366
Cdd:pfam00053    1 CDCNPHgslSDTCDP-----------ETGQCL-CKPGVTGRHCDRCKPGYYGLP 42
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
315-369 3.45e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 42.34  E-value: 3.45e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 530366188  315 RCDCNGH---SETCHFDpavfaasqgayGGVCDnCRDHTEGKNCERCQLHYFRNRRPG 369
Cdd:cd00055     1 PCDCNGHgslSGQCDPG-----------TGQCE-CKPNTTGRRCDRCAPGYYGLPSQG 46
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
862-1076 5.30e-05

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 45.69  E-value: 5.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  862 QIQSSAQrletQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLalwlptdsatvlQKMNEIQAIAAR 941
Cdd:cd11386     2 ELSASIE----EVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAV------------SAVEELEESSAE 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  942 LPNVdlvlSQTKQDIAR-----ArrLQAEAEEAR----SRAHAVegqVEDVVGNLrqgtvalqeAQDTMQGT---SRSLR 1009
Cdd:cd11386    66 IGEI----VEVIDDIAEqtnllA--LNAAIEAARageaGRGFAV---VADEVRKL---------AEESAEAAkeiEELIE 127
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530366188 1010 LIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQgaeAVQAQQLAEGASEQALSAQE 1076
Cdd:cd11386   128 EIQEQTEEAVEAMEETSEEVEEGVELVEETGRAFEEIVASVEEV---ADGIQEISAATQEQSASTQE 191
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
620-1160 6.14e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.35  E-value: 6.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   620 LASRILDAKSKIEQIRAVLSSPAVT--------EQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNg 691
Cdd:TIGR00606  417 LQSKERLKQEQADEIRDEKKGLGRTielkkeilEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSL- 495
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   692 llTMYQRKREQFEKISSADPSGAFRMLSTAYEQsaqaaqqvsdssrlLDQLRDSRREAERLVR-------QAGGGGGTGS 764
Cdd:TIGR00606  496 --TETLKKEVKSLQNEKADLDRKLRKLDQEMEQ--------------LNHHTTTRTQMEMLTKdkmdkdeQIRKIKSRHS 559
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   765 PKLVALRLEMSSLPDLTPTFNKLCGNSRQMActpiscpgelcpqdngtacgSRCRGVLPRAGGAFLMAGQVAEQLRGFNA 844
Cdd:TIGR00606  560 DELTSLLGYFPNKKQLEDWLHSKSKEINQTR--------------------DRLAKLNKELASLEQNKNHINNELESKEE 619
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   845 QLQRTRQMIRAAEeSASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQV---------------RDFLTD-------- 901
Cdd:TIGR00606  620 QLSSYEDKLFDVC-GSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFItqltdenqsccpvcqRVFQTEaelqefis 698
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   902 ---------PDTDAATIQEVS------EAVLALwLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRL---- 962
Cdd:TIGR00606  699 dlqsklrlaPDKLKSTESELKkkekrrDEMLGL-APGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLlgti 777
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   963 QAEAEEARSRAHAV------EGQVEDVVGNLRQGTVALQ--EAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTK 1034
Cdd:TIGR00606  778 MPEEESAKVCLTDVtimerfQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE 857
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1035 QLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAE-LKDRLGQSSMLGEQGARIQSVKTE-- 1111
Cdd:TIGR00606  858 QIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQdSPLETFLEKDQQEKEELISSKETSnk 937
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 530366188  1112 -AEELFGETMEMMDR----MKDMELELLRGSQ-AIMLRSADLTGLEKRVEQIRDH 1160
Cdd:TIGR00606  938 kAQDKVNDIKEKVKNihgyMKDIENKIQDGKDdYLKQKETELNTVNAQLEECEKH 992
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
278-302 1.46e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 40.37  E-value: 1.46e-04
                            10        20
                    ....*....|....*....|....*
gi 530366188    278 VCVCQHNTAGPNCERCAPFYNNRPW 302
Cdd:smart00180   19 QCECKPNVTGRRCDRCAPGYYGDGP 43
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
316-369 2.39e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 39.60  E-value: 2.39e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 530366188    316 CDCNG---HSETCHFDpavfaasqgayGGVCDnCRDHTEGKNCERCQLHYFRNRRPG 369
Cdd:smart00180    1 CDCDPggsASGTCDPD-----------TGQCE-CKPNVTGRRCDRCAPGYYGDGPPG 45
growth_prot_Scy NF041483
polarized growth protein Scy;
834-1139 3.47e-04

polarized growth protein Scy;


Pssm-ID: 469371 [Multi-domain]  Cd Length: 1293  Bit Score: 44.82  E-value: 3.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSA-QRLETQVSASRSQMEEdvrRTRLLIQQVRDFLTDPDTDAATIQEV 912
Cdd:NF041483  255 QAAELSRAAEQRMQEAEEALREARAEAEKVVAEAkEAAAKQLASAESANEQ---RTRTAKEEIARLVGEATKEAEALKAE 331
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  913 SEAVLA------------------LWLPTDSATVLQKmneiqaiAARlpNVDLVLSQTKQDiARAR-----------RLQ 963
Cdd:NF041483  332 AEQALAdaraeaeklvaeaaekarTVAAEDTAAQLAK-------AAR--TAEEVLTKASED-AKATtraaaeeaeriRRE 401
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  964 AEAEEARSRAHAVE------GQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRliQDRVAE------------VQQV---L 1022
Cdd:NF041483  402 AEAEADRLRGEAADqaeqlkGAAKDDTKEYRAKTVELQEEARRLRGEAEQLR--AEAVAEgerirgearreaVQQIeeaA 479
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1023 RPAEKLV-----------------------------TSMTKQLGDfwtRMEELRHQARQQGAEAV-QAQQLAEGASEQAL 1072
Cdd:NF041483  480 RTAEELLtkakadadelrstataeservrteaieraTTLRRQAEE---TLERTRAEAERLRAEAEeQAEEVRAAAERAAR 556
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530366188 1073 SAQEGFER-IKQKYAELKDRLGQ-----SSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQA 1139
Cdd:NF041483  557 ELREETERaIAARQAEAAEELTRlhteaEERLTAAEEALADARAEAERIRREAAEETERLRTEAAERIRTLQA 629
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
626-980 3.89e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 3.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  626 DAKSKIEQIRAVLSSPAVTEQEVAQVASAILsLRRTLQGLQLDlpleEETLSLPRDLESLDRSFNGLLTMYQRKREQFEK 705
Cdd:COG3206    65 SSDVLLSGLSSLSASDSPLETQIEILKSRPV-LERVVDKLNLD----EDPLGEEASREAAIERLRKNLTVEPVKGSNVIE 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  706 IS--SADPSGAFRM---LSTAYEQSaQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGgggtgspKLVALRLEmsslpdl 780
Cdd:COG3206   140 ISytSPDPELAAAVanaLAEAYLEQ-NLELRREEARKALEFLEEQLPELRKELEEAEA-------ALEEFRQK------- 204
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  781 tptfNKLcgnsrqmactpISCPGElcpqdngtacgsrcrgvlpraggaflmAGQVAEQLRGFNAQLQRTRQMIRAAEESA 860
Cdd:COG3206   205 ----NGL-----------VDLSEE---------------------------AKLLLQQLSELESQLAEARAELAEAEARL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  861 SQIQS----------------SAQRLETQVSASRSQMEE----------DVRRTRLLIQQVRDFLtdpDTDAATIQEVSE 914
Cdd:COG3206   243 AALRAqlgsgpdalpellqspVIQQLRAQLAELEAELAElsarytpnhpDVIALRAQIAALRAQL---QQEAQRILASLE 319
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  915 AVLALwLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARR----LQAEAEEARSRAHAVEGQV 980
Cdd:COG3206   320 AELEA-LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARElyesLLQRLEEARLAEALTVGNV 388
growth_prot_Scy NF041483
polarized growth protein Scy;
833-1126 5.46e-03

polarized growth protein Scy;


Pssm-ID: 469371 [Multi-domain]  Cd Length: 1293  Bit Score: 40.96  E-value: 5.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  833 GQVAEQ-LRgfNAQLQrTRQMIRAAEESASQIQSSAQRL--ETQVSASRSQME---EDVRRTRLLIQQVRDfltdpdtDA 906
Cdd:NF041483   71 GYQAEQlLR--NAQIQ-ADQLRADAERELRDARAQTQRIlqEHAEHQARLQAElhtEAVQRRQQLDQELAE-------RR 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  907 ATIQ-EVSEAVLalWlptdsATVLQKMNEIQAiaARLpnVDLVLSQTKQDIARAR------------RLQAEAEEARSRA 973
Cdd:NF041483  141 QTVEsHVNENVA--W-----AEQLRARTESQA--RRL--LDESRAEAEQALAAARaeaerlaeearqRLGSEAESARAEA 209
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  974 HAVEGQV-EDVVGNLRQGTVALQEAqdtmqgTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQ 1052
Cdd:NF041483  210 EAILRRArKDAERLLNAASTQAQEA------TDHAEQLRSSTAAESDQARRQAAELSRAAEQRMQEAEEALREARAEAEK 283
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530366188 1053 QGAEAVQ--AQQL--AEGASEQalsaqegfeRIKQKYAELkdrlgqSSMLGEQGARIQSVKTEAEELFGETMEMMDRM 1126
Cdd:NF041483  284 VVAEAKEaaAKQLasAESANEQ---------RTRTAKEEI------ARLVGEATKEAEALKAEAEQALADARAEAEKL 346
 
Name Accession Description Interval E-value
LamNT smart00136
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ...
20-248 9.68e-84

Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.


Pssm-ID: 214532  Cd Length: 238  Bit Score: 272.31  E-value: 9.68e-84
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188     20 ACSRGACYPPVGDLLVGRtrFLRASSTCGLTKPETYCTQ--YGEWQMKCCKCDSRQPHnyYSHRVENVASSSGP--MRWW 95
Cdd:smart00136    1 AGRPRSCYPPFVNLAFGR--EVTATSTCGEPGPERYCKLvgHTEQGKKCDYCDARNPR--RSHPAENLTDGNNPnnPTWW 76
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188     96 QSQNDVNP---VSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSsDFGKTWRVYQYLAADCTSTFPRVRQGRPQS--WQD 170
Cdd:smart00136   77 QSEPLSNGpqnVNLTLDLGKEFHVTYVILKFCSPRPSLWILERS-DFGKTWQPWQYFSSDCRRTFGRPPRGPITKgnEDE 155
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    171 VRCQSLPQRPNaRLNGGKVQLNLMDLVSGIP-ATQSQKIQEVGEITNLRVNFTRLAPVPQRGYH-----PPSAYYAVSQL 244
Cdd:smart00136  156 VICTSEYSDIV-PLEGGEIAFSLLEGRPSATdFDNSPVLQEWVTATNIRVRLTRLRTLGDELMDdrpevTRRYYYAISDI 234

                    ....
gi 530366188    245 RLQG 248
Cdd:smart00136  235 AVGG 238
Laminin_N pfam00055
Laminin N-terminal (Domain VI);
26-248 3.14e-58

Laminin N-terminal (Domain VI);


Pssm-ID: 459653  Cd Length: 230  Bit Score: 200.50  E-value: 3.14e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    26 CYPPVGDLLVGRTrfLRASSTCGLTKPETYCTQygEWQM---KCCKCDSRQPHNyySHRVENVASSSG--PMRWWQSQND 100
Cdd:pfam00055    1 CYPAFGNLAFGRE--VSATSTCGLNGPERYCIL--SGLEggkKCFICDSRDPHN--SHPPSNLTDSNNgtNETWWQSETG 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   101 VNP---VSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSW-QDVRC--- 173
Cdd:pfam00055   75 VIQyenVNLTLDLGKEFHFTYLILKFKSPRPAAMVLERSTDFGKTWQPYQYFASDCRRTFGRPSGPSRGIKdDEVICtse 154
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   174 QSLPqRPnarLNGGKVQLNLMDLVSGIP-ATQSQKIQEVGEITNLRVNFTRLA--PVPQRGYHP--PSAYYAVSQLRLQG 248
Cdd:pfam00055  155 YSDI-SP---LTGGEVIFSTLEGRPSANiFDYSPELQDWLTATNIRIRLLRLHtlGDELLDDPSvlRKYYYAISDISVGG 230
cc_LAMB3_C cd22303
C-terminal coiled-coil domain found in laminin subunit beta-3 (LAMB3); LAMB3 is also called ...
1102-1172 4.90e-36

C-terminal coiled-coil domain found in laminin subunit beta-3 (LAMB3); LAMB3 is also called epiligrin subunit beta, kalinin B1 chain, kalinin subunit beta, laminin B1k chain, laminin-5 subunit beta, or nicein subunit beta. It is a major component of the basement membrane in most adult tissues. Mutations in LAMB3 are associated with Herlitz junctional epidermolysis bullosa (H-JEB), a severe autosomal recessive disorder characterized by blister formation within the dermal-epidermal basement membrane. LAMB3 is a component of laminin, a complex glycoprotein consisting of three different polypeptide chains (alpha, beta, gamma). Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. This model corresponds to the C-terminal coiled-coil domain of LAMB3, which may be involved in the integrin binding activity.


Pssm-ID: 411974 [Multi-domain]  Cd Length: 71  Bit Score: 130.64  E-value: 4.90e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530366188 1102 GARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
Cdd:cd22303     1 GERVANIKKEAESLFKETSDMMKRMKDIETELQEGAQALEGKSARLLGLEEQVEKIRDDINNRVTYYSTCK 71
cc_LAMB_C cd22295
C-terminal coiled-coil domain found in the laminin subunit beta (LAMB) family; The LAMB family ...
1102-1171 7.69e-24

C-terminal coiled-coil domain found in the laminin subunit beta (LAMB) family; The LAMB family contains four members, LAMB1-4. They are components of laminin, a complex glycoprotein consisting of three different polypeptide chains (alpha, beta, gamma). Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. This model corresponds to the C-terminal coiled-coil domain of LAMB, which may be involved in the integrin binding activity.


Pssm-ID: 411969 [Multi-domain]  Cd Length: 70  Bit Score: 95.81  E-value: 7.69e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1102 GARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATC 1171
Cdd:cd22295     1 RDRAEKLKKEAEDLLKKANEKLKRLKDLERKFEANEQAMEEKAAELQELEKRVNELLDYIREKVSAYATC 70
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
379-428 1.04e-14

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 69.30  E-value: 1.04e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 530366188   379 CECDPDGAVpGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Cdd:pfam00053    1 CDCNPHGSL-SDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
379-428 5.28e-13

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 64.25  E-value: 5.28e-13
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|
gi 530366188    379 CECDPDGAVPGApCDPVTGQCVCKEHVQGERCDLCKPGFTGltyANPQGC 428
Cdd:smart00180    1 CDCDPGGSASGT-CDPDTGQCECKPNVTGRRCDRCAPGYYG---DGPPGC 46
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
378-429 1.59e-12

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 63.14  E-value: 1.59e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 530366188  378 SCECDPDGAVPGApCDPVTGQCVCKEHVQGERCDLCKPGFTGLTyANPQGCH 429
Cdd:cd00055     1 PCDCNGHGSLSGQ-CDPGTGQCECKPNTTGRRCDRCAPGYYGLP-SQGGGCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
534-576 6.96e-12

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 61.17  E-value: 6.96e-12
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 530366188    534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYP 576
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGP 43
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
533-582 1.72e-11

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 60.06  E-value: 1.72e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 530366188  533 ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACH 582
Cdd:cd00055     1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGGCQ 50
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
431-478 2.15e-11

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 59.67  E-value: 2.15e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 530366188   431 CDCNILGSRRDmPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA--SGQGC 478
Cdd:pfam00053    1 CDCNPHGSLSD-TCDPETGQCLCKPGVTGRHCDRCKPGYYGLPsdPPQGC 49
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
534-571 2.61e-11

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 59.67  E-value: 2.61e-11
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 530366188   534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
430-479 2.76e-11

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 59.68  E-value: 2.76e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 530366188  430 RCDCNILGSRRDmPCDEESGRCLCLPNVVGPKCDQCAPYHWKLAS-GQGCE 479
Cdd:cd00055     1 PCDCNGHGSLSG-QCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSqGGGCQ 50
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
431-478 8.83e-11

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 58.09  E-value: 8.83e-11
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 530366188    431 CDCNILGSRrDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKlASGQGC 478
Cdd:smart00180    1 CDCDPGGSA-SGTCDPDTGQCECKPNVTGRRCDRCAPGYYG-DGPPGC 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
838-1092 5.60e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 5.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  838 QLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDvrrtRLLIQQVRdfltdpdtdaATIQEVSEAVL 917
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQ----------AEEYELLAELA 298
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  918 ALwlPTDSATVLQKMNEIQAIAARLpnvdlvLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEA 997
Cdd:COG1196   299 RL--EQDIARLEERRRELEERLEEL------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  998 QDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEG 1077
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
                         250
                  ....*....|....*
gi 530366188 1078 FERIKQKYAELKDRL 1092
Cdd:COG1196   451 EAELEEEEEALLELL 465
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
481-534 6.78e-10

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 55.44  E-value: 6.78e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 530366188   481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSaaairQCPDRTYGDVATGCRAC 534
Cdd:pfam00053    1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCD-----RCKPGYYGLPSDPPQGC 49
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
481-531 7.52e-10

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 55.40  E-value: 7.52e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|.
gi 530366188    481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSaaairQCPDRTYGDVATGC 531
Cdd:smart00180    1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCD-----RCAPGYYGDGPPGC 46
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
480-532 2.16e-09

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 54.28  E-value: 2.16e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530366188  480 PCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSaaairQCPDRTYGD--VATGCR 532
Cdd:cd00055     1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCD-----RCAPGYYGLpsQGGGCQ 50
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
834-1109 2.81e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 2.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVsasrSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVS 913
Cdd:COG1196   257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL----ARLEQDIARLEERRRELEERLEELEEELAELEEEL 332
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  914 EAvlalwlptDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVA 993
Cdd:COG1196   333 EE--------LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  994 LQEAQDTMQGtsRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLgdfwtrmEELRHQARQQGAEAVQAQQLAEGASEQALS 1073
Cdd:COG1196   405 LEEAEEALLE--RLERLEEELEELEEALAELEEEEEEEEEALE-------EAAEEEAELEEEEEALLELLAELLEEAALL 475
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 530366188 1074 AQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVK 1109
Cdd:COG1196   476 EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
844-1071 5.19e-09

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 58.45  E-value: 5.19e-09
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    844 AQLQRTRQMIRAAEESASQIQSSAQRLET------QVSASRSQMEEDVRRTRLLIQQ----VRDFLTDPDTDAATIQEVS 913
Cdd:smart00283    1 DVSEAVEEIAAGAEEQAEELEELAERMEElsasieEVAANADEIAATAQSAAEAAEEgreaVEDAITAMDQIREVVEEAV 80
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    914 EAVLALwlpTDSATVLQKMNE-IQAIAarlpnvdlvlSQTkqDI---------ARA--------------RRL----QAE 965
Cdd:smart00283   81 SAVEEL---EESSDEIGEIVSvIDDIA----------DQT--NLlalnaaieaARAgeagrgfavvadevRKLaersAES 145
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188    966 AEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLrpaEKLVTSMTKQ---LGDFWTR 1042
Cdd:smart00283  146 AKEIESLIKEIQEETNEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLV---QEIAAATDEQaagSEEVNAA 222
                           250       260
                    ....*....|....*....|....*....
gi 530366188   1043 MEELRHQARQQGAEAVQAQQLAEGASEQA 1071
Cdd:smart00283  223 IDEIAQVTQETAAMSEEISAAAEELSGLA 251
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
834-1158 7.70e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 7.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEdvRRTRLL-----IQQVRDFLTDPDTDAAT 908
Cdd:PRK02224  332 ECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVED--RREEIEeleeeIEELRERFGDAPVDLGN 409
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  909 IQEVSEAVLAlwlptdsatvlqkmnEIQAIAARLPNVDLVLSQTKQDIARARRLQAE------------------AEEAR 970
Cdd:PRK02224  410 AEDFLEELRE---------------ERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvetIEEDR 474
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  971 SRAHAVEGQVEDvvgnLRQGTVALQEAQDTMQgtsrSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQA 1050
Cdd:PRK02224  475 ERVEELEAELED----LEEEVEEVEERLERAE----DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERA 546
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1051 RQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELfGETMEMMDRMKDME 1130
Cdd:PRK02224  547 AELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERL-REKREALAELNDER 625
                         330       340       350
                  ....*....|....*....|....*....|
gi 530366188 1131 LELLRGSQAimlRSADLTGL--EKRVEQIR 1158
Cdd:PRK02224  626 RERLAEKRE---RKRELEAEfdEARIEEAR 652
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
833-1082 3.05e-08

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 57.72  E-value: 3.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  833 GQVAEQLRGFNAQLQRTRQMIR--------AAEESASQIQSSAQRLETQ------VSASRSQMEEDVRRTRLLIQQVRDF 898
Cdd:COG0840   238 GQLADAFNRMIENLRELVGQVResaeqvasASEELAASAEELAAGAEEQaasleeTAAAMEELSATVQEVAENAQQAAEL 317
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  899 LTDPDTDAATIQEVSEAVLALW--LPTDSATVLQKMNEIQAIAARLPN-VDLVlsqtkQDI---------------ARA- 959
Cdd:COG0840   318 AEEASELAEEGGEVVEEAVEGIeeIRESVEETAETIEELGESSQEIGEiVDVI-----DDIaeqtnllalnaaieaARAg 392
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  960 -------------RRLqAE-----AEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEV--- 1018
Cdd:COG0840   393 eagrgfavvadevRKL-AErsaeaTKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVsdl 471
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530366188 1019 -QQVLRPAEKLVTSmTKQLGdfwTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIK 1082
Cdd:COG0840   472 iQEIAAASEEQSAG-TEEVN---QAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFK 532
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
249-304 4.54e-08

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 50.43  E-value: 4.54e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530366188  249 SCFCHGHAD---RCAPKPGasagpstavqvhdVCVCQHNTAGPNCERCAPFYNNRPWRP 304
Cdd:cd00055     1 PCDCNGHGSlsgQCDPGTG-------------QCECKPNTTGRRCDRCAPGYYGLPSQG 46
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
616-1116 8.78e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 8.78e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  616 EDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRRTLQGLQLDL---PLEEETLSLPRDLESLDRSFNGL 692
Cdd:COG4717    72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLqllPLYQELEALEAELAELPERLEEL 151
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  693 LTMYQRKREQFEKISSAdpSGAFRMLSTAYEQ-----SAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGgggtgspKL 767
Cdd:COG4717   152 EERLEELRELEEELEEL--EAELAELQEELEElleqlSLATEEELQDLAEELEELQQRLAELEEELEEAQE-------EL 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  768 VALRLEMSSLPDLTPTFNKLcgNSRQMACTPISCPGELCPQDngTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQ 847
Cdd:COG4717   223 EELEEELEQLENELEAAALE--ERLKEARLLLLIAAALLALL--GLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKA 298
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  848 RTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLalwlptdsat 927
Cdd:COG4717   299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEL---------- 368
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  928 vlqkMNEIQAIAARLpNVDlvlsqTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQdtmqgtsrs 1007
Cdd:COG4717   369 ----EQEIAALLAEA-GVE-----DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--------- 429
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1008 lrlIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAE--GASEQALSAQEGFERIKQKY 1085
Cdd:COG4717   430 ---LEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAElrELAEEWAALKLALELLEEAR 506
                         490       500       510
                  ....*....|....*....|....*....|.
gi 530366188 1086 AELKDRlgqssmlgeqgaRIQSVKTEAEELF 1116
Cdd:COG4717   507 EEYREE------------RLPPVLERASEYF 525
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
593-1158 1.14e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 1.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  593 REQALRF----GRLRNATASLWsgpGLEDRGLASRILDAKSKIEQIRAVLsspAVTEQEVAQVASAILSLRRTLQGLQLD 668
Cdd:COG1196   209 AEKAERYrelkEELKELEAELL---LLKLRELEAELEELEAELEELEAEL---EELEAELAELEAELEELRLELEELELE 282
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  669 L-PLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRmLSTAYEQSAQAAQQVSDSSRLLDQLRDSRR 747
Cdd:COG1196   283 LeEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE-LEELEEELEELEEELEEAEEELEEAEAELA 361
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  748 EAERLVRQAGGgggtgspKLVALRLEMSSLpdltptfnklcgNSRQMActpiscpgelcPQDNGTACGSRCRGVLPRAGG 827
Cdd:COG1196   362 EAEEALLEAEA-------ELAEAEEELEEL------------AEELLE-----------ALRAAAELAAQLEELEEAEEA 411
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  828 AFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDfLTDPDTDAA 907
Cdd:COG1196   412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE-LLEELAEAA 490
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  908 TIQEVSEAVLALWLPTDSATVLQKMNEIQ-----------------------AIAARLPNV---------DLVLSQTKQD 955
Cdd:COG1196   491 ARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavavligveaayeaaleaALAAALQNIvveddevaaAAIEYLKAAK 570
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  956 IARARRLQAEAEEARS--RAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMT 1033
Cdd:COG1196   571 AGRATFLPLDKIRARAalAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1034 KQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAE 1113
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*
gi 530366188 1114 ELfgETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIR 1158
Cdd:COG1196   731 EA--EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
828-1086 3.95e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 3.95e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  828 AFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQM---EEDVRRTRLLIQQVRDFLTDPDT 904
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIaalARRIRALEQELAALEAELAELEK 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  905 DAATIQ---EVSEAVLALWLPTdsatvLQKMNeiqaiaaRLPNVDLVLSQT--KQDIARARRLQAEAEEARSRAHAVEGQ 979
Cdd:COG4942    91 EIAELRaelEAQKEELAELLRA-----LYRLG-------RQPPLALLLSPEdfLDAVRRLQYLKYLAPARREQAEELRAD 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  980 VEDvvgnLRQGTVALQEAQDTMQgtsRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQ 1059
Cdd:COG4942   159 LAE----LAALRAELEAERAELE---ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
                         250       260
                  ....*....|....*....|....*..
gi 530366188 1060 AQQLAEGASEQALSAqeGFERIKQKYA 1086
Cdd:COG4942   232 LEAEAAAAAERTPAA--GFAALKGKLP 256
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
832-1162 5.51e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 5.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  832 AGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSAsrsqmEEDVRRTRLLIQQVRDFLTDPDTDAATIQE 911
Cdd:COG4717    83 AEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL-----LPLYQELEALEAELAELPERLEELEERLEE 157
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  912 VSEAVLAlwLPTDSATVLQKMNEIQAIAARLPNVDLV-LSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQG 990
Cdd:COG4717   158 LRELEEE--LEELEAELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  991 TVALQEAQD---------------TMQGTSRSLRLIQDRVAEVQQ-VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQqg 1054
Cdd:COG4717   236 LEAAALEERlkearlllliaaallALLGLGGSLLSLILTIAGVLFlVLGLLALLFLLLAREKASLGKEAEELQALPAL-- 313
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1055 aEAVQAQQLAEGASEQALSAQEGFERIKQKY---AELKDRLGQSSMLGEQgARIQSVKTEAEELFGET------------ 1119
Cdd:COG4717   314 -EELEEEELEELLAALGLPPDLSPEELLELLdriEELQELLREAEELEEE-LQLEELEQEIAALLAEAgvedeeelraal 391
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 530366188 1120 ------MEMMDRMKDME--LELLRGSQAIMLRSADLTGLEKRVEQIRDHIN 1162
Cdd:COG4717   392 eqaeeyQELKEELEELEeqLEELLGELEELLEALDEEELEEELEELEEELE 442
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
692-1172 8.97e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 8.97e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  692 LLTMYQRKREQFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGggggtgspKLVALR 771
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELE--------ELREEL 118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  772 LEMSSLPDLTPTFNKLCGNSRQMActpiscpgelcpqdngtacgsrcrgvlpraggaflmagQVAEQLRGFNAQLQRTRQ 851
Cdd:COG4717   119 EKLEKLLQLLPLYQELEALEAELA--------------------------------------ELPERLEELEERLEELRE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  852 M---IRAAEESASQIQSSAQRLETQVSASR----SQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTD 924
Cdd:COG4717   161 LeeeLEELEAELAELQEELEELLEQLSLATeeelQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  925 SATVLQKMNEIQAIAARLpnvdLVLSQTKQDIARARRLQAEAeearsrAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGT 1004
Cdd:COG4717   241 LEERLKEARLLLLIAAAL----LALLGLGGSLLSLILTIAGV------LFLVLGLLALLFLLLAREKASLGKEAEELQAL 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1005 SRSLRLIQDRVAEVQQVLRPAEKLVTSMT-------KQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASE------QA 1071
Cdd:COG4717   311 PALEELEEEELEELLAALGLPPDLSPEELlelldriEELQELLREAEELEEELQLEELEQEIAALLAEAGVEdeeelrAA 390
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1072 LSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQS---VKTEAEELFGETMEMMDRMKDMELELLRGSQAI--MLRSAD 1146
Cdd:COG4717   391 LEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeeLEEELEELEEELEELEEELEELREELAELEAELeqLEEDGE 470
                         490       500
                  ....*....|....*....|....*.
gi 530366188 1147 LTGLEKRVEQIRDHINGRVLYYATCK 1172
Cdd:COG4717   471 LAELLQELEELKAELRELAEEWAALK 496
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
828-1108 9.00e-07

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 53.10  E-value: 9.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  828 AFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAA 907
Cdd:COG0840    77 ALVVLLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAA 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  908 TIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQ--TKQDIARARRLQAEAEEARSR--AHAVEGQVEDV 983
Cdd:COG0840   157 AAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALllSRSITRPLRELLEVLERIAEGdlTVRIDVDSKDE 236
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  984 VGNLRQgtvALQEAQDTMQGTSRSLRLIQDRVAE-VQQVLRPAEKLVTSMTKQ---LGDFWTRMEELRHQARQQGAEAVQ 1059
Cdd:COG0840   237 IGQLAD---AFNRMIENLRELVGQVRESAEQVASaSEELAASAEELAAGAEEQaasLEETAAAMEELSATVQEVAENAQQ 313
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 530366188 1060 AQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSS----MLGEQGARIQSV 1108
Cdd:COG0840   314 AAELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAetieELGESSQEIGEI 366
PspA_IM30 pfam04012
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...
951-1127 1.05e-06

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.


Pssm-ID: 461130 [Multi-domain]  Cd Length: 215  Bit Score: 50.83  E-value: 1.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   951 QTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQE-AQDTMQGTSRSL--------RLIQDRVAEVQQV 1021
Cdd:pfam04012   26 MLEQAIRDMQSELVKARQALAQTIARQKQLERRLEQQTEQAKKLEEkAQAALTKGNEELarealaekKSLEKQAEALETQ 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1022 LRPAEKLVTSMTKQLGDFWTRMEELRHQ-----ARQQGAEAVQAQQLAEGASEQAlSAQEGFERIKQKYAELKDRLGQSS 1096
Cdd:pfam04012  106 LAQQRSAVEQLRKQLAALETKIQQLKAKknllkARLKAAKAQEAVQTSLGSLSTS-SATDSFERIEEKIEEREARADAAA 184
                          170       180       190
                   ....*....|....*....|....*....|.
gi 530366188  1097 MLGEQGARIQSVKtEAEELFGETMEMMDRMK 1127
Cdd:pfam04012  185 ELASAVDLDAKLE-QAGIQMEVSEDVLARLK 214
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
838-1158 1.05e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 1.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   838 QLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRtrlliqqvrdfltdpdtdaatIQEVSEAVL 917
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE---------------------IEELQKELY 291
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   918 ALwlptdSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARR----LQAEAEEARSRAHAVEGQVEDVVGNLRQGTVA 993
Cdd:TIGR02168  292 AL-----ANEISRLEQQKQILRERLANLERQLEELEAQLEELESkldeLAEELAELEEKLEELKEELESLEAELEELEAE 366
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   994 LQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQ------QLAEGA 1067
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqaELEELE 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1068 SEQAlSAQEGFERIKQKYAELKDRLGQSSmlgeqgARIQSVKTEAEELFGEtMEMMDRMKDMELELLRGSQAIMLRSADL 1147
Cdd:TIGR02168  447 EELE-ELQEELERLEEALEELREELEEAE------QALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKALLKNQSGL 518
                          330
                   ....*....|..
gi 530366188  1148 TGLEKRV-EQIR 1158
Cdd:TIGR02168  519 SGILGVLsELIS 530
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
834-1075 1.13e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 52.14  E-value: 1.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEdvrRTRLLIQQVRDFLTDpDTDAATIQEVS 913
Cdd:COG3883    34 AAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE---RREELGERARALYRS-GGSVSYLDVLL 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  914 EAvlalwlpTDSATVLQKMNeiqaiaarlpNVDLVLSQTKQDIARARRLQAEAEEARSrahavegQVEDVVGNLRQGTVA 993
Cdd:COG3883   110 GS-------ESFSDFLDRLS----------ALSKIADADADLLEELKADKAELEAKKA-------ELEAKLAELEALKAE 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  994 LQEAQDTMQGTsrslrliqdrVAEvqqvlrpAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALS 1073
Cdd:COG3883   166 LEAAKAELEAQ----------QAE-------QEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAA 228

                  ..
gi 530366188 1074 AQ 1075
Cdd:COG3883   229 AA 230
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
936-1166 1.21e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 52.21  E-value: 1.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  936 QAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRV 1015
Cdd:COG4372    24 ILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEEL 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1016 AEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQS 1095
Cdd:COG4372   104 ESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQ 183
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530366188 1096 --SMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVL 1166
Cdd:COG4372   184 alDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVI 256
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
821-1135 1.31e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 52.59  E-value: 1.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   821 VLPRAggaFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT 900
Cdd:pfam07888   25 VVPRA---ELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEE 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   901 DPDTDAATIQEVSEAVLALW------------LPTDSATVLQKMNEIQAIAARLPN-VDLVLSQTKQDIARARRLQAEAE 967
Cdd:pfam07888  102 KYKELSASSEELSEEKDALLaqraahearireLEEDIKTLTQRVLERETELERMKErAKKAGAQRKEEEAERKQLQAKLQ 181
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   968 EARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAE----------VQQVLRPAEKLVTSMTKQLG 1037
Cdd:pfam07888  182 QTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAEnealleelrsLQERLNASERKVEGLGEELS 261
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1038 DFWTR----MEELrHQARQQGAEAvqAQQLAegasEQALSAQEGferiKQKYAELKDRLGQSSMLGEQgaRIQSVKTE-- 1111
Cdd:pfam07888  262 SMAAQrdrtQAEL-HQARLQAAQL--TLQLA----DASLALREG----RARWAQERETLQQSAEADKD--RIEKLSAElq 328
                          330       340
                   ....*....|....*....|....*
gi 530366188  1112 -AEELFGEtmEMMDRMKdMELELLR 1135
Cdd:pfam07888  329 rLEERLQE--ERMEREK-LEVELGR 350
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
909-1164 2.27e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 2.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   909 IQEVSEAVLALwlpTDSATVLQKmnEIQAIAARLPNVDLVLSQTKQDIARARR----LQAEAEEARSRAHAVEGQVEDVV 984
Cdd:TIGR02168  679 IEELEEKIEEL---EEKIAELEK--ALAELRKELEELEEELEQLRKELEELSRqisaLRKDLARLEAEVEQLEERIAQLS 753
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   985 GNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDF--------------WTRMEELRHQA 1050
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELraeltllneeaanlRERLESLERRI 833
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1051 RQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRL-GQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDM 1129
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELeALLNERASLEEALALLRSELEELSEELRELESKRSEL 913
                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 530366188  1130 E--LELLRGSQAIMlrSADLTGLEKRVEQIRDHINGR 1164
Cdd:TIGR02168  914 RreLEELREKLAQL--ELRLEGLEVRIDNLQERLSEE 948
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
820-1163 4.93e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 50.29  E-value: 4.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  820 GVLPRAGgafLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFL 899
Cdd:COG4372    17 GLRPKTG---ILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQ 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  900 TDPDTDAATIQEVSEAvlalwlptdsATVLQKmnEIQAIAARLPNVDLVLSQTKQDIArarRLQAEAEEARSRAHAVEGQ 979
Cdd:COG4372    94 AELAQAQEELESLQEE----------AEELQE--ELEELQKERQDLEQQRKQLEAQIA---ELQSEIAEREEELKELEEQ 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  980 VEdvvgNLRQGTVALQEAQDTMqgtsrslrLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARqqgaEAVQ 1059
Cdd:COG4372   159 LE----SLQEELAALEQELQAL--------SEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAE----ELLE 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1060 AQQLAEGASEQALSAQEGFERiKQKYAELKDRLGQSSMLGEQGARIQsVKTEAEELFGETMEMMDRMKDMELELLRGSQA 1139
Cdd:COG4372   223 AKDSLEAKLGLALSALLDALE-LEEDKEELLEEVILKEIEELELAIL-VEKDTEEEELEIAALELEALEEAALELKLLAL 300
                         330       340
                  ....*....|....*....|....
gi 530366188 1140 IMLRSADLTGLEKRVEQIRDHING 1163
Cdd:COG4372   301 LLNLAALSLIGALEDALLAALLEL 324
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
958-1159 5.91e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 5.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  958 RARRLQAEAEE------------ARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPA 1025
Cdd:COG1196   214 RYRELKEELKEleaellllklreLEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1026 EKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQS-SMLGEQGAR 1104
Cdd:COG1196   294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAeEALLEAEAE 373
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530366188 1105 IQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRD 1159
Cdd:COG1196   374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE 428
PspA COG1842
Phage shock protein A [Transcription, Signal transduction mechanisms];
956-1114 6.81e-06

Phage shock protein A [Transcription, Signal transduction mechanisms];


Pssm-ID: 441447 [Multi-domain]  Cd Length: 217  Bit Score: 48.28  E-value: 6.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  956 IARARRLQAEAEEARSRAHAVEGQVEDVvgnLRQG-----TVALQEAQDtmqgtsrslrlIQDRVAEVQQVLRPAEKLVT 1030
Cdd:COG1842    50 IANQKRLERQLEELEAEAEKWEEKARLA---LEKGredlaREALERKAE-----------LEAQAEALEAQLAQLEEQVE 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1031 SMTKQLGDFWTRMEELRHQ-----ARQQGAEA-VQAQQLAEGASEQalSAQEGFERIKQK------YAELKDRLGQSSML 1098
Cdd:COG1842   116 KLKEALRQLESKLEELKAKkdtlkARAKAAKAqEKVNEALSGIDSD--DATSALERMEEKieemeaRAEAAAELAAGDSL 193
                         170
                  ....*....|....*.
gi 530366188 1099 GEQGARIQSvKTEAEE 1114
Cdd:COG1842   194 DDELAELEA-DSEVED 208
cc_LAMB4_C cd22301
C-terminal coiled-coil domain found in laminin subunit beta-4 (LAMB4); LAMB4, also called ...
1104-1171 8.02e-06

C-terminal coiled-coil domain found in laminin subunit beta-4 (LAMB4); LAMB4, also called laminin beta-1-related protein, is a component of laminin, a complex glycoprotein consisting of three different polypeptide chains (alpha, beta, gamma). Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Mutations or loss of LAMB4 may be features of gastric and colorectal cancers. Reduced LAMB4 levels may contribute to colonic dysmotility associated with diverticulitis. This model corresponds to the C-terminal coiled-coil domain of LAMB4, which may be involved in the integrin binding activity.


Pssm-ID: 411972 [Multi-domain]  Cd Length: 70  Bit Score: 44.65  E-value: 8.02e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530366188 1104 RIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATC 1171
Cdd:cd22301     3 RLKNIKKEAENLAKEIEDKMKRIEDLEKRIQDLNKRKEDKANQLARLEKQVISLRKEIVERVEGYSTC 70
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
250-307 8.77e-06

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 43.88  E-value: 8.77e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 530366188   250 CFCHGHADRcapkpgasagPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEG 307
Cdd:pfam00053    1 CDCNPHGSL----------SDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQG 48
growth_prot_Scy NF041483
polarized growth protein Scy;
847-1128 1.56e-05

polarized growth protein Scy;


Pssm-ID: 469371 [Multi-domain]  Cd Length: 1293  Bit Score: 49.44  E-value: 1.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  847 QRTRQMIRAAEESASQIQSSAQRLETQ----VSASRSQMEEDVRRTRLLIQQVRDFL-TD-------PDTDAATI----Q 910
Cdd:NF041483  764 RRATELVSAAEQTAQQVRDSVAGLQEQaeeeIAGLRSAAEHAAERTRTEAQEEADRVrSDayaererASEDANRLrreaQ 843
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  911 EVSEAVLALWLPTdsatvlqkMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGqvedvvGNLRQG 990
Cdd:NF041483  844 EETEAAKALAERT--------VSEAIAEAERLRSDASEYAQRVRTEASDTLASAEQDAARTRADARED------ANRIRS 909
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  991 TVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSmtkqlgdfwtRMEELRHQARQQGAEAV-QAQQLAEGASE 1069
Cdd:NF041483  910 DAAAQADRLIGEATSEAERLTAEARAEAERLRDEARAEAER----------VRADAAAQAEQLIAEATgEAERLRAEAAE 979
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530366188 1070 QALSAQEGFERIKQKYAELKdrlgqssmlgeqgariQSVKTEAEELFGETMEMMDRMKD 1128
Cdd:NF041483  980 TVGSAQQHAERIRTEAERVK----------------AEAAAEAERLRTEAREEADRTLD 1022
Laminin_I pfam06008
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ...
820-1039 1.92e-05

Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.


Pssm-ID: 310534 [Multi-domain]  Cd Length: 258  Bit Score: 47.79  E-value: 1.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   820 GVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRL---ETQVSASRSQMEEDVRRTRLLIQQVR 896
Cdd:pfam06008    9 GALPAPYKINYNLENLTKQLQEYLSPENAHKIQIEILEKELSSLAQETEELqkkATQTLAKAQQVNAESERTLGHAKELA 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   897 DFLTDPDtdaATIQEVSEAVLALWLPTD---SATVLQKMNEIQAIAARLPNVDLVLSQT--KQDIARARRLQAEAEEARS 971
Cdd:pfam06008   89 EAIKNLI---DNIKEINEKVATLGENDFalpSSDLSRMLAEAQRMLGEIRSRDFGTQLQnaEAELKAAQDLLSRIQTWFQ 165
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   972 RAHA----VEGQVEDVVGN-----------LRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQvlrpaEKLVTSMT-KQ 1035
Cdd:pfam06008  166 SPQEenkaLANALRDSLAEyeaklsdlrelLREAAAKTRDANRLNLANQANLREFQRKKEEVSE-----QKNQLEETlKT 240

                   ....
gi 530366188  1036 LGDF 1039
Cdd:pfam06008  241 ARDS 244
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
858-1162 2.61e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.47  E-value: 2.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  858 ESASQIQSSAQRLETQVS--ASRSQMEEDVRRTRLliqqVRDFLTDPDTDAATIQEVSEAVlalwlptdSATVLQKMNEI 935
Cdd:COG3206    71 SGLSSLSASDSPLETQIEilKSRPVLERVVDKLNL----DEDPLGEEASREAAIERLRKNL--------TVEPVKGSNVI 138
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  936 Q--------AIAARLPN------VDLVLSQTKQDIARARR-LQAEAEEARSRAHAVEGQVEDvvgnLRQ--GTVALQEaq 998
Cdd:COG3206   139 EisytspdpELAAAVANalaeayLEQNLELRREEARKALEfLEEQLPELRKELEEAEAALEE----FRQknGLVDLSE-- 212
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  999 dTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDfwtrmeelrhqarqqgaeavqaqqlaEGASEQALSAQEGF 1078
Cdd:COG3206   213 -EAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS--------------------------GPDALPELLQSPVI 265
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1079 ERIKQKYAELKDRLGQ-SSMLGEQGARIQSVKTEAEELfgetmemmDRMKDMELELLRGSQAIMLRSAD--LTGLEKRVE 1155
Cdd:COG3206   266 QQLRAQLAELEAELAElSARYTPNHPDVIALRAQIAAL--------RAQLQQEAQRILASLEAELEALQarEASLQAQLA 337

                  ....*..
gi 530366188 1156 QIRDHIN 1162
Cdd:COG3206   338 QLEARLA 344
Laminin_EGF pfam00053
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
316-366 3.24e-05

Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.


Pssm-ID: 395007  Cd Length: 49  Bit Score: 42.34  E-value: 3.24e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 530366188   316 CDCNGH---SETCHFdpavfaasqgaYGGVCDnCRDHTEGKNCERCQLHYFRNR 366
Cdd:pfam00053    1 CDCNPHgslSDTCDP-----------ETGQCL-CKPGVTGRHCDRCKPGYYGLP 42
EGF_Lam cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ...
315-369 3.45e-05

Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies


Pssm-ID: 238012  Cd Length: 50  Bit Score: 42.34  E-value: 3.45e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 530366188  315 RCDCNGH---SETCHFDpavfaasqgayGGVCDnCRDHTEGKNCERCQLHYFRNRRPG 369
Cdd:cd00055     1 PCDCNGHgslSGQCDPG-----------TGQCE-CKPNTTGRRCDRCAPGYYGLPSQG 46
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
850-1091 3.58e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 3.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  850 RQMI---RAAEESASQIQSSAQRLEtqvsASRSQMEEDVRRTRLLIQqvrdfltdpdtdaatIQEVSEAVLALWlptdsa 926
Cdd:COG4913   214 REYMleePDTFEAADALVEHFDDLE----RAHEALEDAREQIELLEP---------------IRELAERYAAAR------ 268
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  927 tvlQKMNEIQAIAARLPnvdLVLSQTKQDIARAR---------RLQAEAEEARSRAHAVEGQVEDVVGNLRQ-GTVALQE 996
Cdd:COG4913   269 ---ERLAELEYLRAALR---LWFAQRRLELLEAEleelraelaRLEAELERLEARLDALREELDELEAQIRGnGGDRLEQ 342
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  997 AQDTMQGTSRSLRLIQDRVAEVQQVLRPAEkLVTSMTKQlgDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQE 1076
Cdd:COG4913   343 LEREIERLERELEERERRRARLEALLAALG-LPLPASAE--EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR 419
                         250
                  ....*....|....*
gi 530366188 1077 GFERIKQKYAELKDR 1091
Cdd:COG4913   420 ELRELEAEIASLERR 434
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
862-1076 5.30e-05

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 45.69  E-value: 5.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  862 QIQSSAQrletQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLalwlptdsatvlQKMNEIQAIAAR 941
Cdd:cd11386     2 ELSASIE----EVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAV------------SAVEELEESSAE 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  942 LPNVdlvlSQTKQDIAR-----ArrLQAEAEEAR----SRAHAVegqVEDVVGNLrqgtvalqeAQDTMQGT---SRSLR 1009
Cdd:cd11386    66 IGEI----VEVIDDIAEqtnllA--LNAAIEAARageaGRGFAV---VADEVRKL---------AEESAEAAkeiEELIE 127
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530366188 1010 LIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQgaeAVQAQQLAEGASEQALSAQE 1076
Cdd:cd11386   128 EIQEQTEEAVEAMEETSEEVEEGVELVEETGRAFEEIVASVEEV---ADGIQEISAATQEQSASTQE 191
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
620-1160 6.14e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.35  E-value: 6.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   620 LASRILDAKSKIEQIRAVLSSPAVT--------EQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNg 691
Cdd:TIGR00606  417 LQSKERLKQEQADEIRDEKKGLGRTielkkeilEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSL- 495
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   692 llTMYQRKREQFEKISSADPSGAFRMLSTAYEQsaqaaqqvsdssrlLDQLRDSRREAERLVR-------QAGGGGGTGS 764
Cdd:TIGR00606  496 --TETLKKEVKSLQNEKADLDRKLRKLDQEMEQ--------------LNHHTTTRTQMEMLTKdkmdkdeQIRKIKSRHS 559
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   765 PKLVALRLEMSSLPDLTPTFNKLCGNSRQMActpiscpgelcpqdngtacgSRCRGVLPRAGGAFLMAGQVAEQLRGFNA 844
Cdd:TIGR00606  560 DELTSLLGYFPNKKQLEDWLHSKSKEINQTR--------------------DRLAKLNKELASLEQNKNHINNELESKEE 619
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   845 QLQRTRQMIRAAEeSASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQV---------------RDFLTD-------- 901
Cdd:TIGR00606  620 QLSSYEDKLFDVC-GSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFItqltdenqsccpvcqRVFQTEaelqefis 698
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   902 ---------PDTDAATIQEVS------EAVLALwLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRL---- 962
Cdd:TIGR00606  699 dlqsklrlaPDKLKSTESELKkkekrrDEMLGL-APGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLlgti 777
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   963 QAEAEEARSRAHAV------EGQVEDVVGNLRQGTVALQ--EAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTK 1034
Cdd:TIGR00606  778 MPEEESAKVCLTDVtimerfQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE 857
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1035 QLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAE-LKDRLGQSSMLGEQGARIQSVKTE-- 1111
Cdd:TIGR00606  858 QIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQdSPLETFLEKDQQEKEELISSKETSnk 937
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 530366188  1112 -AEELFGETMEMMDR----MKDMELELLRGSQ-AIMLRSADLTGLEKRVEQIRDH 1160
Cdd:TIGR00606  938 kAQDKVNDIKEKVKNihgyMKDIENKIQDGKDdYLKQKETELNTVNAQLEECEKH 992
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
834-1165 6.62e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.48  E-value: 6.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   834 QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFltdpdtdaatIQEVS 913
Cdd:pfam01576  746 QLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDL----------QRELE 815
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   914 EAVLAlwlpTDSATVLQKMNEiqaiaARLPNVDLVLSQTKQDIARARRLQAEAEEARSrahavegQVEDVVGNLRQGTVA 993
Cdd:pfam01576  816 EARAS----RDEILAQSKESE-----KKLKNLEAELLQLQEDLAASERARRQAQQERD-------ELADEIASGASGKSA 879
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   994 LQEAQdtmqgtsrslRLIQDRVAEVQQVLRpAEKLVTSMTKQlgdfwtrmeelRHQARQQGAEAVQAQQLAEGASEQAL- 1072
Cdd:pfam01576  880 LQDEK----------RRLEARIAQLEEELE-EEQSNTELLND-----------RLRKSTLQVEQLTTELAAERSTSQKSe 937
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1073 SAQEGFERIKQkyaELKDRLGQ--SSMLGEQGARIQSVKTEAEELfGETMEMMDRMKDMELELLRGSQA----IMLRSAD 1146
Cdd:pfam01576  938 SARQQLERQNK---ELKAKLQEmeGTVKSKFKSSIAALEAKIAQL-EEQLEQESRERQAANKLVRRTEKklkeVLLQVED 1013
                          330       340
                   ....*....|....*....|...
gi 530366188  1147 ltglEKRV-EQIRDHI---NGRV 1165
Cdd:pfam01576 1014 ----ERRHaDQYKDQAekgNSRM 1032
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
834-1164 7.55e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 46.43  E-value: 7.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVS 913
Cdd:COG4372    42 KLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQ 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  914 EAVLALwlpTDSATVLQKmnEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSR--AHAVEGQVEDVVGNLRQGT 991
Cdd:COG4372   122 KERQDL---EQQRKQLEA--QIAELQSEIAEREEELKELEEQLESLQEELAALEQELQAlsEAEAEQALDELLKEANRNA 196
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  992 VALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSmtkqLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQA 1071
Cdd:COG4372   197 EKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALS----ALLDALELEEDKEELLEEVILKEIEELELAILVEKD 272
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1072 LSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFG----ETMEMMDRMKDMELELLRGSQAIMLRSADL 1147
Cdd:COG4372   273 TEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLaallELAKKLELALAILLAELADLLQLLLVGLLD 352
                         330
                  ....*....|....*..
gi 530366188 1148 TGLEKRVEQIRDHINGR 1164
Cdd:COG4372   353 NDVLELLSKGAEAGVAD 369
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
956-1159 8.25e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 8.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  956 IARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDtmqgtsrSLRLIQDRVAEVQQVLRPAEKLVTSMTKQ 1035
Cdd:COG1196   231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL-------ELEELELELEEAQAEEYELLAELARLEQD 303
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1036 LgdfwtrmeelRHQARQQGAEAVQAQQLAE---GASEQALSAQEGFERIKQKYAELKDRLGQSSmlgeqgARIQSVKTEA 1112
Cdd:COG1196   304 I----------ARLEERRRELEERLEELEEelaELEEELEELEEELEELEEELEEAEEELEEAE------AELAEAEEAL 367
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 530366188 1113 EELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRD 1159
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
831-1089 8.61e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.93  E-value: 8.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  831 MAGQVAEQL-RGFNAQLQRTRQmiRAAEESASQIQSSAQRLETQVSASRSQMEeDVRRTRLLIQqvrdfltdpdtdaati 909
Cdd:COG3206   149 LAAAVANALaEAYLEQNLELRR--EEARKALEFLEEQLPELRKELEEAEAALE-EFRQKNGLVD---------------- 209
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  910 qevseavlalwLPTDSATVLQKMNEIQAiaarlpnvDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQ 989
Cdd:COG3206   210 -----------LSEEAKLLLQQLSELES--------QLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRA 270
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  990 GTVALQEAQDTMQGTS-------RSLR-----LIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEA 1057
Cdd:COG3206   271 QLAELEAELAELSARYtpnhpdvIALRaqiaaLRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELE 350
                         250       260       270
                  ....*....|....*....|....*....|..
gi 530366188 1058 VQAQQLaegaSEQALSAQEGFERIKQKYAELK 1089
Cdd:COG3206   351 AELRRL----EREVEVARELYESLLQRLEEAR 378
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
841-1085 1.01e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  841 GFNA--QLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQmeedvrrtRLLIQQVRDFLTDpDTDAATIQEvseavla 918
Cdd:COG4913   605 GFDNraKLAALEAELAELEEELAEAEERLEALEAELDALQER--------REALQRLAEYSWD-EIDVASAER------- 668
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  919 lwlptdsaTVLQKMNEIQAIaaRLPNVDLvlsqtkqdiaraRRLQAEAEEARSRAHAVEGQvedvvgnlrqgtvaLQEAQ 998
Cdd:COG4913   669 --------EIAELEAELERL--DASSDDL------------AALEEQLEELEAELEELEEE--------------LDELK 712
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  999 DTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVtsmtkQLGDFWtRMEELRHQARQQGAEAVQAQQLA---EGASEQALSAQ 1075
Cdd:COG4913   713 GEIGRLEKELEQAEEELDELQDRLEAAEDLA-----RLELRA-LLEERFAAALGDAVERELRENLEeriDALRARLNRAE 786
                         250
                  ....*....|
gi 530366188 1076 EGFERIKQKY 1085
Cdd:COG4913   787 EELERAMRAF 796
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
278-302 1.46e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 40.37  E-value: 1.46e-04
                            10        20
                    ....*....|....*....|....*
gi 530366188    278 VCVCQHNTAGPNCERCAPFYNNRPW 302
Cdd:smart00180   19 QCECKPNVTGRRCDRCAPGYYGDGP 43
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
834-1057 1.66e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 1.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQ--RTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVrdfltdpDTDAATIQE 911
Cdd:COG3206   186 ELRKELEEAEAALEefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL-------GSGPDALPE 258
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  912 VSEavlalwlptdSATVLQKMNEIQAIAARLpnvDLVLSQTKQDIARARRLQAEAEEARSRahaVEGQVEDVVGNLRQGT 991
Cdd:COG3206   259 LLQ----------SPVIQQLRAQLAELEAEL---AELSARYTPNHPDVIALRAQIAALRAQ---LQQEAQRILASLEAEL 322
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530366188  992 VALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEA 1057
Cdd:COG3206   323 EALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNV 388
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
835-1135 1.82e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 44.90  E-value: 1.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  835 VAEQLRGFNAQLQRTRQMIRAAEESASQIQSsaqrletQVSASRSQMEEDVRRTRLLIQQVRDFltdpDTDAATIQEVSE 914
Cdd:COG1340    41 LAEKRDELNAQVKELREEAQELREKRDELNE-------KVKELKEERDELNEKLNELREELDEL----RKELAELNKAGG 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  915 avlalwlptdSATVLQKmnEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARsRAHAVEGQVEDVVGNLRQgtvaL 994
Cdd:COG1340   110 ----------SIDKLRK--EIERLEWRQQTEVLSPEEEKELVEKIKELEKELEKAK-KALEKNEKLKELRAELKE----L 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  995 QEAQDTmqgtsrslrlIQDRVAE-VQQvlrpAEKLVTSMTKQLGdfwtRMEELRHQARQQGAEAVQAQQLAEGASEQALS 1073
Cdd:COG1340   173 RKEAEE----------IHKKIKElAEE----AQELHEEMIELYK----EADELRKEADELHKEIVEAQEKADELHEEIIE 234
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530366188 1074 AQEGFERIKQKYAELKDRLGQSSMlGEQGARIQSVKTEAEELF--GETMEMMDRMKDMELELLR 1135
Cdd:COG1340   235 LQKELRELRKELKKLRKKQRALKR-EKEKEELEEKAEEIFEKLkkGEKLTTEELKLLQKSGLLE 297
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
936-1157 2.21e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 2.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   936 QAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVeGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRL--IQD 1013
Cdd:TIGR00618  222 QVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLL-KQLRARIEELRAQEAVLEETQERINRARKAAPLaaHIK 300
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1014 RVAEV-QQVLRPAEKLVTSMTKqlgdfwtrmeelRHQARQQGAEAVQAQQ--LAEGASEQALSAQEgfERIKQKYAELKD 1090
Cdd:TIGR00618  301 AVTQIeQQAQRIHTELQSKMRS------------RAKLLMKRAAHVKQQSsiEEQRRLLQTLHSQE--IHIRDAHEVATS 366
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530366188  1091 RLGQSSmlgEQGARIQSVKTEAEELfgETMEMMDRMKDMELELLRGSQAimlrSADLTGLEKRVEQI 1157
Cdd:TIGR00618  367 IREISC---QQHTLTQHIHTLQQQK--TTLTQKLQSLCKELDILQREQA----TIDTRTSAFRDLQG 424
EGF_Lam smart00180
Laminin-type epidermal growth factor-like domai;
316-369 2.39e-04

Laminin-type epidermal growth factor-like domai;


Pssm-ID: 214543  Cd Length: 46  Bit Score: 39.60  E-value: 2.39e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 530366188    316 CDCNG---HSETCHFDpavfaasqgayGGVCDnCRDHTEGKNCERCQLHYFRNRRPG 369
Cdd:smart00180    1 CDCDPggsASGTCDPD-----------TGQCE-CKPNVTGRRCDRCAPGYYGDGPPG 45
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
930-1162 2.54e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 2.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  930 QKMNEIQAIAARLPnvdlvlsQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLR 1009
Cdd:PRK03918  204 EVLREINEISSELP-------ELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1010 LIQDRVAEVQQvLRPAEKLVTSMTKQLGDF---WTRMEELRHQARQQgAEAVQAQ-QLAEGASEQALSAQEGFERIKQKY 1085
Cdd:PRK03918  277 ELEEKVKELKE-LKEKAEEYIKLSEFYEEYldeLREIEKRLSRLEEE-INGIEERiKELEEKEERLEELKKKLKELEKRL 354
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1086 AELKDRLGQSSMLGEQGARIQSVKT-----EAEELFGETMEMMDRMKDMELELLRGSQAImlrsadlTGLEKRVEQIRDH 1160
Cdd:PRK03918  355 EELEERHELYEEAKAKKEELERLKKrltglTPEKLEKELEELEKAKEEIEEEISKITARI-------GELKKEIKELKKA 427

                  ..
gi 530366188 1161 IN 1162
Cdd:PRK03918  428 IE 429
growth_prot_Scy NF041483
polarized growth protein Scy;
834-1139 3.47e-04

polarized growth protein Scy;


Pssm-ID: 469371 [Multi-domain]  Cd Length: 1293  Bit Score: 44.82  E-value: 3.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSA-QRLETQVSASRSQMEEdvrRTRLLIQQVRDFLTDPDTDAATIQEV 912
Cdd:NF041483  255 QAAELSRAAEQRMQEAEEALREARAEAEKVVAEAkEAAAKQLASAESANEQ---RTRTAKEEIARLVGEATKEAEALKAE 331
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  913 SEAVLA------------------LWLPTDSATVLQKmneiqaiAARlpNVDLVLSQTKQDiARAR-----------RLQ 963
Cdd:NF041483  332 AEQALAdaraeaeklvaeaaekarTVAAEDTAAQLAK-------AAR--TAEEVLTKASED-AKATtraaaeeaeriRRE 401
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  964 AEAEEARSRAHAVE------GQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRliQDRVAE------------VQQV---L 1022
Cdd:NF041483  402 AEAEADRLRGEAADqaeqlkGAAKDDTKEYRAKTVELQEEARRLRGEAEQLR--AEAVAEgerirgearreaVQQIeeaA 479
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1023 RPAEKLV-----------------------------TSMTKQLGDfwtRMEELRHQARQQGAEAV-QAQQLAEGASEQAL 1072
Cdd:NF041483  480 RTAEELLtkakadadelrstataeservrteaieraTTLRRQAEE---TLERTRAEAERLRAEAEeQAEEVRAAAERAAR 556
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530366188 1073 SAQEGFER-IKQKYAELKDRLGQ-----SSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQA 1139
Cdd:NF041483  557 ELREETERaIAARQAEAAEELTRlhteaEERLTAAEEALADARAEAERIRREAAEETERLRTEAAERIRTLQA 629
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
894-1092 3.57e-04

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 43.20  E-value: 3.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  894 QVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATV---LQKMNEIQA-IAARLPNVDLVLSQTKQdiaRARRLQAEAEEA 969
Cdd:cd00176     1 KLQQFLRDADELEAWLSEKEELLSSTDYGDDLESVealLKKHEALEAeLAAHEERVEALNELGEQ---LIEEGHPDAEEI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  970 RSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQgTSRSLRLIQDRVAEVQQVL--RPAEKLVTSMTKQLGDFWTRMEELR 1047
Cdd:cd00176    78 QERLEELNQRWEELRELAEERRQRLEEALDLQQ-FFRDADDLEQWLEEKEAALasEDLGKDLESVEELLKKHKELEEELE 156
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 530366188 1048 -HQARQQGAEAvQAQQLAEGASEQALSA-QEGFERIKQKYAELKDRL 1092
Cdd:cd00176   157 aHEPRLKSLNE-LAEELLEEGHPDADEEiEEKLEELNERWEELLELA 202
TolC COG1538
Outer membrane protein TolC [Cell wall/membrane/envelope biogenesis];
831-1098 3.61e-04

Outer membrane protein TolC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441147 [Multi-domain]  Cd Length: 367  Bit Score: 44.26  E-value: 3.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  831 MAGQVAE---QLRGFNAQLQRTRQMIRAAEESASQIQssaQRLETQVSAsrsqmEEDVRRTRLLIQQVRDFLTDpdtdAA 907
Cdd:COG1538    74 LAAEVAQayfDLLAAQEQLALAEENLALAEELLELAR---ARYEAGLAS-----RLDVLQAEAQLAQARAQLAQ----AE 141
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  908 TIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQ---DIARARRLQAEAEEARSRAHA--------- 975
Cdd:COG1538   142 AQLAQARNALALLLGLPPPAPLDLPDPLPPLPPLPPSLPGLPSEALErrpDLRAAEAQLEAAEAEIGVARAaflpslsls 221
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  976 ----VEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLiqdRVAEVQQvlrpaEKLVTSMTKQLgdfwtrmEELRHQAR 1051
Cdd:COG1538   222 asygYSSSDDLFSGGSDTWSVGLSLSLPLFDGGRNRARV---RAAKAQL-----EQAEAQYEQTV-------LQALQEVE 286
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 530366188 1052 QQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYaelkdRLGQSSML 1098
Cdd:COG1538   287 DALAALRAAREQLEALEEALEAAEEALELARARY-----RAGLASLL 328
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
946-1122 3.81e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 3.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  946 DLVLSQTKQDIARarrLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSL----RLIQDRVAEVQQV 1021
Cdd:COG3883    15 DPQIQAKQKELSE---LQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIaeaeAEIEERREELGER 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1022 LR----------PAEKLVTSmtKQLGDFWTRMEELRHQARQQGA---EAVQAQQLAEGASEQALSAQEGFERIKQKYAEL 1088
Cdd:COG3883    92 ARalyrsggsvsYLDVLLGS--ESFSDFLDRLSALSKIADADADlleELKADKAELEAKKAELEAKLAELEALKAELEAA 169
                         170       180       190
                  ....*....|....*....|....*....|....
gi 530366188 1089 KDRLGQSsmLGEQGARIQSVKTEAEELFGETMEM 1122
Cdd:COG3883   170 KAELEAQ--QAEQEALLAQLSAEEAAAEAQLAEL 201
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
626-980 3.89e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 3.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  626 DAKSKIEQIRAVLSSPAVTEQEVAQVASAILsLRRTLQGLQLDlpleEETLSLPRDLESLDRSFNGLLTMYQRKREQFEK 705
Cdd:COG3206    65 SSDVLLSGLSSLSASDSPLETQIEILKSRPV-LERVVDKLNLD----EDPLGEEASREAAIERLRKNLTVEPVKGSNVIE 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  706 IS--SADPSGAFRM---LSTAYEQSaQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGgggtgspKLVALRLEmsslpdl 780
Cdd:COG3206   140 ISytSPDPELAAAVanaLAEAYLEQ-NLELRREEARKALEFLEEQLPELRKELEEAEA-------ALEEFRQK------- 204
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  781 tptfNKLcgnsrqmactpISCPGElcpqdngtacgsrcrgvlpraggaflmAGQVAEQLRGFNAQLQRTRQMIRAAEESA 860
Cdd:COG3206   205 ----NGL-----------VDLSEE---------------------------AKLLLQQLSELESQLAEARAELAEAEARL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  861 SQIQS----------------SAQRLETQVSASRSQMEE----------DVRRTRLLIQQVRDFLtdpDTDAATIQEVSE 914
Cdd:COG3206   243 AALRAqlgsgpdalpellqspVIQQLRAQLAELEAELAElsarytpnhpDVIALRAQIAALRAQL---QQEAQRILASLE 319
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  915 AVLALwLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARR----LQAEAEEARSRAHAVEGQV 980
Cdd:COG3206   320 AELEA-LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARElyesLLQRLEEARLAEALTVGNV 388
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
837-1127 4.82e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 43.75  E-value: 4.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  837 EQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQvsasRSQMEEDVRRTRL----LIQQVRDFLtdpdtdaATIQEV 912
Cdd:COG1340    29 EKRDELNEELKELAEKRDELNAQVKELREEAQELREK----RDELNEKVKELKEerdeLNEKLNELR-------EELDEL 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  913 SEAVLALWLPTDSATVLQKmnEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARsRAHAVEGQVEDVVGNLRQgtv 992
Cdd:COG1340    98 RKELAELNKAGGSIDKLRK--EIERLEWRQQTEVLSPEEEKELVEKIKELEKELEKAK-KALEKNEKLKELRAELKE--- 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  993 aLQEAQDTmqgtsrslrlIQDRVAE-VQQvlrpAEKLVTSMTKQLGdfwtRMEELRHQARQQGAEAVQAQQLAEGASEQa 1071
Cdd:COG1340   172 -LRKEAEE----------IHKKIKElAEE----AQELHEEMIELYK----EADELRKEADELHKEIVEAQEKADELHEE- 231
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530366188 1072 lsaqegFERIKQKYAELKDRLgqsSMLGEQGARIQSVKTEaEELFGETMEMMDRMK 1127
Cdd:COG1340   232 ------IIELQKELRELRKEL---KKLRKKQRALKREKEK-EELEEKAEEIFEKLK 277
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
954-1092 6.10e-04

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 41.87  E-value: 6.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   954 QDIARAR-RLQAEAEEARSR----AHAVEGQVEDVVGNLRQGTVALqeAQDTMQGTSRSLRLIQDRVAEVQQVLRpaEKL 1028
Cdd:pfam01442   33 KETEALReRLQKDLEEVRAKlepyLEELQAKLGQNVEELRQRLEPY--TEELRKRLNADAEELQEKLAPYGEELR--ERL 108
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530366188  1029 VTSMTKQLGDFWTRMEELRHQARQQgaeavqAQQLAEGASEQALSAQEgfeRIKQKYAELKDRL 1092
Cdd:pfam01442  109 EQNVDALRARLAPYAEELRQKLAER------LEELKESLAPYAEEVQA---QLSQRLQELREKL 163
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
940-1095 6.90e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 43.11  E-value: 6.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  940 ARLPNVDLvlsQTKQDIARARRLQAEAEEARSRA-HAVEGQVEDVVGNLRQGTVALQEAQDTMQgtsRSLRLIQDRVAEV 1018
Cdd:COG1566    74 ARLDPTDL---QAALAQAEAQLAAAEAQLARLEAeLGAEAEIAAAEAQLAAAQAQLDLAQRELE---RYQALYKKGAVSQ 147
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530366188 1019 QQVLRpAEklvtsmtkqlgdfwTRMEELRHQARQQGAEAVQAQQLAEGASEQAlSAQEGFERIKQKYAELKDRLGQS 1095
Cdd:COG1566   148 QELDE-AR--------------AALDAAQAQLEAAQAQLAQAQAGLREEEELA-AAQAQVAQAEAALAQAELNLART 208
TolA COG3064
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];
834-1139 1.12e-03

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442298 [Multi-domain]  Cd Length: 485  Bit Score: 43.10  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  834 QVAEQLRGFNAQLQRTRQMIRAAEESASQ--IQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDfLTDPDTDAATIQE 911
Cdd:COG3064    13 AAQERLEQAEAEKRAAAEAEQKAKEEAEEerLAELEAKRQAEEEAREAKAEAEQRAAELAAEAAKK-LAEAEKAAAEAEK 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  912 VSEAvlalwlptDSATVLQKmNEIQAIAARLPNVdlvlsQTKQDIARARR-----LQAEAEEARSRAHA---VEGQVEDV 983
Cdd:COG3064    92 KAAA--------EKAKAAKE-AEAAAAAEKAAAA-----AEKEKAEEAKRkaeeeAKRKAEEERKAAEAeaaAKAEAEAA 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  984 VGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWtRMEELRHQARQQGAEAVQAQQL 1063
Cdd:COG3064   158 RAAAAAAAAAAAAAARAAAGAAAALVAAAAAAVEAADTAAAAAAALAAAAAAAAADA-ALLALAVAARAAAASREAALAA 236
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530366188 1064 AEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQA 1139
Cdd:COG3064   237 VEATEEAALGGAEEAADLAAVGVLGAALAAAAAGAAALSSGLVVVAAALAGLAAAAAGLVLDDSAALAAELLGAVA 312
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
825-1069 1.16e-03

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 43.09  E-value: 1.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  825 AGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDT 904
Cdd:COG0840   107 AALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAA 186
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  905 DAATIQEVSeAVLALWLptdSATVLQKMNEIQAIAARLPNVDL--VLSQTKQD----IARA------------RRLQAEA 966
Cdd:COG0840   187 ALLALVALA-IILALLL---SRSITRPLRELLEVLERIAEGDLtvRIDVDSKDeigqLADAfnrmienlrelvGQVRESA 262
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  967 EEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEEL 1046
Cdd:COG0840   263 EQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGEVVEEAVEGIEEI 342
                         250       260
                  ....*....|....*....|...
gi 530366188 1047 RHQArQQGAEAVqaQQLAEGASE 1069
Cdd:COG0840   343 RESV-EETAETI--EELGESSQE 362
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
827-1155 1.39e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.90  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   827 GAFLMAG-----QVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLtd 901
Cdd:pfam12128  332 GAFLDADietaaADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQ-- 409
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   902 pdtdAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQ---TKQDIARARRLQAEAEEARSRAHAVEG 978
Cdd:pfam12128  410 ----LAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQataTPELLLQLENFDERIERAREEQEAANA 485
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188   979 QVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRP-AEKLVTSMTKQLGDF------------------ 1039
Cdd:pfam12128  486 EVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPqAGTLLHFLRKEAPDWeqsigkvispellhrtdl 565
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  1040 -----------------------------WTRMEELRHQARQQGAEAVQAQQLAEGASEQALS--------AQEGFERIK 1082
Cdd:pfam12128  566 dpevwdgsvggelnlygvkldlkridvpeWAASEEELRERLDKAEEALQSAREKQAAAEEQLVqangelekASREETFAR 645
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530366188  1083 QKYAELKDRLGQSSMLGEQGAR-IQSVKTEAEELFGETMEMMDRmkdmELELLRGSQAIMLRSADLTGLEKRVE 1155
Cdd:pfam12128  646 TALKNARLDLRRLFDEKQSEKDkKNKALAERKDSANERLNSLEA----QLKQLDKKHQAWLEEQKEQKREARTE 715
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
832-1092 1.79e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.63  E-value: 1.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  832 AGQVAEQLRGFNAQLQRT---RQMIRAAEESASQIQS---SAQRLETQVSASRSQMEEDVRRTRLLIQQVRDfltdpdTD 905
Cdd:COG3096   395 KSQLADYQQALDVQQTRAiqyQQAVQALEKARALCGLpdlTPENAEDYLAAFRAKEQQATEEVLELEQKLSV------AD 468
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  906 AATIQ--EVSEAVLALWLPTDSATVLQKMNEI-------QAIAARLPNVDLVLSQTKQDIAR---ARRLQAEAEEARSRA 973
Cdd:COG3096   469 AARRQfeKAYELVCKIAGEVERSQAWQTARELlrryrsqQALAQRLQQLRAQLAELEQRLRQqqnAERLLEEFCQRIGQQ 548
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  974 HAVEGQVEDVvgnlrqgtvaLQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQ 1053
Cdd:COG3096   549 LDAAEELEEL----------LAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQS 618
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 530366188 1054 GAEAVQAQQLAEgASEQALSAQEGFERIKQKYAELKDRL 1092
Cdd:COG3096   619 GEALADSQEVTA-AMQQLLEREREATVERDELAARKQAL 656
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
936-1162 2.01e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 2.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  936 QAIAAR-LPNVD-----LVL--SQTKQDIARA-------RRLQAEAEEARSRAHAVEgQVEDVVGNLRQGTVALQEAQDT 1000
Cdd:COG4913   199 KTQSFKpIGDLDdfvreYMLeePDTFEAADALvehfddlERAHEALEDAREQIELLE-PIRELAERYAAARERLAELEYL 277
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1001 MQGT-----SRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAqqlAEGASEQALSAQ 1075
Cdd:COG4913   278 RAALrlwfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ---LEREIERLEREL 354
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1076 EGFERIKQKYAELKDRLGQSSMLGEQG-----ARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAImlrSADLTGL 1150
Cdd:COG4913   355 EERERRRARLEALLAALGLPLPASAEEfaalrAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL---EAEIASL 431
                         250
                  ....*....|....*....
gi 530366188 1151 EKR-------VEQIRDHIN 1162
Cdd:COG4913   432 ERRksniparLLALRDALA 450
cc_LAMB2_C cd22299
C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2); LAMB2 is also called ...
1102-1172 2.90e-03

C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2); LAMB2 is also called laminin B1s chain, laminin-11 subunit beta, laminin-14 subunit beta, laminin-15 subunit beta, laminin-3 subunit beta, laminin-4 subunit beta, laminin-7 subunit beta, laminin-9 subunit beta, S-laminin subunit beta, or S-LAM beta (LAMS). It is an important component of the interphotoreceptor matrix and plays a role in rod morphogenesis. It may also have an important function in the sarcolemmal basement membrane. Mutations of the LAMB2 gene mainly cause Pierson syndrome (microcoria-congenital nephrosis syndrome). LAMB2 is a component of laminin, a complex glycoprotein consisting of three different polypeptide chains (alpha, beta, gamma). Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. This model corresponds to the C-terminal coiled-coil domain of LAMB2, which may be involved in the integrin binding activity.


Pssm-ID: 411970 [Multi-domain]  Cd Length: 72  Bit Score: 37.42  E-value: 2.90e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530366188 1102 GARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
Cdd:cd22299     2 KGKAEQLRDEAKGLLQDAQDKLQRLQDLEVQYEENEKVLEGKARQLDGLEDKMKEILKAINQQIQIYNTCQ 72
PRK06975 PRK06975
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
825-964 3.28e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 41.63  E-value: 3.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  825 AGGAFL------MAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSqmeedvrRTRLLIQQVRDF 898
Cdd:PRK06975  339 VGGYALnrkvdrLDQELVQRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDGKLADAQS-------AQQALEQQYQDL 411
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530366188  899 LTdpDTDAATIQEV----SEAVLALWLPTDSATVLQKMneiQAIAARL-----PNVDLVLSQTKQDIARARRLQA 964
Cdd:PRK06975  412 SR--NRDDWMIAEVeqmlSSASQQLQLTGNVQLALIAL---QNADARLatsdsPQAVAVRKAIAQDIERLKAAPS 481
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
828-1020 5.03e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 41.32  E-value: 5.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  828 AFLMAGQVAEQLRGF-------NAQLQRTRQMIraaEESASQIQSS-AQRLETQVSASRSQMEEDVRRTRLliqqvRDFL 899
Cdd:PRK10246  281 AALSLAQPARQLRPHweriqeqSAALAHTRQQI---EEVNTRLQSTmALRARIRHHAAKQSAELQAQQQSL-----NTWL 352
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  900 TDPDTDAATIQEVS--EAVLAlWLPTDSATVLQKMNEIQAIAARLPNV-DLVLSQTKQDIARARRLQAEAEEARSRAHAV 976
Cdd:PRK10246  353 AEHDRFRQWNNELAgwRAQFS-QQTSDREQLRQWQQQLTHAEQKLNALpAITLTLTADEVAAALAQHAEQRPLRQRLVAL 431
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 530366188  977 EGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ 1020
Cdd:PRK10246  432 HGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQ 475
growth_prot_Scy NF041483
polarized growth protein Scy;
833-1126 5.46e-03

polarized growth protein Scy;


Pssm-ID: 469371 [Multi-domain]  Cd Length: 1293  Bit Score: 40.96  E-value: 5.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  833 GQVAEQ-LRgfNAQLQrTRQMIRAAEESASQIQSSAQRL--ETQVSASRSQME---EDVRRTRLLIQQVRDfltdpdtDA 906
Cdd:NF041483   71 GYQAEQlLR--NAQIQ-ADQLRADAERELRDARAQTQRIlqEHAEHQARLQAElhtEAVQRRQQLDQELAE-------RR 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  907 ATIQ-EVSEAVLalWlptdsATVLQKMNEIQAiaARLpnVDLVLSQTKQDIARAR------------RLQAEAEEARSRA 973
Cdd:NF041483  141 QTVEsHVNENVA--W-----AEQLRARTESQA--RRL--LDESRAEAEQALAAARaeaerlaeearqRLGSEAESARAEA 209
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  974 HAVEGQV-EDVVGNLRQGTVALQEAqdtmqgTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQ 1052
Cdd:NF041483  210 EAILRRArKDAERLLNAASTQAQEA------TDHAEQLRSSTAAESDQARRQAAELSRAAEQRMQEAEEALREARAEAEK 283
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530366188 1053 QGAEAVQ--AQQL--AEGASEQalsaqegfeRIKQKYAELkdrlgqSSMLGEQGARIQSVKTEAEELFGETMEMMDRM 1126
Cdd:NF041483  284 VVAEAKEaaAKQLasAESANEQ---------RTRTAKEEI------ARLVGEATKEAEALKAEAEQALADARAEAEKL 346
mukB PRK04863
chromosome partition protein MukB;
843-1155 7.58e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 40.71  E-value: 7.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  843 NAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMeedvrrtrLLIQQVRDF--LTDPDTDAATIQEVSEAVLALw 920
Cdd:PRK04863  836 EAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGL--------SALNRLLPRlnLLADETLADRVEEIREQLDEA- 906
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  921 lptdsatvLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQV---EDVVGnlRQGTVALQEA 997
Cdd:PRK04863  907 --------EEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAfalTEVVQ--RRAHFSYEDA 976
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  998 QDTMQGTSRSLRLIQDRVAEVQQVLRpaeklvtsmtkqlgdfwtrmeELRHQARQQGAEAVQAQQLAegaseqaLSAQEG 1077
Cdd:PRK04863  977 AEMLAKNSDLNEKLRQRLEQAEQERT---------------------RAREQLRQAQAQLAQYNQVL-------ASLKSS 1028
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530366188 1078 FERIKQKYAELKDRLGQSSMLGEQGARIQSvKTEAEELFGETMEmmDRMKDMELELLRGSQaimlrSADLTGLEKRVE 1155
Cdd:PRK04863 1029 YDAKRQMLQELKQELQDLGVPADSGAEERA-RARRDELHARLSA--NRSRRNQLEKQLTFC-----EAEMDNLTKKLR 1098
TolC COG1538
Outer membrane protein TolC [Cell wall/membrane/envelope biogenesis];
936-1074 8.07e-03

Outer membrane protein TolC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441147 [Multi-domain]  Cd Length: 367  Bit Score: 40.02  E-value: 8.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188  936 QAIAARLPNVDLVLSQtkqdiARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQdtmqgtsRSLRLIQDRV 1015
Cdd:COG1538    32 QARAGLLPSQELDLGG-----KRRARIEAAKAQAEAAEADLRAARLDLAAEVAQAYFDLLAAQ-------EQLALAEENL 99
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530366188 1016 AEVQQVLRPAEKLVtsmtkQLGDfWTRMEELRHQARQQGAEA-VQAQQLAEGASEQALSA 1074
Cdd:COG1538   100 ALAEELLELARARY-----EAGL-ASRLDVLQAEAQLAQARAqLAQAEAQLAQARNALAL 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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