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Conserved domains on  [gi|564354392|ref|XP_006239575|]
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NAD kinase isoform X2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pnk super family cl28462
bifunctional NADP phosphatase/NAD kinase;
128-461 1.92e-93

bifunctional NADP phosphatase/NAD kinase;


The actual alignment was detected with superfamily member PLN02727:

Pssm-ID: 333282 [Multi-domain]  Cd Length: 986  Bit Score: 304.12  E-value: 1.92e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 128 QRLTWNKSPKSVLVIKKIRDAsLLQPFKELCIYLMEENNMIVYVEKKVLEDPA-IVGdenFGPVKkkfcTF-REDYDDIS 205
Cdd:PLN02727 670 QMLMWKSTPKTVLLLKKLGQE-LMEEAKEVASFLYHQEKMNVLVEPDVHDIFArIPG---FGFVQ----TFySQDTSDLH 741

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 206 NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAA-----VILRSRLKVRVVKe 280
Cdd:PLN02727 742 ERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR- 820

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 281 prdkktaihnglseNGldteggkQAMQ---YQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAA 357
Cdd:PLN02727 821 --------------NG-------KAMPgkvFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYST 879

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 358 AAGASMVHPNVPAIMVTPICPHSLSFRPIVVP--AGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPS 435
Cdd:PLN02727 880 AAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLELKI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPT 957

                        330       340
                 ....*....|....*....|....*.
gi 564354392 436 ICVCDPVSDWFESLAQCLHWNVRKKQ 461
Cdd:PLN02727 958 VNKSDQTGDWFRSLIRCLNWNERLDQ 983
 
Name Accession Description Interval E-value
PLN02727 PLN02727
NAD kinase
 128-461 1.92e-93

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 304.12  E-value: 1.92e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 128 QRLTWNKSPKSVLVIKKIRDAsLLQPFKELCIYLMEENNMIVYVEKKVLEDPA-IVGdenFGPVKkkfcTF-REDYDDIS 205
Cdd:PLN02727 670 QMLMWKSTPKTVLLLKKLGQE-LMEEAKEVASFLYHQEKMNVLVEPDVHDIFArIPG---FGFVQ----TFySQDTSDLH 741

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 206 NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAA-----VILRSRLKVRVVKe 280
Cdd:PLN02727 742 ERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR- 820

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 281 prdkktaihnglseNGldteggkQAMQ---YQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAA 357
Cdd:PLN02727 821 --------------NG-------KAMPgkvFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYST 879

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 358 AAGASMVHPNVPAIMVTPICPHSLSFRPIVVP--AGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPS 435
Cdd:PLN02727 880 AAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLELKI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPT 957

                        330       340
                 ....*....|....*....|....*.
gi 564354392 436 ICVCDPVSDWFESLAQCLHWNVRKKQ 461
Cdd:PLN02727 958 VNKSDQTGDWFRSLIRCLNWNERLDQ 983
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
137-458 2.08e-58

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 193.81  E-value: 2.08e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 137 KSVLVIKKIRDASLLQPFKELCIYLmEENNMIVYVEKKVLEDPAivgdenfgpvkkkfctfreDYDDISNQIDFIICLGG 216
Cdd:COG0061    2 KRIAIVAKPGKPEALEAAEELAELL-EERGIEVVLDEDTAVPGV-------------------PLEELGEEADLVIVLGG 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 217 DGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkeprdkktaihnglseng 296
Cdd:COG0061   62 DGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATV------------------- 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 297 ldTEGGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTgstayaaaagasMVHPNVPAIMVTPI 376
Cdd:COG0061  123 --DRDGEVVHEALALNEVVVLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTgstaynlsaggpIVHPGLDALVLTPI 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 377 CPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVCDPvsDWFESLAQCLHWN 456
Cdd:COG0061  201 APHTLSSRPLVLPDDSEIEIEVLEDSRP-AVLVADGQEVRDLEPGDRVEIRRSPKPVRLLRLKDH--SFFERLREKLGWG 277


                 ..
gi 564354392 457 VR 458
Cdd:COG0061  278 GD 279
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 311-436 1.23e-30

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 115.09  E-value: 1.23e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392  311 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPAIMVTPICPHSLSFRPIVVPA 390
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 564354392  391 GVELKIMlsPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSI 436
Cdd:pfam20143  81 SSKLRIR--VLSRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFI 124
 
Name Accession Description Interval E-value
PLN02727 PLN02727
NAD kinase
 128-461 1.92e-93

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 304.12  E-value: 1.92e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 128 QRLTWNKSPKSVLVIKKIRDAsLLQPFKELCIYLMEENNMIVYVEKKVLEDPA-IVGdenFGPVKkkfcTF-REDYDDIS 205
Cdd:PLN02727 670 QMLMWKSTPKTVLLLKKLGQE-LMEEAKEVASFLYHQEKMNVLVEPDVHDIFArIPG---FGFVQ----TFySQDTSDLH 741

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 206 NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAA-----VILRSRLKVRVVKe 280
Cdd:PLN02727 742 ERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR- 820

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 281 prdkktaihnglseNGldteggkQAMQ---YQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAA 357
Cdd:PLN02727 821 --------------NG-------KAMPgkvFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYST 879

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 358 AAGASMVHPNVPAIMVTPICPHSLSFRPIVVP--AGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPS 435
Cdd:PLN02727 880 AAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLELKI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPT 957

                        330       340
                 ....*....|....*....|....*.
gi 564354392 436 ICVCDPVSDWFESLAQCLHWNVRKKQ 461
Cdd:PLN02727 958 VNKSDQTGDWFRSLIRCLNWNERLDQ 983
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 130-461 4.14e-92

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 288.65  E-value: 4.14e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 130 LTWNKSPKSVLVIKKIRDASLLQPFKELCIYLMEENNMIVYVEKKVLEDpAIVGDENFGPVKKkfCTFREDYDDISNQID 209
Cdd:PLN02935 188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKE-LLSESSYFNFVQT--WEDEKEILLLHTKVD 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 210 FIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEPRdkktaih 289
Cdd:PLN02935 265 LVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHIIRDAA------- 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 290 nglsENGLDTEGgkqamQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVP 369
Cdd:PLN02935 338 ----KNEYETEE-----PILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVP 408

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 370 AIMVTPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVCDPVSDWFESL 449
Cdd:PLN02935 409 GILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRGQAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVESTNDFLRSI 488

                        330
                 ....*....|..
gi 564354392 450 AQCLHWNVRKKQ 461
Cdd:PLN02935 489 HDGLHWNLRKTQ 500
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
137-458 2.08e-58

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 193.81  E-value: 2.08e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 137 KSVLVIKKIRDASLLQPFKELCIYLmEENNMIVYVEKKVLEDPAivgdenfgpvkkkfctfreDYDDISNQIDFIICLGG 216
Cdd:COG0061    2 KRIAIVAKPGKPEALEAAEELAELL-EERGIEVVLDEDTAVPGV-------------------PLEELGEEADLVIVLGG 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 217 DGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkeprdkktaihnglseng 296
Cdd:COG0061   62 DGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATV------------------- 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 297 ldTEGGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTgstayaaaagasMVHPNVPAIMVTPI 376
Cdd:COG0061  123 --DRDGEVVHEALALNEVVVLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTgstaynlsaggpIVHPGLDALVLTPI 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 377 CPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVCDPvsDWFESLAQCLHWN 456
Cdd:COG0061  201 APHTLSSRPLVLPDDSEIEIEVLEDSRP-AVLVADGQEVRDLEPGDRVEIRRSPKPVRLLRLKDH--SFFERLREKLGWG 277


                 ..
gi 564354392 457 VR 458
Cdd:COG0061  278 GD 279
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
132-429 1.62e-37

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 144.49  E-value: 1.62e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 132 WNKSPKSVLVIKKIRDASLLQPFKELCIYLmEENNMIVYVEKKVLEdpaivgdenfgPVKKKFCTFREDYDDISNqIDFI 211
Cdd:PRK14076 286 WRIKPTKFGIVSRIDNEEAINLALKIIKYL-DSKGIPYELESFLYN-----------KLKNRLNEECNLIDDIEE-ISHI 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 212 ICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEPRDKKTaihng 291
Cdd:PRK14076 353 ISIGGDGTVLRASKLVNGEEIPIICINMGTVGFLTEFSKEEIFKAIDSIISGEYEIEKRTKLSGFILKDGHQNIL----- 427

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 292 lsengldteggkqamqYQVLNEVVI-DRGPSSYLsNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPA 370
Cdd:PRK14076 428 ----------------PSALNEVVItTKNPAKML-HFEVYVNGELVEEVRADGIIISTPTGSTAYSLSAGGPIVEPTVDG 490

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564354392 371 IMVTPICPHSLSFRPIVVPAGVELKIMLSpeaRNTAWVSFDGRKRQEIRHGDSISITTS 429
Cdd:PRK14076 491 FIIVPICPFKLSSRPLVVSANSEIKIKLL---KKSALVVIDGSIEFEAKKGDEIIFRKS 546
ppnK PRK01231
NAD(+) kinase;
133-458 3.22e-37

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 138.17  E-value: 3.22e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 133 NKSPKSVLVIKKIRDASLLQPFKELCIYLmEENNMIVYVEkkvlEDPAIVGDENFGPVKKkfctfREDYDDISnqiDFII 212
Cdd:PRK01231   1 MPSFRNIGLIGRLGSSSVVETLRRLKDFL-LDRGLEVILD----EETAEVLPGHGLQTVS-----RKLLGEVC---DLVI 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 213 CLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkepRDKKTAIHNGL 292
Cdd:PRK01231  68 VVGGDGSLLGAARALARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQEEERFLLEAEV----RRGGEVIGQGD 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 293 SengldteggkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPAIM 372
Cdd:PRK01231 144 A-----------------LNDVVLHPGKSTRMIEFELYIDGQFVCSQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAIV 206

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 373 VTPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSIcvcDPVS-DWFESLAQ 451
Cdd:PRK01231 207 LVPMFPHTLSSRPIVVDGNSEIKIVISKDNRTYPRVSCDGQNSVTLAPGDTVTIRKKPQKLRLI---HPLDyNYYETCRT 283


                 ....*..
gi 564354392 452 CLHWNVR 458
Cdd:PRK01231 284 KLGWGSR 290
ppnK PRK02155
NAD kinase;
200-456 1.15e-32

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 125.82  E-value: 1.15e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 200 DYDDISNQIDFIICLGGDGTLL-YASSLFQGSVPPVMAFHlGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVV 278
Cdd:PRK02155  56 TPEEIGARADLAVVLGGDGTMLgIGRQLAPYGVPLIGINH-GRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEARVV 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 279 kepRDKKTaIHNGLSengldteggkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAA 358
Cdd:PRK02155 135 ---RDGEP-IFHALA-----------------FNDVVVNRSGFSGMVELRVSVDGRFMYNQRSDGLIVATPTGSTAYALS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 359 AGASMVHPNVPAIMVTPICPHSLSFRPIVVPAGVELKIMLSpEARNTAwVSFDGRKRQEIRHGDSISITTSCYplpSICV 438
Cdd:PRK02155 194 AGGPILHPQLPGWVLVPIAPHTLSNRPIVLPDDSEVAIQIV-GGRDVS-VNFDMQSLTSLELGDRIEVRRSPH---TVRF 268

                        250
                 ....*....|....*....
gi 564354392 439 CDPVS-DWFESLAQCLHWN 456
Cdd:PRK02155 269 LHPVGySYYATLRKKLHWN 287
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 311-436 1.23e-30

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 115.09  E-value: 1.23e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392  311 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPAIMVTPICPHSLSFRPIVVPA 390
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 564354392  391 GVELKIMlsPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSI 436
Cdd:pfam20143  81 SSKLRIR--VLSRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFI 124
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 151-458 2.14e-29

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 116.88  E-value: 2.14e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 151 LQPFKELCIYLMEENNMIVYVEKKVLEDPAIVGDENFGpvkkkfCTFReDYDDISNQIDFIICLGGDGTLLYASSLFQGS 230
Cdd:PRK04539  19 IQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVG------CHIV-NKTELGQYCDLVAVLGGDGTFLSVAREIAPR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 231 VPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEprdkktaihnglsengldtegGKQAMQYQV 310
Cdd:PRK04539  92 AVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIRE---------------------GKTAERALA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 311 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPAIMVTPICPHSLSFRPIVVPA 390
Cdd:PRK04539 151 LNDAVLSRGGAGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPD 230

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564354392 391 GVELKIMLSP--EARntawVSFDGRKRQEIRHGDSISITTSCYPLPsicVCDPVS-DWFESLAQCLHWNVR 458
Cdd:PRK04539 231 TSEIEILVTQggDAR----VHFDGQTHIDVQNLDRITIRRYRNPLR---ILHPTDyQYFKTLRQKLHWGEQ 294
ppnK PRK03708
NAD(+) kinase;
192-429 4.05e-28

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 112.88  E-value: 4.05e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 192 KKFCTFRE-DYDDISN-QIDFIICLGGDGTLLYASSLFQGSVPpVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVil 269
Cdd:PRK03708  40 EHLPEFSEeDVLPLEEmDVDFIIAIGGDGTILRIEHKTKKDIP-ILGINMGTLGFLTEVEPEETFFALSRLLEGDYFI-- 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 270 RSRLKVRVvkeprdkktaIHNGlsENGLDteggkqamqyqVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTP 349
Cdd:PRK03708 117 DERIKLRV----------YING--ENVPD-----------ALNEVVILTGIPGKIIHLKYYVDGELADEVRADGLIISTP 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 350 TGSTAYAAAAGASMVHPNVPAIMVTPICPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSISITTS 429
Cdd:PRK03708 174 TGSTAYAMSAGGPFVDPRLDAILIAPLCPFKLSSRPMVVPSSSRIDVKLLRTGRE-IILVIDGQYYEELPPDTEITIKKS 252
ppnK PRK01185
NAD(+) kinase;
209-429 9.71e-28

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 111.44  E-value: 9.71e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 209 DFIICLGGDGTLLYASSLFQGsvpPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkeprdkktai 288
Cdd:PRK01185  54 DVIITIGGDGTILRTLQRAKG---PILGINMGGLGFLTEIEIDEVGSAIKKLIRGEYFIDERMKLKVYI----------- 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 289 hnglseNGLDTeggkqamqYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNV 368
Cdd:PRK01185 120 ------NGERL--------EDCTNEAVIHTDRIAKIRQFKIYYDGHFLDTFKADGVIVATPTGSTSYSSSAGGPILLPNL 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564354392 369 PAIMVTPICPHSLSFRPIVVPAGVELKIMLSPEARNTawVSFDGRKRQEIRHGDSISITTS 429
Cdd:PRK01185 186 EGMVISYIAPYSSRPKSVVVPSESTVEIKIAGDQSSL--LILDGQYEYKISKGDTVEISKS 244
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 152-413 1.47e-27

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 111.55  E-value: 1.47e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 152 QPFKELCIYLMEENNMIVYVEKKVLEdpAIVGDENFGPVKKKFCTFredyDDISNQIDFIICLGGDGTLLYASSLFQGSV 231
Cdd:PRK01911  15 SPYIQELFDELEERGAEVLIEEKFLD--FLKQDLKFHPSYDTFSDN----EELDGSADMVISIGGDGTFLRTATYVGNSN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 232 PPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRvvkeprdkktaihnglSENGLDTEggkqaMQYqVL 311
Cdd:PRK01911  89 IPILGINTGRLGFLATVSKEEIEETIDELLNGDYTIEERSLLQLE----------------SNPKLFGE-----LNF-AL 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 312 NEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPAIMVTPICPHSLSFRPIVVPAG 391
Cdd:PRK01911 147 NEIAILKRDTSSMITVHTYLNGEYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHNLNVRPLVIPDD 226

                        250       260
                 ....*....|....*....|...
gi 564354392 392 VElkIMLSPEARNTAW-VSFDGR 413
Cdd:PRK01911 227 TE--ITLEVESRSDNFlVSLDSR 247
pnk PRK14077
NAD(+) kinase;
202-455 4.26e-24

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 101.78  E-value: 4.26e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 202 DDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKep 281
Cdd:PRK14077  59 DELFKISDFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLTDITVDEAEKFFQAFFQGEFEIEKPYMLSVFLEK-- 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 282 RDKKTaihnglsengldteggkqaMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGA 361
Cdd:PRK14077 137 KQGKI-------------------LEKLAFNDVVISKNNQASMAHIEAFLNEKYFNEYFGDGVIVATPAGSTAYNMSANG 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 362 SMVHPNVPAIMVTPICPHSLSFRPIVVPAGVELKIMlspeARNTAWVSFDGRKRQEIRHGDSISITTScypLPSICVCDP 441
Cdd:PRK14077 198 PIIYPLSQVFILTPVCSHSLTQRPIVLPKGFEVEFK----TKSDCILCIDGQDRYKMNDFKSIKVGLS---DKNVALIRH 270

                        250
                 ....*....|....*
gi 564354392 442 VS-DWFESLAQCLHW 455
Cdd:PRK14077 271 KNrDYFQILKEKLHW 285
ppnK PRK02645
NAD(+) kinase;
205-455 5.78e-24

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 101.53  E-value: 5.78e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 205 SNQIDFIICLGGDGTLLYAS-SLFQGSVPpVMAFHLG-SLGFLT-PFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEP 281
Cdd:PRK02645  55 SELIDLAIVLGGDGTVLAAArHLAPHDIP-ILSVNVGgHLGFLThPRDLLQDESVWDRLQEDRYAIERRMMLQARVFEGD 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 282 RDKKTAIhnglSENgldteggkqamqYQVLNE-----VVIDRGPSSYLsnvDVYLDGHLITTVQGDGVIVSTPTGSTAYA 356
Cdd:PRK02645 134 RSNEEPV----SES------------YYALNDfylkpASEDRSPTCIL---ELEIDGEVVDQYQGDGLIVSTPTGSTAYT 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 357 AAAGASMVHPNVPAIMVTPICPHSLSFRPIVVPAG--VELKIMLSPEARNTAWVsfDGRKRQEIRHGDSISITTSCYPlP 434
Cdd:PRK02645 195 MAAGGPILHPGIDAIIVTPICPMSLSSRPIVIPPGsrVVIWPLGDYDLNIKLWK--DGVLATSIWPGQRCVIQKARHP-A 271

                        250       260
                 ....*....|....*....|.
gi 564354392 435 SICVCDPVSDWFESLAQCLHW 455
Cdd:PRK02645 272 KFIILEESYSYYRTLREKLHW 292
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 141-433 1.37e-22

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 97.32  E-value: 1.37e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 141 VIKKIRDASLLQPFKELCIYLMEeNNMIVYVEKKVLEDPAIVgDENFGpvkkkfctfreDYDDISNQIDFIICLGGDGTL 220
Cdd:PRK03378  10 IVGHPRHPTALTTHEMLYHWLTS-KGYEVIVEQQIAHELQLK-NVKTG-----------TLAEIGQQADLAIVVGGDGNM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 221 LYAS---SLFQGSVPPVmafHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKeprdkktaiHNGLSENGL 297
Cdd:PRK03378  77 LGAArvlARYDIKVIGI---NRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCR---------HGQQKRIST 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 298 dteggkqamqyqVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPAIMVTPIC 377
Cdd:PRK03378 145 ------------AINEVVLHPGKVAHMIEFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMF 212

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564354392 378 PHSLSFRPIVVPAGVELKIMLSPEaRNTAWVSFDGRKRQEIRHGDSISITTSCYPL 433
Cdd:PRK03378 213 PHTLSARPLVIDSSSTIRLKFSPN-RSDLEISCDSQIALPIQPGEEVLIRRSDYHL 267
ppnK PRK02649
NAD(+) kinase;
208-455 6.61e-19

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 86.96  E-value: 6.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 208 IDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTpfnfENFQSQVN----QVIEGNAAVILRSRLKVRVVKEprd 283
Cdd:PRK02649  69 MKFAIVLGGDGTVLSAARQLAPCGIPLLTINTGHLGFLT----EAYLNQLDeaidQVLAGQYTIEERTMLTVSVMRG--- 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 284 kKTAIHNGLSengldteggkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASM 363
Cdd:PRK02649 142 -DQLRWEALS-----------------LNEMVLHREPLTSMCHFEIAIGRHAPVDIAADGVILSTPTGSTAYSLSAGGPV 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 364 VHPNVPAIMVTPICPHSLSFRPIVVPAGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVCDPvs 443
Cdd:PRK02649 204 ITPDVPVLQLTPICPHSLASRALVFSDSEPVTV--FPATPERLVMVVDGNAGCYVWPEDRVLIRRSPYPVRFIRLQDP-- 279

                        250
                 ....*....|..
gi 564354392 444 DWFESLAQCLHW 455
Cdd:PRK02649 280 EFFRVLREKLGW 291
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 139-262 5.95e-16

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 74.32  E-value: 5.95e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392  139 VLVIKKIRDASLLQPFKELCIYLMEENNMIVYVEKKV-------LEDPAIVGDENFGPVK---KKFCTFREdyddisNQI 208
Cdd:pfam01513   1 VGIVVNPDKKEALERAREVARWLLDRLGITVTVEEKMgeslafaAGDRPEVIGCLKKVVDdtrRATRAFAD------AGV 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 564354392  209 DFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIE 262
Cdd:pfam01513  75 DLIIVLGGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLLE 128
pnk PRK14075
NAD(+) kinase;
208-389 2.35e-15

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 75.92  E-value: 2.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 208 IDFIICLGGDGTLLYASSLFQGsvpPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKeprdkkta 287
Cdd:PRK14075  42 ADLIIVVGGDGTVLKAAKKVGT---PLVGFKAGRLGFLSSYTLEEIDRFLEDLKNWNFREEKRWFLKIESEL-------- 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 288 ihnglsengldteggkqaMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHPN 367
Cdd:PRK14075 111 ------------------GNHLALNDVTLERDPSQKMVEIEVSFEDHSSMWFFADGVVISTPTGSTAYSLSLGGPIILPN 172

                        170       180
                 ....*....|....*....|..
gi 564354392 368 VPAIMVTPICPHSLSFRPIVVP 389
Cdd:PRK14075 173 CEVFEITPIAPQFLATRSIVIP 194
ppnK PRK02231
NAD(+) kinase;
202-433 2.38e-15

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 76.00  E-value: 2.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 202 DDISNQIDFIICLGGDGTLL-YASSLFQGSVPpVMAFHLGSLGFLTPFNFENFQSQVNQVIE-GNAAVILRSRLKVRVVK 279
Cdd:PRK02231  37 EEIGQRAQLAIVIGGDGNMLgRARVLAKYDIP-LIGINRGNLGFLTDIDPKNAYEQLEACLErGEFFVEERFLLEAKIER 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 280 EprdkktaihnglsengldtegGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAA 359
Cdd:PRK02231 116 N---------------------GKIIATSNALNEVVIHPAKIAHMIDFHVYIDDKFAFSQRSDGLIISTPTGSTAYSLSA 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564354392 360 GASMVHPNVPAIMVTPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPL 433
Cdd:PRK02231 175 GGPILTPNLNAIALVPMFPHTLSSRPLVIDGDSKISLRFAEYNTPQLEVSCDSQIALPFTPDDRVHVQKSPDKL 248
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 207-433 6.35e-15

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 75.34  E-value: 6.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 207 QIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkepRDKKT 286
Cdd:PRK03372  72 GCELVLVLGGDGTILRAAELARAADVPVLGVNLGHVGFLAEAEAEDLDEAVERVVDRDYRVEERMTLDVTV----RVGGE 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 287 AIHNGLSengldteggkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMVHP 366
Cdd:PRK03372 148 IVWRGWA-----------------LNEASLEKADREGMLEVVLEVDGRPVSSFGCDGVLVSTPTGSTAYAFSAGGPVVWP 210

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564354392 367 NVPAIMVTPICPHSLSFRPIVVPAGVELKIMLSPEArNTAWVSFDGRKRQEIRHGDSISITTSCYPL 433
Cdd:PRK03372 211 DLEALLVVPLNAHALFARPLVVSPTSTVAVEILADT-SDAVLWCDGRRSVDLPPGARVEVRRGATPV 276
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 191-426 9.67e-11

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 62.14  E-value: 9.67e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 191 KKKFCTFREDYDDisNQIDFIICLGGDGTLLYASSLFQGSVPPVmAF---HLGSLGFLT---PFNFENFqsqVNQVIEGN 264
Cdd:PRK04885  21 KKYLKDFGFILDE--KNPDIVISVGGDGTLLSAFHRYENQLDKV-RFvgvHTGHLGFYTdwrPFEVDKL---VIALAKDP 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 265 AAVILRSRLKVRVVkeprdkktaihnglsengldTEGGKQAmQYQVLNEVVIDRgPSSYLSnVDVYLDGHLITTVQGDGV 344
Cdd:PRK04885  95 GQVVSYPLLEVKIT--------------------YEDGEKE-KYLALNEATIKR-IEGTLV-ADVYINGVLFERFRGDGL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 345 IVSTPTGSTAYAAAAGASMVHPNVPAIMVTPICphSLS---FR----PIVVPAGVelKIMLSPEARNTAWVSFDgrkRQE 417
Cdd:PRK04885 152 CVSTPTGSTAYNKSLGGAVLHPSIEALQLTEIA--SINnrvFRtlgsPLILPKHH--TITLKPVNDDDYQITVD---HLT 224


                 ....*....
gi 564354392 418 IRHGDSISI 426
Cdd:PRK04885 225 IKHKNVKSI 233
ppnK PRK03501
NAD kinase;
211-429 1.75e-04

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 43.04  E-value: 1.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 211 IICLGGDGTLLYA--------SSLFQGsvppVMAfhLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkepr 282
Cdd:PRK03501  43 IVSIGGDGTFLQAvrktgfreDCLYAG----IST--KDQLGFYCDFHIDDLDKMIQAITKEEIEVRKYPTIEVTV----- 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 283 dkktaihnglsengldteggKQAMQYQVLNEVVIDrgpSSYLSN--VDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAG 360
Cdd:PRK03501 112 --------------------DGSTSFYCLNEFSIR---SSIIKTfvIDVYIDDLHFETFRGDGMVVSTPTGSTAYNKSVR 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564354392 361 ASMVHPNVPAIMVTPICphSL---SFR----PIVVPAGVELKIMLSPEARNTAWVSFDGrKRQEIRHGDSISITTS 429
Cdd:PRK03501 169 GAVVDPLIPCFQVSELA--SLnnnTYRtlgsPFILSHERKLTLKIVQDGNDYPIIGMDN-EALSIKHVEKIDIRLS 241
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 201-349 1.42e-03

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 40.19  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 201 YDDIS-NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFL-TPFNFENFQSQVNqviEGNAAVIlrSRLKVRVV 278
Cdd:PRK04761  18 YGDVPiEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLmNEYSEDDLLERIA---AAEPTVL--HPLRMTAT 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564354392 279 KEPRDKKTAIhnglsengldteggkqamqyqVLNEVVIDRGpSSYLSNVDVYLDGHL-ITTVQGDGVIVSTP 349
Cdd:PRK04761  93 DVSGEVHEAL---------------------AINEVSLFRQ-TRQAAKLRISIDGKVrMEELVCDGVLVATP 142
ppnK PRK00561
NAD(+) kinase;
189-426 5.97e-03

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 38.32  E-value: 5.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 189 PVKKKFCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNF----ENFQSQVNQVIEGN 264
Cdd:PRK00561  15 PVLPKLKKVLKKKLAVEDGADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYTSFNEtdldQNFANKLDQLKFTQ 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 265 AAVIlrsRLKVrvvkeprdkktaihnglsengldteggkQAMQYQVLNEVVIDrgpSSYLSNVDVYLDGHLITTVQGDGV 344
Cdd:PRK00561  95 IDLL---EVQI----------------------------DDQIHLVLNELAVY---TNTAYPINIFIDNEFWEKYRGSGL 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 345 IVSTPTGSTAYAAAAGASMVHPNVPAIMVTPICP--HSlSF----RPIVVPAGVELKIMLSPEARNTAWVSF--DGRKRQ 416
Cdd:PRK00561 141 LIGPRTGSTALAKSAKGAVIFPRIDVIQIIELNPllHP-NQttiqSPIILPIDTKVEFEIKKAFDHDQFPRFyaDGAKLR 219

                        250
                 ....*....|
gi 564354392 417 EIRHGDSISI 426
Cdd:PRK00561 220 LGNSDTTIEI 229
PLN02929 PLN02929
NADH kinase
 195-277 5.98e-03

NADH kinase


Pssm-ID: 215502 [Multi-domain]  Cd Length: 301  Bit Score: 38.48  E-value: 5.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564354392 195 CTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPvmafhLG----------------------SLGFLTPFNFEN 252
Cdd:PLN02929  52 CVLRNELSQPIRDVDLVVAVGGDGTLLQASHFLDDSIPV-----LGvnsdptqkdeveeysdefdarrSTGHLCAATAED 126

                         90       100
                 ....*....|....*....|....*
gi 564354392 253 FQSQVNQVIEGNAAVILRSRLKVRV 277
Cdd:PLN02929 127 FEQVLDDVLFGRLKPTELSRISTVV 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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