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Conserved domains on  [gi|530397536|ref|XP_005274424|]
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centrosomal protein of 295 kDa isoform X6 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PTZ00121 super family cl31754
MAEBL; Provisional
27-554 6.44e-08

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 6.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   27 ERRRKLRLLQVREQERDIALQIREDI---KQRRNQQFTRLAEELRAEWEESQTQKIQNLEKLYLAS--LRSMGEGHRQAK 101
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAikaEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAeeAKKADEAKKKAE 1325
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  102 ENEPDLDALAQRAAERKRKADLRHKEALKVQKNQKEillkqktwhIKARKEALLVEKERSAKITSLPPPPPTlfeniEVK 181
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA---------AEEKAEAAEKKKEEAKKKADAAKKKAE-----EKK 1391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  182 RISAVKTNSstyhhlhtfvnrETDTKRPDARLAAEEEAKRLEELQKQA-----AQERMERFEKAHvRGFQAMKKIHLAQN 256
Cdd:PTZ00121 1392 KADEAKKKA------------EEDKKKADELKKAAAAKKKADEAKKKAeekkkADEAKKKAEEAK-KADEAKKKAEEAKK 1458
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  257 QEKLMKELKQLQQEDLARRRQTVAQMPPQLvelpYKRSEMKEDWQRELEFAFEDMYNADRKVKGNlilhlepeplptvtn 336
Cdd:PTZ00121 1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEA----KKKAEEAKKKADEAKKAAEAKKKADEAKKAE--------------- 1519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  337 qiQDEELDLSMEQENLGAAEDLPVTEAEICSSEtdvplVMKTQQIPSKVLFKKLLNKIRSQKSlwtiKSMSEDESEMITT 416
Cdd:PTZ00121 1520 --EAKKADEAKKAEEAKKADEAKKAEEKKKADE-----LKKAEELKKAEEKKKAEEAKKAEED----KNMALRKAEEAKK 1588
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  417 VSEieskAPTVESGTIASKERTLSSGQEQVVESDTLTIESGPLASEDKPLSCGTNSGKEQEINETLPITTVAQSSVLLHP 496
Cdd:PTZ00121 1589 AEE----ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA 1664
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 530397536  497 QEAAARIRMSARQKQIMEIEEQKQKQLELLEQIEQQKLRLETdcFRAQLEEEKRKKTQ 554
Cdd:PTZ00121 1665 EEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE--LKKKEAEEKKKAEE 1720
ALMS_motif super family cl21154
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
2491-2612 3.07e-07

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


The actual alignment was detected with superfamily member pfam15309:

Pssm-ID: 464634  Cd Length: 131  Bit Score: 51.61  E-value: 3.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  2491 SLQEAFIKRKKSFMERSHQRQKeiRNKIHVSE-------NSQIKTVKEKPSISSSVSRLKGVNKVRASFPEDRKTTQALR 2563
Cdd:pfam15309    5 SLQEALEMHRPDFISRSRERLK--RLELLVEErklqevlQRERERLFNKPIPRTNKRQQTVPLPDNLFKPRRRAISKKEM 82
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 530397536  2564 HQRGLRLYNQLAEVKQQKEEKTKQEAYAQNRARAKEFHKKTLEKLRAKN 2612
Cdd:pfam15309   83 IARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKKKVTNRVLGRK 131
 
Name Accession Description Interval E-value
PTZ00121 PTZ00121
MAEBL; Provisional
27-554 6.44e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 6.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   27 ERRRKLRLLQVREQERDIALQIREDI---KQRRNQQFTRLAEELRAEWEESQTQKIQNLEKLYLAS--LRSMGEGHRQAK 101
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAikaEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAeeAKKADEAKKKAE 1325
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  102 ENEPDLDALAQRAAERKRKADLRHKEALKVQKNQKEillkqktwhIKARKEALLVEKERSAKITSLPPPPPTlfeniEVK 181
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA---------AEEKAEAAEKKKEEAKKKADAAKKKAE-----EKK 1391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  182 RISAVKTNSstyhhlhtfvnrETDTKRPDARLAAEEEAKRLEELQKQA-----AQERMERFEKAHvRGFQAMKKIHLAQN 256
Cdd:PTZ00121 1392 KADEAKKKA------------EEDKKKADELKKAAAAKKKADEAKKKAeekkkADEAKKKAEEAK-KADEAKKKAEEAKK 1458
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  257 QEKLMKELKQLQQEDLARRRQTVAQMPPQLvelpYKRSEMKEDWQRELEFAFEDMYNADRKVKGNlilhlepeplptvtn 336
Cdd:PTZ00121 1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEA----KKKAEEAKKKADEAKKAAEAKKKADEAKKAE--------------- 1519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  337 qiQDEELDLSMEQENLGAAEDLPVTEAEICSSEtdvplVMKTQQIPSKVLFKKLLNKIRSQKSlwtiKSMSEDESEMITT 416
Cdd:PTZ00121 1520 --EAKKADEAKKAEEAKKADEAKKAEEKKKADE-----LKKAEELKKAEEKKKAEEAKKAEED----KNMALRKAEEAKK 1588
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  417 VSEieskAPTVESGTIASKERTLSSGQEQVVESDTLTIESGPLASEDKPLSCGTNSGKEQEINETLPITTVAQSSVLLHP 496
Cdd:PTZ00121 1589 AEE----ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA 1664
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 530397536  497 QEAAARIRMSARQKQIMEIEEQKQKQLELLEQIEQQKLRLETdcFRAQLEEEKRKKTQ 554
Cdd:PTZ00121 1665 EEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE--LKKKEAEEKKKAEE 1720
ALMS_motif pfam15309
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
2491-2612 3.07e-07

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


Pssm-ID: 464634  Cd Length: 131  Bit Score: 51.61  E-value: 3.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  2491 SLQEAFIKRKKSFMERSHQRQKeiRNKIHVSE-------NSQIKTVKEKPSISSSVSRLKGVNKVRASFPEDRKTTQALR 2563
Cdd:pfam15309    5 SLQEALEMHRPDFISRSRERLK--RLELLVEErklqevlQRERERLFNKPIPRTNKRQQTVPLPDNLFKPRRRAISKKEM 82
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 530397536  2564 HQRGLRLYNQLAEVKQQKEEKTKQEAYAQNRARAKEFHKKTLEKLRAKN 2612
Cdd:pfam15309   83 IARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKKKVTNRVLGRK 131
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
27-164 7.64e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 7.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536    27 ERRRKLRLLQVREQERDIAL----------QIREDIKQRRNQQFTRLAEELRAEWEESQTQKIQNLEKlylASLRSMGEG 96
Cdd:pfam17380  375 SRMRELERLQMERQQKNERVrqeleaarkvKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEE---ERAREMERV 451
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536    97 HRQAKENEPDLDALAQRAAERKRKADLRHKEALKVQ--KNQKEILLKQKtwhIKARKEALLvEKERSAKI 164
Cdd:pfam17380  452 RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKraEEQRRKILEKE---LEERKQAMI-EEERKRKL 517
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
22-278 1.36e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.62  E-value: 1.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   22 LKEDYERRRKLRLLQVREQERDIALQIRE-DIKQRRNQQFTRLAEELRAEWEESQTQ-------------KIQNLEKLYL 87
Cdd:COG1196   205 LERQAEKAERYRELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAElaeleaeleelrlELEELELELE 284
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   88 ASLRSMGEGHRQAKENEPDLDALAQRAAERKRKADLRHKEALkvQKNQKEILLKQKTwhIKARKEALLVEKERSAKITSL 167
Cdd:COG1196   285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA--ELEEELEELEEEL--EELEEELEEAEEELEEAEAEL 360
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  168 PPPPPTLfENIEVKRISAVKTNSSTYHHLHTFVNRETDTKRPDARLAAEEEA--KRLEELQKQAAQERMERFEKAHVRGF 245
Cdd:COG1196   361 AEAEEAL-LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAllERLERLEEELEELEEALAELEEEEEE 439
                         250       260       270
                  ....*....|....*....|....*....|...
gi 530397536  246 QAMKKIHLAQNQEKLMKELKQLQQEDLARRRQT 278
Cdd:COG1196   440 EEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
 
Name Accession Description Interval E-value
PTZ00121 PTZ00121
MAEBL; Provisional
27-554 6.44e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 6.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   27 ERRRKLRLLQVREQERDIALQIREDI---KQRRNQQFTRLAEELRAEWEESQTQKIQNLEKLYLAS--LRSMGEGHRQAK 101
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAikaEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAeeAKKADEAKKKAE 1325
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  102 ENEPDLDALAQRAAERKRKADLRHKEALKVQKNQKEillkqktwhIKARKEALLVEKERSAKITSLPPPPPTlfeniEVK 181
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA---------AEEKAEAAEKKKEEAKKKADAAKKKAE-----EKK 1391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  182 RISAVKTNSstyhhlhtfvnrETDTKRPDARLAAEEEAKRLEELQKQA-----AQERMERFEKAHvRGFQAMKKIHLAQN 256
Cdd:PTZ00121 1392 KADEAKKKA------------EEDKKKADELKKAAAAKKKADEAKKKAeekkkADEAKKKAEEAK-KADEAKKKAEEAKK 1458
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  257 QEKLMKELKQLQQEDLARRRQTVAQMPPQLvelpYKRSEMKEDWQRELEFAFEDMYNADRKVKGNlilhlepeplptvtn 336
Cdd:PTZ00121 1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEA----KKKAEEAKKKADEAKKAAEAKKKADEAKKAE--------------- 1519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  337 qiQDEELDLSMEQENLGAAEDLPVTEAEICSSEtdvplVMKTQQIPSKVLFKKLLNKIRSQKSlwtiKSMSEDESEMITT 416
Cdd:PTZ00121 1520 --EAKKADEAKKAEEAKKADEAKKAEEKKKADE-----LKKAEELKKAEEKKKAEEAKKAEED----KNMALRKAEEAKK 1588
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  417 VSEieskAPTVESGTIASKERTLSSGQEQVVESDTLTIESGPLASEDKPLSCGTNSGKEQEINETLPITTVAQSSVLLHP 496
Cdd:PTZ00121 1589 AEE----ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA 1664
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 530397536  497 QEAAARIRMSARQKQIMEIEEQKQKQLELLEQIEQQKLRLETdcFRAQLEEEKRKKTQ 554
Cdd:PTZ00121 1665 EEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE--LKKKEAEEKKKAEE 1720
ALMS_motif pfam15309
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
2491-2612 3.07e-07

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


Pssm-ID: 464634  Cd Length: 131  Bit Score: 51.61  E-value: 3.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  2491 SLQEAFIKRKKSFMERSHQRQKeiRNKIHVSE-------NSQIKTVKEKPSISSSVSRLKGVNKVRASFPEDRKTTQALR 2563
Cdd:pfam15309    5 SLQEALEMHRPDFISRSRERLK--RLELLVEErklqevlQRERERLFNKPIPRTNKRQQTVPLPDNLFKPRRRAISKKEM 82
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 530397536  2564 HQRGLRLYNQLAEVKQQKEEKTKQEAYAQNRARAKEFHKKTLEKLRAKN 2612
Cdd:pfam15309   83 IARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKKKVTNRVLGRK 131
PTZ00121 PTZ00121
MAEBL; Provisional
23-317 2.27e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 2.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   23 KEDYERRRKLRLLQVREQERDIALQIREDIKQ---------RRNQQFTRLAEELRAEWEE------------SQTQKIQN 81
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEEnkikaaeeaKKAEEDKKKAEEAKKAEEDekkaaealkkeaEEAKKAEE 1706
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   82 LEKLYLASLRSMGEGHRQAKENEPDLDALAQRAAERKRKA-DLRHKEALKVQKNQKEILLKQKTWHIKARKEALL---VE 157
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAeEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIeeeLD 1786
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  158 KERSAKITSLPPPPPTLFENIEVKRISAVKTNSSTYHHLHTFVNRETDTKrpDARLAAEEEAKrleELQKQAAQERMERF 237
Cdd:PTZ00121 1787 EEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVA--DSKNMQLEEAD---AFEKHKFNKNNENG 1861
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  238 EKAHVRGFQAMKKIHLAQNQEKLM--KELKQLQQEDLARRRQTvAQMPPQLVELPYKRSEMKEDWQRELEFAFEDMYNAD 315
Cdd:PTZ00121 1862 EDGNKEADFNKEKDLKEDDEEEIEeaDEIEKIDKDDIEREIPN-NNMAGKNNDIIDDKLDKDEYIKRDAEETREEIIKIS 1940

                  ..
gi 530397536  316 RK 317
Cdd:PTZ00121 1941 KK 1942
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
27-164 7.64e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 7.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536    27 ERRRKLRLLQVREQERDIAL----------QIREDIKQRRNQQFTRLAEELRAEWEESQTQKIQNLEKlylASLRSMGEG 96
Cdd:pfam17380  375 SRMRELERLQMERQQKNERVrqeleaarkvKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEE---ERAREMERV 451
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536    97 HRQAKENEPDLDALAQRAAERKRKADLRHKEALKVQ--KNQKEILLKQKtwhIKARKEALLvEKERSAKI 164
Cdd:pfam17380  452 RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKraEEQRRKILEKE---LEERKQAMI-EEERKRKL 517
PTZ00121 PTZ00121
MAEBL; Provisional
12-277 8.83e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 8.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   12 RLSPNEEAFILKEDYERRRKLRLLQVREQERDIALQIREDIKQRRNQQFTRLAEELRaeweesqtQKIQNLEKLYLASLR 91
Cdd:PTZ00121 1576 KNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK--------KKVEQLKKKEAEEKK 1647
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   92 SMGEGHRQAKENEPDLDALAQRAAERKRKADlrhkEALKVQKNQKEillkqktwhikaRKEALLVEKERSAKITSLPPPp 171
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAE----EAKKAEEDEKK------------AAEALKKEAEEAKKAEELKKK- 1710
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  172 ptlfENIEVKRISAVKTNSstyhhlhtfvnRETDTKRPDARLAAEEEAKRLEELQKqaaqERMERFEKAHVRGFQAMKKI 251
Cdd:PTZ00121 1711 ----EAEEKKKAEELKKAE-----------EENKIKAEEAKKEAEEDKKKAEEAKK----DEEEKKKIAHLKKEEEKKAE 1771
                         250       260
                  ....*....|....*....|....*.
gi 530397536  252 HLAQNQEKLMKElkQLQQEDLARRRQ 277
Cdd:PTZ00121 1772 EIRKEKEAVIEE--ELDEEDEKRRME 1795
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
22-278 1.36e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.62  E-value: 1.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   22 LKEDYERRRKLRLLQVREQERDIALQIRE-DIKQRRNQQFTRLAEELRAEWEESQTQ-------------KIQNLEKLYL 87
Cdd:COG1196   205 LERQAEKAERYRELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAElaeleaeleelrlELEELELELE 284
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   88 ASLRSMGEGHRQAKENEPDLDALAQRAAERKRKADLRHKEALkvQKNQKEILLKQKTwhIKARKEALLVEKERSAKITSL 167
Cdd:COG1196   285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA--ELEEELEELEEEL--EELEEELEEAEEELEEAEAEL 360
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  168 PPPPPTLfENIEVKRISAVKTNSSTYHHLHTFVNRETDTKRPDARLAAEEEA--KRLEELQKQAAQERMERFEKAHVRGF 245
Cdd:COG1196   361 AEAEEAL-LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAllERLERLEEELEELEEALAELEEEEEE 439
                         250       260       270
                  ....*....|....*....|....*....|...
gi 530397536  246 QAMKKIHLAQNQEKLMKELKQLQQEDLARRRQT 278
Cdd:COG1196   440 EEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
38-281 7.28e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 7.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536    38 REQERDIALQIREDIKQRRNQQFTRLaeELRAEWEESQTQKIQNLEKlylaSLRSMGEGHRQAKENEPDLDALAQ----R 113
Cdd:pfam17380  287 RQQQEKFEKMEQERLRQEKEEKAREV--ERRRKLEEAEKARQAEMDR----QAAIYAEQERMAMERERELERIRQeerkR 360
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   114 AAERKRKADL-------RHKEALKVQKNQKEILLKQKtwhIKARKEALLVEKERSAKITSlppppptlfENIEVKRISAV 186
Cdd:pfam17380  361 ELERIRQEEIameisrmRELERLQMERQQKNERVRQE---LEAARKVKILEEERQRKIQQ---------QKVEMEQIRAE 428
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   187 KTNSstyhhlhtfvnRETDTKRPDARLAAEEEAKRLEELQKQAAQERMERFEKAHVRGFQAMKKihlAQNQEKLMKELKQ 266
Cdd:pfam17380  429 QEEA-----------RQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEK---EKRDRKRAEEQRR 494
                          250
                   ....*....|....*..
gi 530397536   267 --LQQEDLARRRQTVAQ 281
Cdd:pfam17380  495 kiLEKELEERKQAMIEE 511
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
17-276 1.95e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 1.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   17 EEAFILKEDYERRRKLRLLQVREQERDIA---LQIREDIKQRRNQQFTRLAEELRAEWEESQTQK-IQNLEKLYLASLRS 92
Cdd:COG1196   343 EEELEEAEEELEEAEAELAEAEEALLEAEaelAEAEEELEELAEELLEALRAAAELAAQLEELEEaEEALLERLERLEEE 422
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   93 MGEGHRQAKENEPDLDALAQRAAERKRKADLRHKEALKVQKNQKEILLKQKTWHIKARKEALLVEKERSAKITSLPPPPP 172
Cdd:COG1196   423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  173 TLFENIEVKRISAVKTNSSTYHHLHtfVNRETDTKRPDARLAA------------EEEAKRLEELQKQAAQERMERFEKA 240
Cdd:COG1196   503 YEGFLEGVKAALLLAGLRGLAGAVA--VLIGVEAAYEAALEAAlaaalqnivvedDEVAAAAIEYLKAAKAGRATFLPLD 580
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 530397536  241 HVRGFQAMKKIHLAQNQEKLMKELKQLQQEDLARRR 276
Cdd:COG1196   581 KIRARAALAAALARGAIGAAVDLVASDLREADARYY 616
PRK12704 PRK12704
phosphodiesterase; Provisional
3-141 2.14e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 2.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536    3 RKVVNTHKLRLSPNEEAFILKE---DYERRRKLRLLQVREQERDIALQIREDIKQRRNqQFTRLAEELRAEwEESQTQKI 79
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRILEEakkEAEAIKKEALLEAKEEIHKLRNEFEKELRERRN-ELQKLEKRLLQK-EENLDRKL 102
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530397536   80 QNLEKlylaslrsmgeghrqaKENEpdLDALAQRAAERKRKADLRHKEALKVQKNQKEILLK 141
Cdd:PRK12704  103 ELLEK----------------REEE--LEKKEKELEQKQQELEKKEEELEELIEEQLQELER 146
PTZ00121 PTZ00121
MAEBL; Provisional
22-307 3.35e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 3.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   22 LKEDYERRRKLRLLQVR-EQERDIALQIREDIKQRRNQQFTRLAEELRAEWEESQTQKIQNLEKLYLASLRSMGEGHRQA 100
Cdd:PTZ00121 1307 AKKKAEEAKKADEAKKKaEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK 1386
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  101 KENEPDLDALAQRAAERKRKAD-LRHKEALKVQKNQKEILLKQKTWHIKARKEAllvEKERSAKITSLPPPPPTLFENIE 179
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEEDKKKADeLKKAAAAKKKADEAKKKAEEKKKADEAKKKA---EEAKKADEAKKKAEEAKKAEEAK 1463
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  180 VKRISAVKTNSSTYhhlhtfvNRETDTKRPDARLAAEEEAKRLEELQKQA-AQERMERFEKA-HVRGFQAMKKIHLAQNQ 257
Cdd:PTZ00121 1464 KKAEEAKKADEAKK-------KAEEAKKADEAKKKAEEAKKKADEAKKAAeAKKKADEAKKAeEAKKADEAKKAEEAKKA 1536
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 530397536  258 EKLMKELKQLQQEDLARRRQTVAQMPPQLVELPYKRSEMKEDWQRELEFA 307
Cdd:PTZ00121 1537 DEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586
PTZ00121 PTZ00121
MAEBL; Provisional
12-298 8.10e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 8.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   12 RLSPNEEAFilkeDYERRRKLRLLQVREQERDIAlqirediKQRRNQQFTRLAEELRAEWEESQTQKIQNLEKLYLASLR 91
Cdd:PTZ00121 1071 GLKPSYKDF----DFDAKEDNRADEATEEAFGKA-------EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDA 1139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536   92 SMGEGHRQAKENEPDLDAlaqRAAERKRKADL--RHKEALKVQKNQKEILLKqKTWHIKARKEALLVEKERSAKitslpp 169
Cdd:PTZ00121 1140 RKAEEARKAEDAKRVEIA---RKAEDARKAEEarKAEDAKKAEAARKAEEVR-KAEELRKAEDARKAEAARKAE------ 1209
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530397536  170 ppptlfeniEVKRISAVKTNSSTyhhlhtfvNRETDTKRPDARLAAEEEAKRLEELQKQAAQERMERFEKAHVRGFQAMK 249
Cdd:PTZ00121 1210 ---------EERKAEEARKAEDA--------KKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAI 1272
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 530397536  250 KIHLAQNQEKLMK--------ELKQLQQEDLARRRQTVAQMPPQLVELPYKRSEMKE 298
Cdd:PTZ00121 1273 KAEEARKADELKKaeekkkadEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1329
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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