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Conserved domains on  [gi|578805993|ref|XP_006713173|]
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golgin subfamily A member 4 isoform X8 [Homo sapiens]

Protein Classification

SMC_prok_B and Grip domain-containing protein( domain architecture ID 13279029)

protein containing domains PTZ00121, SMC_prok_B, and Grip

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1466-2161 2.30e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1466 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1545
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1546 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1622
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1623 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1702
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1703 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1767
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1768 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1821
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1822 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1891
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1892 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1971
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1972 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2051
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2052 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK---YQQKLEQEEnpgndnVTIMEL 2128
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKlaqLELRLEGLE------VRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 578805993  2129 QTQLAQK--------TTLISDSKLKEQEFREQIHNLEDRLK 2161
Cdd:TIGR02168  942 QERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 761-1685 2.57e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   761 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 836
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   837 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 916
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   917 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 996
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   997 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1076
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1077 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1156
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1157 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1232
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1233 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1312
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1313 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1392
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1393 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1468
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1469 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1548
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1549 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1625
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578805993  1626 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1685
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
PTZ00121 super family cl31754
MAEBL; Provisional
 335-1017 4.22e-13

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 4.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  335 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 414
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  415 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 492
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  493 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 569
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  570 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 645
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  646 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 723
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  724 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 803
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  804 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 882
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  883 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 962
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 578805993  963 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1017
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2192-2235 5.48e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.48e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 578805993   2192 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2235
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1466-2161 2.30e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1466 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1545
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1546 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1622
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1623 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1702
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1703 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1767
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1768 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1821
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1822 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1891
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1892 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1971
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1972 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2051
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2052 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK---YQQKLEQEEnpgndnVTIMEL 2128
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKlaqLELRLEGLE------VRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 578805993  2129 QTQLAQK--------TTLISDSKLKEQEFREQIHNLEDRLK 2161
Cdd:TIGR02168  942 QERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 761-1685 2.57e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   761 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 836
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   837 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 916
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   917 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 996
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   997 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1076
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1077 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1156
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1157 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1232
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1233 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1312
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1313 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1392
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1393 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1468
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1469 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1548
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1549 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1625
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578805993  1626 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1685
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
PTZ00121 PTZ00121
MAEBL; Provisional
 335-1017 4.22e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 4.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  335 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 414
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  415 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 492
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  493 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 569
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  570 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 645
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  646 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 723
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  724 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 803
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  804 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 882
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  883 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 962
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 578805993  963 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1017
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 299-821 4.97e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 4.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  299 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE----------RLQELEKIKDLHMAEKTKLITQL 368
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyellaELARLEQDIARLEERRRELEERL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  369 RDAKNLIEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE 448
Cdd:COG1196   319 EELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  449 ARRKLK--AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 526
Cdd:COG1196   398 LAAQLEelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  527 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 606
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  607 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 686
Cdd:COG1196   558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  687 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 766
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 578805993  767 IQRTEKALKDQinQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 821
Cdd:COG1196   718 EEELEEEALEE--QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 307-992 1.67e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   307 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE-RLQELEKIKDLHMAEKTklitqLRDAKNLIEQLEQDKgMV 385
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLEQQK-QI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   386 IAETKRQMHETLEMKEEEIAQLRSRI-------KQMTTQGEELREQKE------KSERAAFEELEKALSTAQKTEEARRK 452
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   453 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkELARKEQELtKKLQTREREFQEQMK 532
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA-ELEELEEEL-EELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   533 VAL----EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL-------ESSLEKSLQ 601
Cdd:TIGR02168  465 ELReeleEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   602 EN-------KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK------------------- 655
Cdd:TIGR02168  545 GRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   656 ----QQYQTEMEKLREKCEQE-----KETLLKDKEIIFQAHiEEMNEKTLEK---LDVKQTELESLSSELSEVLKARHKL 723
Cdd:TIGR02168  625 vlvvDDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGS-AKTNSSILERrreIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   724 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK---HLKEHQAH 798
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   799 VENLEADIKRSEGELQQASAKLDVFQSYQSATHE-----QTKAYEEQLAQLQQKLLDLETERIL--LTKQVAEVEAQKKD 871
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlRERLESLERRIAATERRLEDLEEQIeeLSEDIESLAAEIEE 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   872 VCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVyESKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKL 951
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLEL----RLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 578805993   952 SAKEDSihiLNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 992
Cdd:TIGR02168  939 DNLQER---LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
PTZ00121 PTZ00121
MAEBL; Provisional
 405-1144 3.63e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.01  E-value: 3.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  405 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERiSLQQELSRVKQ 484
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  485 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREfqEQMKVALEKSQSEYLKisQEKEQQESLALEELELQK 564
Cdd:PTZ00121 1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  565 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvhlEAEKNKHNKEITVMVEKHKTElESLKHQQD 644
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEE 1313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  645 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 724
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  725 EELSVLKDQTDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQInqlelllkeRDKHLKEHQAHVENL 802
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEA---------KKKAEEAKKAEEAKK 1464

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  803 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV----EAQKKDVCTELDA 878
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  879 HKiQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 958
Cdd:PTZ00121 1545 KK-KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  959 HILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDA 1037
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1038 VSRLETNQKEQIESLTEVHRRElnDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1117
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAE--EENKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780

                         730       740
                  ....*....|....*....|....*..
gi 578805993 1118 KEEGVKQDTTLNELQEQLKQKSAHVNS 1144
Cdd:PTZ00121 1781 IEEELDEEDEKRRMEVDKKIKDIFDNF 1807
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 723-1046 5.04e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 5.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  723 LEEELSVLKDQTDKMK--QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 800
Cdd:COG1196   198 LERQLEPLERQAEKAEryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  801 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 880
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  881 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVekenmILQMREGQKKEIEILTQKLSAKEDSIHI 960
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAE 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  961 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1040
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512


                  ....*.
gi 578805993 1041 LETNQK 1046
Cdd:COG1196   513 ALLLAG 518
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1481-2106 6.39e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 6.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1481 KELQIQLELKSKEAYEKdeQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1560
Cdd:COG1196   216 RELKEELKELEAELLLL--KLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1561 IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN---RVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1637
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAEleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1638 KEEELKALEDRLESESAAKLAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKS 1717
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRAAAEL------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1718 VESSQSETLivprsaknvAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSshfemrcqyqeRL 1797
Cdd:COG1196   444 LEEAAEEEA---------ELEEEEEAL----------LELLAELLEEAALLEAALAELLEELAEAAA-----------RL 493

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1798 IKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENvfDDVQKTLQEKELTCQILEQKIK 1877
Cdd:COG1196   494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ--NIVVEDDEVAAAAIEYLKAAKA 571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1878 ELDSCLVRQKEVHRVEMEELTSKYEKLQA--LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1955
Cdd:COG1196   572 GRATFLPLDKIRARAALAAALARGAIGAAvdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1956 EREKQKLGKEIVRLQ-KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM 2034
Cdd:COG1196   652 EGEGGSAGGSLTGGSrRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578805993 2035 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEI----LDAREE--EMTAKVRDLQTQLEELQK 2106
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAIEEyeELEERYDFLSEQREDLEE 809
PTZ00121 PTZ00121
MAEBL; Provisional
 1410-1878 6.94e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 6.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1410 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQiQLEL 1489
Cdd:PTZ00121 1286 AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1490 KSKEAYEKDEQINLLKEELD---QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARimeledhitqktieiESLNE 1566
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK---------------KKAEE 1429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1567 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQvysMKAELETKKKELEHVNLSVKSKEEELKALE 1646
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK---KKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1647 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1726
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1727 --IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1803
Cdd:PTZ00121 1587 kkAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578805993 1804 EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE 1878
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 335-1202 3.86e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 3.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   335 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETkrqmheTLEMKEEEIAQLRSRIKQM 414
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY------LLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   415 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 494
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   495 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS--QSEYLKISQEKEQQESLALEELELQKKAILTESE 572
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   573 NKLRDLQQEAETYRTRILELESSLEKSLQENKnqskdLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 652
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEE-----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   653 VLKQQYQTEMEKLREkcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 732
Cdd:pfam02463  480 VKLQEQLELLLSRQK--LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   733 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 812
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   813 LQQASAKLDVFQSYQSATHEQTkayEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 892
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   893 QNSEMEQKVKSLTQVYESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 971
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKInEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   972 QEKKMEKVKQKAKEmqetlKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1051
Cdd:pfam02463  795 KLKAQEEELRALEE-----ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1052 LTEVHRRELNDVISIWEKKLNQQAEELQEIHE-IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1130
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKElEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578805993  1131 LQEQLKQKSAHVNSLAQDEtklKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1202
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLA---KEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 319-638 8.16e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 60.91  E-value: 8.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   319 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 394
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   395 ETLEMKEEEIAQLRSRIKQMttqgEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKtIEKTSEEERis 474
Cdd:pfam17380  361 ELERIRQEEIAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQ-IRAEQEEAR-- 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   475 lQQELSRVKQEVVDVMKKSSEEQIAK---LQKLHEKELARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKE 550
Cdd:pfam17380  434 -QREVRRLEEERAREMERVRLEEQERqqqVERLRQQEEERKRKKLELEKEKRDRkRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   551 QQESLALEELELQKKAILTESEnklrdlQQEAETYRTRILELESslEKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMV 629
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEER------RREAEEERRKQQEMEE--RRRIQEQMRKATEERSRLEAmEREREMMRQIVES 584


                   ....*....
gi 578805993   630 EKHKTELES 638
Cdd:pfam17380  585 EKARAEYEA 593
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2192-2235 5.48e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.48e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 578805993   2192 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2235
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1356-2172 3.58e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 3.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1356 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQ 1435
Cdd:pfam02463  206 AKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1436 DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE--LKSKEAYEKDEQINLLKEELDQQNK 1513
Cdd:pfam02463  286 EELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEelEKELKELEIKREAEEEEEEELEKLQ 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1514 RFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEI----ESLNEVLKNYNQQKDIEHKELVQKLQHF 1589
Cdd:pfam02463  366 EKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELarqlEDLLKEEKKEELEILEEEEESIELKQGK 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1590 QELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIA 1669
Cdd:pfam02463  446 LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRII 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1670 AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGC 1749
Cdd:pfam02463  526 SAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1750 VQKTYEE-KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKY 1828
Cdd:pfam02463  606 AQLDKATlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1829 SLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT-CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQAL 1907
Cdd:pfam02463  686 ESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADrVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1908 QQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL 1987
Cdd:pfam02463  766 KSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1988 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2067
Cdd:pfam02463  846 QKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2068 KDDDLKrtaKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQ 2147
Cdd:pfam02463  926 EAEILL---KYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEE 1002

                          810       820
                   ....*....|....*....|....*
gi 578805993  2148 EFREQIHNLEDRLKKYEKNVYATTV 2172
Cdd:pfam02463 1003 EKKKLIRAIIEETCQRLKEFLELFV 1027
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2193-2232 1.22e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 44.27  E-value: 1.22e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 578805993  2193 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2232
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1466-2161 2.30e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1466 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1545
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1546 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1622
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1623 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1702
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1703 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1767
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1768 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1821
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1822 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1891
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1892 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1971
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1972 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2051
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2052 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK---YQQKLEQEEnpgndnVTIMEL 2128
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKlaqLELRLEGLE------VRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 578805993  2129 QTQLAQK--------TTLISDSKLKEQEFREQIHNLEDRLK 2161
Cdd:TIGR02168  942 QERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 761-1685 2.57e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   761 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 836
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   837 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 916
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   917 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 996
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   997 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1076
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1077 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1156
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1157 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1232
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1233 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1312
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1313 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1392
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1393 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1468
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1469 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1548
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1549 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1625
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578805993  1626 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1685
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 941-1788 1.09e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.42  E-value: 1.09e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   941 KKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK------VKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 1014
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKreyegyELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1015 KEKQFNAKMLEMAQANsAGISDAVSRLETNQKEQIESLtEVHRRELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVA 1094
Cdd:TIGR02169  263 LEKRLEEIEQLLEELN-KKIKDLGEEEQLRVKEKIGEL-EAEIASLERSIAEKERELEDAEERLAKL-EAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1095 ELKQKIllfgcekEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1174
Cdd:TIGR02169  340 ELEREI-------EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1175 EQLVELKMLAEEDKRKVSELTSKLKTTDEEfqslkssheksnksLEDKSLEFKKLSEELaiqldiccKKTEALLEAKTNE 1254
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEE--------------KEDKALEIKKQEWKL--------EQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1255 LINISSsKTNAILSRISHCQHRttkvkealliktctVSELEAQLRQLTEEQntlnISFQQAThqlEEKENQIKSMKADIE 1334
Cdd:TIGR02169  471 LYDLKE-EYDRVEKELSKLQRE--------------LAEAEAQARASEERV----RGGRAVE---EVLKASIQGVHGTVA 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1335 SLVTEKE----ALQKEGGNQQQAA-----SEKESCITQLKkelSENINAVTLMKEELKEKKVEISSLSKQ---------L 1396
Cdd:TIGR02169  529 QLGSVGEryatAIEVAAGNRLNNVvveddAVAKEAIELLK---RRKAGRATFLPLNKMRDERRDLSILSEdgvigfavdL 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1397 TDLNVQLQNSIS------------------------------LSEKEAAI---SSLRKQYDEEKCELLDQVQDLSFKVDT 1443
Cdd:TIGR02169  606 VEFDPKYEPAFKyvfgdtlvvedieaarrlmgkyrmvtlegeLFEKSGAMtggSRAPRGGILFSRSEPAELQRLRERLEG 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1444 LSKEKISALEQVDdwsnkfsewkkKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1523
Cdd:TIGR02169  686 LKRELSSLQSELR-----------RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1524 DDKSKM---EKKESNLETELKSQTARIMELEDHITQKTI-EIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNR 1599
Cdd:TIGR02169  755 NVKSELkelEARIEELEEDLHKLEEALNDLEARLSHSRIpEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1600 VKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsesaaKLAELKRKAEQKIAAIKKQLlsqm 1679
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG-----DLKKERDELEAQLRELERKI---- 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1680 EEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQ------------EEADSQ 1747
Cdd:TIGR02169  906 EELEAQIEK-KRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEiralepvnmlaiQEYEEV 984

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 578805993  1748 GCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1788
Cdd:TIGR02169  985 LKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFE 1025
PTZ00121 PTZ00121
MAEBL; Provisional
 335-1017 4.22e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 4.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  335 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 414
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  415 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 492
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  493 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 569
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  570 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 645
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  646 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 723
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  724 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 803
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  804 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 882
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  883 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 962
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 578805993  963 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1017
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1291-2104 1.25e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.94  E-value: 1.25e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1291 VSELEAQLRQLtEEQNTLNISFQQATHQLEEKenQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSE 1370
Cdd:TIGR02168  195 LNELERQLKSL-ERQAEKAERYKELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1371 NINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQnsiSLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKIS 1450
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQQKQ---ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1451 ALEQVDDWSNKFSEWKKKAQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELdqqnkrfdclkGEMEDDKSKME 1530
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEEL----ESRLEELEEQLETLRSKVAQLELQIASLNNEI-----------ERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1531 KKESNLETELKSQTARIMELEDHITQKTIEieslnevlknynqQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1610
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAELE-------------ELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1611 ENQVYSMKAELETkkkelehvnlsvkskeeeLKALEDRLESESAAKLAELKrkaEQKIAAIKKQLLSQMEEKEEQYKKGT 1690
Cdd:TIGR02168  481 ERELAQLQARLDS------------------LERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1691 ESHLSE-LNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR------ 1763
Cdd:TIGR02168  540 EAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkals 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1764 ----------------NLTEKEKLLQRVGQEKEETVSSHF-------EMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEE 1820
Cdd:TIGR02168  620 yllggvlvvddldnalELAKKLRPGYRIVTLDGDLVRPGGvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1821 LEEKNKKYSLIVAQHVEKEggknniQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSK 1900
Cdd:TIGR02168  700 LAELRKELEELEEELEQLR------KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1901 YEKLQALQQMDGRNKPTELLEENTEEKSKSHLvqpkllSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH 1980
Cdd:TIGR02168  774 EEELAEAEAEIEELEAQIEQLKEELKALREAL------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1981 QQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE---- 2056
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKlaql 927

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 578805993  2057 ---------ETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEEL 2104
Cdd:TIGR02168  928 elrleglevRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 299-821 4.97e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 4.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  299 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE----------RLQELEKIKDLHMAEKTKLITQL 368
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyellaELARLEQDIARLEERRRELEERL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  369 RDAKNLIEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE 448
Cdd:COG1196   319 EELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  449 ARRKLK--AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 526
Cdd:COG1196   398 LAAQLEelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  527 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 606
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  607 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 686
Cdd:COG1196   558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  687 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 766
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 578805993  767 IQRTEKALKDQinQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 821
Cdd:COG1196   718 EEELEEEALEE--QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 301-585 7.65e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 7.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  301 LETLQQRVKRQENLLKRCKETIQSHKEQctllTSEKEALQEQLDERLQELEKikdlhmaEKTKLITQLRDAKNLIEQLEQ 380
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAE----LAELEAELEELRLELEELEL-------ELEEAQAEEYELLAELARLEQ 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  381 DKgMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSEraafEELEKALSTAQKTEEARRKLKAEMDEQ 460
Cdd:COG1196   303 DI-ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE----EELEEAEAELAEAEEALLEAEAELAEA 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  461 IKTIEKTSEEERISLQQELSRVKQ-EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ 539
Cdd:COG1196   378 EEELEELAEELLEALRAAAELAAQlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 578805993  540 SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 585
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 567-1336 1.40e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.47  E-value: 1.40e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   567 ILTESENKLRDLQQEAET---YRtRILELESSLEKSLQENKNQSkdlavhLEAEKNKHNKEITVMVEKHKtELESLKHQQ 643
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKaerYK-ELKAELRELELALLVLRLEE------LREELEELQEELKEAEEELE-ELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   644 DALWTEKlqvlkqqyQTEMEKLREKCEQEKETLLKDKEIIfqAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKL 723
Cdd:TIGR02168  266 EEKLEEL--------RLEVSELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   724 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSiikehevsiQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 803
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEEL---------ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   804 ADIKRSEGELQQASakldvfqsyQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKdvctELDAHKIQV 883
Cdd:TIGR02168  407 ARLERLEDRRERLQ---------QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE----ELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   884 QDLMQQLEKQNSEMEQKVKSLtqvyESKLEDGNKEQEQTKQILVEKENM---------ILQMREGQKKEIE--------- 945
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLsgilgvlseLISVDEGYEAAIEaalggrlqa 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   946 ILTQKLSAKEDSIHILNEEYETK-----------FKNQEKKMEKVKQKAKEMQetLKKKLLDQEAKLKKELEN------- 1007
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRvtflpldsikgTEIQGNDREILKNIEGFLG--VAKDLVKFDPKLRKALSYllggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1008 -----TALELSQKEK-QFNAKMLEMAQANSAGISdavsrleTNQKEQIESLTEVHRRELNDVisiwEKKLNQQAEELQEI 1081
Cdd:TIGR02168  628 vddldNALELAKKLRpGYRIVTLDGDLVRPGGVI-------TGGSAKTNSSILERRREIEEL----EEKIEELEEKIAEL 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1082 hEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEV 1161
Cdd:TIGR02168  697 -EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1162 DLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEElaiqldicc 1241
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ--------- 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1242 KKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALliktctvSELEAQLRQLTEEQNTLNISFQQATHQLEE 1321
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL-------ALLRSELEELSEELRELESKRSELRRELEE 919

                          810
                   ....*....|....*
gi 578805993  1322 KENQIKSMKADIESL 1336
Cdd:TIGR02168  920 LREKLAQLELRLEGL 934
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 307-992 1.67e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   307 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE-RLQELEKIKDLHMAEKTklitqLRDAKNLIEQLEQDKgMV 385
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLEQQK-QI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   386 IAETKRQMHETLEMKEEEIAQLRSRI-------KQMTTQGEELREQKE------KSERAAFEELEKALSTAQKTEEARRK 452
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   453 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkELARKEQELtKKLQTREREFQEQMK 532
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA-ELEELEEEL-EELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   533 VAL----EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL-------ESSLEKSLQ 601
Cdd:TIGR02168  465 ELReeleEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   602 EN-------KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK------------------- 655
Cdd:TIGR02168  545 GRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   656 ----QQYQTEMEKLREKCEQE-----KETLLKDKEIIFQAHiEEMNEKTLEK---LDVKQTELESLSSELSEVLKARHKL 723
Cdd:TIGR02168  625 vlvvDDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGS-AKTNSSILERrreIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   724 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK---HLKEHQAH 798
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   799 VENLEADIKRSEGELQQASAKLDVFQSYQSATHE-----QTKAYEEQLAQLQQKLLDLETERIL--LTKQVAEVEAQKKD 871
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlRERLESLERRIAATERRLEDLEEQIeeLSEDIESLAAEIEE 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   872 VCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVyESKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKL 951
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLEL----RLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 578805993   952 SAKEDSihiLNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 992
Cdd:TIGR02168  939 DNLQER---LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 338-657 3.28e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.20  E-value: 3.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  338 ALQEQLDERLQELEKIKDLHM-AEKTKLITQLRDAKNLIEQLEqdkgmviaetkrqmhETLEMKEEEIAQLRSRIKQMTT 416
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELeAELEELEAELEELEAELEELE---------------AELAELEAELEELRLELEELEL 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  417 QGEELREQkEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIektsEEERISLQQELSRVKQEVVDVMKK--SS 494
Cdd:COG1196   282 ELEEAQAE-EYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEELEEELEELEEELEEAEEEleEA 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  495 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENK 574
Cdd:COG1196   357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  575 LRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVL 654
Cdd:COG1196   437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516


                  ...
gi 578805993  655 KQQ 657
Cdd:COG1196   517 AGL 519
PTZ00121 PTZ00121
MAEBL; Provisional
 405-1144 3.63e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.01  E-value: 3.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  405 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERiSLQQELSRVKQ 484
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  485 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREfqEQMKVALEKSQSEYLKisQEKEQQESLALEELELQK 564
Cdd:PTZ00121 1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  565 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvhlEAEKNKHNKEITVMVEKHKTElESLKHQQD 644
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEE 1313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  645 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 724
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  725 EELSVLKDQTDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQInqlelllkeRDKHLKEHQAHVENL 802
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEA---------KKKAEEAKKAEEAKK 1464

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  803 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV----EAQKKDVCTELDA 878
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  879 HKiQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 958
Cdd:PTZ00121 1545 KK-KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  959 HILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDA 1037
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1038 VSRLETNQKEQIESLTEVHRRElnDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1117
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAE--EENKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780

                         730       740
                  ....*....|....*....|....*..
gi 578805993 1118 KEEGVKQDTTLNELQEQLKQKSAHVNS 1144
Cdd:PTZ00121 1781 IEEELDEEDEKRRMEVDKKIKDIFDNF 1807
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1069-1864 3.76e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 3.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1069 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQK---------- 1138
Cdd:TIGR02168  203 KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELrlevseleee 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1139 ----SAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEK 1214
Cdd:TIGR02168  283 ieelQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1215 SNKSLEDKSLEFKKLSEE-----------------LAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRT 1277
Cdd:TIGR02168  363 LEAELEELESRLEELEEQletlrskvaqlelqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1278 TKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEK 1357
Cdd:TIGR02168  443 EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1358 ESCITQLKKE----------LSENINAVTLmkEELKEKKVEISSLSKQL--------------TDLNVQLQNSISLSEKE 1413
Cdd:TIGR02168  523 GVLSELISVDegyeaaieaaLGGRLQAVVV--ENLNAAKKAIAFLKQNElgrvtflpldsikgTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1414 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLsKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLElKSKE 1493
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGVLVVDDL-DNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILE-RRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1494 AYEKDEQINLLKEELDQQNKRFDCLKGE---MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1570
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKEleeLEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1571 YNQQKDIEHKELVQKLQHFQELGEEKdnrvKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1650
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEI----EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1651 S--ESAAKLAELKRKAEQKIAAIKKQlLSQMEEKEEQYKKGTESHL---SELNTKLQEREREVHILEEKLKSVES--SQS 1723
Cdd:TIGR02168  835 AteRRLEDLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLnerASLEEALALLRSELEELSEELRELESkrSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1724 ETLIVPRSAKNVAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEmrcQYQERLIKLEHA 1803
Cdd:TIGR02168  914 RRELEELREKLAQLELRLEGL----------EVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE---EARRRLKRLENK 980

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578805993  1804 EAKqhedqsmIGHLQ----EELEEKNKKYSLIVAQHVEKEGGKNNIQ---------AKQNLENVFDDVQKTLQE 1864
Cdd:TIGR02168  981 IKE-------LGPVNlaaiEEYEELKERYDFLTAQKEDLTEAKETLEeaieeidreARERFKDTFDQVNENFQR 1047
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 723-1046 5.04e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 5.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  723 LEEELSVLKDQTDKMK--QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 800
Cdd:COG1196   198 LERQLEPLERQAEKAEryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  801 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 880
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  881 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVekenmILQMREGQKKEIEILTQKLSAKEDSIHI 960
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAE 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  961 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1040
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512


                  ....*.
gi 578805993 1041 LETNQK 1046
Cdd:COG1196   513 ALLLAG 518
PTZ00121 PTZ00121
MAEBL; Provisional
 196-803 5.68e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.63  E-value: 5.68e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  196 QRLRRMERSLSSYRGKYSEELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKplpqlepQA 275
Cdd:PTZ00121 1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK-------AD 1281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  276 EVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKET---IQSHKEQCTLLTSEKEALQEQLDERLQELEK 352
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkkADAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  353 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmviAETKRQMHETLEMKEEEIAQLRSRIKQmttqGEELREQKEKSERAa 432
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKKKAEEDKKKADELKKAAAAKKK----ADEAKKKAEEKKKA- 1433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  433 fEELEKALSTAQKTEEARRKlkAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 512
Cdd:PTZ00121 1434 -DEAKKKAEEAKKADEAKKK--AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  513 EQELTKKLQTR----------EREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 582
Cdd:PTZ00121 1511 KADEAKKAEEAkkadeakkaeEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  583 ETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 662
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  663 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSvLKDQTDKMKQELE 742
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAK-KEAEEDKKKAEEA 1749

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578805993  743 AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQL-ELLLKERDKHLKEHQAHVENLE 803
Cdd:PTZ00121 1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEdEKRRMEVDKKIKDIFDNFANII 1811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1481-2106 6.39e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 6.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1481 KELQIQLELKSKEAYEKdeQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1560
Cdd:COG1196   216 RELKEELKELEAELLLL--KLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1561 IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN---RVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1637
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAEleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1638 KEEELKALEDRLESESAAKLAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKS 1717
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRAAAEL------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1718 VESSQSETLivprsaknvAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSshfemrcqyqeRL 1797
Cdd:COG1196   444 LEEAAEEEA---------ELEEEEEAL----------LELLAELLEEAALLEAALAELLEELAEAAA-----------RL 493

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1798 IKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENvfDDVQKTLQEKELTCQILEQKIK 1877
Cdd:COG1196   494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ--NIVVEDDEVAAAAIEYLKAAKA 571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1878 ELDSCLVRQKEVHRVEMEELTSKYEKLQA--LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1955
Cdd:COG1196   572 GRATFLPLDKIRARAALAAALARGAIGAAvdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1956 EREKQKLGKEIVRLQ-KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM 2034
Cdd:COG1196   652 EGEGGSAGGSLTGGSrRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578805993 2035 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEI----LDAREE--EMTAKVRDLQTQLEELQK 2106
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAIEEyeELEERYDFLSEQREDLEE 809
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1024-1909 6.39e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.16  E-value: 6.39e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1024 LEMAQANSAGISDAVSRLETN------QKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELK 1097
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlkslerQAEKAERYKELKAELRELELALLVLRLEELREELEELQE-ELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1098 QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1177
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1178 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQldicckktealleakTNELIN 1257
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL---------------NNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1258 ISSSktnaiLSRISHCQHRTTKVKEALLIKTctvseLEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLv 1337
Cdd:TIGR02168  405 LEAR-----LERLEDRRERLQQEIEELLKKL-----EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA- 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1338 teKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEElkekkveisslsKQLTDLNVQLQNSISLSEK-EAAI 1416
Cdd:TIGR02168  474 --EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ------------SGLSGILGVLSELISVDEGyEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1417 SSLrkqydeekceLLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYE 1496
Cdd:TIGR02168  540 EAA----------LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1497 KDEQINLLKEELDQQNKRFDCLKGEMEDDKSKmekkesnletelkSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKD 1576
Cdd:TIGR02168  610 FDPKLRKALSYLLGGVLVVDDLDNALELAKKL-------------RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1577 IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESaak 1656
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS--- 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1657 lAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETlivprsaknva 1736
Cdd:TIGR02168  754 -KELTELEAE------IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL----------- 815

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1737 ayteQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH 1816
Cdd:TIGR02168  816 ----NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1817 LQEELEEKNKKyslivaqhvEKEGGKNNIQAKQNLENvfddVQKTLQEKELTCQILEQKIKELdscLVRQKEVHRVEMEE 1896
Cdd:TIGR02168  892 LRSELEELSEE---------LRELESKRSELRRELEE----LREKLAQLELRLEGLEVRIDNL---QERLSEEYSLTLEE 955

                          890
                   ....*....|...
gi 578805993  1897 LTSKYEKLQALQQ 1909
Cdd:TIGR02168  956 AEALENKIEDDEE 968
PTZ00121 PTZ00121
MAEBL; Provisional
 1410-1878 6.94e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 6.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1410 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQiQLEL 1489
Cdd:PTZ00121 1286 AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1490 KSKEAYEKDEQINLLKEELD---QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARimeledhitqktieiESLNE 1566
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK---------------KKAEE 1429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1567 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQvysMKAELETKKKELEHVNLSVKSKEEELKALE 1646
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK---KKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1647 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1726
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1727 --IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1803
Cdd:PTZ00121 1587 kkAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578805993 1804 EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE 1878
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 337-953 7.25e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 7.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  337 EALQEQLDERLQELEKikdlhMAEKTklitqlRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTT 416
Cdd:COG1196   192 EDILGELERQLEPLER-----QAEKA------ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  417 QGEELREQKEKsERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS---EEERISLQQELSRVKQEVVDVmkKS 493
Cdd:COG1196   261 ELAELEAELEE-LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRrelEERLEELEEELAELEEELEEL--EE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  494 SEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEksqseylkisQEKEQQESLALEELELQKKAILTESEN 573
Cdd:COG1196   338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE----------LEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  574 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 653
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALE-EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  654 LKQQYQTEMEKlrekcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR-HKLEEELSVLKD 732
Cdd:COG1196   487 AEAAARLLLLL-----EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALqNIVVEDDEVAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  733 QTDKMKQELEAKMDEqknhhqQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 812
Cdd:COG1196   562 AIEYLKAAKAGRATF------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  813 LQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 892
Cdd:COG1196   636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578805993  893 QNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQM--REGQKKEIEILTQKLSA 953
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpdLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 388-1007 1.10e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  388 ETKRQMHETlemkEEEIAQLRSRIKQMTTQGEELREQKEKSERAAfeELEKALSTAQKTEEARRKLKAEMDEQIKTIEKT 467
Cdd:COG1196   176 EAERKLEAT----EENLERLEDILGELERQLEPLERQAEKAERYR--ELKEELKELEAELLLLKLRELEAELEELEAELE 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  468 SEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTkklQTREREFQEQMKVALEKSQSEyLKISQ 547
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR---LEQDIARLEERRRELEERLEE-LEEEL 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  548 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEitv 627
Cdd:COG1196   326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL--- 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  628 mvEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEiifQAHIEEMNEKTLEKLDVKQTELE 707
Cdd:COG1196   403 --EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL---EEEEEALLELLAELLEEAALLEA 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  708 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSII---KEHEVSIQ-RTEKALKDQINQLEL 783
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveAAYEAALEaALAAALQNIVVEDDE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  784 LLKERDKHLKEHQAH-VENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV 862
Cdd:COG1196   558 VAAAAIEYLKAAKAGrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  863 AEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK 942
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578805993  943 EIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLldqeAKLKKELEN 1007
Cdd:COG1196   718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL----ERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 331-629 1.37e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  331 LLTSEKEALQEQLDERLQELEKIkDLHMAEKTKLITQLRDAKNLIEQLEQDKGmviaETKRQMHETLEMKEEEIAQLRSR 410
Cdd:COG1196   236 ELEAELEELEAELEELEAELEEL-EAELAELEAELEELRLELEELELELEEAQ----AEEYELLAELARLEQDIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  411 IKQMTTQGEELREQKEKSERAAfEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 490
Cdd:COG1196   311 RRELEERLEELEEELAELEEEL-EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  491 KKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEylKISQEKEQQESLALEELELQKKAILTE 570
Cdd:COG1196   390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE--EEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 578805993  571 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMV 629
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 308-1100 1.38e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 1.38e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   308 VKRQENLLKRCKETIQSHKE--------QCTLLTSEKEALQEQLDERLQELEKikdlhmaektkLITQLRDAKNLIEQLE 379
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKElkaelrelELALLVLRLEELREELEELQEELKE-----------AEEELEELTAELQELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   380 QDkgmvIAETKRQMHEtlemKEEEIAQLRSRIKQMTTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEM 457
Cdd:TIGR02168  267 EK----LEELRLEVSE----LEEEIEELQKELYALANEISRLEQQKQilRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   458 DEQIKTIEKTSEEERISLQQELSRVKQEVVDvmkksSEEQIAKLQKLHEKelARKEQELTKKLQTREREFQEQMKVALEK 537
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEE-----LESRLEELEEQLET--LRSKVAQLELQIASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   538 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLavhleAE 617
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL-----AQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   618 KNKHNKEITVMVEKHKTELESLKHQQDALWTEK--LQVLKQQYQTEmeklrEKCEQEKETLL---------KDKEIIFQA 686
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSgiLGVLSELISVD-----EGYEAAIEAALggrlqavvvENLNAAKKA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   687 hIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQ----------------ELEAKMDEQKN 750
Cdd:TIGR02168  562 -IAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvdDLDNALELAKK 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   751 HHQQ----------------------QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHqahvENLEADIKR 808
Cdd:TIGR02168  641 LRPGyrivtldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL----EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   809 SEGELQQASAKLdvfqsyqSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQ 888
Cdd:TIGR02168  717 LRKELEELSRQI-------SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   889 QLEKQNSEMEQKVKSLtqvyeSKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETK 968
Cdd:TIGR02168  790 QIEQLKEELKALREAL-----DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   969 FKNQEKKMEKVK--QKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSagisdAVSRLETNQK 1046
Cdd:TIGR02168  865 EELIEELESELEalLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL-----RLEGLEVRID 939

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 578805993  1047 EQIESLTEVHRRELndvisiwekklnQQAEELQEIHEIQLQEKEQEVAELKQKI 1100
Cdd:TIGR02168  940 NLQERLSEEYSLTL------------EEAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1573-2134 1.61e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1573 QQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESE 1652
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1653 SAAK--LAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgtESHLSELNTKLQEREREVHILEEKLKSVESSQSETL--IV 1728
Cdd:COG1196   301 EQDIarLEERRRELEERLEELEEELAELEEELEEL-----EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEaeLA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1729 PRSAKNVAAYTEQEEADSQgcvQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQH 1808
Cdd:COG1196   376 EAEEELEELAEELLEALRA---AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1809 EDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKE 1888
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1889 VHRVEMEELTSkyekLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHndlefKLAGAEREKQKLGKEIVR 1968
Cdd:COG1196   533 EAAYEAALEAA----LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR-----AALAAALARGAIGAAVDL 603

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1969 LQKDLRMLRKEHQQELEILKKEYDQER--EEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEV 2046
Cdd:COG1196   604 VASDLREADARYYVLGDTLLGRTLVAArlEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE 683

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2047 EAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIM 2126
Cdd:COG1196   684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763


                  ....*...
gi 578805993 2127 ELQTQLAQ 2134
Cdd:COG1196   764 ELERELER 771
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 730-1524 3.92e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 3.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   730 LKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHE---VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 806
Cdd:TIGR02168  218 LKAELRELELALLVLRLEELREELEELQEELKEAEeelEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   807 KRSEGELQQASAKLDvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 886
Cdd:TIGR02168  298 SRLEQQKQILRERLA-------NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   887 MQQLEKQNSEMEQKVKSLTQVYEsKLEDGNKEQE----QTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 962
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVAQLEL-QIASLNNEIErleaRLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   963 EEYETKFKNQEKKMEKVKQKAKEMQETLkKKLLDQEAKLKKELENTALELSQKEK-QFNAKMLEMAQANSAGISDAVSRL 1041
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQAL-DAAERELAQLQARLDSLERLQENLEGfSEGVKALLKNQSGLSGILGVLSEL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1042 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE-------------ELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1108
Cdd:TIGR02168  529 ISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAflkqnelgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1109 EMNKEIT-----WLkeEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHleklEVDLNKSLKENTFLQEQLVELKML 1183
Cdd:TIGR02168  609 KFDPKLRkalsyLL--GGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPG----GVITGGSAKTNSSILERRREIEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1184 AEEDKR---KVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLdiccKKTEALLEAKTNELINISS 1260
Cdd:TIGR02168  683 EEKIEEleeKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE----AEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1261 SktnailsrishcQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEK 1340
Cdd:TIGR02168  759 L------------EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1341 EALQKEGGNQQQAASEkescITQLKKELSENINAVTLmkeelkekkvEISSLSKQLTDLNVQLQ-NSISLSEKEAAISSL 1419
Cdd:TIGR02168  827 ESLERRIAATERRLED----LEEQIEELSEDIESLAA----------EIEELEELIEELESELEaLLNERASLEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1420 RKQYDeekcELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKA---QSRFTQHQNTVKELQIQLELKSKEAYE 1496
Cdd:TIGR02168  893 RSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIdnlQERLSEEYSLTLEEAEALENKIEDDEE 968

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 578805993  1497 K-DEQINLLK--------------EELDQQNKRFDCLKGEMED 1524
Cdd:TIGR02168  969 EaRRRLKRLEnkikelgpvnlaaiEEYEELKERYDFLTAQKED 1011
PTZ00121 PTZ00121
MAEBL; Provisional
 336-1063 4.41e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.55  E-value: 4.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  336 KEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNL--IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 413
Cdd:PTZ00121 1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNE 1252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  414 MTTQGEELREQKEKSERAAF--------EELEKAlSTAQKTEEARrklKAEMDEQIKTIEKTSEEERislqqELSRVKQE 485
Cdd:PTZ00121 1253 EIRKFEEARMAHFARRQAAIkaeearkaDELKKA-EEKKKADEAK---KAEEKKKADEAKKKAEEAK-----KADEAKKK 1323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  486 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKlqtrEREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK 565
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD----EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  566 AiltESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKdlavhleAEKNKHNKEITVMVEKHKTELESLKHQQDA 645
Cdd:PTZ00121 1400 A---EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK-------AEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  646 LWTEKLQVlKQQYQTEMEKLREKCEQEKEtllKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 725
Cdd:PTZ00121 1470 KKADEAKK-KAEEAKKADEAKKKAEEAKK---KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  726 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKehQAHVENLEAD 805
Cdd:PTZ00121 1546 KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK--KAEEAKIKAE 1623

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  806 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV--AEVEAQKKDVCTELDAHKIQV 883
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAkkAEEDEKKAAEALKKEAEEAKK 1703

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  884 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEkenmiLQMREGQKKEIEILTQKLSAKEDSIHI--- 960
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE-----AKKDEEEKKKIAHLKKEEEKKAEEIRKeke 1778

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  961 ------LNEEYETKFKNQEKKMEKVKQKAKEMQE---------TLKKKLLDQEAKLKKELENTALELSQKEKQ--FNAKM 1023
Cdd:PTZ00121 1779 avieeeLDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlviNDSKEMEDSAIKEVADSKNMQLEEADAFEKhkFNKNN 1858

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|
gi 578805993 1024 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDV 1063
Cdd:PTZ00121 1859 ENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDI 1898
PTZ00121 PTZ00121
MAEBL; Provisional
 1411-2122 2.16e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.24  E-value: 2.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1411 EKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSK-------EKISALEQVDDWSNKFSEWKKKAQ-SRFTQHQNTVKE 1482
Cdd:PTZ00121 1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKaeeernnEEIRKFEEARMAHFARRQAAIKAEeARKADELKKAEE 1288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1483 LQIQLELKSKEAYEKDEQINLLKEE---LDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEdhitqKTI 1559
Cdd:PTZ00121 1289 KKKADEAKKAEEKKKADEAKKKAEEakkADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-----AAE 1363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1560 EIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEkiltlenqvysMKAELETKKKELEhvnlSVKSKE 1639
Cdd:PTZ00121 1364 EKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADE-----------LKKAAAAKKKADE----AKKKAE 1428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1640 EELKALEDRLESESAAKLAELKRKAEQKIAAikkqllsqmeekEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE 1719
Cdd:PTZ00121 1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKA------------EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1720 SSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQrvgQEKEETVSSHFEMRCQYQERlik 1799
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE---LKKAEELKKAEEKKKAEEAK--- 1570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1800 lehaeaKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVF--DDVQKTLQEKELTCQILEQKIK 1877
Cdd:PTZ00121 1571 ------KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIkaEELKKAEEEKKKVEQLKKKEAE 1644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1878 EldsclVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQpkllsnmeaqhndlEFKLAGAER 1957
Cdd:PTZ00121 1645 E-----KKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK--------------EAEEAKKAE 1705

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1958 EKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEydqEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK 2037
Cdd:PTZ00121 1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE---AEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2038 ETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2117
Cdd:PTZ00121 1783 EELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGE 1862


                  ....*
gi 578805993 2118 PGNDN 2122
Cdd:PTZ00121 1863 DGNKE 1867
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 760-1507 2.96e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 2.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   760 IKEHEVSIQRTEK---ALKDQINQLELLLKERDKHLKEHQAHVENLEADIKR-SEGELQQASAKLDVFQSYQSATHEQTK 835
Cdd:TIGR02169  232 KEALERQKEAIERqlaSLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIA 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   836 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL------TQVYE 909
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdeLKDYR 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   910 SKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQkAKEMQET 989
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSE----ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ-LAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   990 LKKKLLDQEA---KLKKELENTALELSQKEKQ---------FNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR 1057
Cdd:TIGR02169  467 YEQELYDLKEeydRVEKELSKLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAG 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1058 RELNDVISIWEKKLNQQAEELQE----------IHEIQLQEKEQEVAELKQKIL----LFGCEKEEMNKEITWLKEEGVK 1123
Cdd:TIGR02169  547 NRLNNVVVEDDAVAKEAIELLKRrkagratflpLNKMRDERRDLSILSEDGVIGfavdLVEFDPKYEPAFKYVFGDTLVV 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1124 QDTT----------LNELQEQLKQKSAHV-------NSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1186
Cdd:TIGR02169  627 EDIEaarrlmgkyrMVTLEGELFEKSGAMtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1187 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELA---IQLDICCKKTEALLEAKTNELINISSSKT 1263
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvkSELKELEARIEELEEDLHKLEEALNDLEA 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1264 NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEAL 1343
Cdd:TIGR02169  787 RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1344 QKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNsisLSEKEAAISSLRKQY 1423
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA---LEEELSEIEDPKGED 943

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1424 DEEKCELLDqVQDLSFKVDTLsKEKISALEQVDdwsNKFSEWKKKAQSRFtqhqNTVKELQIQLELKSKEAYEKDEQINL 1503
Cdd:TIGR02169  944 EEIPEEELS-LEDVQAELQRV-EEEIRALEPVN---MLAIQEYEEVLKRL----DELKEKRAKLEEERKAILERIEEYEK 1014


                   ....
gi 578805993  1504 LKEE 1507
Cdd:TIGR02169 1015 KKRE 1018
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1464-2103 3.72e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 3.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1464 EWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKgEMEDDKSKMEKKESNLETELKSQ 1543
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE-ELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1544 TARIMELEDHITQKTIEIESLNEVLKNYNQQKdiEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1623
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELK--EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1624 KKKELEHVNLSVKSKEEELKALEDRLES-ESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQ 1702
Cdd:PRK03918  336 KEERLEELKKKLKELEKRLEELEERHELyEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIG 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1703 EREREVHILEEKLKSVESSQSETLIVPRSaknvaaYTEQEEADsqgcVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEEt 1782
Cdd:PRK03918  416 ELKKEIKELKKAIEELKKAKGKCPVCGRE------LTEEHRKE----LLEEYTAELKRIEKELKEIEEKERKLRKELRE- 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1783 vsshFEMRCQYQERLIKL-EHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGG----KNNIQAKQNLENVFDD 1857
Cdd:PRK03918  485 ----LEKVLKKESELIKLkELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEikslKKELEKLEELKKKLAE 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1858 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLqalqqmdgrnkptelleenteekskshlvqpkl 1937
Cdd:PRK03918  561 LEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL--------------------------------- 607

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1938 lSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEhqqeLEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 2017
Cdd:PRK03918  608 -KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE----LEELEKKYSEEEYEELREEYLELSRELAGLRAEL 682

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2018 mrefntqlaqkeqelemtiketinkaqeveaELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE--EEMTAKVR 2095
Cdd:PRK03918  683 -------------------------------EELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALErvEELREKVK 731


                  ....*...
gi 578805993 2096 DLQTQLEE 2103
Cdd:PRK03918  732 KYKALLKE 739
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 335-1202 3.86e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 3.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   335 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETkrqmheTLEMKEEEIAQLRSRIKQM 414
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY------LLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   415 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 494
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   495 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS--QSEYLKISQEKEQQESLALEELELQKKAILTESE 572
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   573 NKLRDLQQEAETYRTRILELESSLEKSLQENKnqskdLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 652
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEE-----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   653 VLKQQYQTEMEKLREkcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 732
Cdd:pfam02463  480 VKLQEQLELLLSRQK--LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   733 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 812
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   813 LQQASAKLDVFQSYQSATHEQTkayEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 892
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   893 QNSEMEQKVKSLTQVYESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 971
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKInEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   972 QEKKMEKVKQKAKEmqetlKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1051
Cdd:pfam02463  795 KLKAQEEELRALEE-----ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1052 LTEVHRRELNDVISIWEKKLNQQAEELQEIHE-IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1130
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKElEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578805993  1131 LQEQLKQKSAHVNSLAQDEtklKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1202
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLA---KEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1467-1724 6.75e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 6.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1467 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTAR 1546
Cdd:COG1196   249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE----LARLEQDIARLEERRRELEERLEELEEE 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1547 IMELEDHITQKTIEIESLNEVLknynQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK 1626
Cdd:COG1196   325 LAELEEELEELEEELEELEEEL----EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1627 ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER 1706
Cdd:COG1196   401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                         250
                  ....*....|....*...
gi 578805993 1707 EVHILEEKLKSVESSQSE 1724
Cdd:COG1196   481 ELLEELAEAAARLLLLLE 498
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 875-1703 7.82e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.82e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   875 ELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYEsKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK 954
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLE-RLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   955 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQAnSAGI 1034
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA-EERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1035 SDAVSRLEtNQKEQIESLTE------VHRRELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQKILLFGCEKE 1108
Cdd:TIGR02169  325 AKLEAEID-KLLAEIEELEReieeerKRRDKLTEEYAELKEELEDLRAELEEV-DKEFAETRDELKDYREKLEKLKREIN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1109 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLnkslkentflqEQLVELKMLAEEDK 1188
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL-----------EQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1189 RKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAI-- 1266
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLnn 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1267 ----------------------------LSRISHCQHRTTKVKEALLI----------------------KTCTVSELEA 1296
Cdd:TIGR02169  552 vvveddavakeaiellkrrkagratflpLNKMRDERRDLSILSEDGVIgfavdlvefdpkyepafkyvfgDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1297 ------QLRQLTEEQNTL----------NISFQQATHQLEEKEnQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESC 1360
Cdd:TIGR02169  632 arrlmgKYRMVTLEGELFeksgamtggsRAPRGGILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1361 ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS--------LSEKEAAISSLRKQ----YDEEKC 1428
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSelkelearIEELEEDLHKLEEAlndlEARLSH 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1429 ELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEEL 1508
Cdd:TIGR02169  791 SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE----IQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1509 DQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiehkelvqklqh 1588
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS------------ 934

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1589 fqELGEEKDNRVKEAEEkILTLEnQVYSMKAELETKKKELEHVNlsvkskeeeLKALEDRleSESAAKLAELKRKaEQKI 1668
Cdd:TIGR02169  935 --EIEDPKGEDEEIPEE-ELSLE-DVQAELQRVEEEIRALEPVN---------MLAIQEY--EEVLKRLDELKEK-RAKL 998

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 578805993  1669 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1703
Cdd:TIGR02169  999 EEERKAILERIEEYEKKKREVFMEAFEAINENFNE 1033
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 319-638 8.16e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 60.91  E-value: 8.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   319 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 394
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   395 ETLEMKEEEIAQLRSRIKQMttqgEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKtIEKTSEEERis 474
Cdd:pfam17380  361 ELERIRQEEIAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQ-IRAEQEEAR-- 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   475 lQQELSRVKQEVVDVMKKSSEEQIAK---LQKLHEKELARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKE 550
Cdd:pfam17380  434 -QREVRRLEEERAREMERVRLEEQERqqqVERLRQQEEERKRKKLELEKEKRDRkRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   551 QQESLALEELELQKKAILTESEnklrdlQQEAETYRTRILELESslEKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMV 629
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEER------RREAEEERRKQQEMEE--RRRIQEQMRKATEERSRLEAmEREREMMRQIVES 584


                   ....*....
gi 578805993   630 EKHKTELES 638
Cdd:pfam17380  585 EKARAEYEA 593
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 697-1370 1.70e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 1.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   697 EKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQvdSIIKEHEVSIQRTEKALKD 776
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLER 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   777 QINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 856
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   857 LLTKQVAEVEAQKKD-------------------VCTELDAHKIQVQDLMQQLEK---QNSEMEQKVKSLTQVYESKLE- 913
Cdd:TIGR02168  397 SLNNEIERLEARLERledrrerlqqeieellkklEEAELKELQAELEELEEELEElqeELERLEEALEELREELEEAEQa 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   914 -DGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKfKNQEKKMEKV------------K 980
Cdd:TIGR02168  477 lDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAAlggrlqavvvenL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   981 QKAKEMQETLKKKLLDQEAKL------KKELENTALELSQKEKQFNAKMLEMAQANSAgISDAVS------RLETNQKEQ 1048
Cdd:TIGR02168  556 NAAKKAIAFLKQNELGRVTFLpldsikGTEIQGNDREILKNIEGFLGVAKDLVKFDPK-LRKALSyllggvLVVDDLDNA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1049 IESLTEVHRRE----LNDVISIWEKKLNQQAEElqeiHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEgvkq 1124
Cdd:TIGR02168  635 LELAKKLRPGYrivtLDGDLVRPGGVITGGSAK----TNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE---- 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1125 dttLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEE 1204
Cdd:TIGR02168  707 ---LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1205 FQSLKSSHEKSNKSLEDKSLEFKKLSEELaiqldicckktealleAKTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1284
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAEL----------------TLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1285 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQL 1364
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927


                   ....*.
gi 578805993  1365 KKELSE 1370
Cdd:TIGR02168  928 ELRLEG 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 671-1208 2.48e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  671 QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQtelESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKmDEQKN 750
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAEL---EELEAELEELEAELAELEAELEELRLELEELELELEEA-QAEEY 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  751 HHQQQVDSIIKEHEVSIQRtEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAT 830
Cdd:COG1196   292 ELLAELARLEQDIARLEER-RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  831 HEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES 910
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  911 KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEIltQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKE----- 985
Cdd:COG1196   451 EAELEEEEEALLELLAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavav 528

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  986 ------------------------MQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGI----SDA 1037
Cdd:COG1196   529 ligveaayeaaleaalaaalqnivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvaSDL 608

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1038 VSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1117
Cdd:COG1196   609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1118 KEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSK 1197
Cdd:COG1196   689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                         570
                  ....*....|.
gi 578805993 1198 LKTTDEEFQSL 1208
Cdd:COG1196   769 LERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 307-700 4.13e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 4.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   307 RVKRQENLLKRCKEtIQSHKEQCTLLTSEKEALQEQLDE---RLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKG 383
Cdd:TIGR02168  665 SAKTNSSILERRRE-IEELEEKIEELEEKIAELEKALAElrkELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   384 MViAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSEraafEELEKALSTAQKTEEARRKLKAEM-DEQIK 462
Cdd:TIGR02168  744 QL-EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE----AQIEQLKEELKALREALDELRAELtLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   463 TIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkelarkeqeltkKLQTREREFQEQMKVALEKSQSEY 542
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE------------ELEELIEELESELEALLNERASLE 886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   543 LKISQEKEQQESLALEELELQKKAilTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN 622
Cdd:TIGR02168  887 EALALLRSELEELSEELRELESKR--SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE 964

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578805993   623 KEItvmvEKHKTELESLKHQQDALWTEKLQVLkQQYQTEMEKLREKcEQEKETLLKDKEIIFQAhIEEMNEKTLEKLD 700
Cdd:TIGR02168  965 DDE----EEARRRLKRLENKIKELGPVNLAAI-EEYEELKERYDFL-TAQKEDLTEAKETLEEA-IEEIDREARERFK 1035
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2192-2235 5.48e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.48e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 578805993   2192 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2235
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 388-1146 9.03e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 9.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   388 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERaaFEELEKALSTAQKTEEARRKLKAEmdEQIKTIEKt 467
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYELLKEKEALE--RQKEAIER- 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   468 seeERISLQQELSRVKQEVVDVMKKSseEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQmkVALEKSQSEYLKISQ 547
Cdd:TIGR02169  245 ---QLASLEEELEKLTEEISELEKRL--EEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE--IASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   548 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKeitv 627
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK---- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   628 mVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME---KLREKCEQEKETLLKDKEIifqAHIEEMNEKTLEKLDVKQT 704
Cdd:TIGR02169  394 -LEKLKREINELKRELDRLQEELQRLSEELADLNAAiagIEAKINELEEEKEDKALEI---KKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   705 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ------QVDSIIKEHEVSIQRTEKALKDQI 778
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASiqgvhgTVAQLGSVGERYATAIEVAAGNRL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   779 NQL----ELLLKERDKHLKEHQA-----------HVENLEADIKRSEGELQQASAKLDVFQSYQSATH------------ 831
Cdd:TIGR02169  550 NNVvvedDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKyvfgdtlvvedi 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   832 EQTKAYEEQLAQLQQKLLDLE----------TERILLTKQVAEvEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKv 901
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEksgamtggsrAPRGGILFSRSE-PAELQRLRERLEGLKRELSSLQSELRRIENRLDEL- 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   902 KSLTQVYESKLEDGNKEQEQtkqilvekenmILQMREGQKKEIEILTQKLSAKEDSIhilneeyetkfKNQEKKMEKVKQ 981
Cdd:TIGR02169  708 SQELSDASRKIGEIEKEIEQ-----------LEQEEEKLKERLEELEEDLSSLEQEI-----------ENVKSELKELEA 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   982 KAKEMQETLKKkLLDQEAKLKKELENTALELSQKEKQfnaKMLEMAQANSAGISDAVSRLetNQKEQIESLTEVHRRELN 1061
Cdd:TIGR02169  766 RIEELEEDLHK-LEEALNDLEARLSHSRIPEIQAELS---KLEEEVSRIEARLREIEQKL--NRLTLEKEYLEKEIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1062 DVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAH 1141
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENL-NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918


                   ....*
gi 578805993  1142 VNSLA 1146
Cdd:TIGR02169  919 LSELK 923
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1942-2160 9.11e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 9.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1942 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRML-----RKEHQQELEILKKEYDQEREEKIKQEQEDLElKHNSTLKQ 2016
Cdd:COG1196   259 EAELAELEAELEELRLELEELELELEEAQAEEYELlaelaRLEQDIARLEERRRELEERLEELEEELAELE-EELEELEE 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2017 LMREFNTQLAQKEQELEMTIKETINKAQEVEA---------ELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE 2087
Cdd:COG1196   338 ELEELEEELEEAEEELEEAEAELAEAEEALLEaeaelaeaeEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE 417

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578805993 2088 EEMTAKVRDLQTQLEELQKKYQQKLEQEEnpgnDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRL 2160
Cdd:COG1196   418 RLEEELEELEEALAELEEEEEEEEEALEE----AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1280-2165 1.54e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 1.54e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1280 VKEALLIKTCTVSELEAQLRQLTEEQNTLnISFQQATHQLEEKENQIKSmkADIESLVTEKEALQKEggnqqqaASEKES 1359
Cdd:TIGR02169  182 VEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYELL--KEKEALERQKEAIERQ-------LASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1360 CITQLKKELSENinavtlmKEELKEKKVEISSLSKQLTDLNVQLQNSIS--LSEKEAAISSLRKQYDEEKcellDQVQDL 1437
Cdd:TIGR02169  252 ELEKLTEEISEL-------EKRLEEIEQLLEELNKKIKDLGEEEQLRVKekIGELEAEIASLERSIAEKE----RELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1438 SFKVDTLSKEKISALEQVDDWSNKFSEWKKkaqsRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC 1517
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERK----RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1518 LKGEMEDdkskMEKKESNLETELKSQTARIMELEdhitqktieieslnevlknyNQQKDIEhkelvQKLQHFQELGEEKD 1597
Cdd:TIGR02169  397 LKREINE----LKRELDRLQEELQRLSEELADLN--------------------AAIAGIE-----AKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1598 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLeseSAAKLAELKRKAEQKIAAIKKQ--- 1674
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA---RASEERVRGGRAVEEVLKASIQgvh 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1675 -LLSQMEEKEEQYKKGTESHLS-ELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSaknvaayteqeeADSQGCVQK 1752
Cdd:TIGR02169  525 gTVAQLGSVGERYATAIEVAAGnRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKM------------RDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1753 TYEEKISVLQRNLTEKEKLLQRVgqekeetvsshfeMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNkkySLIV 1832
Cdd:TIGR02169  593 LSEDGVIGFAVDLVEFDPKYEPA-------------FKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKS---GAMT 656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1833 AQHVEKEGGKNNiqakqnlenvfddvQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSkyeKLQALQQMDG 1912
Cdd:TIGR02169  657 GGSRAPRGGILF--------------SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ---ELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1913 RNKPTELLEENTEEKSKshlvqpKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKehqqELEILKKEYD 1992
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLK------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE----ALNDLEARLS 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1993 QEREEKIKQEQEDLELKHNSTLKQLmREFNTQLAQKEQELEMTIKETINKAQEVEA--ELLESHQEETNQLLKKIAEKDD 2070
Cdd:TIGR02169  790 HSRIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDlkEQIKSIEKEIENLNGKKEELEE 868

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2071 DLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKKYQQ-KLEQEENPGNDNVTIMELQTQLAQKTTlISDSKLKEQEF 2149
Cdd:TIGR02169  869 ELEELEAALRD-LESRLGDLKKERDELEAQLRELERKIEElEAQIEKKRKRLSELKAKLEALEEELSE-IEDPKGEDEEI 946

                          890
                   ....*....|....*.
gi 578805993  2150 REQIHNLEDRLKKYEK 2165
Cdd:TIGR02169  947 PEEELSLEDVQAELQR 962
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
301-538 1.81e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  301 LETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQ------------EQLDERLQELEKikDLHMAEKT-----K 363
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeidvASAEREIAELEA--ELERLDASsddlaA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  364 LITQLRDAKNLIEQLEQDKGMVIAETKRqmhetlemKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTA 443
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGR--------LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  444 QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM--KKSSEEQIAKLQKLHEKELARKEQELTKKLQ 521
Cdd:COG4913   762 AVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDadLESLPEYLALLDRLEEDGLPEYEERFKELLN 841

                         250
                  ....*....|....*..
gi 578805993  522 TREREFQEQMKVALEKS 538
Cdd:COG4913   842 ENSIEFVADLLSKLRRA 858
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 433-1237 4.61e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 4.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   433 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 512
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   513 EQELTKKLQTREREF----------QEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 582
Cdd:pfam02463  239 IDLLQELLRDEQEEIesskqeiekeEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   583 ETYRTRILELESSLEKSLQENKNQSKDLavhLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 662
Cdd:pfam02463  319 SEKEKKKAEKELKKEKEEIEELEKELKE---LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   663 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELE 742
Cdd:pfam02463  396 ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   743 AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKrsegelqQASAKLDV 822
Cdd:pfam02463  476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN-------YKVAISTA 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   823 FQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 901
Cdd:pfam02463  549 VIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKlKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   902 KSLTqvYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQ 981
Cdd:pfam02463  629 LKDT--ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   982 KAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQ-FNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRREL 1060
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQkIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1061 NDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCE---KEEMNKEITWLKEEGVKQDTTLNELQEQLKQ 1137
Cdd:pfam02463  787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEeelEELALELKEEQKLEKLAEEELERLEEEITKE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1138 KSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTfLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1217
Cdd:pfam02463  867 ELLQELLLKEEELEEQKLKDELESKEEKEKEEKK-ELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEA 945

                          810       820
                   ....*....|....*....|
gi 578805993  1218 SLEDKSLEFKKLSEELAIQL 1237
Cdd:pfam02463  946 DEKEKEENNKEEEEERNKRL 965
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1508-2033 5.58e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.05  E-value: 5.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1508 LDQQNKRFDCLKGEMEDDKSK-MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiEHKELVQKL 1586
Cdd:PRK02224  182 LSDQRGSLDQLKAQIEEKEEKdLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE-ELETLEAEI 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1587 QHFQEL-------GEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsESAAKLAE 1659
Cdd:PRK02224  261 EDLRETiaetereREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE-ECRVAAQA 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1660 LKRKAEQKIAAIKkQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETlivPRSAKNVAAYT 1739
Cdd:PRK02224  340 HNEEAESLREDAD-DLEERAEELREEAAE-LESELEEAREAVEDRREEIEELEEEIEELRERFGDA---PVDLGNAEDFL 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1740 E--QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQ-----RVGQEKEEtvSSHFEMRCQYQERLIKLEhAEAKQHEDQs 1812
Cdd:PRK02224  415 EelREERDELREREAELEATLRTARERVEEAEALLEagkcpECGQPVEG--SPHVETIEEDRERVEELE-AELEDLEEE- 490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1813 mighlQEELEEKNKKYSLIVAQHVEKEGGKNNiqaKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRV 1892
Cdd:PRK02224  491 -----VEEVEERLERAEDLVEAEDRIERLEER---REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAE 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1893 EMEELTSKYEKLQALQQMDGRNKPTELleenteekskshlvqpkllsnmeaQHNDLEFKLAGAErekqKLGKEIVRLQKd 1972
Cdd:PRK02224  563 AEEEAEEAREEVAELNSKLAELKERIE------------------------SLERIRTLLAAIA----DAEDEIERLRE- 613

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578805993 1973 lrmlRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELE 2033
Cdd:PRK02224  614 ----KREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLD 670
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 860-1716 1.10e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.21  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   860 KQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMilqmreg 939
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD------- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   940 QKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQF 1019
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1020 NAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELN--DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELK 1097
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQleEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1098 QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1177
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1178 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSnksledKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELIN 1257
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS------AHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1258 ISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLV 1337
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1338 TEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAIS 1417
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1418 SLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEK 1497
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1498 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELksqtariMELEDHITQKTIEIESLNEVLKNYNQQKDI 1577
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE-------QKLEKLAEEELERLEEEITKEELLQELLLK 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1578 EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1657
Cdd:pfam02463  876 EEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNK 955

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578805993  1658 AELKRKAEQKIAAIKK------QLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLK 1716
Cdd:pfam02463  956 EEEEERNKRLLLAKEElgkvnlMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1530-1874 1.33e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1530 EKKESNLEtELKSQTARIMELEDHITQKTIEIESLNEvlknyNQQKDIEHKELVQKLQHFQelGEEKDNRVKEAEEKILT 1609
Cdd:TIGR02169  170 RKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRR-----EREKAERYQALLKEKREYE--GYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1610 LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE---------QKIAAIKKQLLSQME 1680
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGeleaeiaslERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1681 EKEEQYKKGTESHLSELnTKLQEREREVHILEEKLKSVESSQSETLIVPRSAknvaayTEQEEADSQGCVQKT--YEEKI 1758
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEI-EELEREIEEERKRRDKLTEEYAELKEELEDLRAE------LEEVDKEFAETRDELkdYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1759 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRcqyqerlIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1838
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLN-------AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 578805993  1839 EGGKNNIQAKQN-LENVFDDVQKTLQEKELTCQILEQ 1874
Cdd:TIGR02169  468 EQELYDLKEEYDrVEKELSKLQRELAEAEAQARASEE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1151-1720 1.60e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.79  E-value: 1.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1151 KLKAHLEKLEVDLnkSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1230
Cdd:COG1196   217 ELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1231 EELAiqldicckKTEALLEAKTNELINISSSKTNAILSRISHCQHRttkvkealliktctvSELEAQLRQLTEEQNTLNI 1310
Cdd:COG1196   295 AELA--------RLEQDIARLEERRRELEERLEELEEELAELEEEL---------------EELEEELEELEEELEEAEE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1311 SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1390
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1391 SLSKQLTDLNVQLQNSIS----LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK 1466
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1467 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTAR 1546
Cdd:COG1196   512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAA 591

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1547 IMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKlqhfQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK 1626
Cdd:COG1196   592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA----RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1627 ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER 1706
Cdd:COG1196   668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                         570
                  ....*....|....
gi 578805993 1707 EVHILEEKLKSVES 1720
Cdd:COG1196   748 LEEEALEELPEPPD 761
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1356-2172 3.58e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 3.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1356 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQ 1435
Cdd:pfam02463  206 AKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1436 DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE--LKSKEAYEKDEQINLLKEELDQQNK 1513
Cdd:pfam02463  286 EELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEelEKELKELEIKREAEEEEEEELEKLQ 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1514 RFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEI----ESLNEVLKNYNQQKDIEHKELVQKLQHF 1589
Cdd:pfam02463  366 EKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELarqlEDLLKEEKKEELEILEEEEESIELKQGK 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1590 QELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIA 1669
Cdd:pfam02463  446 LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRII 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1670 AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGC 1749
Cdd:pfam02463  526 SAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1750 VQKTYEE-KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKY 1828
Cdd:pfam02463  606 AQLDKATlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1829 SLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT-CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQAL 1907
Cdd:pfam02463  686 ESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADrVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1908 QQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL 1987
Cdd:pfam02463  766 KSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1988 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2067
Cdd:pfam02463  846 QKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2068 KDDDLKrtaKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQ 2147
Cdd:pfam02463  926 EAEILL---KYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEE 1002

                          810       820
                   ....*....|....*....|....*
gi 578805993  2148 EFREQIHNLEDRLKKYEKNVYATTV 2172
Cdd:pfam02463 1003 EKKKLIRAIIEETCQRLKEFLELFV 1027
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1422-2165 3.99e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 3.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1422 QYDEEK---CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK----KKAQSRFTQHQNTVKELQIQLELKSKEA 1494
Cdd:TIGR02169  167 EFDRKKekaLEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQallkEKREYEGYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1495 YEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESN----LETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1570
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAEIASLERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1571 YNQQ---KDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLS---VKSKEEELKA 1644
Cdd:TIGR02169  327 LEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKlekLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1645 LEDRLESES---AAKLAELKRKAEQKIAAIKkQLLSQMEEKEEQYKKGT-------------ESHLSELNTKLQEREREV 1708
Cdd:TIGR02169  407 ELDRLQEELqrlSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEwkleqlaadlskyEQELYDLKEEYDRVEKEL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1709 HILEEKLKSVESSQSetLIVPRSAKNVAAyTEQEEADSQGcVQKTYEEKISVLQRNLTEKE----KLLQRVGQEKEETVS 1784
Cdd:TIGR02169  486 SKLQRELAEAEAQAR--ASEERVRGGRAV-EEVLKASIQG-VHGTVAQLGSVGERYATAIEvaagNRLNNVVVEDDAVAK 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1785 SHFEMRCQYQ-ERLIKLEHAEAKQHEDQSMIGHLQE------ELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1857
Cdd:TIGR02169  562 EAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGvigfavDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRM 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1858 VQktlqekeLTCQILEQK--IKELDSCLVRQKEVHRVEMEELTSKYEKLQALQqmdgrnkptelleenteekskshlvqp 1935
Cdd:TIGR02169  642 VT-------LEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLK--------------------------- 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1936 KLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKkeydqEREEKIKQEQEDLElkhnsTLK 2015
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE-----ELEEDLSSLEQEIE-----NVK 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2016 QLMREFNTQLAQKEQELEmtiketinkaqEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVR 2095
Cdd:TIGR02169  758 SELKELEARIEELEEDLH-----------KLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL 826

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2096 DLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2165
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 298-989 4.12e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 4.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   298 VKTLETLQQRVKR----QENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKN 373
Cdd:TIGR02169  271 EQLLEELNKKIKDlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERK 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   374 LIEQLeQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 453
Cdd:TIGR02169  351 RRDKL-TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   454 K----------AEMDEQIKTIEKtSEEERISLQQELSRVKQEVVDvmKKSSEEQIAKLQKLHEKELARKEQELtKKLQTR 523
Cdd:TIGR02169  430 AgieakineleEEKEDKALEIKK-QEWKLEQLAADLSKYEQELYD--LKEEYDRVEKELSKLQRELAEAEAQA-RASEER 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   524 EREFQEQMKVALEKSQSEYLKISQ---EKEQQESLALEELELQKKAILTESE-------NKLRDLQQEAETY--RTRILE 591
Cdd:TIGR02169  506 VRGGRAVEEVLKASIQGVHGTVAQlgsVGERYATAIEVAAGNRLNNVVVEDDavakeaiELLKRRKAGRATFlpLNKMRD 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   592 LESSLEKSLqenKNQSKDLAVHLEAEKNKHNKEI------TVMVEkhktELESLKHQQD--------------------- 644
Cdd:TIGR02169  586 ERRDLSILS---EDGVIGFAVDLVEFDPKYEPAFkyvfgdTLVVE----DIEAARRLMGkyrmvtlegelfeksgamtgg 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   645 ALWTEKLQVLKQQYQTEMEKLREkceqEKETLLKDKEIIFQ--AHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHK 722
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRE----RLEGLKRELSSLQSelRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   723 LEEELSVLKDQTDKMKQELEAKMDEQKnhhqqQVDSIIKEHEVSIQRTEKALKD--------QINQLELLLKERDKHLKE 794
Cdd:TIGR02169  735 LKERLEELEEDLSSLEQEIENVKSELK-----ELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAELSKLEEEVSR 809

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   795 HQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCT 874
Cdd:TIGR02169  810 IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK 889

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   875 ELDAHKIQVQDLMQQLEKQNSEMEQKVK--SLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQkKEIEILTQKLS 952
Cdd:TIGR02169  890 ERDELEAQLRELERKIEELEAQIEKKRKrlSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQ-AELQRVEEEIR 968

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 578805993   953 AKEDSIHILNEEYET---KFKNQEKKMEKVKQKAKEMQET 989
Cdd:TIGR02169  969 ALEPVNMLAIQEYEEvlkRLDELKEKRAKLEEERKAILER 1008
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 759-1225 4.54e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 4.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   759 IIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 838
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLN 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   839 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDA---------HKIQVQDLMQ----QLEKQNSEMEQKVKSLT 905
Cdd:TIGR04523  159 NKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKlelllsnlkKKIQKNKSLEsqisELKKQNNQLKDNIEKKQ 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   906 QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKkEIEILTQKLSAKEDSIHILNEEYE---------------TKFK 970
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK-ELEQNNKKIKELEKQLNQLKSEISdlnnqkeqdwnkelkSELK 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   971 NQEKKMEKVKQKAKEMQETLKKkLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISdavsrletnQKEQIE 1050
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQ-LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS---------YKQEIK 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1051 SLtEVHRRELNDVISIwEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1130
Cdd:TIGR04523  388 NL-ESQINDLESKIQN-QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRES 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1131 LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1210
Cdd:TIGR04523  466 LETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545

                          490
                   ....*....|....*
gi 578805993  1211 SHEKSNKSLEDKSLE 1225
Cdd:TIGR04523  546 ELNKDDFELKKENLE 560
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 888-1720 5.69e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.90  E-value: 5.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   888 QQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET 967
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   968 KfkNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE 1047
Cdd:pfam02463  249 E--QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1048 QIESLTEVHRRELndvISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTT 1127
Cdd:pfam02463  327 EKELKKEKEEIEE---LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1128 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1207
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1208 LKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIK 1287
Cdd:pfam02463  484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1288 TCTVSELEAQLRQLTEEQnTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1367
Cdd:pfam02463  564 QKLVRALTELPLGARKLR-LLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1368 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE 1447
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1448 KISALEQVDDWSNKFSEWKKKAQSRFTQhqntvKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS 1527
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEE-----EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLK 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1528 KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1607
Cdd:pfam02463  798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEE 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1608 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ-----KIAAIKKQLLSQMEEK 1682
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEpeellLEEADEKEKEENNKEE 957

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 578805993  1683 EEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVES 1720
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDEL 995
PTZ00121 PTZ00121
MAEBL; Provisional
 736-1247 6.35e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.68  E-value: 6.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  736 KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 815
Cdd:PTZ00121 1230 KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKK 1309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  816 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNS 895
Cdd:PTZ00121 1310 KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE----KAEAAEKKKEEAKKKADAAKK 1385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  896 EMEQKVKSlTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 975
Cdd:PTZ00121 1386 KAEEKKKA-DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  976 MEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK-EQIESLTE 1054
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKaDEAKKAEE 1544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1055 VHRRElndviSIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQ 1134
Cdd:PTZ00121 1545 KKKAD-----ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1135 LK----QKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQlveLKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1210
Cdd:PTZ00121 1620 IKaeelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE---EAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 578805993 1211 SHEKSNKS--LEDKSLEFKKLSEELAIQLDICCKKTEAL 1247
Cdd:PTZ00121 1697 EAEEAKKAeeLKKKEAEEKKKAEELKKAEEENKIKAEEA 1735
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 319-1235 7.89e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.59  E-value: 7.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   319 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLhmaEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 398
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKAL---ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQIT 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   399 MKEEEIAQLRSRIKQMTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEEARRKLKAEM-----------DEQIKTIE 465
Cdd:TIGR00606  228 SKEAQLESSREIVKSYENELDPLKNRLKEIEhnLSKIMKLDNEIKALKSRKKQMEKDNSELelkmekvfqgtDEQLNDLY 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   466 -------KTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA------KLQKLHEKELARKEQELTKKLQTREREFQEQMK 532
Cdd:TIGR00606  308 hnhqrtvREKERELVDCQRELEKLNKERRLLNQEKTELLVEqgrlqlQADRHQEHIRARDSLIQSLATRLELDGFERGPF 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   533 VALEKSQSEYLKIS-QEKEQQESLALEELELQKKAILTESENKLRDlqqeAETYRTRILELESSLeksLQENKNQSKDLA 611
Cdd:TIGR00606  388 SERQIKNFHTLVIErQEDEAKTAAQLCADLQSKERLKQEQADEIRD----EKKGLGRTIELKKEI---LEKKQEELKFVI 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   612 VHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEM 691
Cdd:TIGR00606  461 KELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   692 NEKTLEKLD----------VKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELeAKMDEQKNHHQQQVDSiIK 761
Cdd:TIGR00606  541 TKDKMDKDEqirkiksrhsDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL-ASLEQNKNHINNELES-KE 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   762 EHEVSIQR------TEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK 835
Cdd:TIGR00606  619 EQLSSYEDklfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFIS 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   836 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMeQKVKSLTQVYESKLEDG 915
Cdd:TIGR00606  699 DLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI-QRLKNDIEEQETLLGTI 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   916 NKEQEQTKQILVEKEnmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEK--KMEKVKQKAKEMQetlkkK 993
Cdd:TIGR00606  778 MPEEESAKVCLTDVT--IMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqhELDTVVSKIELNR-----K 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   994 LLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANsagisdavSRLETNQKEQIESLTEV-HRRELNDVISIWEKKLN 1072
Cdd:TIGR00606  851 LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFE--------EQLVELSTEVQSLIREIkDAKEQDSPLETFLEKDQ 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1073 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQ-DTTLNELQEQLKQKSAHVNSLAQDetk 1151
Cdd:TIGR00606  923 QEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQkETELNTVNAQLEECEKHQEKINED--- 999

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1152 lkahLEKLEVDLNKSLKENTFLQEQLVELKMlaeedKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSE 1231
Cdd:TIGR00606 1000 ----MRLMRQDIDTQKIQERWLQDNLTLRKR-----ENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNH 1070


                   ....
gi 578805993  1232 ELAI 1235
Cdd:TIGR00606 1071 VLAL 1074
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
293-680 8.95e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 8.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  293 EDGTSVKTLETLQQRVKRQENLLKRC---KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMA---EKTKLIT 366
Cdd:PRK02224  200 EEKDLHERLNGLESELAELDEEIERYeeqREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAEterEREELAE 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  367 QLRDAKNLIEQLEQDKGMVIAETKR---------QMHETLEMKEEE----IAQLRSRIKQMTTQGEELREQ--------K 425
Cdd:PRK02224  280 EVRDLRERLEELEEERDDLLAEAGLddadaeaveARREELEDRDEElrdrLEECRVAAQAHNEEAESLREDaddleeraE 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  426 EKSERAAfeELEKALSTAQKTEEARRKLKAEMDEQIKTIEKT----------SEEERISLQQELSRVKQEVVDVMK--KS 493
Cdd:PRK02224  360 ELREEAA--ELESELEEAREAVEDRREEIEELEEEIEELRERfgdapvdlgnAEDFLEELREERDELREREAELEAtlRT 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  494 SEEQIAKLQKLHEkelARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTES- 571
Cdd:PRK02224  438 ARERVEEAEALLE---AGKCPECGQPVEGSPHvETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERl 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  572 ENKLRDLQQEAETYRTRILELESSLEkSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKT---ELESLKHQQDALWT 648
Cdd:PRK02224  515 EERREDLEELIAERRETIEEKRERAE-ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAElnsKLAELKERIESLER 593

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 578805993  649 -EKLQVLKQQYQTEMEKLREKCEQ--EKETLLKDK 680
Cdd:PRK02224  594 iRTLLAAIADAEDEIERLREKREAlaELNDERRER 628
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 456-1166 1.21e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.89  E-value: 1.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   456 EMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIaklqklhekelarkEQELTKKLQTREREFQEQMKVAL 535
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQM--------------ERDAMADIRRRESQSQEDLRNQL 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   536 EKSQSEYLKISQEKEQQESLALEELELQKKAILTEsENKLRDLqqeaetyRTRILELESSLEKSLQENKNQSkdlAVHLE 615
Cdd:pfam15921  148 QNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-EGVLQEI-------RSILVDFEEASGKKIYEHDSMS---TMHFR 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   616 AeknkHNKEITVMVEKHKTELESLKHQQDALwTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIifqaHIEEMNEKT 695
Cdd:pfam15921  217 S----LGSAISKILRELDTEISYLKGRIFPV-EDQLEALKSESQNKIELLLQQHQDRIEQLISEHEV----EITGLTEKA 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   696 LEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL-EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEK-- 772
Cdd:pfam15921  288 SSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERdq 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   773 ------ALKDQINQLELLLKERDKHLKEHQAH--------------VENLEADIKRSEGELQQASAKLDVFQSYQSATHE 832
Cdd:pfam15921  368 fsqesgNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQME 447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   833 QTKAY----EEQLAQLQQKLLDLETERILLTKQVAEVEAQKkdvcTELDAHKIQVQDLMQQLEKQNSEME------QKVK 902
Cdd:pfam15921  448 RQMAAiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKK----MTLESSERTVSDLTASLQEKERAIEatnaeiTKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   903 SLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREgQKKEIEILTQKLsakEDSIHILNEEYETKFKNQEKKMEKVK-- 980
Cdd:pfam15921  524 SRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE-KDKVIEILRQQI---ENMTQLVGQHGRTAGAMQVEKAQLEKei 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   981 -------QKAKEMQETLKKKLLDQEAKLKK-ELENTALELSQKE--------KQFNAKMLEMAQANSAGISDAVSRLET- 1043
Cdd:pfam15921  600 ndrrlelQEFKILKDKKDAKIRELEARVSDlELEKVKLVNAGSErlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVl 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1044 -----NQKEQIESLTEVHRRELNDVISIWEKKLNQ-QAEELQEIHEI--------QLQEKEQEVAELKQKILLFGCEKEE 1109
Cdd:pfam15921  680 krnfrNKSEEMETTTNKLKMQLKSAQSELEQTRNTlKSMEGSDGHAMkvamgmqkQITAKRGQIDALQSKIQFLEEAMTN 759

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 578805993  1110 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKS 1166
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKA 816
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2193-2232 1.22e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 44.27  E-value: 1.22e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 578805993  2193 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2232
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1479-1707 1.31e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 50.31  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1479 TVKELQ----IQLELKSKEayEKDEQINLLKEELDQQNKRFDCLKGEME----DDKSKMEKKESNLETELKSQTARIMEL 1550
Cdd:PRK05771   21 VLEALHelgvVHIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPklnpLREEKKKVSVKSLEELIKDVEEELEKI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1551 EDHITQKTIEIESLNEVLKNYNQQKDIehkelVQKLQHF----QELGEEKD-----NRVKEAEEKILTLENQVYsmKAEL 1621
Cdd:PRK05771   99 EKEIKELEEEISELENEIKELEQEIER-----LEPWGNFdldlSLLLGFKYvsvfvGTVPEDKLEELKLESDVE--NVEY 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1622 ETKKKELEHVNLSVKSK-----EEELKALE-DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLS 1695
Cdd:PRK05771  172 ISTDKGYVYVVVVVLKElsdevEEELKKLGfERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLA 251

                         250
                  ....*....|..
gi 578805993 1696 ELNTKLQERERE 1707
Cdd:PRK05771  252 LYEYLEIELERA 263
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 576-1137 1.46e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 1.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  576 RDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK 655
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  656 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTD 735
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  736 KMKQELEAKMDEQKNHHQQQVDsiIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 815
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAE--LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  816 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVcteLDAHKIQVQDLMQQLEKQNS 895
Cdd:COG1196   454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV---KAALLLAGLRGLAGAVAVLI 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  896 EMEQKVKSLTQVYESKLEDGNkeQEQTKQILVEKENMILQMREGQKKEIEILTQK-LSAKEDSIHILNEEYETKFKNQEK 974
Cdd:COG1196   531 GVEAAYEAALEAALAAALQNI--VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRaRAALAAALARGAIGAAVDLVASDL 608

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  975 KMEKVKQKAKEMQ---ETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKmLEMAQANSAGISDAVSRLETNQKEQIES 1051
Cdd:COG1196   609 READARYYVLGDTllgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG-GSLTGGSRRELLAALLEAEAELEELAER 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1052 LTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFgcEKEEMNKEITWLKEEGVKQDTTLNEL 1131
Cdd:COG1196   688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE--ELLEEEELLEEEALEELPEPPDLEEL 765


                  ....*.
gi 578805993 1132 QEQLKQ 1137
Cdd:COG1196   766 ERELER 771
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1598-2117 1.56e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 1.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1598 NRVKEAEEKILT----LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsesaaklaELKRKAEqKIAAIKK 1673
Cdd:PRK03918  175 KRRIERLEKFIKrtenIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEELKE-EIEELEK 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1674 QLlsqmeEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGcvQKT 1753
Cdd:PRK03918  246 EL-----ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR--LSR 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1754 YEEKISVLQRNLTEKEKLLQRVGQEKEETVsshfemrcQYQERLIKLEhaeaKQHEDQSMIGHLQEELEEKNKKYSLIVA 1833
Cdd:PRK03918  319 LEEEINGIEERIKELEEKEERLEELKKKLK--------ELEKRLEELE----ERHELYEEAKAKKEELERLKKRLTGLTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1834 QHVEKEGgKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDS----CLVRQKEVHRVEMEELTSKY-------- 1901
Cdd:PRK03918  387 EKLEKEL-EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkCPVCGRELTEEHRKELLEEYtaelkrie 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1902 EKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEF----KLAGAEREKQKLGKEIVRLQKDLRMLR 1977
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1978 KEhQQELEILKKEYDQEREEKIKQEQEDLELKHNstLKQLMREFNTQLAQKEQELEMTIKETIN-----KAQEVEAELLE 2052
Cdd:PRK03918  546 KE-LEKLEELKKKLAELEKKLDELEEELAELLKE--LEELGFESVEELEERLKELEPFYNEYLElkdaeKELEREEKELK 622

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578805993 2053 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2117
Cdd:PRK03918  623 KLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEK 687
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
315-542 1.57e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  315 LKRCKETIQSHKEQCTLLTSEKEALQE--QLDERLQELEKIKdlHMAEKTKLITQLRDAKNLIEQLEQDkgmviaetkrq 392
Cdd:COG4913   237 LERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLR--AALRLWFAQRRLELLEAELEELRAE----------- 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  393 mhetLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER 472
Cdd:COG4913   304 ----LARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASA 379

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  473 islqQELSRVKQEVVDVMKKSSEEQIAKLQKLHekELARKEQELTKKLQTREREFQeqmkvALEKSQSEY 542
Cdd:COG4913   380 ----EEFAALRAEAAALLEALEEELEALEEALA--EAEAALRDLRRELRELEAEIA-----SLERRKSNI 438
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1601-1909 1.73e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 1.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1601 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE--SESAAKLAELKRKAEQKIAAIKKQLLSQ 1678
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGeiEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1679 MEEKEEQykkgtESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIvprsaknvaaYTEQEEADSQGCVQKTYEEKI 1758
Cdd:TIGR02169  750 EQEIENV-----KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI----------PEIQAELSKLEEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1759 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1838
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDEL 894

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578805993  1839 EGGKNNIQAKQN-LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMeELTSKYEKLQALQQ 1909
Cdd:TIGR02169  895 EAQLRELERKIEeLEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL-SLEDVQAELQRVEE 965
PTZ00121 PTZ00121
MAEBL; Provisional
 1530-2116 2.18e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 2.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1530 EKKESNLETELKSQTARIMELEDHITQKTIEIES-LNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKIL 1608
Cdd:PTZ00121 1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARkAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1609 TLENQVYSMKAE----LETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEE 1684
Cdd:PTZ00121 1162 DARKAEEARKAEdakkAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1685 QYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEE--KISVLQ 1762
Cdd:PTZ00121 1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAK 1321

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1763 RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELE------EKNKKYSLIVAQHV 1836
Cdd:PTZ00121 1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADaakkkaEEKKKADEAKKKAE 1401

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1837 EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKP 1916
Cdd:PTZ00121 1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE 1481

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1917 TELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKL-----GKEIVRLQKDLRMLRKEHQQELEILKKEY 1991
Cdd:PTZ00121 1482 AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeeAKKADEAKKAEEKKKADELKKAEELKKAE 1561

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1992 DQEREEKIKQEQED--LELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQE--VEAELLESHQEETNQL--LKKI 2065
Cdd:PTZ00121 1562 EKKKAEEAKKAEEDknMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEakIKAEELKKAEEEKKKVeqLKKK 1641

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 578805993 2066 AEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEE 2116
Cdd:PTZ00121 1642 EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1117-1742 2.43e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.63  E-value: 2.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1117 LKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1196
Cdd:TIGR04523   24 YKNIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1197 KLKTTDEEFQSLKSshEKSNKSLEDKSLE-FKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKT------NAILSR 1269
Cdd:TIGR04523  104 DLSKINSEIKNDKE--QKNKLEVELNKLEkQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEelenelNLLEKE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1270 ISHCQHRTTKVKEALLIKTCTVSELEAqlrqLTEEQNTLNIsfqqathQLEEKENQIKSMKADIESLVTEKEALQKEGGN 1349
Cdd:TIGR04523  182 KLNIQKNIDKIKNKLLKLELLLSNLKK----KIQKNKSLES-------QISELKKQNNQLKDNIEKKQQEINEKTTEISN 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1350 QQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS------LSEKEAAISSLRKQY 1423
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNkelkseLKNQEKKLEEIQNQI 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1424 DEEK---CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQN---TVKELQIQLELKSKEAYEK 1497
Cdd:TIGR04523  331 SQNNkiiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesQINDLESKIQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1498 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMekkeSNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDI 1577
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEI----KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1578 EHKELVQKLQHFQELGEEKdnrvKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1657
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1658 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAA 1737
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDQ-KEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641


                   ....*
gi 578805993  1738 YTEQE 1742
Cdd:TIGR04523  642 KLKQE 646
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1938-2165 2.64e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.67  E-value: 2.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1938 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEhQQELEILKKEYDQEREEKIKQEQEDLELKHNST--LK 2015
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER-LANLERQLEELEAQLEELESKLDELAEELAELEekLE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2016 QLMREFNtQLAQKEQELEMTIKETINKAQEVEAELLE------SHQEETNQLLKKIAEKDDDLKRTAKRYE----EILDA 2085
Cdd:TIGR02168  348 ELKEELE-SLEAELEELEAELEELESRLEELEEQLETlrskvaQLELQIASLNNEIERLEARLERLEDRRErlqqEIEEL 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2086 REEEMTAKVRDLQTQLEELQKKYQQKLEQEENPgndNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2165
Cdd:TIGR02168  427 LKKLEEAELKELQAELEELEEELEELQEELERL---EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
PRK12704 PRK12704
phosphodiesterase; Provisional
 1569-1682 3.03e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.01  E-value: 3.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1569 KNYNQQKDIEHKELVQKL--QHFQELgEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALE 1646
Cdd:PRK12704   52 EAIKKEALLEAKEEIHKLrnEFEKEL-RERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKE 130

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 578805993 1647 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEK 1682
Cdd:PRK12704  131 EELEELIEEQLQELERISGLTAEEAKEILLEKVEEE 166
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1469-1692 3.04e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.67  E-value: 3.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1469 AQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET---ELKSQTA 1545
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEErreELGERAR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1546 RIMELEDHITQKTI--EIESLNEVLKNYNQQKDIE--HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAEL 1621
Cdd:COG3883    94 ALYRSGGSVSYLDVllGSESFSDFLDRLSALSKIAdaDADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578805993 1622 ETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTES 1692
Cdd:COG3883   174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1290-1825 3.35e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.27  E-value: 3.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1290 TVSELEAQLRQLTEEQNTLNISFQQATHQL----------EEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES 1359
Cdd:PRK02224  207 RLNGLESELAELDEEIERYEEQREQARETRdeadevleehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRE 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1360 CITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEekceLLDQVQDLS 1438
Cdd:PRK02224  287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLeECRVAAQAHNEEAESLREDADD----LEERAEELR 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1439 FKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKE-ELDQQNKRFDC 1517
Cdd:PRK02224  363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAElEATLRTARERV 442

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1518 LKGEMEDDKSK-----MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHK--ELVQKLQHFQ 1590
Cdd:PRK02224  443 EEAEALLEAGKcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRieRLEERREDLE 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1591 ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsESAAKLAELKRKAEqkiaa 1670
Cdd:PRK02224  523 ELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA-ELKERIESLERIRT----- 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1671 ikkqLLSQMEEKEEQYKKGTE--SHLSELNTKLQEREREvhiLEEKLKSVESSQSETLIvprsaknvaayteqEEADSQG 1748
Cdd:PRK02224  597 ----LLAAIADAEDEIERLREkrEALAELNDERRERLAE---KRERKRELEAEFDEARI--------------EEAREDK 655

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1749 CVQKTYEEKISVLQRNLTEKE-KLLQRVGQEKEE--TVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKN 1825
Cdd:PRK02224  656 ERAEEYLEQVEEKLDELREERdDLQAEIGAVENEleELEELRERREALENRVEALEALYDEAEELESMYGDLRAELRQRN 735
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
341-904 4.58e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 4.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  341 EQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHEtLEMKEEEIAQLRSRIKQMTTQGEE 420
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSE-LPELREELEKLEKEVKELEELKEE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  421 LREQKEK--SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIE--KTSEEERISLQQELSRVKQEVVDVMKKSS-- 494
Cdd:PRK03918  240 IEELEKEleSLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSrl 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  495 EEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEqmkvaLEKSQSEYLKISQEKEQqeslaleeLELQKKAILTESE 572
Cdd:PRK03918  320 EEEINGIEERIKEleEKEERLEELKKKLKELEKRLEE-----LEERHELYEEAKAKKEE--------LERLKKRLTGLTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  573 NKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITV---MVEKHKTELESLKHQQDALWTE 649
Cdd:PRK03918  387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCgreLTEEHRKELLEEYTAELKRIEK 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  650 KLQVLKQQyqteMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR-HKLEEELS 728
Cdd:PRK03918  467 ELKEIEEK----ERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKlIKLKGEIK 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  729 VLKDQTDKmKQELE---AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKhLKEHQAHVENLEAD 805
Cdd:PRK03918  543 SLKKELEK-LEELKkklAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKE 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  806 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERilLTKQVAEVEAQKKdvctELDAHKIQVQD 885
Cdd:PRK03918  621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLE--LSRELAGLRAELE----ELEKRREEIKK 694

                         570
                  ....*....|....*....
gi 578805993  886 LMQQLEKQNSEMEQKVKSL 904
Cdd:PRK03918  695 TLEKLKEELEEREKAKKEL 713
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 476-804 4.95e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.58  E-value: 4.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   476 QQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQeltkkLQTREREFQEQMKVALEKSQsEYLKISQEKEQQESL 555
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAE-----MDRQAAIYAEQERMAMERER-ELERIRQEERKRELE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   556 ALEElelQKKAILTESENKLRDLQQEAETYRTRIL-ELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEitvmvEKHKT 634
Cdd:pfam17380  364 RIRQ---EEIAMEISRMRELERLQMERQQKNERVRqELEAARKVKILEEERQRKIQQQKVEMEQIRAEQE-----EARQR 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   635 ELESLKHQQdALWTEKLQVLKQQYQTEMEKLRE-KCEQEKETLLKDKEIIFQAHIEEMNEKTLEKldvkqtELESLSSEL 713
Cdd:pfam17380  436 EVRRLEEER-AREMERVRLEEQERQQQVERLRQqEEERKRKKLELEKEKRDRKRAEEQRRKILEK------ELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   714 SEVLKARHKLEEElsvLKDQTDKMKQELEAKMDEQKNHHQQQVdsiikEHEVSIQRTEKALKDQINQLELLLKERD--KH 791
Cdd:pfam17380  509 IEEERKRKLLEKE---MEERQKAIYEEERRREAEEERRKQQEM-----EERRRIQEQMRKATEERSRLEAMEREREmmRQ 580

                          330
                   ....*....|...
gi 578805993   792 LKEHQAHVENLEA 804
Cdd:pfam17380  581 IVESEKARAEYEA 593
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 302-976 4.95e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.81  E-value: 4.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   302 ETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLdeRLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ---- 377
Cdd:TIGR00618  215 DTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL--KKQQLLKQLRARIEELRAQEAVLEETQERINRarka 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   378 ----LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 453
Cdd:TIGR00618  293 aplaAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISC 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   454 KAEMDEQ----IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHekelARKEQELTKKLQTREREF-- 527
Cdd:TIGR00618  373 QQHTLTQhihtLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH----AKKQQELQQRYAELCAAAit 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   528 -QEQMKVALEKSQSEYLKISQEKEQQESLALEELElQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 606
Cdd:TIGR00618  449 cTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   607 SKDLAVHLEaeknkhnkeitvmVEKHKTELESLKHQQDALwTEKLQVLKQQYQTEMEKLREKCEQEKET-----LLKDKE 681
Cdd:TIGR00618  528 RRMQRGEQT-------------YAQLETSEEDVYHQLTSE-RKQRASLKEQMQEIQQSFSILTQCDNRSkedipNLQNIT 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   682 IIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKnHHQQQVDSIIK 761
Cdd:TIGR00618  594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR-EHALSIRVLPK 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   762 EHEVSIQRTEKAL----------KDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDvfQSYQSATH 831
Cdd:TIGR00618  673 ELLASRQLALQKMqsekeqltywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALN--QSLKELMH 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   832 EQTKAYEEQLAQLQQKLLDLETERILLTkqvaeveaQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESK 911
Cdd:TIGR00618  751 QARTVLKARTEAHFNNNEEVTAALQTGA--------ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQ 822

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578805993   912 LEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKM 976
Cdd:TIGR00618  823 CETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 530-1230 5.21e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.68  E-value: 5.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   530 QMKVALEKSQSEYLKISQEKEQQESLALEELELQKKaiLTESENKLRDLQQEAETYRTRILELESSLEKSLQEN------ 603
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFG--YKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKrdelng 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   604 --KNQSKDLA---VHLEAEKNKHNKEITVMVEKHKTELESLKHQQD---------ALWTEKLQVLKQQYQTEMEKLREKC 669
Cdd:pfam12128  309 elSAADAAVAkdrSELEALEDQHGAFLDADIETAAADQEQLPSWQSelenleerlKALTGKHQDVTAKYNRRRSKIKEQN 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   670 EQEKETLLKDKEIIFQAHIE--EMNEKTLEKLDvkQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDE 747
Cdd:pfam12128  389 NRDIAGIKDKLAKIREARDRqlAVAEDDLQALE--SELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   748 QKNhhQQQVDSIIKEHEVSIQRTEkALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ 827
Cdd:pfam12128  467 ENF--DERIERAREEQEAANAEVE-RLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKE 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   828 SATHEQTKAyeeqlaqlqqklLDLETERILLTKQVAEV-EAQKKDVCT----ELDAHKIQVQDLMQqlekqnseMEQKVK 902
Cdd:pfam12128  544 APDWEQSIG------------KVISPELLHRTDLDPEVwDGSVGGELNlygvKLDLKRIDVPEWAA--------SEEELR 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   903 SLTQVYESKLEDGNKEQEQTKQILVEKENmilQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQK 982
Cdd:pfam12128  604 ERLDKAEEALQSAREKQAAAEEQLVQANG---ELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSA 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   983 AKEMQ--ETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRREL 1060
Cdd:pfam12128  681 NERLNslEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDL 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1061 N--DVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELKQkillfgCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQK 1138
Cdd:pfam12128  761 AslGVDPDVIAKLKREIRTLERKIE-RIAVRRQEVLRYFD------WYQETWLQRRPRLATQLSNIERAISELQQQLARL 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1139 SAHVNS-LAQDETKLKAhLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSeLTSKLKTTDEEFQSLKSSHEKSNK 1217
Cdd:pfam12128  834 IADTKLrRAKLEMERKA-SEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDYLSESVKK 911

                          730
                   ....*....|...
gi 578805993  1218 SLEDKSLEFKKLS 1230
Cdd:pfam12128  912 YVEHFKNVIADHS 924
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1265-1827 5.57e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.68  E-value: 5.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1265 AILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQlteEQNTLNISFQQATHQLEEKENQ--------IKSMKADIE-- 1334
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG---ELSAADAAVAKDRSELEALEDQhgafldadIETAAADQEql 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1335 -SLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKE 1413
Cdd:pfam12128  350 pSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLE 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1414 AAISSLRkqydEEKCELLDQVQDLSFKVD--TLSKEKISALEQVDDWSNKfsewkkkAQSRFTQHQNTVKELQIQLELKS 1491
Cdd:pfam12128  430 AGKLEFN----EEEYRLKSRLGELKLRLNqaTATPELLLQLENFDERIER-------AREEQEAANAEVERLQSELRQAR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1492 KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELED-HITQKTIEI--ESLNEVL 1568
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELlHRTDLDPEVwdGSVGGEL 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1569 KNYNQQKDIEHKELVQKLQHFQELGEEKD---NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1645
Cdd:pfam12128  579 NLYGVKLDLKRIDVPEWAASEEELRERLDkaeEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1646 EDRLESESAAK---LAELKRKAEQKIAAIKKQlLSQMEEKEEQYKKGTESHLSELNTKLQEREREVhilEEKLKSVESSQ 1722
Cdd:pfam12128  659 FDEKQSEKDKKnkaLAERKDSANERLNSLEAQ-LKQLDKKHQAWLEEQKEQKREARTEKQAYWQVV---EGALDAQLALL 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1723 SETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQY----QERLI 1798
Cdd:pfam12128  735 KAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWlqrrPRLAT 814

                          570       580
                   ....*....|....*....|....*....
gi 578805993  1799 KLEHAEAKQHEDQSMIGHLQEELEEKNKK 1827
Cdd:pfam12128  815 QLSNIERAISELQQQLARLIADTKLRRAK 843
PTZ00121 PTZ00121
MAEBL; Provisional
 299-624 6.29e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 6.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  299 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKnlIEQL 378
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK--AEEA 1612

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  379 EQdkgmviAETKRQMHETLEMKEEE---IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARrklKA 455
Cdd:PTZ00121 1613 KK------AEEAKIKAEELKKAEEEkkkVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK---KA 1683

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  456 EMDEQIKTIEKTSEEERISLQQELSRVKQEVV---DVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 532
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLK 1763

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  533 VALEKSQSEYLK-----ISQEKEQQESLALEELELQKKAILTESENkLRDLQQEAETYRTRILELESSLEKSLQENKNQS 607
Cdd:PTZ00121 1764 KEEEKKAEEIRKekeavIEEELDEEDEKRRMEVDKKIKDIFDNFAN-IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ 1842

                         330
                  ....*....|....*..
gi 578805993  608 KDLAVHLEAEKNKHNKE 624
Cdd:PTZ00121 1843 LEEADAFEKHKFNKNNE 1859
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
368-839 8.00e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 8.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  368 LRDAKNLIEQLEQDkgmvIAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSE---------RAAFEELE 437
Cdd:PRK02224  182 LSDQRGSLDQLKAQ----IEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADevleeheerREELETLE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  438 KALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-------------------ERISLQQE-LSRVKQEVVDVMkksseEQ 497
Cdd:PRK02224  258 AEIEDLRETIAETEREREELAEEVRDLRERLEEleeerddllaeaglddadaEAVEARREeLEDRDEELRDRL-----EE 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  498 IAKLQKLHEKElARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK-----AILTESE 572
Cdd:PRK02224  333 CRVAAQAHNEE-AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapVDLGNAE 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  573 NKLRDLQQEAETYRTRILELESSLeKSLQENKNQSKDLavhLEA----------EKNKHNKEIT---VMVEKHKTELESL 639
Cdd:PRK02224  412 DFLEELREERDELREREAELEATL-RTARERVEEAEAL---LEAgkcpecgqpvEGSPHVETIEedrERVEELEAELEDL 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  640 KHQQDALwTEKLQVLKQQYQTE--MEKLREKCEQEKEtLLKDKEiifqAHIEEMNEKTLEKLDVKQTELESLSSELSEVL 717
Cdd:PRK02224  488 EEEVEEV-EERLERAEDLVEAEdrIERLEERREDLEE-LIAERR----ETIEEKRERAEELRERAAELEAEAEEKREAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  718 KARHKLEEELSVLKdqtdkmkqELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKaLKDQINQLELLLKERDKHLKEH 795
Cdd:PRK02224  562 EAEEEAEEAREEVA--------ELNSKLAELKERIESleRIRTLLAAIADAEDEIER-LREKREALAELNDERRERLAEK 632

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 578805993  796 QAHVENLEADIkrSEGELQQASAKLDVFQSYQSATHEQTKAYEE 839
Cdd:PRK02224  633 RERKRELEAEF--DEARIEEAREDKERAEEYLEQVEEKLDELRE 674
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 387-608 9.93e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  387 AETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAfEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 466
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  467 TSEE------ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLheKELARKEQELTKKLQTREREFQEQmKVALEKSQS 540
Cdd:COG4942    98 ELEAqkeelaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL--KYLAPARREQAEELRADLAELAAL-RAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578805993  541 EyLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSK 608
Cdd:COG4942   175 E-LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 633-1715 1.12e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 47.74  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   633 KTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNeKTLEKLDVKQTELESLSSE 712
Cdd:TIGR01612  695 KAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLN-KILEDFKNKEKELSNKIND 773

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   713 LSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI----IKEHEVSIQRTE-KALKDQI-NQLELLLK 786
Cdd:TIGR01612  774 YAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIktisIKEDEIFKIINEmKFMKDDFlNKVDKFIN 853

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   787 ERDKHLKEHQAHVENLEADIKRSEGEL--QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILL-TKQVA 863
Cdd:TIGR01612  854 FENNCKEKIDSEHEQFAELTNKIKAEIsdDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVDEYIKICEnTKESI 933

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   864 EVEAQKKDVCTELDAHKIQVQDLMQQLEK------QNSEMEQKV---KSLTQVYESKLEDGNKEQEQTKQILVE-----K 929
Cdd:TIGR01612  934 EKFHNKQNILKEILNKNIDTIKESNLIEKsykdkfDNTLIDKINeldKAFKDASLNDYEAKNNELIKYFNDLKAnlgknK 1013

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   930 ENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEmqetlkkkLLDQEAKLKKELENTA 1009
Cdd:TIGR01612 1014 ENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIE--------LLNKEILEEAEINITN 1085

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1010 L-ELSQKEKQFN----AKMLEMAQANSAG-ISDAVSRLETNQKEQIESLTEVHRRELNDVisiweKKLNQQAEELQEIHE 1083
Cdd:TIGR01612 1086 FnEIKEKLKHYNfddfGKEENIKYADEINkIKDDIKNLDQKIDHHIKALEEIKKKSENYI-----DEIKAQINDLEDVAD 1160

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1084 IQLQEKEQEVAELKQKILLFGCEK-----EEMNKEITWLKEEGvKQDTTLNELQEQLKQKSAHVNSL---AQDETKLKAH 1155
Cdd:TIGR01612 1161 KAISNDDPEEIEKKIENIVTKIDKkkniyDEIKKLLNEIAEIE-KDKTSLEEVKGINLSYGKNLGKLfleKIDEEKKKSE 1239

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1156 -----LEKLEVDLNKSLKentflQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1230
Cdd:TIGR01612 1240 hmikaMEAYIEDLDEIKE-----KSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDF 1314

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1231 EELAIQLDICCKKTEALLEAKTNelinisSSKTNAILSRISHCQHrttkvkealLIKTCTVSELEAQLRQLTEEQNTLNi 1310
Cdd:TIGR01612 1315 SEESDINDIKKELQKNLLDAQKH------NSDINLYLNEIANIYN---------ILKLNKIKKIIDEVKEYTKEIEENN- 1378

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1311 sfQQATHQLEEKENQIKSMKADIeslvtekealqkeggNQQQAASEKESCITQlkKELSENINAVTLMKEELKEKKVEIS 1390
Cdd:TIGR01612 1379 --KNIKDELDKSEKLIKKIKDDI---------------NLEECKSKIESTLDD--KDIDECIKKIKELKNHILSEESNID 1439

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1391 SLSKQLTDLNvqlqNSISLSEKEAAISSLRKQYDEeKCELLDQVQDLSFKVDTLsKEKISALEQVDDWSNKFSEWKKKAQ 1470
Cdd:TIGR01612 1440 TYFKNADENN----ENVLLLFKNIEMADNKSQHIL-KIKKDNATNDHDFNINEL-KEHIDKSKGCKDEADKNAKAIEKNK 1513

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1471 SRFTQHQNTVKEL---QIQLELKSKEAYEKDEQINLLKEELDQQNKRFdcLKGEMEDDKSKMEKKEsnlETELKSQTARI 1547
Cdd:TIGR01612 1514 ELFEQYKKDVTELlnkYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFI--LEAEKSEQKIKEIKKE---KFRIEDDAAKN 1588

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1548 MELEDHITQKTIEIESL-NEVLKNYNQQKDI-----EHKELVQKLQHFQElgEEKDNRVKEAEEKILTLENQVYSMKAE- 1620
Cdd:TIGR01612 1589 DKSNKAAIDIQLSLENFeNKFLKISDIKKKIndclkETESIEKKISSFSI--DSQDTELKENGDNLNSLQEFLESLKDQk 1666

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1621 --LETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSElN 1698
Cdd:TIGR01612 1667 knIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDP-N 1745

                         1130
                   ....*....|....*..
gi 578805993  1699 TKLQEREREVHILEEKL 1715
Cdd:TIGR01612 1746 EKLEEYNTEIGDIYEEF 1762
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 974-1721 1.94e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.96  E-value: 1.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   974 KKMEKVKQKAKEMQETL--KKKLLDQEAKLKKELENTALELSQKEKQfnakmLEMAQANSAGISDAVSRLETNQKEQies 1051
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQItsKEAQLESSREIVKSYENELDPLKNRLKE-----IEHNLSKIMKLDNEIKALKSRKKQM--- 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1052 ltEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1131
Cdd:TIGR00606  282 --EKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRH 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1132 QEQLKQKSAHVNSLAqdetkLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSS 1211
Cdd:TIGR00606  360 QEHIRARDSLIQSLA-----TRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1212 HEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1285
Cdd:TIGR00606  435 KKGLGRTIELKKEILEKKQEELKFvikelqQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1286 IKTCTVSELEAQLRQLTEEQNTLnisfQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK 1365
Cdd:TIGR00606  515 RKLRKLDQEMEQLNHHTTTRTQM----EMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTR 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1366 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL-------------LD 1432
Cdd:TIGR00606  591 DRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRamlagatavysqfIT 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1433 QVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQN 1512
Cdd:TIGR00606  671 QLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1513 KRFDCLKGEMEDDKSKMEKKESNLETELKSQTA----------------RIMELEDHITQKTIEIESLN-----EVLKNY 1571
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESakvcltdvtimerfqmELKDVERKIAQQAAKLQGSDldrtvQQVNQE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1572 NQQKDIEHKELVQKLQHFQELGEE----------KDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEE 1641
Cdd:TIGR00606  831 KQEKQHELDTVVSKIELNRKLIQDqqeqiqhlksKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQ 910

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1642 LKALEDRLE------SESAAKLAELKRKAEQKIAAIKKQ----------LLSQMEEKEEQYKKGTESHLSELNTKLQERE 1705
Cdd:TIGR00606  911 DSPLETFLEkdqqekEELISSKETSNKKAQDKVNDIKEKvknihgymkdIENKIQDGKDDYLKQKETELNTVNAQLEECE 990

                          810
                   ....*....|....*.
gi 578805993  1706 REVHILEEKLKSVESS 1721
Cdd:TIGR00606  991 KHQEKINEDMRLMRQD 1006
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 366-519 2.83e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 46.23  E-value: 2.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  366 TQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMttqgeelrEQKEKSERAAFEELekalstaqk 445
Cdd:COG0542   411 EELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEAL--------KARWEAEKELIEEI--------- 473

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  446 teearRKLKAEMDEQ---IKTIEKTSEEERISLQQELSRVKQEVvdvmkksSEEQIAK---------LQKLHEKE---LA 510
Cdd:COG0542   474 -----QELKEELEQRygkIPELEKELAELEEELAELAPLLREEV-------TEEDIAEvvsrwtgipVGKLLEGErekLL 541


                  ....*....
gi 578805993  511 RKEQELTKK 519
Cdd:COG0542   542 NLEEELHER 550
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 333-530 2.86e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  333 TSEKEALQEQLDE---RLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDkgmvIAETKRQMHETlemkEEEIAQLRS 409
Cdd:COG4942    19 ADAAAEAEAELEQlqqEIAELEKELAALKKEEKALLKQLAALERRIAALARR----IRALEQELAAL----EAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  410 RIKQMTTQGEELREQKEKSERAA-----------------FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-- 470
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALyrlgrqpplalllspedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEle 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578805993  471 -----------ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLheKELARKEQELTKKLQTREREFQEQ 530
Cdd:COG4942   171 aeraeleallaELEEERAALEALKAERQKLLARLEKELAELAAEL--AELQQEAEELEALIARLEAEAAAA 239
PRK12704 PRK12704
phosphodiesterase; Provisional
 1066-1196 3.21e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.92  E-value: 3.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1066 IWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGceKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSL 1145
Cdd:PRK12704   24 VRKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEA--KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 578805993 1146 AQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1196
Cdd:PRK12704  102 LELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTA 152
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1414-2041 3.64e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 3.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1414 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVddwsnkFSEWKKKAQSRFTQHQNTVKELQIQLELKSKE 1493
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKASSARSQ 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1494 AYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkeSNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQ 1573
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLR---SELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1574 qkdiEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESES 1653
Cdd:pfam15921  371 ----ESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1654 AAKLAELKRKAE--QKIAAIKKQLLSQMEE-----KEEQYKKGT----ESHLSELNTKLQEREREVHILEEKLKSVESSQ 1722
Cdd:pfam15921  447 ERQMAAIQGKNEslEKVSSLTAQLESTKEMlrkvvEELTAKKMTlessERTVSDLTASLQEKERAIEATNAEITKLRSRV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1723 SETLIVPRSAKNVAAYTEQEEADSQGcVQKTYEEKISVLQRNLTEKEKLLQRVGQ----------EKEETVSSHFEMRCQ 1792
Cdd:pfam15921  527 DLKLQELQHLKNEGDHLRNVQTECEA-LKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagamqvEKAQLEKEINDRRLE 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1793 YQERLIKLEHAEAKQHEDQSMIGHLQEEleeknkKYSLIVAQHVEKEGGKNNIQAKQNL----ENVFDDVQKTLQEKELT 1868
Cdd:pfam15921  606 LQEFKILKDKKDAKIRELEARVSDLELE------KVKLVNAGSERLRAVKDIKQERDQLlnevKTSRNELNSLSEDYEVL 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1869 CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLvqpkllSNMEAQHNDL 1948
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI------DALQSKIQFL 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1949 EFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEILKKEydqerEEKIKQEQEDLELKHNSTLKQLMREFNTQL 2025
Cdd:pfam15921  754 EEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmagELEVLRSQ-----ERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          650
                   ....*....|....*.
gi 578805993  2026 AQKEQELEMTIKETIN 2041
Cdd:pfam15921  829 RQEQESVRLKLQHTLD 844
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 869-1100 4.10e-04

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 45.61  E-value: 4.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   869 KKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES-KLEDGNKEQEQtkQILVEKENMILQMREGQKKEIEIL 947
Cdd:pfam09726  393 KPDALVRLEQDIKKLKAELQASRQTEQELRSQISSLTSLERSlKSELGQLRQEN--DLLQTKLHNAVSAKQKDKQTVQQL 470

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   948 TQKLSAKEDSI----HILNEEYETKFKNQEKKMEKVKQKA---KEMQETLKKKLLDQEAKLKK-------------ELEN 1007
Cdd:pfam09726  471 EKRLKAEQEARasaeKQLAEEKKRKKEEEATAARAVALAAasrGECTESLKQRKRELESEIKKlthdiklkeeqirELEI 550

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1008 TALELSQKEKqfNAKMLEMAQANSAGISDAVSRLEtnqkeqiESLTEVHRRELnDVISiwekKLNQQAEELqEIHEIQLQ 1087
Cdd:pfam09726  551 KVQELRKYKE--SEKDTEVLMSALSAMQDKNQHLE-------NSLSAETRIKL-DLFS----ALGDAKRQL-EIAQGQIY 615

                          250
                   ....*....|...
gi 578805993  1088 EKEQEVAELKQKI 1100
Cdd:pfam09726  616 QKDQEIKDLKQKI 628
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 718-906 4.19e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 4.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  718 KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQqvdsiIKEHEVSIQRTEKALKD---QINQLELLLKERDKHLKE 794
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARRIRAleqELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  795 HQAHVENLEADIKR------------------SEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 856
Cdd:COG4942    95 LRAELEAQKEELAEllralyrlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 578805993  857 LLTKQVAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 906
Cdd:COG4942   175 ELEALLAELEEERA----ALEALKAERQKLLARLEKELAELAAELAELQQ 220
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
296-608 4.31e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 4.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  296 TSVKTLETLQQRVKRQENLLKRCK-ETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDlHMAEKTKLITQLRDAKNL 374
Cdd:PRK03918  359 ERHELYEEAKAKKEELERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKK-EIKELKKAIEELKKAKGK 437

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  375 I-----EQLEQDKGMVIAETKRQMHETLEMKEEEIAQLR----------------SRIKQMTTQGEELREQKEKSERAAF 433
Cdd:PRK03918  438 CpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERklrkelrelekvlkkeSELIKLKELAEQLKELEEKLKKYNL 517

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  434 EELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSE--EERISLQQELSRVKQEVVDVMKKSS----------EEQIAKL 501
Cdd:PRK03918  518 EELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEElkKKLAELEKKLDELEEELAELLKELEelgfesveelEERLKEL 597

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  502 QKLHEKEL----ARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRD 577
Cdd:PRK03918  598 EPFYNEYLelkdAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAG 677

                         330       340       350
                  ....*....|....*....|....*....|.
gi 578805993  578 LQQEAETYRTRILELESSLEKSLQENKNQSK 608
Cdd:PRK03918  678 LRAELEELEKRREEIKKTLEKLKEELEEREK 708
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
374-534 4.70e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 45.23  E-value: 4.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  374 LIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQ-KEKSERAafEELEKALSTAQKteEARRK 452
Cdd:COG2433   385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAElEEKDERI--ERLERELSEARS--EERRE 460

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  453 LKaemdeqiKTIEKTSEEERIS-LQQELSRVKQEVvdvmkKSSEEQIAKLQKLHEKElARKEQELTKKLQ--TRE--REF 527
Cdd:COG2433   461 IR-------KDREISRLDREIErLERELEEERERI-----EELKRKLERLKELWKLE-HSGELVPVKVVEkfTKEaiRRL 527


                  ....*..
gi 578805993  528 QEQMKVA 534
Cdd:COG2433   528 EEEYGLK 534
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1562-1714 5.97e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 5.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1562 ESLNEVLKnynqqkDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVysmkAELETKKKELEHvnlSVKSKEEE 1641
Cdd:COG2433   376 LSIEEALE------ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQV----ERLEAEVEELEA---ELEEKDER 442

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578805993 1642 LKALEDRLESESAAKLAELKRKAE-QKIAAIKKQLLSQMEEKEEqykkgtesHLSELNTKLqEREREVHILEEK 1714
Cdd:COG2433   443 IERLERELSEARSEERREIRKDREiSRLDREIERLERELEEERE--------RIEELKRKL-ERLKELWKLEHS 507
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1151-2009 7.45e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 7.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1151 KLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEfKKLS 1230
Cdd:pfam02463  170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE-LLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1231 EELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNI 1310
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1311 SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1390
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1391 S---LSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDwSNKFSEWKK 1467
Cdd:pfam02463  409 LlleLARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ-LVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1468 KAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTA-- 1545
Cdd:pfam02463  488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKlv 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1546 RIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAE------EKILTLENQVYSMKA 1619
Cdd:pfam02463  568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEgilkdtELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1620 ELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNT 1699
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1700 KLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKisvlQRNLTEKEKLLQRVGQEK 1779
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEK----LKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1780 EETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMigHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQ 1859
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEE--LALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1860 KTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRnkptelleenteEKSKSHLVQPKLLS 1939
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE------------EPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1940 NMEAQHNDLEFKLAGAEREKQKLGKEIVRLqkDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELK 2009
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMA--IEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1128-1719 7.99e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 7.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1128 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELkmlaEEDKRKVSELTSKLKTTDEEFQS 1207
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPEL----REELEKLEKEVKELEELKEEIEE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1208 LK---SSHEKSNKSLEDKSLEFKKLSEELaiqldiccKKTEALLEAKTNELINISSSKTNAIlsRISHCQHRTTKVKEAL 1284
Cdd:PRK03918  243 LEkelESLEGSKRKLEEKIRELEERIEEL--------KKEIEELEEKVKELKELKEKAEEYI--KLSEFYEEYLDELREI 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1285 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLvteKEALQKEGGNQQQAASEKESCITQL 1364
Cdd:PRK03918  313 EKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY---EEAKAKKEELERLKKRLTGLTPEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1365 KKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNvqlQNSISLSEKEAAISSLRKQYDEEkcELLDQVQDLSFKVDTL 1444
Cdd:PRK03918  390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELK---KAIEELKKAKGKCPVCGRELTEE--HRKELLEEYTAELKRI 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1445 SKEKISALEQVDDWSNKFSEWKK--KAQSRFTQHQNTVKELqiqlelksKEAYEKDEQINLlkEELDQQNKRFDCLKGEM 1522
Cdd:PRK03918  465 EKELKEIEEKERKLRKELRELEKvlKKESELIKLKELAEQL--------KELEEKLKKYNL--EELEKKAEEYEKLKEKL 534

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1523 eddkSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKdNRVKE 1602
Cdd:PRK03918  535 ----IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEY-LELKD 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1603 AEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQlLSQMEEK 1682
Cdd:PRK03918  610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAE-LEELEKR 688

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 578805993 1683 EEQYKKGTEShLSELNTKLQEREREVHILEEKLKSVE 1719
Cdd:PRK03918  689 REEIKKTLEK-LKEELEEREKAKKELEKLEKALERVE 724
46 PHA02562
endonuclease subunit; Provisional
 1130-1373 8.16e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 8.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1130 ELQEQLKQKSAHVNSLaqdETKLKAHlEKLEVDLNKSLKEN-TFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSL 1208
Cdd:PHA02562  178 ELNQQIQTLDMKIDHI---QQQIKTY-NKNIEEQRKKNGENiARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1209 KSSHEKSNKSLEDKSLEFKKLSEELAIQLD--ICCKKTEALLEakTNELINisssktnAILSRISHCQHRTTKVKEAlli 1286
Cdd:PHA02562  254 SAALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQISE--GPDRIT-------KIKDKLKELQHSLEKLDTA--- 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1287 ktctVSELEAQLRQLTEEQNTLNisfqqathqleEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKK 1366
Cdd:PHA02562  322 ----IDELEEIMDEFNEQSKKLL-----------ELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386


                  ....*..
gi 578805993 1367 ELSENIN 1373
Cdd:PHA02562  387 ELDKIVK 393
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1491-1724 8.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1491 SKEAYEKDEQINLLKEELDQQNKRFDCLKGE---MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLnev 1567
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEekaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL--- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1568 lknyNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEhvnlSVKSKEEELKALED 1647
Cdd:COG4942    96 ----RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE----ELRADLAELAALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578805993 1648 RLESESAAKLAELKRKAEQkiaaiKKQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSE 1724
Cdd:COG4942   168 ELEAERAELEALLAELEEE-----RAALEALKAERQKLLAR-LEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 175-953 8.74e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 8.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   175 MDSEAEDLVGNSDSLN-----KEQLIQRLRRMERSLSSYRGKYSEELQMDQQAKKHLQEEFDASLEEKDQyisvLQTQVS 249
Cdd:TIGR02168  279 LEEEIEELQKELYALAneisrLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE----LKEELE 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   250 LLKQRLrngpmnvdvlkplpqlepqAEVFTKEENPESdgepvvedgtsvkTLETLQQRVKRQENLLKRCKETIQSHKEQC 329
Cdd:TIGR02168  355 SLEAEL-------------------EELEAELEELES-------------RLEELEEQLETLRSKVAQLELQIASLNNEI 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   330 TLLTSEKEALQEQLDERLQELEKI-KDLHMAEKTKLITQLRDAKNLIEQLEqdkgmviaETKRQMHETLEMKEEEIAQLR 408
Cdd:TIGR02168  403 ERLEARLERLEDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQ--------EELERLEEALEELREELEEAE 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   409 SRIKQMTTQGEELReQKEKSERAAFEELEKaLSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVD 488
Cdd:TIGR02168  475 QALDAAERELAQLQ-ARLDSLERLQENLEG-FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   489 vmkKSSEEQIAKLQKLHEKELAR---------KEQELTKKLQTREREFQEQMKVA--LEKSQSEYLKISQEKEQQESLAL 557
Cdd:TIGR02168  553 ---ENLNAAKKAIAFLKQNELGRvtflpldsiKGTEIQGNDREILKNIEGFLGVAkdLVKFDPKLRKALSYLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   558 EELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKhNKEITVMVEKHKTELE 637
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEK-IAELEKALAELRKELE 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   638 SLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLdvkqteleslsselsevl 717
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL------------------ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   718 karHKLEEELSVLKDQtdkmKQELEAKMDEQKNHHQQQvDSIIKEHEVSIQRTEKALKDQINQLELLLKERDkhlkEHQA 797
Cdd:TIGR02168  771 ---EEAEEELAEAEAE----IEELEAQIEQLKEELKAL-REALDELRAELTLLNEEAANLRERLESLERRIA----ATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   798 HVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDvcteld 877
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE------ 912

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578805993   878 ahkiqVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA 953
Cdd:TIGR02168  913 -----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1978-2161 9.41e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 9.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1978 KEHQQELEILKKEYDQEREEKIKQEQEDLELKHNStLKQLMREFNTQLAQKEQELEmtikETINKAQEVEAELLESHQEE 2057
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEE-LEAELEELEAELAELEAELE----ELRLELEELELELEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2058 tNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEnpgndnvtimELQTQLAQKTT 2137
Cdd:COG1196   291 -YELLAELARLEQDIARLEERRRE-LEERLEELEEELAELEEELEELEEELEELEEELE----------EAEEELEEAEA 358

                         170       180
                  ....*....|....*....|....
gi 578805993 2138 LISDSKLKEQEFREQIHNLEDRLK 2161
Cdd:COG1196   359 ELAEAEEALLEAEAELAEAEEELE 382
PRK01156 PRK01156
chromosome segregation protein; Provisional
 774-1370 1.11e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.12  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  774 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ---SATHEQTKAYEEQLAQLQQKLLD 850
Cdd:PRK01156  188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALnelSSLEDMKNRYESEIKTAESDLSM 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  851 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQnSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKE 930
Cdd:PRK01156  268 ELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENK-KQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKS 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  931 nmilqmregQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEA--KLKKELENT 1008
Cdd:PRK01156  347 ---------RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAikKELNEINVK 417

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1009 ALELSQKEKQFNAKMLEMAQaNSAGISDAVSRLETNQKEQIESlTEVHRRELNDVISIWEKKLNQQAEELQEIhEIQLQE 1088
Cdd:PRK01156  418 LQDISSKVSSLNQRIRALRE-NLDELSRNMEMLNGQSVCPVCG-TTLGEEKSNHIINHYNEKKSRLEEKIREI-EIEVKD 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1089 KEQEVAELKQkiLLFGCEKEEMNKEITwlkeegvkQDTTLNELQEQLKQKSAHVNSLAQDETKLKA--------HLEKLE 1160
Cdd:PRK01156  495 IDEKIVDLKK--RKEYLESEEINKSIN--------EYNKIESARADLEDIKIKINELKDKHDKYEEiknrykslKLEDLD 564

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1161 VDLNKSLKENTFLQEQLVE-LKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEF---KKLSEELAIQ 1236
Cdd:PRK01156  565 SKRTSWLNALAVISLIDIEtNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLnnkYNEIQENKIL 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1237 LDICCKKTEALLEaKTNELINISSSKtNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQAT 1316
Cdd:PRK01156  645 IEKLRGKIDNYKK-QIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDIN 722

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 578805993 1317 HQLEEKenqiKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSE 1370
Cdd:PRK01156  723 ETLESM----KKIKKAIGDLKRLREAFDKSGVPAMIRKSASQAMTSLTRKYLFE 772
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1527-2167 1.20e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1527 SKMEKKESNLETELKSQTARIMELEDHItqKTIEIESLNEVLKNYNQQKDiehkelvqklqHFQELGEEKDNRVKEAEEK 1606
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQL--EALKSESQNKIELLLQQHQD-----------RIEQLISEHEVEITGLTEK 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1607 ILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESEsaakLAELKRKAEQKIAAIKKQL-LSQMEEKEEQ 1685
Cdd:pfam15921  287 ASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSE----LREAKRMYEDKIEELEKQLvLANSELTEAR 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1686 YKKGTESHLS-ELNTKLQEREREVHILEEKLkSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-- 1762
Cdd:pfam15921  363 TERDQFSQESgNLDDQLQKLLADLHKREKEL-SLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKse 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1763 -RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL-EHAEAKQ---HEDQSMIGHLQEELEEKNKKyslIVAQHVE 1837
Cdd:pfam15921  442 cQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVvEELTAKKmtlESSERTVSDLTASLQEKERA---IEATNAE 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1838 KEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLvrqkevhrvemEELTSKYEKLQALQQMDGRNKPT 1917
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVI-----------EILRQQIENMTQLVGQHGRTAGA 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1918 ELLEENTEEKS----KSHLVQPKLLSNM-EAQHNDLEFKLAGAEREKQKL---GKEIVRLQKDLRMLRKEHQQELEILKK 1989
Cdd:pfam15921  588 MQVEKAQLEKEindrRLELQEFKILKDKkDAKIRELEARVSDLELEKVKLvnaGSERLRAVKDIKQERDQLLNEVKTSRN 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1990 EYDQEREEkikqeqedlelkhnstLKQLMREFNtqlaQKEQELEMTIKETINKAQEVEAELleshqEETNQLLKKIAEKD 2069
Cdd:pfam15921  668 ELNSLSED----------------YEVLKRNFR----NKSEEMETTTNKLKMQLKSAQSEL-----EQTRNTLKSMEGSD 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2070 DDLKRTAKryeeildAREEEMTAKvrdlQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEF 2149
Cdd:pfam15921  723 GHAMKVAM-------GMQKQITAK----RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGE 791

                          650
                   ....*....|....*...
gi 578805993  2150 REQIHNLEDRLKKYEKNV 2167
Cdd:pfam15921  792 LEVLRSQERRLKEKVANM 809
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 299-1742 1.33e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 44.27  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   299 KTLETLQQRVKRQENLLKRCKETIQSHKE--QCTLLTSEKEALQEQLDERLQELEKIKDLHmAEKTKLITQLRDAKNLIE 376
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQINDLEDvaDKAISNDDPEEIEKKIENIVTKIDKKKNIY-DEIKKLLNEIAEIEKDKT 1207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   377 QLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE-------------------ELE 437
Cdd:TIGR01612 1208 SLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEmgiemdikaemetfnishdDDK 1287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   438 KALSTAQKTEEARRKLKaemDEQIKTIEKTSEEERI-----SLQQELSRVKQEVVDVMKKSSE----EQIAKLQKLheKE 508
Cdd:TIGR01612 1288 DHHIISKKHDENISDIR---EKSLKIIEDFSEESDIndikkELQKNLLDAQKHNSDINLYLNEianiYNILKLNKI--KK 1362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   509 LARKEQELTKKLQtrerEFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIltesenklRDLQQEAETYRTR 588
Cdd:TIGR01612 1363 IIDEVKEYTKEIE----ENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDI--------DECIKKIKELKNH 1430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   589 ILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEK-------HKTELESLKHQQD------------ALWTE 649
Cdd:TIGR01612 1431 ILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKkdnatndHDFNINELKEHIDkskgckdeadknAKAIE 1510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   650 KLQVLKQQYQTEMEKLREK-----CEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 724
Cdd:TIGR01612 1511 KNKELFEQYKKDVTELLNKysalaIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDK 1590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   725 EELSVLKDQTDkmKQELEAKMDEQKNhHQQQVDSIIKEHEvSIQRTEKALkdQINQLELLLKERDKHLKEHQAHVENLEA 804
Cdd:TIGR01612 1591 SNKAAIDIQLS--LENFENKFLKISD-IKKKINDCLKETE-SIEKKISSF--SIDSQDTELKENGDNLNSLQEFLESLKD 1664

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   805 DIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVaeVEAQKKDVCTELDAHKIQVQ 884
Cdd:TIGR01612 1665 QKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKEL--IEPTIENLISSFNTNDLEGI 1742

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   885 DLMQQLEKQNSEMEQKVKSLTQVYE---SKLEDGNKEQ---EQTKQILVEKENMILQMREGQKK-----------EIEIL 947
Cdd:TIGR01612 1743 DPNEKLEEYNTEIGDIYEEFIELYNiiaGCLETVSKEPityDEIKNTRINAQNEFLKIIEIEKKsksylddieakEFDRI 1822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   948 TQKLSAKEDSIHI-LNEEYET---KFKNQEKKMEKVKQKAKE---------MQETLKKKLLDQEAKLKKELENTALELSQ 1014
Cdd:TIGR01612 1823 INHFKKKLDHVNDkFTKEYSKineGFDDISKSIENVKNSTDEnllfdilnkTKDAYAGIIGKKYYSYKDEAEKIFINISK 1902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1015 KEKQFNAKMlemaqANSAGIS-------DAVSRLETNQKEQI----------ESLTEVhRRELNDVISIWEKKLNQQAEE 1077
Cdd:TIGR01612 1903 LANSINIQI-----QNNSGIDlfdniniAILSSLDSEKEDTLkfipspekepEIYTKI-RDSYDTLLDIFKKSQDLHKKE 1976

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1078 LQEIHEI----QLQEKEQEVAELKQKILLFGCEKEEMNKEITWLkeegVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK 1153
Cdd:TIGR01612 1977 QDTLNIIfenqQLYEKIQASNELKDTLSDLKYKKEKILNDVKLL----LHKFDELNKLSCDSQNYDTILELSKQDKIKEK 2052

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1154 A-----HLEKLEVDLNKSLKENTFLQ-----EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKS 1223
Cdd:TIGR01612 2053 IdnyekEKEKFGIDFDVKAMEEKFDNdikdiEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTEIKIIEDKI 2132

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1224 LEFKKLSEELAIQLDICCKKTEA-LLEAKTNELINISSSKTNAilsrishcqhrttkvkeallikTCTVSELEAQLRQLT 1302
Cdd:TIGR01612 2133 IEKNDLIDKLIEMRKECLLFSYAtLVETLKSKVINHSEFITSA----------------------AKFSKDFFEFIEDIS 2190

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1303 EEQNTlNISFQQATHQLEEKENQIKSMKADIESlvTEKEALQKEggnqqQAASEKESCITQLKKELSENINAVTLMKEEL 1382
Cdd:TIGR01612 2191 DSLND-DIDALQIKYNLNQTKKHMISILADATK--DHNNLIEKE-----KEATKIINNLTELFTIDFNNADADILHNNKI 2262

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1383 kekkveisslskQLTDLNVQLQNSislsekeaaISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEkisaleqvddwsnkF 1462
Cdd:TIGR01612 2263 ------------QIIYFNSELHKS---------IESIKKLYKKINAFKLLNISHINEKYFDISKE--------------F 2307

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1463 SEWKKKAQSRFTQHQNTVKELqiqlelkskEAYEKDEQINLLKEELDQQNKRFDCLKgEMEDDKSKMEKKESNLETELKS 1542
Cdd:TIGR01612 2308 DNIIQLQKHKLTENLNDLKEI---------DQYISDKKNIFLHALNENTNFNFNALK-EIYDDIINRENKADEIENINNK 2377

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1543 QTARIMELEDHITQKTIEIESL----------NEVLKNYNQQKDIEH-----KELVQKLQHFQELgeekDNRVKEAEEKI 1607
Cdd:TIGR01612 2378 ENENIMQYIDTITKLTEKIQDIlifvttyendNNIIKQHIQDNDENDvskikDNLKKTIQSFQEI----LNKIDEIKAQF 2453

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1608 LTlENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK 1687
Cdd:TIGR01612 2454 YG-GNNINNIIITISQNANDVKNHFSKDLTIENELIQIQKRLEDIKNAAHEIRSEQITKYTNAIHNHIEEQFKKIENNSN 2532

                         1530      1540      1550      1560      1570
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 578805993  1688 KGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQE 1742
Cdd:TIGR01612 2533 KDEVYKINEIDNIIEKIINYNKEPEVKLHAIIDNKNEFASIIPDIKNLIALIESE 2587
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
784-1208 1.50e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  784 LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERIL-----L 858
Cdd:COG4717    51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLlqllpL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  859 TKQVAEVEAQKKDVCTELDAHKIQVQDLmQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMRE 938
Cdd:COG4717   131 YQELEALEAELAELPERLEELEERLEEL-RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLA 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  939 GQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKA-------KEMQETLKKKLLDQEAKLKKELENTALE 1011
Cdd:COG4717   210 ELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIaaallalLGLGGSLLSLILTIAGVLFLVLGLLALL 289

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1012 LSQKEKQFNAKMLEMAQANSAGISDAVSRLE-TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE 1090
Cdd:COG4717   290 FLLLAREKASLGKEAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELE 369

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1091 QEVAELKQKillFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQ--KSAHVNSLAQDETKLKAHLEKLEVDLNKSLK 1168
Cdd:COG4717   370 QEIAALLAE---AGVEDEEELRAALEQAEEYQELKEELEELEEQLEEllGELEELLEALDEEELEEELEELEEELEELEE 446

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 578805993 1169 ENTFLQEQLVELK--MLAEEDKRKVSELTSKLKTTDEEFQSL 1208
Cdd:COG4717   447 ELEELREELAELEaeLEQLEEDGELAELLQELEELKAELREL 488
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1507-1678 1.59e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1507 ELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiehkeLVQKL 1586
Cdd:COG1579    14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG-----NVRNN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1587 QHFQELGEEKDNrvkeAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA---AKLAELKRK 1663
Cdd:COG1579    89 KEYEALQKEIES----LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAeleAELEELEAE 164

                         170
                  ....*....|....*
gi 578805993 1664 AEQKIAAIKKQLLSQ 1678
Cdd:COG1579   165 REELAAKIPPELLAL 179
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1938-2114 1.63e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1938 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKE----YDQEREEKIK----QEQEDLELK 2009
Cdd:COG4942    57 LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlralYRLGRQPPLAlllsPEDFLDAVR 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2010 HNSTLKQLMREFNTQLAQKEQELEM--TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDARE 2087
Cdd:COG4942   137 RLQYLKYLAPARREQAEELRADLAElaALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAE-LAAEL 215

                         170       180
                  ....*....|....*....|....*..
gi 578805993 2088 EEMTAKVRDLQTQLEELQKKYQQKLEQ 2114
Cdd:COG4942   216 AELQQEAEELEALIARLEAEAAAAAER 242
PRK12704 PRK12704
phosphodiesterase; Provisional
 334-471 1.85e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  334 SEKEALQEQLDERLQELEKIKDLhmaeKTKLITQLRDAKNLIEQLEQdKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 413
Cdd:PRK12704   47 AKKEAEAIKKEALLEAKEEIHKL----RNEFEKELRERRNELQKLEK-RLLQKEENLDRKLELLEKREEELEKKEKELEQ 121

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578805993  414 MTTQGEELREQKEKSERAAFEELEK--ALSTAQKT----EEARRKLKAEMDEQIKTIEKTSEEE 471
Cdd:PRK12704  122 KQQELEKKEEELEELIEEQLQELERisGLTAEEAKeillEKVEEEARHEAAVLIKEIEEEAKEE 185
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 299-502 2.32e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  299 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKD----LHMAEKTKLITQLRDAKNL 374
Cdd:COG4942    55 KQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRalyrLGRQPPLALLLSPEDFLDA 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  375 IEQLEQDKGmvIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERaafeELEKALSTAQKTEEARRKLK 454
Cdd:COG4942   135 VRRLQYLKY--LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA----ALEALKAERQKLLARLEKEL 208

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 578805993  455 AEMDEQIKTIEKtseeERISLQQELSRVKQEVVDVMKKSSEEQIAKLQ 502
Cdd:COG4942   209 AELAAELAELQQ----EAEELEALIARLEAEAAAAAERTPAAGFAALK 252
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1069-1663 2.41e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.17  E-value: 2.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1069 KKLNQQAEELQEIHEIQLQEKEQEVAELkqkiLLFGCEKEEMNKEITWLKEEGVKQdttLNELQEQLKQKSAHVNSLAQD 1148
Cdd:pfam05483  218 KEDHEKIQHLEEEYKKEINDKEKQVSLL----LIQITEKENKMKDLTFLLEESRDK---ANQLEEKTKLQDENLKELIEK 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1149 ETKLKAHLEKLEVDLNKSLKENTFLQEQLvelkmlaEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1228
Cdd:pfam05483  291 KDHLTKELEDIKMSLQRSMSTQKALEEDL-------QIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1229 LSEELAIQLDicckKTEALLEAKTNELinisssktnailsrishcQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTL 1308
Cdd:pfam05483  364 LLRTEQQRLE----KNEDQLKIITMEL------------------QKKSSELEEMTKFKNNKEVELEELKKILAEDEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1309 --NISFQQATHQLEEKENQIKSMKADIESLVTEKEA-LQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEK 1385
Cdd:pfam05483  422 deKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIqLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1386 KVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEW 1465
Cdd:pfam05483  502 KELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYE 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1466 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC-------LKGEMEDDKSKMEKKESNLET 1538
Cdd:pfam05483  582 VLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAyeikvnkLELELASAKQKFEEIIDNYQK 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1539 ELKSQTARIMELEDHITQKTIEIESLNEVLKNYN---QQKDIEHKELVQKLQH-FQELGEEKDNRVKEAEEKiltlENQV 1614
Cdd:pfam05483  662 EIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDkrcQHKIAEMVALMEKHKHqYDKIIEERDSELGLYKNK----EQEQ 737

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 578805993  1615 YSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRK 1663
Cdd:pfam05483  738 SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 340-899 3.24e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 3.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   340 QEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIA------ETKRQMHETLEMKEEEIAQLRSRIKQ 413
Cdd:pfam01576   21 QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAArkqeleEILHELESRLEEEEERSQQLQNEKKK 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   414 MTTQGEELREQKEKSERAafeelEKALSTAQKTEEARRKlkaEMDEQIKTIEktseEERISLQQELSRVKQEVVDVMKKS 493
Cdd:pfam01576  101 MQQHIQDLEEQLDEEEAA-----RQKLQLEKVTTEAKIK---KLEEDILLLE----DQNSKLSKERKLLEERISEFTSNL 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   494 SEEQ-----IAKLQKLHEKELARKEQELTKKLQTRERefQEQMKVALEKSQSEYlkisqekeQQESLALEELELQKKAIL 568
Cdd:pfam01576  169 AEEEekaksLSKLKNKHEAMISDLEERLKKEEKGRQE--LEKAKRKLEGESTDL--------QEQIAELQAQIAELRAQL 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   569 TESENKLRDLQQEAETYRTRilelESSLEKSLQENKNQSKDLAVHLEAEKNKHNKeitvmVEKHKTELEslkHQQDALWT 648
Cdd:pfam01576  239 AKKEEELQAALARLEEETAQ----KNNALKKIRELEAQISELQEDLESERAARNK-----AEKQRRDLG---EELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   649 EKLQVLKQQyqTEMEKLREKCEQEKETL---LKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 725
Cdd:pfam01576  307 ELEDTLDTT--AAQQELRSKREQEVTELkkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   726 ELSVLKDQTDKMKQeleAKMDEQknHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLlkerdkhlkehQAHVENLEAD 805
Cdd:pfam01576  385 ENAELQAELRTLQQ---AKQDSE--HKRKKLEGQLQELQARLSESERQRAELAEKLSKL-----------QSELESVSSL 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   806 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQD 885
Cdd:pfam01576  449 LNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSD 528

                          570
                   ....*....|....
gi 578805993   886 LMQQLEKQNSEMEQ 899
Cdd:pfam01576  529 MKKKLEEDAGTLEA 542
PRK12704 PRK12704
phosphodiesterase; Provisional
 923-1091 3.25e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  923 KQILVEKENMILQMREGQKKEIEILTQK--LSAKEDsIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEaK 1000
Cdd:PRK12704   30 EAKIKEAEEEAKRILEEAKKEAEAIKKEalLEAKEE-IHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLE-K 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1001 LKKELENTALELSQKEKQFNAKMLEMAQAnsagISDAVSRLetnqkEQIESLTEVHRRELndVISIWEKKLNQQAEELqe 1080
Cdd:PRK12704  108 REEELEKKEKELEQKQQELEKKEEELEEL----IEEQLQEL-----ERISGLTAEEAKEI--LLEKVEEEARHEAAVL-- 174

                         170
                  ....*....|.
gi 578805993 1081 IHEIQLQEKEQ 1091
Cdd:PRK12704  175 IKEIEEEAKEE 185
PRK09039 PRK09039
peptidoglycan -binding protein;
354-518 3.39e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.26  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  354 KDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAetkrQMHETLEMKEEEiaqlRSRIKQMTTQGEELREQKEKseRAAf 433
Cdd:PRK09039   51 KDSALDRLNSQIAELADLLSLERQGNQDLQDSVA----NLRASLSAAEAE----RSRLQALLAELAGAGAAAEG--RAG- 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  434 eELEKALSTAQKT-EEARRKLkAEMDEQIKtiektseeeriSLQQELSRVkQEVVDVMKKSSEEQIAKLQKLHEK---EL 509
Cdd:PRK09039  120 -ELAQELDSEKQVsARALAQV-ELLNQQIA-----------ALRRQLAAL-EAALDASEKRDRESQAKIADLGRRlnvAL 185


                  ....*....
gi 578805993  510 ARKEQELTK 518
Cdd:PRK09039  186 AQRVQELNR 194
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1942-2111 3.43e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1942 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRK-------------------EHQQELEILKKEYDQERE-----E 1997
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQErrealqrlaeyswdeidvaSAEREIAELEAELERLDAssddlA 688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1998 KIKQEQEDLELKHNsTLKQLMREFNTQLAQKEQELEmTIKETINKAQEVEAELLESHQEETNQLL-KKIAEKDDDlkRTA 2076
Cdd:COG4913   689 ALEEQLEELEAELE-ELEEELDELKGEIGRLEKELE-QAEEELDELQDRLEAAEDLARLELRALLeERFAAALGD--AVE 764

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 578805993 2077 KRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQK 2111
Cdd:COG4913   765 RELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1530-1708 3.52e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1530 EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE--HKELVQKLQHFQELgEEKDNRVKEAEEKI 1607
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAsaEREIAELEAELERL-DASSDDLAALEEQL 694

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1608 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKqllsqmEEKEEQYK 1687
Cdd:COG4913   695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG------DAVERELR 768

                         170       180
                  ....*....|....*....|.
gi 578805993 1688 KGTESHLSELNTKLQEREREV 1708
Cdd:COG4913   769 ENLEERIDALRARLNRAEEEL 789
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 613-1685 3.62e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 3.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   613 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEK------LQVLKQQYQTEMEKLREKCEQEKETL--LKDKEIIF 684
Cdd:pfam01576   50 QAETELCAEAEEMRARLAARKQELEEILHELESRLEEEeersqqLQNEKKKMQQHIQDLEEQLDEEEAARqkLQLEKVTT 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   685 QAHIEEMNEKTLEKLDvkqteleslssELSEVLKARHKLEEELSvlkDQTDKMKQELEAKMDEQKNHHQQQvdSIIKEHE 764
Cdd:pfam01576  130 EAKIKKLEEDILLLED-----------QNSKLSKERKLLEERIS---EFTSNLAEEEEKAKSLSKLKNKHE--AMISDLE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   765 VSIQRTEKALKDQIN---QLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDvfqSYQSATHEQTKAYEEQL 841
Cdd:pfam01576  194 ERLKKEEKGRQELEKakrKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE---EETAQKNNALKKIRELE 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   842 AQLQQKLLDLETERILLTKqvaeVEAQKKDVCTELDAHKIQV----------QDLMQQLEKQNSEMEQKVKSLTQVYESK 911
Cdd:pfam01576  271 AQISELQEDLESERAARNK----AEKQRRDLGEELEALKTELedtldttaaqQELRSKREQEVTELKKALEEETRSHEAQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   912 LEDGNKEQEQTKQILVEKENMILQMR---EGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEmQE 988
Cdd:pfam01576  347 LQEMRQKHTQALEELTEQLEQAKRNKanlEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSE-SE 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   989 TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAgISDAVSRLETNQKEQIESLTEVhrRELNDVISIWE 1068
Cdd:pfam01576  426 RQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQ-LQDTQELLQEETRQKLNLSTRL--RQLEDERNSLQ 502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1069 KKLNQQAEELQEIhEIQLQEKEQEVAELKQKIllfgcekEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQD 1148
Cdd:pfam01576  503 EQLEEEEEAKRNV-ERQLSTLQAQLSDMKKKL-------EEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKT 574

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1149 ETKLKAHLEKLEVDLNKslkentflQEQLVelkmlaeedkrkvseltsklkttdeefqslkSSHEKSNKSLEdkslefKK 1228
Cdd:pfam01576  575 KNRLQQELDDLLVDLDH--------QRQLV-------------------------------SNLEKKQKKFD------QM 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1229 LSEELAIQLDICCKKTEALLEAKTNELINISSSKtnailsrishcqhrttkvkeALLIKTCTVSELEAQLRQLTEEQNTL 1308
Cdd:pfam01576  610 LAEEKAISARYAEERDRAEAEAREKETRALSLAR--------------------ALEEALEAKEELERTNKQLRAEMEDL 669

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1309 NISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAvtlmkeELKEKKVE 1388
Cdd:pfam01576  670 VSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQA------RDEQGEEK 743

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1389 ISSLSKQLTDLNVQLQNSislSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1468
Cdd:pfam01576  744 RRQLVKQVRELEAELEDE---RKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARAS 820

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1469 AQSRFTQHQNTVKELQ------IQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKS 1542
Cdd:pfam01576  821 RDEILAQSKESEKKLKnleaelLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEE 900

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1543 QTARIMELEDHITQKTIEIESLNEVL----------KNYNQQKDIEHKELVQKLQHFQELGEEKdnrvkeAEEKILTLEN 1612
Cdd:pfam01576  901 EQSNTELLNDRLRKSTLQVEQLTTELaaerstsqksESARQQLERQNKELKAKLQEMEGTVKSK------FKSSIAALEA 974

                         1050      1060      1070      1080      1090      1100      1110
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578805993  1613 QVYSMKAELETKKKELEHVNLSVKSKEEELKalEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1685
Cdd:pfam01576  975 KIAQLEEQLEQESRERQAANKLVRRTEKKLK--EVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEE 1045
46 PHA02562
endonuclease subunit; Provisional
 1498-1711 4.45e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 4.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1498 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQK-D 1576
Cdd:PHA02562  187 DMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAaK 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1577 IEHK-ELVQKLQHFQELGEE---KDNRVKEAEEKIltlenqvysmkAELETKKKELEHVNLSVKSKEEELKALEDRLeSE 1652
Cdd:PHA02562  267 IKSKiEQFQKVIKMYEKGGVcptCTQQISEGPDRI-----------TKIKDKLKELQHSLEKLDTAIDELEEIMDEF-NE 334

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578805993 1653 SAAKLAELKRKAEQKIAAIK------KQLLSQMEEKEEQYK------KGTESHLSELNTKLQEREREVHIL 1711
Cdd:PHA02562  335 QSKKLLELKNKISTNKQSLItlvdkaKKVKAAIEELQAEFVdnaeelAKLQDELDKIVKTKSELVKEKYHR 405
HlpA COG2825
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...
 1956-2043 4.57e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442073 [Multi-domain]  Cd Length: 171  Bit Score: 40.20  E-value: 4.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1956 EREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDlelkhnstLKQLMREFNTQLAQKEQELEMT 2035
Cdd:COG2825    49 EKEFKKRQAELQKLEKELQALQEKLQKEAATLSEEERQKKERELQKKQQE--------LQRKQQEAQQDLQKRQQELLQP 120


                  ....*...
gi 578805993 2036 IKETINKA 2043
Cdd:COG2825   121 ILEKIQKA 128
PRK12704 PRK12704
phosphodiesterase; Provisional
 1653-1829 4.57e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1653 SAAKLAELKRKAEQKIA-------AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKsvesSQSET 1725
Cdd:PRK12704   29 AEAKIKEAEEEAKRILEeakkeaeAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLD----RKLEL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1726 LivprSAKNVAAYTEQEEADSQgcvQKTYEEKISVLQRNLTEKEKLLQRV-GQEKEETvsshfemrcqyqeRLIKLEHAE 1804
Cdd:PRK12704  105 L----EKREEELEKKEKELEQK---QQELEKKEEELEELIEEQLQELERIsGLTAEEA-------------KEILLEKVE 164

                         170       180
                  ....*....|....*....|....*.
gi 578805993 1805 AK-QHEDQSMIGHLQEELEEKNKKYS 1829
Cdd:PRK12704  165 EEaRHEAAVLIKEIEEEAKEEADKKA 190
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
300-616 4.59e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 42.33  E-value: 4.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  300 TLETLQQRVKRQENLLK--RCKETIQSHKEQ---CTLltSEKEALQEQLDERLQELEkikdLHMAEKTKLITQLRDAKNL 374
Cdd:PRK02224  434 TLRTARERVEEAEALLEagKCPECGQPVEGSphvETI--EEDRERVEELEAELEDLE----EEVEEVEERLERAEDLVEA 507

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  375 IEQLEQDKgmviaetkrqmhETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLK 454
Cdd:PRK02224  508 EDRIERLE------------ERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVA 575

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  455 ------AEMDEQIKTIEK--TSEEERISLQQELSRVKQevvdvmkksseeqiaKLQKLHEKELARKEQELTKKLQTRERE 526
Cdd:PRK02224  576 elnsklAELKERIESLERirTLLAAIADAEDEIERLRE---------------KREALAELNDERRERLAEKRERKRELE 640

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  527 fqeqmkvalEKSQSEYLKISQEKEQQEslaleelelqkKAILTESENKLRDLQQEAETYRTRILELESSLEkSLQENKNQ 606
Cdd:PRK02224  641 ---------AEFDEARIEEAREDKERA-----------EEYLEQVEEKLDELREERDDLQAEIGAVENELE-ELEELRER 699

                         330
                  ....*....|
gi 578805993  607 SKDLAVHLEA 616
Cdd:PRK02224  700 REALENRVEA 709
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 787-1220 4.61e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.12  E-value: 4.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   787 ERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAThEQTKAYEeqlaqlqQKLLDLETERILLTKQVAEVE 866
Cdd:pfam10174  182 ERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDP-AKTKALQ-------TVIEMKDTKISSLERNIRDLE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   867 AQKKDVCTELDAHKIQVQDLMQQLEKQNSE---MEQKVKSLTQvyesklEDGNKEQEQtkQILVEKENMILQMREGQKKE 943
Cdd:pfam10174  254 DEVQMLKTNGLLHTEDREEEIKQMEVYKSHskfMKNKIDQLKQ------ELSKKESEL--LALQTKLETLTNQNSDCKQH 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   944 IEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQET-------------LKKKLLDQEAK---LKKELEN 1007
Cdd:pfam10174  326 IEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLteekstlageirdLKDMLDVKERKinvLQKKIEN 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1008 TALELSQKEKQFnakmlemaqansAGISDAVSRLETNQKEQIESLTEvhrreLNDVISIWEKKLnqqaEELQEIHEIQLQ 1087
Cdd:pfam10174  406 LQEQLRDKDKQL------------AGLKERVKSLQTDSSNTDTALTT-----LEEALSEKERII----ERLKEQREREDR 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1088 EKEQEVAELKQkillfgcEKEEMNKEITWLKEEGVKQDTTLNELQEqlkqksaHVNSLAQDETKLKAHLEKLEVDLNKSL 1167
Cdd:pfam10174  465 ERLEELESLKK-------ENKDLKEKVSALQPELTEKESSLIDLKE-------HASSLASSGLKKDSKLKSLEIAVEQKK 530

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 578805993  1168 KENTFLQEQLVELKMlAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1220
Cdd:pfam10174  531 EECSKLENQLKKAHN-AEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVE 582
PRK12704 PRK12704
phosphodiesterase; Provisional
 369-508 4.69e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  369 RDAKNLIEQLEQDKGMVIAETKRQMHEtleMKEEEIAQLRSRIKQMTTQGE-ELRE------QKEKSERAAFEELEKALS 441
Cdd:PRK12704   27 KIAEAKIKEAEEEAKRILEEAKKEAEA---IKKEALLEAKEEIHKLRNEFEkELRErrnelqKLEKRLLQKEENLDRKLE 103

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578805993  442 TAQKTEEARRKLKAEMDEQIKTIEKTSEE-ERISLQQ--ELSRV--------KQEVVDVMKKSSEEQIAKLQKLHEKE 508
Cdd:PRK12704  104 LLEKREEELEKKEKELEQKQQELEKKEEElEELIEEQlqELERIsgltaeeaKEILLEKVEEEARHEAAVLIKEIEEE 181
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 304-898 4.94e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 4.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   304 LQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKG 383
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   384 MVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELR--EQKEKSERAAFEELEKALSTAQKTEEARrkLKAEMDEQI 461
Cdd:pfam12128  326 ALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKalTGKHQDVTAKYNRRRSKIKEQNNRDIAG--IKDKLAKIR 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   462 KTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEqmkvALEKSQSE 541
Cdd:pfam12128  404 EARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDE----RIERAREE 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   542 ylkisQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSL------------------EKSLQEN 603
Cdd:pfam12128  480 -----QEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqagtllhflrkeapdwEQSIGKV 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   604 KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLK----- 678
Cdd:pfam12128  555 ISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQangel 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   679 ---DKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKA-----RHKLEEELSVLKDQTDKMKQELEAKMDE--- 747
Cdd:pfam12128  635 ekaSREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDsanerLNSLEAQLKQLDKKHQAWLEEQKEQKREart 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   748 QKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN-QLELLLKERDKHLK----------EHQAHVENLEADIKRSEGElQQA 816
Cdd:pfam12128  715 EKQAYWQVVEGALDAQLALLKAAIAARRSGAKaELKALETWYKRDLAslgvdpdviaKLKREIRTLERKIERIAVR-RQE 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   817 SAKLDVFQSYQSATHEQTKAYEeqlaqLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 896
Cdd:pfam12128  794 VLRYFDWYQETWLQRRPRLATQ-----LSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCE 868


                   ..
gi 578805993   897 ME 898
Cdd:pfam12128  869 MS 870
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 510-1345 4.96e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 4.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   510 ARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKIsqEKEQQESLALEELELQKKAiLTESENKLRDLQQEAETYRTRI 589
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRR--EREKAERYQALLKEKREYE-GYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   590 LELESSLEKS---LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALwtEKLQVLKQQYQTEMEKLR 666
Cdd:TIGR02169  247 ASLEEELEKLteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   667 EKCEQEKETLLKDKEIIfqahieemnEKTLEKLDVKqteleslsselsevlkaRHKLEEELSVLKDQTDKMKQELEAKMD 746
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEEL---------EREIEEERKR-----------------RDKLTEEYAELKEELEDLRAELEEVDK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   747 EQKNHHQQQVDSIIKEHEVSIQRTEkaLKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 826
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINE--LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   827 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVqdlmQQLEKQNSEMEQKVKSLTQ 906
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE----EVLKASIQGVHGTVAQLGS 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   907 V---YESKLE--DGNKEQE---QTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNE---------EYETKF 969
Cdd:TIGR02169  533 VgerYATAIEvaAGNRLNNvvvEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGvigfavdlvEFDPKY 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   970 KNQEKK-------MEKVKQKAKEMQE----TLKKKLLDQE------AKLKKELENTALELSQKEKQFNAKMLEMaQANSA 1032
Cdd:TIGR02169  613 EPAFKYvfgdtlvVEDIEAARRLMGKyrmvTLEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGL-KRELS 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1033 GISDAVSRLETNQKEQIESLTEVHR--RELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQkillfgcEKEEM 1110
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSDASRkiGEIEKEIEQLEQEEEKLKERLEEL-EEDLSSLEQEIENVKS-------ELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1111 NKEITWLKEEGVKQDTTLNEL-----QEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAE 1185
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1186 EDKRKVSELTSK---LKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEA--KTNELINISS 1260
Cdd:TIGR02169  844 DLKEQIKSIEKEienLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQieKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1261 SKTNAILSRISHCQhrtTKVKEALLIKTCTVSE--LEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVT 1338
Cdd:TIGR02169  924 AKLEALEEELSEIE---DPKGEDEEIPEEELSLedVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE 1000


                   ....*..
gi 578805993  1339 EKEALQK 1345
Cdd:TIGR02169 1001 ERKAILE 1007
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 332-603 4.99e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.34  E-value: 4.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  332 LTSEK-EALQEQLDERLQELEKIKdlhmaeKTKLITQ-LRDAKNLIEQLEQDKGMViaETKRQMHETLEMKEEEIaQLRS 409
Cdd:PTZ00108 1099 LTKEKvEKLNAELEKKEKELEKLK------NTTPKDMwLEDLDKFEEALEEQEEVE--EKEIAKEQRLKSKTKGK-ASKL 1169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  410 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEqiKTIEKTSEEERISLQQELSRVKQEVVDV 489
Cdd:PTZ00108 1170 RKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSN--SSGSDQEDDEEQKTKPKKSSVKRLKSKK 1247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  490 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ------SEYLKISQEKEQQESLALEELELQ 563
Cdd:PTZ00108 1248 NNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNggskpsSPTKKKVKKRLEGSLAALKKKKKS 1327

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 578805993  564 KKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQEN 603
Cdd:PTZ00108 1328 EKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSED 1367
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1939-2115 5.03e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 5.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1939 SNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH---------QQELEILKkEYDQEREEkIKQEQEDLELK 2009
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglvdlseeaKLLLQQLS-ELESQLAE-ARAELAEAEAR 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2010 HNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQ---LLKKIAEKDDDLKRTAKRYEEILDAR 2086
Cdd:COG3206   242 LAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDviaLRAQIAALRAQLQQEAQRILASLEAE 321

                         170       180       190
                  ....*....|....*....|....*....|.
gi 578805993 2087 EEEMTAKVRDLQTQLEELQKKYQQ--KLEQE 2115
Cdd:COG3206   322 LEALQAREASLQAQLAQLEARLAElpELEAE 352
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 328-1098 5.18e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 5.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   328 QCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLiTQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL 407
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKK-KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   408 RSRIKQMTTQGEELREQKEKSERAafEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQElsrvkqevv 487
Cdd:TIGR00618  232 REALQQTQQSHAYLTQKREAQEEQ--LKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIK--------- 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   488 dvmkksSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVAlEKSQSEYLKISQEKEQQESLALEELELQKKAI 567
Cdd:TIGR00618  301 ------AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIE-EQRRLLQTLHSQEIHIRDAHEVATSIREISCQ 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   568 LTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLkHQQDALW 647
Cdd:TIGR00618  374 QHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAA-AITCTAQ 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   648 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNE-KTLEKLDVKQTELESLSSELSEVLKARHKLEEE 726
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLElQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQR 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   727 LSVLKDQTDKMKQELEAKMDEQKNHHQqqvdsIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 806
Cdd:TIGR00618  533 GEQTYAQLETSEEDVYHQLTSERKQRA-----SLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   807 KRSEGELQQASAKLDVFQS-YQSATHEQTKAYEEQLAqlqqklldleteriLLTKQVAEVEAQKKDVCTELDAHKIQVQD 885
Cdd:TIGR00618  608 DMLACEQHALLRKLQPEQDlQDVRLHLQQCSQELALK--------------LTALHALQLTLTQERVREHALSIRVLPKE 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   886 LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTkqilvEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEY 965
Cdd:TIGR00618  674 LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELE-----THIEEYDREFNEIENASSSLGSDLAAREDALNQSLKEL 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   966 ETKFKNQEKKMEKVKQKAKEmQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQ 1045
Cdd:TIGR00618  749 MHQARTVLKARTEAHFNNNE-EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLV 827

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 578805993  1046 KEQIESLTEVHRR-----ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1098
Cdd:TIGR00618  828 QEEEQFLSRLEEKsatlgEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1982-2125 5.27e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 5.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1982 QELEILKKEYDQEREE--KIKQEQEDLELKhnstLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEEtn 2059
Cdd:PRK00409  523 ASLEELERELEQKAEEaeALLKEAEKLKEE----LEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQL-- 596

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2060 QLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDlQTQLEELQK----KYQQKLEQEENPGNDNVTI 2125
Cdd:PRK00409  597 QKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEK-QEELKVGDEvkylSLGQKGEVLSIPDDKEAIV 665
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 494-872 5.39e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 5.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   494 SEEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEqMKVALEKSQSEYLKISQEKEQqeslaLEELELQKKAILTES 571
Cdd:TIGR02169  669 SRSEPAELQRLRERleGLKRELSSLQSELRRIENRLDE-LSQELSDASRKIGEIEKEIEQ-----LEQEEEKLKERLEEL 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   572 ENKLRDLQQEAETYRTRILELESSLEKsLQENKNQSKDLAVHLEAEKNKHN-KEITVMVEKHKTELESLKHQQDAL--WT 648
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIeqKL 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   649 EKLQVLKQQYQTEMEKLrekceQEKETLLKDKEIIFQAHIEEMN---EKTLEKLDVKQTELESLSSELSEVLKARHKLEE 725
Cdd:TIGR02169  822 NRLTLEKEYLEKEIQEL-----QEQRIDLKEQIKSIEKEIENLNgkkEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   726 ELSVLKDQtdkmKQELEAKMDEQKNHHQQQvdsiikehevsiQRTEKALKDQINQLELLLKErDKHLKEHQAHVENLEAD 805
Cdd:TIGR02169  897 QLRELERK----IEELEAQIEKKRKRLSEL------------KAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAE 959

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578805993   806 IKRSEGELQQasakldvFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDV 872
Cdd:TIGR02169  960 LQRVEEEIRA-------LEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1636-1910 5.43e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 5.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1636 KSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKL 1715
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1716 KSVESS---QSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYeekisvlQRNLTEKEKLLQRVGQEKEEtvSSHFEMRCQ 1792
Cdd:pfam17380  370 IAMEISrmrELERLQMERQQKNERVRQELEAARKVKILEEER-------QRKIQQQKVEMEQIRAEQEE--ARQREVRRL 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1793 YQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNniQAKQNLENVFDDVQKTLQEKELTCQIL 1872
Cdd:pfam17380  441 EEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEE--QRRKILEKELEERKQAMIEEERKRKLL 518

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 578805993  1873 EQKIKELDSCLVRQKEVHRVEMEELTSK--YEKLQALQQM 1910
Cdd:pfam17380  519 EKEMEERQKAIYEEERRREAEEERRKQQemEERRRIQEQM 558
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 439-617 6.49e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 6.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  439 ALSTAQKTEEARRKLKAEMDEQIKTIEKTsEEERISLQQELSRVKQEVVDVMKK--SSEEQIAKLQKlHEKELARKEQEL 516
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAAL-KKEEKALLKQLAALERRIAALARRirALEQELAALEA-ELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  517 TKKLQTREREFQEQMKVALEKSQSEYLKI---------------------------------SQEKEQQESLALEELELQ 563
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALllspedfldavrrlqylkylaparreqaeelraDLAELAALRAELEAERAE 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  564 KKAILTESENKLRDLQQEAETYRTRILELESSLEK------SLQENKNQSKDLAVHLEAE 617
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAElaaelaELQQEAEELEALIARLEAE 235
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1591-1719 6.67e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 6.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1591 ELGEEKDnrvkEAEEKILTLENQvysmKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAA 1670
Cdd:PRK00409  510 LIGEDKE----KLNELIASLEEL----ERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKE 581

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 578805993 1671 IKK---QLLSQMEEKEEQYKKGTESH-----LSELNTKLQEREREVHILEEKLKSVE 1719
Cdd:PRK00409  582 AKKeadEIIKELRQLQKGGYASVKAHelieaRKRLNKANEKKEKKKKKQKEKQEELK 638
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 272-504 6.68e-03

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 41.57  E-value: 6.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   272 EPQAEVFTKEENPESDGEPVVEDGTS-VKTLETLQQRVKRQEnLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERlqel 350
Cdd:pfam10168  477 PPSPPLLCSKEDVTVDEPLRGLQEDSfEDHIKSILQRSVSNP-ILSADKLSSPSPQECLQLLSRATQVFREEYLKK---- 551

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   351 ekiKDLHMAEKTKLITQLRDAKnliEQLEQDKGMVIAETK--RQMHETLEMKEEEIAQ----LRSRIKQMTTQGEELREQ 424
Cdd:pfam10168  552 ---HDLAREEIQKRVKLLKLQK---EQQLQELQSLEEERKslSERAEKLAEKYEEIKDkqekLMRRCKKVLQRLNSQLPV 625

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993   425 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER---ISLQQELSRVKQEVVDVMKKSSEEQIAKL 501
Cdd:pfam10168  626 LSDAEREMKKELETINEQLKHLANAIKQAKKKMNYQRYQIAKSQSIRKkssLSLSEKQRKTIKEILKQLGSEIDELIKQV 705


                   ...
gi 578805993   502 QKL 504
Cdd:pfam10168  706 KDI 708
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 862-980 6.79e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 6.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  862 VAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKE-QEQTKQILVEKENMILQMREGQ 940
Cdd:PRK00409  522 IASLEELER----ELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEaQQAIKEAKKEADEIIKELRQLQ 597

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 578805993  941 KKEI-EILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVK 980
Cdd:PRK00409  598 KGGYaSVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELK 638
mukB PRK04863
chromosome partition protein MukB;
192-510 6.84e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.87  E-value: 6.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  192 EQLIQRLRRMERSLSSYRGKYSEELQMDQQAKKHLQ--------------EEFDASLEEKDQYISVLQTQVSLLKQrlrN 257
Cdd:PRK04863  840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSalnrllprlnlladETLADRVEEIREQLDEAEEAKRFVQQ---H 916

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  258 GpmnvdvlKPLPQLEPQAEVFtkeENPESDGEPVVEDgtsVKTLETLQQRVKRQENLLkrcKETIQSHK----EQCTLLT 333
Cdd:PRK04863  917 G-------NALAQLEPIVSVL---QSDPEQFEQLKQD---YQQAQQTQRDAKQQAFAL---TEVVQRRAhfsyEDAAEML 980

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  334 SEKEALQEQLDERLQELEkikdlhmAEKTKLITQLRDAKNLIEQLEQdkgmVIAETKrqmhETLEMKEEEIAQLRSRIKQ 413
Cdd:PRK04863  981 AKNSDLNEKLRQRLEQAE-------QERTRAREQLRQAQAQLAQYNQ----VLASLK----SSYDAKRQMLQELKQELQD 1045

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  414 MTTQGEELREQKEKSERaafEELEKALSTAQ----KTEEARRKLKAEMDEQIKTIEKtseEERISLQQELSRVKQEV--V 487
Cdd:PRK04863 1046 LGVPADSGAEERARARR---DELHARLSANRsrrnQLEKQLTFCEAEMDNLTKKLRK---LERDYHEMREQVVNAKAgwC 1119

                         330       340
                  ....*....|....*....|...
gi 578805993  488 DVMKKSSEEQIAKlqKLHEKELA 510
Cdd:PRK04863 1120 AVLRLVKDNGVER--RLHRRELA 1140
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1291-1472 6.91e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 6.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1291 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK----- 1365
Cdd:COG3883    32 LEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDvllgs 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1366 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQnsiSLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLS 1445
Cdd:COG3883   112 ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKA---ELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLS 188

                         170       180
                  ....*....|....*....|....*..
gi 578805993 1446 KEKISALEQVDDWSNKFSEWKKKAQSR 1472
Cdd:COG3883   189 AEEAAAEAQLAELEAELAAAEAAAAAA 215
PRK12704 PRK12704
phosphodiesterase; Provisional
 1959-2090 7.01e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 7.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1959 KQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNtQLAQKEQELEMtike 2038
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 578805993 2039 tinkaqevEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM 2090
Cdd:PRK12704  101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
COG5022 COG5022
Myosin heavy chain [General function prediction only];
310-812 7.49e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.60  E-value: 7.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  310 RQENLLKRCKETIQSHKEQCTLltsEKEALQEQLDERLQELEK-IKDLHMAEKTklITQLrdaKNLIEQLEQDKGMVIAE 388
Cdd:COG5022   843 KAEVLIQKFGRSLKAKKRFSLL---KKETIYLQSAQRVELAERqLQELKIDVKS--ISSL---KLVNLELESEIIELKKS 914

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  389 TKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EEARRKLKAEMDEQIKTIEKT 467
Cdd:COG5022   915 LSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEyEDLLKKSTILVREGNKANSEL 994

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  468 S---------EEERISLQQELSRVKQEVVDVMKKSSEEQI--------------AKLQKLHEKELARKEQELTKKLQTRE 524
Cdd:COG5022   995 KnfkkelaelSKQYGALQESTKQLKELPVEVAELQSASKIissestelsilkplQKLKGLLLLENNQLQARYKALKLRRE 1074

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  525 REFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK 604
Cdd:COG5022  1075 NSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQL 1154

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  605 ---------------------NQSKDLAVHLEAEKNKhNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME 663
Cdd:COG5022  1155 eldglfweanlealpspppfaALSEKRLYQSALYDEK-SKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVP 1233

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  664 KLREKCEQEKEtllkDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMK-QELE 742
Cdd:COG5022  1234 TEYSTSLKGFN----NLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKaSSLR 1309

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  743 AKMDEQKNHHQQQVDSIIKEHEVS-----------IQRTEKALKDQINQLELLLKERDKHLkehQAHVENLEADIKRSEG 811
Cdd:COG5022  1310 WKSATEVNYNSEELDDWCREFEISdvdeeleeliqAVKVLQLLKDDLNKLDELLDACYSLN---PAEIQNLKSRYDPADK 1386


                  .
gi 578805993  812 E 812
Cdd:COG5022  1387 E 1387
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1426-2103 7.64e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 7.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1426 EKCELLDQVQDLSFKVDTLS---------KEKISALEQVDDWSNKFSE-WKKKAQSRFTQHQNTVKELQIQLELKSKEAY 1495
Cdd:COG4913   219 EEPDTFEAADALVEHFDDLErahealedaREQIELLEPIRELAERYAAaRERLAELEYLRAALRLWFAQRRLELLEAELE 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1496 EKDEQINLLKEELDQQnkrfdclkgemEDDKSKMEKKESNLETELKSQ-TARIMELEDHITQKTIEIESLNEVLKNYNQQ 1574
Cdd:COG4913   299 ELRAELARLEAELERL-----------EARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1575 KDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEhvnlsvkSKEEELKALEDRlESESA 1654
Cdd:COG4913   368 LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELR-------ELEAEIASLERR-KSNIP 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1655 AKLAELKRKAEQKIAAIKKQL-----LSQMEEKEEQYKKGTE--------------SHLSELNTKLQEREREVHILEEKL 1715
Cdd:COG4913   440 ARLLALRDALAEALGLDEAELpfvgeLIEVRPEEERWRGAIErvlggfaltllvppEHYAAALRWVNRLHLRGRLVYERV 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1716 KSVESSQSETLIVPRS--------AKNVAAYTEQEEADSQG--CVqktyeEKISVLQRNltekEKLLQRVGQEKEEtvSS 1785
Cdd:COG4913   520 RTGLPDPERPRLDPDSlagkldfkPHPFRAWLEAELGRRFDyvCV-----DSPEELRRH----PRAITRAGQVKGN--GT 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1786 HFEM--RCQYQERLI-------KLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHvekeggknniQAKQNLENVFD 1856
Cdd:COG4913   589 RHEKddRRRIRSRYVlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQERR----------EALQRLAEYSW 658

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1857 DVQKTLQekeltcqiLEQKIKELDSclvrqkevhrvEMEELTSKYEKLQALQQmdgrnkptelleenteekskshlvqpk 1936
Cdd:COG4913   659 DEIDVAS--------AEREIAELEA-----------ELERLDASSDDLAALEE--------------------------- 692

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1937 LLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQE-QEDLELKHNSTLK 2015
Cdd:COG4913   693 QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAlGDAVERELRENLE 772

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2016 QLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLES--HQEETNQLLKKIaeKDDDLKRtakRYEEILDAREEEMTAK 2093
Cdd:COG4913   773 ERIDALRARLNRAEEELERAMRAFNREWPAETADLDADleSLPEYLALLDRL--EEDGLPE---YEERFKELLNENSIEF 847

                         730
                  ....*....|
gi 578805993 2094 VRDLQTQLEE 2103
Cdd:COG4913   848 VADLLSKLRR 857
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1968-2166 8.22e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 8.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 1968 RLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKhnsTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVE 2047
Cdd:COG4717    50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYA---ELQEELEELEEELEELEAELEELREELEKLEKLLQ 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993 2048 AELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTimE 2127
Cdd:COG4717   127 LLPLYQELEALEAELAELPERLEELEERLEELRE-LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE--E 203

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 578805993 2128 LQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKN 2166
Cdd:COG4717   204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE 242
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1938-2171 8.65e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 8.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  1938 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKE---------HQQELEILKKEYDQEREEKIKQEQEDLEL 2008
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKikdlgeeeqLRVKEKIGELEAEIASLERSIAEKERELE 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2009 KHNSTLKQLMREFNTQLAQKEqELEMTIKETINKAQEVEAELLEShQEETNQLLKKIAEKDDDLKRTakrYEEILDARE- 2087
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIE-ELEREIEEERKRRDKLTEEYAEL-KEELEDLRAELEEVDKEFAET---RDELKDYREk 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  2088 -EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDsKLKEQEfrEQIHNLEDRLKKYEKN 2166
Cdd:TIGR02169  394 lEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL-EIKKQE--WKLEQLAADLSKYEQE 470


                   ....*
gi 578805993  2167 VYATT 2171
Cdd:TIGR02169  471 LYDLK 475
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
419-821 9.10e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 9.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  419 EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDE--QIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEE 496
Cdd:COG4717    49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEyaELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  497 QIAKLQKLHEKELARKEQELtKKLQTREREFQEqmkvaLEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLR 576
Cdd:COG4717   129 PLYQELEALEAELAELPERL-EELEERLEELRE-----LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  577 DLQQEAETYRTRILELESSLEkSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA----------- 645
Cdd:COG4717   203 ELQQRLAELEEELEEAQEELE-ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSliltiagvlfl 281

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  646 ---------LWTEKLQVLKQQYQTEMEKLREK---CEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL 713
Cdd:COG4717   282 vlgllallfLLLAREKASLGKEAEELQALPALeelEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578805993  714 SEVLKARHKLEEELSVLKDQTD--------KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLL 785
Cdd:COG4717   362 ELQLEELEQEIAALLAEAGVEDeeelraalEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEEL 441

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 578805993  786 KERDKHLKEHQAHVENLEADIKR--SEGELQQASAKLD 821
Cdd:COG4717   442 EELEEELEELREELAELEAELEQleEDGELAELLQELE 479
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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