NCBI Conserved Domain Search

Conserved domains on [gi|578837041|ref|XP_006724242|]

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calcineurin-binding protein cabin-1 isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

MEF2_binding

pfam09047

MEF2 binding; The myocyte enhancer factor-2 (MEF2) binding domain, predominantly found in the ...

2162-2196

8.71e-16

MEF2 binding; The myocyte enhancer factor-2 (MEF2) binding domain, predominantly found in the calcineurin-binding protein CABIN 1, adopts an amphipathic alpha-helical structure, which allows it to bind a hydrophobic groove on the MEF2S domain, forming a triple-helical interaction. Interaction of this domain with MEF2 causes repression of transcription.

Pssm-ID: 370261 [Multi-domain] Cd Length: 35 Bit Score: 72.58 E-value: 8.71e-16

                           10        20        30
                   ....*....|....*....|....*....|....*
gi 578837041  2162 TLLSPKGSISEETKQKLKSAILSAQSAANVRKESL 2196
Cdd:pfam09047    1 TLLSPKGSISEETKQKLKNAILSAQSAANVKKDSL 35

TPR

COG0457

Tetratricopeptide (TPR) repeat [General function prediction only];

30-205

2.36e-11

Tetratricopeptide (TPR) repeat [General function prediction only];

Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 66.18 E-value: 2.36e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   30 EAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEasllreavssgdekeglKHPGLilkYSTYKNLAQLAAQREDLETA 109
Cdd:COG0457     2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE-----------------LDPDD---AEALYNLGLAYLRLGRYEEA 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  110 MEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDC 189
Cdd:COG0457    62 LADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141

                         170
                  ....*....|....*.
gi 578837041  190 RYSKGLVLKEKIFEEQ 205
Cdd:COG0457   142 DDADALYNLGIALEKL 157

PHA03247 super family

cl33720

large tegument protein UL36; Provisional

1948-2200

1.58e-09

large tegument protein UL36; Provisional

The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 1.58e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1948 GAAAQRQASGDTPTTPKHPKDSRENFfpvtVVPTAPDPVPADSvQRPSDAHTKPRPAlaaATTIITCPPSASASTLDQSK 2027
Cdd:PHA03247 2583 TSRARRPDAPPQSARPRAPVDDRGDP----RGPAPPSPLPPDT-HAPDPPPPSPSPA---ANEPDPHPPPTVPPPERPRD 2654

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2028 DPGPPRPHRP-----EATPSMASLGPEG-------EELARVAEGTSFPPQEPRHSPQvkmAPTSSPAEPhcWPAEAALGT 2095
Cdd:PHA03247 2655 DPAPGRVSRPrrarrLGRAAQASSPPQRprrraarPTVGSLTSLADPPPPPPTPEPA---PHALVSATP--LPPGPAAAR 2729

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2096 GAEPTCSQAASSKAPSSGSAQPpeghpgkPEPSRAKSRPLPNMPklviPSAAtkfPPEITVTPPTPTLLSPKGSISEETK 2175
Cdd:PHA03247 2730 QASPALPAAPAPPAVPAGPATP-------GGPARPARPPTTAGP----PAPA---PPAAPAAGPPRRLTRPAVASLSESR 2795

                         250       260
                  ....*....|....*....|....*
gi 578837041 2176 QKLKSAILSAQSAANVRKESLCQPA 2200
Cdd:PHA03247 2796 ESLPSPWDPADPPAAVLAPAAALPP 2820

Name

Accession

Description

Interval

E-value

MEF2_binding

pfam09047

MEF2 binding; The myocyte enhancer factor-2 (MEF2) binding domain, predominantly found in the ...

2162-2196

8.71e-16

Pssm-ID: 370261 [Multi-domain] Cd Length: 35 Bit Score: 72.58 E-value: 8.71e-16

                           10        20        30
                   ....*....|....*....|....*....|....*
gi 578837041  2162 TLLSPKGSISEETKQKLKSAILSAQSAANVRKESL 2196
Cdd:pfam09047    1 TLLSPKGSISEETKQKLKNAILSAQSAANVKKDSL 35

MEF2_binding

cd13839

Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1; ...

2162-2196

5.11e-14

Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1; The myocyte enhancer factor-2 (MEF2) binding domain, as found in the calcineurin-binding protein cabin-1, adopts an amphipathic alpha-helical structure, which allows it to bind to a hydrophobic groove on the MEF2S domain, forming a triple-helical interaction. Interaction of this domain with MEF2 causes repression of transcription. Cabin-1 inhibits calcineurin-mediated signal transduction in T-cell receptor-mediated signalling pathways, by binding to the activated form of calcineurin. Cabin-1 acts as a co-repressor of MEF2, the mycocyte enhancer factor-2, which regulates transcription in a calcium-dependent manner and plays vital roles in T-cell development and function.

Pssm-ID: 260103 [Multi-domain] Cd Length: 35 Bit Score: 67.79 E-value: 5.11e-14

                          10        20        30
                  ....*....|....*....|....*....|....*
gi 578837041 2162 TLLSPKGSISEETKQKLKSAILSAQSAANVRKESL 2196
Cdd:cd13839     1 TLLSPKGSISEETKQKLKNAILSSQSAANVKKDTL 35

TPR

COG0457

Tetratricopeptide (TPR) repeat [General function prediction only];

30-205

2.36e-11

Tetratricopeptide (TPR) repeat [General function prediction only];

Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 66.18 E-value: 2.36e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   30 EAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEasllreavssgdekeglKHPGLilkYSTYKNLAQLAAQREDLETA 109
Cdd:COG0457     2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE-----------------LDPDD---AEALYNLGLAYLRLGRYEEA 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  110 MEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDC 189
Cdd:COG0457    62 LADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141

                         170
                  ....*....|....*.
gi 578837041  190 RYSKGLVLKEKIFEEQ 205
Cdd:COG0457   142 DDADALYNLGIALEKL 157

PHA03247

large tegument protein UL36; Provisional

1948-2200

1.58e-09

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 1.58e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1948 GAAAQRQASGDTPTTPKHPKDSRENFfpvtVVPTAPDPVPADSvQRPSDAHTKPRPAlaaATTIITCPPSASASTLDQSK 2027
Cdd:PHA03247 2583 TSRARRPDAPPQSARPRAPVDDRGDP----RGPAPPSPLPPDT-HAPDPPPPSPSPA---ANEPDPHPPPTVPPPERPRD 2654

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2028 DPGPPRPHRP-----EATPSMASLGPEG-------EELARVAEGTSFPPQEPRHSPQvkmAPTSSPAEPhcWPAEAALGT 2095
Cdd:PHA03247 2655 DPAPGRVSRPrrarrLGRAAQASSPPQRprrraarPTVGSLTSLADPPPPPPTPEPA---PHALVSATP--LPPGPAAAR 2729

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2096 GAEPTCSQAASSKAPSSGSAQPpeghpgkPEPSRAKSRPLPNMPklviPSAAtkfPPEITVTPPTPTLLSPKGSISEETK 2175
Cdd:PHA03247 2730 QASPALPAAPAPPAVPAGPATP-------GGPARPARPPTTAGP----PAPA---PPAAPAAGPPRRLTRPAVASLSESR 2795

                         250       260
                  ....*....|....*....|....*
gi 578837041 2176 QKLKSAILSAQSAANVRKESLCQPA 2200
Cdd:PHA03247 2796 ESLPSPWDPADPPAAVLAPAAALPP 2820

Herpes_BLLF1

pfam05109

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...

1925-2189

2.63e-08

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.

Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 59.54 E-value: 2.63e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  1925 HLPVKVDEEAALEQAVKFCQVHLGAAAQrQASGDTPTTPK-HPKDS-RENFFPVTVVPTAPDPVPADSVQRPSDAHTKPR 2002
Cdd:pfam05109  453 HVPTNLTAPASTGPTVSTADVTSPTPAG-TTSGASPVTPSpSPRDNgTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPT 531

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2003 PALAAATTIITCPPSASASTLDQSKDPGP----PRPH------------------RPEAT-PSMASLGPEGEELARVAEG 2059
Cdd:pfam05109  532 PNATSPTLGKTSPTSAVTTPTPNATSPTPavttPTPNatiptlgktsptsavttpTPNATsPTVGETSPQANTTNHTLGG 611

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2060 TSFPP---QEPRH----------------SPQVKMAPTS-----SPAEPHCWPAEAALGTGAEPTCSQAASSKAPSSGSA 2115
Cdd:pfam05109  612 TSSTPvvtSPPKNatsavttgqhnitsssTSSMSLRPSSisetlSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTST 691

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578837041  2116 QPPEGHPGKPEPSRAKSRPLPNMpklviPSAATKfPPEITVTPPTPtllsPKGSISEETKQKLKSAILSAQSAA 2189
Cdd:pfam05109  692 HHVSTSSPAPRPGTTSQASGPGN-----SSTSTK-PGEVNVTKGTP----PKNATSPQAPSGQKTAVPTVTSTG 755

PspC_subgroup_2

NF033839

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

1910-2161

1.66e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 46.69 E-value: 1.66e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1910 RVERIMSETYMLIKQHLPV--KVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRenffpvtvvPTAPDPvp 1987
Cdd:NF033839  229 QIVALIKELDELKKQALSEidNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEPGNKK---------PSAPKP-- 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1988 adsvqrpsdaHTKPRPALAAAttiitcPPSASASTLDQSKDPGPPRPhRPEATPSmaslgPEGEElarvaegTSFPPQEP 2067
Cdd:NF033839  298 ----------GMQPSPQPEKK------EVKPEPETPKPEVKPQLEKP-KPEVKPQ-----PEKPK-------PEVKPQLE 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2068 RHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPSsgsAQPPEGHPgKPEPSRAKSRPLPNMPKLVIPSAA 2147
Cdd:NF033839  349 TPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPE---KPKPEVKP-QPEKPKPEVKPQPEKPKPEVKPQP 424

                         250
                  ....*....|....
gi 578837041 2148 TKFPPEITVTPPTP 2161
Cdd:NF033839  425 EKPKPEVKPQPEKP 438

sucB

TIGR01347

2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This ...

2050-2156

6.63e-04

2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This model describes the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component, dihydrolipoamide acetyltransferase. The seed for this model includes mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N-terminus. They score below the trusted cutoff, but above the noise cutoff and above all examples of dihydrolipoamide acetyltransferase. [Energy metabolism, TCA cycle]

Pssm-ID: 273565 [Multi-domain] Cd Length: 403 Bit Score: 44.34 E-value: 6.63e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2050 GEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHcwPAEAALGTGAEPTCSQAASSKAPSsgSAQPPEGHPG------ 2123
Cdd:TIGR01347   68 GQVLAILEEGNDATAAPPAKSGEEKEETPAASAAAA--PTAAANRPSLSPAARRLAKEHGID--LSAVPGTGVTgrvtke 143

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 578837041  2124 ---KPEPSRAKSRPLPNMPKLVIPSAATKfpPEITV 2156
Cdd:TIGR01347  144 diiKKTEAPASAQPPAAAAAAAAPAAATR--PEERV 177

TPR_12

pfam13424

Tetratricopeptide repeat;

36-119

1.85e-03

Tetratricopeptide repeat;

Pssm-ID: 315987 [Multi-domain] Cd Length: 77 Bit Score: 38.91 E-value: 1.85e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041    36 AFALYHKALDLQKHDRFEESAKAYHELLEaslLREAVSSGDekeglkHPGLILkysTYKNLAQLAAQREDLETAMEFYLE 115
Cdd:pfam13424    3 ATALNNLAAVLRRLGRYDEALELLEKALE---IARRLLGPD------HPLTAT---TLLNLGRLYLELGRYEEALELLER 70


                   ....
gi 578837041   116 AVML 119
Cdd:pfam13424   71 ALAL 74

Name

Accession

Description

Interval

E-value

MEF2_binding

pfam09047

MEF2 binding; The myocyte enhancer factor-2 (MEF2) binding domain, predominantly found in the ...

2162-2196

8.71e-16

Pssm-ID: 370261 [Multi-domain] Cd Length: 35 Bit Score: 72.58 E-value: 8.71e-16

                           10        20        30
                   ....*....|....*....|....*....|....*
gi 578837041  2162 TLLSPKGSISEETKQKLKSAILSAQSAANVRKESL 2196
Cdd:pfam09047    1 TLLSPKGSISEETKQKLKNAILSAQSAANVKKDSL 35

MEF2_binding

cd13839

Mycocyte enhancer factor-2 (MEF2) binding domain of the calcineurin-binding protein cabin-1; ...

2162-2196

5.11e-14

Pssm-ID: 260103 [Multi-domain] Cd Length: 35 Bit Score: 67.79 E-value: 5.11e-14

                          10        20        30
                  ....*....|....*....|....*....|....*
gi 578837041 2162 TLLSPKGSISEETKQKLKSAILSAQSAANVRKESL 2196
Cdd:cd13839     1 TLLSPKGSISEETKQKLKNAILSSQSAANVKKDTL 35

TPR

COG0457

Tetratricopeptide (TPR) repeat [General function prediction only];

30-205

2.36e-11

Tetratricopeptide (TPR) repeat [General function prediction only];

Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 66.18 E-value: 2.36e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   30 EAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEasllreavssgdekeglKHPGLilkYSTYKNLAQLAAQREDLETA 109
Cdd:COG0457     2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE-----------------LDPDD---AEALYNLGLAYLRLGRYEEA 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  110 MEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDC 189
Cdd:COG0457    62 LADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141

                         170
                  ....*....|....*.
gi 578837041  190 RYSKGLVLKEKIFEEQ 205
Cdd:COG0457   142 DDADALYNLGIALEKL 157

TPR

COG0457

Tetratricopeptide (TPR) repeat [General function prediction only];

34-199

4.61e-10

Tetratricopeptide (TPR) repeat [General function prediction only];

Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 62.33 E-value: 4.61e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   34 AEAFALYHKALDLQkhdrfEESAKAYHELleASLLREAvssGDEKEGLKH--------PGLIlkySTYKNLAQLAAQRED 105
Cdd:COG0457    25 EEAIEDYEKALELD-----PDDAEALYNL--GLAYLRL---GRYEEALADyeqaleldPDDA---EALNNLGLALQALGR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  106 LETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKAL 185
Cdd:COG0457    92 YEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLE 171

                         170
                  ....*....|....
gi 578837041  186 EKDCRYSKGLVLKE 199
Cdd:COG0457   172 AAALAALLAAALGE 185

PHA03247

large tegument protein UL36; Provisional

1948-2200

1.58e-09

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 1.58e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1948 GAAAQRQASGDTPTTPKHPKDSRENFfpvtVVPTAPDPVPADSvQRPSDAHTKPRPAlaaATTIITCPPSASASTLDQSK 2027
Cdd:PHA03247 2583 TSRARRPDAPPQSARPRAPVDDRGDP----RGPAPPSPLPPDT-HAPDPPPPSPSPA---ANEPDPHPPPTVPPPERPRD 2654

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2028 DPGPPRPHRP-----EATPSMASLGPEG-------EELARVAEGTSFPPQEPRHSPQvkmAPTSSPAEPhcWPAEAALGT 2095
Cdd:PHA03247 2655 DPAPGRVSRPrrarrLGRAAQASSPPQRprrraarPTVGSLTSLADPPPPPPTPEPA---PHALVSATP--LPPGPAAAR 2729

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2096 GAEPTCSQAASSKAPSSGSAQPpeghpgkPEPSRAKSRPLPNMPklviPSAAtkfPPEITVTPPTPTLLSPKGSISEETK 2175
Cdd:PHA03247 2730 QASPALPAAPAPPAVPAGPATP-------GGPARPARPPTTAGP----PAPA---PPAAPAAGPPRRLTRPAVASLSESR 2795

                         250       260
                  ....*....|....*....|....*
gi 578837041 2176 QKLKSAILSAQSAANVRKESLCQPA 2200
Cdd:PHA03247 2796 ESLPSPWDPADPPAAVLAPAAALPP 2820

Spy

COG3914

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...

30-188

2.28e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 62.70 E-value: 2.28e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   30 EAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEAsllreavssgdekeglkHPGLilkYSTYKNLAQLAAQREDLETA 109
Cdd:COG3914    72 AALLLLAALLELAALLLQALGRYEEALALYRRALAL-----------------NPDN---AEALFNLGNLLLALGRLEEA 131

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578837041  110 MEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKD 188
Cdd:COG3914   132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210

LapB

COG2956

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...

30-205

8.37e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 58.97 E-value: 8.37e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   30 EAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEAS---------LLREAVSSGDEKEGLKHPGLILKYS-----TYKN 95
Cdd:COG2956    70 ERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDpddaealrlLAEIYEQEGDWEKAIEVLERLLKLGpenahAYCE 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   96 LAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYT 175
Cdd:COG2956   150 LAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPE 229

                         170       180       190
                  ....*....|....*....|....*....|
gi 578837041  176 TCLYFICKALEKDCRYSKGLVLKEKIFEEQ 205
Cdd:COG2956   230 EALELLRKALELDPSDDLLLALADLLERKE 259

Herpes_BLLF1

pfam05109

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...

1925-2189

2.63e-08

Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 59.54 E-value: 2.63e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  1925 HLPVKVDEEAALEQAVKFCQVHLGAAAQrQASGDTPTTPK-HPKDS-RENFFPVTVVPTAPDPVPADSVQRPSDAHTKPR 2002
Cdd:pfam05109  453 HVPTNLTAPASTGPTVSTADVTSPTPAG-TTSGASPVTPSpSPRDNgTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPT 531

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2003 PALAAATTIITCPPSASASTLDQSKDPGP----PRPH------------------RPEAT-PSMASLGPEGEELARVAEG 2059
Cdd:pfam05109  532 PNATSPTLGKTSPTSAVTTPTPNATSPTPavttPTPNatiptlgktsptsavttpTPNATsPTVGETSPQANTTNHTLGG 611

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2060 TSFPP---QEPRH----------------SPQVKMAPTS-----SPAEPHCWPAEAALGTGAEPTCSQAASSKAPSSGSA 2115
Cdd:pfam05109  612 TSSTPvvtSPPKNatsavttgqhnitsssTSSMSLRPSSisetlSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTST 691

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578837041  2116 QPPEGHPGKPEPSRAKSRPLPNMpklviPSAATKfPPEITVTPPTPtllsPKGSISEETKQKLKSAILSAQSAA 2189
Cdd:pfam05109  692 HHVSTSSPAPRPGTTSQASGPGN-----SSTSTK-PGEVNVTKGTP----PKNATSPQAPSGQKTAVPTVTSTG 755

PHA03247

large tegument protein UL36; Provisional

1960-2166

4.74e-08

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.80 E-value: 4.74e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1960 PTTPKHPKDSRENFFPVTVVPTAPDPVPADS-VQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPE 2038
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGrVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2039 ATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPSsgSAQPP 2118
Cdd:PHA03247 2709 EPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPR--RLTRP 2786

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 578837041 2119 EGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2166
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSA 2834

BepA

COG4783

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...

33-188

4.80e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 54.04 E-value: 4.80e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   33 EAEAFALYHKALDLQKHDRFEESAKAYHELLEASllreavssGDEKEGlkhpglilkystYKNLAQLAAQREDLETAMEF 112
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELD--------PDNPEA------------FALLGEILLQLGDLDEAIVL 60

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578837041  113 YLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKD 188
Cdd:COG4783    61 LHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136

PHA03247

large tegument protein UL36; Provisional

1980-2162

1.77e-07

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 56.87 E-value: 1.77e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1980 PTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPP-SASAST-LDQSKD--------PGPPRPHRPEATPSMASlgPE 2049
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPqSARPRApVDDRGDprgpappsPLPPDTHAPDPPPPSPS--PA 2634

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2050 GEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGT-GAEPTCSQAASSKAPSSGSAQPPEGHPGKPEPS 2128
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHA 2714

                         170       180       190
                  ....*....|....*....|....*....|....
gi 578837041 2129 RAKSRPLPNMPKlvIPSAATKFPPEITVTPPTPT 2162
Cdd:PHA03247 2715 LVSATPLPPGPA--AARQASPALPAAPAPPAVPA 2746

DUF5585

pfam17823

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.

1949-2189

1.86e-07

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.

Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 56.12 E-value: 1.86e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  1949 AAAQRQASGDTPTTPKHPKdSRENFFPVTVVPTAPDPV----PADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLD 2024
Cdd:pfam17823  120 SSSPSSAAQSLPAAIAALP-SEAFSAPRAAACRANASAapraAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTA 198

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2025 QSKDPGPPRPHRPEATPSMASLGPE-GEELARVAEGTSFPPQEPRHSPQVKMAP-------------------TSSPAEP 2084
Cdd:pfam17823  199 ASSAPATLTPARGISTAATATGHPAaGTALAAVGNSSPAAGTVTAAVGTVTPAAlatlaaaagtvasaagtinMGDPHAR 278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2085 HCWPAEAAlgtgaePTCSQAASSKAPSSGSAQ----------PPEGHPGKPEPSRAKSRPLPNMPKLVIPS--------- 2145
Cdd:pfam17823  279 RLSPAKHM------PSDTMARNPAAPMGAQAQgpiiqvstdqPVHNTAGEPTPSPSNTTLEPNTPKSVASTnlavvtttk 352

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 578837041  2146 AATKFPPEITVtPPTPTLLSPKGSISEETKQklKSAILSAQSAA 2189
Cdd:pfam17823  353 AQAKEPSASPV-PVLHTSMIPEVEATSPTTQ--PSPLLPTQGAA 393

PHA03247

large tegument protein UL36; Provisional

1782-2166

2.30e-07

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 56.49 E-value: 2.30e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1782 SPRagPTEPMDTSEATvchsdlertPPLLPGRPARDRGPESRPTelsleelsiSARQQPTPLTPAQPAPAPAPATTTGTR 1861
Cdd:PHA03247 2574 APR--PSEPAVTSRAR---------RPDAPPQSARPRAPVDDRG---------DPRGPAPPSPLPPDTHAPDPPPPSPSP 2633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1862 AGGHPEEPLSRLSRKRKLLEDTESGKTLLLdAYRVWQQGQKGVAYDLGRVER------IMSETYMLIKQHLPVKVDEEAA 1935
Cdd:PHA03247 2634 AANEPDPHPPPTVPPPERPRDDPAPGRVSR-PRRARRLGRAAQASSPPQRPRrraarpTVGSLTSLADPPPPPPTPEPAP 2712

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1936 lEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRenffpVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP 2015
Cdd:PHA03247 2713 -HALVSATPLPPGPAAARQASPALPAAPAPPAVPA-----GPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2016 PSASASTLDQSKdPGPPRPhrpeATPSMASLGPEGEELARVAEGTSFPPqePRHSPQVKMAPTSSPAEPHCwPAEAALGT 2095
Cdd:PHA03247 2787 AVASLSESRESL-PSPWDP----ADPPAAVLAPAAALPPAASPAGPLPP--PTSAQPTAPPPPPGPPPPSL-PLGGSVAP 2858

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578837041 2096 GAE-----PTCSQAASSKAPSsgsaQPPEGHPGKPEPSRA-KSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2166
Cdd:PHA03247 2859 GGDvrrrpPSRSPAAKPAAPA----RPPVRRLARPAVSRStESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

PHA03247

large tegument protein UL36; Provisional

1949-2200

3.50e-07

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 56.10 E-value: 3.50e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1949 AAAQRQASGDTPTTPKHPKDSRENFFP----VTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASAS--- 2021
Cdd:PHA03247 2752 GGPARPARPPTTAGPPAPAPPAAPAAGpprrLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLppp 2831

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2022 TLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFP-PQEPRHSPQVKMA------PTSSPAEPHCWPAEAALG 2094
Cdd:PHA03247 2832 TSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAkPAAPARPPVRRLArpavsrSTESFALPPDQPERPPQP 2911

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2095 TGAEPTCSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPN-MPKLVIPSAATKFPPEITVT-----PPTPTLLSPKG 2168
Cdd:PHA03247 2912 QAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEpSGAVPQPWLGALVPGRVAVPrfrvpQPAPSREAPAS 2991

                         250       260       270
                  ....*....|....*....|....*....|..
gi 578837041 2169 SISEETKQKLkSAILSAQSAANVRKESLCQPA 2200
Cdd:PHA03247 2992 STPPLTGHSL-SRVSSWASSLALHEETDPPPV 3022

PRK12323

DNA polymerase III subunit gamma/tau;

1954-2159

9.84e-07

DNA polymerase III subunit gamma/tau;

Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 54.11 E-value: 9.84e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1954 QASGDT-PTTPKHPKDSRENffPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASA-STLDQSKDPGP 2031
Cdd:PRK12323  367 QSGGGAgPATAAAAPVAQPA--PAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEAlAAARQASARGP 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2032 PRPHRPEATPSMAslgPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPS 2111
Cdd:PRK12323  445 GGAPAPAPAPAAA---PAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGW 521

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 578837041 2112 SGSAQPpegHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPP 2159
Cdd:PRK12323  522 VAESIP---DPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPP 566

TadD

COG5010

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...

38-188

2.45e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];

Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 49.57 E-value: 2.45e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   38 ALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAV 117
Cdd:COG5010     2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578837041  118 MLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKD 188
Cdd:COG5010    82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152

PilF

COG3063

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];

99-188

4.04e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];

Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 47.09 E-value: 4.04e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   99 LAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARhAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL 178
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 578837041  179 YFICKALEKD 188
Cdd:COG3063    80 AYLERALELD 89

PHA03379

EBNA-3A; Provisional

1954-2199

6.10e-06

EBNA-3A; Provisional

Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 51.60 E-value: 6.10e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1954 QASGDTPTTPKHPKDSrenffPVTVVP----TAPDPVPADSVQRPSDAHTKPRPaLAAATTIITCP-------PSASAST 2022
Cdd:PHA03379  407 KASEPTYGTPRPPVEK-----PRPEVPqsleTATSHGSAQVPEPPPVHDLEPGP-LHDQHSMAPCPvaqlppgPLQDLEP 480

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2023 LDQskDPGPPRPHRPEATPSMASLGP---EGEELARVAEGTSFPPQEPRHSP-QVKMAPTSSPAEPHC-WPAEAALGTGA 2097
Cdd:PHA03379  481 GDQ--LPGVVQDGRPACAPVPAPAGPivrPWEASLSQVPGVAFAPVMPQPMPvEPVPVPTVALERPVCpAPPLIAMQGPG 558

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2098 EPTCS-QAASSKAPSSGSAQPPEghpgKPEPSRAKSRPLPNMPKLVIPSAATKF-PPEITVTPPTPTLLSPKGSISEETK 2175
Cdd:PHA03379  559 ETSGIvRVRERWRPAPWTPNPPR----SPSQMSVRDRLARLRAEAQPYQASVEVqPPQLTQVSPQQPMEYPLEPEQQMFP 634

                         250       260       270
                  ....*....|....*....|....*....|.
gi 578837041 2176 QKLKSAILSAQSAANV-------RKESLCQP 2199
Cdd:PHA03379  635 GSPFSQVADVMRAGGVpamqpqyFDLPLQQP 665

PHA03378

EBNA-3B; Provisional

1958-2202

7.60e-06

EBNA-3B; Provisional

Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 51.22 E-value: 7.60e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1958 DTPTTPKHP---KDSRENFFPVTVVPTAP---DPVPADSVQRPSdAHTKPRPALAAATTIITCPPSASAstldQSKDPGP 2031
Cdd:PHA03378  607 EPPTTQSHIpetSAPRQWPMPLRPIPMRPlrmQPITFNVLVFPT-PHQPPQVEITPYKPTWTQIGHIPY----QPSPTGA 681

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2032 PRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSP-------AEPHCWPAEAALGTGAEPtcSQA 2104
Cdd:PHA03378  682 NTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPgrarppaAAPGRARPPAAAPGRARP--PAA 759

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2105 ASSKAPSSGSA-------QPPEGHPGKPEPSRAKSRPLPnmpklvipsaatkfPPEItvtPPTPTLLSPKGSISEETKQK 2177
Cdd:PHA03378  760 APGRARPPAAApgaptpqPPPQAPPAPQQRPRGAPTPQP--------------PPQA---GPTSMQLMPRAAPGQQGPTK 822

                         250       260
                  ....*....|....*....|....*
gi 578837041 2178 LKSAILSAQSAANVRKESLCQPALE 2202
Cdd:PHA03378  823 QILRQLLTGGVKRGRPSLKKPAALE 847

PHA03307

transcriptional regulator ICP4; Provisional

1949-2192

9.08e-06

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 51.33 E-value: 9.08e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1949 AAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSdahtkPRPALAAATtiitcPPSASASTLDQSKD 2028
Cdd:PHA03307  175 PLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA-----PAPGRSAAD-----DAGASSSDSSSSES 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2029 PGP---PRPHRPEATPSM-ASLGPEGEELARVAEGTSFPPQEPRHSPQVKmAPTSSPAEPHCWPAEAALGTGAEPTCSQA 2104
Cdd:PHA03307  245 SGCgwgPENECPLPRPAPiTLPTRIWEASGWNGPSSRPGPASSSSSPRER-SPSPSPSSPGSGPAPSSPRASSSSSSSRE 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2105 ASSKAPSSGSAQP-PEGHPGKPEPSRAKSRPLPNmpklviPSAATKFPPE-ITVTPPTPTLLSPKGSISEETKQKLKSAI 2182
Cdd:PHA03307  324 SSSSSTSSSSESSrGAAVSPGPSPSRSPSPSRPP------PPADPSSPRKrPRPSRAPSSPAASAGRPTRRRARAAVAGR 397

                         250
                  ....*....|
gi 578837041 2183 LSAQSAANVR 2192
Cdd:PHA03307  398 ARRRDATGRF 407

PRK07003

DNA polymerase III subunit gamma/tau;

1949-2190

1.20e-05

DNA polymerase III subunit gamma/tau;

Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 50.62 E-value: 1.20e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1949 AAAQRQASGDTPTTPKHPKdsrenffPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKD 2028
Cdd:PRK07003  395 AVPAVTAVTGAAGAALAPK-------AAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERD 467

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2029 PGPPRPHRPEATPSMASLGPegeelarvaegtsfPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSK 2108
Cdd:PRK07003  468 AQPPADSGSASAPASDAPPD--------------AAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEAR 533

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2109 APSSGSAQPPEGHPGKPEP-----------SRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSiseeTKQK 2177
Cdd:PRK07003  534 PPTPAAAAPAARAGGAAAAldvlrnagmrvSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAAT----GDAP 609

                         250
                  ....*....|...
gi 578837041 2178 LKSAILSAQSAAN 2190
Cdd:PRK07003  610 PNGAARAEQAAES 622

NlpI

COG4785

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];

29-174

1.29e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 48.76 E-value: 1.29e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   29 KEAQEAEAFALYHKALDLQKHDRF-----EESAKAYHELLEASLLREAVSSGDEK--EGLKHPGLIlkySTYKNLAQLAA 101
Cdd:COG4785     8 LLLALALAAAAASKAAILLAALLFaavlaLAIALADLALALAAAALAAAALAAERidRALALPDLA---QLYYERGVAYD 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578837041  102 QREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDY 174
Cdd:COG4785    85 SLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRY 157

PHA03307

transcriptional regulator ICP4; Provisional

1948-2173

1.42e-05

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.55 E-value: 1.42e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1948 GAAAQRQASGDTPTTPKHPKDSREnfFPVTVVPTAPDPVPADSVQRPSDahtkprPALAAATtiitcPPSASASTLDQSK 2027
Cdd:PHA03307   76 GTEAPANESRSTPTWSLSTLAPAS--PAREGSPTPPGPSSPDPPPPTPP------PASPPPS-----PAPDLSEMLRPVG 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2028 DPGPPRPHRPEATPSMASLGPEGEE-------LARVAEGTSFPPQEPRHSPQVKMAP---TSSPAEPHCWPAEAALGTGA 2097
Cdd:PHA03307  143 SPGPPPAASPPAAGASPAAVASDAAssrqaalPLSSPEETARAPSSPPAEPPPSTPPaaaSPRPPRRSSPISASASSPAP 222

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578837041 2098 EPTCSQAAS-SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPeitvtPPTPTLLSPKGSISEE 2173
Cdd:PHA03307  223 APGRSAADDaGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGP-----SSRPGPASSSSSPRER 294

NrfG

COG4235

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...

95-174

1.89e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 46.15 E-value: 1.89e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   95 NLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDY 174
Cdd:COG4235    22 LLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDY 101

PRK12323

DNA polymerase III subunit gamma/tau;

1993-2174

2.13e-05

DNA polymerase III subunit gamma/tau;

Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 49.87 E-value: 2.13e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1993 RPSDAHTKPRPALAAATTIITCPPSASASTldqskdPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEP----R 2068
Cdd:PRK12323  364 RPGQSGGGAGPATAAAAPVAQPAPAAAAPA------AAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEAlaaaR 437

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2069 HSPQVKMAPTSSPAephcwPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPklvipsaat 2148
Cdd:PRK12323  438 QASARGPGGAPAPA-----PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELP--------- 503

                         170       180
                  ....*....|....*....|....*.
gi 578837041 2149 kfpPEITVTPPTPTLLSPKGSISEET 2174
Cdd:PRK12323  504 ---PEFASPAPAQPDAAPAGWVAESI 526

PRK07764

DNA polymerase III subunits gamma and tau; Validated

1943-2163

2.77e-05

DNA polymerase III subunits gamma and tau; Validated

Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.60 E-value: 2.77e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1943 CQVHLGAAAQRQASGDTPTTPKHPKDSRENffpvTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTiiTCPPSASAST 2022
Cdd:PRK07764  582 WQVEAVVGPAPGAAGGEGPPAPASSGPPEE----AARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAP--GVAAPEHHPK 655

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2023 LDQSKDPGPPRPHRPEATPSMASLGPEGEelarvaegtsfPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPT-C 2101
Cdd:PRK07764  656 HVAVPDASDGGDGWPAKAGGAAPAAPPPA-----------PAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPqA 724

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578837041 2102 SQAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTL 2163
Cdd:PRK07764  725 AQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMA 786

PHA03269

envelope glycoprotein C; Provisional

1983-2143

2.95e-05

envelope glycoprotein C; Provisional

Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 49.34 E-value: 2.95e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1983 PDPVPADSVQrpsdAHTKPRPALAAATTIITCPPSASASTLDQSKDPGP-PRPHrpeatpSMASLGPEgeelarvaegts 2061
Cdd:PHA03269   40 PDPAPAPHQA----ASRAPDPAVAPTSAASRKPDLAQAPTPAASEKFDPaPAPH------QAASRAPD------------ 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2062 fppqePRHSPQVKMAPTSSPAEPhcwPAEAALGTGAEPTCSQAASSKAPSsgsaqpPEGHPGKPEPSRAKSRPLPNMPKL 2141
Cdd:PHA03269   98 -----PAVAPQLAAAPKPDAAEA---FTSAAQAHEAPADAGTSAASKKPD------PAAHTQHSPPPFAYTRSMEHIACT 163


                  ..
gi 578837041 2142 VI 2143
Cdd:PHA03269  164 HG 165

PHA02682

ORF080 virion core protein; Provisional

1975-2081

3.40e-05

ORF080 virion core protein; Provisional

Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 47.93 E-value: 3.40e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1975 PVTVVPTAPDP-VPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHR--PEAT------PSMAS 2045
Cdd:PHA02682   76 PSGQSPLAPSPaCAAPAPACPACAPAAPAPAVTCPAPAPACPPATAPTCPPPAVCPAPARPAPacPPSTrqcppaPPLPT 155

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 578837041 2046 LGPEGEELARVAEGTSFPPQEPRHS-PQVKMAPTSSP 2081
Cdd:PHA02682  156 PKPAPAAKPIFLHNQLPPPDYPAAScPTIETAPAASP 192

TadD

COG5010

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...

1-155

4.03e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];

Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 46.11 E-value: 4.03e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041    1 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKhdRFEESAKAYHELLEAsllreavssgdekeg 80
Cdd:COG5010    21 RTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG--DFEESLALLEQALQL--------------- 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578837041   81 lkHPGlilKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNP 155
Cdd:COG5010    84 --DPN---NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153

dnaA

PRK14086

chromosomal replication initiator protein DnaA;

1977-2167

5.85e-05

chromosomal replication initiator protein DnaA;

Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 48.28 E-value: 5.85e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1977 TVVPTAPDPVPADSVQRPSDAHTKPRPAlaaattiitcpPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARV 2056
Cdd:PRK14086   91 SAGEPAPPPPHARRTSEPELPRPGRRPY-----------EGYGGPRADDRPPGLPRQDQLPTARPAYPAYQQRPEPGAWP 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2057 AEGTSFPPQEPRH---SPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQ-----AASSKAPSSGSAQPPEGHPGKPEPS 2128
Cdd:PRK14086  160 RAADDYGWQQQRLgfpPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRdydhpRPDWDRPRRDRTDRPEPPPGAGHVH 239

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 578837041 2129 RAkSRPLPNMPKLVIPSAATKFP------PEITVTPPTPTL-LSPK 2167
Cdd:PRK14086  240 RG-GPGPPERDDAPVVPIRPSAPgplaaqPAPAPGPGEPTArLNPK 284

PRK07764

DNA polymerase III subunits gamma and tau; Validated

1949-2119

6.98e-05

DNA polymerase III subunits gamma and tau; Validated

Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.06 E-value: 6.98e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1949 AAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPaDSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKD 2028
Cdd:PRK07764  622 AAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVP-DASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQ 700

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2029 PGPPRPHRP------EATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCS 2102
Cdd:PRK07764  701 PAPAPAATPpagqadDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780

                         170
                  ....*....|....*..
gi 578837041 2103 QAASSKAPSSGSAQPPE 2119
Cdd:PRK07764  781 EEEEMAEDDAPSMDDED 797

PHA03381

tegument protein VP22; Provisional

1966-2109

8.13e-05

tegument protein VP22; Provisional

Pssm-ID: 177618 [Multi-domain] Cd Length: 290 Bit Score: 46.93 E-value: 8.13e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1966 PKDSRENFFPVTVVPTAPDPVPAD-SVQRPSDAHTKPRPALAAAT----------TIITCPPSASASTLDQSKDPGPPRP 2034
Cdd:PHA03381   11 PHGTDEVEADVYYDFISPDASPARvSFEEPADRARRGAGQARGRSqaerrfhhydEARADYPYYTGSSSEDERPADPRPS 90

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578837041 2035 HRPEATPSM----ASLGPEGEELARVAEGTSFPPqEPRHSPQVKMAPTSSPAEPHCwPAEAALGTGAEPTCSQAASSKA 2109
Cdd:PHA03381   91 RRPHAQPEAsgpgPARGARGPAGSRGRGRRAESP-SPRDPPNPKGASAPRGRKSAC-ADSAALLDAPAPAAPKRQKTPA 167

PRK13863

T-DNA border endonuclease VirD2;

1944-2133

8.72e-05

T-DNA border endonuclease VirD2;

Pssm-ID: 237533 [Multi-domain] Cd Length: 446 Bit Score: 47.63 E-value: 8.72e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1944 QVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTA-----PDPVPADSVQRPSDAHTKPRPALAAATtiitcppsa 2018
Cdd:PRK13863  258 EVRLQEPAGSSIKADARIRVSLESERRAQPSASKIPVADdfgieTSYVAEGDVRKLEGNSGTPRLATEVAT--------- 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2019 sASTLDQSkdPGPPRPHRPEATPSMASLGpegeELARVAEGTSFPPQEP--RHSPQVKMAPTSSPAEPHCwPAEAALGTG 2096
Cdd:PRK13863  329 -HTTSERQ--QRRKRPRDDEGEPSGAKRT----RLNGIAVGPEANAGEQdgRDDPITSPAQPPRSNPLAD-PVRASIATD 400

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 578837041 2097 AEPTCSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSR 2133
Cdd:PRK13863  401 SLPATADRQQQREPSSKRPRDDDGEPSIRKRARDGRS 437

PLN03209

translocon at the inner envelope of chloroplast subunit 62; Provisional

1963-2166

1.05e-04

translocon at the inner envelope of chloroplast subunit 62; Provisional

Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 47.23 E-value: 1.05e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1963 PKHPkDSRENFFPVTVVPTAPD-PVPADSVQRPSDAHTKPRPA--------LAAATTIITCPPS---ASASTLDQSKDPG 2030
Cdd:PLN03209  330 PKES-DAADGPKPVPTKPVTPEaPSPPIEEEPPQPKAVVPRPLspytayedLKPPTSPIPTPPSsspASSKSVDAVAKPA 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2031 PPRPH-RPEATPSMASLGPEGEELARVAEGTSF-------PPQEPRHSPQVKMAPTSS-----PAEPHCWPAEAALGTGA 2097
Cdd:PLN03209  409 EPDVVpSPGSASNVPEVEPAQVEAKKTRPLSPYaryedlkPPTSPSPTAPTGVSPSVSstssvPAVPDTAPATAATDAAA 488

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2098 EPTCSQAASSKAPSSGSAQPPEG-HPGKPEPSRAKSRPlPNMPKLVIPSAATKFPPEITVTPPTPTLLSP 2166
Cdd:PLN03209  489 PPPANMRPLSPYAVYDDLKPPTSpSPAAPVGKVAPSST-NEVVKVGNSAPPTALADEQHHAQPKPRPLSP 557

PRK12727

flagellar biosynthesis protein FlhF;

1976-2161

1.56e-04

flagellar biosynthesis protein FlhF;

Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 46.91 E-value: 1.56e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1976 VTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSA-----SASTLDQSKDPGPPRPhRPEATPSMASLGPEG 2050
Cdd:PRK12727   62 TPATAAAPAPAPQAPTKPAAPVHAPLKLSANANMSQRQRVASAaedmiAAMALRQPVSVPRQAP-AAAPVRAASIPSPAA 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2051 EELARVAEGTSFPPQE----PRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPG-KP 2125
Cdd:PRK12727  141 QALAHAAAVRTAPRQEhalsAVPEQLFADFLTTAPVPRAPVQAPVVAAPAPVPAIAAALAAHAAYAQDDDEQLDDDGfDL 220

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 578837041 2126 EPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTP 2161
Cdd:PRK12727  221 DDALPQILPPAALPPIVVAPAAPAALAAVAAAAPAP 256

PspC_subgroup_2

NF033839

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...

1910-2161

1.66e-04

Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 46.69 E-value: 1.66e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1910 RVERIMSETYMLIKQHLPV--KVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRenffpvtvvPTAPDPvp 1987
Cdd:NF033839  229 QIVALIKELDELKKQALSEidNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEPGNKK---------PSAPKP-- 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1988 adsvqrpsdaHTKPRPALAAAttiitcPPSASASTLDQSKDPGPPRPhRPEATPSmaslgPEGEElarvaegTSFPPQEP 2067
Cdd:NF033839  298 ----------GMQPSPQPEKK------EVKPEPETPKPEVKPQLEKP-KPEVKPQ-----PEKPK-------PEVKPQLE 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2068 RHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPSsgsAQPPEGHPgKPEPSRAKSRPLPNMPKLVIPSAA 2147
Cdd:NF033839  349 TPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPE---KPKPEVKP-QPEKPKPEVKPQPEKPKPEVKPQP 424

                         250
                  ....*....|....
gi 578837041 2148 TKFPPEITVTPPTP 2161
Cdd:NF033839  425 EKPKPEVKPQPEKP 438

PHA03307

transcriptional regulator ICP4; Provisional

1981-2169

1.84e-04

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.09 E-value: 1.84e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1981 TAPDPVPAdsvqrPSDAHTKPRPALAAATTIITCPP-SASASTLDQSKDPGPPRPHRPEATPSMASLGpegeELARVAEG 2059
Cdd:PHA03307  254 ECPLPRPA-----PITLPTRIWEASGWNGPSSRPGPaSSSSSPRERSPSPSPSSPGSGPAPSSPRASS----SSSSSRES 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2060 TSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHP-------GKPEPSRAKS 2132
Cdd:PHA03307  325 SSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRrraraavAGRARRRDAT 404

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 578837041 2133 RPLPNMPKLVIPSAATKFPPEITVTPPtptLLSPKGS 2169
Cdd:PHA03307  405 GRFPAGRPRPSPLDAGAASGAFYARYP---LLTPSGE 438

PHA03307

transcriptional regulator ICP4; Provisional

1975-2171

1.92e-04

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 46.70 E-value: 1.92e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1975 PVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAA-----TTIITCPPSASASTLDQSKDPGPpRPHRPEATPSMASLGPE 2049
Cdd:PHA03307   25 PATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGaaacdRFEPPTGPPPGPGTEAPANESRS-TPTWSLSTLAPASPARE 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2050 GEELARVAEGTSFPPQ-EPRHSPqvkmAPTSSPAEPHCWPAEAALGTGAeptcsqAASSKAPSSGSAQPPEGHPGKPEPS 2128
Cdd:PHA03307  104 GSPTPPGPSSPDPPPPtPPPASP----PPSPAPDLSEMLRPVGSPGPPP------AASPPAAGASPAAVASDAASSRQAA 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 578837041 2129 RAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSIS 2171
Cdd:PHA03307  174 LPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISAS 216

Atrophin-1

pfam03154

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...

1943-2167

2.19e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.

Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.68 E-value: 2.19e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  1943 CQVHLGAAAQRQASGDTPTTPKHPKDSREnffPVTVVPTAPDPV--PADSVQRPSDAHTKPRPALAAATTIITCPPsasa 2020
Cdd:pfam03154  184 PSPPPPGTTQAATAGPTPSAPSVPPQGSP---ATSQPPNQTQSTaaPHTLIQQTPTLHPQRLPSPHPPLQPMTQPP---- 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2021 stldqskdpgPPRPHRPEATPSMASLGPegeelarvaegtsFPPQEprHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPT 2100
Cdd:pfam03154  257 ----------PPSQVSPQPLPQPSLHGQ-------------MPPMP--HSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPP 311

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578837041  2101 CSQAASSKAPSSGSAQPP-EGHPGKPEPSRakSRPLPNMPkLVIPSAAtkfPPEITVTPPTPTLLSPK 2167
Cdd:pfam03154  312 GPSPAAPGQSQQRIHTPPsQSQLQSQQPPR--EQPLPPAP-LSMPHIK---PPPTTPIPQLPNPQSHK 373

PHA03247

large tegument protein UL36; Provisional

1948-2135

2.76e-04

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.76e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1948 GAAAQRQASGD---TPTTPKHPKDSRENFFPVTvVPTAPDPVPADSVQRPSdahtkprpalaaattiitcPPSASASTLD 2024
Cdd:PHA03247 2860 GDVRRRPPSRSpaaKPAAPARPPVRRLARPAVS-RSTESFALPPDQPERPP-------------------QPQAPPPPQP 2919

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2025 QSKDPGPPRPHRPEATPSMaslgpegeelarvaegtsfPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEP--TCS 2102
Cdd:PHA03247 2920 QPQPPPPPQPQPPPPPPPR-------------------PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPrfRVP 2980

                         170       180       190
                  ....*....|....*....|....*....|...
gi 578837041 2103 QAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPL 2135
Cdd:PHA03247 2981 QPAPSREAPASSTPPLTGHSLSRVSSWASSLAL 3013

PRK12323

DNA polymerase III subunit gamma/tau;

1987-2190

3.19e-04

DNA polymerase III subunit gamma/tau;

Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 46.02 E-value: 3.19e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1987 PADSVQRPSDAhtkPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHR---PEATPSMASLGPEGEELARVAEGTSFP 2063
Cdd:PRK12323  374 PATAAAAPVAQ---PAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAaapARRSPAPEALAAARQASARGPGGAPAP 450

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2064 PQEPRHSPqvkmAPTSSPAEPHcwPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPGK-PEPSRAKSRPLPNM---- 2138
Cdd:PRK12323  451 APAPAAAP----AAAARPAAAG--PRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEfASPAPAQPDAAPAGwvae 524

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 578837041 2139 ----PKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAAN 2190
Cdd:PRK12323  525 sipdPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGD 580

PHA03307

transcriptional regulator ICP4; Provisional

1971-2127

3.26e-04

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 46.32 E-value: 3.26e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1971 ENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAattiitcPPSASASTLDQSKDPGPPrphrPEATPSMASLGP-E 2049
Cdd:PHA03307   62 CDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPA-------SPAREGSPTPPGPSSPDP----PPPTPPPASPPPsP 130

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578837041 2050 GEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPGKPEP 2127
Cdd:PHA03307  131 APDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPR 208

PRK12323

DNA polymerase III subunit gamma/tau;

1927-2119

4.96e-04

DNA polymerase III subunit gamma/tau;

Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.25 E-value: 4.96e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1927 PVKVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADS-----VQRPSDAHTKP 2001
Cdd:PRK12323  392 PAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAaapaaAARPAAAGPRP 471

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2002 RPALAAATTIITCPPSASAStldqSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPP--QEPRHSPQVKMAPTS 2079
Cdd:PRK12323  472 VAAAAAAAPARAAPAAAPAP----ADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPAtaDPDDAFETLAPAPAA 547

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 578837041 2080 SPAEphcwPAEAALGTGAEPTCSQAASSKAPSSGSAQPPE 2119
Cdd:PRK12323  548 APAP----RAAAATEPVVAPRPPRASASGLPDMFDGDWPA 583

PilF

COG3063

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];

92-158

5.80e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];

Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 40.92 E-value: 5.80e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578837041   92 TYKNLAQLAAQREDLETAMEFyLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHW 158
Cdd:COG3063    28 ALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSAL 93

PRK12323

DNA polymerase III subunit gamma/tau;

1950-2134

6.34e-04

DNA polymerase III subunit gamma/tau;

Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 6.34e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1950 AAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPA------DSVQRPSDAHTKPRPALAAATTIITCPPSASASTL 2023
Cdd:PRK12323  393 AAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEalaaarQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPV 472

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2024 DQSKDPGPPRPHRPEATPSMASLGPEGEELarvaegtsfPPQEPRHSP-QVKMAPTSSPAEPHCWPAEAALGTGAEPTCS 2102
Cdd:PRK12323  473 AAAAAAAPARAAPAAAPAPADDDPPPWEEL---------PPEFASPAPaQPDAAPAGWVAESIPDPATADPDDAFETLAP 543

                         170       180       190
                  ....*....|....*....|....*....|..
gi 578837041 2103 QAASSKAPSSGSAQPPEGHPGKPEPSRAKSRP 2134
Cdd:PRK12323  544 APAAAPAPRAAAATEPVVAPRPPRASASGLPD 575

sucB

TIGR01347

2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This ...

2050-2156

6.63e-04

Pssm-ID: 273565 [Multi-domain] Cd Length: 403 Bit Score: 44.34 E-value: 6.63e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2050 GEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHcwPAEAALGTGAEPTCSQAASSKAPSsgSAQPPEGHPG------ 2123
Cdd:TIGR01347   68 GQVLAILEEGNDATAAPPAKSGEEKEETPAASAAAA--PTAAANRPSLSPAARRLAKEHGID--LSAVPGTGVTgrvtke 143

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 578837041  2124 ---KPEPSRAKSRPLPNMPKLVIPSAATKfpPEITV 2156
Cdd:TIGR01347  144 diiKKTEAPASAQPPAAAAAAAAPAAATR--PEERV 177

PRK10263

DNA translocase FtsK; Provisional

1956-2175

7.98e-04

DNA translocase FtsK; Provisional

Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 44.69 E-value: 7.98e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1956 SGDTPTTPKHPK-DSRENFFPVT--VVPTAPDPVPADSVQRPSDAHTkPRPALAAATTIITCPpsasasTLDQSKDPGPp 2032
Cdd:PRK10263  295 SGNRATQPEYDEyDPLLNGAPITepVAVAAAATTATQSWAAPVEPVT-QTPPVASVDVPPAQP------TVAWQPVPGP- 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2033 rpHRPEatPSMAslgPEGEELARVAEGTSfpPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAePTCSQAASSKAPSS 2112
Cdd:PRK10263  367 --QTGE--PVIA---PAPEGYPQQSQYAQ--PAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYA-PAPEQPAQQPYYAP 436

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578837041 2113 GSAQPPEGHPGKPEPSRAKSRPLPN-MPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETK 2175
Cdd:PRK10263  437 APEQPVAGNAWQAEEQQSTFAPQSTyQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETK 500

PHA03325

nuclear-egress-membrane-like protein; Provisional

2018-2169

8.51e-04

nuclear-egress-membrane-like protein; Provisional

Pssm-ID: 223044 Cd Length: 418 Bit Score: 44.10 E-value: 8.51e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2018 ASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQ-----VKMAPTSSPAEPhcwPAEAA 2092
Cdd:PHA03325  259 SSAFMLNSSLPTSAPKRRSRRAGAMRAAAGETADLADDDGSEHSDPEPLPASLPPppvrrPRVKHPEAGKEE---PDGAR 335

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578837041 2093 LGTGAEPTCSqAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPsaATKFPPEITVTPPTPTLLSPKGS 2169
Cdd:PHA03325  336 NAEAKEPAQP-ATSTSSKGSSSAQNKDSGSTGPGSSLAAASSFLEDDDFGSP--PLDLTTSLRHMPSPSVTSAPEPP 409

PHA03379

EBNA-3A; Provisional

1924-2170

9.16e-04

EBNA-3A; Provisional

Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 44.66 E-value: 9.16e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1924 QHLPVKVDEEAALEQAVK--FCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKP 2001
Cdd:PHA03379  436 SHGSAQVPEPPPVHDLEPgpLHDQHSMAPCPVAQLPPGPLQDLEPGDQLPGVVQDGRPACAPVPAPAGPIVRPWEASLSQ 515

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2002 RPALAAATTIitcpPSASASTLDQSKDPGPPRPHRPeATPSMASLGP-EGEELARVAE---GTSFPPQEPRHSPQVKMAP 2077
Cdd:PHA03379  516 VPGVAFAPVM----PQPMPVEPVPVPTVALERPVCP-APPLIAMQGPgETSGIVRVRErwrPAPWTPNPPRSPSQMSVRD 590

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2078 TSSPAEPHCWPAEAALGTgaEPTCSQAASSKAPSSGSAQPPEG-HPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITV 2156
Cdd:PHA03379  591 RLARLRAEAQPYQASVEV--QPPQLTQVSPQQPMEYPLEPEQQmFPGSPFSQVADVMRAGGVPAMQPQYFDLPLQQPISQ 668

                         250
                  ....*....|....
gi 578837041 2157 TPPTPTLLSPKGSI 2170
Cdd:PHA03379  669 GAPLAPLRASMGPV 682

Atrophin-1

pfam03154

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...

1991-2161

1.65e-03

Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 43.60 E-value: 1.65e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  1991 VQRPSDAHTKPRPALAAATTIITCPPSASASTLD-QSKDPGPPRPHRPEATPSMASLGPEGEELarvaegtsFPPQEPR- 2068
Cdd:pfam03154  174 LQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPpQGSPATSQPPNQTQSTAAPHTLIQQTPTL--------HPQRLPSp 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041  2069 HSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNmPKLVIPSAAT 2148
Cdd:pfam03154  246 HPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPS-PAAPGQSQQR 324

                          170
                   ....*....|...
gi 578837041  2149 KFPPEITVTPPTP 2161
Cdd:pfam03154  325 IHTPPSQSQLQSQ 337

PRK13108

prolipoprotein diacylglyceryl transferase; Reviewed

1984-2168

1.79e-03

prolipoprotein diacylglyceryl transferase; Reviewed

Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 43.43 E-value: 1.79e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1984 DPVPADSVQRPSDAHTKPRPALAAATTIitcppsASASTLDQSKDPGPP-RPHRPEATPSMASLGPEGEELARVAEGTSF 2062
Cdd:PRK13108  281 APGALRGSEYVVDEALEREPAELAAAAV------ASAASAVGPVGPGEPnQPDDVAEAVKAEVAEVTDEVAAESVVQVAD 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2063 PPQEPRHSPQVKMAPTSSPAEPHCWPAEAAlgtgAEPTCSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKlv 2142
Cdd:PRK13108  355 RDGESTPAVEETSEADIEREQPGDLAGQAP----AAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPAK-- 428

                         170       180
                  ....*....|....*....|....*.
gi 578837041 2143 ipsaatkfPPEITVTPPTPTLLSPKG 2168
Cdd:PRK13108  429 --------PDELAVAGPGDDPAEPDG 446

TPR_12

pfam13424

Tetratricopeptide repeat;

36-119

1.85e-03

Tetratricopeptide repeat;

Pssm-ID: 315987 [Multi-domain] Cd Length: 77 Bit Score: 38.91 E-value: 1.85e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041    36 AFALYHKALDLQKHDRFEESAKAYHELLEaslLREAVSSGDekeglkHPGLILkysTYKNLAQLAAQREDLETAMEFYLE 115
Cdd:pfam13424    3 ATALNNLAAVLRRLGRYDEALELLEKALE---IARRLLGPD------HPLTAT---TLLNLGRLYLELGRYEEALELLER 70


                   ....
gi 578837041   116 AVML 119
Cdd:pfam13424   71 ALAL 74

PHA03291

envelope glycoprotein I; Provisional

1973-2167

3.02e-03

envelope glycoprotein I; Provisional

Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 42.25 E-value: 3.02e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1973 FFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTiiTCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEE 2052
Cdd:PHA03291  203 FVPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPST--TIAAPQAGTTPEAEGTPAPPTPGGGEAPPANATPAPEASR 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2053 -----------------LARVAEGTSF-----PPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGT-GAEptcsqaasska 2109
Cdd:PHA03291  281 yeltvtqiiqiaipasiIACVFLGSCAcclhrRCRRRRRRPARIYRPPSPVAPSISAVNEAALARlGDE----------- 349

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578837041 2110 pssgsaqpPEGHPGKPePSRAKSRPLPN-MPKLVIPSAATKFP--PEITVTPPTPTLLSPK 2167
Cdd:PHA03291  350 --------LKRHPPES-PRRSKRRSSQTmVPSLTAISEESEAPavVELSRSPRRPGGPTAR 401

PLN03237

DNA topoisomerase 2; Provisional

1927-2134

3.17e-03

DNA topoisomerase 2; Provisional

Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 42.93 E-value: 3.17e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1927 PVKVDEEAALEQAVKFCQVHLGAAAQrqASGDTPTTPKHPKDSRENFFPVtvvPTAPDPVPADSVQRPSDAHTKPRPAla 2006
Cdd:PLN03237 1255 KEKEEEDEILDLKDRLAAYNLDSAPA--QSAKMEETVKAVPARRAAARKK---PLASVSVISDSDDDDDDFAVEVSLA-- 1327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2007 aATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLgpEGEELARVAEGTSFPPQEPRhspqvKMAPTSSPAEphc 2086
Cdd:PLN03237 1328 -ERLKKKGGRKPAAANKKAAKPPAAAKKRGPATVQSGQKL--LTEMLKPAEAIGISPEKKVR-----KMRASPFNKK--- 1396

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 578837041 2087 wpAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSRP 2134
Cdd:PLN03237 1397 --SGSVLGRAATNKETESSENVSGSSSSEKDEIDVSAKPRPQRANRKQ 1442

PHA03307

transcriptional regulator ICP4; Provisional

2004-2176

3.17e-03

transcriptional regulator ICP4; Provisional

Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.85 E-value: 3.17e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2004 ALAAATTIITCPPSASAstlDQSKDP--GPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHspqvkMAPTSSP 2081
Cdd:PHA03307   13 AAAEGGEFFPRPPATPG---DAADDLlsGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGT-----EAPANES 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2082 AEPHCWPAEAALGTGAEPTCSQAASSkaPSSGSAQPPEGHPGKPEPSRA-------KSRPLPNMPKLVIPSAATKFPPEI 2154
Cdd:PHA03307   85 RSTPTWSLSTLAPASPAREGSPTPPG--PSSPDPPPPTPPPASPPPSPApdlsemlRPVGSPGPPPAASPPAAGASPAAV 162

                         170       180
                  ....*....|....*....|..
gi 578837041 2155 TVTPPTPTLLSPKGSISEETKQ 2176
Cdd:PHA03307  163 ASDAASSRQAALPLSSPEETAR 184

LapB

COG2956

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...

34-174

3.57e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 41.64 E-value: 3.57e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041   34 AEAFALYHKALDLQKHDRFEESAKAYHELLEasllreavssgdekeglKHPGLIlkySTYKNLAQLAAQREDLETAMEFY 113
Cdd:COG2956     6 AAALGWYFKGLNYLLNGQPDKAIDLLEEALE-----------------LDPETV---EAHLALGNLYRRRGEYDRAIRIH 65

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578837041  114 LEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDY 174
Cdd:COG2956    66 QKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW 126

TPR_21

pfam09976

Tetratricopeptide repeat-like domain; This family resembles a single unit of a TPR repeat.

48-151

3.60e-03

Tetratricopeptide repeat-like domain; This family resembles a single unit of a TPR repeat.

Pssm-ID: 430959 [Multi-domain] Cd Length: 194 Bit Score: 41.03 E-value: 3.60e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041    48 KHDRFEESAKAYHELLEAsllreaVSSGDEKEGL--------KHPGlilkySTYKNLAQL-----AAQREDLETAMEfYL 114
Cdd:pfam09976   32 QRSQAEEASALYQQLLEA------VAAGDAAKAQaaaaqlkdEYGG-----TGYAALAALllakaAVEAGDLAAAKA-QL 99

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 578837041   115 EAVMLDSTDVNLwykiGHVA-LRLIRIPLARHAFEEGL 151
Cdd:pfam09976  100 EWVADNAKDEAL----KALArLRLARVLLAQGKYDEAL 133

PRK14951

DNA polymerase III subunits gamma and tau; Provisional

1993-2123

4.48e-03

DNA polymerase III subunits gamma and tau; Provisional

Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.01 E-value: 4.48e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1993 RPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPhRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQ 2072
Cdd:PRK14951  365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAA-PAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 578837041 2073 VKMAPTSSPAEPHCWPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPG 2123
Cdd:PRK14951  444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494

PRK14951

DNA polymerase III subunits gamma and tau; Provisional

2002-2200

4.52e-03

DNA polymerase III subunits gamma and tau; Provisional

Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.01 E-value: 4.52e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2002 RPALAAATtiitcPPSASASTldqskdpgpprPHRPEATPSMASlgpegeelarvaegtsfpPQEPRHSPQVKMAPTSSP 2081
Cdd:PRK14951  365 KPAAAAEA-----AAPAEKKT-----------PARPEAAAPAAA------------------PVAQAAAAPAPAAAPAAA 410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2082 AEPHCWPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAAtkfPPEITVTPPTP 2161
Cdd:PRK14951  411 ASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAA---PAPAAAPAAAR 487

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 578837041 2162 TLLSPKGSISEETKQKLKSAI--------LSAQS---AAN-------VRKESLCQPA 2200
Cdd:PRK14951  488 LTPTEEGDVWHATVQQLAAAEaitalareLALQSelvARDgdqwllrVERESLNQPG 544

PHA03247

large tegument protein UL36; Provisional

1771-2163

4.60e-03

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 4.60e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1771 ADQSGERKDKESPRAGPTEPmdTSEATVCH-SDLERTPPllPGRPardrgPESRPTELS----LEELSISARQQ--PTPL 1843
Cdd:PHA03247 2667 ARRLGRAAQASSPPQRPRRR--AARPTVGSlTSLADPPP--PPPT-----PEPAPHALVsatpLPPGPAAARQAspALPA 2737

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1844 TPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKrklledtesgktllldayrvwqqgqkgvaydlgrverimsetymlik 1923
Cdd:PHA03247 2738 APAPPAVPAGPATPGGPARPARPPTTAGPPAPA----------------------------------------------- 2770

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1924 qhlPVKVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSdahtkPRP 2003
Cdd:PHA03247 2771 ---PPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAP-----PPP 2842

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2004 AlaaattiitcPPSASASTLDQSKDPGPP----RPHRPEATPSMASLGPEGEELARVA-----EGTSFPPQEPRHSPQVK 2074
Cdd:PHA03247 2843 P----------GPPPPSLPLGGSVAPGGDvrrrPPSRSPAAKPAAPARPPVRRLARPAvsrstESFALPPDQPERPPQPQ 2912

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2075 MAPTSSPAEPhcwPAEAALGTGAEPTCSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSRP-LPNMPKLVIPSAAtkfPPE 2153
Cdd:PHA03247 2913 APPPPQPQPQ---PPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPgRVAVPRFRVPQPA---PSR 2986

                         410
                  ....*....|
gi 578837041 2154 ITVTPPTPTL 2163
Cdd:PHA03247 2987 EAPASSTPPL 2996

PRK07764

DNA polymerase III subunits gamma and tau; Validated

2029-2130

5.83e-03

DNA polymerase III subunits gamma and tau; Validated

Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.90 E-value: 5.83e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2029 PGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPP-QEPRHSPQVKMAPTSSPAEPHCWPAEAALGTgAEPTCSQAASS 2107
Cdd:PRK07764  396 AAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPaPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPS-AQPAPAPAAAP 474

                          90       100
                  ....*....|....*....|...
gi 578837041 2108 KAPSSGSAQPPEGHPGKPEPSRA 2130
Cdd:PRK07764  475 EPTAAPAPAPPAAPAPAAAPAAP 497

PHA03247

large tegument protein UL36; Provisional

1963-2161

7.80e-03

large tegument protein UL36; Provisional

Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 7.80e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1963 PKHPKDSREnffPVTVVPTAPDPVPADSVQRPSDAHTKPrpalaaattiitcPPSASASTLDQSKDPGPPRPhrpeatPS 2042
Cdd:PHA03247 2475 PGAPVYRRP---AEARFPFAAGAAPDPGGGGPPDPDAPP-------------APSRLAPAILPDEPVGEPVH------PR 2532

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2043 MASLGPEGEELARVAEGTSFPPQEPRHSPQV--KMAPTSSPAEPHCWPAEAALGT--GAEPtcsQAASSKAPSSGSAQPP 2118
Cdd:PHA03247 2533 MLTWIRGLEELASDDAGDPPPPLPPAAPPAApdRSVPPPRPAPRPSEPAVTSRARrpDAPP---QSARPRAPVDDRGDPR 2609

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 578837041 2119 -EGHPGKPEPSRAKSRPLPNMPKlviPSAATKFPPEITVTPPTP 2161
Cdd:PHA03247 2610 gPAPPSPLPPDTHAPDPPPPSPS---PAANEPDPHPPPTVPPPE 2650

PRK07994

DNA polymerase III subunits gamma and tau; Validated

1993-2195

8.61e-03

DNA polymerase III subunits gamma and tau; Validated

Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 41.39 E-value: 8.61e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 1993 RPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPrPHRPEATPSMASLGPEGEELARVAEGTsfpPQEPRHSPQ 2072
Cdd:PRK07994  360 HPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAV-PPPPASAPQQAPAVPLPETTSQLLAAR---QQLQRAQGA 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578837041 2073 VKmAPTSSPAEPhcwpaeaalgTGAEPTcSQAASSKAPSSGSAQPPEGHPGKPEPSRAKSR-PLPNMPKLVIPSAATKFP 2151
Cdd:PRK07994  436 TK-AKKSEPAAA----------SRARPV-NSALERLASVRPAPSALEKAPAKKEAYRWKATnPVEVKKEPVATPKALKKA 503

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 578837041 2152 PEITVTPPTPTLLSPKGSISE---ETKQKLKSAILSAQSAANVRKES 2195
Cdd:PRK07994  504 LEHEKTPELAAKLAAEAIERDpwaALVSQLGLPGLVEQLALNAWKEE 550

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01