|
Name |
Accession |
Description |
Interval |
E-value |
| NifS |
COG1104 |
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino ... |
66-474 |
2.20e-154 |
|
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino acid transport and metabolism];
Pssm-ID: 440721 [Multi-domain] Cd Length: 381 Bit Score: 443.72 E-value: 2.20e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMV 145
Cdd:COG1104 4 IYLDNAATTPVDPEVLEAMLPYLTEYFGNPSSLHSFGREARAALEEAREQVAALLGADPEEIIFTSGGTEANNLAIKGAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 146 RCFHEqqtlKGNmvdqhspeegtrpHFITCTVEHDSIRLPLEHLvENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTCLV 225
Cdd:COG1104 84 RAYRK----KGK-------------HIITSAIEHPAVLETARFL-EKEGFEVTYLPVDE-DGRVDLEALEAALRPDTALV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 226 TIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYV 304
Cdd:COG1104 145 SVMHANNETGTIQPIAEIAEIAKEHG----------VLFHTDAVQAVGKIPVDVKELGVDLLSLSAHKIYGPKgVGALYV 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 305 RgvgKLTPLYPMLFGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKrIHLNSrfPG 384
Cdd:COG1104 215 R---KGVRLEPLIHGGGQERGLRSGTENVPGIVGLGKAAELAAEELEEEAARLRALRDRLEEGLLAAIPG-VVING--DP 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 385 VERLPNTCNFSIQGsqLQGYTVLAQC--RTLLASVGASCHSNHeDRPSPVLLSCGIPVDVARNAVRLSVGRGTTRADVDL 462
Cdd:COG1104 289 ENRLPNTLNFSFPG--VEGEALLLALdlAGIAVSSGSACSSGS-LEPSHVLLAMGLDEELAHGSIRFSLGRFTTEEEIDR 365
|
410
....*....|..
gi 568909391 463 IVQDLKQAVAQL 474
Cdd:COG1104 366 AIEALKEIVARL 377
|
|
| PLN02651 |
PLN02651 |
cysteine desulfurase |
66-461 |
5.39e-122 |
|
cysteine desulfurase
Pssm-ID: 178257 [Multi-domain] Cd Length: 364 Bit Score: 360.51 E-value: 5.39e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPSS-SYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSM 144
Cdd:PLN02651 1 LYLDMQATTPIDPRVLDAMLPFLIEHFGNPHSrTHLYGWESEDAVEKARAQVAALIGADPKEIIFTSGATESNNLAIKGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 145 VRCFHEQqtlkgnmvdqhspeegtRPHFITCTVEHDSIRLPLEHLVENQMaEVTFVPVSKvNGQAEVEDILAAVRPTTCL 224
Cdd:PLN02651 81 MHFYKDK-----------------KKHVITTQTEHKCVLDSCRHLQQEGF-EVTYLPVKS-DGLVDLDELAAAIRPDTAL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 225 VTIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALY 303
Cdd:PLN02651 142 VSVMAVNNEIGVIQPVEEIGELCREKK----------VLFHTDAAQAVGKIPVDVDDLGVDLMSISGHKIYGPKgVGALY 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 304 VRGvGKLTPLYPMLFGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKrIHLNSRFP 383
Cdd:PLN02651 212 VRR-RPRVRLEPLMSGGGQERGRRSGTENTPLVVGLGAACELAMKEMDYDEKHMKALRERLLNGLRAKLGG-VRVNGPRD 289
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568909391 384 GVERLPNTCNFSIQGsqLQGYTVLAQCRTLLASVGASCHSNhEDRPSPVLLSCGIPVDVARNAVRLSVGRGTTRADVD 461
Cdd:PLN02651 290 PEKRYPGTLNLSFAY--VEGESLLMGLKEVAVSSGSACTSA-SLEPSYVLRALGVPEEMAHGSLRLGVGRFTTEEEVD 364
|
|
| FeS_nifS |
TIGR03402 |
cysteine desulfurase NifS; Members of this protein family are NifS, one of several related ... |
66-474 |
1.72e-111 |
|
cysteine desulfurase NifS; Members of this protein family are NifS, one of several related families of cysteine desulfurase involved in iron-sulfur (FeS) cluster biosynthesis. NifS is part of the NIF system, usually associated with other nif genes involved in nitrogenase expression and nitrogen fixation. The protein family is given a fairly broad interpretation here. It includes a clade nearly always found in extended nitrogen fixation genomic regions, plus a second clade more closely related to the first than to IscS and also part of NifS-like/NifU-like systems. This model does not extend to a more distantly clade found in the epsilon proteobacteria such as Helicobacter pylori, also named NifS in the literature, built instead in TIGR03403.
Pssm-ID: 132443 [Multi-domain] Cd Length: 379 Bit Score: 334.20 E-value: 1.72e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMV 145
Cdd:TIGR03402 1 IYLDNNATTRVDPEVLEAMLPYFTEYFGNPSSMHSFGGEVGKAVEEAREQVAKLLGAEPDEIIFTSGGTESDNTAIKSAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 146 RCFHEqqtlkgnmvdqhspeegtRPHFITCTVEHDSIRLPLEHLvENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTCLV 225
Cdd:TIGR03402 81 AAQPE------------------KRHIITTAVEHPAVLSLCQHL-EKQGYKVTYLPVDE-EGRLDLEELRAAITDDTALV 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 226 TIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYV 304
Cdd:TIGR03402 141 SVMWANNETGTIFPIEEIGEIAKERG----------ALFHTDAVQAVGKIPIDLKEMNIDMLSLSGHKLHGPKgVGALYI 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 305 RgvgKLTPLYPMLFGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKrIHLNSrfPG 384
Cdd:TIGR03402 211 R---KGTRFRPLLRGGHQERGRRAGTENVPGIVGLGKAAELATEHLEEENTRVRALRDRLEAGLLARIPD-ARLNG--DP 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 385 VERLPNTCNFSIQGsqLQGYTVLaqcrTLL------ASVGASCHSNHEDrPSPVLLSCGIPVDVARNAVRLSVGRGTTRA 458
Cdd:TIGR03402 285 TKRLPNTVNISFEY--IEGEAIL----LLLdmegicASSGSACTSGSLE-PSHVLRAMGVPHTAAHGSIRFSLSRYNTEE 357
|
410
....*....|....*.
gi 568909391 459 DVDLIVQDLKQAVAQL 474
Cdd:TIGR03402 358 DIDYVLEVLPPIIARL 373
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
66-462 |
1.85e-73 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 235.99 E-value: 1.85e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNP-SSSYVSGRKAKDIINAARASLAKMIGGK-PQDIIFTSGGTESNNLVIHS 143
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVhRGVHTLGKEATQAYEEAREKVAEFINAPsNDEIIFTSGTTEAINLVALS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 144 MVRcfheqqtlkgnmvdqhSPEEGTrpHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTC 223
Cdd:pfam00266 81 LGR----------------SLKPGD--EIVITEMEHHANLVPWQELAKRTGARVRVLPLDE-DGLLDLDELEKLITPKTK 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 224 LVTIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGAL 302
Cdd:pfam00266 142 LVAITHVSNVTGTIQPVPEIGKLAHQYG----------ALVLVDAAQAIGHRPIDVQKLGVDFLAFSGHKLYGPTgIGVL 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 303 YVRGvGKLTPLYPMLFGGG--------------QEWNFRPGTENTPMIAGLGKAADLVSE-NCETYEAHMRDIRDYLEER 367
Cdd:pfam00266 212 YGRR-DLLEKMPPLLGGGGmietvslqestfadAPWKFEAGTPNIAGIIGLGAALEYLSEiGLEAIEKHEHELAQYLYER 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 368 LEAEFGKRIHlnsrfpGVERLPNTCNFSIQGsqLQGYTVLaqcrTLLASVGASCHSNHedrpspvllSCGIPVDVARN-- 445
Cdd:pfam00266 291 LLSLPGIRLY------GPERRASIISFNFKG--VHPHDVA----TLLDESGIAVRSGH---------HCAQPLMVRLGlg 349
|
410
....*....|....*...
gi 568909391 446 -AVRLSVGRGTTRADVDL 462
Cdd:pfam00266 350 gTVRASFYIYNTQEDVDR 367
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
66-467 |
3.40e-50 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 175.35 E-value: 3.40e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPS-SSYVSGRKAKDIINAARASLAKMIGGK-PQDIIFTSGGTESNNLVIHS 143
Cdd:cd06453 1 VYLDNAATSQKPQPVIDAIVDYYRHYNANVHrGVHELSARATDAYEAAREKVARFINAPsPDEIIFTRNTTEAINLVAYG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 144 MVRCFHEqqtlkGNmvdqhspeegtrpHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTC 223
Cdd:cd06453 81 LGRANKP-----GD-------------EIVTSVMEHHSNIVPWQQLAERTGAKLKVVPVDD-DGQLDLEALEKLLTERTK 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 224 LVTIMLANNETGVIMPVSEISRRIKAlnqiraaSGLPrVLVhtDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGAL 302
Cdd:cd06453 142 LVAVTHVSNVLGTINPVKEIGEIAHE-------AGVP-VLV--DGAQSAGHMPVDVQDLGCDFLAFSGHKMLGPTgIGVL 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 303 YVRGvGKLTPLYPMLFGG---------GQEWN-----FRPGTENTPMIAGLGKAADLV-SENCETYEAHMRDIRDYLEER 367
Cdd:cd06453 212 YGKE-ELLEEMPPYGGGGemieevsfeETTYAdlphkFEAGTPNIAGAIGLGAAIDYLeKIGMEAIAAHEHELTAYALER 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 368 LEAefgkrihlnsrFPGVERLPNTCN------FSIQGsqLQGYTVlaqcRTLLASVGASCHSNHEdrpspvllsCGIPVD 441
Cdd:cd06453 291 LSE-----------IPGVRVYGDAEDragvvsFNLEG--IHPHDV----ATILDQYGIAVRAGHH---------CAQPLM 344
|
410 420
....*....|....*....|....*....
gi 568909391 442 VARN---AVRLSVGRGTTRADVDLIVQDL 467
Cdd:cd06453 345 RRLGvpgTVRASFGLYNTEEEIDALVEAL 373
|
|
| f2_encap_cargo1 |
NF041166 |
family 2A encapsulin nanocompartment cargo protein cysteine desulfurase; Capsid-like ... |
111-354 |
7.55e-09 |
|
family 2A encapsulin nanocompartment cargo protein cysteine desulfurase; Capsid-like encapsulin nanocompartments are commonly found in bacteria and archaea. Encapsulin nanocompartments, which are assembled from shell proteins, encapsulate various cargo proteins, typically peroxidases or ferritin-like proteins, to protect cells from oxidative stress caused by peroxide. Proteins of this family are cysteine desulfurases with an additional N-terminal encapsulation targeting sequence (~200 aa) that is necessary and sufficient for compartmentalization.
Pssm-ID: 469077 [Multi-domain] Cd Length: 623 Bit Score: 57.94 E-value: 7.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 111 AARASLAKMIG-GKPQDIIFTSGGTESNNLVIHSMVRcfheqQTLKgnmvdqhspeEGtrphfitctvehDSIRLP-LEH 188
Cdd:NF041166 293 GAREKVRRFIGaPSVDEIIFVRGTTEAINLVAKSWGR-----QNIG----------AG------------DEIIVShLEH 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 189 ---LVE-NQMAEVT-----FVPVSKvNGQ---AEVEDILAavrPTTCLVTIMLANNETGVIMPVSEI---SRRIKAlnqi 253
Cdd:NF041166 346 hanIVPwQQLAQETgaklrVIPVDD-SGQillDEYAKLLN---PRTKLVSVTQVSNALGTVTPVKEIialAHRAGA---- 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 254 raasglpRVLVhtDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYvrgvGKL-----TPLYPmlfGGGqewN-- 325
Cdd:NF041166 418 -------KVLV--DGAQSVSHMPVDVQALDADFFVFSGHKVFGPTgIGVVY----GKRdlleaMPPWQ---GGG---Nmi 478
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 568909391 326 ----------------FRPGTENtpmIA---GLGKAADLVS----ENCETYE 354
Cdd:NF041166 479 advtfektvyqpapnrFEAGTGN---IAdavGLGAALDYVErigiENIARYE 527
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NifS |
COG1104 |
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino ... |
66-474 |
2.20e-154 |
|
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino acid transport and metabolism];
Pssm-ID: 440721 [Multi-domain] Cd Length: 381 Bit Score: 443.72 E-value: 2.20e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMV 145
Cdd:COG1104 4 IYLDNAATTPVDPEVLEAMLPYLTEYFGNPSSLHSFGREARAALEEAREQVAALLGADPEEIIFTSGGTEANNLAIKGAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 146 RCFHEqqtlKGNmvdqhspeegtrpHFITCTVEHDSIRLPLEHLvENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTCLV 225
Cdd:COG1104 84 RAYRK----KGK-------------HIITSAIEHPAVLETARFL-EKEGFEVTYLPVDE-DGRVDLEALEAALRPDTALV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 226 TIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYV 304
Cdd:COG1104 145 SVMHANNETGTIQPIAEIAEIAKEHG----------VLFHTDAVQAVGKIPVDVKELGVDLLSLSAHKIYGPKgVGALYV 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 305 RgvgKLTPLYPMLFGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKrIHLNSrfPG 384
Cdd:COG1104 215 R---KGVRLEPLIHGGGQERGLRSGTENVPGIVGLGKAAELAAEELEEEAARLRALRDRLEEGLLAAIPG-VVING--DP 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 385 VERLPNTCNFSIQGsqLQGYTVLAQC--RTLLASVGASCHSNHeDRPSPVLLSCGIPVDVARNAVRLSVGRGTTRADVDL 462
Cdd:COG1104 289 ENRLPNTLNFSFPG--VEGEALLLALdlAGIAVSSGSACSSGS-LEPSHVLLAMGLDEELAHGSIRFSLGRFTTEEEIDR 365
|
410
....*....|..
gi 568909391 463 IVQDLKQAVAQL 474
Cdd:COG1104 366 AIEALKEIVARL 377
|
|
| PLN02651 |
PLN02651 |
cysteine desulfurase |
66-461 |
5.39e-122 |
|
cysteine desulfurase
Pssm-ID: 178257 [Multi-domain] Cd Length: 364 Bit Score: 360.51 E-value: 5.39e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPSS-SYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSM 144
Cdd:PLN02651 1 LYLDMQATTPIDPRVLDAMLPFLIEHFGNPHSrTHLYGWESEDAVEKARAQVAALIGADPKEIIFTSGATESNNLAIKGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 145 VRCFHEQqtlkgnmvdqhspeegtRPHFITCTVEHDSIRLPLEHLVENQMaEVTFVPVSKvNGQAEVEDILAAVRPTTCL 224
Cdd:PLN02651 81 MHFYKDK-----------------KKHVITTQTEHKCVLDSCRHLQQEGF-EVTYLPVKS-DGLVDLDELAAAIRPDTAL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 225 VTIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALY 303
Cdd:PLN02651 142 VSVMAVNNEIGVIQPVEEIGELCREKK----------VLFHTDAAQAVGKIPVDVDDLGVDLMSISGHKIYGPKgVGALY 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 304 VRGvGKLTPLYPMLFGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKrIHLNSRFP 383
Cdd:PLN02651 212 VRR-RPRVRLEPLMSGGGQERGRRSGTENTPLVVGLGAACELAMKEMDYDEKHMKALRERLLNGLRAKLGG-VRVNGPRD 289
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568909391 384 GVERLPNTCNFSIQGsqLQGYTVLAQCRTLLASVGASCHSNhEDRPSPVLLSCGIPVDVARNAVRLSVGRGTTRADVD 461
Cdd:PLN02651 290 PEKRYPGTLNLSFAY--VEGESLLMGLKEVAVSSGSACTSA-SLEPSYVLRALGVPEEMAHGSLRLGVGRFTTEEEVD 364
|
|
| FeS_nifS |
TIGR03402 |
cysteine desulfurase NifS; Members of this protein family are NifS, one of several related ... |
66-474 |
1.72e-111 |
|
cysteine desulfurase NifS; Members of this protein family are NifS, one of several related families of cysteine desulfurase involved in iron-sulfur (FeS) cluster biosynthesis. NifS is part of the NIF system, usually associated with other nif genes involved in nitrogenase expression and nitrogen fixation. The protein family is given a fairly broad interpretation here. It includes a clade nearly always found in extended nitrogen fixation genomic regions, plus a second clade more closely related to the first than to IscS and also part of NifS-like/NifU-like systems. This model does not extend to a more distantly clade found in the epsilon proteobacteria such as Helicobacter pylori, also named NifS in the literature, built instead in TIGR03403.
Pssm-ID: 132443 [Multi-domain] Cd Length: 379 Bit Score: 334.20 E-value: 1.72e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMV 145
Cdd:TIGR03402 1 IYLDNNATTRVDPEVLEAMLPYFTEYFGNPSSMHSFGGEVGKAVEEAREQVAKLLGAEPDEIIFTSGGTESDNTAIKSAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 146 RCFHEqqtlkgnmvdqhspeegtRPHFITCTVEHDSIRLPLEHLvENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTCLV 225
Cdd:TIGR03402 81 AAQPE------------------KRHIITTAVEHPAVLSLCQHL-EKQGYKVTYLPVDE-EGRLDLEELRAAITDDTALV 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 226 TIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYV 304
Cdd:TIGR03402 141 SVMWANNETGTIFPIEEIGEIAKERG----------ALFHTDAVQAVGKIPIDLKEMNIDMLSLSGHKLHGPKgVGALYI 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 305 RgvgKLTPLYPMLFGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKrIHLNSrfPG 384
Cdd:TIGR03402 211 R---KGTRFRPLLRGGHQERGRRAGTENVPGIVGLGKAAELATEHLEEENTRVRALRDRLEAGLLARIPD-ARLNG--DP 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 385 VERLPNTCNFSIQGsqLQGYTVLaqcrTLL------ASVGASCHSNHEDrPSPVLLSCGIPVDVARNAVRLSVGRGTTRA 458
Cdd:TIGR03402 285 TKRLPNTVNISFEY--IEGEAIL----LLLdmegicASSGSACTSGSLE-PSHVLRAMGVPHTAAHGSIRFSLSRYNTEE 357
|
410
....*....|....*.
gi 568909391 459 DVDLIVQDLKQAVAQL 474
Cdd:TIGR03402 358 DIDYVLEVLPPIIARL 373
|
|
| PRK02948 |
PRK02948 |
IscS subfamily cysteine desulfurase; |
66-476 |
2.70e-82 |
|
IscS subfamily cysteine desulfurase;
Pssm-ID: 179511 [Multi-domain] Cd Length: 381 Bit Score: 259.28 E-value: 2.70e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMv 145
Cdd:PRK02948 2 IYLDYAATTPMSKEALQTYQKAASQYFGNESSLHDIGGTASSLLQVCRKTFAEMIGGEEQGIYFTSGGTESNYLAIQSL- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 146 rcfheqqtLKGNmvdqhsPEEGTrpHFITCTVEHDSIRLPLEHLvENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTCLV 225
Cdd:PRK02948 81 --------LNAL------PQNKK--HIITTPMEHASIHSYFQSL-ESQGYTVTEIPVDK-SGLIRLVDLERAITPDTVLA 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 226 TIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYV 304
Cdd:PRK02948 143 SIQHANSEIGTIQPIAEIGALLKKYN----------VLFHSDCVQTFGKLPIDVFEMGIDSLSVSAHKIYGPKgVGAVYI 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 305 RGVGKLTPLYPmlfGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAefgKRIHLNSRFPG 384
Cdd:PRK02948 213 NPQVRWKPVFP---GTTHEKGFRPGTVNVPGIAAFLTAAENILKNMQEESLRFKELRSYFLEQIQT---LPLPIEVEGHS 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 385 VERLPNTCNFSIQGSQLQgYTVLAQCRTLLA-SVGASCHSNHEDrPSPVLLSCGIPVDVARNAVRLSVGRGTTRADVDLI 463
Cdd:PRK02948 287 TSCLPHIIGVTIKGIEGQ-YTMLECNRRGIAiSTGSACQVGKQE-PSKTMLAIGKTYEEAKQFVRFSFGQQTTKDQIDTT 364
|
410
....*....|...
gi 568909391 464 VQDLKQAVAQLEG 476
Cdd:PRK02948 365 IHALETIGNQFYR 377
|
|
| PRK14012 |
PRK14012 |
IscS subfamily cysteine desulfurase; |
66-474 |
1.33e-80 |
|
IscS subfamily cysteine desulfurase;
Pssm-ID: 184450 [Multi-domain] Cd Length: 404 Bit Score: 255.64 E-value: 1.33e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTE--AMKEAWGNPSS-SYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIH 142
Cdd:PRK14012 5 IYLDYSATTPVDPRVAEKMMPylTMDGTFGNPASrSHRFGWQAEEAVDIARNQIADLIGADPREIVFTSGATESDNLAIK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 143 SMVRCFHEqqtlKGNmvdqhspeegtrpHFITCTVEHDSIRLPLEHLvENQMAEVTFVPVsKVNGQAEVEDILAAVRPTT 222
Cdd:PRK14012 85 GAAHFYQK----KGK-------------HIITSKTEHKAVLDTCRQL-EREGFEVTYLDP-QSNGIIDLEKLEAAMRDDT 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 223 CLVTIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGA 301
Cdd:PRK14012 146 ILVSIMHVNNEIGVIQDIAAIGEICRERG----------IIFHVDAAQSVGKVPIDLSKLKVDLMSFSAHKIYGPKgIGA 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 302 LYVRGVGKLTpLYPMLFGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEfgKRIHLNSR 381
Cdd:PRK14012 216 LYVRRKPRVR-LEAQMHGGGHERGMRSGTLPTHQIVGMGEAARIAKEEMATENERIRALRDRLWNGIKDI--EEVYLNGD 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 382 FPgvERLPNTCNFSIQGsqLQGYTVLAQCRTLLASVGASCHSNHEDrPSPVLLSCGIPVDVARNAVRLSVGRGTTRADVD 461
Cdd:PRK14012 293 LE--QRVPGNLNVSFNY--VEGESLIMALKDLAVSSGSACTSASLE-PSYVLRALGLNDELAHSSIRFSLGRFTTEEEID 367
|
410
....*....|...
gi 568909391 462 LIVQDLKQAVAQL 474
Cdd:PRK14012 368 YAIELVRKSIGKL 380
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
66-462 |
1.85e-73 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 235.99 E-value: 1.85e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNP-SSSYVSGRKAKDIINAARASLAKMIGGK-PQDIIFTSGGTESNNLVIHS 143
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVhRGVHTLGKEATQAYEEAREKVAEFINAPsNDEIIFTSGTTEAINLVALS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 144 MVRcfheqqtlkgnmvdqhSPEEGTrpHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTC 223
Cdd:pfam00266 81 LGR----------------SLKPGD--EIVITEMEHHANLVPWQELAKRTGARVRVLPLDE-DGLLDLDELEKLITPKTK 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 224 LVTIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGAL 302
Cdd:pfam00266 142 LVAITHVSNVTGTIQPVPEIGKLAHQYG----------ALVLVDAAQAIGHRPIDVQKLGVDFLAFSGHKLYGPTgIGVL 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 303 YVRGvGKLTPLYPMLFGGG--------------QEWNFRPGTENTPMIAGLGKAADLVSE-NCETYEAHMRDIRDYLEER 367
Cdd:pfam00266 212 YGRR-DLLEKMPPLLGGGGmietvslqestfadAPWKFEAGTPNIAGIIGLGAALEYLSEiGLEAIEKHEHELAQYLYER 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 368 LEAEFGKRIHlnsrfpGVERLPNTCNFSIQGsqLQGYTVLaqcrTLLASVGASCHSNHedrpspvllSCGIPVDVARN-- 445
Cdd:pfam00266 291 LLSLPGIRLY------GPERRASIISFNFKG--VHPHDVA----TLLDESGIAVRSGH---------HCAQPLMVRLGlg 349
|
410
....*....|....*...
gi 568909391 446 -AVRLSVGRGTTRADVDL 462
Cdd:pfam00266 350 gTVRASFYIYNTQEDVDR 367
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
62-472 |
1.57e-54 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 187.27 E-value: 1.57e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 62 GPQKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPS-SSYVSGRKAKDIINAARASLAKMIGGK-PQDIIFTSGGTESNNL 139
Cdd:COG0520 13 GKPLVYLDNAATGQKPRPVIDAIRDYYEPYNANVHrGAHELSAEATDAYEAAREKVARFIGAAsPDEIIFTRGTTEAINL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 140 VIHSMVRcfheqqtLKgnmvdqhspeEGTrpHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKvNGQAEVEDILAAVR 219
Cdd:COG0520 93 VAYGLGR-------LK----------PGD--EILITEMEHHSNIVPWQELAERTGAEVRVIPLDE-DGELDLEALEALLT 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 220 PTTCLVTIMLANNETGVIMPVSEISRRIKALNqiraasglprVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR- 298
Cdd:COG0520 153 PRTKLVAVTHVSNVTGTVNPVKEIAALAHAHG----------ALVLVDGAQSVPHLPVDVQALGCDFYAFSGHKLYGPTg 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 299 IGALYVRGvGKLTPLYPMLFGGG-------QEWNFRP-------GTENTPMIAGLGKAADLVSE-NCETYEAHMRDIRDY 363
Cdd:COG0520 223 IGVLYGKR-ELLEALPPFLGGGGmiewvsfDGTTYADlprrfeaGTPNIAGAIGLGAAIDYLEAiGMEAIEARERELTAY 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 364 LEERLEAEFGkrIHLNSRFPGVERLPnTCNFSIQGsqLQGYTVlaqcRTLLASVG----ASCHSNHedrpsPVLLSCGIP 439
Cdd:COG0520 302 ALEGLAAIPG--VRILGPADPEDRSG-IVSFNVDG--VHPHDV----AALLDDEGiavrAGHHCAQ-----PLMRRLGVP 367
|
410 420 430
....*....|....*....|....*....|...
gi 568909391 440 vdvarNAVRLSVGRGTTRADVDLIVQDLKQAVA 472
Cdd:COG0520 368 -----GTVRASFHLYNTEEEIDRLVEALKKLAE 395
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
66-467 |
3.40e-50 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 175.35 E-value: 3.40e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDYNATTPLEPEVIQAVTEAMKEAWGNPS-SSYVSGRKAKDIINAARASLAKMIGGK-PQDIIFTSGGTESNNLVIHS 143
Cdd:cd06453 1 VYLDNAATSQKPQPVIDAIVDYYRHYNANVHrGVHELSARATDAYEAAREKVARFINAPsPDEIIFTRNTTEAINLVAYG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 144 MVRCFHEqqtlkGNmvdqhspeegtrpHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKvNGQAEVEDILAAVRPTTC 223
Cdd:cd06453 81 LGRANKP-----GD-------------EIVTSVMEHHSNIVPWQQLAERTGAKLKVVPVDD-DGQLDLEALEKLLTERTK 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 224 LVTIMLANNETGVIMPVSEISRRIKAlnqiraaSGLPrVLVhtDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGAL 302
Cdd:cd06453 142 LVAVTHVSNVLGTINPVKEIGEIAHE-------AGVP-VLV--DGAQSAGHMPVDVQDLGCDFLAFSGHKMLGPTgIGVL 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 303 YVRGvGKLTPLYPMLFGG---------GQEWN-----FRPGTENTPMIAGLGKAADLV-SENCETYEAHMRDIRDYLEER 367
Cdd:cd06453 212 YGKE-ELLEEMPPYGGGGemieevsfeETTYAdlphkFEAGTPNIAGAIGLGAAIDYLeKIGMEAIAAHEHELTAYALER 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 368 LEAefgkrihlnsrFPGVERLPNTCN------FSIQGsqLQGYTVlaqcRTLLASVGASCHSNHEdrpspvllsCGIPVD 441
Cdd:cd06453 291 LSE-----------IPGVRVYGDAEDragvvsFNLEG--IHPHDV----ATILDQYGIAVRAGHH---------CAQPLM 344
|
410 420
....*....|....*....|....*....
gi 568909391 442 VARN---AVRLSVGRGTTRADVDLIVQDL 467
Cdd:cd06453 345 RRLGvpgTVRASFGLYNTEEEIDALVEAL 373
|
|
| sufS |
TIGR01979 |
cysteine desulfurases, SufSfamily; This model represents a subfamily of NifS-related cysteine ... |
66-468 |
3.46e-37 |
|
cysteine desulfurases, SufSfamily; This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 131034 [Multi-domain] Cd Length: 403 Bit Score: 140.87 E-value: 3.46e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDyNATTPLEPE-VIQAVTEAMKEAWGNPS-SSYVSGRKAKDIINAARASLAKMIGGK-PQDIIFTSGGTESNNLVIH 142
Cdd:TIGR01979 20 VYLD-SAATSQKPQqVIDAVAEYYRNSNANVHrGIHTLSVRATEAYEAVREKVAKFINAAsDEEIVFTRGTTESINLVAY 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 143 SMVRCFHEqqtlKGNMVdqhspeegtrphfITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKvNGQAEVEDILAAVRPTT 222
Cdd:TIGR01979 99 SWGDSNLK----AGDEI-------------VISEMEHHANIVPWQLLAERTGATLKFIPLDD-DGTLDLDDLEKLLTEKT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 223 CLVTIMLANNETGVIMPVSEISRRIKALNQIraasglprVLVhtDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGA 301
Cdd:TIGR01979 161 KLVAITHVSNVLGTVNPVEEIAKLAHQVGAK--------VLV--DGAQAVPHMPVDVQALDCDFYVFSGHKMYGPTgIGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 302 LYvrgvGK---LTPLYPMLFGGG-------QE-------WNFRPGTENTPMIAGLGKAADLVSE-NCETYEAHMRDIRDY 363
Cdd:TIGR01979 231 LY----GKeelLEQMPPFLGGGEmiaevsfEEttyneapHKFEAGTPNIAGVIGLGAAIDYLEAiGLENIEAHEHELTAY 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 364 LEERLEAEFGKRIhLNSRfPGVERLpNTCNFSIQGsqLQGYTVlaqcRTLLASVGASCHSNHEdrpspvllsCGIPV--- 440
Cdd:TIGR01979 307 ALERLGEIPGLRI-YGPR-DAEDRG-GIISFNVEG--VHPHDV----GTILDEEGIAVRSGHH---------CAQPLmrr 368
|
410 420
....*....|....*....|....*....
gi 568909391 441 -DVARNAvRLSVGRGTTRADVDLIVQDLK 468
Cdd:TIGR01979 369 fGVPATC-RASFYIYNTEEDIDALVEALK 396
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
62-472 |
9.89e-26 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 109.07 E-value: 9.89e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 62 GPQKVYMDyNATTPLEPeviQAVTEAMKEAWGNPSSS------YVSGrKAKDIINAARASLAKMIGGK-PQDIIFTSGGT 134
Cdd:PLN02855 30 GSKLVYLD-NAATSQKP---AAVLDALQDYYEEYNSNvhrgihALSA-KATDAYELARKKVAAFINAStSREIVFTRNAT 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 135 ESNNLVIHSMVRcfheqQTLK-GNMVdqhspeegtrphfITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKvNGQAEVED 213
Cdd:PLN02855 105 EAINLVAYTWGL-----ANLKpGDEV-------------ILSVAEHHSNIVPWQLVAQKTGAVLKFVGLTP-DEVLDVEQ 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 214 ILAAVRPTTCLVTIMLANNETGVIMPVSEISRRIKALNQiraasglpRVLVhtDAAQALGKRRVDVEDLGVDFLTIVGHK 293
Cdd:PLN02855 166 LKELLSEKTKLVATHHVSNVLGSILPVEDIVHWAHAVGA--------KVLV--DACQSVPHMPVDVQTLGADFLVASSHK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 294 FYGPR-IGALYvrgvGKLTPLYPM--LFGGGQ---------------EWNFRPGtenTPMIA---GLGKAADLVSE---- 348
Cdd:PLN02855 236 MCGPTgIGFLW----GKSDLLESMppFLGGGEmisdvfldhstyappPSRFEAG---TPAIGeaiGLGAAIDYLSEigmd 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 349 NCETYEahmRDIRDYLEERLEAEFGKRIHLNSRFPGVERLPnTCNFSIQGSQLqgyTVLAqcrTLL-ASVGASCHSNHEd 427
Cdd:PLN02855 309 RIHEYE---VELGTYLYEKLSSVPGVRIYGPKPSEGVGRAA-LCAFNVEGIHP---TDLS---TFLdQQHGVAIRSGHH- 377
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 568909391 428 RPSPVLLSCGIPVdvarnAVRLSVGRGTTRADVDLIVQDLKQAVA 472
Cdd:PLN02855 378 CAQPLHRYLGVNA-----SARASLYFYNTKEEVDAFIHALKDTIA 417
|
|
| PRK09295 |
PRK09295 |
cysteine desulfurase SufS; |
105-370 |
4.53e-18 |
|
cysteine desulfurase SufS;
Pssm-ID: 181766 [Multi-domain] Cd Length: 406 Bit Score: 85.96 E-value: 4.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 105 AKDIINAARASLAKMIGGK-PQDIIFTSGGTESNNLVIHSMVRcfheQQTLKGNmvdqhspeegtrpHFITCTVEHDSIR 183
Cdd:PRK09295 65 ATEKMENVRKQAALFINARsAEELVFVRGTTEGINLVANSWGN----SNVRAGD-------------NIIISEMEHHANI 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 184 LPLEHLVENQMAEVTFVPVSkVNGQAEVEDILAAVRPTTCLVTIMLANNETGVIMPVSEIsrrikaLNQIRAASGlpRVL 263
Cdd:PRK09295 128 VPWQMLCARVGAELRVIPLN-PDGTLQLETLPALFDERTRLLAITHVSNVLGTENPLAEM------IALAHQHGA--KVL 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 264 VhtDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYVRgvGKLTPLYPMLFGGGQ----------------EWNF 326
Cdd:PRK09295 199 V--DGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTgIGILYVK--EALLQEMPPWEGGGSmiatvsltegttwakaPWRF 274
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 568909391 327 RPGTENTPMIAGLGKAADLVS----ENCETYEahmRDIRDYLEERLEA 370
Cdd:PRK09295 275 EAGTPNTGGIIGLGAALDYVSalglNNIAEYE---QNLMHYALSQLES 319
|
|
| PRK10874 |
PRK10874 |
cysteine desulfurase CsdA; |
66-474 |
2.14e-17 |
|
cysteine desulfurase CsdA;
Pssm-ID: 182799 [Multi-domain] Cd Length: 401 Bit Score: 83.93 E-value: 2.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 66 VYMDyNATTPLEPeviQAVTEAMKEAWGNPS-----SSYVSGRKAKDIINAARASLAKMIGG-KPQDIIFTSGGTESNNL 139
Cdd:PRK10874 21 VYLD-SAATALKP---QAVIEATQQFYSLSAgnvhrSQFAAAQRLTARYEAAREQVAQLLNApDAKNIVWTRGTTESINL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 140 VIHSMVRcfheqqtlkgnmvdqhspeegtrPHF------ITCTVEHDSIRLPLEHLVENQMAEVTFVPVskvnGQAEVED 213
Cdd:PRK10874 97 VAQSYAR-----------------------PRLqpgdeiIVSEAEHHANLVPWLMVAQQTGAKVVKLPL----GADRLPD 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 214 IlaAVRPTtclvtimLANNETgvimpvseisrRIKALNQIRAASG----LPRV---------LVHTDAAQALGKRRVDVE 280
Cdd:PRK10874 150 V--DLLPE-------LITPRT-----------RILALGQMSNVTGgcpdLARAitlahqagmVVMVDGAQGAVHFPADVQ 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 281 DLGVDFLTIVGHKFYGPR-IGALYvrgvGK---LTPLYPMLfGGGQ---------------EWNFRPGTENTPMIAGLGK 341
Cdd:PRK10874 210 ALDIDFYAFSGHKLYGPTgIGVLY----GKselLEAMSPWQ-GGGKmltevsfdgftpqsaPWRFEAGTPNVAGVIGLSA 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 342 AAD-LVSENCETYEAHMRDIRDYLEERLeaefgkrihlnSRFPGVErlpntcNFSIQGSQLQGYTV-------LAqcrTL 413
Cdd:PRK10874 285 ALEwLADIDINQAESWSRSLATLAEDAL-----------AKLPGFR------SFRCQDSSLLAFDFagvhhsdLV---TL 344
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568909391 414 LASVGASCHSNHEdRPSPVLLSCGIPvdvarNAVRLSVGRGTTRADVDLIVQDLKQAVAQL 474
Cdd:PRK10874 345 LAEYGIALRAGQH-CAQPLLAALGVT-----GTLRASFAPYNTQSDVDALVNAVDRALELL 399
|
|
| f2_encap_cargo1 |
NF041166 |
family 2A encapsulin nanocompartment cargo protein cysteine desulfurase; Capsid-like ... |
111-354 |
7.55e-09 |
|
family 2A encapsulin nanocompartment cargo protein cysteine desulfurase; Capsid-like encapsulin nanocompartments are commonly found in bacteria and archaea. Encapsulin nanocompartments, which are assembled from shell proteins, encapsulate various cargo proteins, typically peroxidases or ferritin-like proteins, to protect cells from oxidative stress caused by peroxide. Proteins of this family are cysteine desulfurases with an additional N-terminal encapsulation targeting sequence (~200 aa) that is necessary and sufficient for compartmentalization.
Pssm-ID: 469077 [Multi-domain] Cd Length: 623 Bit Score: 57.94 E-value: 7.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 111 AARASLAKMIG-GKPQDIIFTSGGTESNNLVIHSMVRcfheqQTLKgnmvdqhspeEGtrphfitctvehDSIRLP-LEH 188
Cdd:NF041166 293 GAREKVRRFIGaPSVDEIIFVRGTTEAINLVAKSWGR-----QNIG----------AG------------DEIIVShLEH 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 189 ---LVE-NQMAEVT-----FVPVSKvNGQ---AEVEDILAavrPTTCLVTIMLANNETGVIMPVSEI---SRRIKAlnqi 253
Cdd:NF041166 346 hanIVPwQQLAQETgaklrVIPVDD-SGQillDEYAKLLN---PRTKLVSVTQVSNALGTVTPVKEIialAHRAGA---- 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 254 raasglpRVLVhtDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYvrgvGKL-----TPLYPmlfGGGqewN-- 325
Cdd:NF041166 418 -------KVLV--DGAQSVSHMPVDVQALDADFFVFSGHKVFGPTgIGVVY----GKRdlleaMPPWQ---GGG---Nmi 478
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 568909391 326 ----------------FRPGTENtpmIA---GLGKAADLVS----ENCETYE 354
Cdd:NF041166 479 advtfektvyqpapnrFEAGTGN---IAdavGLGAALDYVErigiENIARYE 527
|
|
| DOPA_deC_like |
cd06450 |
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
74-470 |
9.30e-08 |
|
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.
Pssm-ID: 99743 [Multi-domain] Cd Length: 345 Bit Score: 53.75 E-value: 9.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 74 TPLEPEVIQAVTEAM-KEAWGNPSSSYVSGRKAKDIInaaRASLAKMIGGKPQDI--IFTSGGTESNNLVIHSM-VRCFH 149
Cdd:cd06450 7 TTMDPPALLLEMLTSaKNAIDFTWDESPAATEMEAEV---VNWLAKLFGLPSEDAdgVFTSGGSESNLLALLAArDRARK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 150 EQQTLkgnmvdqhSPEEGTRPHFITCTVEHDSIRLPLEHLvenqMAEVTFVPVSKvNGQAEVEDILAAV--RPTTCLVTI 227
Cdd:cd06450 84 RLKAG--------GGRGIDKLVIVCSDQAHVSVEKAAAYL----DVKVRLVPVDE-DGRMDPEALEAAIdeDKAEGLNPI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 228 MLA----NNETGVIMPvseisrrIKALNQIRAASGLPrvlVHTDAAQALG------KRRVD--VEdlGVDFLTIVGHKFY 295
Cdd:cd06450 151 MVVatagTTDTGAIDP-------LEEIADLAEKYDLW---LHVDAAYGGFllpfpePRHLDfgIE--RVDSISVDPHKYG 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 296 G--PRIGALYVRGVGkltpLYPMLfgggqewnFRPGTENtpmiaglgkaadlvsencetYEAHMRDIRD---YLEERLEA 370
Cdd:cd06450 219 LvpLGCSAVLVRALK----LWATL--------RRFGRDG--------------------YGEHIDRIVDlakYLAELIRA 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568909391 371 EfgKRIHLNsrfpGVERLPNTCnFSIQGSQLQGYTVLAQCRTLLASVGAscHSNHEDRPSPvllscgipvdvarNAVRLS 450
Cdd:cd06450 267 D--PGFELL----GEPNLSLVC-FRLKPSVKLDELNYDLSDRLNERGGW--HVPATTLGGP-------------NVLRFV 324
|
410 420
....*....|....*....|.
gi 568909391 451 VGRG-TTRADVDLIVQDLKQA 470
Cdd:cd06450 325 VTNPlTTRDDADALLEDIERA 345
|
|
| |
