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Conserved domains on  [gi|568918950|ref|XP_006500503|]
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ribosome-binding protein 1 isoform X1 [Mus musculus]

Protein Classification

Rib_recp_KP_reg and SMC_prok_B domain-containing protein( domain architecture ID 13707826)

Rib_recp_KP_reg and SMC_prok_B domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 810-1422 8.73e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.29  E-value: 8.73e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   810 LVAREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLEnGPNTQLARLQQENSILRDALNQATSQVeSKQNTELAKL 889
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE-ELRLEVSELEEEIEELQKELYALANEI-SRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   890 RQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASH-----------------KESEEALQKRLEEVTRE 952
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELesleaeleeleaeleelESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   953 LCRAQTSHANLRADAEKAQEQQQRVAELHSKLQS--SEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQ 1030
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQeiEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1031 AQDTQASHA------EANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDL---------REKNWKAMEAlalaer 1095
Cdd:TIGR02168  468 EELEEAEQAldaaerELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvDEGYEAAIEA------ 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1096 ACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISA------HQNYAEWLQEFKEKGSELLKKPPTLEPSMD-- 1167
Cdd:TIGR02168  542 ALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSyl 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1168 -----IVLKLREAEETQNSLQAEcdqYRTILAE--------------TEGMLKDLQKSVEEEERvwKAKVGAAEEELHKS 1228
Cdd:TIGR02168  622 lggvlVVDDLDNALELAKKLRPG---YRIVTLDgdlvrpggvitggsAKTNSSILERRREIEEL--EEKIEELEEKIAEL 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1229 RVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDE 1308
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1309 LALLKTQLERTEATLEAEQTRRQKLTAEFEEAqrtacriQEELEKLRaagplessgkEEITQLKERLEKEKRLTSDLGRA 1388
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDEL-------RAELTLLN----------EEAANLRERLESLERRIAATERR 839

                          650       660       670
                   ....*....|....*....|....*....|....
gi 568918950  1389 AIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAED 1422
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEIEELEELIEELES 873
2A1904 super family cl36772
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 260-513 3.44e-12

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


The actual alignment was detected with superfamily member TIGR00927:

Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 71.57  E-value: 3.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   260 KGEGGQNQAKkGEGAQNQGKKGEGAQnqGKKGEGAQNQAKKGEGAQNQAK-KGEGAQNQGKKGEGAQNQSKKGEGAQNqa 338
Cdd:TIGR00927  632 KGDVAEAEHT-GERTGEEGERPTEAE--GENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH-- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   339 kKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQ 418
Cdd:TIGR00927  707 -KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQA 785

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   419 GK----KGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQ-GKKGEGAQNQGKKGE 493
Cdd:TIGR00927  786 GEdgemKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEkGVDGGGGSDGGDSEE 865

                          250       260
                   ....*....|....*....|
gi 568918950   494 GAQNQGKKGEGAQNQGKKGE 513
Cdd:TIGR00927  866 EEEEEEEEEEEEEEEEEEEE 885
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
 33-168 2.40e-10

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


:

Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 60.14  E-value: 2.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950    33 MKETSYEEALANQRKEMAKTHhQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKE---PVRVSAVAVAP 109
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTP-TEKEKKKKEKKKEKKKKSKKKEEKPNGKLPESEQADESEEEPREfktPDEAPSAALEP 79

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568918950   110 TSVhSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSA 168
Cdd:pfam05104   80 EPV-PTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEE 137
2A1904 super family cl36772
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 421-644 3.38e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


The actual alignment was detected with superfamily member TIGR00927:

Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 58.47  E-value: 3.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   421 KGEAAQKQDKKiEGAQNQGKKPEGTsnQGKKGEGAQNQGKKGEGAQNQGK-KGEGAQNQGKKGEGAQNQGKKGEGAQNqg 499
Cdd:TIGR00927  632 KGDVAEAEHTG-ERTGEEGERPTEA--EGENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH-- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   500 kKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGK-KGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQ 578
Cdd:TIGR00927  707 -KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEgEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQA 785

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568918950   579 GKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEgvsNQVKKSEGSPNQGKKAEGAPNQGKKKDG 644
Cdd:TIGR00927  786 GEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSE---TQADDTEVKDETGEQELNAENQGEAKQD 848
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 810-1422 8.73e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.29  E-value: 8.73e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   810 LVAREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLEnGPNTQLARLQQENSILRDALNQATSQVeSKQNTELAKL 889
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE-ELRLEVSELEEEIEELQKELYALANEI-SRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   890 RQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASH-----------------KESEEALQKRLEEVTRE 952
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELesleaeleeleaeleelESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   953 LCRAQTSHANLRADAEKAQEQQQRVAELHSKLQS--SEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQ 1030
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQeiEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1031 AQDTQASHA------EANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDL---------REKNWKAMEAlalaer 1095
Cdd:TIGR02168  468 EELEEAEQAldaaerELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvDEGYEAAIEA------ 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1096 ACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISA------HQNYAEWLQEFKEKGSELLKKPPTLEPSMD-- 1167
Cdd:TIGR02168  542 ALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSyl 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1168 -----IVLKLREAEETQNSLQAEcdqYRTILAE--------------TEGMLKDLQKSVEEEERvwKAKVGAAEEELHKS 1228
Cdd:TIGR02168  622 lggvlVVDDLDNALELAKKLRPG---YRIVTLDgdlvrpggvitggsAKTNSSILERRREIEEL--EEKIEELEEKIAEL 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1229 RVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDE 1308
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1309 LALLKTQLERTEATLEAEQTRRQKLTAEFEEAqrtacriQEELEKLRaagplessgkEEITQLKERLEKEKRLTSDLGRA 1388
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDEL-------RAELTLLN----------EEAANLRERLESLERRIAATERR 839

                          650       660       670
                   ....*....|....*....|....*....|....
gi 568918950  1389 AIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAED 1422
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEIEELEELIEELES 873
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 821-1412 2.01e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 2.01e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  821 QARMQASYRDHVKEVQQLQG-----KIRTLQEQLENGpNTQLARLQQENSILRDALNQATSQVESKQNtELAKLRQELSK 895
Cdd:COG1196   208 QAEKAERYRELKEELKELEAellllKLRELEAELEEL-EAELEELEAELEELEAELAELEAELEELRL-ELEELELELEE 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  896 VNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQ 975
Cdd:COG1196   286 AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  976 RVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQV 1055
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1056 ScLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERAcEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSI 1135
Cdd:COG1196   446 E-AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE-LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1136 SAHQNYAEWLQEFKEKGSELLkkpptLEPSMDIVLKLREAEETQNSLQAECDQYR-TILAETEGMLKDLQKSVEEEERVW 1214
Cdd:COG1196   524 GAVAVLIGVEAAYEAALEAAL-----AAALQNIVVEDDEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIG 598

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1215 KAKVGAAEEELHKSRVTVKHLEDIVEK--LKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQ 1292
Cdd:COG1196   599 AAVDLVASDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1293 SQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLR--------AAGPLESSG 1364
Cdd:COG1196   679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELleeeelleEEALEELPE 758

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568918950 1365 KEEITQLKERLEKEKRLTSDLGR---AAIKLQELLKTTQEQLTKEKDTVKK 1412
Cdd:COG1196   759 PPDLEELERELERLEREIEALGPvnlLAIEEYEELEERYDFLSEQREDLEE 809
PTZ00121 PTZ00121
MAEBL; Provisional
 861-1428 1.25e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 76.33  E-value: 1.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  861 QQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKElVEKSEASRQEEQQRKALEAKAATFEKQV-----LQLQASH 935
Cdd:PTZ00121 1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEE-ARKAEDARKAEEARKAEDAKRVEIARKAedarkAEEARKA 1172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  936 KESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKeaRAENSQL 1015
Cdd:PTZ00121 1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAK--KAEEERN 1250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1016 TERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLR---EKNWKAMEALAL 1092
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKkadEAKKKAEEAKKK 1330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1093 AERA---CEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIV 1169
Cdd:PTZ00121 1331 ADAAkkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL 1410

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1170 LKLREAEETQNSLQAECDQYRTI------------------LAETEGMLKDLQKSVEEEERVWKAKVGAAE----EELHK 1227
Cdd:PTZ00121 1411 KKAAAAKKKADEAKKKAEEKKKAdeakkkaeeakkadeakkKAEEAKKAEEAKKKAEEAKKADEAKKKAEEakkaDEAKK 1490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1228 SRVTVKHLEDIVEKLKGELESSDQVREHTSHLEA-ELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQS 1306
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAdEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1307 DELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACR--IQEELEKLRAAG-PLESSGKEEITQLKERLEKEKRLTS 1383
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEeaKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAE 1650

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568918950 1384 DLGRA----AIKLQELLKTTQE------QLTKEKDTVKKLQEQLGKAEDGSSSKE 1428
Cdd:PTZ00121 1651 ELKKAeeenKIKAAEEAKKAEEdkkkaeEAKKAEEDEKKAAEALKKEAEEAKKAE 1705
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 260-513 3.44e-12

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 71.57  E-value: 3.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   260 KGEGGQNQAKkGEGAQNQGKKGEGAQnqGKKGEGAQNQAKKGEGAQNQAK-KGEGAQNQGKKGEGAQNQSKKGEGAQNqa 338
Cdd:TIGR00927  632 KGDVAEAEHT-GERTGEEGERPTEAE--GENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH-- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   339 kKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQ 418
Cdd:TIGR00927  707 -KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQA 785

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   419 GK----KGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQ-GKKGEGAQNQGKKGE 493
Cdd:TIGR00927  786 GEdgemKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEkGVDGGGGSDGGDSEE 865

                          250       260
                   ....*....|....*....|
gi 568918950   494 GAQNQGKKGEGAQNQGKKGE 513
Cdd:TIGR00927  866 EEEEEEEEEEEEEEEEEEEE 885
PTZ00121 PTZ00121
MAEBL; Provisional
 188-685 9.67e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 70.17  E-value: 9.67e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  188 KASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNqgKKGEGAQNQAKKGEGGQNQ 267
Cdd:PTZ00121 1291 KADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAK--AEAEAAADEAEAAEEKAEA 1368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  268 AKKGEgaQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEggqnQ 347
Cdd:PTZ00121 1369 AEKKK--EEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE----E 1442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  348 AKKGEGAQNQAKKGEGAQNQAKKGEgvqnqAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQK 427
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEAKKKAE-----EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKK 1517

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  428 QDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKgegAQNQGKKGEGAQN 507
Cdd:PTZ00121 1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALR---KAEEAKKAEEARI 1594

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  508 QGKKGEGAQNQGKKGEgpqnQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQG----KKAEGVQSQSKKGEGTQNQ-GKKG 582
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAE----EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEaeekKKAEELKKAEEENKIKAAEeAKKA 1670

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  583 DGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSpnQGKKAEGAPNQGKKKDGSPSQAKKvDAAANQGKKS 662
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAE--EKKKAEELKKAEEENKIKAEEAKK-EAEEDKKKAE 1747

                         490       500
                  ....*....|....*....|...
gi 568918950  663 EMAPAQGQKASMVQSQEAPKQDA 685
Cdd:PTZ00121 1748 EAKKDEEEKKKIAHLKKEEEKKA 1770
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 829-1417 1.23e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 66.40  E-value: 1.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   829 RDHVKEVQQLQGKIRTLQEQLENgPNTQLARLQQENSILRDALNQATSQVESKQnTELAKLRQELSKVNKELVEKSEASR 908
Cdd:pfam12128  230 IQAIAGIMKIRPEFTKLQQEFNT-LESAELRLSHLHFGYKSDETLIASRQEERQ-ETSAELNQLLRTLDDQWKEKRDELN 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   909 QE-----------EQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEK-----AQE 972
Cdd:pfam12128  308 GElsaadaavakdRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRrrskiKEQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   973 QQQRVAELHSKLQSS-EVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEA------GQAQDTQASHAEANQQQ 1045
Cdd:pfam12128  388 NNRDIAGIKDKLAKIrEARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSrlgelkLRLNQATATPELLLQLE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1046 TRLKELESQVSCLEKETSELKEAMEQQKgknnDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHlaeaqtkeT 1125
Cdd:pfam12128  468 NFDERIERAREEQEAANAEVERLQSELR----QARKRRDQASEALRQASRRLEERQSALDELELQLFPQAG--------T 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1126 LLALLpglsisaHQNYAEWLQEF-KEKGSELLKKpPTLEPSMDIV----------LKLREAEETQNSLQAECDQYRTILA 1194
Cdd:pfam12128  536 LLHFL-------RKEAPDWEQSIgKVISPELLHR-TDLDPEVWDGsvggelnlygVKLDLKRIDVPEWAASEEELRERLD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1195 ETEGML---KDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELES------------SDQVREHTSHL 1259
Cdd:pfam12128  608 KAEEALqsaREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSekdkknkalaerKDSANERLNSL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1260 EAELE----KHMAA----------ASAECQNYAKEVAGLRQLLLesqSQLDEAKSEAQKQSD-ELALLKTQLERTEATLE 1324
Cdd:pfam12128  688 EAQLKqldkKHQAWleeqkeqkreARTEKQAYWQVVEGALDAQL---ALLKAAIAARRSGAKaELKALETWYKRDLASLG 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1325 AEQTRRQKLTAEFEEAQRTACRI-QEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQL 1403
Cdd:pfam12128  765 VDPDVIAKLKREIRTLERKIERIaVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKL 844

                          650
                   ....*....|....
gi 568918950  1404 TKEKDTVKKLQEQL 1417
Cdd:pfam12128  845 EMERKASEKQQVRL 858
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
 33-168 2.40e-10

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 60.14  E-value: 2.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950    33 MKETSYEEALANQRKEMAKTHhQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKE---PVRVSAVAVAP 109
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTP-TEKEKKKKEKKKEKKKKSKKKEEKPNGKLPESEQADESEEEPREfktPDEAPSAALEP 79

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568918950   110 TSVhSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSA 168
Cdd:pfam05104   80 EPV-PTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEE 137
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 421-644 3.38e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 58.47  E-value: 3.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   421 KGEAAQKQDKKiEGAQNQGKKPEGTsnQGKKGEGAQNQGKKGEGAQNQGK-KGEGAQNQGKKGEGAQNQGKKGEGAQNqg 499
Cdd:TIGR00927  632 KGDVAEAEHTG-ERTGEEGERPTEA--EGENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH-- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   500 kKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGK-KGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQ 578
Cdd:TIGR00927  707 -KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEgEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQA 785

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568918950   579 GKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEgvsNQVKKSEGSPNQGKKAEGAPNQGKKKDG 644
Cdd:TIGR00927  786 GEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSE---TQADDTEVKDETGEQELNAENQGEAKQD 848
Gag_spuma pfam03276
Spumavirus gag protein;
347-478 2.37e-06

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 52.06  E-value: 2.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   347 QAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVE---GAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQ----NQG 419
Cdd:pfam03276  480 QIRASRGPGPGPSAGEGRGGPANEGRGGPCNAGGGNDcgaNGQNDGGENIQNGGQELRSQGGQNLRSGGGQGQrwgeGRG 559

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568918950   420 KKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGegaqNQGKKGEGAQNQGKKGEGAQNQ 478
Cdd:pfam03276  560 NRENENTENSEQRPREIQAGSGRPGNAGQGVKG----AAGQGGKGAAGRGGRGNGAGDQ 614
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 211-569 1.73e-05

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 49.23  E-value: 1.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  211 GEGAQNQGKKGEGAqnqakkGEGAQNQAKKGEGAQNQGKKGEGAQN---QAKKGEGGQNQAKKGE-GAQNQGKKGEGAQN 286
Cdd:cd21118    24 GEGTGAGESAGHGL------GDAISHGIGEAVGQGAKEAASSGIQNalgQGHGEEGGSTLGSRGDvFEHRLGEAARSLGN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  287 QGKK-GEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAqNQAKKGEGGQNQAKKGEGAQNQAKKGeGAQ 365
Cdd:cd21118    98 AGNEiGRQAEDIIRHGVDAVHNSWQGSGGHGAYGSQGGPGVQGHGIPGG-TGGPWASGGNYGTNSLGGSVGQGGNG-GPL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  366 NQAKKGEGVQNQAKKGVEGAQNQgKKGEANQNQAKKGEGGQNQTKKgegpqnqgkkgeaaqkqdkkiEGAQNQGKKPEGT 445
Cdd:cd21118   176 NYGTNSQGAVAQPGYGTVRGNNQ-NSGCTNPPPSGSHESFSNSGGS---------------------SSSGSSGSQGSHG 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  446 SNQGKKGEGAQNQGKKGEGAQNQGKKG-EGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGeGAQNQGKKGEG 524
Cdd:cd21118   234 SNGQGSSGSSGGQGNGGNNGSSSSNSGnSGGSNGGSSGNSGSGSGGSSSGGSNGWGGSSSSGGSGGSG-GGNKPECNNPG 312

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 568918950  525 PQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQS 569
Cdd:cd21118   313 NDVRMAGGGGSQGSKESSGSHGSNGGNGQAEAVGGLNTLNSDAST 357
Gag_spuma pfam03276
Spumavirus gag protein;
449-598 3.79e-04

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 45.12  E-value: 3.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   449 GKKGEGAQNQGKKGEG-AQNQGKKGEGAQNQGKKGE-GAQNQGKKGEGAQNQGkkGEGAQNQGK--KGEGAQNQGKKGEG 524
Cdd:pfam03276  473 GLAARGPQIRASRGPGpGPSAGEGRGGPANEGRGGPcNAGGGNDCGANGQNDG--GENIQNGGQelRSQGGQNLRSGGGQ 550

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568918950   525 PQNQakkgegAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGegtqNQGKKGDGNPNQGKKGEGASNQ 598
Cdd:pfam03276  551 GQRW------GEGRGNRENENTENSEQRPREIQAGSGRPGNAGQGVKG----AAGQGGKGAAGRGGRGNGAGDQ 614
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 187-497 1.54e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.28  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  187 SKASSPATSSQGKKGQGAQNQ-AKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEgaQNQGKKGEGAQNQAKKGEGGQ 265
Cdd:NF012221 1540 SSQQADAVSKHAKQDDAAQNAlADKERAEADRQRLEQEKQQQLAAISGSQSQLESTD--QNALETNGQAQRDAILEESRA 1617

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  266 NQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKG--EGAQNQ---AKKGEGAQNQGKKGEGAQNQSKkgegAQNQAKK 340
Cdd:NF012221 1618 VTKELTTLAQGLDALDSQATYAGESGDQWRNPFAGGllDRVQEQlddAKKISGKQLADAKQRHVDNQQK----VKDAVAK 1693

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  341 GEGGQNQAKKGEgaQNQAKKGEGAQNQAKKGEgvQNQAKKGVEgAQNQGKKGEANQNQAKKGegGQNQTKKGEGPQNQGK 420
Cdd:NF012221 1694 SEAGVAQGEQNQ--ANAEQDIDDAKADAEKRK--DDALAKQNE-AQQAESDANAAANDAQSR--GEQDASAAENKANQAQ 1766

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  421 KGEAAQKQDKkiegaqnqGKKPEgtsNQGKKGEGAQNQGKKGEGAQNQG---KKGEGAQNQGKKGEGAQNQGKKG-EGAQ 496
Cdd:NF012221 1767 ADAKGAKQDE--------SDKPN---RQGAAGSGLSGKAYSVEGVAEPGshiNPDSPAAADGRFSEGLTEQEQEAlEGAT 1835


                  .
gi 568918950  497 N 497
Cdd:NF012221 1836 N 1836
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 400-593 7.42e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 40.66  E-value: 7.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  400 KKGEGGQNQTKKGEGPQN-QGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQnQGKKGEgAQNQGKKGEGAQNQ 478
Cdd:NF038329  118 EKGEPGPAGPAGPAGEQGpRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGP-AGKDGE-AGAKGPAGEKGPQG 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  479 GKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGE----GPQNQAKKGEGAQNQGKKGEGAQN--QGKKG 552
Cdd:NF038329  196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDpgptGEDGPQGPDGPAGKDGPRGDRGEAgpDGPDG 275

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 568918950  553 EGAQNQGKKAEGVQSQSKKGEGTQNQGKKG----DGNPnqGKKGE 593
Cdd:NF038329  276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGqngkDGLP--GKDGK 318
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 810-1422 8.73e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.29  E-value: 8.73e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   810 LVAREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLEnGPNTQLARLQQENSILRDALNQATSQVeSKQNTELAKL 889
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE-ELRLEVSELEEEIEELQKELYALANEI-SRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   890 RQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASH-----------------KESEEALQKRLEEVTRE 952
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELesleaeleeleaeleelESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   953 LCRAQTSHANLRADAEKAQEQQQRVAELHSKLQS--SEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQ 1030
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQeiEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1031 AQDTQASHA------EANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDL---------REKNWKAMEAlalaer 1095
Cdd:TIGR02168  468 EELEEAEQAldaaerELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvDEGYEAAIEA------ 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1096 ACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISA------HQNYAEWLQEFKEKGSELLKKPPTLEPSMD-- 1167
Cdd:TIGR02168  542 ALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSyl 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1168 -----IVLKLREAEETQNSLQAEcdqYRTILAE--------------TEGMLKDLQKSVEEEERvwKAKVGAAEEELHKS 1228
Cdd:TIGR02168  622 lggvlVVDDLDNALELAKKLRPG---YRIVTLDgdlvrpggvitggsAKTNSSILERRREIEEL--EEKIEELEEKIAEL 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1229 RVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDE 1308
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1309 LALLKTQLERTEATLEAEQTRRQKLTAEFEEAqrtacriQEELEKLRaagplessgkEEITQLKERLEKEKRLTSDLGRA 1388
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDEL-------RAELTLLN----------EEAANLRERLESLERRIAATERR 839

                          650       660       670
                   ....*....|....*....|....*....|....
gi 568918950  1389 AIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAED 1422
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEIEELEELIEELES 873
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 821-1412 2.01e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 2.01e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  821 QARMQASYRDHVKEVQQLQG-----KIRTLQEQLENGpNTQLARLQQENSILRDALNQATSQVESKQNtELAKLRQELSK 895
Cdd:COG1196   208 QAEKAERYRELKEELKELEAellllKLRELEAELEEL-EAELEELEAELEELEAELAELEAELEELRL-ELEELELELEE 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  896 VNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQ 975
Cdd:COG1196   286 AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  976 RVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQV 1055
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1056 ScLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERAcEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSI 1135
Cdd:COG1196   446 E-AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE-LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1136 SAHQNYAEWLQEFKEKGSELLkkpptLEPSMDIVLKLREAEETQNSLQAECDQYR-TILAETEGMLKDLQKSVEEEERVW 1214
Cdd:COG1196   524 GAVAVLIGVEAAYEAALEAAL-----AAALQNIVVEDDEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIG 598

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1215 KAKVGAAEEELHKSRVTVKHLEDIVEK--LKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQ 1292
Cdd:COG1196   599 AAVDLVASDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1293 SQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLR--------AAGPLESSG 1364
Cdd:COG1196   679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELleeeelleEEALEELPE 758

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568918950 1365 KEEITQLKERLEKEKRLTSDLGR---AAIKLQELLKTTQEQLTKEKDTVKK 1412
Cdd:COG1196   759 PPDLEELERELERLEREIEALGPvnlLAIEEYEELEERYDFLSEQREDLEE 809
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 910-1421 2.54e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.07  E-value: 2.54e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  910 EEQQRKALEAKAATFEKQVLQLQA------SHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSK 983
Cdd:COG1196   206 ERQAEKAERYRELKEELKELEAELlllklrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  984 LQSSEVEVKSKCEEL----SSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQAShAEANQQQTRLKELESQVSCLE 1059
Cdd:COG1196   286 AQAEEYELLAELARLeqdiARLEERRRELEERLEELEEELAELEEELEELEEELEELE-EELEEAEEELEEAEAELAEAE 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1060 KETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLH-LAEAQTKETLLALLPGLSISAH 1138
Cdd:COG1196   365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEeLEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1139 QNYAEWLQEFKEKGSELLKKpptlepsmdiVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKV 1218
Cdd:COG1196   445 EEAAEEEAELEEEEEALLEL----------LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1219 GAAEEELHKSRVTVkhLEDIVEKLKGELESSDQVREHTSHLEAElekhmaAASAECQNYAKEVAGLR----QLLLESQSQ 1294
Cdd:COG1196   515 LLAGLRGLAGAVAV--LIGVEAAYEAALEAALAAALQNIVVEDD------EVAAAAIEYLKAAKAGRatflPLDKIRARA 586

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1295 LDEAKSEAQKQSDELALLKTQLERTEATLEAEQTR---RQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEIT-Q 1370
Cdd:COG1196   587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTllgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgS 666

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568918950 1371 LKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAE 1421
Cdd:COG1196   667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 747-1357 3.96e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.22  E-value: 3.96e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  747 WHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQA 826
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  827 SYRdhvkEVQQLQGKIRTLQEQLENgpntqlarLQQENSILRDALNQATSQVESKQNtELAKLRQELSKVNKELVEKSEA 906
Cdd:COG1196   314 LEE----RLEELEEELAELEEELEE--------LEEELEELEEELEEAEEELEEAEA-ELAEAEEALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  907 SRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQS 986
Cdd:COG1196   381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  987 SEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELK 1066
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1067 EAMEQQKGKNNDLREknwkAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQNYAEWLQ 1146
Cdd:COG1196   541 EAALAAALQNIVVED----DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1147 EFkekGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAEcdqyRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELH 1226
Cdd:COG1196   617 VL---GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE----GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1227 KSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKqs 1306
Cdd:COG1196   690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER-- 767

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568918950 1307 dELALLKTQLERTEA-------TLEAEQTRRQKLTAEFEEaqrtacrIQEELEKLRAA 1357
Cdd:COG1196   768 -ELERLEREIEALGPvnllaieEYEELEERYDFLSEQRED-------LEEARETLEEA 817
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
828-1394 2.38e-14

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 78.42  E-value: 2.38e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  828 YRDHVKEVQQLQGKIRTLQEQLE--NGPNTQLARLQQENSILRDALNQATSQVESKQntELAKLRQELSKVN-----KEL 900
Cdd:COG4913   213 VREYMLEEPDTFEAADALVEHFDdlERAHEALEDAREQIELLEPIRELAERYAAARE--RLAELEYLRAALRlwfaqRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  901 VEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQ----KRLEEVTRELCRAQTSHANLRadaEKAQEQQQR 976
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRgnggDRLEQLEREIERLERELEERE---RRRARLEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  977 VAELHSKLQSSEvevkskcEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQashaEANQQQTRLKELESQVS 1056
Cdd:COG4913   368 LAALGLPLPASA-------EEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR----ELRELEAEIASLERRKS 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1057 CLEKETSELKEAMEqqkgknndlreknwkamEALALAER----ACEeklrsLTQAKEES-------EKQLH------LAE 1119
Cdd:COG4913   437 NIPARLLALRDALA-----------------EALGLDEAelpfVGE-----LIEVRPEEerwrgaiERVLGgfaltlLVP 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1120 AQTKETLLALLPGLSISAHQNYaewlqeFKEKGSELLKKPPTLEPSmDIVLKLrEAEET--QNSLQAEC-DQYRTILAET 1196
Cdd:COG4913   495 PEHYAAALRWVNRLHLRGRLVY------ERVRTGLPDPERPRLDPD-SLAGKL-DFKPHpfRAWLEAELgRRFDYVCVDS 566

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1197 EGMLKDLQKSVEEE------------------ERVW------KAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQV 1252
Cdd:COG4913   567 PEELRRHPRAITRAgqvkgngtrhekddrrriRSRYvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQER 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1253 REHTSHLE---------AELEKHMAAASAECQNYAKEVAGLRQLllesQSQLDEAKSEAQKQSDELALLKTQLERTEATL 1323
Cdd:COG4913   647 REALQRLAeyswdeidvASAEREIAELEAELERLDASSDDLAAL----EEQLEELEAELEELEEELDELKGEIGRLEKEL 722

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568918950 1324 EAEQTRRQKLTAEFEEAQRTACRIQ-EELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQE 1394
Cdd:COG4913   723 EQAEEELDELQDRLEAAEDLARLELrALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMR 794
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 760-1420 7.61e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 7.61e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   760 LKRQLEEKEK-LLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARM---QASYRDHVKEV 835
Cdd:TIGR02168  218 LKAELRELELaLLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIeelQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   836 QQLQGKIRTLQEQLEN------GPNTQLARLQQENSILRDALNQATSQVESKQN---------TELAKLRQELSKVNKEL 900
Cdd:TIGR02168  298 SRLEQQKQILRERLANlerqleELEAQLEELESKLDELAEELAELEEKLEELKEelesleaelEELEAELEELESRLEEL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   901 VEKSEASR----QEEQQRKALEAKAATFEKQVLQLQASHKESEE---------------ALQKRLEEVTRELCRAQTSHA 961
Cdd:TIGR02168  378 EEQLETLRskvaQLELQIASLNNEIERLEARLERLEDRRERLQQeieellkkleeaelkELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   962 NLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKC-------EELSSLHGQLKEARAENSQLT-------ERIR------- 1020
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLdslerlqENLEGFSEGVKALLKNQSGLSgilgvlsELISvdegyea 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1021 SIEALL-------------EAGQAQDTQASH------------------------------------------------- 1038
Cdd:TIGR02168  538 AIEAALggrlqavvvenlnAAKKAIAFLKQNelgrvtflpldsikgteiqgndreilkniegflgvakdlvkfdpklrka 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1039 --------------AEANQQQTRLKELESQVS------------------------CLEKETSELKEAMEQQKGKNNDLR 1080
Cdd:TIGR02168  618 lsyllggvlvvddlDNALELAKKLRPGYRIVTldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1081 eknwKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQNYAewLQEFKEKGSELLKKPP 1160
Cdd:TIGR02168  698 ----KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE--LTELEAEIEELEERLE 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1161 TLEPsmdivlKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEervwkakvgaaEEELHKSRVTVKHLEDIVE 1240
Cdd:TIGR02168  772 EAEE------ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL-----------NEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1241 KLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTE 1320
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1321 ATLEAEQTRRQKLTAEFEEAQRTACRIQEELEK-----LRAAGPLESSGKEEITQLKERLEKEKRLTSDLGR---AAIKL 1392
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRIDNLQERLSEeysltLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnlAAIEE 994

                          810       820
                   ....*....|....*....|....*...
gi 568918950  1393 QELLKTTQEQLTKEKDTVKKLQEQLGKA 1420
Cdd:TIGR02168  995 YEELKERYDFLTAQKEDLTEAKETLEEA 1022
PTZ00121 PTZ00121
MAEBL; Provisional
 861-1428 1.25e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 76.33  E-value: 1.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  861 QQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKElVEKSEASRQEEQQRKALEAKAATFEKQV-----LQLQASH 935
Cdd:PTZ00121 1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEE-ARKAEDARKAEEARKAEDAKRVEIARKAedarkAEEARKA 1172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  936 KESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKeaRAENSQL 1015
Cdd:PTZ00121 1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAK--KAEEERN 1250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1016 TERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLR---EKNWKAMEALAL 1092
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKkadEAKKKAEEAKKK 1330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1093 AERA---CEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIV 1169
Cdd:PTZ00121 1331 ADAAkkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL 1410

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1170 LKLREAEETQNSLQAECDQYRTI------------------LAETEGMLKDLQKSVEEEERVWKAKVGAAE----EELHK 1227
Cdd:PTZ00121 1411 KKAAAAKKKADEAKKKAEEKKKAdeakkkaeeakkadeakkKAEEAKKAEEAKKKAEEAKKADEAKKKAEEakkaDEAKK 1490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1228 SRVTVKHLEDIVEKLKGELESSDQVREHTSHLEA-ELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQS 1306
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAdEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1307 DELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACR--IQEELEKLRAAG-PLESSGKEEITQLKERLEKEKRLTS 1383
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEeaKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAE 1650

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568918950 1384 DLGRA----AIKLQELLKTTQE------QLTKEKDTVKKLQEQLGKAEDGSSSKE 1428
Cdd:PTZ00121 1651 ELKKAeeenKIKAAEEAKKAEEdkkkaeEAKKAEEDEKKAAEALKKEAEEAKKAE 1705
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
827-1395 3.89e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 74.33  E-value: 3.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  827 SYRDHVKEVQQLQGKIRTLQEQLEngpntqlaRLQQENSILRDALNQATSQVEskqntELAKLRQELSKVNKELVEKSEA 906
Cdd:PRK03918  180 RLEKFIKRTENIEELIKEKEKELE--------EVLREINEISSELPELREELE-----KLEKEVKELEELKEEIEELEKE 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  907 SRQEEQQRKALEAKAATFEKQVLQLqashKESEEALQKRLEEVTrELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQS 986
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEERIEEL----KKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  987 SEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAgqAQDTQASHAEANQQQTRLK-----ELESQVSCLEKE 1061
Cdd:PRK03918  322 EINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHEL--YEEAKAKKEELERLKKRLTgltpeKLEKELEELEKA 399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1062 TSELKEAMEQQKGKNNDLREKN---WKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLpglsisah 1138
Cdd:PRK03918  400 KEEIEEEISKITARIGELKKEIkelKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEI-------- 471

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1139 QNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNS-----LQAECDQYRTI---LAETEGMLKDLQKSVEEE 1210
Cdd:PRK03918  472 EEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKynleeLEKKAEEYEKLkekLIKLKGEIKSLKKELEKL 551

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1211 ERVwKAKVGAAEEELHKSRVTVKHLEDIVEKLKgeLESSDQVREHTSHLEAELEKHMAAASAEcqnyakevaglrQLLLE 1290
Cdd:PRK03918  552 EEL-KKKLAELEKKLDELEEELAELLKELEELG--FESVEELEERLKELEPFYNEYLELKDAE------------KELER 616

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1291 SQSQLDEAKSEAQKQSDELALLKTQLERTEATLEA-----EQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGK 1365
Cdd:PRK03918  617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEElekkySEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTL 696

                         570       580       590
                  ....*....|....*....|....*....|
gi 568918950 1366 EEITQLKERLEKEKRLTSDLGRAAIKLQEL 1395
Cdd:PRK03918  697 EKLKEELEEREKAKKELEKLEKALERVEEL 726
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
874-1422 8.15e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 73.56  E-value: 8.15e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  874 ATSQVESKQNTELAKLRQELSKVNKElVEKSEASRQE----EQQRKALEAKAATFEKQVLQLQASHKESEEALqKRLEEV 949
Cdd:PRK03918  204 EVLREINEISSELPELREELEKLEKE-VKELEELKEEieelEKELESLEGSKRKLEEKIRELEERIEELKKEI-EELEEK 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  950 TRELCRAQ---TSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALL 1026
Cdd:PRK03918  282 VKELKELKekaEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERH 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1027 EAgqAQDTQASHAEANQQQTRLK-----ELESQVSCLEKETSELKEAMEQQKGKNNDLREKNW---KAMEALALAERACE 1098
Cdd:PRK03918  362 EL--YEEAKAKKEELERLKKRLTgltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKelkKAIEELKKAKGKCP 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1099 EKLRSLTQakeesEKQLHLAEAQTKETllallpglsisahQNYAEWLQEFKEKGSELLKKPPTLEpsmdivlKLREAEET 1178
Cdd:PRK03918  440 VCGRELTE-----EHRKELLEEYTAEL-------------KRIEKELKEIEEKERKLRKELRELE-------KVLKKESE 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1179 QNSLQAECDQYRTILAETEGM-LKDLQKSVEEEERVwKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTS 1257
Cdd:PRK03918  495 LIKLKELAEQLKELEEKLKKYnLEELEKKAEEYEKL-KEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELA 573

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1258 HLEAELEKHMAAASAECQNYAKEVAGLRQLLLEsqsqLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEF 1337
Cdd:PRK03918  574 ELLKELEELGFESVEELEERLKELEPFYNEYLE----LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKEL 649

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1338 EEAQRTACriQEELEKLRAagpLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLkttqEQLTKEKDTVKKLQEQL 1417
Cdd:PRK03918  650 EELEKKYS--EEEYEELRE---EYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKAL 720


                  ....*
gi 568918950 1418 GKAED 1422
Cdd:PRK03918  721 ERVEE 725
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 260-513 3.44e-12

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 71.57  E-value: 3.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   260 KGEGGQNQAKkGEGAQNQGKKGEGAQnqGKKGEGAQNQAKKGEGAQNQAK-KGEGAQNQGKKGEGAQNQSKKGEGAQNqa 338
Cdd:TIGR00927  632 KGDVAEAEHT-GERTGEEGERPTEAE--GENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH-- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   339 kKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQ 418
Cdd:TIGR00927  707 -KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQA 785

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   419 GK----KGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQ-GKKGEGAQNQGKKGE 493
Cdd:TIGR00927  786 GEdgemKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEkGVDGGGGSDGGDSEE 865

                          250       260
                   ....*....|....*....|
gi 568918950   494 GAQNQGKKGEGAQNQGKKGE 513
Cdd:TIGR00927  866 EEEEEEEEEEEEEEEEEEEE 885
PTZ00121 PTZ00121
MAEBL; Provisional
 757-1432 4.27e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 71.33  E-value: 4.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  757 VAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQ 836
Cdd:PTZ00121 1154 VEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAE 1233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  837 QLQGKIRTLQeQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNK-----ELVEKSEASRQEE 911
Cdd:PTZ00121 1234 EAKKDAEEAK-KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEakkaeEKKKADEAKKKAE 1312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  912 QQRKALEAK--AATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEV 989
Cdd:PTZ00121 1313 EAKKADEAKkkAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  990 --EVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKElESQVSCLEKETSELKE 1067
Cdd:PTZ00121 1393 adEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEE-AKKAEEAKKKAEEAKK 1471

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1068 AME-----QQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQlhlAEAQTKETLLALLPGLSISAHQNYA 1142
Cdd:PTZ00121 1472 ADEakkkaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK---ADEAKKAEEAKKADEAKKAEEKKKA 1548

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1143 EWLQEFKE--KGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTiLAETEGMLKDLQKSVEEEERVWKAKVGA 1220
Cdd:PTZ00121 1549 DELKKAEElkKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK-LYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1221 AEEELhksrvtvKHLEDIVEKLKGELESSDQVREHTSHLEAELEKhMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKS 1300
Cdd:PTZ00121 1628 AEEEK-------KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE-EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE 1699

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1301 EAQKQSDELALLKTQLERTEATLEAEQTRRQKLtaefEEAQRTACRIQEELEKLRaagpLESSGKEEITQLKERLEKEKR 1380
Cdd:PTZ00121 1700 EAKKAEELKKKEAEEKKKAEELKKAEEENKIKA----EEAKKEAEEDKKKAEEAK----KDEEEKKKIAHLKKEEEKKAE 1771

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|..
gi 568918950 1381 LTSDLGRAAIKlQELLKTTQEQLTKEKDTVKKLQEQLGKAEDGssSKEGTSV 1432
Cdd:PTZ00121 1772 EIRKEKEAVIE-EELDEEDEKRRMEVDKKIKDIFDNFANIIEG--GKEGNLV 1820
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
868-1416 5.61e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.84  E-value: 5.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  868 RDALNQATSQVESKQNTE----LAKLRQELSKVNKELVEKSEasrQEEQQRKALEAKAATFEkqvlqlqaSHKESEEALQ 943
Cdd:PRK02224  186 RGSLDQLKAQIEEKEEKDlherLNGLESELAELDEEIERYEE---QREQARETRDEADEVLE--------EHEERREELE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  944 kRLEEVTRELCRAQTSHANLRAD-AEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRsi 1022
Cdd:PRK02224  255 -TLEAEIEDLRETIAETEREREElAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE-- 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1023 EALLEAGQAQDTQASHAE-ANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEkL 1101
Cdd:PRK02224  332 ECRVAAQAHNEEAESLREdADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGN-A 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1102 RSLTQAKEESEKQLHLAEAQTKETLlallpglsisahqnyaEWLQEFKEKGSELLK--KPPTLEPSMD---IVLKLREAE 1176
Cdd:PRK02224  411 EDFLEELREERDELREREAELEATL----------------RTARERVEEAEALLEagKCPECGQPVEgspHVETIEEDR 474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1177 ETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVwkakvgaaEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHT 1256
Cdd:PRK02224  475 ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRI--------ERLEERREDLEELIAERRETIEEKRERAEELRERA 546

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1257 SHLEAELEKHMAAASaecqnyakevaglrqlllesqsqldeaksEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAE 1336
Cdd:PRK02224  547 AELEAEAEEKREAAA-----------------------------EAEEEAEEAREEVAELNSKLAELKERIESLERIRTL 597

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1337 FEEAQRTACRIQEELEKLRAAGPLESSGKEeitQLKERLEKEKRLTSDLGRAAI-KLQELLKTTQEQLTKEKDTVKKLQE 1415
Cdd:PRK02224  598 LAAIADAEDEIERLREKREALAELNDERRE---RLAEKRERKRELEAEFDEARIeEAREDKERAEEYLEQVEEKLDELRE 674


                  .
gi 568918950 1416 Q 1416
Cdd:PRK02224  675 E 675
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 310-576 6.72e-12

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 70.41  E-value: 6.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   310 KGEGAQNQgKKGEGAQNQSKKGEGAQnqAKKGEGGQNQAKKGEGAQNqakKGEGAQNQAKKGEGVQNQAKKGVEGAQNQG 389
Cdd:TIGR00927  632 KGDVAEAE-HTGERTGEEGERPTEAE--GENGEESGGEAEQEGETET---KGENESEGEIPAERKGEQEGEGEIEAKEAD 705

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   390 KKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDK-KIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGaqnQ 468
Cdd:TIGR00927  706 HKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEgEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEG---E 782

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   469 GKKGEGAQNQGKKGE--GAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQ 546
Cdd:TIGR00927  783 IQAGEDGEMKGDEGAegKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGD 862

                          250       260       270
                   ....*....|....*....|....*....|
gi 568918950   547 NQGKKGEGAQNQGKKAEGVQSQSKKGEGTQ 576
Cdd:TIGR00927  863 SEEEEEEEEEEEEEEEEEEEEEEEEEENEE 892
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 360-593 8.10e-12

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 70.41  E-value: 8.10e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   360 KGEGAQNQAKkGEGVQNQAKKGVEGaqnQGKKGEANQNQAKKGEGGQNQTK-KGEGPQNQGKKGEAAQKQDKKIEGAQNQ 438
Cdd:TIGR00927  632 KGDVAEAEHT-GERTGEEGERPTEA---EGENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADHK 707

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   439 GKKPEGtsnQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGK-KGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQN 517
Cdd:TIGR00927  708 GETEAE---EVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEgEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQ 784

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568918950   518 QGKKGE--GPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGE 593
Cdd:TIGR00927  785 AGEDGEmkGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGD 862
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 192-443 9.44e-12

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 70.02  E-value: 9.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   192 PATSSQGKKGQGAQNQAKKGEGAQNQGK-KGEGAQNQAKKGEGAQNQAKKGEGAQNqgkKGEGAQNQAKKGEGGQNQAKK 270
Cdd:TIGR00927  651 RPTEAEGENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH---KGETEAEEVEHEGETEAEGTE 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   271 GEGAQNQGKKGEGAQNQGK-KGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGaqnQSKKGEGAQNQAKKGEGGQNQAK 349
Cdd:TIGR00927  728 DEGEIETGEEGEEVEDEGEgEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEG---EIQAGEDGEMKGDEGAEGKVEHE 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   350 KGEGAQNQAKKGEGAQNQAKKGEGvqnqakKGVEGAQNQGKKgeaNQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQD 429
Cdd:TIGR00927  805 GETEAGEKDEHEGQSETQADDTEV------KDETGEQELNAE---NQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEE 875

                          250
                   ....*....|....
gi 568918950   430 KKIEGAQNQGKKPE 443
Cdd:TIGR00927  876 EEEEEEEEEEEEEE 889
PTZ00121 PTZ00121
MAEBL; Provisional
 188-685 9.67e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 70.17  E-value: 9.67e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  188 KASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNqgKKGEGAQNQAKKGEGGQNQ 267
Cdd:PTZ00121 1291 KADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAK--AEAEAAADEAEAAEEKAEA 1368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  268 AKKGEgaQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEggqnQ 347
Cdd:PTZ00121 1369 AEKKK--EEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE----E 1442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  348 AKKGEGAQNQAKKGEGAQNQAKKGEgvqnqAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQK 427
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEAKKKAE-----EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKK 1517

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  428 QDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKgegAQNQGKKGEGAQN 507
Cdd:PTZ00121 1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALR---KAEEAKKAEEARI 1594

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  508 QGKKGEGAQNQGKKGEgpqnQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQG----KKAEGVQSQSKKGEGTQNQ-GKKG 582
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAE----EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEaeekKKAEELKKAEEENKIKAAEeAKKA 1670

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  583 DGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSpnQGKKAEGAPNQGKKKDGSPSQAKKvDAAANQGKKS 662
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAE--EKKKAEELKKAEEENKIKAEEAKK-EAEEDKKKAE 1747

                         490       500
                  ....*....|....*....|...
gi 568918950  663 EMAPAQGQKASMVQSQEAPKQDA 685
Cdd:PTZ00121 1748 EAKKDEEEKKKIAHLKKEEEKKA 1770
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
914-1425 3.36e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 68.40  E-value: 3.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  914 RKALEAKAATFEKQVLQLQASHKESEEALQKR--LEEvtrelcraqtshanLRADAEKAQEQQQRVAELHSKLQSSEVEV 991
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERAHEALEDAREQIelLEP--------------IRELAERYAAARERLAELEYLRAALRLWF 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  992 KSKCEELssLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQ 1071
Cdd:COG4913   286 AQRRLEL--LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRAR 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1072 QKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQ------TKETLLALLPGLSiSAHQNYAEWL 1145
Cdd:COG4913   364 LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAAlrdlrrELRELEAEIASLE-RRKSNIPARL 442

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1146 QEFKEKGSELLKKPPTlepSMDIV---LKLREAEET-QNSL------QAecdqyRTILAEtEGMLKDLQKSVEE---EER 1212
Cdd:COG4913   443 LALRDALAEALGLDEA---ELPFVgelIEVRPEEERwRGAIervlggFA-----LTLLVP-PEHYAAALRWVNRlhlRGR 513

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1213 VWKAKVGAAEEELHKSRVTVKHLediVEKLK-------GELEssDQVREHTSHL----EAELEKHMAAASAECQNYAKEV 1281
Cdd:COG4913   514 LVYERVRTGLPDPERPRLDPDSL---AGKLDfkphpfrAWLE--AELGRRFDYVcvdsPEELRRHPRAITRAGQVKGNGT 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1282 AG--------LRQLLL--ESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTA---------EFEEAQR 1342
Cdd:COG4913   589 RHekddrrriRSRYVLgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAER 668

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1343 TACRIQEELEKLRAAGPlessgkeEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAED 1422
Cdd:COG4913   669 EIAELEAELERLDASSD-------DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED 741


                  ...
gi 568918950 1423 GSS 1425
Cdd:COG4913   742 LAR 744
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
922-1407 4.94e-11

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 67.49  E-value: 4.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  922 ATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQS--SEVEVKSKCEELS 999
Cdd:COG4717    49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEElrEELEKLEKLLQLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1000 SLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRlkelESQVSCLEKETSELKEAMEQQKGKNNDL 1079
Cdd:COG4717   129 PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQ----EELEELLEQLSLATEEELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1080 REKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQnyaewlqefkekGSELLKKP 1159
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGL------------GGSLLSLI 272

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1160 PTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQksvEEEERVWKAKVGAAEEElhkSRVTVKHLEDIV 1239
Cdd:COG4717   273 LTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELE---EEELEELLAALGLPPDL---SPEELLELLDRI 346

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1240 EKLKGELESSDQVREH--TSHLEAELEKHMAAASAE-------CQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSD--E 1308
Cdd:COG4717   347 EELQELLREAEELEEElqLEELEQEIAALLAEAGVEdeeelraALEQAEEYQELKEELEELEEQLEELLGELEELLEalD 426

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1309 LALLKTQLERTEATLEAEQTRRQKLTAEFEEaqrtacrIQEELEKLRAAGPLessgkEEITQLKERLEKEKRLTSDLGRA 1388
Cdd:COG4717   427 EEELEEELEELEEELEELEEELEELREELAE-------LEAELEQLEEDGEL-----AELLQELEELKAELRELAEEWAA 494

                         490
                  ....*....|....*....
gi 568918950 1389 AIKLQELLKTTQEQLTKEK 1407
Cdd:COG4717   495 LKLALELLEEAREEYREER 513
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1171-1426 4.98e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 4.98e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1171 KLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEE---EERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELE 1247
Cdd:COG1196   247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1248 SSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLES-------QSQLDEAKSEAQKQSDELALLKTQLERTE 1320
Cdd:COG1196   327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAeaelaeaEEELEELAEELLEALRAAAELAAQLEELE 406

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1321 ATLEAEQTRRQKLTAEFEEAQRtacRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQ 1400
Cdd:COG1196   407 EAEEALLERLERLEEELEELEE---ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                         250       260
                  ....*....|....*....|....*.
gi 568918950 1401 EQLTKEKDTVKKLQEQLGKAEDGSSS 1426
Cdd:COG1196   484 EELAEAAARLLLLLEAEADYEGFLEG 509
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
785-1259 9.07e-11

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 66.33  E-value: 9.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  785 LRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARmQASYRDHVKEVQQLQGKIRTLQEQLENgPNTQLARLQQEN 864
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEK-EEEYAELQEELEELEEELEELEAELEE-LREELEKLEKLL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  865 SILRDA--LNQATSQVESKQnTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEAL 942
Cdd:COG4717   126 QLLPLYqeLEALEAELAELP-ERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  943 QKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELhsklqssevEVKSKCEELSSLHGQLKEARAENSQLTERIRSI 1022
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALE---------ERLKEARLLLLIAAALLALLGLGGSLLSLILTI 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1023 EAL------LEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERA 1096
Cdd:COG4717   276 AGVlflvlgLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLRE 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1097 CEEKLRSLTQAKEESEKQ--LHLAEAQTKETLLALLpglsiSAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIV----- 1169
Cdd:COG4717   356 AEELEEELQLEELEQEIAalLAEAGVEDEEELRAAL-----EQAEEYQELKEELEELEEQLEELLGELEELLEALdeeel 430

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1170 -LKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVE------EEERVwKAKVGAAEEELHKSRVTVKHLEDIVEKL 1242
Cdd:COG4717   431 eEELEELEEELEELEEELEELREELAELEAELEQLEEDGElaellqELEEL-KAELRELAEEWAALKLALELLEEAREEY 509

                         490
                  ....*....|....*..
gi 568918950 1243 kgELESSDQVREHTSHL 1259
Cdd:COG4717   510 --REERLPPVLERASEY 524
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 220-503 9.36e-11

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 66.94  E-value: 9.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   220 KGEGAQNQAKkGEGAQNQAKKGEGAQnqGKKGEGAQNQAKKGEGGQNQAK-KGEGAQNQGKKGEGAQNQGKKGEGAQNqa 298
Cdd:TIGR00927  632 KGDVAEAEHT-GERTGEEGERPTEAE--GENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH-- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   299 kKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEgaqnqaKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGvqnqa 378
Cdd:TIGR00927  707 -KGETEAEEVEHEGETEAEGTEDEGEIETGEEGE------EVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEG----- 774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   379 kkgvEGAQNQGkkgeanqnQAKKGEGGQNqtkKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQ 458
Cdd:TIGR00927  775 ----KEDEDEG--------EIQAGEDGEM---KGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNA 839

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 568918950   459 GKKGEGAQNQ-GKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGE 503
Cdd:TIGR00927  840 ENQGEAKQDEkGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEE 885
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 829-1417 1.23e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 66.40  E-value: 1.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   829 RDHVKEVQQLQGKIRTLQEQLENgPNTQLARLQQENSILRDALNQATSQVESKQnTELAKLRQELSKVNKELVEKSEASR 908
Cdd:pfam12128  230 IQAIAGIMKIRPEFTKLQQEFNT-LESAELRLSHLHFGYKSDETLIASRQEERQ-ETSAELNQLLRTLDDQWKEKRDELN 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   909 QE-----------EQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEK-----AQE 972
Cdd:pfam12128  308 GElsaadaavakdRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRrrskiKEQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   973 QQQRVAELHSKLQSS-EVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEA------GQAQDTQASHAEANQQQ 1045
Cdd:pfam12128  388 NNRDIAGIKDKLAKIrEARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSrlgelkLRLNQATATPELLLQLE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1046 TRLKELESQVSCLEKETSELKEAMEQQKgknnDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHlaeaqtkeT 1125
Cdd:pfam12128  468 NFDERIERAREEQEAANAEVERLQSELR----QARKRRDQASEALRQASRRLEERQSALDELELQLFPQAG--------T 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1126 LLALLpglsisaHQNYAEWLQEF-KEKGSELLKKpPTLEPSMDIV----------LKLREAEETQNSLQAECDQYRTILA 1194
Cdd:pfam12128  536 LLHFL-------RKEAPDWEQSIgKVISPELLHR-TDLDPEVWDGsvggelnlygVKLDLKRIDVPEWAASEEELRERLD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1195 ETEGML---KDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELES------------SDQVREHTSHL 1259
Cdd:pfam12128  608 KAEEALqsaREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSekdkknkalaerKDSANERLNSL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1260 EAELE----KHMAA----------ASAECQNYAKEVAGLRQLLLesqSQLDEAKSEAQKQSD-ELALLKTQLERTEATLE 1324
Cdd:pfam12128  688 EAQLKqldkKHQAWleeqkeqkreARTEKQAYWQVVEGALDAQL---ALLKAAIAARRSGAKaELKALETWYKRDLASLG 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1325 AEQTRRQKLTAEFEEAQRTACRI-QEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQL 1403
Cdd:pfam12128  765 VDPDVIAKLKREIRTLERKIERIaVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKL 844

                          650
                   ....*....|....
gi 568918950  1404 TKEKDTVKKLQEQL 1417
Cdd:pfam12128  845 EMERKASEKQQVRL 858
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 378-597 1.30e-10

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 66.17  E-value: 1.30e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   378 AKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEgAQNQGKKPEGTSNQGK----KGE 453
Cdd:TIGR00927  631 SKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIP-AERKGEQEGEGEIEAKeadhKGE 709

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   454 GAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGK-KGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEG----PQNQ 528
Cdd:TIGR00927  710 TEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEgEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGeiqaGEDG 789

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   529 AKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDG-NPNQGKKGEGASN 597
Cdd:TIGR00927  790 EMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAkQDEKGVDGGGGSD 859
PTZ00121 PTZ00121
MAEBL; Provisional
 204-698 1.36e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 1.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  204 AQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKkgegAQNQGKKGEG 283
Cdd:PTZ00121 1208 AEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK----AEEARKADEL 1283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  284 AQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQnqAKKGEG 363
Cdd:PTZ00121 1284 KKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAA--ADEAEA 1361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  364 AQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPE 443
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE 1441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  444 gtsnQGKKGEGAQNQGKKGEGAQNQGKKGEgaqnQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGE 523
Cdd:PTZ00121 1442 ----EAKKADEAKKKAEEAKKAEEAKKKAE----EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKAD 1513

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  524 GPQN--QAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRK 601
Cdd:PTZ00121 1514 EAKKaeEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  602 TDTVANQGTKQEGV-SNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEA 680
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMkAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                         490
                  ....*....|....*...
gi 568918950  681 PKQDAPAKKKSGSRKKGE 698
Cdd:PTZ00121 1674 KKKAEEAKKAEEDEKKAA 1691
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
 33-168 2.40e-10

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 60.14  E-value: 2.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950    33 MKETSYEEALANQRKEMAKTHhQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKE---PVRVSAVAVAP 109
Cdd:pfam05104    1 MKETSYEEALAKQRRELKKTP-TEKEKKKKEKKKEKKKKSKKKEEKPNGKLPESEQADESEEEPREfktPDEAPSAALEP 79

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568918950   110 TSVhSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSA 168
Cdd:pfam05104   80 EPV-PTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPAETPEAVQPKPALEKEE 137
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 757-1422 3.27e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 3.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   757 VAILKRQLE--EKEKLLATEQEDAavaKSKLRELN-KEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQ---ASYRD 830
Cdd:TIGR02169  193 IDEKRQQLErlRREREKAERYQAL---LKEKREYEgYELLKEKEALERQKEAIERQLASLEEELEKLTEEISeleKRLEE 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   831 HVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNtELAKLRQELSKVnKELVEKSEASRQE 910
Cdd:TIGR02169  270 IEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE-RLAKLEAEIDKL-LAEIEELEREIEE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   911 EQQRKA-----LEAKAATFEKQVLQLQASHKESEE------ALQKRLEEVTRELCRAQTshaNLRADAEKAQEQQQRVAE 979
Cdd:TIGR02169  348 ERKRRDklteeYAELKEELEDLRAELEEVDKEFAEtrdelkDYREKLEKLKREINELKR---ELDRLQEELQRLSEELAD 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   980 LHSKLQSSEvevkskcEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQAShAEANQQQTRLKELESQVSCLE 1059
Cdd:TIGR02169  425 LNAAIAGIE-------AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK-EEYDRVEKELSKLQRELAEAE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1060 KETSELKE------AMEQQKGKNND-----------LREKNWKAMEALALA---------ERACEEKLRSLTQAKEESEK 1113
Cdd:TIGR02169  497 AQARASEErvrggrAVEEVLKASIQgvhgtvaqlgsVGERYATAIEVAAGNrlnnvvvedDAVAKEAIELLKRRKAGRAT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1114 QLHLAEAQTKETLL-ALLPGLSISAHQNYAEWLQEFK----------------EKGSELLKK-------PPTLEPSMDIV 1169
Cdd:TIGR02169  577 FLPLNKMRDERRDLsILSEDGVIGFAVDLVEFDPKYEpafkyvfgdtlvvediEAARRLMGKyrmvtleGELFEKSGAMT 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1170 ---LKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERV---WKAKVGAAEEELHKSRVTVKHLEDIVEKLK 1243
Cdd:TIGR02169  657 ggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRldeLSQELSDASRKIGEIEKEIEQLEQEEEKLK 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1244 GELESS-------DQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLleSQSQLDEAKSEAQKQSDELALLKTQL 1316
Cdd:TIGR02169  737 ERLEELeedlsslEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL--SHSRIPEIQAELSKLEEEVSRIEARL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1317 ERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAgplESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELL 1396
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE---IENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891

                          730       740
                   ....*....|....*....|....*.
gi 568918950  1397 KTTQEQLTKEKDTVKKLQEQLGKAED 1422
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQIEKKRK 917
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 290-556 3.82e-10

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 64.63  E-value: 3.82e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   290 KGEGAQNQAKkGEGAQNQAKKGEGAQnqGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQA-KKGEGAQNQAKKGEGAQNQA 368
Cdd:TIGR00927  632 KGDVAEAEHT-GERTGEEGERPTEAE--GENGEESGGEAEQEGETETKGENESEGEIPAeRKGEQEGEGEIEAKEADHKG 708

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   369 KKGEG-VQNQAKKGVEGAQNQGKkgeaNQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGtsn 447
Cdd:TIGR00927  709 ETEAEeVEHEGETEAEGTEDEGE----IETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEG--- 781

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   448 QGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQG--KKGEGAQNQGKKGEGP 525
Cdd:TIGR00927  782 EIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGeaKQDEKGVDGGGGSDGG 861

                          250       260       270
                   ....*....|....*....|....*....|.
gi 568918950   526 QNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQ 556
Cdd:TIGR00927  862 DSEEEEEEEEEEEEEEEEEEEEEEEEEENEE 892
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
814-1376 4.34e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 64.68  E-value: 4.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  814 EQEIAAVQARMQA-----SYRDHVKEVQQLQGKIRTLQEQLengpntqlARLQQENSILRDALNQATSQVEskqntelak 888
Cdd:PRK02224  227 EQREQARETRDEAdevleEHEERREELETLEAEIEDLRETI--------AETEREREELAEEVRDLRERLE--------- 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  889 lrqELSKVNKELVEKSEAsrqEEQQRKALEAKAATFEKQvlqlqashkesEEALQKRLEEVTRELCRAQTSHANLRADA- 967
Cdd:PRK02224  290 ---ELEEERDDLLAEAGL---DDADAEAVEARREELEDR-----------DEELRDRLEECRVAAQAHNEEAESLREDAd 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  968 ---EKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEagqaqDTQASHAEANQq 1044
Cdd:PRK02224  353 dleERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLE-----ELREERDELRE- 426

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1045 qtRLKELEsqvscleketSELKEAmeqqkgkNNDLREKnwkamEALaLAERACEEklrsLTQAKEESEKQLHLAEA-QTK 1123
Cdd:PRK02224  427 --REAELE----------ATLRTA-------RERVEEA-----EAL-LEAGKCPE----CGQPVEGSPHVETIEEDrERV 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1124 ETLlallpglsisahqnyAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDL 1203
Cdd:PRK02224  478 EEL---------------EAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEEL 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1204 QKSVEE---EERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEaelekhmaaasaecqNYAKE 1280
Cdd:PRK02224  543 RERAAEleaEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIA---------------DAEDE 607

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1281 VAGLRqlllESQSQLDEAKSEAQKQSDELALLKTQLERT--EATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAA- 1357
Cdd:PRK02224  608 IERLR----EKREALAELNDERRERLAEKRERKRELEAEfdEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEi 683

                         570
                  ....*....|....*....
gi 568918950 1358 GPLESSgKEEITQLKERLE 1376
Cdd:PRK02224  684 GAVENE-LEELEELRERRE 701
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 760-1356 1.24e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 63.32  E-value: 1.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   760 LKRQLEEKEKLLATEQEDAAVA----KSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEV 835
Cdd:pfam12128  263 LHFGYKSDETLIASRQEERQETsaelNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETA 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   836 QQLQGKIRTLQEQLENGPNTQLARLQQENSILRdALNQATSQVESKQNTELAKLRQELSKVnkelveKSEASRQEEQQRK 915
Cdd:pfam12128  343 AADQEQLPSWQSELENLEERLKALTGKHQDVTA-KYNRRRSKIKEQNNRDIAGIKDKLAKI------REARDRQLAVAED 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   916 ALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQ------TSHANLRADAEKAQEQQQRVAELHSKLQSSEV 989
Cdd:pfam12128  416 DLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATatpellLQLENFDERIERAREEQEAANAEVERLQSELR 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   990 EVKSKCEELSSLHGQlkearaENSQLTERIRSIEALLEAGQAQDTQASHAEANQ----QQTRLKELESQVSCLEKETSEL 1065
Cdd:pfam12128  496 QARKRRDQASEALRQ------ASRRLEERQSALDELELQLFPQAGTLLHFLRKEapdwEQSIGKVISPELLHRTDLDPEV 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1066 KEAMEQQK----GKNNDLRE---KNWKAMEALALAERA-CEEKLRSLTQAKEESEKQLHLAEAQTKETLLALlpGLSISA 1137
Cdd:pfam12128  570 WDGSVGGElnlyGVKLDLKRidvPEWAASEEELRERLDkAEEALQSAREKQAAAEEQLVQANGELEKASREE--TFARTA 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1138 HQNYAEWLQE-FKEKGSELLKKPPTLEPSMDIVLKLREAEETQ-----NSLQAECDQYRTILAETEGMLKDLQKSVEEEE 1211
Cdd:pfam12128  648 LKNARLDLRRlFDEKQSEKDKKNKALAERKDSANERLNSLEAQlkqldKKHQAWLEEQKEQKREARTEKQAYWQVVEGAL 727

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1212 rvwKAKVGAAEEELHKSRVTVK-HLEDIVEKLKGELESSDQVREHTSHLEAELEKhMAAASAECQNYAKEVAGLRQLLLE 1290
Cdd:pfam12128  728 ---DAQLALLKAAIAARRSGAKaELKALETWYKRDLASLGVDPDVIAKLKREIRT-LERKIERIAVRRQEVLRYFDWYQE 803

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568918950  1291 S-QSQLDEAKSEAQKQSDELALLKTQLERTEATLEaeqTRRQKLTAEFEEAQRTACRIQEELEKLRA 1356
Cdd:pfam12128  804 TwLQRRPRLATQLSNIERAISELQQQLARLIADTK---LRRAKLEMERKASEKQQVRLSENLRGLRC 867
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 970-1344 1.50e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 1.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   970 AQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAqdtqashaEANQQQTRLK 1049
Cdd:TIGR02169  669 SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ--------EEEKLKERLE 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1050 ELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALA-LAERACEEKLRSLTQAKEESEKQLHLAEAQTKEtlla 1128
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNdLEARLSHSRIPEIQAELSKLEEEVSRIEARLRE---- 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1129 llpglsISAHQNYAEWLQEFKEKGSELLKkpptlEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKS-- 1206
Cdd:TIGR02169  817 ------IEQKLNRLTLEKEYLEKEIQELQ-----EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRlg 885

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1207 -VEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELES-SDQVREHTSHLEAELEKHMAAASAEcqnyakEVAGL 1284
Cdd:TIGR02169  886 dLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEAlEEELSEIEDPKGEDEEIPEEELSLE------DVQAE 959

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1285 RQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTA 1344
Cdd:TIGR02169  960 LQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
968-1422 2.51e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 61.98  E-value: 2.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  968 EKAQEQQQRVAELHSKLQSSEVEVKSKCEELSS--LHGQLKEARAENSQLTERIRSIEALLEA-----GQAQDTQASHAE 1040
Cdd:PRK02224  169 ERASDARLGVERVLSDQRGSLDQLKAQIEEKEEkdLHERLNGLESELAELDEEIERYEEQREQaretrDEADEVLEEHEE 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1041 ANQQQTRLK----ELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEeklrSLTQAKEESEKQlh 1116
Cdd:PRK02224  249 RREELETLEaeieDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAE----AVEARREELEDR-- 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1117 laEAQTKETLLALlpGLSISAHQNYAEWLQEfkekgsellkKPPTLEPSMDivlklrEAEETQNSLQAECDQYRTILAET 1196
Cdd:PRK02224  323 --DEELRDRLEEC--RVAAQAHNEEAESLRE----------DADDLEERAE------ELREEAAELESELEEAREAVEDR 382

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1197 EGMLKDLQKSVEEEErvwkAKVGAAEEELHKsrvtvkhLEDIVEKLkgeLESSDQVREHTSHLEAELekhmaaasaecQN 1276
Cdd:PRK02224  383 REEIEELEEEIEELR----ERFGDAPVDLGN-------AEDFLEEL---REERDELREREAELEATL-----------RT 437

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1277 YAKEVAGLRQLLLESQ----------SQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRrqkltaeFEEAQRTACR 1346
Cdd:PRK02224  438 ARERVEEAEALLEAGKcpecgqpvegSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER-------AEDLVEAEDR 510

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568918950 1347 IQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAED 1422
Cdd:PRK02224  511 IERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKE 586
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 171-423 2.61e-09

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 61.94  E-value: 2.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   171 EATPKEV--PMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEG---AQNQAKKGEGAQNQAKKGEGAQ 245
Cdd:TIGR00927  643 ERTGEEGerPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGeieAKEADHKGETEAEEVEHEGETE 722

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   246 NQGKKGEG-AQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGaqnQAKKGEGAQNQGKKGEGA 324
Cdd:TIGR00927  723 AEGTEDEGeIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEG---EIQAGEDGEMKGDEGAEG 799

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   325 QNQSKKGEGAQNQAKKGEGGQNQAKKGEGaqnqaKKGEGAQNQAKKGEGVQNQAKKGVEGaQNQGKKGEANQNQAKKGEG 404
Cdd:TIGR00927  800 KVEHEGETEAGEKDEHEGQSETQADDTEV-----KDETGEQELNAENQGEAKQDEKGVDG-GGGSDGGDSEEEEEEEEEE 873

                          250
                   ....*....|....*....
gi 568918950   405 GQNQTKKGEGPQNQGKKGE 423
Cdd:TIGR00927  874 EEEEEEEEEEEEEEEENEE 892
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1048-1403 2.75e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 2.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1048 LKELESQVSCLEKETSELKEAMEQQKgknndlREKNWKAmEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKEtll 1127
Cdd:COG1196   195 LGELERQLEPLERQAEKAERYRELKE------ELKELEA-ELLLLKLRELEAELEELEAELEELEAELEELEAELAE--- 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1128 allpglsisahqnyaewlqefKEKGSELLKkpptlepsmdivLKLREAEETQNSLQAEcdqYRTILAETEGMLKDLQKSV 1207
Cdd:COG1196   265 ---------------------LEAELEELR------------LELEELELELEEAQAE---EYELLAELARLEQDIARLE 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1208 EEEERVwKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQL 1287
Cdd:COG1196   309 ERRREL-EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1288 LLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAgplESSGKEE 1367
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE---EEALLEL 464

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 568918950 1368 ITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQL 1403
Cdd:COG1196   465 LAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500
PTZ00121 PTZ00121
MAEBL; Provisional
 209-623 3.62e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 3.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  209 KKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEgaqnQGKKGEGAQNQG 288
Cdd:PTZ00121 1378 KKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE----EAKKADEAKKKA 1453

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  289 KKGEGAQNQAKKGEgaqnQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEgaqnQAKKGEGAQ--N 366
Cdd:PTZ00121 1454 EEAKKAEEAKKKAE----EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKAD----EAKKAEEAKkaD 1525

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  367 QAKKGEgvqnQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQD--KKIEGAQNQGKKPEG 444
Cdd:PTZ00121 1526 EAKKAE----EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEeaKKAEEARIEEVMKLY 1601

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  445 TSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEgAQNQGKKGEG 524
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA-EEDKKKAEEA 1680

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  525 PQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDgnPNQGKKGEGASNQNRKTDT 604
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA--EEDKKKAEEAKKDEEEKKK 1758

                         410
                  ....*....|....*....
gi 568918950  605 VANQGTKQEGVSNQVKKSE 623
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEK 1777
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
885-1355 4.59e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.23  E-value: 4.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  885 ELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEE--ALQKRLEEVTRELCRAQTSHAN 962
Cdd:PRK03918  239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSR 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  963 LRADAEKAQEQQQRVAELHSK---LQSSEVEVKSKCEELSSLHGQLKEARAENSQLtERIRSIEALLEAGQAQDTQASHA 1039
Cdd:PRK03918  319 LEEEINGIEERIKELEEKEERleeLKKKLKELEKRLEELEERHELYEEAKAKKEEL-ERLKKRLTGLTPEKLEKELEELE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1040 EANQQQTR-LKELESQVSCLEKETSELKEAMEQQKGKNN---------------DLREKNWKAMEALALAERACEEKLRS 1103
Cdd:PRK03918  398 KAKEEIEEeISKITARIGELKKEIKELKKAIEELKKAKGkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEKERK 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1104 LTQAKEESEKQLHLAEAQTK-ETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLK-LREAEETQNS 1181
Cdd:PRK03918  478 LRKELRELEKVLKKESELIKlKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKeLEKLEELKKK 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1182 LQAECDQYRTILAETEGMLKDLQ----KSVEEEERVWKaKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTS 1257
Cdd:PRK03918  558 LAELEKKLDELEEELAELLKELEelgfESVEELEERLK-ELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELA 636

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1258 HLEAELEKHMAAASAECQNYAKE-VAGLRQLLLESQSQLdeakSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAE 1336
Cdd:PRK03918  637 ETEKRLEELRKELEELEKKYSEEeYEELREEYLELSREL----AGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE 712

                         490
                  ....*....|....*....
gi 568918950 1337 FEEAQRTACRIQEELEKLR 1355
Cdd:PRK03918  713 LEKLEKALERVEELREKVK 731
PTZ00121 PTZ00121
MAEBL; Provisional
 749-1341 5.38e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 5.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  749 KATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASY 828
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE 1402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  829 R----DHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQEnsilrdalnQATSQVESKQNTELAKLRQELSKVNKELVEKS 904
Cdd:PTZ00121 1403 DkkkaDELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE---------EAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  905 EASRQEEQQRKALEA--KAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHS 982
Cdd:PTZ00121 1474 EAKKKAEEAKKADEAkkKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  983 KLQSSEVEVKSKCEELSSLHGQLKEA--RAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEK 1060
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEDKNMAlrKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1061 ETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKEtllallpglsisahQN 1140
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE--------------AE 1699

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1141 YAEWLQEFKEKGSELLKKPPTLEPSMDI-VLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVG 1219
Cdd:PTZ00121 1700 EAKKAEELKKKEAEEKKKAEELKKAEEEnKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1220 AAEEELHKsrvtvkhledivEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAK 1299
Cdd:PTZ00121 1780 VIEEELDE------------EDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEAD 1847

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 568918950 1300 sEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQ 1341
Cdd:PTZ00121 1848 -AFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEAD 1888
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
761-1027 1.78e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 1.78e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  761 KRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAsekakaaageakvkkQLVAREQEIAAVQArmqasYRDHVKEVQQLQG 840
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELD---------------ALQERREALQRLAE-----YSWDEIDVASAER 668

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  841 KIRTLQEQLEN--GPNTQLARLQQENSILRDALNQATSQVESKQ------NTELAKLRQELSKVNKELVEKSEASRQEEQ 912
Cdd:COG4913   669 EIAELEAELERldASSDDLAALEEQLEELEAELEELEEELDELKgeigrlEKELEQAEEELDELQDRLEAAEDLARLELR 748

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  913 QRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSH--------ANLRADAEKAQEqqqrVAELHSKL 984
Cdd:COG4913   749 ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFnrewpaetADLDADLESLPE----YLALLDRL 824

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568918950  985 QSSEV--------EVKSKC--EELSSLHGQLKEARAEnsqLTERIRSIEALLE 1027
Cdd:COG4913   825 EEDGLpeyeerfkELLNENsiEFVADLLSKLRRAIRE---IKERIDPLNDSLK 874
PTZ00121 PTZ00121
MAEBL; Provisional
 227-684 2.53e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.00  E-value: 2.53e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  227 QAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQN--QGKKGEGAQNQGKKGEGAQNQAKKGEGA 304
Cdd:PTZ00121 1201 KAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNneEIRKFEEARMAHFARRQAAIKAEEARKA 1280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  305 QNQAKKGEGAQ-NQGKKGEgaqnQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQA----KKGEGAQNQAKKGEGVQNQAK 379
Cdd:PTZ00121 1281 DELKKAEEKKKaDEAKKAE----EKKKADEAKKKAEEAKKADEAKKKAEEAKKKAdaakKKAEEAKKAAEAAKAEAEAAA 1356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  380 KGVEGAQNQGKKGEANQNQAKK-GEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQ 458
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEKKKEEAKKkADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEA 1436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  459 GKKGEgaqnQGKKGEGAQNQGKKGEGAQNQGKKGEgaqnQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQ 538
Cdd:PTZ00121 1437 KKKAE----EAKKADEAKKKAEEAKKAEEAKKKAE----EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA 1508

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  539 GKKGEGAQ--------NQGKKGEGAQ--NQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQ 608
Cdd:PTZ00121 1509 KKKADEAKkaeeakkaDEAKKAEEAKkaDEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKK 1588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  609 GTK---QEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVD----AAANQGKKSEMAPAQGQKASMVQSQEAP 681
Cdd:PTZ00121 1589 AEEariEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEqlkkKEAEEKKKAEELKKAEEENKIKAAEEAK 1668


                  ...
gi 568918950  682 KQD 684
Cdd:PTZ00121 1669 KAE 1671
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 809-1104 2.75e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 2.75e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   809 QLVAREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLENGPNtQLARLQQENSILRDALNQATSQVESKQNtELAK 888
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEK-EIEQLEQEEEKLKERLEELEEDLSSLEQ-EIEN 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   889 LRQELSKVNKELVEKSEASRQEEQQRKALEAKAAtfEKQVLQLQAsHKESEEALQKRLEEVTRELCRAQTSHANLRADAE 968
Cdd:TIGR02169  756 VKSELKELEARIEELEEDLHKLEEALNDLEARLS--HSRIPEIQA-ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE 832

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   969 KA-QEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQdtqashaeANQQQTR 1047
Cdd:TIGR02169  833 KEiQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ--------LRELERK 904

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568918950  1048 LKELESQVSCLEKETSELKEAMEQQKGKNNDLrEKNWKAM----------EALALAERACEEKLRSL 1104
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALEEELSEI-EDPKGEDeeipeeelslEDVQAELQRVEEEIRAL 970
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 421-644 3.38e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 58.47  E-value: 3.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   421 KGEAAQKQDKKiEGAQNQGKKPEGTsnQGKKGEGAQNQGKKGEGAQNQGK-KGEGAQNQGKKGEGAQNQGKKGEGAQNqg 499
Cdd:TIGR00927  632 KGDVAEAEHTG-ERTGEEGERPTEA--EGENGEESGGEAEQEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH-- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   500 kKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGK-KGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQ 578
Cdd:TIGR00927  707 -KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEgEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQA 785

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568918950   579 GKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEgvsNQVKKSEGSPNQGKKAEGAPNQGKKKDG 644
Cdd:TIGR00927  786 GEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSE---TQADDTEVKDETGEQELNAENQGEAKQD 848
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
809-1024 4.06e-08

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 58.10  E-value: 4.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  809 QLVAREQEIAAVQARMQAsYR------DHVKEVQQLQGKIRTLQEQLENgPNTQLARLQQENSILRDALNQATSQV-ESK 881
Cdd:COG3206   183 QLPELRKELEEAEAALEE-FRqknglvDLSEEAKLLLQQLSELESQLAE-ARAELAEAEARLAALRAQLGSGPDALpELL 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  882 QNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVlqlqashkesEEALQKRLEEVTRELCRAQTSHA 961
Cdd:COG3206   261 QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQL----------QQEAQRILASLEAELEALQAREA 330

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568918950  962 NLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEA 1024
Cdd:COG3206   331 SLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVRVIDP 393
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 757-1432 5.52e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 57.67  E-value: 5.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   757 VAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQ 836
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   837 QLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKA 916
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEK 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   917 LEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRAD-----AEKAQEQQQRVAELHSKLQSSEVEV 991
Cdd:pfam02463  324 KKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEellakKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   992 KSKCEELSSLHGQLKE-ARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESqvscLEKETSELKEAME 1070
Cdd:pfam02463  404 EKEAQLLLELARQLEDlLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE----LKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1071 QQKGKNNDLREKNWKAMEALAlAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSIsAHQNYAEWLQEFKE 1150
Cdd:pfam02463  480 VKLQEQLELLLSRQKLEERSQ-KESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV-AISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1151 KGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELHKSRV 1230
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1231 TVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAglrqLLLESQSQLDEAKSEAQKQSDELA 1310
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESEL----AKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1311 LLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACrIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLgrAAI 1390
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEE-EEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK--VEE 790

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 568918950  1391 KLQELLKTTQEQLTKEKDTVKKLQEQLGKAEDGSSSKEGTSV 1432
Cdd:pfam02463  791 EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKE 832
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1169-1417 5.66e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 5.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1169 VLKLRE-AEETQNSL---QAECDQYRTILAETEGMLKDLQKSVEEEER--------------VWKAKVGAAEEELHKSRV 1230
Cdd:TIGR02168  167 ISKYKErRKETERKLertRENLDRLEDILNELERQLKSLERQAEKAERykelkaelrelelaLLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1231 TVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGL--------------RQLLLESQSQLD 1296
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeqqkqilrerlanlERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1297 EAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLE-----------SSGK 1365
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLelqiaslnneiERLE 406

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568918950  1366 EEITQLKERLEKEKRLTSDLGRAAIKLQelLKTTQEQLTKEKDTVKKLQEQL 1417
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEELEELQEEL 456
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 833-1069 6.54e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.70  E-value: 6.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  833 KEVQQLQGKIRTLQEQLENgPNTQLARLQQENSILRDALNQATSQVeSKQNTELAKLRQELSKVNKELvekSEASRQEEQ 912
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAE-LEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAEL---AELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  913 QRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVK 992
Cdd:COG4942    95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568918950  993 skceELSSLHGQLKEARAENSQLTERIRSIEALLEagqaQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAM 1069
Cdd:COG4942   175 ----ELEALLAELEEERAALEALKAERQKLLARLE----KELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 833-1419 8.41e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 57.29  E-value: 8.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   833 KEVQQLQGKIRTLQEQLENGPNTQlARLQQENSILRDALNQAtsqveskqntELAKLRQELSKVNKELVEKSEASRQEEQ 912
Cdd:TIGR00618  260 QLLKQLRARIEELRAQEAVLEETQ-ERINRARKAAPLAAHIK----------AVTQIEQQAQRIHTELQSKMRSRAKLLM 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   913 QRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTR--ELCRAQTSHANLRA---DAEKAQEQQQRVAELHSKLQSS 987
Cdd:TIGR00618  329 KRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIreISCQQHTLTQHIHTlqqQKTTLTQKLQSLCKELDILQRE 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   988 EVEVKSKCEELSSLHGQLKEARAEnSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKE 1067
Cdd:TIGR00618  409 QATIDTRTSAFRDLQGQLAHAKKQ-QELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1068 AMEQQKGKNNDLREKNWKAMEAL-----ALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLsisahQNYA 1142
Cdd:TIGR00618  488 KKAVVLARLLELQEEPCPLCGSCihpnpARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQR-----ASLK 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1143 EWLQEFKEKGSELLKKPPTLEPSMDIVLKlrEAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAE 1222
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQN--ITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQE 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1223 EELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEA 1302
Cdd:TIGR00618  641 LALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1303 QKQSDELALLKTQLERTEATL-----EAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEITQLKERLEK 1377
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALnqslkELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHL 800

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 568918950  1378 EKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGK 1419
Cdd:TIGR00618  801 LKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSA 842
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
893-1421 1.25e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 56.61  E-value: 1.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  893 LSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKEseeaLQKRLEEVTRELcraqtshANLRADAEKAQE 972
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINE----ISSELPELREEL-------EKLEKEVKELEE 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  973 QQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEAL---------LEAGQAQDTQASH----- 1038
Cdd:PRK03918  236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELkekaeeyikLSEFYEEYLDELReiekr 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1039 -----AEANQQQTRLKELESqvscLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEK 1113
Cdd:PRK03918  316 lsrleEEINGIEERIKELEE----KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEK 391

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1114 QLHLAEAQTKETLLALlpgLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTIL 1193
Cdd:PRK03918  392 ELEELEKAKEEIEEEI---SKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKEL 468

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1194 AETEGMLKDLQKSVEEEErvwkaKVGAAEEELHKSRVTVKHLEDIVEKLKG----ELESS----DQVREHTSHLEAE--- 1262
Cdd:PRK03918  469 KEIEEKERKLRKELRELE-----KVLKKESELIKLKELAEQLKELEEKLKKynleELEKKaeeyEKLKEKLIKLKGEiks 543

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1263 ----------LEKHMAAASAECQNYAKEVAGL----RQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQT 1328
Cdd:PRK03918  544 lkkelekleeLKKKLAELEKKLDELEEELAELlkelEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKK 623

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1329 RRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGK-EEITQLKERLEKE-KRLTSDLGRAAIKLQELLKTTqEQLTKE 1406
Cdd:PRK03918  624 LEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyEELREEYLELSRElAGLRAELEELEKRREEIKKTL-EKLKEE 702

                         570
                  ....*....|....*
gi 568918950 1407 KDTVKKLQEQLGKAE 1421
Cdd:PRK03918  703 LEEREKAKKELEKLE 717
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1192-1421 1.26e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 1.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1192 ILAETEGMLKDLQKSVEEEERvwkAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESsdqvrehtshlEAELEKHMAAAS 1271
Cdd:COG1196   194 ILGELERQLEPLERQAEKAER---YRELKEELKELEAELLLLKLRELEAELEELEAE-----------LEELEAELEELE 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1272 AECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEEL 1351
Cdd:COG1196   260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1352 EKLRAAgpLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAE 1421
Cdd:COG1196   340 EELEEE--LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 401-643 1.81e-07

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 56.16  E-value: 1.81e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   401 KGEGGQNQTKkGEGPQNQGKKGEAAQKQDKKIEGAQNQgkKPEGTSNQGK-KGEGAQNQGKKGEGAQNQGKKGEGAQNqg 479
Cdd:TIGR00927  632 KGDVAEAEHT-GERTGEEGERPTEAEGENGEESGGEAE--QEGETETKGEnESEGEIPAERKGEQEGEGEIEAKEADH-- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   480 kKGEGAQNQGKKGEGAQNQGKKGEGaqnQGKKGEGAQNQGKKGEGpQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQG 559
Cdd:TIGR00927  707 -KGETEAEEVEHEGETEAEGTEDEG---EIETGEEGEEVEDEGEG-EAEGKHEVETEGDRKETEHEGETEAEGKEDEDEG 781

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   560 KKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQG 639
Cdd:TIGR00927  782 EIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGG 861


                   ....
gi 568918950   640 KKKD 643
Cdd:TIGR00927  862 DSEE 865
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 383-592 2.60e-07

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 55.30  E-value: 2.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  383 EGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQ-NQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKK 461
Cdd:PRK12678   56 KEARGGGAAAAAATPAAPAAAARRAARAAAAARQaEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  462 GEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKK 541
Cdd:PRK12678  136 AARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRR 215

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568918950  542 GEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGkkgDGNPNQGKKG 592
Cdd:PRK12678  216 EERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGD---DGEGRGGRRG 263
PRK11281 PRK11281
mechanosensitive channel MscK;
818-1104 3.03e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 55.30  E-value: 3.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  818 AAVQARMQAsyrdhVKEVQQLQGKIRTLQEQLENGPNT--QLARLQQENSILRDALNQATSQVESKQnTELAKL------ 889
Cdd:PRK11281   39 ADVQAQLDA-----LNKQKLLEAEDKLVQQDLEQTLALldKIDRQKEETEQLKQQLAQAPAKLRQAQ-AELEALkddnde 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  890 --RQELSKVNKELVEKSEASRQEEQQRkaLEAKAATFEKQVLQLQASHKESEEAL---QKRLEEVTRELCRAQTSHANLR 964
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQN--AQNDLAEYNSQLVSLQTQPERAQAALyanSQRLQQIRNLLKGGKVGGKALR 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  965 ADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELssLHGQLKEARAENSQLTERIRSIEAL-----LEAGQAQDTQASHA 1039
Cdd:PRK11281  191 PSQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDL--LQKQRDYLTARIQRLEHQLQLLQEAinskrLTLSEKTVQEAQSQ 268

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568918950 1040 EANQQQTR----LKELES--QVS-CLEKETSELKEAMEQqkgknnDLREKNWkaMEALALAERACEEKLRSL 1104
Cdd:PRK11281  269 DEAARIQAnplvAQELEInlQLSqRLLKATEKLNTLTQQ------NLRVKNW--LDRLTQSERNIKEQISVL 332
mukB PRK04863
chromosome partition protein MukB;
863-1377 3.91e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.96  E-value: 3.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  863 ENSILRDALNQATSQV-ESKQNTELAKLRQELSKVNKELVEKSEA------SRQEEQQRKALEaKAATFEKQVlqlqASH 935
Cdd:PRK04863  224 ENSGVRKAFQDMEAALrENRMTLEAIRVTQSDRDLFKHLITESTNyvaadyMRHANERRVHLE-EALELRREL----YTS 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  936 KESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRV--AELHSKlqssevevkskceelsslhgQLKEARAENS 1013
Cdd:PRK04863  299 RRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVqtALRQQE--------------------KIERYQADLE 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1014 QLTERirsieaLLEAGQAQDTQASHAEANQQQTRLKELEsqVSCLEKETSELKEAMEQQKGKNNDLREknwkAMEALALA 1093
Cdd:PRK04863  359 ELEER------LEEQNEVVEEADEQQEENEARAEAAEEE--VDELKSQLADYQQALDVQQTRAIQYQQ----AVQALERA 426

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1094 ERACEekLRSLTQAK-EESEKQLHLAEAQTKETLLALLPGLSIS--AHQNYAEWLQEFKEKGSELlkkpptlepsmdivl 1170
Cdd:PRK04863  427 KQLCG--LPDLTADNaEDWLEEFQAKEQEATEELLSLEQKLSVAqaAHSQFEQAYQLVRKIAGEV--------------- 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1171 klrEAEETQNSLQAECDQYRTilaetegmlkdlQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSD 1250
Cdd:PRK04863  490 ---SRSEAWDVARELLRRLRE------------QRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDED 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1251 QVREHTSHLEAELEKhmaaasaecqnyakevaglrqlLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRR 1330
Cdd:PRK04863  555 ELEQLQEELEARLES----------------------LSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDAL 612

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568918950 1331 QKLTAEFEEAQRTACR----IQEELEKLRAAGPLESSGKEEITQLKERLEK 1377
Cdd:PRK04863  613 ARLREQSGEEFEDSQDvteyMQQLLERERELTVERDELAARKQALDEEIER 663
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
763-916 4.22e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 4.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  763 QLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQ-LVAREQEIAAVQARMQASYRDHVKEVQQLQGK 841
Cdd:COG3206   220 QLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQqLRAQLAELEAELAELSARYTPNHPDVIALRAQ 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  842 IRTLQEQLENGPNTQLARLQQENSILR---DALNQATSQVESKQNT------ELAKLRQELsKVNKE----LVEKSEASR 908
Cdd:COG3206   300 IAALRAQLQQEAQRILASLEAELEALQareASLQAQLAQLEARLAElpeleaELRRLEREV-EVARElyesLLQRLEEAR 378


                  ....*...
gi 568918950  909 QEEQQRKA 916
Cdd:COG3206   379 LAEALTVG 386
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 757-1332 4.49e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.59  E-value: 4.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   757 VAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQ 836
Cdd:TIGR00618  296 AAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQH 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   837 QLQGKIRTLQEQLE-----------------NGPNTQLARLQQENSILRDALNQATSQVESKQNTEL-----AKLRQELS 894
Cdd:TIGR00618  376 TLTQHIHTLQQQKTtltqklqslckeldilqREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELcaaaiTCTAQCEK 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   895 KVNKELVEKSEASRQEEQQRKALEAKAATfEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQ 974
Cdd:TIGR00618  456 LEKIHLQESAQSLKEREQQLQTKEQIHLQ-ETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGE 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   975 QRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASH---AEANQQQTRLKEL 1051
Cdd:TIGR00618  535 QTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDlteKLSEAEDMLACEQ 614

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1052 ESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLP 1131
Cdd:TIGR00618  615 HALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTY 694

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1132 GLSISAHQNYAEWLQEFKEKGSEllkkpptlepsmdivlklREAEETQNSLQAEcdqyRTILAETEGMLKDLQKSVEEEE 1211
Cdd:TIGR00618  695 WKEMLAQCQTLLRELETHIEEYD------------------REFNEIENASSSL----GSDLAAREDALNQSLKELMHQA 752

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1212 RvWKAKVGAAEEELHKSRVTVK-HLEDIVEKLKGELESSDQVREHTSHLEAELEkhmaaasAECQNYAKEVAGLRQLLLE 1290
Cdd:TIGR00618  753 R-TVLKARTEAHFNNNEEVTAAlQTGAELSHLAAEIQFFNRLREEDTHLLKTLE-------AEIGQEIPSDEDILNLQCE 824

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 568918950  1291 SQSQ-LDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQK 1332
Cdd:TIGR00618  825 TLVQeEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQE 867
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 906-1395 5.18e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 54.57  E-value: 5.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  906 ASRQEEQQRKALEAKAATFEKQVLQLQAshkeseealQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVaelhsklq 985
Cdd:COG3096   277 ANERRELSERALELRRELFGARRQLAEE---------QYRLVEMARELEELSARESDLEQDYQAASDHLNLV-------- 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  986 ssevevkskceeLSSLHGQLKEAR--AENSQLTERIRSIEALLEAGQAQdtqasHAEAnqqQTRLKELESQVSCLEKETS 1063
Cdd:COG3096   340 ------------QTALRQQEKIERyqEDLEELTERLEEQEEVVEEAAEQ-----LAEA---EARLEAAEEEVDSLKSQLA 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1064 ELKEAMEQQKGKNNDLREknwkAMEALALAERACEEKLRSLTQAKEESEkQLHLAEAQTKETLLALLPGLSIS--AHQNY 1141
Cdd:COG3096   400 DYQQALDVQQTRAIQYQQ----AVQALEKARALCGLPDLTPENAEDYLA-AFRAKEQQATEEVLELEQKLSVAdaARRQF 474

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1142 aewlqefkEKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAEtegmLKDLQKSVEEEERVwkakvgaa 1221
Cdd:COG3096   475 --------EKAYELVCKIAGEVERSQAWQTARELLRRYRSQQALAQRLQQLRAQ----LAELEQRLRQQQNA-------- 534

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1222 eEELhksrvtvkhLEDIVEKLKGELESSDQVREHTSHLEAELEKhmaaasaecqnyakevaglrqlLLESQSQLDEAKSE 1301
Cdd:COG3096   535 -ERL---------LEEFCQRIGQQLDAAEELEELLAELEAQLEE----------------------LEEQAAEAVEQRSE 582

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1302 AQKQSDELALLKTQLERTEATLEAEQTRRQKLT----AEFEEAQRTACRIQEELEKLRAAgpleSSGKEEITQLKERLEK 1377
Cdd:COG3096   583 LRQQLEQLRARIKELAARAPAWLAAQDALERLReqsgEALADSQEVTAAMQQLLEREREA----TVERDELAARKQALES 658

                         490
                  ....*....|....*....
gi 568918950 1378 E-KRLTSDLGRAAIKLQEL 1395
Cdd:COG3096   659 QiERLSQPGGAEDPRLLAL 677
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
760-1124 7.06e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 7.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  760 LKRQLEEKEKLLATEQEDAAVAKSKLRELnkEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQAsYRDHVKEVQQLQ 839
Cdd:COG4717    93 LQEELEELEEELEELEAELEELREELEKL--EKLLQLLPLYQELEALEAELAELPERLEELEERLEE-LRELEEELEELE 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  840 GKIRTLQEQLENGPNT-------QLARLQQENSILRDALNQATSQVESKQNtELAKLRQELSKVNKELVEKSEASR-QEE 911
Cdd:COG4717   170 AELAELQEELEELLEQlslateeELQDLAEELEELQQRLAELEEELEEAQE-ELEELEEELEQLENELEAAALEERlKEA 248

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  912 QQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQE-------QQQRVAELHSKL 984
Cdd:COG4717   249 RLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAlpaleelEEEELEELLAAL 328

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  985 QSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIR------SIEALLEAGQAQDTQA------SHAEANQQQTRLKELE 1052
Cdd:COG4717   329 GLPPDLSPEELLELLDRIEELQELLREAEELEEELQleeleqEIAALLAEAGVEDEEElraaleQAEEYQELKEELEELE 408

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568918950 1053 SQvscLEKETSELKEAMEQQKGKNNDLR-EKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKE 1124
Cdd:COG4717   409 EQ---LEELLGELEELLEALDEEELEEElEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL 478
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 885-1124 9.19e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.80  E-value: 9.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  885 ELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKqvLQLQASHKEsEEALQKRLEEVTRELCRAQTSHA--- 961
Cdd:COG3096   837 ELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNK--LLPQANLLA-DETLADRLEELREELDAAQEAQAfiq 913

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  962 --------------NLRADAEKAQEQQQRVAELHSKLQssevEVKSKCEELSSL-----H-------GQLKEARAENSQL 1015
Cdd:COG3096   914 qhgkalaqleplvaVLQSDPEQFEQLQADYLQAKEQQR----RLKQQIFALSEVvqrrpHfsyedavGLLGENSDLNEKL 989

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1016 TERIRSIE-ALLEAG-QAQDTQASHAEANQQQTRLKelesqvSCLEKETSELKEAMEQQKgknnDLREKNWKAMEALALA 1093
Cdd:COG3096   990 RARLEQAEeARREAReQLRQAQAQYSQYNQVLASLK------SSRDAKQQTLQELEQELE----ELGVQADAEAEERARI 1059

                         250       260       270
                  ....*....|....*....|....*....|..
gi 568918950 1094 ERA-CEEKLRSLTQAKEESEKQLHLAEAQTKE 1124
Cdd:COG3096  1060 RRDeLHEELSQNRSRRSQLEKQLTRCEAEMDS 1091
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
812-1318 1.33e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 1.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  812 AREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLENGpNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQ 891
Cdd:COG4913   267 ARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARL-EAELERLEARLDALREELDELEAQIRGNGGDRLEQLER 345

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  892 ELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQ 971
Cdd:COG4913   346 EIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE 425

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  972 ---------------EQQQRVAELHSKLQSSEVEVKSKCEEL--------------SSLHGQ----------LKEARA-- 1010
Cdd:COG4913   426 aeiaslerrksnipaRLLALRDALAEALGLDEAELPFVGELIevrpeeerwrgaieRVLGGFaltllvppehYAAALRwv 505

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1011 ENSQLTERIRsIEALLEAGQAQDTQASHA---------EANQQQTRLKELESQVSCLEKETSElkEAMEQ---------- 1071
Cdd:COG4913   506 NRLHLRGRLV-YERVRTGLPDPERPRLDPdslagkldfKPHPFRAWLEAELGRRFDYVCVDSP--EELRRhpraitragq 582

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1072 --------QKGKNNDLREKN---WKAMEALALAER---ACEEKLRSLTQAKEESEKQLHLAEAQtKETLLALLPglSISA 1137
Cdd:COG4913   583 vkgngtrhEKDDRRRIRSRYvlgFDNRAKLAALEAelaELEEELAEAEERLEALEAELDALQER-REALQRLAE--YSWD 659

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1138 HQNYAEWLQEFKEKGSELLKkpptLEPSMDIVLKLR----EAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERV 1213
Cdd:COG4913   660 EIDVASAEREIAELEAELER----LDASSDDLAALEeqleELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR 735

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1214 WKAKVGAAEEELHKS---RVTVKHLEDIVEKLKGELESS-DQVREHTSHLEAELEKHMAAAS----AECQNYAKEVAG-- 1283
Cdd:COG4913   736 LEAAEDLARLELRALleeRFAAALGDAVERELRENLEERiDALRARLNRAEEELERAMRAFNrewpAETADLDADLESlp 815

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....
gi 568918950 1284 -----LRQL----LLESQSQLDEAKSEAQKQsdELALLKTQLER 1318
Cdd:COG4913   816 eylalLDRLeedgLPEYEERFKELLNENSIE--FVADLLSKLRR 857
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
747-1099 1.77e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.46  E-value: 1.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  747 WHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQA 826
Cdd:COG4717   134 LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEE 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  827 SYRDHVKEVQQLQGKIRTLQEQLENGPNTQlaRLQQENSILRDA-------LNQATSQVESKQNTELAKLRQELSKVNKE 899
Cdd:COG4717   214 ELEEAQEELEELEEELEQLENELEAAALEE--RLKEARLLLLIAaallallGLGGSLLSLILTIAGVLFLVLGLLALLFL 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  900 LVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKR----LEEVTRELCRAQTSHANLRADAEKAQEQQQ 975
Cdd:COG4717   292 LLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEelleLLDRIEELQELLREAEELEEELQLEELEQE 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  976 RVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQ----------- 1044
Cdd:COG4717   372 IAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEEleeleeeleel 451

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568918950 1045 QTRLKELESQVSCLEKET--SELKEAMEQQKGKNNDLREKNWKAMEALALAERACEE 1099
Cdd:COG4717   452 REELAELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEAREE 508
Gag_spuma pfam03276
Spumavirus gag protein;
347-478 2.37e-06

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 52.06  E-value: 2.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   347 QAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVE---GAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQ----NQG 419
Cdd:pfam03276  480 QIRASRGPGPGPSAGEGRGGPANEGRGGPCNAGGGNDcgaNGQNDGGENIQNGGQELRSQGGQNLRSGGGQGQrwgeGRG 559

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568918950   420 KKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGegaqNQGKKGEGAQNQGKKGEGAQNQ 478
Cdd:pfam03276  560 NRENENTENSEQRPREIQAGSGRPGNAGQGVKG----AAGQGGKGAAGRGGRGNGAGDQ 614
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 882-1114 2.49e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 2.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  882 QNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKEseeaLQKRLEEVTRELCRAQTSHA 961
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA----LEQELAALEAELAELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  962 NLRADAEKAQEQ-QQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQAShAE 1040
Cdd:COG4942    94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE-AE 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568918950 1041 ANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLReknwKAMEALALAERACEEKLRSLTQAKEESEKQ 1114
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELA----AELAELQQEAEELEALIARLEAEAAAAAER 242
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 838-1423 2.84e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.10  E-value: 2.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   838 LQGKIRTLQEQLeNGPNTQLARLQQENSILRDALNQATSQV--ESKQNTELAKLRQELSKVNKELVE---KSEASRQE-E 911
Cdd:pfam01576  129 TEAKIKKLEEDI-LLLEDQNSKLSKERKLLEERISEFTSNLaeEEEKAKSLSKLKNKHEAMISDLEErlkKEEKGRQElE 207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   912 QQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQS----- 986
Cdd:pfam01576  208 KAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESeraar 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   987 --SEVEVKSKCEELSSLHGQLKEA-RAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESqvsclekeTS 1063
Cdd:pfam01576  288 nkAEKQRRDLGEELEALKTELEDTlDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQA--------LE 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1064 ELKEAMEQQKgKNNDLREKNWKAMEAlALAERACEekLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQ---- 1139
Cdd:pfam01576  360 ELTEQLEQAK-RNKANLEKAKQALES-ENAELQAE--LRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELaekl 435

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1140 --------NYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREaEETQNSLQAEcDQYRTILAETEGMLKDLQKSVEEEE 1211
Cdd:pfam01576  436 sklqseleSVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQ-EETRQKLNLS-TRLRQLEDERNSLQEQLEEEEEAKR 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1212 RVWK------AKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLR 1285
Cdd:pfam01576  514 NVERqlstlqAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQR 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1286 QL---LLESQSQLDEAKSEAQKQSDELAllkTQLERTEATLEAEQTRRQKLTAEFEEAQRTacriQEELEKLRaagples 1362
Cdd:pfam01576  594 QLvsnLEKKQKKFDQMLAEEKAISARYA---EERDRAEAEAREKETRALSLARALEEALEA----KEELERTN------- 659

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568918950  1363 sgkeeiTQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAEDG 1423
Cdd:pfam01576  660 ------KQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDA 714
PRK11281 PRK11281
mechanosensitive channel MscK;
887-1122 4.61e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.45  E-value: 4.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  887 AKLRQELSKVNKelvekseaSRQEEQQRKALEAkaaTFEKQVLQLQ--ASHKESEEALQKRLEEVTRELCRAQTSHANLR 964
Cdd:PRK11281   39 ADVQAQLDALNK--------QKLLEAEDKLVQQ---DLEQTLALLDkiDRQKEETEQLKQQLAQAPAKLRQAQAELEALK 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  965 ADAEKAQEQ----------QQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDT 1034
Cdd:PRK11281  108 DDNDEETREtlstlslrqlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGK 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1035 QASHAEANQQQTRLKELESQVSCLEKET---SELKEAMEQQKgknNDLREKNWKAMEALALAERACEEKLRSLTQAK-EE 1110
Cdd:PRK11281  188 ALRPSQRVLLQAEQALLNAQNDLQRKSLegnTQLQDLLQKQR---DYLTARIQRLEHQLQLLQEAINSKRLTLSEKTvQE 264

                         250
                  ....*....|..
gi 568918950 1111 SEKQLHLAEAQT 1122
Cdd:PRK11281  265 AQSQDEAARIQA 276
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 451-663 4.73e-06

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 51.53  E-value: 4.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   451 KGEGAQNQgKKGEGAQNQGKKGEGAQnqGKKGEgaqnqgKKGEGAQNQGKKGEGAQNQGK-----------KGEG---AQ 516
Cdd:TIGR00927  632 KGDVAEAE-HTGERTGEEGERPTEAE--GENGE------ESGGEAEQEGETETKGENESEgeipaerkgeqEGEGeieAK 702

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   517 NQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGK-KAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGA 595
Cdd:TIGR00927  703 EADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEgEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGE 782

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568918950   596 SNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKkvdAAANQGKKSE 663
Cdd:TIGR00927  783 IQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQEL---NAENQGEAKQ 847
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 760-1264 6.00e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.99  E-value: 6.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   760 LKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQE----IAAVQARMQASYRDHVKEV 835
Cdd:pfam12128  331 HGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnnrdIAGIKDKLAKIREARDRQL 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   836 QQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRK 915
Cdd:pfam12128  411 AVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERL 490

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   916 ALEAKAA--TFEKQVLQLQASHKESEEaLQKRLEEVTRELC-RAQTSHANLRADAEKAQEQQQRV---AELHSKLQSSEV 989
Cdd:pfam12128  491 QSELRQArkRRDQASEALRQASRRLEE-RQSALDELELQLFpQAGTLLHFLRKEAPDWEQSIGKVispELLHRTDLDPEV 569

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   990 EVKSKCEELSsLHG--------QLKEARAENSQLTERIRSIEALLeagqaQDTQASHAEANQQQTRL-KELESQVSCLEK 1060
Cdd:pfam12128  570 WDGSVGGELN-LYGvkldlkriDVPEWAASEEELRERLDKAEEAL-----QSAREKQAAAEEQLVQAnGELEKASREETF 643

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1061 ETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETL-------------- 1126
Cdd:pfam12128  644 ARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKreartekqaywqvv 723

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1127 -------LALLPGLSISAHQNYAEWLQEFKEKGSELLKKpptLEPSMDIVLKLREAEET--------------------- 1178
Cdd:pfam12128  724 egaldaqLALLKAAIAARRSGAKAELKALETWYKRDLAS---LGVDPDVIAKLKREIRTlerkieriavrrqevlryfdw 800

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1179 -QNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTS 1257
Cdd:pfam12128  801 yQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDAN 880


                   ....*..
gi 568918950  1258 HLEAELE 1264
Cdd:pfam12128  881 SEQAQGS 887
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
911-1081 6.33e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 6.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  911 EQQRKALEAKAATFEKQVLQLQASHK-----ESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQ 985
Cdd:COG3206   181 EEQLPELRKELEEAEAALEEFRQKNGlvdlsEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELL 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  986 SSEVevkskceeLSSLHGQLKEARAENSQLTER-------IRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCL 1058
Cdd:COG3206   261 QSPV--------IQQLRAQLAELEAELAELSARytpnhpdVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASL 332

                         170       180
                  ....*....|....*....|...
gi 568918950 1059 EKETSELKEAMEQQKGKNNDLRE 1081
Cdd:COG3206   333 QAQLAQLEARLAELPELEAELRR 355
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 936-1329 9.97e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 9.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   936 KESEEALQKRLEEVTRELCRAQTSHAN-LRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQ 1014
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREKaERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1015 LTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAE 1094
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1095 RACEEKLRSLTQAKEESEKQlhlaeAQTKETLLALLPGLSISAhqnyAEWLQEFKekgsellkkpptlepsmDIVLKLRE 1174
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAEL-----KEELEDLRAELEEVDKEF----AETRDELK-----------------DYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1175 AEETQNSLQAECDQyrtilaetegmLKDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESsdqvre 1254
Cdd:TIGR02169  397 LKREINELKRELDR-----------LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ------ 459

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568918950  1255 htshleaelekhmaaasaecqnyakevagLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTR 1329
Cdd:TIGR02169  460 -----------------------------LAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 200-388 1.11e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 50.38  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   200 KGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGE----GAQNQAKKGEGAQNQGKKGEGAQNQAKKGEG----GQNQAKKG 271
Cdd:TIGR00927  707 KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEevedEGEGEAEGKHEVETEGDRKETEHEGETEAEGkedeDEGEIQAG 786

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   272 EGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQ--SKKGEGAQNQAKKGEGGQNQAK 349
Cdd:TIGR00927  787 EDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQgeAKQDEKGVDGGGGSDGGDSEEE 866

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 568918950   350 KGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQ 388
Cdd:TIGR00927  867 EEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 760-994 1.23e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  760 LKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASekakaaageakVKKQLVAREQEIAAVQARMQASyrdhVKEVQQLQ 839
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAA-----------LARRIRALEQELAALEAELAEL----EKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  840 GKIRTLQEQLENgpntQLARLQQENSILRDALnqatsQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEA 919
Cdd:COG4942    97 AELEAQKEELAE----LLRALYRLGRQPPLAL-----LLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568918950  920 KAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSK 994
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 757-1128 1.26e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 49.82  E-value: 1.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   757 VAILKRQLEEKEKLLATEQEdaavaksKLRELNkemaSEKAKAAAGEAKVKKQLVAREQEIAAVQAR---MQASYRDHVK 833
Cdd:pfam10174  347 VDALRLRLEEKESFLNKKTK-------QLQDLT----EEKSTLAGEIRDLKDMLDVKERKINVLQKKienLQEQLRDKDK 415

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   834 EVQQLQGKIRTLQEQLENgPNTQLARLQQ---ENSILRDALNQATSQVESKQNTELAKLRQElskvNKELVEKSEASRQE 910
Cdd:pfam10174  416 QLAGLKERVKSLQTDSSN-TDTALTTLEEalsEKERIIERLKEQREREDRERLEELESLKKE----NKDLKEKVSALQPE 490

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   911 EQQRKA----LEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHanlradaeKAQEQQQRVAELHSKLQS 986
Cdd:pfam10174  491 LTEKESslidLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAH--------NAEEAVRTNPEINDRIRL 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   987 SEVEVKSKCEE-------LSSLHGQLKEARAENSQLTERIRSIEAL-LEAGQAQDTQASHAEANQQQTRLKELESQVSCL 1058
Cdd:pfam10174  563 LEQEVARYKEEsgkaqaeVERLLGILREVENEKNDKDKKIAELESLtLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEAR 642

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568918950  1059 EKETSELKEAMEQQKGKNNDLREKNWKAMEA----LALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLA 1128
Cdd:pfam10174  643 RREDNLADNSQQLQLEELMGALEKTRQELDAtkarLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLA 716
PTZ00121 PTZ00121
MAEBL; Provisional
 238-1028 1.43e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  238 AKKGEGAQNQGKKGEGAQNQAKKGEGGQ-NQAKKGEGAQNQGKKGEGAQnQGKKGEGAQ--NQAKKGEGAQNQAKKGEGA 314
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKaEEARKAEEAKKKAEDARKAE-EARKAEDARkaEEARKAEDAKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  315 QNQGKKGEGAQNQSKKGEGAQN--QAKKGEggqnQAKKGEGAQnQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQ--NQGK 390
Cdd:PTZ00121 1162 DARKAEEARKAEDAKKAEAARKaeEVRKAE----ELRKAEDAR-KAEAARKAEEERKAEEARKAEDAKKAEAVKkaEEAK 1236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  391 KGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGE---GAQNQGKKGEGAQN 467
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEekkKADEAKKKAEEAKK 1316

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  468 QGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQnqGKKGEGAQNQGKKGEGPQNQAKK-GEGAQNQGKKGEGAQ 546
Cdd:PTZ00121 1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAA--ADEAEAAEEKAEAAEKKKEEAKKkADAAKKKAEEKKKAD 1394

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  547 NQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEgasnQNRKTDTVANQGTKQEGVSNQVKKSEgsp 626
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE----EAKKADEAKKKAEEAKKAEEAKKKAE--- 1467

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  627 nQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEpgppdcdg 706
Cdd:PTZ00121 1468 -EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE-------- 1538

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  707 plflpyktlvstvgsmvFSEGEAQRLIEILSEKTGViqdtwHKATQKgdpvailkRQLEEKEKllatEQEDAAVAKSKLR 786
Cdd:PTZ00121 1539 -----------------AKKAEEKKKADELKKAEEL-----KKAEEK--------KKAEEAKK----AEEDKNMALRKAE 1584

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  787 ELNKemASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQAsyrDHVKEVQQLQGKIRTLQEQLEngpntqlarlqqensi 866
Cdd:PTZ00121 1585 EAKK--AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA---EELKKAEEEKKKVEQLKKKEA---------------- 1643

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  867 lrdalnqatsqvESKQNTELAKLRQELSKVNKElvekSEASRQEEQQRKALEAKAATFEKqvlqlqashKESEEALQKRL 946
Cdd:PTZ00121 1644 ------------EEKKKAEELKKAEEENKIKAA----EEAKKAEEDKKKAEEAKKAEEDE---------KKAAEALKKEA 1698

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  947 EEVTR--ELCRAQTSHANLRADAEKAQEQQQRVAElhsKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEA 1024
Cdd:PTZ00121 1699 EEAKKaeELKKKEAEEKKKAEELKKAEEENKIKAE---EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRK 1775


                  ....
gi 568918950 1025 LLEA 1028
Cdd:PTZ00121 1776 EKEA 1779
COG5022 COG5022
Myosin heavy chain [General function prediction only];
823-1129 1.70e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 49.69  E-value: 1.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  823 RMQASYRDHV--KEVQQLQGKIRTLQEQLENGpNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKEL 900
Cdd:COG5022   798 KLQPLLSLLGsrKEYRSYLACIIKLQKTIKRE-KKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQR 876

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  901 VEKSEASRQEEQQ----RKALEAKAATFEKQVLQLQASHKESE-EALQKRLEEVTRELCraqtshANLRADAEKAQEQQQ 975
Cdd:COG5022   877 VELAERQLQELKIdvksISSLKLVNLELESEIIELKKSLSSDLiENLEFKTELIARLKK------LLNNIDLEEGPSIEY 950

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  976 RVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQ--DTQASHAEANQQQTRLKELES 1053
Cdd:COG5022   951 VKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQygALQESTKQLKELPVEVAELQS 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1054 QVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAER----ACEEKLRSLTQAKEESEKQLHLAEAQTKETLLAL 1129
Cdd:COG5022  1031 ASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRrensLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVK 1110
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 211-569 1.73e-05

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 49.23  E-value: 1.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  211 GEGAQNQGKKGEGAqnqakkGEGAQNQAKKGEGAQNQGKKGEGAQN---QAKKGEGGQNQAKKGE-GAQNQGKKGEGAQN 286
Cdd:cd21118    24 GEGTGAGESAGHGL------GDAISHGIGEAVGQGAKEAASSGIQNalgQGHGEEGGSTLGSRGDvFEHRLGEAARSLGN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  287 QGKK-GEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAqNQAKKGEGGQNQAKKGEGAQNQAKKGeGAQ 365
Cdd:cd21118    98 AGNEiGRQAEDIIRHGVDAVHNSWQGSGGHGAYGSQGGPGVQGHGIPGG-TGGPWASGGNYGTNSLGGSVGQGGNG-GPL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  366 NQAKKGEGVQNQAKKGVEGAQNQgKKGEANQNQAKKGEGGQNQTKKgegpqnqgkkgeaaqkqdkkiEGAQNQGKKPEGT 445
Cdd:cd21118   176 NYGTNSQGAVAQPGYGTVRGNNQ-NSGCTNPPPSGSHESFSNSGGS---------------------SSSGSSGSQGSHG 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  446 SNQGKKGEGAQNQGKKGEGAQNQGKKG-EGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGeGAQNQGKKGEG 524
Cdd:cd21118   234 SNGQGSSGSSGGQGNGGNNGSSSSNSGnSGGSNGGSSGNSGSGSGGSSSGGSNGWGGSSSSGGSGGSG-GGNKPECNNPG 312

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 568918950  525 PQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQS 569
Cdd:cd21118   313 NDVRMAGGGGSQGSKESSGSHGSNGGNGQAEAVGGLNTLNSDAST 357
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 361-645 2.51e-05

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 48.46  E-value: 2.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  361 GEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQ----TKKGEGPQNQGKKGEAAQ-------KQD 429
Cdd:cd21118    24 GEGTGAGESAGHGLGDAISHGIGEAVGQGAKEAASSGIQNALGQGHGEeggsTLGSRGDVFEHRLGEAARslgnagnEIG 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  430 KKIEGAQNQGKKPEGTSNQGKKGEGAQN-QGKKGEGAQ-----NQGKKGEGAQNQGKKGEGAQNQGKKGeGAQNQGKKGE 503
Cdd:cd21118   104 RQAEDIIRHGVDAVHNSWQGSGGHGAYGsQGGPGVQGHgipggTGGPWASGGNYGTNSLGGSVGQGGNG-GPLNYGTNSQ 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  504 GAQNQ-GKKGEGAQNQ--------GKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEG 574
Cdd:cd21118   183 GAVAQpGYGTVRGNNQnsgctnppPSGSHESFSNSGGSSSSGSSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSGNS 262

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568918950  575 TQNQGkkgDGNPNQG--KKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGS 645
Cdd:cd21118   263 GGSNG---GSSGNSGsgSGGSSSGGSNGWGGSSSSGGSGGSGGGNKPECNNPGNDVRMAGGGGSQGSKESSGS 332
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 880-1416 2.63e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.81  E-value: 2.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   880 SKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTS 959
Cdd:TIGR00618  162 SKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQS 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   960 HANLRADAEKAQEQQQRVAELHsklqssevEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQA-QDTQASH 1038
Cdd:TIGR00618  242 HAYLTQKREAQEEQLKKQQLLK--------QLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIeQQAQRIH 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1039 AEANQQQTRLKELESQVSCLEKETSELKEA---MEQQKGKNNDLREKNWKAMEALALAERACE--EKLRSLTQAKEESEK 1113
Cdd:TIGR00618  314 TELQSKMRSRAKLLMKRAAHVKQQSSIEEQrrlLQTLHSQEIHIRDAHEVATSIREISCQQHTltQHIHTLQQQKTTLTQ 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1114 QLHLA---------EAQTKETLLALLPGL---------SISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMdiVLKLREA 1175
Cdd:TIGR00618  394 KLQSLckeldilqrEQATIDTRTSAFRDLqgqlahakkQQELQQRYAELCAAAITCTAQCEKLEKIHLQES--AQSLKER 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1176 EETQNSLQAECDQYRTILAETEG---MLKDLQKSVEEEERVWKAKV------GAAEEELHKSRVTVKHLEDIVEKLKGEL 1246
Cdd:TIGR00618  472 EQQLQTKEQIHLQETRKKAVVLArllELQEEPCPLCGSCIHPNPARqdidnpGPLTRRMQRGEQTYAQLETSEEDVYHQL 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1247 ESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAE 1326
Cdd:TIGR00618  552 TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVR 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1327 QTRRQKlTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQEL---LKTTQEQL 1403
Cdd:TIGR00618  632 LHLQQC-SQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqcQTLLRELE 710

                          570
                   ....*....|...
gi 568918950  1404 TKEKDTVKKLQEQ 1416
Cdd:TIGR00618  711 THIEEYDREFNEI 723
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 271-597 2.66e-05

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 48.46  E-value: 2.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  271 GEGAQNQGKKGEGAqnqgkkGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEG-AQNQSKKGEGAQNQAKKGEGGQNQAK 349
Cdd:cd21118    24 GEGTGAGESAGHGL------GDAISHGIGEAVGQGAKEAASSGIQNALGQGHGeEGGSTLGSRGDVFEHRLGEAARSLGN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  350 KGEGAQNQAKK--GEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGeaaqk 427
Cdd:cd21118    98 AGNEIGRQAEDiiRHGVDAVHNSWQGSGGHGAYGSQGGPGVQGHGIPGGTGGPWASGGNYGTNSLGGSVGQGGNG----- 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  428 qdkkieGAQNQGKKPEGTSNQGkkGEGAQNQGKKGEGAQNQGKKGegaqnqgkKGEGAQNQGKkGEGAQNQGKKGEGAQN 507
Cdd:cd21118   173 ------GPLNYGTNSQGAVAQP--GYGTVRGNNQNSGCTNPPPSG--------SHESFSNSGG-SSSSGSSGSQGSHGSN 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  508 QGKKGEGaqnQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKK--GEGTQNQGKKGDGN 585
Cdd:cd21118   236 GQGSSGS---SGGQGNGGNNGSSSSNSGNSGGSNGGSSGNSGSGSGGSSSGGSNGWGGSSSSGGsgGSGGGNKPECNNPG 312

                         330
                  ....*....|..
gi 568918950  586 PNQGKKGEGASN 597
Cdd:cd21118   313 NDVRMAGGGGSQ 324
Filament pfam00038
Intermediate filament protein;
826-1072 3.00e-05

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 47.61  E-value: 3.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   826 ASYRDHVKEVQQ----LQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQvESKQNTELAKLRQEL----SKVN 897
Cdd:pfam00038   14 ASYIDKVRFLEQqnklLETKISELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTVE-RARLQLELDNLRLAAedfrQKYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   898 KELVEKSEASRQEEQQRKALEakAATFEKQVLQLQASHKESEEALQKRL--EEVTRELCRAQTSHANLRADAEKAQEQQQ 975
Cdd:pfam00038   93 DELNLRTSAENDLVGLRKDLD--EATLARVDLEAKIESLKEELAFLKKNheEEVRELQAQVSDTQVNVEMDAARKLDLTS 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   976 RVAELHSK--------LQSSEVEVKSKCEELSSLHGQ----LKEARAENSQLTERIRSIEALLEA--GQAQDTQASHAEA 1041
Cdd:pfam00038  171 ALAEIRAQyeeiaaknREEAEEWYQSKLEELQQAAARngdaLRSAKEEITELRRTIQSLEIELQSlkKQKASLERQLAET 250

                          250       260       270
                   ....*....|....*....|....*....|..
gi 568918950  1042 NQQQTR-LKELESQVSCLEKETSELKEAMEQQ 1072
Cdd:pfam00038  251 EERYELqLADYQELISELEAELQETRQEMARQ 282
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 759-1422 3.10e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.80  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  759 ILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAsekakaaageakvkkQLVAREQEIAAvqaRMQASyRDHVKEVQ-- 836
Cdd:COG3096   282 ELSERALELRRELFGARRQLAEEQYRLVEMARELE---------------ELSARESDLEQ---DYQAA-SDHLNLVQta 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  837 -QLQGKIRTLQEQLENGPntqlARLQQENSILRDALNQATSQVESKQNTELA--KLRQELSKVNKELVEKSEASRQEEQQ 913
Cdd:COG3096   343 lRQQEKIERYQEDLEELT----ERLEEQEEVVEEAAEQLAEAEARLEAAEEEvdSLKSQLADYQQALDVQQTRAIQYQQA 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  914 RKALEaKAatfeKQVLQL----QASHKESEEALQKRLEEVTRELCRAQTShanlRADAEKAQEQQQRVAELHSKLqSSEV 989
Cdd:COG3096   419 VQALE-KA----RALCGLpdltPENAEDYLAAFRAKEQQATEEVLELEQK----LSVADAARRQFEKAYELVCKI-AGEV 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  990 E-----------------VKSKCEELSSLHGQLKEARaensQLTERIRSIEALLEA-GQAQDTQASHAE-----ANQQQT 1046
Cdd:COG3096   489 ErsqawqtarellrryrsQQALAQRLQQLRAQLAELE----QRLRQQQNAERLLEEfCQRIGQQLDAAEeleelLAELEA 564

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1047 RLKELESQVSCLEKETSELKEAMEQQKGKNNDLREK--NW-KAMEALALAERACEEKL---RSLTQAKE---ESEKQLHL 1117
Cdd:COG3096   565 QLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARapAWlAAQDALERLREQSGEALadsQEVTAAMQqllEREREATV 644

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1118 AE---AQTKETLLALLPGLSISAHQNYAEwLQEFKEK-GSELLKK---------PPTLE----PSMD--IVLKLREAEET 1178
Cdd:COG3096   645 ERdelAARKQALESQIERLSQPGGAEDPR-LLALAERlGGVLLSEiyddvtledAPYFSalygPARHaiVVPDLSAVKEQ 723

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1179 QNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWkakVGAAEEELHKSRVTVKHL------EDIVEKLKGELESSDQ- 1251
Cdd:COG3096   724 LAGLEDCPEDLYLIEGDPDSFDDSVFDAEELEDAVV---VKLSDRQWRYSRFPEVPLfgraarEKRLEELRAERDELAEq 800

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1252 -------VREH---TSHLEAELEKHMAAASAEcqNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLE---- 1317
Cdd:COG3096   801 yakasfdVQKLqrlHQAFSQFVGGHLAVAFAP--DPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQllnk 878

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1318 -RTEATLEAEQT---RRQKLTAEFEEAQRTACRIQEELEKLRAAGPLES---SGKEEITQLKERLEKEKRLTSDLGRAAI 1390
Cdd:COG3096   879 lLPQANLLADETladRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAvlqSDPEQFEQLQADYLQAKEQQRRLKQQIF 958

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|
gi 568918950 1391 KLQELLKT--------TQEQLTKEKDTVKKLQEQLGKAED 1422
Cdd:COG3096   959 ALSEVVQRrphfsyedAVGLLGENSDLNEKLRARLEQAEE 998
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 940-1212 3.26e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.80  E-value: 3.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  940 EALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVE-VKSKCEELSSLHGQLKEARAENSQLTER 1018
Cdd:COG3096   839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADEtLADRLEELREELDAAQEAQAFIQQHGKA 918

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1019 IRSIEALLEAGQA--QDTQASHAEANQQQTRLKELESQVSCLEkETSELKEAM-----EQQKGKNNDLREKnwkameala 1091
Cdd:COG3096   919 LAQLEPLVAVLQSdpEQFEQLQADYLQAKEQQRRLKQQIFALS-EVVQRRPHFsyedaVGLLGENSDLNEK--------- 988

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1092 laeraCEEKLRSLTQAKEESEKQLHLAEAQTKETlLALLPGLSiSAHQNYAEWLQEFKEKGSEL-LKKPPTLEPSMDIVL 1170
Cdd:COG3096   989 -----LRARLEQAEEARREAREQLRQAQAQYSQY-NQVLASLK-SSRDAKQQTLQELEQELEELgVQADAEAEERARIRR 1061

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 568918950 1171 KLREAEETQNslQAECDQYRTILAETEGMLKDLQKSVEEEER 1212
Cdd:COG3096  1062 DELHEELSQN--RSRRSQLEKQLTRCEAEMDSLQKRLRKAER 1101
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1235-1422 4.42e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 4.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1235 LEDIVEKLKGELESSDQVREHtsHLEAELEKHMAaasaECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKT 1314
Cdd:COG2433   382 LEELIEKELPEEEPEAEREKE--HEERELTEEEE----EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARS 455

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1315 QlERTEATLEAEQTRRQKLTAefeeaqrtacRIQEELEKLRaagplessgkEEITQLKERLEKEKRL-TSDLGRAAIKLQ 1393
Cdd:COG2433   456 E-ERREIRKDREISRLDREIE----------RLERELEEER----------ERIEELKRKLERLKELwKLEHSGELVPVK 514

                         170       180
                  ....*....|....*....|....*....
gi 568918950 1394 ELlkttqEQLTKEkdTVKKLQEQLGKAED 1422
Cdd:COG2433   515 VV-----EKFTKE--AIRRLEEEYGLKEG 536
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
748-1081 4.52e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 4.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  748 HKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAR----EQEIAAVQAR 823
Cdd:PRK03918  377 LKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGreltEEHRKELLEE 456

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  824 MQASYRDHVKEVQQLQGKIRTLQEQLENGPNTqlarLQQENSILRdalnqatsqvESKQNTELAKLRQELSKVNKElvek 903
Cdd:PRK03918  457 YTAELKRIEKELKEIEEKERKLRKELRELEKV----LKKESELIK----------LKELAEQLKELEEKLKKYNLE---- 518

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  904 sEASRQEEQQRKaLEAKAATFEKQVLQLqASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEK-----AQEQQQRVA 978
Cdd:PRK03918  519 -ELEKKAEEYEK-LKEKLIKLKGEIKSL-KKELEKLEELKKKLAELEKKLDELEEELAELLKELEElgfesVEELEERLK 595

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  979 ELHS------KLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQqqtRLKELE 1052
Cdd:PRK03918  596 ELEPfyneylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELRE---EYLELS 672

                         330       340
                  ....*....|....*....|....*....
gi 568918950 1053 SQVSCLEKETSELKEAMEQQKGKNNDLRE 1081
Cdd:PRK03918  673 RELAGLRAELEELEKRREEIKKTLEKLKE 701
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1058-1421 4.64e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 4.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1058 LEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLpglSISA 1137
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE---KLEK 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1138 HQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAE-----TEGMLKDLQKSVEEEER 1212
Cdd:COG4717   124 LLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEElleqlSLATEEELQDLAEELEE 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1213 VWKaKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVRE-------------------HTSHLEAELEKHMAAASAE 1273
Cdd:COG4717   204 LQQ-RLAELEEELEEAQEELEELEEELEQLENELEAAALEERlkearlllliaaallallgLGGSLLSLILTIAGVLFLV 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1274 CQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLER------------TEATLEAEQTRRQKLTAEFEEAQ 1341
Cdd:COG4717   283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAlglppdlspeelLELLDRIEELQELLREAEELEEE 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1342 RTACRIQEELEKLRAAGPLES---------------SGKEEITQLKERLEKEKRLTSDLGRAAIK--LQELLKTTQEQLT 1404
Cdd:COG4717   363 LQLEELEQEIAALLAEAGVEDeeelraaleqaeeyqELKEELEELEEQLEELLGELEELLEALDEeeLEEELEELEEELE 442

                         410
                  ....*....|....*..
gi 568918950 1405 KEKDTVKKLQEQLGKAE 1421
Cdd:COG4717   443 ELEEELEELREELAELE 459
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 834-1378 4.77e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 4.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   834 EVQQLQGKIRTLQEQLENGPNT---QLARLQQENSILRDALNQATSQVESKqnteLAKLRQELSKVNKELVEkseaSRQE 910
Cdd:pfam15921  293 QANSIQSQLEIIQEQARNQNSMymrQLSDLESTVSQLRSELREAKRMYEDK----IEELEKQLVLANSELTE----ARTE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   911 EQQrkaLEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVE 990
Cdd:pfam15921  365 RDQ---FSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   991 VKSKCE-ELSSLHGQlKEARAENSQLTERIRSIEALLE------AGQAQDTQASHAEANQQQTRLKELESQVSCLEKETS 1063
Cdd:pfam15921  442 CQGQMErQMAAIQGK-NESLEKVSSLTAQLESTKEMLRkvveelTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1064 ELKEAM-----EQQKGKNNDLREKNWKA-MEALALaERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISA 1137
Cdd:pfam15921  521 KLRSRVdlklqELQHLKNEGDHLRNVQTeCEALKL-QMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEI 599

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1138 HQNYAEwLQEFK-------EKGSELLKKPPTLE-PSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEE 1209
Cdd:pfam15921  600 NDRRLE-LQEFKilkdkkdAKIRELEARVSDLElEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEV 678

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1210 EERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLL 1289
Cdd:pfam15921  679 LKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMT 758

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1290 ESQSQLDEAKSEAQKQSDELALLKTQlerteatleaeqtrRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEIT 1369
Cdd:pfam15921  759 NANKEKHFLKEEKNKLSQELSTVATE--------------KNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQ 824


                   ....*....
gi 568918950  1370 QLKERLEKE 1378
Cdd:pfam15921  825 DIIQRQEQE 833
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1123-1360 4.84e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 4.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1123 KETLLALLPGLSISAHQNYAEWLqeFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKD 1202
Cdd:COG4717    36 KSTLLAFIRAMLLERLEKEADEL--FKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEE 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1203 LQKSVEEEERVWKAKvgAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAEcqnyakeva 1282
Cdd:COG4717   114 LREELEKLEKLLQLL--PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEEL--------- 182

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568918950 1283 gLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTAcRIQEELEKLRAAGPL 1360
Cdd:COG4717   183 -LEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE-RLKEARLLLLIAAAL 258
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 757-1415 4.94e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 4.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   757 VAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEmASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQ 836
Cdd:pfam02463  347 LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL-ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEK 425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   837 QLQGKIRTLQEQLENGPNTQLArLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKA 916
Cdd:pfam02463  426 KEELEILEEEEESIELKQGKLT-EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESK 504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   917 LEAKAATFEKQVLQLQASHKESEEALQKRLEEVTrELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCE 996
Cdd:pfam02463  505 ARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAV-ENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLL 583

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   997 ELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELES------------QVSCLEKETSE 1064
Cdd:pfam02463  584 IPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESakakesglrkgvSLEEGLAEKSE 663

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1065 LKEAMEQQKGKNNDLREKNWKA-MEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQNYAE 1143
Cdd:pfam02463  664 VKASLSELTKELLEIQELQEKAeSELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1144 WLQEFKEKGSELLKKPPTLEP------SMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLK-------DLQKSVEEE 1210
Cdd:pfam02463  744 KIDEEEEEEEKSRLKKEEKEEekselsLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEeelkeeaELLEEEQLL 823

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1211 ERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHmaaaSAECQNYAKEVAGLRQLLLE 1290
Cdd:pfam02463  824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL----EEQKLKDELESKEEKEKEEK 899

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1291 SQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEITQ 1370
Cdd:pfam02463  900 KELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMA 979

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 568918950  1371 LKERLEKEKRLTSDLGRAAIKLQEllKTTQEQLTKEKDTVKKLQE 1415
Cdd:pfam02463  980 IEEFEEKEERYNKDELEKERLEEE--KKKLIRAIIEETCQRLKEF 1022
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 845-1349 6.13e-05

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 47.44  E-value: 6.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   845 LQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNK----ELVEKSEASRQEEQQRKALEAK 920
Cdd:pfam07111  130 VRKNLEEGSQRELEEIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETkragEAKQLAEAQKEAELLRKQLSKT 209

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   921 AATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQ--TSHANLRADAEKAQEQ----QQRVAELHSKLQSSEVEVKSK 994
Cdd:pfam07111  210 QEELEAQVTLVESLRKYVGEQVPPEVHSQTWELERQEllDTMQHLQEDRADLQATvellQVRVQSLTHMLALQEEELTRK 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   995 CEELSSLHGQLkeARAENSQLTERIRSIEALLEAGQAQDTQASHAeANQQQTRLKELESQVSCLEKETSELKEAM----- 1069
Cdd:pfam07111  290 IQPSDSLEPEF--PKKCRSLLNRWREKVFALMVQLKAQDLEHRDS-VKQLRGQVAELQEQVTSQSQEQAILQRALqdkaa 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1070 --EQQKGKNNDLREKNWKAMEALALAER---ACEEKLRSLTQAKEESEKQLHLAEAQTKETLlALLPGLS---------- 1134
Cdd:pfam07111  367 evEVERMSAKGLQMELSRAQEARRRQQQqtaSAEEQLKFVVNAMSSTQIWLETTMTRVEQAV-ARIPSLSnrlsyavrkv 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1135 --ISAHQNYAEWLQEFKEKGSELLKKPPTLEpsMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDlqkSVEEEER 1212
Cdd:pfam07111  446 htIKGLMARKVALAQLRQESCPPPPPAPPVD--ADLSLELEQLREERNRLDAELQLSAHLIQQEVGRARE---QGEAERQ 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1213 VWKAKVGAAEEELHKSRvtvKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEV-AGLRQLLLES 1291
Cdd:pfam07111  521 QLSEVAQQLEQELQRAQ---ESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVeTRLREQLSDT 597

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 568918950  1292 QSQLDEAKSEAQKQSdeLALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQE 1349
Cdd:pfam07111  598 KRRLNEARREQAKAV--VSLRQIQHRATQEKERNQELRRLQDEARKEEGQRLARRVQE 653
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 755-1419 8.11e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 8.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   755 DPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAkvkkQLVAREQEIAAVQARMQ---ASYRDH 831
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE----EYAELKEELEDLRAELEevdKEFAET 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   832 VKEVQQLQGKIRTLQEQLENgpntqlarLQQENSILRDALNQATSQVESKQNtELAKLRQELSKVNKELVEKSEASRQEE 911
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINE--------LKRELDRLQEELQRLSEELADLNA-AIAGIEAKINELEEEKEDKALEIKKQE 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   912 QQRKALEAKAATFEKQVLQLqashKESEEALQKRLEEVTRELCR--AQTSHANLRADAEKAQEQQQR---------VAEL 980
Cdd:TIGR02169  455 WKLEQLAADLSKYEQELYDL----KEEYDRVEKELSKLQRELAEaeAQARASEERVRGGRAVEEVLKasiqgvhgtVAQL 530

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   981 HS---------------KLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTeRIRSIEALLEAGQA-------------- 1031
Cdd:TIGR02169  531 GSvgeryataievaagnRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLN-KMRDERRDLSILSEdgvigfavdlvefd 609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1032 -----------QDT----QASHAEANQQQTRLKELESQVscLEKETSELKEAMEQQKGKNNDLREKNwkamEALALAER- 1095
Cdd:TIGR02169  610 pkyepafkyvfGDTlvveDIEAARRLMGKYRMVTLEGEL--FEKSGAMTGGSRAPRGGILFSRSEPA----ELQRLRERl 683

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1096 -ACEEKLRSLTQAKEESEKQLHLAEAQTKETllallpGLSISAHQNYAEWLQEFKEKGSELLKKpptLEPSMDIVLKLRE 1174
Cdd:TIGR02169  684 eGLKRELSSLQSELRRIENRLDELSQELSDA------SRKIGEIEKEIEQLEQEEEKLKERLEE---LEEDLSSLEQEIE 754

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1175 AEET-QNSLQAECDQYRTILAETEGMLKDLQKS---------------VEEEERVWKAKVGAAEEELHKSRVTVKHLEDI 1238
Cdd:TIGR02169  755 NVKSeLKELEARIEELEEDLHKLEEALNDLEARlshsripeiqaelskLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE 834

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1239 VEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLER 1318
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEK 914

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1319 TEATLEAEQTRRQKLTAEFEEAQRTACRIQEEleklraagPLESSGKEEITQLKERLEKEKRLTSDLGRAAI-------K 1391
Cdd:TIGR02169  915 KRKRLSELKAKLEALEEELSEIEDPKGEDEEI--------PEEELSLEDVQAELQRVEEEIRALEPVNMLAIqeyeevlK 986

                          730       740
                   ....*....|....*....|....*...
gi 568918950  1392 LQELLKTTQEQLTKEKDTVKKLQEQLGK 1419
Cdd:TIGR02169  987 RLDELKEKRAKLEEERKAILERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1167-1428 8.32e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 8.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1167 DIVLKLREAEETQNSLQAEcdQYRTILAETEGMLKDLQKSVEEEERvwkaKVGAAEEELHKSRVTVKHLEDIVEKLKGEl 1246
Cdd:TIGR02169  215 ALLKEKREYEGYELLKEKE--ALERQKEAIERQLASLEEELEKLTE----EISELEKRLEEIEQLLEELNKKIKDLGEE- 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1247 eSSDQVREHTSHLEAELEK---HMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATL 1323
Cdd:TIGR02169  288 -EQLRVKEKIGELEAEIASlerSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1324 EAEQTRRQKLTAEFEEAQRTACRIQEELEKL-RAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQEL------- 1395
Cdd:TIGR02169  367 EDLRAELEEVDKEFAETRDELKDYREKLEKLkREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELeeekedk 446

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 568918950  1396 ----------LKTTQEQLTKEKDTVKKLQEQLGKAEDGSSSKE 1428
Cdd:TIGR02169  447 aleikkqewkLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
942-1423 9.02e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 9.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  942 LQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAElhsklqSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRS 1021
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAE------EKEEEYAELQEELEELEEELEELEAELEELREELEK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1022 IEALLEAgqaqdtQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREknwkamealalAERACEEKL 1101
Cdd:COG4717   121 LEKLLQL------LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAE-----------LQEELEELL 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1102 RSLTQAKEESEKQLhlaeAQTKETLLAllpglsisAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNS 1181
Cdd:COG4717   184 EQLSLATEEELQDL----AEELEELQQ--------RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLL 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1182 LQAEcdqyrTILAETEGMLKDLQKSVEEEERVWKAKVG-AAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLe 1260
Cdd:COG4717   252 LLIA-----AALLALLGLGGSLLSLILTIAGVLFLVLGlLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELL- 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1261 AELEKHMAAASAECQNYAKEVAGLRQLLlesqSQLDEAKSEAQKQSDElALLKTQLERTEATLEAEQTRRQKLTAEFEEA 1340
Cdd:COG4717   326 AALGLPPDLSPEELLELLDRIEELQELL----REAEELEEELQLEELE-QEIAALLAEAGVEDEEELRAALEQAEEYQEL 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1341 QRTACRIQEELEKLrAAGPLESSGKEEITQLKERLEKekrltsdlgraaikLQELLKTTQEQLTKEKDTVKKLQEQLGKA 1420
Cdd:COG4717   401 KEELEELEEQLEEL-LGELEELLEALDEEELEEELEE--------------LEEELEELEEELEELREELAELEAELEQL 465


                  ...
gi 568918950 1421 EDG 1423
Cdd:COG4717   466 EED 468
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 837-1065 9.67e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.81  E-value: 9.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   837 QLQGKIRTLQE--QLENGPNTQLARLQQENSILRDALNQATSQVESK---QNTELAKLRQELSKVNKELVEKSEASRQEE 911
Cdd:pfam07888   35 RLEECLQERAEllQAQEAANRQREKEKERYKRDREQWERQRRELESRvaeLKEELRQSREKHEELEEKYKELSASSEELS 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   912 QQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRadaekaqEQQQRVAELHSKLQSSEVEV 991
Cdd:pfam07888  115 EEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRK-------EEEAERKQLQAKLQQTEEEL 187

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568918950   992 KSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQ--ASHAEANQQQTRLKELESQVSCLEKETSEL 1065
Cdd:pfam07888  188 RSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAEneALLEELRSLQERLNASERKVEGLGEELSSM 263
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 931-1421 1.24e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.89  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   931 LQASHKESEEALQK--RLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAelhsklQSSEVEVKSKCEELSSLHGQLKEA 1008
Cdd:TIGR00618  158 LKAKSKEKKELLMNlfPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLT------LCTPCMPDTYHERKQVLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1009 RAENSQLTERIRSIEALLEAGQAQDTQasHAEANQQQTRLKELESQvsclEKETSELKEAMEQQKGKNNDLREKNWKAME 1088
Cdd:TIGR00618  232 REALQQTQQSHAYLTQKREAQEEQLKK--QQLLKQLRARIEELRAQ----EAVLEETQERINRARKAAPLAAHIKAVTQI 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1089 ALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLsISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDI 1168
Cdd:TIGR00618  306 EQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTL-HSQEIHIRDAHEVATSIREISCQQHTLTQHIHTL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1169 VLKLREAEETQNSLQAECDQYR----TILAET------EGMLKDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDI 1238
Cdd:TIGR00618  385 QQQKTTLTQKLQSLCKELDILQreqaTIDTRTsafrdlQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQES 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1239 VEKLKGELESSDQVREHTshlEAELEKHmaaasAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLER 1318
Cdd:TIGR00618  465 AQSLKEREQQLQTKEQIH---LQETRKK-----AVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQT 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1319 TEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKT 1398
Cdd:TIGR00618  537 YAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHA 616

                          490       500
                   ....*....|....*....|...
gi 568918950  1399 TQEQLTKEKDTVKKLQEQLGKAE 1421
Cdd:TIGR00618  617 LLRKLQPEQDLQDVRLHLQQCSQ 639
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 763-1420 1.55e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.26  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   763 QLEEKEKLLAteQEDAAVAKSKLRELNKE---MASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQQLQ 839
Cdd:pfam15921   99 ELHEKQKFYL--RQSVIDLQTKLQEMQMErdaMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLR 176

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   840 G----------KIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELveksEASRQ 909
Cdd:pfam15921  177 KmmlshegvlqEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQL----EALKS 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   910 EEQQRkaLEAKAATFEKQVLQLQASHkesEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSev 989
Cdd:pfam15921  253 ESQNK--IELLLQQHQDRIEQLISEH---EVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLEST-- 325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   990 evkskceeLSSLHGQLKEARaenSQLTERIRSIEALLEAGQAQDTQAsHAEANQQQTRLKELESQVSCLEKETSELKEAM 1069
Cdd:pfam15921  326 --------VSQLRSELREAK---RMYEDKIEELEKQLVLANSELTEA-RTERDQFSQESGNLDDQLQKLLADLHKREKEL 393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1070 EQQKGKNNDLREKNWKamealalaeraceeklRSLTQAKEESEKQLHLAEAQTKETLLALLPglsisahqnyAEWLQEFK 1149
Cdd:pfam15921  394 SLEKEQNKRLWDRDTG----------------NSITIDHLRRELDDRNMEVQRLEALLKAMK----------SECQGQME 447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1150 EKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKvgAAEEELHKSR 1229
Cdd:pfam15921  448 RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAT--NAEITKLRSR 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1230 VTVKHLEdiVEKLKGElessdqvREHTSHLEAELEK---HMAAASAECQNYAKEVAGLRQL----------LLESQSQLD 1296
Cdd:pfam15921  526 VDLKLQE--LQHLKNE-------GDHLRNVQTECEAlklQMAEKDKVIEILRQQIENMTQLvgqhgrtagaMQVEKAQLE 596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1297 EAKSEAQKQSDELALLK----TQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAgplESSGKEEITQLK 1372
Cdd:pfam15921  597 KEINDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNE---VKTSRNELNSLS 673

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568918950  1373 ERLEKEKR----LTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKA 1420
Cdd:pfam15921  674 EDYEVLKRnfrnKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHA 725
mukB PRK04863
chromosome partition protein MukB;
940-1212 1.76e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  940 EALQKRLEEVTRELCRAQTSHANLRADAEKAQ---EQQQRVAELHSKLQ---SSEVEVKSKCEELSSLHGQLKEARAENS 1013
Cdd:PRK04863  782 AAREKRIEQLRAEREELAERYATLSFDVQKLQrlhQAFSRFIGSHLAVAfeaDPEAELRQLNRRRVELERALADHESQEQ 861

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1014 QLTERIRSIEALL----------------------EAGQAQDTQASHAEA--NQQQTRLKELESQVSCLEKETSE---LK 1066
Cdd:PRK04863  862 QQRSQLEQAKEGLsalnrllprlnlladetladrvEEIREQLDEAEEAKRfvQQHGNALAQLEPIVSVLQSDPEQfeqLK 941

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1067 EAMEQQKGKNNDLReknwkaMEALALAE------------------------RACEEKLRSLTQAKEESEKQLHLAEAQ- 1121
Cdd:PRK04863  942 QDYQQAQQTQRDAK------QQAFALTEvvqrrahfsyedaaemlaknsdlnEKLRQRLEQAEQERTRAREQLRQAQAQl 1015

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1122 --TKETLLALlpglsISAHQNYAEWLQEFKEkgsELLKKPPTLEPSMDIVLKLREaEETQNSL---QAECDQYRTILAET 1196
Cdd:PRK04863 1016 aqYNQVLASL-----KSSYDAKRQMLQELKQ---ELQDLGVPADSGAEERARARR-DELHARLsanRSRRNQLEKQLTFC 1086

                         330
                  ....*....|....*.
gi 568918950 1197 EGMLKDLQKSVEEEER 1212
Cdd:PRK04863 1087 EAEMDNLTKKLRKLER 1102
PRK11281 PRK11281
mechanosensitive channel MscK;
1240-1426 1.98e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 46.06  E-value: 1.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1240 EKLKGELESSD-QVREHTSHLEAeLEKhmAAASAECQNYAK-EVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLE 1317
Cdd:PRK11281   83 EQLKQQLAQAPaKLRQAQAELEA-LKD--DNDEETRETLSTlSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPE 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1318 RTEATLEAEQTRRQKLT----------AEFEEAQRTacRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSD--- 1384
Cdd:PRK11281  160 RAQAALYANSQRLQQIRnllkggkvggKALRPSQRV--LLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTAriq 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 568918950 1385 -LGRAAIKLQELLktTQEQLTKEKDTVKKLQEQLGKAEDGSSS 1426
Cdd:PRK11281  238 rLEHQLQLLQEAI--NSKRLTLSEKTVQEAQSQDEAARIQANP 278
Gag_spuma pfam03276
Spumavirus gag protein;
207-347 2.14e-04

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 45.89  E-value: 2.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   207 QAKKGEGAQNQGKKGEGAQNQAKKGEGAQ----NQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQGkkge 282
Cdd:pfam03276  480 QIRASRGPGPGPSAGEGRGGPANEGRGGPcnagGGNDCGANGQNDGGENIQNGGQELRSQGGQNLRSGGGQGQRWG---- 555

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568918950   283 gaQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGegaqNQSKKGEGAQNQAKKGEGGQNQ 347
Cdd:pfam03276  556 --EGRGNRENENTENSEQRPREIQAGSGRPGNAGQGVKG----AAGQGGKGAAGRGGRGNGAGDQ 614
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
750-1130 2.35e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 2.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  750 ATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAkvkkQLVAREQEIAAVQARMQASYR 829
Cdd:COG4913   333 RGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRA----EAAALLEALEEELEALEEALA 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  830 DHVKEVQQLQGKIRTLQ---EQLENGPNTQLARLQQensiLRDALNQATS-------------QVESKQNT--------- 884
Cdd:COG4913   409 EAEAALRDLRRELRELEaeiASLERRKSNIPARLLA----LRDALAEALGldeaelpfvgeliEVRPEEERwrgaiervl 484

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  885 ---------ELAKLRQELSKVNKE-----LV-EKSEASRQEEQQRKA--------LEAKAATFE---KQVLQLQASHK-- 936
Cdd:COG4913   485 ggfaltllvPPEHYAAALRWVNRLhlrgrLVyERVRTGLPDPERPRLdpdslagkLDFKPHPFRawlEAELGRRFDYVcv 564

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  937 ESEEALQKRLEEVTRElcrAQTSHANLRA--DAEKAQEQQ--------QRVAELHSKLQSSEvevkskcEELSSLHGQLK 1006
Cdd:COG4913   565 DSPEELRRHPRAITRA---GQVKGNGTRHekDDRRRIRSRyvlgfdnrAKLAALEAELAELE-------EELAEAEERLE 634

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1007 EARAENSQLTERIRSIEALLEAGQAQD----TQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREK 1082
Cdd:COG4913   635 ALEAELDALQERREALQRLAEYSWDEIdvasAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGE 714

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 568918950 1083 nwkamealalaERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALL 1130
Cdd:COG4913   715 -----------IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751
mukB PRK04863
chromosome partition protein MukB;
814-1074 3.10e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 3.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  814 EQEIAAVQARMQASYR---DHVKEVQQLQGKIRTLQEQLengpnTQLARLQQENSIL---------------RDALNQAT 875
Cdd:PRK04863  836 EAELRQLNRRRVELERalaDHESQEQQQRSQLEQAKEGL-----SALNRLLPRLNLLadetladrveeireqLDEAEEAK 910

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  876 SQVESKQNTeLAKLRQELSKVN---------KELVEKSEASRQEEQQR----KALEAKAATFE-KQVLQLQASHKESEEA 941
Cdd:PRK04863  911 RFVQQHGNA-LAQLEPIVSVLQsdpeqfeqlKQDYQQAQQTQRDAKQQafalTEVVQRRAHFSyEDAAEMLAKNSDLNEK 989

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  942 LQKRLEEVTRELCRAQTShanLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSL-----HGQLKEARAENSQLT 1016
Cdd:PRK04863  990 LRQRLEQAEQERTRAREQ---LRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgvpadSGAEERARARRDELH 1066

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1017 ERIRsiealleagqAQDTQASHAEANQ--QQTRLKELESQVSCLEKETSELKEAMEQQKG 1074
Cdd:PRK04863 1067 ARLS----------ANRSRRNQLEKQLtfCEAEMDNLTKKLRKLERDYHEMREQVVNAKA 1116
Gag_spuma pfam03276
Spumavirus gag protein;
449-598 3.79e-04

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 45.12  E-value: 3.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   449 GKKGEGAQNQGKKGEG-AQNQGKKGEGAQNQGKKGE-GAQNQGKKGEGAQNQGkkGEGAQNQGK--KGEGAQNQGKKGEG 524
Cdd:pfam03276  473 GLAARGPQIRASRGPGpGPSAGEGRGGPANEGRGGPcNAGGGNDCGANGQNDG--GENIQNGGQelRSQGGQNLRSGGGQ 550

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568918950   525 PQNQakkgegAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGegtqNQGKKGDGNPNQGKKGEGASNQ 598
Cdd:pfam03276  551 GQRW------GEGRGNRENENTENSEQRPREIQAGSGRPGNAGQGVKG----AAGQGGKGAAGRGGRGNGAGDQ 614
PRK12704 PRK12704
phosphodiesterase; Provisional
 1260-1407 4.39e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 4.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1260 EAELEKHMAAASAECQNYAKEVaglrqlLLESQSQLDEAKSEAQKQS----DELALLKTQLERTEATLEAEQTRRQKLTA 1335
Cdd:PRK12704   37 EEEAKRILEEAKKEAEAIKKEA------LLEAKEEIHKLRNEFEKELrerrNELQKLEKRLLQKEENLDRKLELLEKREE 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568918950 1336 EFEEAQRTACRIQEELEKlraagpLESSGKEEITQLKERLEKEKRLTSDLGRaaiklQELLKTTQEQLTKEK 1407
Cdd:PRK12704  111 ELEKKEKELEQKQQELEK------KEEELEELIEEQLQELERISGLTAEEAK-----EILLEKVEEEARHEA 171
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1191-1416 6.79e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 6.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1191 TILAETEGMLKD-LQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAa 1269
Cdd:COG4717    38 TLLAFIRAMLLErLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELRE- 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1270 asaecqnyakevaglRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQE 1349
Cdd:COG4717   117 ---------------ELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEE 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568918950 1350 ELEKLRAAGplessgKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQ 1416
Cdd:COG4717   182 LLEQLSLAT------EEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE 242
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 781-1420 6.98e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.40  E-value: 6.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   781 AKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRdhvkEVQQLQGKIRTLQEQLENgPNTQLARL 860
Cdd:pfam01576  378 AKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESER----QRAELAEKLSKLQSELES-VSSLLNEA 452

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   861 QQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAAtFEKQVLQLQASHKEsee 940
Cdd:pfam01576  453 EGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRN-VERQLSTLQAQLSD--- 528

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   941 aLQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKskcEELSSLHGQLKEARAENSQLTERIR 1020
Cdd:pfam01576  529 -MKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQ---QELDDLLVDLDHQRQLVSNLEKKQK 604

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1021 SIEALL------EAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDL---REKNWKAMEALA 1091
Cdd:pfam01576  605 KFDQMLaeekaiSARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLvssKDDVGKNVHELE 684

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1092 LAERACEEKLRSLTQAKEESEKQLHLAEaQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLK 1171
Cdd:pfam01576  685 RSKRALEQQVEEMKTQLEELEDELQATE-DAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERK 763

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1172 LREA--------EETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELHKSRVT---VKHLEDIVE 1240
Cdd:pfam01576  764 QRAQavaakkklELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESekkLKNLEAELL 843

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1241 KLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTE 1320
Cdd:pfam01576  844 QLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLT 923

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1321 ATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLE-----SSGKEEITQLKERLEKEKRLTSDLGRAAIKLQEL 1395
Cdd:pfam01576  924 TELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKfkssiAALEAKIAQLEEQLEQESRERQAANKLVRRTEKK 1003

                          650       660
                   ....*....|....*....|....*
gi 568918950  1396 LKTTQEQLTKEKDTVKKLQEQLGKA 1420
Cdd:pfam01576 1004 LKEVLLQVEDERRHADQYKDQAEKG 1028
Tropomyosin pfam00261
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ...
 833-1081 7.63e-04

Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.


Pssm-ID: 459736 [Multi-domain]  Cd Length: 235  Bit Score: 42.71  E-value: 7.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   833 KEVQQLQGKIRTLQEQLEngpnTQLARLQQENSILRDALNQATSQVESKQNTE--LAKLRQELSKVNKELVEKSEASRQE 910
Cdd:pfam00261    1 KKMQQIKEELDEAEERLK----EAMKKLEEAEKRAEKAEAEVAALNRRIQLLEeeLERTEERLAEALEKLEEAEKAADES 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   911 EQQRKALEAKAATFEKQVLQLQASHKES---EEALQKRLEEVTRELcraqtshANLRADAEKAQEqqqRVAELHSKLQSS 987
Cdd:pfam00261   77 ERGRKVLENRALKDEEKMEILEAQLKEAkeiAEEADRKYEEVARKL-------VVVEGDLERAEE---RAELAESKIVEL 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   988 EVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEagqaqdtqashaeanQQQTRLKELESQVSCLEKETSELKE 1067
Cdd:pfam00261  147 EEELKVVGNNLKSLEASEEKASEREDKYEEQIRFLTEKLK---------------EAETRAEFAERSVQKLEKEVDRLED 211

                          250
                   ....*....|....
gi 568918950  1068 AMEQQKGKNNDLRE 1081
Cdd:pfam00261  212 ELEAEKEKYKAISE 225
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 942-1376 8.79e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 43.96  E-value: 8.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   942 LQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKlQSSEVEVKskceeLSSLHGQLKEARAENSQLTERIRS 1021
Cdd:pfam05557    7 SKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESD-RNQELQKR-----IRLLEKREAEAEEALREQAELNRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1022 IEALLEAgqaqdtqaSHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEkL 1101
Cdd:pfam05557   81 KKKYLEA--------LNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASE-A 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1102 RSLTQAKEESEKQLHLAEAQTKETLLALlpglsisahQNYAEWLQEFKEKGSELLKKP---PTLEPSMDIVLKLREAEET 1178
Cdd:pfam05557  152 EQLRQNLEKQQSSLAEAEQRIKELEFEI---------QSQEQDSEIVKNSKSELARIPeleKELERLREHNKHLNENIEN 222

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1179 QNSLQAECDQYRTILAETEGM---LKDLQ----------------------------------KSVEEEERVWKAKVGAA 1221
Cdd:pfam05557  223 KLLLKEEVEDLKRKLEREEKYreeAATLElekekleqelqswvklaqdtglnlrspedlsrriEQLQQREIVLKEENSSL 302

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1222 EEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASaecqnyaKEVAGLRQLLLESQSQLDEAKSE 1301
Cdd:pfam05557  303 TSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLT-------KERDGYRAILESYDKELTMSNYS 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1302 AQKQ------SDELALLKTQLERTEATLEA--EQTRRQKLTAEFEEAQRTACRIQEELEKlraagplESSGKEEITQLKE 1373
Cdd:pfam05557  376 PQLLerieeaEDMTQKMQAHNEEMEAQLSVaeEELGGYKQQAQTLERELQALRQQESLAD-------PSYSKEEVDSLRR 448


                   ...
gi 568918950  1374 RLE 1376
Cdd:pfam05557  449 KLE 451
Gag_spuma pfam03276
Spumavirus gag protein;
408-548 9.67e-04

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 43.58  E-value: 9.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   408 QTKKGEGPQNQGKKGEAAQKQdkkiEGAQNQGKKPEGTSNQgkKGEGAQNQGkkGEGAQNQGK--KGEGAQNQGKKGEGA 485
Cdd:pfam03276  480 QIRASRGPGPGPSAGEGRGGP----ANEGRGGPCNAGGGND--CGANGQNDG--GENIQNGGQelRSQGGQNLRSGGGQG 551

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568918950   486 Q----NQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGegpqNQAKKGEGAQNQGKKGEGAQNQ 548
Cdd:pfam03276  552 QrwgeGRGNRENENTENSEQRPREIQAGSGRPGNAGQGVKG----AAGQGGKGAAGRGGRGNGAGDQ 614
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1231-1416 1.13e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1231 TVKHLEDIVEKLKGELESSDQVrehtshLEAELEKH-MAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDEL 1309
Cdd:COG3206   176 ALEFLEEQLPELRKELEEAEAA------LEEFRQKNgLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1310 ALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTAcRIQEELEKLRAAgplessgKEEITQLKERLEKE-KRLTSDLGRA 1388
Cdd:COG3206   250 GSGPDALPELLQSPVIQQLRAQLAELEAELAELSA-RYTPNHPDVIAL-------RAQIAALRAQLQQEaQRILASLEAE 321

                         170       180
                  ....*....|....*....|....*...
gi 568918950 1389 AIKLQELLKTTQEQLTKEKDTVKKLQEQ 1416
Cdd:COG3206   322 LEALQAREASLQAQLAQLEARLAELPEL 349
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 187-497 1.54e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.28  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  187 SKASSPATSSQGKKGQGAQNQ-AKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEgaQNQGKKGEGAQNQAKKGEGGQ 265
Cdd:NF012221 1540 SSQQADAVSKHAKQDDAAQNAlADKERAEADRQRLEQEKQQQLAAISGSQSQLESTD--QNALETNGQAQRDAILEESRA 1617

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  266 NQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKG--EGAQNQ---AKKGEGAQNQGKKGEGAQNQSKkgegAQNQAKK 340
Cdd:NF012221 1618 VTKELTTLAQGLDALDSQATYAGESGDQWRNPFAGGllDRVQEQlddAKKISGKQLADAKQRHVDNQQK----VKDAVAK 1693

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  341 GEGGQNQAKKGEgaQNQAKKGEGAQNQAKKGEgvQNQAKKGVEgAQNQGKKGEANQNQAKKGegGQNQTKKGEGPQNQGK 420
Cdd:NF012221 1694 SEAGVAQGEQNQ--ANAEQDIDDAKADAEKRK--DDALAKQNE-AQQAESDANAAANDAQSR--GEQDASAAENKANQAQ 1766

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  421 KGEAAQKQDKkiegaqnqGKKPEgtsNQGKKGEGAQNQGKKGEGAQNQG---KKGEGAQNQGKKGEGAQNQGKKG-EGAQ 496
Cdd:NF012221 1767 ADAKGAKQDE--------SDKPN---RQGAAGSGLSGKAYSVEGVAEPGshiNPDSPAAADGRFSEGLTEQEQEAlEGAT 1835


                  .
gi 568918950  497 N 497
Cdd:NF012221 1836 N 1836
PRK09039 PRK09039
peptidoglycan -binding protein;
1235-1331 1.58e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.26  E-value: 1.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1235 LEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAkseaqkqSDELALLKT 1314
Cdd:PRK09039   79 LQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARALAQVELL-------NQQIAALRR 151

                          90
                  ....*....|....*..
gi 568918950 1315 QLERTEATLEAEQTRRQ 1331
Cdd:PRK09039  152 QLAALEAALDASEKRDR 168
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 855-1081 1.84e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 42.81  E-value: 1.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   855 TQLARLQQENSILRDALNQATSQVESKQNT------ELAKLRQELSKVNKELvEKSEASRQEEQQRKALEAKAATFEKQV 928
Cdd:pfam05557  283 RRIEQLQQREIVLKEENSSLTSSARQLEKArreleqELAQYLKKIEDLNKKL-KRHKALVRRLQRRVLLLTKERDGYRAI 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   929 LQL---QASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQE----QQQRVAELHSKLQS-----SEVEVKSKCE 996
Cdd:pfam05557  362 LESydkELTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEelggYKQQAQTLERELQAlrqqeSLADPSYSKE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   997 ELSSLHGQLKEARAENSQLTERIRSIEALLE----------------------AGQAQDTQASHAEANQQQ-TRLKEL-- 1051
Cdd:pfam05557  442 EVDSLRRKLETLELERQRLREQKNELEMELErrclqgdydpkktkvlhlsmnpAAEAYQQRKNQLEKLQAEiERLKRLlk 521

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 568918950  1052 -------------ESQVSCLEKETSELKEAMEQQKGKNNDLRE 1081
Cdd:pfam05557  522 kleddleqvlrlpETTSTMNFKEVLDLRKELESAELKNQRLKE 564
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 883-1406 1.99e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 42.81  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   883 NTELAKLRQELSKVNKELVEKSEASRQEeqqRKALEAKAAT--------------FEKQVLQLQASHKESEEALQKRLEE 948
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKQMELEHKRA---RIELEKKASAlkrqldresdrnqeLQKRIRLLEKREAEAEEALREQAEL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   949 VTRELCRAQTSHANLR---ADAEKAQEQQ----QRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRS 1021
Cdd:pfam05557   78 NRLKKKYLEALNKKLNekeSQLADAREVIsclkNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQN 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1022 IEALLEAGQAQDTQASHAE---------------ANQQQTRLKELESQVSCLEKETSELKEAMEqqkgkNNDLREKNWKA 1086
Cdd:pfam05557  158 LEKQQSSLAEAEQRIKELEfeiqsqeqdseivknSKSELARIPELEKELERLREHNKHLNENIE-----NKLLLKEEVED 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1087 MEALALAERACEEKLRSLTQAKEESEKQLHLAEAqtketlLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSm 1166
Cdd:pfam05557  233 LKRKLEREEKYREEAATLELEKEKLEQELQSWVK------LAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTSS- 305

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1167 divlkLREAEETQNSLQAECDQYRTILAETEGMLKD-------LQKSV---EEEERVWKAKVGAAEEELHKSRVTVKHLE 1236
Cdd:pfam05557  306 -----ARQLEKARRELEQELAQYLKKIEDLNKKLKRhkalvrrLQRRVlllTKERDGYRAILESYDKELTMSNYSPQLLE 380

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1237 diveKLKGELESSDQVREHTSHLEAELEKHMAAASA---ECQNYAKEVAGLR-QLLLESQSQLDEAKSEAQKQSDELALL 1312
Cdd:pfam05557  381 ----RIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGykqQAQTLERELQALRqQESLADPSYSKEEVDSLRRKLETLELE 456

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1313 KTQLERTEATLEAEQTRR-----------------QKLTAEFEEAQrtacriQEELEKLRAagplessgkeEITQLKERL 1375
Cdd:pfam05557  457 RQRLREQKNELEMELERRclqgdydpkktkvlhlsMNPAAEAYQQR------KNQLEKLQA----------EIERLKRLL 520

                          570       580       590
                   ....*....|....*....|....*....|.
gi 568918950  1376 EKEKRLTSDLGRAAIKLQELLKTTQEQLTKE 1406
Cdd:pfam05557  521 KKLEDDLEQVLRLPETTSTMNFKEVLDLRKE 551
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 904-1124 2.15e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 2.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  904 SEASRQEEQQRKALEAKAATFEKQVLQLQAShkesEEALQKRLEEVTRELCRAQtshanlradaEKAQEQQQRVAELHSK 983
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKE----EKALLKQLAALERRIAALA----------RRIRALEQELAALEAE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  984 LQSSEVEVKSKCEELSSLHGQLKEaRAENSQLTERIRSIEALLEAGQAQD-----------TQASHAEANQQQTRLKELE 1052
Cdd:COG4942    85 LAELEKEIAELRAELEAQKEELAE-LLRALYRLGRQPPLALLLSPEDFLDavrrlqylkylAPARREQAEELRADLAELA 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568918950 1053 SQVSCLEKETSELKEAMEQQKGKNNDL---REKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKE 1124
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALealKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
Gag_spuma pfam03276
Spumavirus gag protein;
297-468 2.34e-03

Spumavirus gag protein;


Pssm-ID: 460872 [Multi-domain]  Cd Length: 614  Bit Score: 42.43  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   297 QAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSkkgeGAQNQakKGEGGQNQakKGEGAQNQakkgeGAQNQAKKGEGVQN 376
Cdd:pfam03276  480 QIRASRGPGPGPSAGEGRGGPANEGRGGPCNA----GGGND--CGANGQND--GGENIQNG-----GQELRSQGGQNLRS 546

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   377 QAKKGVEGAQNQGKKGEANQNQAKkgeggqnQTKKGEGPQNqgkkgeaaqkqdkKIEGAQNQGKKPegtsNQGKKGEGAQ 456
Cdd:pfam03276  547 GGGQGQRWGEGRGNRENENTENSE-------QRPREIQAGS-------------GRPGNAGQGVKG----AAGQGGKGAA 602

                          170
                   ....*....|..
gi 568918950   457 NQGKKGEGAQNQ 468
Cdd:pfam03276  603 GRGGRGNGAGDQ 614
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 835-1095 2.73e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.35  E-value: 2.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  835 VQQLQGKIRTLQEQLENGPNTQ--------LARLQQEnsiLRDALNQATSQVES-KQNTELAKLRQELSKVNKELVEKSE 905
Cdd:PRK10929   47 VEALQSALNWLEERKGSLERAKqyqqvidnFPKLSAE---LRQQLNNERDEPRSvPPNMSTDALEQEILQVSSQLLEKSR 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  906 ASRQEeqQRKALEAKAATfeKQVLQLQashkesEEAlQKRLEEVTRELcRAQTShanlradAEKAQEQQQRVAelhskLQ 985
Cdd:PRK10929  124 QAQQE--QDRAREISDSL--SQLPQQQ------TEA-RRQLNEIERRL-QTLGT-------PNTPLAQAQLTA-----LQ 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  986 SSEVEVKSKCEELsslhgQLKEARAENSQLTERIRSieALLEAGQAQ---DTQASHAEANQQQTRLKE--LESqVSCLEK 1060
Cdd:PRK10929  180 AESAALKALVDEL-----ELAQLSANNRQELARLRS--ELAKKRSQQldaYLQALRNQLNSQRQREAEraLES-TELLAE 251

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 568918950 1061 ETSELKEAMEQQKGKNNDL-REKNWKA--MEALALAER 1095
Cdd:PRK10929  252 QSGDLPKSIVAQFKINRELsQALNQQAqrMDLIASQQR 289
mukB PRK04863
chromosome partition protein MukB;
818-1421 2.75e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 2.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  818 AAVQARMQASYRDHVKEVQQLQGKIRTLQEQLENGPNT------QLARLQQENSILRDALNQATSQVESKQNTE-----L 886
Cdd:PRK04863  271 AADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRlvemarELAELNEAESDLEQDYQAASDHLNLVQTALrqqekI 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  887 AKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQ---ASHKESEEALQKR----------LEEVtREL 953
Cdd:PRK04863  351 ERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKsqlADYQQALDVQQTRaiqyqqavqaLERA-KQL 429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  954 CR--------AQTSHANLRAdaeKAQEQQQRVAELHSKLQSSE-----------------------------VEVKSKCE 996
Cdd:PRK04863  430 CGlpdltadnAEDWLEEFQA---KEQEATEELLSLEQKLSVAQaahsqfeqayqlvrkiagevsrseawdvaRELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  997 ELSSLHGQLKEARAENSQLTERIRS----IEALLEAGQAQDTQASHAE-----ANQQQTRLKELESQVSCLEKETSELKE 1067
Cdd:PRK04863  507 EQRHLAEQLQQLRMRLSELEQRLRQqqraERLLAEFCKRLGKNLDDEDeleqlQEELEARLESLSESVSEARERRMALRQ 586

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1068 AMEQQKGKNNDLREKNWKAMEALALAERACE--------------------EKLRSLTQAKEESEKQlhlaeaqtKETLL 1127
Cdd:PRK04863  587 QLEQLQARIQRLAARAPAWLAAQDALARLREqsgeefedsqdvteymqqllERERELTVERDELAAR--------KQALD 658

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1128 ALLPGLSiSAHQNYAEWLQEFKEK-GSELLKK---PPTLE----------PSMD--IVLKLREAEETQNSL--------- 1182
Cdd:PRK04863  659 EEIERLS-QPGGSEDPRLNALAERfGGVLLSEiydDVSLEdapyfsalygPARHaiVVPDLSDAAEQLAGLedcpedlyl 737

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1183 -QAECDQYRTILAETEGMLKDLqkSVEEEERVW------------KAKVGAAEEELHKSRvtvkhlEDIVEKL-KGELES 1248
Cdd:PRK04863  738 iEGDPDSFDDSVFSVEELEKAV--VVKIADRQWrysrfpevplfgRAAREKRIEQLRAER------EELAERYaTLSFDV 809

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1249 SDQVREHtSHLEAELEKHMAAASAEcqNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATL----- 1323
Cdd:PRK04863  810 QKLQRLH-QAFSRFIGSHLAVAFEA--DPEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLprlnl 886

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1324 --------EAEQTRRQklTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQEL 1395
Cdd:PRK04863  887 ladetladRVEEIREQ--LDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEV 964

                         730       740       750
                  ....*....|....*....|....*....|....
gi 568918950 1396 LKT--------TQEQLTKEKDTVKKLQEQLGKAE 1421
Cdd:PRK04863  965 VQRrahfsyedAAEMLAKNSDLNEKLRQRLEQAE 998
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 887-1020 3.14e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  887 AKLRQELSKVNKELVEKSEASRQEEQQRKALEakaatfekqvlqlqashKESEEALQKRLEEVTRELcraqtshANLRAD 966
Cdd:COG0542   400 ARVRMEIDSKPEELDELERRLEQLEIEKEALK-----------------KEQDEASFERLAELRDEL-------AELEEE 455

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568918950  967 AEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIR 1020
Cdd:COG0542   456 LEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLR 509
mukB PRK04863
chromosome partition protein MukB;
885-1323 3.23e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 3.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  885 ELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAkaatfekQVLQLQASHKES----EEALQKRLEEVTRELCRAQtsh 960
Cdd:PRK04863  838 ELRQLNRRRVELERALADHESQEQQQRSQLEQAKE-------GLSALNRLLPRLnllaDETLADRVEEIREQLDEAE--- 907

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  961 anlraDAEKAQEQQQRVAE----LHSKLQSSEvevkskcEELSSLHGQLKEARAENSQLTERIRSIealleagqaqdtqa 1036
Cdd:PRK04863  908 -----EAKRFVQQHGNALAqlepIVSVLQSDP-------EQFEQLKQDYQQAQQTQRDAKQQAFAL-------------- 961

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1037 shAEANQQQTRLKELESQvSCLEKEtSELKEAMEQQkgknndlreknwkameaLALAERACEEKLRSLTQAKEESekqlh 1116
Cdd:PRK04863  962 --TEVVQRRAHFSYEDAA-EMLAKN-SDLNEKLRQR-----------------LEQAEQERTRAREQLRQAQAQL----- 1015

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1117 laeAQTKETLLALlpglsISAHQNYAEWLQEFKEkgsELLKKPPTLEPSMDIVLKLREaEETQNSL---QAECDQYRTIL 1193
Cdd:PRK04863 1016 ---AQYNQVLASL-----KSSYDAKRQMLQELKQ---ELQDLGVPADSGAEERARARR-DELHARLsanRSRRNQLEKQL 1083

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1194 AETEGMLKDLQKSVEEEER--------VWKAKVG-----------AAEEELHKSRVT---VKHLEDIVEKLKGELESSDQ 1251
Cdd:PRK04863 1084 TFCEAEMDNLTKKLRKLERdyhemreqVVNAKAGwcavlrlvkdnGVERRLHRRELAylsADELRSMSDKALGALRLAVA 1163

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568918950 1252 VREHTSHLEAELEKHmAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATL 1323
Cdd:PRK04863 1164 DNEHLRDVLRLSEDP-KRPERKVQFYIAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKL 1234
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 813-1414 3.33e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 3.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   813 REQEIAAVQARMQASYRDHVKEVQQLQGK----IRTLQEQLENGPNTqlarlqqensilRDALNQATSQVESkqntELAK 888
Cdd:pfam01576  325 REQEVTELKKALEEETRSHEAQLQEMRQKhtqaLEELTEQLEQAKRN------------KANLEKAKQALES----ENAE 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   889 LRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQashkESEEALQKRLEEVTRELCRAQTSHANLRADAE 968
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELA----EKLSKLQSELESVSSLLNEAEGKNIKLSKDVS 464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   969 KAQEQQQRVAELHSKLQSSEVEVKSKC----EELSSLHGQLKEARAENSQLTERIRSIEA-LLEAGQAQDTQASHAEANQ 1043
Cdd:pfam01576  465 SLESQLQDTQELLQEETRQKLNLSTRLrqleDERNSLQEQLEEEEEAKRNVERQLSTLQAqLSDMKKKLEEDAGTLEALE 544

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1044 QQTR--LKELESQVSCLEKETSE-----------------LKEAMEQQKGKNNDLREKNWKAMEALAlaeracEEKLRSL 1104
Cdd:pfam01576  545 EGKKrlQRELEALTQQLEEKAAAydklektknrlqqelddLLVDLDHQRQLVSNLEKKQKKFDQMLA------EEKAISA 618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1105 TQAKEESEKQlhlAEAQTKETllallPGLSIS-AHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLK-LREAEETQNSL 1182
Cdd:pfam01576  619 RYAEERDRAE---AEAREKET-----RALSLArALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKnVHELERSKRAL 690

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1183 QAECDQYRTILAETEGMLK-----------DLQKSVEEEERVWKAKVGAAEEelhKSRVTVKHLEDIVEKLKGELESSDQ 1251
Cdd:pfam01576  691 EQQVEEMKTQLEELEDELQatedaklrlevNMQALKAQFERDLQARDEQGEE---KRRQLVKQVRELEAELEDERKQRAQ 767

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1252 VREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQL---LLESQSQLDEAKSeaqkQSDELALLKTQLERTEATLEAEQT 1328
Cdd:pfam01576  768 AVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLqaqMKDLQRELEEARA----SRDEILAQSKESEKKLKNLEAELL 843

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1329 RRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEE--------ITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQ 1400
Cdd:pfam01576  844 QLQEDLAASERARRQAQQERDELADEIASGASGKSALQDekrrlearIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLT 923

                          650
                   ....*....|....
gi 568918950  1401 EQLTKEKDTVKKLQ 1414
Cdd:pfam01576  924 TELAAERSTSQKSE 937
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 876-965 3.54e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.86  E-value: 3.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  876 SQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHkeseEALQKRLEEVTRELcR 955
Cdd:PRK11448  141 ENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQL----EQLQEKAAETSQER-K 215

                          90
                  ....*....|
gi 568918950  956 AQTSHANLRA 965
Cdd:PRK11448  216 QKRKEITDQA 225
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 881-1421 3.90e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.03  E-value: 3.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   881 KQNTELAKLRQELSKVNKELVEK--SEASRQEEQQRKALEAKAATFEKQVLQLqashKESEEALQKRLEEVTRElcraQT 958
Cdd:pfam15921   56 KYEVELDSPRKIIAYPGKEHIERvlEEYSHQVKDLQRRLNESNELHEKQKFYL----RQSVIDLQTKLQEMQME----RD 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   959 SHANLRADAEKAQEqqqrvaELHSKLQSSEVEVKS-KC------EELSSLHGQLKEARAENSQLTERIRSIEALLEAGQA 1031
Cdd:pfam15921  128 AMADIRRRESQSQE------DLRNQLQNTVHELEAaKClkedmlEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1032 QDTqasHAEANQQQTRLKELESQVScleKETSELKEAMEQQKGKNNDLREKnwkaMEALalaeraceeklrsltqaKEES 1111
Cdd:pfam15921  202 KKI---YEHDSMSTMHFRSLGSAIS---KILRELDTEISYLKGRIFPVEDQ----LEAL-----------------KSES 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1112 EKQLHLAEAQTKETLLALlpglsISAHQNYAEWLQEfkeKGSELLKKPPTLEPSMDIVlklREAEETQNSLqaecdqYRT 1191
Cdd:pfam15921  255 QNKIELLLQQHQDRIEQL-----ISEHEVEITGLTE---KASSARSQANSIQSQLEII---QEQARNQNSM------YMR 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1192 ILAETEGMLKDLQKSVEEEERVWKAKVgaaeEELHKSRVTVKhledivEKLKGELESSDQVREHTSHLEAELEKHMAAAS 1271
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKI----EELEKQLVLAN------SELTEARTERDQFSQESGNLDDQLQKLLADLH 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1272 AECQNYAKEVAGLRQL----------LLESQSQLDEAKSEAQKQSDELALLKT----QLERTEATLEAEQTRRQKLTAEF 1337
Cdd:pfam15921  388 KREKELSLEKEQNKRLwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSecqgQMERQMAAIQGKNESLEKVSSLT 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1338 EEAQRTACRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKR--------LTSDLGRAAIKLQEL--LKTTQEQLTKEK 1407
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERaieatnaeITKLRSRVDLKLQELqhLKNEGDHLRNVQ 547

                          570
                   ....*....|....
gi 568918950  1408 DTVKKLQEQLGKAE 1421
Cdd:pfam15921  548 TECEALKLQMAEKD 561
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 880-1417 4.20e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 4.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   880 SKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTR---ELCRA 956
Cdd:TIGR04523  120 NKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKiknKLLKL 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   957 QTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQA 1036
Cdd:TIGR04523  200 ELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1037 ShAEANQQQTRLKELESQVSCLEKE-----TSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAK-EE 1110
Cdd:TIGR04523  280 N-KKIKELEKQLNQLKSEISDLNNQkeqdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSEsEN 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1111 SEKQLHLAEAQTKETLLallpglsISAHQNYAEWLQEFKEKGSELLKKpptlepsmdIVLKLREAEETQNSLQAECDQYR 1190
Cdd:TIGR04523  359 SEKQRELEEKQNEIEKL-------KKENQSYKQEIKNLESQINDLESK---------IQNQEKLNQQKDEQIKKLQQEKE 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1191 TILAETEGMLKDLQKSVEEEERVwKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAA 1270
Cdd:TIGR04523  423 LLEKEIERLKETIIKNNSEIKDL-TNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKL 501

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1271 SAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLtaefeeaqrtacRIQEE 1350
Cdd:TIGR04523  502 NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEID------------EKNKE 569

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568918950  1351 LEKLRAAGPLESSGKEEITQLKERLEKEKrltsdlgRAAIKLQELLKTTQEQLTKEKDTVKKLQEQL 1417
Cdd:TIGR04523  570 IEELKQTQKSLKKKQEEKQELIDQKEKEK-------KDLIKEIEEKEKKISSLEKELEKAKKENEKL 629
Innate_immun pfam12782
Invertebrate innate immunity transcript family; The immune response of the purple sea urchin ...
 224-483 4.42e-03

Invertebrate innate immunity transcript family; The immune response of the purple sea urchin appears to be more complex than previously believed in that it uses immune-related gene families homologous to vertebrate Toll-like and NOD/NALP-like receptor families as well as C-type lectins and a rudimentary complement system. In addition, the species also produces this unusual family of mRNAs, also known as 185/333, which is strongly upregulated in response to pathogen challenge.


Pssm-ID: 432781 [Multi-domain]  Cd Length: 291  Bit Score: 40.91  E-value: 4.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   224 AQNQAKKGEGAQNQAKKGEGAQnqGKKGEGAQNQAKKGEGGQNQAKKGEGA-----QNQGKKGEGAQNQGKKGEGAQNQA 298
Cdd:pfam12782   21 AQRDFNERRGKENDTERGQGGF--GGRPGGMQMGSPRQDGGQMGGRRFDGPesgapQMEGRRQNGGPMGGRRFDGPRFGG 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   299 KKGEGAQNQAKKGEGaqnqGKKGEGAQNQSkkgegAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQA 378
Cdd:pfam12782   99 SRPDGAGGRPFFGQG----GRRGDGEEETD-----AAQQIGDGLGGRGQFDGHGRGHHGHRQGPPQDRPEEQPFGQRNES 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   379 --KKGVEGAQNQGKKGEANQNQAKKGEGGQNQTkkGEGPQNQGKKGEAAQKQDKKIEGAQNQ----GKKPEGTSNQGKKG 452
Cdd:pfam12782  170 sdEDGRPHPRHHGRHHQHHHRNHTEGHQGHNET--GDHPHRHHNKTGDGDQDRPMFEMRPFRfnpfGRKPFGDRPFGRRN 247

                          250       260       270
                   ....*....|....*....|....*....|.
gi 568918950   453 EGAQNQGKKGEGAQNQGKKGEGAQNQGKKGE 483
Cdd:pfam12782  248 GTEEGSPRRDGQRRPYGNRGRWGENESEEKE 278
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 868-1339 6.00e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.25  E-value: 6.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   868 RDALNQATSQVESkQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLE 947
Cdd:pfam05483  267 RDKANQLEEKTKL-QDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKA 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   948 EVTRELCRAQTSHANLRadaEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHG----------QLKEARAENSQLTE 1017
Cdd:pfam05483  346 AHSFVVTEFEATTCSLE---ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKfknnkeveleELKKILAEDEKLLD 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1018 RIRSIEALLEAGQAQDT------QASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNwkamEALA 1091
Cdd:pfam05483  423 EKKQFEKIAEELKGKEQelifllQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHC----DKLL 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1092 LAERACEEKLRSLTQAKEESEKQLHLAEAQTKETL--LALLPGLSISAHQNYAEWLQEFKEKGSEL-LKKPPTLEPSMDI 1168
Cdd:pfam05483  499 LENKELTQEASDMTLELKKHQEDIINCKKQEERMLkqIENLEEKEMNLRDELESVREEFIQKGDEVkCKLDKSEENARSI 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1169 VLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQ--------KSVEEEER--VWKAKVGAAEEELHKSRVTVKHLEDI 1238
Cdd:pfam05483  579 EYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHqenkalkkKGSAENKQlnAYEIKVNKLELELASAKQKFEEIIDN 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1239 V-----------EKLKGELESSDQVREHTSHLEAELEKHMAAASAE-CQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQS 1306
Cdd:pfam05483  659 YqkeiedkkiseEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEmVALMEKHKHQYDKIIEERDSELGLYKNKEQEQS 738

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 568918950  1307 D-------ELALLKTQLERTEATLEAEQTRRQKLTAEFEE 1339
Cdd:pfam05483  739 SakaaleiELSNIKAELLSLKKQLEIEKEEKEKLKMEAKE 778
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 762-990 6.32e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.88  E-value: 6.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   762 RQLEEKEKLLATEQEDAAVAKSKLRELNK---EMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQQL 838
Cdd:pfam17380  354 RQEERKRELERIRQEEIAMEISRMRELERlqmERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   839 QGKIRTLQEQ----LENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSK--VNKELVEKSEASRQEEQ 912
Cdd:pfam17380  434 QREVRRLEEErareMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRkiLEKELEERKQAMIEEER 513

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568918950   913 QRKALEAKAATFEKQVLQLQASHK-ESEEALQKRLEEVTRelcraqtshanlradaekAQEQQQRVAELHSKLQSSEVE 990
Cdd:pfam17380  514 KRKLLEKEMEERQKAIYEEERRREaEEERRKQQEMEERRR------------------IQEQMRKATEERSRLEAMERE 574
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 400-593 7.42e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 40.66  E-value: 7.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  400 KKGEGGQNQTKKGEGPQN-QGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQnQGKKGEgAQNQGKKGEGAQNQ 478
Cdd:NF038329  118 EKGEPGPAGPAGPAGEQGpRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGP-AGKDGE-AGAKGPAGEKGPQG 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  479 GKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGE----GPQNQAKKGEGAQNQGKKGEGAQN--QGKKG 552
Cdd:NF038329  196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDpgptGEDGPQGPDGPAGKDGPRGDRGEAgpDGPDG 275

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 568918950  553 EGAQNQGKKAEGVQSQSKKGEGTQNQGKKG----DGNPnqGKKGE 593
Cdd:NF038329  276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGqngkDGLP--GKDGK 318
Innate_immun pfam12782
Invertebrate innate immunity transcript family; The immune response of the purple sea urchin ...
 204-408 8.56e-03

Invertebrate innate immunity transcript family; The immune response of the purple sea urchin appears to be more complex than previously believed in that it uses immune-related gene families homologous to vertebrate Toll-like and NOD/NALP-like receptor families as well as C-type lectins and a rudimentary complement system. In addition, the species also produces this unusual family of mRNAs, also known as 185/333, which is strongly upregulated in response to pathogen challenge.


Pssm-ID: 432781 [Multi-domain]  Cd Length: 291  Bit Score: 39.75  E-value: 8.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   204 AQNQAKKGEGAQNQGKKGEGAQnqAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGgqnqaKKGEGAQNQGKKGEG 283
Cdd:pfam12782   21 AQRDFNERRGKENDTERGQGGF--GGRPGGMQMGSPRQDGGQMGGRRFDGPESGAPQMEG-----RRQNGGPMGGRRFDG 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   284 AQNQGKKGEGAQNQAKKGEGA-QNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGE 362
Cdd:pfam12782   94 PRFGGSRPDGAGGRPFFGQGGrRGDGEEETDAAQQIGDGLGGRGQFDGHGRGHHGHRQGPPQDRPEEQPFGQRNESSDED 173

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 568918950   363 GAQNQAKKGEGVQNQAKKGVEGAQNQGKKGE-ANQNQAKKGEGGQNQ 408
Cdd:pfam12782  174 GRPHPRHHGRHHQHHHRNHTEGHQGHNETGDhPHRHHNKTGDGDQDR 220
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1261-1422 8.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.13  E-value: 8.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1261 AELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEA 1340
Cdd:COG4942    30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1341 QRTACR---------------IQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQ--- 1402
Cdd:COG4942   110 LRALYRlgrqpplalllspedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEEraa 189

                         170       180
                  ....*....|....*....|
gi 568918950 1403 LTKEKDTVKKLQEQLGKAED 1422
Cdd:COG4942   190 LEALKAERQKLLARLEKELA 209
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
757-955 8.92e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 8.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  757 VAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEM--ASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKE 834
Cdd:COG4913   687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELeqAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  835 V-QQLQGKIRTLQEQLENGpNTQLARLQQE-NSILRDALNQATSQVESkqNTELAKLRQELskvnkelveksEASRQEEQ 912
Cdd:COG4913   767 LrENLEERIDALRARLNRA-EEELERAMRAfNREWPAETADLDADLES--LPEYLALLDRL-----------EEDGLPEY 832

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 568918950  913 QRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCR 955
Cdd:COG4913   833 EERFKELLNENSIEFVADLLSKLRRAIREIKERIDPLNDSLKR 875
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 854-1325 9.32e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.39  E-value: 9.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   854 NTQLARLQQENSILRDALNQATSQVESKQN------TELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQ 927
Cdd:TIGR04523  217 ESQISELKKQNNQLKDNIEKKQQEINEKTTeisntqTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950   928 VLQLQashKESEEALQKRL-EEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLK 1006
Cdd:TIGR04523  297 ISDLN---NQKEQDWNKELkSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1007 EARAENSQLTERIRSIEALLEAGQaQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWka 1086
Cdd:TIGR04523  374 KLKKENQSYKQEIKNLESQINDLE-SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDS-- 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1087 mealalaerACEEKLRSLTQAKEESEKQLHLAEAQTKetllallpglsiSAHQNYAEWLQEFKEKGSELLKkppTLEPSM 1166
Cdd:TIGR04523  451 ---------VKELIIKNLDNTRESLETQLKVLSRSIN------------KIKQNLEQKQKELKSKEKELKK---LNEEKK 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1167 DIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEervwkakvgaaeeelhKSRVTVKHLEDIVEKLKGEL 1246
Cdd:TIGR04523  507 ELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD----------------DFELKKENLEKEIDEKNKEI 570

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568918950  1247 ESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALLKTQLERTEATLEA 1325
Cdd:TIGR04523  571 EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649
PRK11637 PRK11637
AmiB activator; Provisional
 890-1125 9.64e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 40.06  E-value: 9.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  890 RQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESeealQKRLEEVTRELCRAQTSHANLradaEK 969
Cdd:PRK11637   46 RDQLKSIQQDIAAKEKSVRQQQQQRASLLAQLKKQEEAISQASRKLRET----QNTLNQLNKQIDELNASIAKL----EQ 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  970 AQEQQQRV--AEL--------HSKLQ---SSEVEVKSkcEELSSLHGQLKEARAEN----SQLTERIRSIEALLEAGQAQ 1032
Cdd:PRK11637  118 QQAAQERLlaAQLdaafrqgeHTGLQlilSGEESQRG--ERILAYFGYLNQARQETiaelKQTREELAAQKAELEEKQSQ 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950 1033 DTQASHAEANQQQTrlkeLESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERacEEKLRSLTQAKEESE 1112
Cdd:PRK11637  196 QKTLLYEQQAQQQK----LEQARNERKKTLTGLESSLQKDQQQLSELRANESRLRDSIARAER--EAKARAEREAREAAR 269

                         250
                  ....*....|...
gi 568918950 1113 KQLHLAEAQTKET 1125
Cdd:PRK11637  270 VRDKQKQAKRKGS 282
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1056-1346 9.81e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 40.40  E-value: 9.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1056 SCLEKETSELKEAME-----QQKGKNNDLREKNWKAMEALALAERAcEEKLRSLTQAKEESEKQLhLAEAQTKETLLALL 1130
Cdd:pfam05667  207 SLLERNAAELAAAQEweeewNSQGLASRLTPEEYRKRKRTKLLKRI-AEQLRSAALAGTEATSGA-SRSAQDLAELLSSF 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1131 PGLSISAHQ-------NYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKlREAEetQNSLQAECDQYRTILAETEGMLKDL 1203
Cdd:pfam05667  285 SGSSTTDTGltkgsrfTHTEKLQFTNEAPAATSSPPTKVETEEELQQQ-REEE--LEELQEQLEDLESSIQELEKEIKKL 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918950  1204 QKS---VEEEERVWKAKVGAAEEELHKSRVTVKHLEDI---VEKLKGELESSDQVREHtshLEAELEKHMAAASAEcqny 1277
Cdd:pfam05667  362 ESSikqVEEELEELKEQNEELEKQYKVKKKTLDLLPDAeenIAKLQALVDASAQRLVE---LAGQWEKHRVPLIEE---- 434

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568918950  1278 akevagLRQLllesQSQLDEAKSEAQKQSDELALLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACR 1346
Cdd:pfam05667  435 ------YRAL----KEAKSNKEDESQRKLEEIKELREKIKEVAEEAKQKEELYKQLVAEYERLPKDVSR 493
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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