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Conserved domains on  [gi|578828322|ref|XP_006721028|]
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voltage-dependent T-type calcium channel subunit alpha-1H isoform X5 [Homo sapiens]

Protein Classification

ion transporter( domain architecture ID 11997982)

ion transporter such as a voltage-gated cation channel, which enables the selective translocation of cations such as sodium, calcium, or potassium across cell membranes

CATH:  1.10.287.70
Gene Ontology:  GO:0034220|GO:0005216|GO:0005886|GO:0034702
PubMed:  15816170
TCDB:  1.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 792-1019 2.33e-65

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 222.14  E-value: 2.33e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   792 SKYFSRGIMMAILVNTLSMGVEYHEQPEE-LTNALEISNIVFTSMFALEMLLKLLACGP-LGYIRNPYNIFDGIIVVISV 869
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   870 WEIV---GQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSlktD 946
Cdd:pfam00520   81 ISLVlssVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLK---T 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578828322   947 TGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSS-WAALYFVALMTFGNYVLFNLLVAILVEGFQ 1019
Cdd:pfam00520  158 WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEfWAYIYFVSFIILGGFLLLNLFIAVIIDNFQ 231
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1293-1565 8.85e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 197.49  E-value: 8.85e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1293 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERvFLSVSNYIFTAIFVAEMMVKVVALGLLsgeHAYLQSSWNLLDGLLV 1372
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTT-VLEILDYVFTGIFTLEMLLKIIAAGFK---KRYFRSPWNILDFVVV 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1373 LVSLVDIVVAMASAGGA-------------KIlgvlrvlrllrtlrplrvISRAPGLKLVVETLISSLRPIGNIVLICCA 1439
Cdd:pfam00520   77 LPSLISLVLSSVGSLSGlrvlrllrllrllRL------------------IRRLEGLRTLVNSLIRSLKSLGNLLLLLLL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1440 FFIIFGILGVQLFKGKFYYCEGPDTRNistkaqcraahyrwvrrkYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGv 1519
Cdd:pfam00520  139 FLFIFAIIGYQLFGGKLKTWENPDNGR------------------TNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG- 199

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 578828322  1520 dqqpvqnhNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1565
Cdd:pfam00520  200 --------EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1610-1841 8.75e-52

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 183.24  E-value: 8.75e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1610 SHYLDLFITFIICVNVITMSMEHYNQPKS-LDEALKYCNYVFTIVFVFEAALKLVAFGF-RRFFKDRWNQLDLAIVLLSL 1687
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1688 MGITLEEIEmsaalpiNPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGR 1767
Cdd:pfam00520   81 ISLVLSSVG-------SLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGG 153

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578828322  1768 LECSEDNPCEGlsrHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSredkhclsylPALSPVYFVTFVLVA 1841
Cdd:pfam00520  154 KLKTWENPDNG---RTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG----------EFWAYIYFVSFIILG 214
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 99-430 1.18e-44

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 162.82  E-value: 1.18e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322    99 NPWFEHVSMLVIMLNCVTLGMFRPCEDVECgseRCNILEAFDAFIFAFFAVEMVIKMVALGLFgqKCYLGDTWNRLDFFI 178
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEP---LTTVLEILDYVFTGIFTLEMLLKIIAAGFK--KRYFRSPWNILDFVV 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   179 VVAGMMEYSLDGHN--VSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFfvffifgivgvqlwagll 256
Cdd:pfam00520   76 VLPSLISLVLSSVGslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLL------------------ 137

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   257 rnrCFLdsafvrnnnltflrpyyqteegeenpFICSSrrdNGMQkcshipgrreLRMPCTLGWEaytqpqaegvgaarna 336
Cdd:pfam00520  138 ---LFL--------------------------FIFAI---IGYQ----------LFGGKLKTWE---------------- 159

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   337 cinwnqyynvcrsgdsNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA-HSFYNFIYFILLIIVGSFFMINLCL 415
Cdd:pfam00520  160 ----------------NPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGkGEFWAYIYFVSFIILGGFLLLNLFI 223

                          330
                   ....*....|....*
gi 578828322   416 VVIATQFSETKQRES 430
Cdd:pfam00520  224 AVIIDNFQELTERTE 238
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 1879-2335 1.91e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.42  E-value: 1.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1879 AQGPGSARRVDADRPP---------LPQESPGARDAPNLVARKVSVSRMLS---------LPNDSYMFRP--VVPASAPH 1938
Cdd:PHA03247 2495 APDPGGGGPPDPDAPPapsrlapaiLPDEPVGEPVHPRMLTWIRGLEELASddagdppppLPPAAPPAAPdrSVPPPRPA 2574

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1939 PRPLQ-EVEMETYGAGTPLEScASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDT 2017
Cdd:PHA03247 2575 PRPSEpAVTSRARRPDAPPQS-ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPR 2653

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2018 LDPAEPGEKTPVRPVTQGGSLQ--SPPRSPRPASVRTrkhTFGQRCVSSRPAAPGGEEAEASDPADEEV--------SHI 2087
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQasSPPQRPRRRAARP---TVGSLTSLADPPPPPPTPEPAPHALVSATplppgpaaARQ 2730

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2088 TSSACPWQPtAEPHGPEASPVAGGERDLRRLYSVDAqgfldkPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGARRK 2167
Cdd:PHA03247 2731 ASPALPAAP-APPAVPAGPATPGGPARPARPPTTAG------PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2168 KkmSPPCISVEPPAEDE-GSARPSAAEGGSTTLRRRTPSCEATPHRDSLePTEGSGAGGDPAAKGERWGQASC------- 2239
Cdd:PHA03247 2804 P--ADPPAAVLAPAAALpPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRPPSRSPAAkpaapar 2880

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2240 -RAEHLTVPSFAFEPLDLGVPSGDPfldgSHSVTPESRASSsgaivplEPPESEPPMPVGDPPEKRRGLyltvPQCPLEK 2318
Cdd:PHA03247 2881 pPVRRLARPAVSRSTESFALPPDQP----ERPPQPQAPPPP-------QPQPQPPPPPQPQPPPPPPPR----PQPPLAP 2945

                         490
                  ....*....|....*..
gi 578828322 2319 PGSPSATPAPGGGADDP 2335
Cdd:PHA03247 2946 TTDPAGAGEPSGAVPQP 2962
 
Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 792-1019 2.33e-65

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 222.14  E-value: 2.33e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   792 SKYFSRGIMMAILVNTLSMGVEYHEQPEE-LTNALEISNIVFTSMFALEMLLKLLACGP-LGYIRNPYNIFDGIIVVISV 869
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   870 WEIV---GQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSlktD 946
Cdd:pfam00520   81 ISLVlssVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLK---T 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578828322   947 TGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSS-WAALYFVALMTFGNYVLFNLLVAILVEGFQ 1019
Cdd:pfam00520  158 WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEfWAYIYFVSFIILGGFLLLNLFIAVIIDNFQ 231
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1293-1565 8.85e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 197.49  E-value: 8.85e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1293 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERvFLSVSNYIFTAIFVAEMMVKVVALGLLsgeHAYLQSSWNLLDGLLV 1372
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTT-VLEILDYVFTGIFTLEMLLKIIAAGFK---KRYFRSPWNILDFVVV 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1373 LVSLVDIVVAMASAGGA-------------KIlgvlrvlrllrtlrplrvISRAPGLKLVVETLISSLRPIGNIVLICCA 1439
Cdd:pfam00520   77 LPSLISLVLSSVGSLSGlrvlrllrllrllRL------------------IRRLEGLRTLVNSLIRSLKSLGNLLLLLLL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1440 FFIIFGILGVQLFKGKFYYCEGPDTRNistkaqcraahyrwvrrkYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGv 1519
Cdd:pfam00520  139 FLFIFAIIGYQLFGGKLKTWENPDNGR------------------TNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG- 199

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 578828322  1520 dqqpvqnhNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1565
Cdd:pfam00520  200 --------EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1610-1841 8.75e-52

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 183.24  E-value: 8.75e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1610 SHYLDLFITFIICVNVITMSMEHYNQPKS-LDEALKYCNYVFTIVFVFEAALKLVAFGF-RRFFKDRWNQLDLAIVLLSL 1687
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1688 MGITLEEIEmsaalpiNPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGR 1767
Cdd:pfam00520   81 ISLVLSSVG-------SLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGG 153

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578828322  1768 LECSEDNPCEGlsrHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSredkhclsylPALSPVYFVTFVLVA 1841
Cdd:pfam00520  154 KLKTWENPDNG---RTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG----------EFWAYIYFVSFIILG 214
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 99-430 1.18e-44

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 162.82  E-value: 1.18e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322    99 NPWFEHVSMLVIMLNCVTLGMFRPCEDVECgseRCNILEAFDAFIFAFFAVEMVIKMVALGLFgqKCYLGDTWNRLDFFI 178
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEP---LTTVLEILDYVFTGIFTLEMLLKIIAAGFK--KRYFRSPWNILDFVV 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   179 VVAGMMEYSLDGHN--VSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFfvffifgivgvqlwagll 256
Cdd:pfam00520   76 VLPSLISLVLSSVGslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLL------------------ 137

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   257 rnrCFLdsafvrnnnltflrpyyqteegeenpFICSSrrdNGMQkcshipgrreLRMPCTLGWEaytqpqaegvgaarna 336
Cdd:pfam00520  138 ---LFL--------------------------FIFAI---IGYQ----------LFGGKLKTWE---------------- 159

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   337 cinwnqyynvcrsgdsNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA-HSFYNFIYFILLIIVGSFFMINLCL 415
Cdd:pfam00520  160 ----------------NPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGkGEFWAYIYFVSFIILGGFLLLNLFI 223

                          330
                   ....*....|....*
gi 578828322   416 VVIATQFSETKQRES 430
Cdd:pfam00520  224 AVIIDNFQELTERTE 238
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1879-2335 1.91e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.42  E-value: 1.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1879 AQGPGSARRVDADRPP---------LPQESPGARDAPNLVARKVSVSRMLS---------LPNDSYMFRP--VVPASAPH 1938
Cdd:PHA03247 2495 APDPGGGGPPDPDAPPapsrlapaiLPDEPVGEPVHPRMLTWIRGLEELASddagdppppLPPAAPPAAPdrSVPPPRPA 2574

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1939 PRPLQ-EVEMETYGAGTPLEScASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDT 2017
Cdd:PHA03247 2575 PRPSEpAVTSRARRPDAPPQS-ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPR 2653

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2018 LDPAEPGEKTPVRPVTQGGSLQ--SPPRSPRPASVRTrkhTFGQRCVSSRPAAPGGEEAEASDPADEEV--------SHI 2087
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQasSPPQRPRRRAARP---TVGSLTSLADPPPPPPTPEPAPHALVSATplppgpaaARQ 2730

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2088 TSSACPWQPtAEPHGPEASPVAGGERDLRRLYSVDAqgfldkPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGARRK 2167
Cdd:PHA03247 2731 ASPALPAAP-APPAVPAGPATPGGPARPARPPTTAG------PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2168 KkmSPPCISVEPPAEDE-GSARPSAAEGGSTTLRRRTPSCEATPHRDSLePTEGSGAGGDPAAKGERWGQASC------- 2239
Cdd:PHA03247 2804 P--ADPPAAVLAPAAALpPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRPPSRSPAAkpaapar 2880

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2240 -RAEHLTVPSFAFEPLDLGVPSGDPfldgSHSVTPESRASSsgaivplEPPESEPPMPVGDPPEKRRGLyltvPQCPLEK 2318
Cdd:PHA03247 2881 pPVRRLARPAVSRSTESFALPPDQP----ERPPQPQAPPPP-------QPQPQPPPPPQPQPPPPPPPR----PQPPLAP 2945

                         490
                  ....*....|....*..
gi 578828322 2319 PGSPSATPAPGGGADDP 2335
Cdd:PHA03247 2946 TTDPAGAGEPSGAVPQP 2962
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 2013-2169 6.37e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 44.37  E-value: 6.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2013 SPRDtlDPA----EPGEKTPVRPVTQGGSLQSPPRSPRPASVrtrkhtfgqrcvsSRPAAPGGEEAEASDPADEEVSHIT 2088
Cdd:NF040712  178 TALD--DEArwliDPDFGRPLRPLATVPRLAREPADARPEEV-------------EPAPAAEGAPATDSDPAEAGTPDDL 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2089 SSA-----CPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQW-RPSAELGSGEPGEAKAWGPEAEPAL 2162
Cdd:NF040712  243 ASArrrraGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPApAPAAPAAPAAPEAEEPARPEPPPAP 322


                  ....*..
gi 578828322 2163 GARRKKK 2169
Cdd:NF040712  323 KPKRRRR 329
 
Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 792-1019 2.33e-65

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 222.14  E-value: 2.33e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   792 SKYFSRGIMMAILVNTLSMGVEYHEQPEE-LTNALEISNIVFTSMFALEMLLKLLACGP-LGYIRNPYNIFDGIIVVISV 869
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   870 WEIV---GQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSlktD 946
Cdd:pfam00520   81 ISLVlssVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLK---T 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578828322   947 TGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSS-WAALYFVALMTFGNYVLFNLLVAILVEGFQ 1019
Cdd:pfam00520  158 WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEfWAYIYFVSFIILGGFLLLNLFIAVIIDNFQ 231
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1293-1565 8.85e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 197.49  E-value: 8.85e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1293 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERvFLSVSNYIFTAIFVAEMMVKVVALGLLsgeHAYLQSSWNLLDGLLV 1372
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTT-VLEILDYVFTGIFTLEMLLKIIAAGFK---KRYFRSPWNILDFVVV 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1373 LVSLVDIVVAMASAGGA-------------KIlgvlrvlrllrtlrplrvISRAPGLKLVVETLISSLRPIGNIVLICCA 1439
Cdd:pfam00520   77 LPSLISLVLSSVGSLSGlrvlrllrllrllRL------------------IRRLEGLRTLVNSLIRSLKSLGNLLLLLLL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1440 FFIIFGILGVQLFKGKFYYCEGPDTRNistkaqcraahyrwvrrkYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGv 1519
Cdd:pfam00520  139 FLFIFAIIGYQLFGGKLKTWENPDNGR------------------TNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG- 199

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 578828322  1520 dqqpvqnhNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1565
Cdd:pfam00520  200 --------EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1610-1841 8.75e-52

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 183.24  E-value: 8.75e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1610 SHYLDLFITFIICVNVITMSMEHYNQPKS-LDEALKYCNYVFTIVFVFEAALKLVAFGF-RRFFKDRWNQLDLAIVLLSL 1687
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1688 MGITLEEIEmsaalpiNPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGR 1767
Cdd:pfam00520   81 ISLVLSSVG-------SLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGG 153

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578828322  1768 LECSEDNPCEGlsrHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSredkhclsylPALSPVYFVTFVLVA 1841
Cdd:pfam00520  154 KLKTWENPDNG---RTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG----------EFWAYIYFVSFIILG 214
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 99-430 1.18e-44

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 162.82  E-value: 1.18e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322    99 NPWFEHVSMLVIMLNCVTLGMFRPCEDVECgseRCNILEAFDAFIFAFFAVEMVIKMVALGLFgqKCYLGDTWNRLDFFI 178
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEP---LTTVLEILDYVFTGIFTLEMLLKIIAAGFK--KRYFRSPWNILDFVV 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   179 VVAGMMEYSLDGHN--VSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFfvffifgivgvqlwagll 256
Cdd:pfam00520   76 VLPSLISLVLSSVGslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLL------------------ 137

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   257 rnrCFLdsafvrnnnltflrpyyqteegeenpFICSSrrdNGMQkcshipgrreLRMPCTLGWEaytqpqaegvgaarna 336
Cdd:pfam00520  138 ---LFL--------------------------FIFAI---IGYQ----------LFGGKLKTWE---------------- 159

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   337 cinwnqyynvcrsgdsNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA-HSFYNFIYFILLIIVGSFFMINLCL 415
Cdd:pfam00520  160 ----------------NPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGkGEFWAYIYFVSFIILGGFLLLNLFI 223

                          330
                   ....*....|....*
gi 578828322   416 VVIATQFSETKQRES 430
Cdd:pfam00520  224 AVIIDNFQELTERTE 238
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1879-2335 1.91e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.42  E-value: 1.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1879 AQGPGSARRVDADRPP---------LPQESPGARDAPNLVARKVSVSRMLS---------LPNDSYMFRP--VVPASAPH 1938
Cdd:PHA03247 2495 APDPGGGGPPDPDAPPapsrlapaiLPDEPVGEPVHPRMLTWIRGLEELASddagdppppLPPAAPPAAPdrSVPPPRPA 2574

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1939 PRPLQ-EVEMETYGAGTPLEScASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDT 2017
Cdd:PHA03247 2575 PRPSEpAVTSRARRPDAPPQS-ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPR 2653

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2018 LDPAEPGEKTPVRPVTQGGSLQ--SPPRSPRPASVRTrkhTFGQRCVSSRPAAPGGEEAEASDPADEEV--------SHI 2087
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQasSPPQRPRRRAARP---TVGSLTSLADPPPPPPTPEPAPHALVSATplppgpaaARQ 2730

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2088 TSSACPWQPtAEPHGPEASPVAGGERDLRRLYSVDAqgfldkPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGARRK 2167
Cdd:PHA03247 2731 ASPALPAAP-APPAVPAGPATPGGPARPARPPTTAG------PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2168 KkmSPPCISVEPPAEDE-GSARPSAAEGGSTTLRRRTPSCEATPHRDSLePTEGSGAGGDPAAKGERWGQASC------- 2239
Cdd:PHA03247 2804 P--ADPPAAVLAPAAALpPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRPPSRSPAAkpaapar 2880

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2240 -RAEHLTVPSFAFEPLDLGVPSGDPfldgSHSVTPESRASSsgaivplEPPESEPPMPVGDPPEKRRGLyltvPQCPLEK 2318
Cdd:PHA03247 2881 pPVRRLARPAVSRSTESFALPPDQP----ERPPQPQAPPPP-------QPQPQPPPPPQPQPPPPPPPR----PQPPLAP 2945

                         490
                  ....*....|....*..
gi 578828322 2319 PGSPSATPAPGGGADDP 2335
Cdd:PHA03247 2946 TTDPAGAGEPSGAVPQP 2962
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1929-2263 5.40e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.11  E-value: 5.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1929 RPVVPASAPHPRPLQEVEMETYGAGTPLESCASLQIPLAVSSPARSGEPlhalSPRGTARSPSLSrllcrQEAVHTdsle 2008
Cdd:PHA03307  119 PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAA----SSRQAALPLSSP-----EETARA---- 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2009 gkIDSPRDTLDPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPG----GEEAEASDPADEEV 2084
Cdd:PHA03307  186 --PSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSgcgwGPENECPLPRPAPI 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2085 SHITS--SACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAELG------SGEPGEAKAWGP 2156
Cdd:PHA03307  264 TLPTRiwEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSssstssSSESSRGAAVSP 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2157 EAEPALGARRKKKmSPPCISVEPPAEDEGSARPS--AAEGGSTTLRRRTPSC-EATPHRDSLEPTEGSGAGGDPAAKGER 2233
Cdd:PHA03307  344 GPSPSRSPSPSRP-PPPADPSSPRKRPRPSRAPSspAASAGRPTRRRARAAVaGRARRRDATGRFPAGRPRPSPLDAGAA 422

                         330       340       350
                  ....*....|....*....|....*....|
gi 578828322 2234 WGQASCRaehltvpsfafEPldLGVPSGDP 2263
Cdd:PHA03307  423 SGAFYAR-----------YP--LLTPSGEP 439
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1930-2334 2.24e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 56.72  E-value: 2.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1930 PVVPASAPHPRPLQEvEMETYGAGTPLESCASLQIPLAVSSPARSGEPLHALSPRGTARSPSlsrllcrqeavhtdsleg 2009
Cdd:PHA03307   54 TVVAGAAACDRFEPP-TGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSP------------------ 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2010 kiDSPRDTLDPAEPGEKTPVRpvtqggsLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEEVShitS 2089
Cdd:PHA03307  115 --DPPPPTPPPASPPPSPAPD-------LSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE---T 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2090 SACPWQPTAEPhgPEASPVAGGERDLRRLYSVDAQGFLD---KPGRADEQWRP-SAELGSGEPGEAKAWGPEAE-----P 2160
Cdd:PHA03307  183 ARAPSSPPAEP--PPSTPPAAASPRPPRRSSPISASASSpapAPGRSAADDAGaSSSDSSSSESSGCGWGPENEcplprP 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2161 ALGARRKKKM-----------SPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAGGDPAA 2229
Cdd:PHA03307  261 APITLPTRIWeasgwngpssrPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAA 340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2230 KGErwGQASCRAehltvpsfafepldlGVPSGDPfldGSHSVTPESRASSSGAIVPLEPPESeppmpvGDPPEKRRGLYL 2309
Cdd:PHA03307  341 VSP--GPSPSRS---------------PSPSRPP---PPADPSSPRKRPRPSRAPSSPAASA------GRPTRRRARAAV 394

                         410       420
                  ....*....|....*....|....*.
gi 578828322 2310 TVPQCPLEKPGS-PSATPAPGGGADD 2334
Cdd:PHA03307  395 AGRARRRDATGRfPAGRPRPSPLDAG 420
PKD_channel pfam08016
Polycystin cation channel; This family contains the cation channel region from group II of ...
 1648-1840 6.06e-07

Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.


Pssm-ID: 462341 [Multi-domain]  Cd Length: 225  Bit Score: 52.66  E-value: 6.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1648 YVFTIVFVFEAALKLVAFGfRRFFKDRWNQLDLAIVLLS----------------LMGITLEEIE--------------- 1696
Cdd:pfam08016   18 VVFFLYFVVEEILKIRKHR-PSYLRSVWNLLDLAIVILSvvlivlniyrdfladrLIKSVEASPVtfidfdrvaqldnly 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322  1697 -MSAALPINPTIIRIMRVLRIARVLKLLKmatgmrallDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGrlecsednp 1775
Cdd:pfam08016   97 rIILAFLVFLTWLKLFKVLRFNKTMSLFT---------KTLSRAWKDLAGFALMFVIFFFAYAQFGYLLFG--------- 158

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578828322  1776 ceglSRHATFSNFGMAFLTLFRVSTGD-NWNGImkdtlRECSRedkhclsylpALSPVYFVTFVLV 1840
Cdd:pfam08016  159 ----TQAPNFSNFVKSILTLFRTILGDfGYNEI-----FSGNR----------VLGPLLFLTFVFL 205
dnaA PRK14086
chromosomal replication initiator protein DnaA;
2017-2222 1.00e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 47.51  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2017 TLDPA--EPGEKTPVRPVTQGGSLQSPPRSP------RPASVRTRKHTFGQRCVSSRPAAPggEEAEASDPAdeevshit 2088
Cdd:PRK14086   87 TVDPSagEPAPPPPHARRTSEPELPRPGRRPyegyggPRADDRPPGLPRQDQLPTARPAYP--AYQQRPEPG-------- 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2089 ssacPWQPTAEPHGPEASPVAGGERDlrrLYSVDAQgfldkPGRADEQWRPSAelGSGEPGEAKAWGPEAEPALGARRKK 2168
Cdd:PRK14086  157 ----AWPRAADDYGWQQQRLGFPPRA---PYASPAS-----YAPEQERDREPY--DAGRPEYDQRRRDYDHPRPDWDRPR 222

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 578828322 2169 KMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSlEPTEGSG 2222
Cdd:PRK14086  223 RDRTDRPEPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQP-APAPGPG 275
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 2020-2336 2.87e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 2.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2020 PAEPGEKTPVRPVT-QGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAA-PGGEEAEASDPADEEVSHITSSACPWQPT 2097
Cdd:PRK07764  415 AAPAAAAAPAPAAApQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAqPAPAPAAAPEPTAAPAPAPPAAPAPAAAP 494

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2098 AEPHGPEASPVAGGERDLRRL--------------------------------------YSVDAQGFLDkPGRAD----- 2134
Cdd:PRK07764  495 AAPAAPAAPAGADDAATLRERwpeilaavpkrsrktwaillpeatvlgvrgdtlvlgfsTGGLARRFAS-PGNAEvlvta 573

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2135 ------EQWRPSAELGsGEPGEAKAWGPEAePALGARRKKKMSPPciSVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEA 2208
Cdd:PRK07764  574 laeelgGDWQVEAVVG-PAPGAAGGEGPPA-PASSGPPEEAARPA--APAAPAAPAAPAPAGAAAAPAEASAAPAPGVAA 649

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2209 TPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAehlTVPSFAFEPLDLGVPSGDPfLDGSHSVTPESRASSSGAIVPLEP 2288
Cdd:PRK07764  650 PEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPP---PAPAPAAPAAPAGAAPAQP-APAPAATPPAGQADDPAAQPPQAA 725

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 578828322 2289 PESEPPMPVGD-----------PPEKRRGLYLTVPQCPLEKPGSPSATPAPGGGADDPV 2336
Cdd:PRK07764  726 QGASAPSPAADdpvplppepddPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEE 784
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 1879-2238 3.00e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 3.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1879 AQGPGSARRVDADRPPlPQESPGARDAPNLVARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLES 1958
Cdd:PRK07764  409 APAPAAAAPAAAAAPA-PAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAA 487

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1959 CASLQIPLAVSSPARSGEPLHALSPRG---------TARSPSLSRLLCRQEAVHT---DSLEGKIDSPRDTLDPAEPGEK 2026
Cdd:PRK07764  488 PAPAAAPAAPAAPAAPAGADDAATLRErwpeilaavPKRSRKTWAILLPEATVLGvrgDTLVLGFSTGGLARRFASPGNA 567

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2027 TPVRPVTQ---GGSLQ-----SPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEEVSH----ITSSACPW 2094
Cdd:PRK07764  568 EVLVTALAeelGGDWQveavvGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAApaeaSAAPAPGV 647

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2095 QPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGARRkkkmsppc 2174
Cdd:PRK07764  648 AAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAA-------- 719

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578828322 2175 isvEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQAS 2238
Cdd:PRK07764  720 ---QPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2060-2254 5.78e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.25  E-value: 5.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2060 RCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLdKPGRADEQWRP 2139
Cdd:PRK12323  359 RMLAFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARR-SPAPEALAAAR 437

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2140 SAELGSGEPGEAKAWGPEAEPALGARrkkkmsPPCISVEPPAEDEGSARPSAAEGGSttlrrRTPSCEATPHRDSLEPTE 2219
Cdd:PRK12323  438 QASARGPGGAPAPAPAPAAAPAAAAR------PAAAGPRPVAAAAAAAPARAAPAAA-----PAPADDDPPPWEELPPEF 506

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 578828322 2220 GSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPL 2254
Cdd:PRK12323  507 ASPAPAQPDAAPAGWVAESIPDPATADPDDAFETL 541
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 2013-2169 6.37e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 44.37  E-value: 6.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2013 SPRDtlDPA----EPGEKTPVRPVTQGGSLQSPPRSPRPASVrtrkhtfgqrcvsSRPAAPGGEEAEASDPADEEVSHIT 2088
Cdd:NF040712  178 TALD--DEArwliDPDFGRPLRPLATVPRLAREPADARPEEV-------------EPAPAAEGAPATDSDPAEAGTPDDL 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2089 SSA-----CPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQW-RPSAELGSGEPGEAKAWGPEAEPAL 2162
Cdd:NF040712  243 ASArrrraGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPApAPAAPAAPAAPEAEEPARPEPPPAP 322


                  ....*..
gi 578828322 2163 GARRKKK 2169
Cdd:NF040712  323 KPKRRRR 329
PKD_channel pfam08016
Polycystin cation channel; This family contains the cation channel region from group II of ...
 875-1018 1.55e-03

Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.


Pssm-ID: 462341 [Multi-domain]  Cd Length: 225  Bit Score: 42.26  E-value: 1.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322   875 QADGGLSVLRTFRLLRVLKLVRFlpalRRQLVVLVKTM----DNVATFCTLLMLFIFIFSILGMHLFGCKFSlktdtgdt 950
Cdd:pfam08016   95 LYRIILAFLVFLTWLKLFKVLRF----NKTMSLFTKTLsrawKDLAGFALMFVIFFFAYAQFGYLLFGTQAP-------- 162

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578828322   951 vpdrkNFDSLLWAIVTVFQILtqedWNVVLYNGMASTSSW-AALYFVALMTFGNYVLFNLLVAILVEGF 1018
Cdd:pfam08016  163 -----NFSNFVKSILTLFRTI----LGDFGYNEIFSGNRVlGPLLFLTFVFLVIFILLNLFLAIINDSY 222
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 2020-2216 1.85e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.44  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2020 PAEPGEktPVRPVTQGGslQSPPRSPRPASVRTRkhtfgqrcvSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAE 2099
Cdd:PRK07764  615 PAAPAA--PAAPAAPAP--AGAAAAPAEASAAPA---------PGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAP 681

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2100 PHGPEASPVAGGERDLRRlYSVDAQGFLDKPGRADEQW--RPSAELGSGEPGEAKAWG----PEAEPALGARRKKKMSPP 2173
Cdd:PRK07764  682 PPAPAPAAPAAPAGAAPA-QPAPAPAATPPAGQADDPAaqPPQAAQGASAPSPAADDPvplpPEPDDPPDPAGAPAQPPP 760

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 578828322 2174 CISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLE 2216
Cdd:PRK07764  761 PPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEE 803
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2013-2204 2.19e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.33  E-value: 2.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2013 SPRDTLDPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQR--CVSSRPAAPGGEEAEASDPADEEVSHITSS 2090
Cdd:PRK12323  396 APAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGpgGAPAPAPAPAAAPAAAARPAAAGPRPVAAA 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2091 ACPWQPTAEPhGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR--PSAELGSGEPGEAKAWGPEAEPALGARRKK 2168
Cdd:PRK12323  476 AAAAPARAAP-AAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVaeSIPDPATADPDDAFETLAPAPAAAPAPRAA 554

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 578828322 2169 KMSPPCISVEPPAEDEgSARPSAAEGGSTTLRRRTP 2204
Cdd:PRK12323  555 AATEPVVAPRPPRASA-SGLPDMFDGDWPALAARLP 589
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1982-2238 2.44e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 43.30  E-value: 2.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1982 SPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKTPvRPVTQGGS--LQSPPRSPRPASVRTR--KHTF 2057
Cdd:PRK07003  366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAP-KAAAAAAAtrAEAPPAAPAPPATADRgdDAAD 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2058 GQRCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGfLDKPGRADE-- 2135
Cdd:PRK07003  445 GDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARA-PAAASREDApa 523

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2136 -QWRPSAELGSGEPGEAK--AWGPEAEPALGARRKKKMSppcISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHR 2212
Cdd:PRK07003  524 aAAPPAPEARPPTPAAAApaARAGGAAAALDVLRNAGMR---VSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPR 600

                         250       260
                  ....*....|....*....|....*.
gi 578828322 2213 DSLEPTEGSGAGGDPAAKGERWGQAS 2238
Cdd:PRK07003  601 ARAATGDAPPNGAARAEQAAESRGAP 626
PHA03309 PHA03309
transcriptional regulator ICP4; Provisional
 1958-2301 3.45e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 42.92  E-value: 3.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1958 SCASLQIPLAVSSPARSGEPLHALSP--RGTARSPS-----------------LSRLLCRQEAVHTDSLEGKidsprDTL 2018
Cdd:PHA03309 1572 SSASHDRSPSSSSRRRDGRPSSRRRPsrRMSARPPSrppaavilraswryaeeVAREMLDAAASRFDEADGE-----DPL 1646

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2019 DPAEPGEKtPVRPVT-------QGGSLQSPPRSPRPASvrtrkhtfGQRCVSSRPAApggeeaeASDPADEEVshitssa 2091
Cdd:PHA03309 1647 PPAACGGK-PIAPETlvalceqRGRGPTSLPRAPTPRS--------GEALAAPRRSG-------AKDPRQGQY------- 1703

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2092 CPWQPTAE-PHGPEASPVAggERDLRRLYSVDAQGFLD----------KPGRADEQWRPSAELGSGEPGEAKAWGPEA-E 2159
Cdd:PHA03309 1704 CPSARRSEaPHSPSPRDVA--LRLLERQQELNRQLLLElrrgsceispSPRRRDAEGRRFGCRQDDDDGYDYEGGRESpE 1781

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2160 PALGARRKKKMSPPC--------------ISV-EPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAG 2224
Cdd:PHA03309 1782 RVLGRRQSRRDSVPVrrrsgaancggrwmISAgRSSSSSSSSSSSSSSSPSSRPSRSATPSLSPSPSPPRRAPVDRSRSG 1861

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2225 -----GDPAAKGERWG-QASCRAEHL---TVPSFAFEPLDLGVPSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPM 2295
Cdd:PHA03309 1862 rrrerDRPSANPFRWApRQRSRADHSpdgTAPGDAPLNLEDGPGRGRPIWTPSSATTLPSRSGPEDSVDETETEDSAPPA 1941


                  ....*.
gi 578828322 2296 PVGDPP 2301
Cdd:PHA03309 1942 RLAPSP 1947
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1886-2301 9.16e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 9.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1886 RRVDADRPPLPQESPGARDAPNLVARKVSVSRmlslpndsymfrPVVPASAPHPRPLQEVEMETYGAGTPLESCASLQIP 1965
Cdd:PHA03247 2669 RLGRAAQASSPPQRPRRRAARPTVGSLTSLAD------------PPPPPPTPEPAPHALVSATPLPPGPAAARQASPALP 2736

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 1966 LAVSSPARSGEPLHALSPRGTARSPSLS----------------RLLCRQEAVHTDSLEGKIDSPRDTLDP--AEPGEKT 2027
Cdd:PHA03247 2737 AAPAPPAVPAGPATPGGPARPARPPTTAgppapappaapaagppRRLTRPAVASLSESRESLPSPWDPADPpaAVLAPAA 2816

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2028 PVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASdpadeevshiTSSACPWQPTAEPHgPEASP 2107
Cdd:PHA03247 2817 ALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRP----------PSRSPAAKPAAPAR-PPVRR 2885

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2108 VAggerdlRRLYSVDAQGFLDKPgraDEQWRPSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPcisVEPPAEDEGSA 2187
Cdd:PHA03247 2886 LA------RPAVSRSTESFALPP---DQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP---LAPTTDPAGAG 2953

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828322 2188 RPSAAE-----GGSTTLRRRTPSCEATPHRDSLEPTEGSGAG--GDPAAKGERWgqASCRAEHL-TVPSFAFEPLDLGVP 2259
Cdd:PHA03247 2954 EPSGAVpqpwlGALVPGRVAVPRFRVPQPAPSREAPASSTPPltGHSLSRVSSW--ASSLALHEeTDPPPVSLKQTLWPP 3031

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 578828322 2260 SGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPP 2301
Cdd:PHA03247 3032 DDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPA 3073
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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