|
Name |
Accession |
Description |
Interval |
E-value |
| HELP |
pfam03451 |
HELP motif; The founding member of the EMAP protein family is the 75 kDa Echinoderm ... |
160-228 |
1.99e-34 |
|
HELP motif; The founding member of the EMAP protein family is the 75 kDa Echinoderm Microtubule-Associated Protein, so-named for its abundance in sea urchin, sand dollar and starfish eggs. The Hydrophobic EMAP-Like Protein (HELP) motif was identified initially in the human EMAP-Like Protein 2 (EML2) and subsequently in the entire EMAP Protein family. The HELP motif is approximately 60-70 amino acids in length and is conserved amongst metazoans. Although the HELP motif is hydrophobic, there is no evidence that EMAP-Like Proteins are membrane-associated. All members of the EMAP-Like Protein family, identified to-date, are constructed with an amino terminal HELP motif followed by a WD domain. In C. elegans, EMAP-Like Protein-1 (ELP-1) is required for touch sensation indicating that ELP-1 may play a role in mechanosensation. The localization of ELP-1 to microtubules and adhesion sites implies that ELP-1 may transmit forces between the body surface and the touch receptor neurons.
Pssm-ID: 460922 Cd Length: 72 Bit Score: 125.74 E-value: 1.99e-34
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578802837 160 KMFMRGRPITMFIPSD-VDNYD-DIRTELPPEKLKLEWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFN 228
Cdd:pfam03451 1 KMAIRGRPGAVYPPSNyYPKDDlDQKKEPPDKKLKLEWVYGYRGKDCRSNLYYLPTGEIVYFTAAVVVLYD 71
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
434-795 |
3.25e-27 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 112.43 E-value: 3.25e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 434 SKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDhdlnpereievpdqygtiravaegkadqflvgtsrnfilrgTFN 513
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWD-----------------------------------------LET 40
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 514 DGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNSMEHRLEWTrLVdepGH-----CADFHPSGTVVAIGTHSGR 588
Cdd:cd00200 41 GELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRT-LT---GHtsyvsSVAFSPDGRILSSSSRDKT 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 589 WFVLDAETRDLVSI---HTDgneqlSVM--RYSIDGTFLAVGSHDNFIYLYvvseNGRKYSRYGRCTGHSSYITHLDWSP 663
Cdd:cd00200 117 IKVWDVETGKCLTTlrgHTD-----WVNsvAFSPDGTFVASSSQDGTIKLW----DLRTGKCVATLTGHTGEVNSVAFSP 187
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 664 DNKYIMSNSGDYEILYWDIPNGcklirnrsdckdidwttyTCVLGFQVFGVWpegsdgtdINALVRSHNRKVIAVADDFC 743
Cdd:cd00200 188 DGEKLLSSSSDGTIKLWDLSTG------------------KCLGTLRGHENG--------VNSVAFSPDGYLLASGSEDG 241
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 578802837 744 KVHLFQypcSKAKAPSHKYSAHSSHVTNVSFtHNDSHLISTGGKDMSIIQWK 795
Cdd:cd00200 242 TIRVWD---LRTGECVQTLSGHTNSVTSLAW-SPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
440-796 |
8.00e-27 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 113.85 E-value: 8.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 440 HDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDlNPEREIEVPDQYGTIRAVA---EGKadQFLVGTSRNFILRGTFNDGF 516
Cdd:COG2319 77 HTAAVLSVAFSPDGRLLASASADGTVRLWDLA-TGLLLRTLTGHTGAVRSVAfspDGK--TLASGSADGTVRLWDLATGK 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 517 QI-EVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNSMEHRLEWT-RLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDA 594
Cdd:COG2319 154 LLrTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTlTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDL 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 595 ETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVsENGRKYSRYgrcTGHSSYITHLDWSPDNKYIMSNSGD 674
Cdd:COG2319 234 ATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDL-ATGELLRTL---TGHSGGVNSVAFSPDGKLLASGSDD 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 675 YEILYWDIPNGcKLIRnrsdckdidwttytcvlgfqvfgvWPEGSDGtDINALVRSHNRKVIAVADDFCKVHLFQypcSK 754
Cdd:COG2319 310 GTVRLWDLATG-KLLR------------------------TLTGHTG-AVRSVAFSPDGKTLASGSDDGTVRLWD---LA 360
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 578802837 755 AKAPSHKYSAHSSHVTNVSFTHNDSHLIStGGKDMSIIQWKL 796
Cdd:COG2319 361 TGELLRTLTGHTGAVTSVAFSPDGRTLAS-GSADGTVRLWDL 401
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
247-684 |
4.27e-26 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 111.93 E-value: 4.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 247 LAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIigLGTFERGVGCLDFSKADSGvhlcIIDDSNEHMLTVW 326
Cdd:COG2319 32 LLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLAT--LLGHTAAVLSVAFSPDGRL----LASASADGTVRLW 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 327 DWQKKAKGAEIKTTNEVVLAVEFHPtDANTIITCGKSH-IFFWTW-SGNSLTRKQGifgkyeKPKFVQCLAFLGNGDVL- 403
Cdd:COG2319 106 DLATGLLLRTLTGHTGAVRSVAFSP-DGKTLASGSADGtVRLWDLaTGKLLRTLTG------HSGAVTSVAFSPDGKLLa 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 404 TGDSGGVMLIWSKTTVEPTpgkgpkgvyqisKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDhdlnpereievpdq 483
Cdd:COG2319 179 SGSDDGTVRLWDLATGKLL------------RTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD-------------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 484 ygtiraVAEGKADQFLvgtsrnfilrgtfndgfqievQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNsmehrLEWTRL 563
Cdd:COG2319 233 ------LATGKLLRTL---------------------TGHSGSVRSVAFSPDGRLLASGSADGTVRLWD-----LATGEL 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 564 VDEPGHCAD------FHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYvvs 637
Cdd:COG2319 281 LRTLTGHSGgvnsvaFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLW--- 357
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 578802837 638 eNGRKYSRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPN 684
Cdd:COG2319 358 -DLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
235-588 |
9.83e-20 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 90.47 E-value: 9.83e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 235 RHYLGHTDCVKCLAIHPDKIRIATGqiagvDKDGRplqphVRVWDSVTLStlQIIGLGTFERGVGCLDFSkADSGvhlCI 314
Cdd:cd00200 3 RTLKGHTGGVTCVAFSPDGKLLATG-----SGDGT-----IKVWDLETGE--LLRTLKGHTGPVRDVAAS-ADGT---YL 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 315 IDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTdaNTIITCGKSH--IFFWTW-SGNSLTRKQGIFGkyekpkFV 391
Cdd:cd00200 67 ASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPD--GRILSSSSRDktIKVWDVeTGKCLTTLRGHTD------WV 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 392 QCLAFLGNGDVLTGDSG-GVMLIWSKTTVEPTpgkgpkgvyqisKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDH 470
Cdd:cd00200 139 NSVAFSPDGTFVASSSQdGTIKLWDLRTGKCV------------ATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDL 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 471 dlnpereievpdqygtiravaegkadqflvgtsRNFILRGTFndgfqievQGHTDELWGLATHPFKDLLLTCAQDRQVCL 550
Cdd:cd00200 207 ---------------------------------STGKCLGTL--------RGHENGVNSVAFSPDGYLLASGSEDGTIRV 245
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 578802837 551 WNsMEHRLEWTRLV--DEPGHCADFHPSGTVVAIGTHSGR 588
Cdd:cd00200 246 WD-LRTGECVQTLSghTNSVTSLAWSPDGKRLASGSADGT 284
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
649-681 |
8.89e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.37 E-value: 8.89e-05
10 20 30
....*....|....*....|....*....|...
gi 578802837 649 CTGHSSYITHLDWSPDNKYIMSNSGDYEILYWD 681
Cdd:smart00320 8 LKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
650-681 |
1.30e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 37.32 E-value: 1.30e-03
10 20 30
....*....|....*....|....*....|..
gi 578802837 650 TGHSSYITHLDWSPDNKYIMSNSGDYEILYWD 681
Cdd:pfam00400 8 EGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| HELP |
pfam03451 |
HELP motif; The founding member of the EMAP protein family is the 75 kDa Echinoderm ... |
160-228 |
1.99e-34 |
|
HELP motif; The founding member of the EMAP protein family is the 75 kDa Echinoderm Microtubule-Associated Protein, so-named for its abundance in sea urchin, sand dollar and starfish eggs. The Hydrophobic EMAP-Like Protein (HELP) motif was identified initially in the human EMAP-Like Protein 2 (EML2) and subsequently in the entire EMAP Protein family. The HELP motif is approximately 60-70 amino acids in length and is conserved amongst metazoans. Although the HELP motif is hydrophobic, there is no evidence that EMAP-Like Proteins are membrane-associated. All members of the EMAP-Like Protein family, identified to-date, are constructed with an amino terminal HELP motif followed by a WD domain. In C. elegans, EMAP-Like Protein-1 (ELP-1) is required for touch sensation indicating that ELP-1 may play a role in mechanosensation. The localization of ELP-1 to microtubules and adhesion sites implies that ELP-1 may transmit forces between the body surface and the touch receptor neurons.
Pssm-ID: 460922 Cd Length: 72 Bit Score: 125.74 E-value: 1.99e-34
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578802837 160 KMFMRGRPITMFIPSD-VDNYD-DIRTELPPEKLKLEWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFN 228
Cdd:pfam03451 1 KMAIRGRPGAVYPPSNyYPKDDlDQKKEPPDKKLKLEWVYGYRGKDCRSNLYYLPTGEIVYFTAAVVVLYD 71
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
434-795 |
3.25e-27 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 112.43 E-value: 3.25e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 434 SKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDhdlnpereievpdqygtiravaegkadqflvgtsrnfilrgTFN 513
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWD-----------------------------------------LET 40
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 514 DGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNSMEHRLEWTrLVdepGH-----CADFHPSGTVVAIGTHSGR 588
Cdd:cd00200 41 GELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRT-LT---GHtsyvsSVAFSPDGRILSSSSRDKT 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 589 WFVLDAETRDLVSI---HTDgneqlSVM--RYSIDGTFLAVGSHDNFIYLYvvseNGRKYSRYGRCTGHSSYITHLDWSP 663
Cdd:cd00200 117 IKVWDVETGKCLTTlrgHTD-----WVNsvAFSPDGTFVASSSQDGTIKLW----DLRTGKCVATLTGHTGEVNSVAFSP 187
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 664 DNKYIMSNSGDYEILYWDIPNGcklirnrsdckdidwttyTCVLGFQVFGVWpegsdgtdINALVRSHNRKVIAVADDFC 743
Cdd:cd00200 188 DGEKLLSSSSDGTIKLWDLSTG------------------KCLGTLRGHENG--------VNSVAFSPDGYLLASGSEDG 241
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 578802837 744 KVHLFQypcSKAKAPSHKYSAHSSHVTNVSFtHNDSHLISTGGKDMSIIQWK 795
Cdd:cd00200 242 TIRVWD---LRTGECVQTLSGHTNSVTSLAW-SPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
440-796 |
8.00e-27 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 113.85 E-value: 8.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 440 HDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDlNPEREIEVPDQYGTIRAVA---EGKadQFLVGTSRNFILRGTFNDGF 516
Cdd:COG2319 77 HTAAVLSVAFSPDGRLLASASADGTVRLWDLA-TGLLLRTLTGHTGAVRSVAfspDGK--TLASGSADGTVRLWDLATGK 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 517 QI-EVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNSMEHRLEWT-RLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDA 594
Cdd:COG2319 154 LLrTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTlTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDL 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 595 ETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVsENGRKYSRYgrcTGHSSYITHLDWSPDNKYIMSNSGD 674
Cdd:COG2319 234 ATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDL-ATGELLRTL---TGHSGGVNSVAFSPDGKLLASGSDD 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 675 YEILYWDIPNGcKLIRnrsdckdidwttytcvlgfqvfgvWPEGSDGtDINALVRSHNRKVIAVADDFCKVHLFQypcSK 754
Cdd:COG2319 310 GTVRLWDLATG-KLLR------------------------TLTGHTG-AVRSVAFSPDGKTLASGSDDGTVRLWD---LA 360
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 578802837 755 AKAPSHKYSAHSSHVTNVSFTHNDSHLIStGGKDMSIIQWKL 796
Cdd:COG2319 361 TGELLRTLTGHTGAVTSVAFSPDGRTLAS-GSADGTVRLWDL 401
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
247-684 |
4.27e-26 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 111.93 E-value: 4.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 247 LAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIigLGTFERGVGCLDFSKADSGvhlcIIDDSNEHMLTVW 326
Cdd:COG2319 32 LLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLAT--LLGHTAAVLSVAFSPDGRL----LASASADGTVRLW 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 327 DWQKKAKGAEIKTTNEVVLAVEFHPtDANTIITCGKSH-IFFWTW-SGNSLTRKQGifgkyeKPKFVQCLAFLGNGDVL- 403
Cdd:COG2319 106 DLATGLLLRTLTGHTGAVRSVAFSP-DGKTLASGSADGtVRLWDLaTGKLLRTLTG------HSGAVTSVAFSPDGKLLa 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 404 TGDSGGVMLIWSKTTVEPTpgkgpkgvyqisKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDhdlnpereievpdq 483
Cdd:COG2319 179 SGSDDGTVRLWDLATGKLL------------RTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD-------------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 484 ygtiraVAEGKADQFLvgtsrnfilrgtfndgfqievQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNsmehrLEWTRL 563
Cdd:COG2319 233 ------LATGKLLRTL---------------------TGHSGSVRSVAFSPDGRLLASGSADGTVRLWD-----LATGEL 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 564 VDEPGHCAD------FHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYvvs 637
Cdd:COG2319 281 LRTLTGHSGgvnsvaFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLW--- 357
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 578802837 638 eNGRKYSRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPN 684
Cdd:COG2319 358 -DLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
388-681 |
2.12e-23 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 101.26 E-value: 2.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 388 PKFVQCLAFLGNGDVL-TGDSGGVMLIWSKTTVEPtpgkgpkgvyqiSKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKII 466
Cdd:cd00200 9 TGGVTCVAFSPDGKLLaTGSGDGTIKVWDLETGEL------------LRTLKGHTGPVRDVAASADGTYLASGSSDKTIR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 467 LWD-HDLNPEREIEVPDQYgtIRAVAEGKADQFLVGTSRNFILR--GTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCA 543
Cdd:cd00200 77 LWDlETGECVRTLTGHTSY--VSSVAFSPDGRILSSSSRDKTIKvwDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 544 QDRQVCLWNSMEHRLEWTRlvdePGH-----CADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSID 618
Cdd:cd00200 155 QDGTIKLWDLRTGKCVATL----TGHtgevnSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPD 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578802837 619 GTFLAVGSHDNFIYLYvvseNGRKYSRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWD 681
Cdd:cd00200 231 GYLLASGSEDGTIRVW----DLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
323-685 |
3.18e-23 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 103.07 E-value: 3.18e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 323 LTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGIFGKyekpkFVQCLAFLGNGDV 402
Cdd:COG2319 18 LALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTA-----AVLSVAFSPDGRL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 403 L-TGDSGGVMLIWSKTTVEPTPgkgpkgvyqiskQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWD-HDLNPEREIEV 480
Cdd:COG2319 93 LaSASADGTVRLWDLATGLLLR------------TLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDlATGKLLRTLTG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 481 PDqyGTIRAVAEGKADQFLVGTSRNFILR--GTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNsMEHRL 558
Cdd:COG2319 161 HS--GAVTSVAFSPDGKLLASGSDDGTVRlwDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD-LATGK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 559 EWTRLVDEPG--HCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVV 636
Cdd:COG2319 238 LLRTLTGHSGsvRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDL 317
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 578802837 637 SEngrkysryGRC----TGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNG 685
Cdd:COG2319 318 AT--------GKLlrtlTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATG 362
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
451-796 |
5.79e-21 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 96.52 E-value: 5.79e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 451 RNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDG-FQIEVQGHTDELWG 529
Cdd:COG2319 4 ADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGaLLATLLGHTAAVLS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 530 LATHPFKDLLLTCAQDRQVCLWN-SMEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNE 608
Cdd:COG2319 84 VAFSPDGRLLASASADGTVRLWDlATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 609 QLSVMRYSIDGTFLAVGSHDNFIYLYVVsENGRKYSRYgrcTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGcKL 688
Cdd:COG2319 164 AVTSVAFSPDGKLLASGSDDGTVRLWDL-ATGKLLRTL---TGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATG-KL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 689 IRnrsdckdidwttytcvlgfqvfgvwPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQypcSKAKAPSHKYSAHSSH 768
Cdd:COG2319 239 LR-------------------------TLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWD---LATGELLRTLTGHSGG 290
|
330 340
....*....|....*....|....*...
gi 578802837 769 VTNVSFTHNDSHLIStGGKDMSIIQWKL 796
Cdd:COG2319 291 VNSVAFSPDGKLLAS-GSDDGTVRLWDL 317
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
235-588 |
9.83e-20 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 90.47 E-value: 9.83e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 235 RHYLGHTDCVKCLAIHPDKIRIATGqiagvDKDGRplqphVRVWDSVTLStlQIIGLGTFERGVGCLDFSkADSGvhlCI 314
Cdd:cd00200 3 RTLKGHTGGVTCVAFSPDGKLLATG-----SGDGT-----IKVWDLETGE--LLRTLKGHTGPVRDVAAS-ADGT---YL 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 315 IDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTdaNTIITCGKSH--IFFWTW-SGNSLTRKQGIFGkyekpkFV 391
Cdd:cd00200 67 ASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPD--GRILSSSSRDktIKVWDVeTGKCLTTLRGHTD------WV 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 392 QCLAFLGNGDVLTGDSG-GVMLIWSKTTVEPTpgkgpkgvyqisKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDH 470
Cdd:cd00200 139 NSVAFSPDGTFVASSSQdGTIKLWDLRTGKCV------------ATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDL 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 471 dlnpereievpdqygtiravaegkadqflvgtsRNFILRGTFndgfqievQGHTDELWGLATHPFKDLLLTCAQDRQVCL 550
Cdd:cd00200 207 ---------------------------------STGKCLGTL--------RGHENGVNSVAFSPDGYLLASGSEDGTIRV 245
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 578802837 551 WNsMEHRLEWTRLV--DEPGHCADFHPSGTVVAIGTHSGR 588
Cdd:cd00200 246 WD-LRTGECVQTLSghTNSVTSLAWSPDGKRLASGSADGT 284
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
212-552 |
9.93e-19 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 89.59 E-value: 9.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 212 PTGKIvyfIASV-----VVLFNYEERTQRHYL-GHTDCVKCLAIHPDKIRIATGqiagvDKDGRplqphVRVWDSVTLST 285
Cdd:COG2319 130 PDGKT---LASGsadgtVRLWDLATGKLLRTLtGHSGAVTSVAFSPDGKLLASG-----SDDGT-----VRLWDLATGKL 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 286 LQIigLGTFERGVGCLDFSkADSGVhlcIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPtDANTIITCGKSH- 364
Cdd:COG2319 197 LRT--LTGHTGAVRSVAFS-PDGKL---LASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSP-DGRLLASGSADGt 269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 365 IFFWTW-SGNSLTRKQGIFGKyekpkfVQCLAFLGNGDVL-TGDSGGVMLIWSKTTVEPTpgkgpkgvyqisKQIKAHDG 442
Cdd:COG2319 270 VRLWDLaTGELLRTLTGHSGG------VNSVAFSPDGKLLaSGSDDGTVRLWDLATGKLL------------RTLTGHTG 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 443 SVFTLCQMRNGMLLTGGGKDRKIILWDhdlnpereievpdqygtiraVAEGKADQFLvgtsrnfilrgtfndgfqievQG 522
Cdd:COG2319 332 AVRSVAFSPDGKTLASGSDDGTVRLWD--------------------LATGELLRTL---------------------TG 370
|
330 340 350
....*....|....*....|....*....|
gi 578802837 523 HTDELWGLATHPFKDLLLTCAQDRQVCLWN 552
Cdd:COG2319 371 HTGAVTSVAFSPDGRTLASGSADGTVRLWD 400
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
489-796 |
6.90e-18 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 86.89 E-value: 6.90e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 489 AVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNSMEHRLEWTRLV-DEP 567
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGhTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 568 GHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVsENGRKYSRYg 647
Cdd:COG2319 81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDL-ATGKLLRTL- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 648 rcTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGcKLIRnrsdckdidwttytcvlgfqvfgVWPEGSDGtdINAL 727
Cdd:COG2319 159 --TGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATG-KLLR-----------------------TLTGHTGA--VRSV 210
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578802837 728 VRSHNRKVIAVADDFCKVHLFQypcSKAKAPSHKYSAHSSHVTNVSFTHnDSHLISTGGKDMSIIQWKL 796
Cdd:COG2319 211 AFSPDGKLLASGSADGTVRLWD---LATGKLLRTLTGHSGSVRSVAFSP-DGRLLASGSADGTVRLWDL 275
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
226-552 |
4.06e-17 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 82.77 E-value: 4.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 226 LFNYEERTQRHYL-GHTDCVKCLAIHPDKIRIATGqiaGVDKDgrplqphVRVWDSVTLSTLQIigLGTFERGVGCLDFS 304
Cdd:cd00200 35 VWDLETGELLRTLkGHTGPVRDVAASADGTYLASG---SSDKT-------IRLWDLETGECVRT--LTGHTSYVSSVAFS 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 305 KaDSGVHLCIIDDSNehmLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTdaNTIITCGKS--HIFFWtwSGNSLTRKQGIF 382
Cdd:cd00200 103 P-DGRILSSSSRDKT---IKVWDVETGKCLTTLRGHTDWVNSVAFSPD--GTFVASSSQdgTIKLW--DLRTGKCVATLT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 383 GKYekpKFVQCLAFLGNG-DVLTGDSGGVMLIWSKTTVeptpgkgpkgvyQISKQIKAHDGSVFTLCQMRNGMLLTGGGK 461
Cdd:cd00200 175 GHT---GEVNSVAFSPDGeKLLSSSSDGTIKLWDLSTG------------KCLGTLRGHENGVNSVAFSPDGYLLASGSE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 462 DRKIILWDhdlnpereievpdqygtiravaegkadqflvgtSRNFILRGTFndgfqievQGHTDELWGLATHPFKDLLLT 541
Cdd:cd00200 240 DGTIRVWD---------------------------------LRTGECVQTL--------SGHTNSVTSLAWSPDGKRLAS 278
|
330
....*....|.
gi 578802837 542 CAQDRQVCLWN 552
Cdd:cd00200 279 GSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
519-796 |
1.07e-14 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 75.45 E-value: 1.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 519 EVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNsMEHRLEWTRLVdepGHcadfhpsgtvvaigTHSGRWFVLDAetrd 598
Cdd:cd00200 4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWD-LETGELLRTLK---GH--------------TGPVRDVAASA---- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 599 lvsihtdgneqlsvmrysiDGTFLAVGSHDNFIYLYVVsENGRKYSRYgrcTGHSSYITHLDWSPDNKYIMSNSGDYEIL 678
Cdd:cd00200 62 -------------------DGTYLASGSSDKTIRLWDL-ETGECVRTL---TGHTSYVSSVAFSPDGRILSSSSRDKTIK 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 679 YWDIPNGcKLIRNRSDCKDidwttytcvlgfqvfgvwpegsdgtDINALVRSHNRKVIAVADDFCKVHLFQYPCSKakaP 758
Cdd:cd00200 119 VWDVETG-KCLTTLRGHTD-------------------------WVNSVAFSPDGTFVASSSQDGTIKLWDLRTGK---C 169
|
250 260 270
....*....|....*....|....*....|....*...
gi 578802837 759 SHKYSAHSSHVTNVSFTHNDSHLISTGGkDMSIIQWKL 796
Cdd:cd00200 170 VATLTGHTGEVNSVAFSPDGEKLLSSSS-DGTIKLWDL 206
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
559-679 |
2.45e-05 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 45.43 E-value: 2.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 559 EWTRLVDEPGHCAD--FHPSGTVVAIGT-HSGRW--FVLDAETRDLVSIHTDGNEQLSVmRYSIDGTFLAVGSH-DNFIY 632
Cdd:COG0823 22 EPRRLTNSPGIDTSpaWSPDGRRIAFTSdRGGGPqiYVVDADGGEPRRLTFGGGYNASP-SWSPDGKRLAFVSRsDGRFD 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 578802837 633 LYVVSENGRKYSRYGRCTGHSSyithldWSPDNKYIM--SNSGDYEILY 679
Cdd:COG0823 101 IYVLDLDGGAPRRLTDGPGSPS------WSPDGRRIVfsSDRGGRPDLY 143
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
649-681 |
8.89e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.37 E-value: 8.89e-05
10 20 30
....*....|....*....|....*....|...
gi 578802837 649 CTGHSSYITHLDWSPDNKYIMSNSGDYEILYWD 681
Cdd:smart00320 8 LKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
650-681 |
1.30e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 37.32 E-value: 1.30e-03
10 20 30
....*....|....*....|....*....|..
gi 578802837 650 TGHSSYITHLDWSPDNKYIMSNSGDYEILYWD 681
Cdd:pfam00400 8 EGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
521-552 |
1.79e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 36.94 E-value: 1.79e-03
10 20 30
....*....|....*....|....*....|..
gi 578802837 521 QGHTDELWGLATHPFKDLLLTCAQDRQVCLWN 552
Cdd:pfam00400 8 EGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
521-552 |
2.38e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 36.52 E-value: 2.38e-03
10 20 30
....*....|....*....|....*....|..
gi 578802837 521 QGHTDELWGLATHPFKDLLLTCAQDRQVCLWN 552
Cdd:smart00320 9 KGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
579-685 |
4.46e-03 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 38.88 E-value: 4.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578802837 579 VVAIGTHSGRW--FVLDAETRDLVSIhTDGNEQLSVMRYSIDGTFLAVGSHDNFIY-LYVVSENGRKYSRYgrcTGHSSY 655
Cdd:COG0823 1 LAFTLSRDGNSdiYVVDLDGGEPRRL-TNSPGIDTSPAWSPDGRRIAFTSDRGGGPqIYVVDADGGEPRRL---TFGGGY 76
|
90 100 110
....*....|....*....|....*....|...
gi 578802837 656 ITHLDWSPDNKYIM---SNSGDYEILYWDIPNG 685
Cdd:COG0823 77 NASPSWSPDGKRLAfvsRSDGRFDIYVLDLDGG 109
|
|
|