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Conserved domains on  [gi|578821736|ref|XP_006718752|]
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N-alpha-acetyltransferase 40 isoform X3 [Homo sapiens]

Protein Classification

N-acetyltransferase( domain architecture ID 1000386)

N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate; similar to Drosophila melanogaster arylalkylamine N-acetyltransferase 1 that catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin, and octopamine

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RimI super family cl33885
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 117-169 2.98e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG0456:

Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 38.48  E-value: 2.98e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 578821736 117 RRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFrEALQFEIDDSSP 169
Cdd:COG0456   26 RGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALY-EKLGFEEVGERP 77
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 117-169 2.98e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 38.48  E-value: 2.98e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 578821736 117 RRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFrEALQFEIDDSSP 169
Cdd:COG0456   26 RGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALY-EKLGFEEVGERP 77
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 117-158 2.66e-03

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 36.34  E-value: 2.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 578821736  117 RRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFRE 158
Cdd:pfam00583  72 RGKGIGTALLQALLEWARERGCERIFLEVAADNLAAIALYEK 113
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 117-169 2.98e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 38.48  E-value: 2.98e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 578821736 117 RRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFrEALQFEIDDSSP 169
Cdd:COG0456   26 RGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALY-EKLGFEEVGERP 77
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 117-158 2.66e-03

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 36.34  E-value: 2.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 578821736  117 RRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFRE 158
Cdd:pfam00583  72 RGKGIGTALLQALLEWARERGCERIFLEVAADNLAAIALYEK 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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